Category: Amgen

Scientist – RNA Bioinformatics (US-Remote) job with Amgen

HOW MIGHT YOU DEFY IMAGINATION? Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that…

Continue Reading Scientist – RNA Bioinformatics (US-Remote) job with Amgen

NVIDIA Corp. (NVDA) Q1 2024 Earnings Call Transcript

NVIDIA Corp. (NASDAQ:NVDA) Q1 2024 Earnings Conference Call May 24, 2023 5:00 PM ET Company Participants Simona Jankowski – VP, IR Colette Kress – EVP & CFO Jensen Huang – Co-Founder, CEO & President Conference Call Participants Toshiya Hari – Goldman Sachs C.J. Muse – Evercore ISI Vivek Arya –…

Continue Reading NVIDIA Corp. (NVDA) Q1 2024 Earnings Call Transcript

Nvidia (NVDA) Q1 2024 Earnings Call Transcript

Image source: The Motley Fool. Nvidia (NVDA -0.49%)Q1 2024 Earnings CallMay 24, 2023, 4:45 p.m. ET Contents: Prepared Remarks Questions and Answers Call Participants Prepared Remarks: Operator Good afternoon. My name is David, and I’ll be your conference operator today. At this time, I’d like to welcome everyone to NVIDIA’s first-quarter earnings…

Continue Reading Nvidia (NVDA) Q1 2024 Earnings Call Transcript

Molecular Diagnostics Market Poised To Reach USD 23.90 Billion By 2030, Driven By Impressive 9.86% CAGR

(MENAFN– EIN Presswire) Molecular Diagnostics Market Growth Increase in the prevalence of infectious diseases and various types of cancer drives the growth of the molecular diagnostics market. PORTLAND, OREGON, UNITED STATES, May 24, 2023 /einpresswire.com / — Allied Market Research published a report, titled, “molecular diagnostics market by Type (Instruments,…

Continue Reading Molecular Diagnostics Market Poised To Reach USD 23.90 Billion By 2030, Driven By Impressive 9.86% CAGR

Amgen hiring Scientist – RNA Bioinformatics (US-Remote) in San Francisco, California, United States

Career CategoryResearchJob DescriptionHOW MIGHT YOU DEFY IMAGINATION?You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all…

Continue Reading Amgen hiring Scientist – RNA Bioinformatics (US-Remote) in San Francisco, California, United States

Global Biotechnology Market Size & Share to Surpass $2772.7 Billion by 2030

Global Biotechnology Market Size & Share to Surpass $2772.7 Billion by 2030 | Vantage Market Research WASHINGTON, May 22, 2023 (GLOBE NEWSWIRE) — The Global Biotechnology Market is valued at USD 1094.6 Billion in 2022 and is projected to reach a value of USD 2772.7 Billion by 2030 at a…

Continue Reading Global Biotechnology Market Size & Share to Surpass $2772.7 Billion by 2030

Arrowhead Pharmaceuticals Remains A Buy For Pipeline Potential (NASDAQ:ARWR)

luismmolina Arrowhead Pharmaceuticals (NASDAQ:ARWR) is a clinical-stage biotechnology company with a wide pipeline of potential RNAi therapies. It is getting into the home stretch now, with three Phase 3 trials in progress, plus three each of Phase 1 and Phase 2 trials, and several pre-clinical candidates. Since I last discussed…

Continue Reading Arrowhead Pharmaceuticals Remains A Buy For Pipeline Potential (NASDAQ:ARWR)

Cancer Gene Therapy Market : Opportunity Analysis and Industry Forecast 2030 | CAGR 23.3%

Cancer gene therapy is a technique used for the treatment of cancer where therapeutic DNA is being introduced into the gene of the patient with cancer. Owing to the high success rate during the preclinical and clinical trials, cancer gene therapy has gained popularity. There are many techniques used for…

Continue Reading Cancer Gene Therapy Market : Opportunity Analysis and Industry Forecast 2030 | CAGR 23.3%

DLBCL: Major new treatment breakthroughs

Diffuse large B-cell lymphoma (DLBCL) made headlines earlier this year with the high-profile case of prominent U.S. Congressman Jamie Raskin (D-MD). Yet, until very recently, progress in treating this most common form of lymphoma has been stalled for more than 2 decades. Significant breakthroughs have come in just the past…

Continue Reading DLBCL: Major new treatment breakthroughs

Babylon Health ‘may Trade To Zero’

InnovationRx is your weekly digest of healthcare news. To get it in your inbox, subscribe here. Ali Parsa, founder and chief executive officer of Babylon Holdings Limited. © 2022 Bloomberg Finance LP Babylon Holdings Limited, a U.K. and Austin, Texas-based digital health company that went public in a 2021 SPAC…

Continue Reading Babylon Health ‘may Trade To Zero’

Beyond Alphafold: AI Excels At Creating New Proteins

Ian Haydon Proteins designed with an ultra-rapid software tool called ProteinMPNN were much more likely to fold up as intended. Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design. In the new papers, biologists at…

Continue Reading Beyond Alphafold: AI Excels At Creating New Proteins

Dr Khalil on Benefits Derived From the POSEIDON Regimen in Metastatic NSCLC

Maya Khalil, MD, assistant professor of medicine, Division of Hematology and Oncology, the University of Alabama at Birmingham (UAB), oncologist, O’Neal Comprehensive Cancer Center, UAB Medicine, discusses the use of first-line durvalumab (Imfinzi) plus tremelimumab (Imjudo) in patients with non–small cell lung cancer (NSCLC) enrolled in the phase 3 POSEIDON trial…

Continue Reading Dr Khalil on Benefits Derived From the POSEIDON Regimen in Metastatic NSCLC

Biotechnology Market 2022-2031 is Driven by Increasing Demand for Better and More Effective Treatments for Diseases

PRESS RELEASE Published May 11, 2023 Biotechnology is the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services. Today, biotechnology is being used to create new and improved crop varieties, develop renewable fuels, and create new industrial and consumer products….

Continue Reading Biotechnology Market 2022-2031 is Driven by Increasing Demand for Better and More Effective Treatments for Diseases

Restriction Endonuclease Products Market to hit new heights worth US$ 621.68 Million by 2031: Growth Plus Reports

PRESS RELEASE Published May 11, 2023 Newark, New Castle, USA Restriction Endonuclease Products Market Analysis 2023 | Business Opportunities, Pricing Strategy, Forthcoming opportunities planning, Market-specific challenges, Globally Market Key Facts are coverd in this report by Growth Plus Reports | 100+ Report Pages Restriction Endonuclease Products Market 2023 with 100+…

Continue Reading Restriction Endonuclease Products Market to hit new heights worth US$ 621.68 Million by 2031: Growth Plus Reports

CytomX Therapeutics Reports First Quarter 2023 Financial Results and Provides Business Update

CytomX Therapeutics Inc. – Continued progress in Phase 1 dose escalation for CX-904 (EGFRxCD3) – – IND enabling activities on track for filings for CX-2051 (EpCAM-directed ADC) and CX-801 (Interferon alpha-2b) in the second half of 2023 – – Bristol Myers Squibb advances Anti-CTLA-4 non-fucosylated Probody®, BMS-986288, from Phase 1…

Continue Reading CytomX Therapeutics Reports First Quarter 2023 Financial Results and Provides Business Update

Akero Therapeutics: Excellent Data, Solid Potential, No Near Term Catalysts

Ekaterina Dorozhkina/iStock via Getty Images I covered Akero (NASDAQ:AKRO) many times before and bought some shares two years ago which has done very well for me. I took profits twice, and am holding onto a bunch of shares for the long run, expecting more from the company and its lead…

Continue Reading Akero Therapeutics: Excellent Data, Solid Potential, No Near Term Catalysts

The Global Biotechnology Market in 2021 value stood at an estimated $1030.1 billion, and it will increase exponentially at a 14.3% CAGR between 2021 and 2030.

PRESS RELEASE Published May 5, 2023 Factual Market Research has released a report on the global Biotechnology market, including historical and current growth prospects and trends from 2022-2030. The Report utilizes unique research techniques that combine primary and secondary research to comprehensively analyze the global Biotechnology market and draw conclusions…

Continue Reading The Global Biotechnology Market in 2021 value stood at an estimated $1030.1 billion, and it will increase exponentially at a 14.3% CAGR between 2021 and 2030.

Vera Therapeutics Appoints Kerry Cooper, M.D., as Senior Vice President of Medical Affairs

Vera Therapeutics Appoints Kerry Cooper, M.D., as Senior Vice President of Medical Affairs BRISBANE, Calif., May 04, 2023 (GLOBE NEWSWIRE) — Vera Therapeutics, Inc. (Nasdaq: VERA), a late-stage biotechnology company focused on developing and commercializing transformative treatments for patients with serious immunological disease, today announced the appointment of Kerry Cooper,…

Continue Reading Vera Therapeutics Appoints Kerry Cooper, M.D., as Senior Vice President of Medical Affairs

Cell and Gene Therapy Market Projected to Grow at a CAGR of 22.8% and Reach US$ 62.5 Billion by 2032

COVINA, Calif., May 3, 2023 /PRNewswire/ — According to Prophecy Market Insights “Cell and Gene Therapy Market accounted for US$ 13.0 billion in 2022 and is estimated to be US$ 62.5 billion by 2032 and is anticipated to register a CAGR of 22.8%.” What is the Overview of Cell and Gene Therapy…

Continue Reading Cell and Gene Therapy Market Projected to Grow at a CAGR of 22.8% and Reach US$ 62.5 Billion by 2032

Lilly stock obesity therapy shows ~16% weight loss (NYSE:LLY)

jetcityimage/iStock Editorial via Getty Images Eli Lilly (NYSE:LLY) announced Thursday that its experimental weight loss therapy, tirzepatide, generated up to 15.7% of weight loss, and the company expects the FDA to decide on its approval as early as late 2023. Tirzepatide, a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1…

Continue Reading Lilly stock obesity therapy shows ~16% weight loss (NYSE:LLY)

Illumina (ILMN) Q1 Earnings Beat Estimates, Margins Contract

Illumina Inc. ILMN reported adjusted earnings per share (EPS) of 8 cents in the first quarter of 2023, sailing past the Zacks Consensus Estimate of 2 cents by a remarkable margin. However, the bottom line declined 92.5% from the year-ago quarter’s earnings of $1.07. The adjustments exclude the impact of GRAIL…

Continue Reading Illumina (ILMN) Q1 Earnings Beat Estimates, Margins Contract

CytomX Therapeutics to Present at the H.C. Wainwright BioConnect Investor Conference at NASDAQ

CytomX Therapeutics Inc. SOUTH SAN FRANCISCO, Calif., April 25, 2023 (GLOBE NEWSWIRE) — CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of conditionally activated, localized biologics, today announced that Sean McCarthy, D.Phil., chief executive officer and chairman, will present at the H.C. Wainwright BioConnect Investor Conference at NASDAQ…

Continue Reading CytomX Therapeutics to Present at the H.C. Wainwright BioConnect Investor Conference at NASDAQ

Diffuse Large B-Cell Lymphoma Pipeline Report Provides the Assessment of Mono and Combination Therapies by Stage

PRESS RELEASE Published April 24, 2023 DelveInsight’s, “Diffuse Large B-Cell Lymphoma Pipeline Insight 2023” report provides comprehensive insights about 80+ companies and 80+ pipeline drugs in the Diffuse Large B-Cell Lymphoma pipeline landscape. It covers the Diffuse Large B-Cell Lymphoma pipeline drug profiles, including Diffuse Large B-Cell Lymphoma clinical trials…

Continue Reading Diffuse Large B-Cell Lymphoma Pipeline Report Provides the Assessment of Mono and Combination Therapies by Stage

Cellular and Gene Therapy Product Market 2023 Analysis and Precise Outlook

PRESS RELEASE Published April 18, 2023 The global Cellular and Gene Therapy Product market research report published by market insight reports discovers the current outlook in global and key regions from the viewpoint of Major Players, Countries, Product Types, and end industries. This report studies top players in the global…

Continue Reading Cellular and Gene Therapy Product Market 2023 Analysis and Precise Outlook

Identifai-Genetics Closes a Post-Seed Fundraising Round of USD 3.3M; Dr. Susan Gross, former CMO at Natera, named as Chief Strategic Advisor

  Identifai offers unique, innovative solutions for the non-invasive detection of fetal genetic disorders, at an early stage of the pregnancy, using a risk-free blood test from the mother TEL AVIV, Israel, April 18, 2023 /PRNewswire/ — Identifai-Genetics, developer of unique AI-based solutions for non-invasive…

Continue Reading Identifai-Genetics Closes a Post-Seed Fundraising Round of USD 3.3M; Dr. Susan Gross, former CMO at Natera, named as Chief Strategic Advisor

Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

Design and synthesis of indolyl pyrimidinamine inhibitors of TTBK1/2 Our lead (AMG28, Fig. 1A) emerged from examination of the off-target activity of a published Amgen NF-κB inducing kinase (NIK) inhibitor27. The potency of AMG28 was reported in the MRC Kinase Profiling Inhibitor Database as 8% activity remaining for TTBK1 and 12%…

Continue Reading Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

Growing Investment in Biotechnology Research and Development

PRESS RELEASE Published April 11, 2023 The biotechnology market is a rapidly growing industry that combines biology, chemistry, and engineering to develop innovative products and services for a range of applications in healthcare, agriculture, food production, and the environment. Here are some key points about the biotechnology market: Key players:…

Continue Reading Growing Investment in Biotechnology Research and Development

Bigouden.Tv

Marché du traitement du lymphome non hodgkinien à cellules B, marché du traitement du lymphome non hodgkinien à cellules B 2028, industrie du traitement du lymphome non hodgkinien à cellules B, secteur du traitement du lymphome non hodgkinien à cellules B, traitement du lymphome non hodgkinien à cellules B PDF…

Continue Reading Bigouden.Tv

Will Bristol Myers (BMY) Gain From New Drugs’ Label Expansion?

Bristol-Myers Squibb BMY has recently been enjoying a string of positive regulatory updates. The company’s psoriasis drug Sotyktu (deucravacitinib) recently got approved by the European Commission (EC). Sotyktu is a first-in-class, selective tyrosine kinase 2 (TYK2) inhibitor for treating adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy,…

Continue Reading Will Bristol Myers (BMY) Gain From New Drugs’ Label Expansion?

Minimal residual disease monitoring in NSCLC

Background Cell-free DNA (cfDNA) refers to fragments of DNA released into the circulation by endothelial cells and white blood cells by active release or passively through apoptosis and necrosis.1,2 The fraction of cfDNA that originates from tumor is known as circulating tumor DNA (ctDNA). In 2016 the first commercial ctDNA…

Continue Reading Minimal residual disease monitoring in NSCLC

Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

Competing interests A.R. is a founder, equity owner, and consultant at Halo Solutions and has served as a consultant at Tyra Biosciences. J.F.G. has served as a compensated consultant or received honoraria from Bristol Myers Squibb, Genentech/Roche, Ariad/Takeda, Loxo/Lilly, Blueprint, Oncorus, Regeneron, Gilead, Moderna, Mirati, AstraZeneca, Pfizer, Novartis, iTeos, Nuvalent,…

Continue Reading Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

Illumina (ILMN) to Expand Genomics Capacity With New Pact

Illumina, Inc. ILMN recently collaborated with African Centre of Excellence for Genomics of Infectious Diseases (ACEGID) to develop a training academy. The collaboration is intended to increase Africa’s genomics capacity. The collaboration is built on the organizations’ shared goals to expand sequencing capabilities and capacity for all people in Africa….

Continue Reading Illumina (ILMN) to Expand Genomics Capacity With New Pact

Epithelial Ovarian Cancer Drugs Market Research Report Forecasted Data From 2023 To 2029

PRESS RELEASE Published April 5, 2023 Epithelial Ovarian Cancer Drugs market research is a report that is the result of careful investigation into relevant and useful data. The data that was examined took into account both existing top players and potential new competitors. Epithelial Ovarian Cancer Drugs the leading companies’…

Continue Reading Epithelial Ovarian Cancer Drugs Market Research Report Forecasted Data From 2023 To 2029

Abivax Appoints Marc de Garidel as Chief Executive Officer and Interim Board Chair

PRESS RELEASE Published April 5, 2023 Marc’s appointment bolsters Abivax’s position as a leader in the field of chronic inflammatory bowel diseases Corinna zur Bonsen-Thomas steps down as acting Chair and remains a Board Member Prof. Hartmut J. Ehrlich, M.D., retires from the CEO position PARIS, FRANCE / ACCESSWIRE /…

Continue Reading Abivax Appoints Marc de Garidel as Chief Executive Officer and Interim Board Chair

9 neuroscience biotech companies you should know about

Developing treatments for neurological diseases presents a huge challenge for neuroscience companies within the biotech industry. The central nervous system (CNS) is extremely complex and many neurological diseases can be difficult to treat due to the limited regenerative capacity of the CNS, and the fact that the blood-brain barrier –…

Continue Reading 9 neuroscience biotech companies you should know about

Sobi and Selecta Bio Gout Drug Hits Phase 3 Goals, Paving Way for FDA Submission

A gout drug that Swedish Orphan Biovitrim picked up in a $100 million deal has achieved the main goal in two Phase 3 studies, showing statistically significant reductions blood levels of the protein associated with the inflammatory condition. Based on those data, the company, which is more commonly referred to…

Continue Reading Sobi and Selecta Bio Gout Drug Hits Phase 3 Goals, Paving Way for FDA Submission

CytomX Therapeutics to Report Fourth Quarter and Full Year 2022 Financial Results on March 27, 2023

CytomX Therapeutics Inc. SOUTH SAN FRANCISCO, Calif., March 22, 2023 (GLOBE NEWSWIRE) — CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of conditionally activated, localized biologics, today announced that it will report full year 2022 financial results on Monday, March 27, 2023, after the close of U.S. markets. Following…

Continue Reading CytomX Therapeutics to Report Fourth Quarter and Full Year 2022 Financial Results on March 27, 2023

CytomX Therapeutics Reports Full Year 2022 Financial Results and Provides Business Update

CytomX Therapeutics Reports Full Year 2022 Financial Results and Provides Business Update – Internal focus on next generation therapeutic pipeline including ongoing Phase 1 for CX-904 (EGFRxCD3) and anticipated IND filings for CX-2051 (EpCAM-directed ADC) and CX-801 (Interferon alpha-2b) in the second half of 2023 – – Bristol Myers Squibb…

Continue Reading CytomX Therapeutics Reports Full Year 2022 Financial Results and Provides Business Update

CytomX Therapeutics Reports Full Year 2022 Financial

– Internal focus on next generation therapeutic pipeline including ongoing Phase 1 for CX-904 (EGFRxCD3) and anticipated IND filings for CX-2051 (EpCAM-directed ADC) and CX-801 (Interferon alpha-2b) in the second half of 2023 – – Bristol Myers Squibb advances Anti-CTLA-4 non-fucosylated Probody®, BMS-986288, from Phase 1 to Phase 2 clinical…

Continue Reading CytomX Therapeutics Reports Full Year 2022 Financial

NVIDIA Unveils Large Language Models and Generative AI Service to Advance Life Sciences R&D

Part of NVIDIA AI Foundations, New BioNeMo Cloud Service Accelerates Life Sciences Research, Drug Discovery and Protein Engineering; Amgen and a Dozen Startups Among Early Access Customers GTC—NVIDIA today announced an expanded set of generative AI cloud services for customizing AI foundation models to accelerate the creation of new proteins…

Continue Reading NVIDIA Unveils Large Language Models and Generative AI Service to Advance Life Sciences R&D

Cancer vaccine research may have reached ‘tipping point’

March 22, 2023 10 min read Source/Disclosures Published by: Disclosures: Disis reports being a stockholder/founder of EpiThany; grants from Aston Sci. and Bavarian Nordic during the conduct of the breast cancer vaccine study; serving as editor of JAMA Oncology outside the submitted work; and royalties for a…

Continue Reading Cancer vaccine research may have reached ‘tipping point’

Nvidia CEO Jensen Huang bolsters AI business at GTC

Nvidia Chief Executive Officer Jensen Huang has made several announcements at GTC, one of the top AI events for software developers. GTC: The Premier AI Conference GTC, in its 14th year, has become one of the world’s important AI gatherings. This week’s conference features 650 talks from leaders such as Demis…

Continue Reading Nvidia CEO Jensen Huang bolsters AI business at GTC

Nvidia aims to bring AI to every industry

ChatGPT is just the start of a rapid uptake of artificial intelligence (AI) across the board. With computing now advancing at what he called “lightspeed,” Nvidia founder and CEO Jensen Huang has announced a broad set of partnerships with Google, Microsoft, Oracle and a range of leading businesses that bring…

Continue Reading Nvidia aims to bring AI to every industry

Intravenous ravulizumab in mechanically ventilated patients hospitalised with severe COVID-19: a phase 3, multicentre, open-label, randomised controlled trial

Introduction Case fatality rates of COVID-19 have decreased globally from 3·7% in March, 2020, to 1·0% in February, 2023, due in part to vaccination, changes in the prevailing SARS-CoV-2 variant, and improvements in clinical care. 1 Global case fatality rate from COVID-19 has decreased by 96·8% during 2·5 years of…

Continue Reading Intravenous ravulizumab in mechanically ventilated patients hospitalised with severe COVID-19: a phase 3, multicentre, open-label, randomised controlled trial

PD-1 inhibitors in the treatment of gastric carcinoma

Introduction Though prevalence and mortality have been declining over the last 50 years, stomach cancer remains the fifth–most frequently diagnosed and fourth-leading cause of cancer-related death globally, accounting for over 1 million new cases and 769,000 deaths globally in 2020.1 Esophageal cancer follows closely behind, ranking seventh in terms of…

Continue Reading PD-1 inhibitors in the treatment of gastric carcinoma

Illumina (ILMN) Unveils Complete Long Reads Technology

Illumina, Inc. ILMN recently launched its first product based on its novel Illumina Complete Long Read technology. The high-performance, long-read, human whole-genome sequencing (WGS) assay – Illumina Complete Long Read is well-suited with Illumina NovaSeq X Plus, NovaSeq X, and NovaSeq 6000 Sequencing Systems. More on the News Illumina’s Complete…

Continue Reading Illumina (ILMN) Unveils Complete Long Reads Technology

Illumina (ILMN) Unveils Complete Long Reads Technology – March 15, 2023

Illumina, Inc. (ILMN Quick QuoteILMN – Free Report) recently launched its first product based on its novel Illumina Complete Long Read technology. The high-performance, long-read, human whole-genome sequencing (WGS) assay – Illumina Complete Long Read is well-suited with Illumina NovaSeq X Plus, NovaSeq X, and NovaSeq 6000 Sequencing Systems. More…

Continue Reading Illumina (ILMN) Unveils Complete Long Reads Technology – March 15, 2023

The Global Diffuse Large B-Cell Lymphoma (DLBCL) Therapeutics Market is forecast to grow by $ 2061.88 mn during 2022-2027, accelerating at a CAGR of 7.96% during the forecast period

NEW YORK, March 15, 2023 /PRNewswire/ — Global Diffuse Large B-Cell Lymphoma (DLBCL) Therapeutics Market 2023-2027 Source: ReportLinker The analyst has been monitoring the diffuse large B-Cell Lymphoma (DLBCL) therapeutics market and is forecast to grow by $ 2061.88 mn during 2022-2027, accelerating at a CAGR of 7.96% during the…

Continue Reading The Global Diffuse Large B-Cell Lymphoma (DLBCL) Therapeutics Market is forecast to grow by $ 2061.88 mn during 2022-2027, accelerating at a CAGR of 7.96% during the forecast period

ADC Therapeutics : Annual Report – Form 6-K

ADC Therapeutics SA 2022 Annual Report Table of Contents Letter to Shareholders Business Update Financial Review Corporate Governance Report from the Auditor on the Consolidated IFRS Financial Statements Consolidated IFRS Financial Statements for the Year Ended December 31, 2022 Report from the Auditor on the Statutory Financial Statements of ADC…

Continue Reading ADC Therapeutics : Annual Report – Form 6-K

Bridging the Gap to Reach Treatment Goals in DLBCL

CE Activity Release Date: March 15, 2023CE Activity Expiration Date: February 28, 2024 Time to Complete activity: 1 hour ACTIVITY DESCRIPTION Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, which typically occurs in patients over the age of 60 years. While chemoimmunotherapy (R-CHOP) has been…

Continue Reading Bridging the Gap to Reach Treatment Goals in DLBCL

Recombinant DNA Technology Market Expected to Reach USD 127.3 Billion by 2028: Verified Market Research

The market report is a good combination of qualitative and quantitative data that highlights significant market changes, obstacles that business and the competition must overcome, as well as new possibilities and trends in the Recombinant DNA Technology Market. JERSEY CITY, N.J. , March 13, 2023 /PRNewswire/ — The global Recombinant DNA…

Continue Reading Recombinant DNA Technology Market Expected to Reach USD 127.3 Billion by 2028: Verified Market Research

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK Nilufer Rahmioglu, Michal Krassowski, Cecilia S. K. Cheuk, Cecilia M. Lindgren, Anne Ndungu & Krina T. Zondervan Oxford Endometriosis CaRe Centre, Nuffield Department of Women’s and Reproductive Health, John Radcliffe Hospital, University of Oxford, Oxford, UK Nilufer Rahmioglu, Michal Krassowski, Danielle Perro, Nura F. Topbas-Selcuki, Cecilia S. K. Cheuk, Stephen H….

Continue Reading The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

The Global BCL-2 (B-cell lymphoma 2) Inhibitors Market is forecast to grow by $1,657.08 mn during 2022-2027, accelerating at a CAGR of 12.92% during the forecast period

ReportLinker Global BCL-2 (B-cell Lymphoma 2) Inhibitors Market 2023-2027. The analyst has been monitoring the BCL-2 (B-cell Lymphoma 2) inhibitors market and is forecast to grow by $1,657.08 mn during 2022-2027, accelerating at a CAGR of 12.92% during the forecast period. New York, March 13, 2023 (GLOBE NEWSWIRE) — Reportlinker.com

Continue Reading The Global BCL-2 (B-cell lymphoma 2) Inhibitors Market is forecast to grow by $1,657.08 mn during 2022-2027, accelerating at a CAGR of 12.92% during the forecast period

Diffuse large B-cell lymphoma (DLBCL) therapeutics market size to increase by USD 2,061.88 million between 2022 and 2027; Growth driven by increasing approval of therapeutics – Technavio | PR Newswire

NEW YORK, March 10, 2023 /PRNewswire/ — The diffuse large B-cell lymphoma (DLBCL) therapeutics market size is forecast to grow by USD 2,061.88 million between 2022 and 2027, and the growth momentum will accelerate at a CAGR of 7.96% during the forecast period. The number of regulatory approvals for therapeutics…

Continue Reading Diffuse large B-cell lymphoma (DLBCL) therapeutics market size to increase by USD 2,061.88 million between 2022 and 2027; Growth driven by increasing approval of therapeutics – Technavio | PR Newswire

Diffuse large B-cell lymphoma (DLBCL) therapeutics market size to increase by USD 2,061.88 million between 2022 and 2027; Growth driven by increasing approval of therapeutics

NEW YORK, March 10, 2023 /PRNewswire/ — The diffuse large B-cell lymphoma (DLBCL) therapeutics market size is forecast to grow by USD 2,061.88 million between 2022 and 2027, and the growth momentum will accelerate at a CAGR of 7.96% during the forecast period. The number of regulatory approvals for therapeutics…

Continue Reading Diffuse large B-cell lymphoma (DLBCL) therapeutics market size to increase by USD 2,061.88 million between 2022 and 2027; Growth driven by increasing approval of therapeutics

Prognostic landscape of mitochondrial genome in myelodysplastic syndrome after stem-cell transplantation | Journal of Hematology & Oncology

Jing Dong is supported by the Medical College of Wisconsin Cancer Center. N00014-17-1-2850 from the Office of Naval Research. The CIBMTR is supported primarily by Public Health Service U24CA076518 from the National Cancer Institute (NCI), the National Heart, Lung and Blood Institute (NHLBI) and the National Institute of Allergy and…

Continue Reading Prognostic landscape of mitochondrial genome in myelodysplastic syndrome after stem-cell transplantation | Journal of Hematology & Oncology

Relapse timing is associated with distinct evolutionary dynamics in DLBCL

Abstract Diffuse large B-cell lymphoma (DLBCL) is cured in over 60% of patients, but outcomes are poor for patients with relapsed or refractory disease (rrDLBCL). Here, we performed whole genome/exome sequencing (WGS/WES) on tumors from 73 serially-biopsied patients with rrDLBCL. Based on the observation that outcomes to salvage therapy/autologous stem…

Continue Reading Relapse timing is associated with distinct evolutionary dynamics in DLBCL

Research Scientist/Senior Research Scientist, General Bioinformatics – South San Francisco

IDEAYA Biosciences (NASDAQ: IDYA) is a public, clinical-stage synthetic lethality-focused precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics. Our approach integrates extensive capabilities in identifying and validating translational biomarkers with small molecule drug discovery…

Continue Reading Research Scientist/Senior Research Scientist, General Bioinformatics – South San Francisco

Health-related quality of life with pembrolizumab or placebo plus chemotherapy with or without bevacizumab for persistent, recurrent, or metastatic cervical cancer (KEYNOTE-826): a randomised, double-blind, placebo-controlled, phase 3 trial

Summary Background In the KEYNOTE-826 study, the addition of the anti-PD-1 monoclonal antibody pembrolizumab to chemotherapy with or without bevacizumab improved overall survival and progression-free survival (primary endpoints) versus placebo plus chemotherapy with or without bevacizumab, with manageable toxicity, in patients with persistent, recurrent, or metastatic cervical cancer. In this…

Continue Reading Health-related quality of life with pembrolizumab or placebo plus chemotherapy with or without bevacizumab for persistent, recurrent, or metastatic cervical cancer (KEYNOTE-826): a randomised, double-blind, placebo-controlled, phase 3 trial

7 rare autoimmune diseases Biotechs are Fighting to Treat

While we mostly think of disease as being caused by bacteria or viruses, an illness can often occur when the body’s own defenses turn against itself. Here we’ll take a look at seven rare autoimmune diseases you may not have heard of and what biotechs are doing to treat them….

Continue Reading 7 rare autoimmune diseases Biotechs are Fighting to Treat

Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies

Results Patients in ELEVATE UC 52 were enrolled between June 13, 2019, and Jan 28, 2021. Patients in ELEVATE UC 12 were enrolled between Sept 15, 2020, and Aug 12, 2021. ELEVATE UC 52 and ELEVATE UC 12 screened 821 patients and 606 patients, respectively, with 433 and 354 subsequently…

Continue Reading Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies

Relay Therapeutics: It Could Be Time To ‘Be Greedy When Others Are Fearful’ (NASDAQ:RLAY)

domoyega/E+ via Getty Images Investment Overview – Cash Intensive But Cash Rich – At Current Price Relay Offers The Patient Investor Value I have covered Relay Therapeutics (NASDAQ:RLAY) several times for Seeking Alpha since the company completed what was, at the time, the third largest biotech IPO in history, raising…

Continue Reading Relay Therapeutics: It Could Be Time To ‘Be Greedy When Others Are Fearful’ (NASDAQ:RLAY)

NVIDIA GTC 2023 to Feature Latest Advances in AI Computing Systems, Generative AI, Industrial Metaverse, Robotics; Keynote by Jensen Huang; Talks by OpenAI, DeepMind Founders

Virtual Conference to Offer 650+ Sessions From Leaders in Technology, Business, Academia and Government, March 20-23 NVIDIA today announced that company founder and CEO Jensen Huang will deliver the opening keynote at GTC 2023, covering the latest advancements in generative AI, the metaverse, large language models, robotics, cloud computing and…

Continue Reading NVIDIA GTC 2023 to Feature Latest Advances in AI Computing Systems, Generative AI, Industrial Metaverse, Robotics; Keynote by Jensen Huang; Talks by OpenAI, DeepMind Founders

Engineering protein glycosylation in CHO cells to be highly similar to murine host cells

1 Introduction Recombinant therapeutic proteins, also known as biologics, have been successfully used to treat a wide range of diseases, including cancers, inflammatory disorders, and cardiovascular diseases (Walsh, 2018). Biosimilars with comparable efficacy and safety profiles have emerged as alternative options to innovator therapies. A biosimilar is a biologic that…

Continue Reading Engineering protein glycosylation in CHO cells to be highly similar to murine host cells

Global DNA-Encoded Libraries Platforms And Services Market

DNA-encoded libraries (DELs) are a collection of small molecules that are attached to unique DNA sequences. These libraries can be used in drug discovery and development to screen for potential drug candidates. The DNA-encoded libraries platforms and services market is driven by the increasing demand for efficient and effective drug…

Continue Reading Global DNA-Encoded Libraries Platforms And Services Market

Phase 3 study shows zavegepant can relieve migraine pain quickly

[Zavegepant image from PubChem] The Lancet has published Phase 3 study results for zavegepant, an investigational nasal spray for the acute treatment of migraine. The study found that a single 10 mg intranasal dose of zavegepant was more effective than placebo for pain relief and freedom from the most bothersome symptom…

Continue Reading Phase 3 study shows zavegepant can relieve migraine pain quickly

Ligand’s Partner Travere Therapeutics Announces FDA Accelerated Approval of FILSPARI(TM) (sparsentan), the First and Only Non-immunosuppressive Therapy for the Reduction of Proteinuria in IgA Nephropathy

Ligand’s Partner Travere Therapeutics Announces FDA Accelerated Approval of FILSPARI™ (sparsentan), the First and Only Non-immunosuppressive Therapy for the Reduction of Proteinuria in IgA Nephropathy First single molecule Dual Endothelin Angiotensin Receptor Antagonist (DEARA) approved for use in patients with IgA nephropathy (IgAN) Interim results from the ongoing Phase 3…

Continue Reading Ligand’s Partner Travere Therapeutics Announces FDA Accelerated Approval of FILSPARI(TM) (sparsentan), the First and Only Non-immunosuppressive Therapy for the Reduction of Proteinuria in IgA Nephropathy

Phase 3 trial of pembrolizumab for prostate cancer misses endpoints

February 17, 2023 2 min read Source/Disclosures Published by: Source: Petrylak DP, et al. Abstract 19. Presented at: ASCO Genitourinary Cancers Symposium; Feb. 16-18, 2023; San Francisco. Disclosures: Petrylak reports research funding to his institution from, consulting/advisory roles or providing expert testimony to Amgen, Astellas Pharma, AstraZeneca,…

Continue Reading Phase 3 trial of pembrolizumab for prostate cancer misses endpoints

Phase 3 ZUMA-3 Study of Brexu-cel Elicits Survival Benefit in Relapsed/Refractory B-cell ALL

Findings from subgroup analyses of the phase 3 ZUMA-3 trial (NCT02614066) revealed that treatment with brexucabtagene autoleucel (brexu-cel; Tecartus) generated a survival benefit in patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL), regardless of prior lines of treatment, exposure to blinatumomab (Blincyto), or exposure to allogeneic stem cell transplant (alloSCT).1…

Continue Reading Phase 3 ZUMA-3 Study of Brexu-cel Elicits Survival Benefit in Relapsed/Refractory B-cell ALL

Who are the leading innovators in DNA polymerase compositions for the pharmaceutical industry?

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have…

Continue Reading Who are the leading innovators in DNA polymerase compositions for the pharmaceutical industry?

Hexagon Bio Raises $77.3 Million Series B Financing and Strengthens Leadership to Expand Novel Computational Discovery Platform and Advance Microbial Genome-Derived Small Molecules

Hexagon’s interdisciplinary platform enables broad opportunities across multiple therapeutic areas; company initially focused on oncology and infectious diseases Tara Arvedson, Ph.D., former Executive Director of Oncology Research at Amgen, who joined Hexagon last year as SVP, Research, has been promoted to Chief Scientific Officer Victor Cee, Ph.D., former research project…

Continue Reading Hexagon Bio Raises $77.3 Million Series B Financing and Strengthens Leadership to Expand Novel Computational Discovery Platform and Advance Microbial Genome-Derived Small Molecules

Hexagon Bio Closes $77.3M Series B Financing Round

NEW YORK – Hexagon Bio said Monday that it has closed a $77.3 million Series B round of venture investment. Previous investors the Column Group, Two Sigma Ventures, 8VC, and Nextech participated, as did new investor Canada Pension Plan Investment Board (CPP Investments) and several other unnamed financial backers. The…

Continue Reading Hexagon Bio Closes $77.3M Series B Financing Round

Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial

Background Sotorasib is a specific, irreversible inhibitor of the GTPase protein, KRASG12C. We compared the efficacy and safety of sotorasib with a standard-of-care treatment in patients with non-small-cell lung cancer (NSCLC) with the KRASG12C mutation who had been previously treated with other anticancer drugs. Methods We conducted a randomised, open-label…

Continue Reading Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial

Alternative to Lenalidomide ID’d for Maintenance in Multiple Myeloma – Consumer Health News

WEDNESDAY, Feb. 1, 2023 (HealthDay News) — For patients with newly diagnosed multiple myeloma after induction treatment and autologous stem cell transplantation, maintenance therapy with carfilzomib, lenalidomide, and dexamethasone may be better than lenalidomide alone, according to a study published online Jan. 12 in The Lancet Oncology. Dominik Dytfeld, M.D.,…

Continue Reading Alternative to Lenalidomide ID’d for Maintenance in Multiple Myeloma – Consumer Health News

The $100 genome: What breaking this accessibility barrier means for the future of genetic testing

Cheaper sequencing will also aid researchers working on diseases which have traditionally been underfunded. Bamshad cites cystic fibrosis, a condition which affects around 40,000 children and adults in the U.S., as one particularly pertinent example. “Funds for gene discovery for rare diseases are very limited,” he says. “We’re one of…

Continue Reading The $100 genome: What breaking this accessibility barrier means for the future of genetic testing

Bristol Myers Squibb Announces Positive CHMP Opinion for Once-Daily Sotyktu (deucravacitinib) as a Treatment for Adults With Moderate-to-Severe Plaque Psoriasis

PRINCETON, N.J.–(BUSINESS WIRE)–Bristol Myers Squibb (NYSE: BMY) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency has recommended the approval of Sotyktu (deucravacitinib) for the treatment of adults with moderate-to-severe plaque psoriasis. Sotyktu, an oral medication taken once-daily, is a first-in-class, selective,…

Continue Reading Bristol Myers Squibb Announces Positive CHMP Opinion for Once-Daily Sotyktu (deucravacitinib) as a Treatment for Adults With Moderate-to-Severe Plaque Psoriasis

Amgen, Illumina, and Nashville Biosciences Announce Genome Sequencing Agreement

deCODE genetics, a subsidiary of Amgen, will whole-genome sequence 35,000 African-American samples provided by Illumina and Nashville Biosciences. Illumina, a DNA sequencing and array-based technologies provider, and Nashville Biosciences, a subsidiary of Vanderbilt University Medical Center (VUMC), have teamed up with Amgen to provide whole-genome sequencing of approximately 35,000 DNA…

Continue Reading Amgen, Illumina, and Nashville Biosciences Announce Genome Sequencing Agreement

AstraZeneca eagerness for CinCor revealed in larger first offer

AstraZeneca kicked off this year’s J.P.Morgan Healthcare Conference in style, announcing a $1.8 billion deal that gave it ownership of CinCor Pharma and its mid-phase hypertension drug baxdrostat. But while Fierce Biotech reported at the time that AstraZeneca was able to exploit CinCor’s deflated share price, that was only part…

Continue Reading AstraZeneca eagerness for CinCor revealed in larger first offer

A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens

Abstract The ability to map genetic interactions has been essential for determining gene function and defining biological pathways. Therefore, a system to readily perform genome-wide genetic modifier screens in human cells is a powerful platform for dissecting complex processes in mammalian cells, where redundancy and adaptation commonly mask the phenotype…

Continue Reading A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens

The Accept Phase Ib/II Single Arm Study

Oral and Poster Abstracts 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Poster III Research, clinical trials, Lymphomas, Clinical Research, Combination therapy, Diseases, aggressive lymphoma, Therapies, Lymphoid Malignancies Andrew J Davies, BSc, BM, FRCP, PhD1,2*, Josh Caddy, BSc3*, Katy McLaughlin, BSc3*, Christopher Wignall, MSc3*, Robert…

Continue Reading The Accept Phase Ib/II Single Arm Study

Regeneron Files Amicus Brief in Support of CVC and Reversal in Interference No. 106,115* | McDonnell Boehnen Hulbert & Berghoff LLP

Biotechnology company Regeneron Pharmaceuticals, Inc. filed an amicus curiae brief at the Federal Circuit in support of the appeal by Junior Party the University of California/Berkeley, the University of Vienna, and Emmanuelle Charpentier (collectively, “CVC”) of the Patent Trial and Appeal Board’s decision to award priority to Broad Institute, Harvard University,…

Continue Reading Regeneron Files Amicus Brief in Support of CVC and Reversal in Interference No. 106,115* | McDonnell Boehnen Hulbert & Berghoff LLP

CVC Files Appeal Brief in Interference No. 106,115 | McDonnell Boehnen Hulbert & Berghoff LLP

The Patent Trial and Appeal Board (like its predecessor, the Board of Patent Appeals and Interferences or BPAI) occasionally renders an opinion having the tendency to raise an eyebrow or two, which on occasion has led the Federal Circuit, like its predecessor the Court of Claims and Patent Appeals, to…

Continue Reading CVC Files Appeal Brief in Interference No. 106,115 | McDonnell Boehnen Hulbert & Berghoff LLP

Restriction Endonucleases Products (REP) Market Business Overview and Global Development Trends

Global Restriction Endonucleases Products (REP) Market: Overview The leading applications for the products and solutions offered by the manufacturers and players functional in the landscape of the global restriction endonucleases products (REP) market include epigenetics, fragment length polymorphism or RFLP, cloning, sequencing, polymerase chain reaction, and restriction digestion, among others….

Continue Reading Restriction Endonucleases Products (REP) Market Business Overview and Global Development Trends

Global Fibroblast Growth Factor Receptor 2 market key industry players and their market scope 2022

Pune, Maharashtra, India, September 22 2022 (Wiredrelease) Marke.biz–:The research provides the Global Fibroblast Growth Factor Receptor 2 Market aims at leveraging the insights and perspectives derived based on both qualitative and quantitative data evaluations for the forecast period, 2022-2030. The use of the technology for malady wipeout through direct correction of disturbances…

Continue Reading Global Fibroblast Growth Factor Receptor 2 market key industry players and their market scope 2022

Injectable Drugs Market Analysis of the Competitive Landscape, with a Forecast for 2027

Wilmington, Delaware, United States, Transparency Market Research Inc. – The global injectable drugs market is relied upon to enlist a strong double-digit CAGR within the forecast period from 2019 to 2027. The market is majorly classified on the basis of drug-class, geography, molecule-type, and application. From the previous one entire…

Continue Reading Injectable Drugs Market Analysis of the Competitive Landscape, with a Forecast for 2027

Amgen announces top-line results from biosimilar phase 3 study

Amgen has announced positive top-line results from its DAHLIA study. This was a randomized, double-blind, active-controlled, two-period crossover phase 3 study evaluating the efficacy and safety of ABP 959, a biosimilar candidate to SOLIRIS (eculizumab), compared with SOLIRIS in adult patients with paroxysmal nocturnal hemoglobinuria (PNH). Amgen said the study…

Continue Reading Amgen announces top-line results from biosimilar phase 3 study

CRISPR Gene Detection and Diagnostic Industry 2022 Market Size, Share and Growth, Global Segments Analysis and Dynamic Research Report 2029

The Wide Ranging CRISPR Gene Detection and Diagnostic Business Report encompasses a thorough study of current situation of the global market along with several market dynamics. The market research report is a demonstrated source of information which offers a telescopic view of the current market trends, size, share, growth, demand,…

Continue Reading CRISPR Gene Detection and Diagnostic Industry 2022 Market Size, Share and Growth, Global Segments Analysis and Dynamic Research Report 2029

Restriction Endonucleases Products (REP) Market: Overview, Major Trends & Regional Assessment

Global Restriction Endonucleases Products (REP) Market: Overview Albany NY, United States: The leading applications for the products and solutions offered by the manufacturers and players functional in the landscape of the global restriction endonucleases products market include epigenetics, fragment length polymorphism or RFLP, cloning, sequencing, polymerase chain reaction, and restriction…

Continue Reading Restriction Endonucleases Products (REP) Market: Overview, Major Trends & Regional Assessment

Top Trends Shaping the Global Biotechnology Industry in 2021

Global Biotechnology Market Analysis with forecast period 2020 to 2025 provides an in-depth analysis of market growth factors, future assessment, country-level analysis, Biotechnology industry distribution, and competitive landscape analysis of major industry players. The research report of global Biotechnology market report offers the extensive information about the top most makers…

Continue Reading Top Trends Shaping the Global Biotechnology Industry in 2021

New Results from BabySeq, Pharmacogenomic Updates, New Products

September 1, 2021 | Harvard-Israel and Sema4-Avera launch precision medicine partnerships, Rice announces new Genetic Design and Engineering Center, Foundation Medicine partners with Epic, and Amgen and USC provide cryo-TEMs. Plus new products from BioIVT, BD.   Pluto Biosciences has launched its cloud-based, collaborative life sciences platform that leverages technology…

Continue Reading New Results from BabySeq, Pharmacogenomic Updates, New Products