Category: Roche

Bioinformatics Software QA Engineer (Remote Option) at Genentech

The Position Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world’s most complex health challenges, we ask bigger questions that challenge our industry and…

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The Accept Phase Ib/II Single Arm Study

Oral and Poster Abstracts 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Poster III Research, clinical trials, Lymphomas, Clinical Research, Combination therapy, Diseases, aggressive lymphoma, Therapies, Lymphoid Malignancies Andrew J Davies, BSc, BM, FRCP, PhD1,2*, Josh Caddy, BSc3*, Katy McLaughlin, BSc3*, Christopher Wignall, MSc3*, Robert…

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Global DNA Sequencing Market strategy patterns and forecasts in the coming years 2033

Pune, Maharashtra, India, November 15 2022 (Wiredrelease) Mrfactors.com –:The Global DNA Sequencing Market is estimated to be USD 4581.2 million in 2022 and is expected to reach USD 16915.22 million by 2033, growing at a CAGR of 11.5%. DNA sequencing is the process of determining a DNA segment’s nucleotide sequence….

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Digital Genome Market Projected to Reach US$ 20,812.81 million in 2027

According to a new market research study of “Digital Genome Market to 2027 – Global Analysis and Forecast by Product, Application, and End User,” the global digital genome market is expected to reach US$ 20,812.81 million in 2027 from US$ 11,065.31 million in 2019. The market is estimated to grow…

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Simulated global warming affects endophytic bacterial and fungal communities of Antarctic pearlwort leaves and some bacterial isolates support plant growth at low temperatures

Sample collection Colobanthus quitensis samples were collected at King George Island near the Henryk Arctowski Polish Antarctic Station, Maritime Antarctica (62°14’ S, 58°48’ W) during the summer season (February 2018). Samples were collected inside the Antarctic Specially Protected Area (ASPA) 128 using permits provided by The Chilean Antarctic Institute (INACH)…

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Bioconductor – RTCA

Open-source toolkit to analyse data from xCELLigence System (RTCA) by Roche Bioconductor version: 2.5 Import, analyze and visualize data harvested from Roche(R) Xcelligence RTCA systems. The package imports the rich information in real-time cell electrical impedance data into computational and statistical environment R/Bioconductor. As an alternative to commercial software provided…

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Cellular glycan modification by B3GAT1 broadly restricts influenza virus infection

Ethics statement All procedures involving laboratory mice were approved by the Duke University IACUC under the protocol numbers A189-18-08 and A142-21-07. Mice were housed with up to five mice per cage and the ambient room conditions ranged from 70–74 °F and 30–70% humidity with a 12-hour dark/light cycle. Animals were assessed…

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Restriction Endonucleases Products (REP) Market Business Overview and Global Development Trends

Global Restriction Endonucleases Products (REP) Market: Overview The leading applications for the products and solutions offered by the manufacturers and players functional in the landscape of the global restriction endonucleases products (REP) market include epigenetics, fragment length polymorphism or RFLP, cloning, sequencing, polymerase chain reaction, and restriction digestion, among others….

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Evasion of cGAS and TRIM5 defines pandemic HIV

Cells and reagents HEK293T and U87 cells were maintained in DMEM medium (Gibco) supplemented with 10% fetal bovine serum (FBS, Labtech) and 100 U ml−1 penicillin plus 100 μg ml−1 streptomycin (Pen/Strep; Gibco). THP-1-IFIT1 cells that had been modified to express Gaussia luciferase under the control of the IFIT1 promoter were described previously62. THP-1…

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Inferring and perturbing cell fate regulomes in human brain organoids

Experimental methods Stem cell and organoid culture We used six human iPS cell lines (Hoik1, Wibj2, Kucg2 from the HipSci resource47; 409B2 from the RIKEN BRC cell bank; 01F49i-N-B7 (B7) from Institute of Molecular and Clinical Ophthalmology Basel; and WTC from the Allen Institute) and three human ES cell lines (H1-PAX6YFP…

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Universal Transfection Reagents: Improving Efficiency and Decreasing Cell Toxicity

Transfection alters the genetic makeup of eukaryotic cells by introducing foreign nucleic acids, including DNA, RNA, and small noncoding RNAs such as siRNA, shRNA, and miRNA. Scientists use transfection techniques to advance cellular research and enhance drug discovery by enabling researchers to characterize cellular processes and study molecular disease mechanisms.1–3 …

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Next Generation Sequencing (NGS) Market, Outlook Size Share Industry Segmentation, Targeting, Positioning Exclusive Report by |Quince Market Insights

Next Generation Sequencing (NGS) Market Scope The Next Generation Sequencing (NGS)-market size was assessed at USD in 2023. Developing number of organizations tapping the nearness Next Generation Sequencing (NGS) market, alongside expanding interests in the Next Generation Sequencing (NGS) Market innovation, is supposed to move the business development. expected to…

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Oligonucleotide Pool Library Market Incredible Possibilities, Growth Analysis and Forecast To 2028

The research literature of Oligonucleotide Pool Library market consists of vital information regarding the growth stimulants, challenges, and other prospects which are shaping the business trends over the period of 2022-2028. According to seasoned experts, the market is expected to exhibit a CAGR of XX% over the…

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Lymphoma, 2 out of 3 Italians know it but only 20% know the symptoms

There are over 150 thousand people affected by non-Hodgkin’s lymphoma in Italy. Two out of 3 Italians declare that they know lymphomas, 3% have had direct experience of them, but they have limited and superficial knowledge: only 20% recognize at least 3 symptoms. Diffuse large B-cell lymphoma (Dlbcl) is the…

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Epidemiology, genetic diversity, and association of canine circovirus infection in dogs with respiratory disease

Animal and ethics A total of 190 dogs, comprising both healthy dogs (n = 76) and dogs with respiratory symptoms (n = 114), were included in this study. The research assessed nasal swab (NS) and oropharyngeal swab (OS) collected between January and November 2020. The samples from the healthy group were collected from clinically…

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Cell-Free DNA Testing Market – Lord Web

Welcome to our community, we want you capitalize from Cell-Free DNA Testing Market and are fortunate to go to you web site, you possibly can succeed know-how tradition and craft on our web site 24 hours, we proffer you followers the most recent world advice across the clock . …

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A global dataset of microbial community in ticks from metagenome study

Data collection The study was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement20. To attain an exhaustive review of the published literature on the microbiome diversity by NGS in field-collected ticks, a literature search was conducted on Chinese and English databases using a set…

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SR. SCIENTIST, HUMAN GENETICS BIOINFORMATICS in San Francisco, CA for Genentech

Details Posted: 09-Sep-22 Location: San Francisco, California Type: Full Time Years of Experience: Less than 2 Join a Team that Lives to Improve Lives  People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology,…

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Global Gene Therapy R&D Market Worth US$ 22,685.70 million by 2031: Visiongain Reports Ltd

Visiongain Reports Ltd Global Gene Therapy R&D Market Forecast 2021-2031: – Market Segment by Disease {Cancer, Rare Diseases (Oncologic, Non-Oncologic), Cardiovascular Diseases, Ophthalmic Diseases, Hematology, Neurological, Diabetes Mellitus, Other Diseases}, Vector {Viral (Retrovirus, Adenovirus, AAV, Lentivirus, Others), Non-Viral (Naked DNA, Gene Gun, Electroporation, Lipofection)}, Techniques (Gene Augmentation Therapy, Gene Replacement…

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Bioinformatics Analysis of the Key Genes and Pathways in Multiple Myel

Introduction Multiple myeloma is a B-cell malignancy characterized by the malignant proliferation of clonal plasma cells in bone marrow,1 It is the second most common hematological malignancy after lymphoma.2 The age-standardised rate (ASR) of multiple myeloma incidence was 1·78 (95% UI 1·69-1·87) per 100 000 people globally and mortality was…

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Primary Anaplastic Lymphoma Kinase (ALK)-Negative Anaplastic Large Cell Lymphoma (ALCL) Presenting as Perforation Peritonitis: A Case Report and Management Principles

Anaplastic large cell lymphoma (ALCL) has a characteristic feature that distinguishes it from the other types of non-Hodgkin lymphomas (NHLs) – the presence of a marker on its surface called CD30. It can be either cutaneous, systemic, or around breast implants. The systemic type of ALCL can be further classified…

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DNA Methylation Sequencing market to showcase strong CAGR between 2028 and 2028

The business intelligence report on the DNA Methylation Sequencing market provides investors a tactical advantage by focusing on the growth trajectory of this business vertical during 2022–2028 through a thorough assessment of the historical and current trends. The estimations in the document have also been calculated and verified by professionals…

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Principal Software Engineer – Bioinformatics Job in Mississauga, Ontario – Hoffmann-La Roche Ltd

Impact HealthcareRoche Sequencing is not only changing science, but we are changing lives. Our software teams are laying the groundwork for the future by developing powerful bioinformatics algorithms, data analysis tools, and software/systems infrastructures so researchers and clinicians can make better health decisions faster. The path to curing cancer lies…

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DNA Sequencing and Next-Generation Sequencing Market will Grow

DNA Sequencing and Next-Generation Sequencing While producing DNA Sequencing and Next-Generation Sequencing market report, combination of best industry insight, practical solutions, talent solutions and latest technology have been utilized. The report aids in taking important decisions for the growth of business. What is more, with the utilization of best-practice models,…

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Genentech DLBCL treatment gets FDA approval

Genentech, a part of the Roche Group, says the U.S. Food and Drug Administration (FDA) has accepted the company’s supplemental Biologics License Application (sBLA) for Polivy. Polivy (polatuzumab vedotin-piiq), in combination with Rituxan (rituximab) plus cyclophosphamide, doxorubicin and prednisone (R-CHP) for the treatment of people with previously untreated diffuse large…

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Efficient genome editing in wild strains of mice using the i-GONAD method

Mice A laboratory strain B6 was purchased from CLEA Japan Inc. (Tokyo, Japan), while nine wild strains (BFM/2, BLG2, CHD, HMI, KJR, MSM, NJL, PGN2, and SWN) were bred at NIG (Shizuoka, Japan) (Table 1). All mice were maintained at the animal facility in NIG, under specific-pathogen-free conditions and controlled…

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Cancer vaccines for next generation are available for personal use

Through biomarkers and, increasingly, gene sequencing, we have seen significant advances in disease diagnosis. These advances have enhanced our ability to characterize diseases at the molecular level, and they allow us to uncover ever more subtle distinctions between cancerous cells and normal cells. This addition has prompted significant improvements in…

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Genotyping Market Analysis, Insights by Emerging Trends, Future Growth, Revenue Analysis, Demand

Genotyping is the process of studying DNA sequence to determine genetic constitution in the genotypes of living organisms, such as humans, plants, animals, and microorganisms. Human genotyping helps in determining fatherhood or motherhood. Genotyping of micro-organisms, including viruses and bacteria, helps in prevention of spreading of pathogens by tracking down…

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Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth

Cell culture Human glioblastoma cells (U87MG and U87MG-Luc) and human embryonic kidney cells (HEK293) were obtained from the American Type Culture Collection (Manassas, Va.). Cells were cultured in Dulbecco’s Modified Eagle Medium supplemented with 10% fetal bovine serum (Gibco™ Fetal Bovine Serum South America, Thermo Scientific Fisher-US), 2 mM l-glutamine, 50 U/ml…

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Senior Bioinformatics Scientist at Roche July, 2022

Position summary As a Senior Bioinformatics Scientist, you will provide bioinformatics support for product research and development, as well as the marketing, sales and on-market product support teams. You will collaborate and innovate with bioinformatics scientists, software engineers and  molecular biologists to build products that will impact patient care for…

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Investment Opportunity Analysis and Industry Share Forecast 2028

The Magnetic Bead Purification Kits market report provides detailed competitive landscape of the global market. It includes company, market share analysis, product portfolio of the major industry participants. The report provides detailed segmentation of the Global Magnetic Bead Purification Kits industry based on product segment,…

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Sequencing Driven Metagenomics Market Size, Share, Regional Growth Analysis, Upcoming Trends, R&D Status with Current and Future Industry Figures Research Report 2028

The comprehensive Sequencing Driven Metagenomics market survey report covers an array of factors that have an influence on the market and Sequencing Driven Metagenomics industry which includes industry insight and critical success factors (CSFs), market segmentation and value chain analysis, industry dynamics, drivers, restraints, key opportunities, technology and application outlook,…

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Tempest to Present at the Jeff

SOUTH SAN FRANCISCO, Calif., June 06, 2022 (GLOBE NEWSWIRE) — Tempest Therapeutics, Inc. ( TPST), a clinical-stage oncology company developing first-in-class1 therapeutics that combine both targeted and immune-mediated mechanisms, today announced that management will present at the Jefferies Healthcare Conference on Wednesday, June 8, 2022 at 10:30 a.m. ET. To…

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Sr. Research Associate, Bioinformatics job with F. Hoffmann-La Roche AG

The Bioinformatics Senior Research Associate is responsible for designing and troubleshooting PCR-based assays for use with the GenMark Dx ePlex platform. The ideal candidate must be able to work in a collaborative research and IVD product development environment and demonstrate ability to analyze sequence data to drive assay development. The…

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Frontiers | Serum and Serum Exosomal CircRNAs hsa_circ_0001492, hsa_circ_0001439, and hsa_circ_0000896 as Diagnostic Biomarkers for Lung Adenocarcinoma

Introduction Lung cancer is associated with high morbidity and mortality and continues to be a major public health problem worldwide (1). Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer. While the 5-year survival rates of patients with lung cancer are still <15%, rates are closer to…

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Metagenomic Sequencing Market Size And Forecast

New Jersey, United States – The Verified Market Reports released the latest competent intelligence market research report on the Metagenomic Sequencing Market, The report aims to provide a thorough and accurate analysis of the Metagenomic Sequencing market, taking into account market forecast, competitive intelligence, technical risks, innovations, and other pertinent data. Its…

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Antigen Detection Test Market See Huge Growth for New Normal

Antigen Detection Test Market research report is the new statistical data source added by Research Cognizance. “Antigen Detection Test Market is growing at a High CAGR during the forecast period 2022-2029. The increasing interest of the individuals in this industry is that the major reason for the expansion of this…

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Roche (RHHBY) Gets EC Approval for Polivy Combination in DLBCL – May 26, 2022

Roche (RHHBY Quick QuoteRHHBY – Free Report) recently announced that the European Commission (“EC”) has granted approval to lymphoma drug Polivy (polatuzumab vedotin) in combination with MabThera (rituximab) plus cyclophosphamide, doxorubicin and prednisone (R-CHP) for the treatment of adult patients with previously untreated diffuse large B-cell lymphoma (DLBCL). Polivy is…

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Bispecific antibodies | Scientist Live

Bispecific antibodies: rising stars in antibody therapeutics Monoclonal antibodies (mAbs) are important therapeutic agents for the treatment of many human diseases, such as cancer, autoimmune diseases, cardiovascular diseases, asthma, and viral infections. Unlike monospecific mAbs, bispecific antibodies (bsAbs) are antibodies containing two antigen-binding sites and therefore can simultaneously target two…

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Restriction Endonucleases Products (REP) Market: Overview, Major Trends & Regional Assessment

Global Restriction Endonucleases Products (REP) Market: Overview Albany NY, United States: The leading applications for the products and solutions offered by the manufacturers and players functional in the landscape of the global restriction endonucleases products market include epigenetics, fragment length polymorphism or RFLP, cloning, sequencing, polymerase chain reaction, and restriction…

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Global Nucleic Acid Labeling Market 2022 to 2028 Latest Innovations and Major Players are Merck & Co., Inc., PerkinElmer, Inc.

The global markets are being disrupted by the arrival of industry 4.0, which is accompanied by digitalization, automation, and artificial intelligence. Fundamental geopolitical shifts are changing global economic power centers. As a result, The Brainy Insights has launched a research study on the future of the global Nucleic Acid Labeling…

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Single-Cell Transcriptome Resource From Human Cell Atlas Team Yields Immune, Disease Insights

NEW YORK – A large international team came up with single-cell and single-nucleus transcriptomic resources to characterize the diverse cell types found in the human body, along with related gene expression and splicing features that offer clues to processes at play within and across tissues and organs. In a series…

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