Category: Research

Senior Bioinformatics Scientist II Job in California (CA), Bioinformatics Career, Jobs in Exact Sciences

Position Overview The Senior Bioinformatics Scientist II is largely self-driven, working in collaboration with others on one or more projects which are extremely complex in scope. The Senior Research Scientist II is responsible for successfully leading the planning and execution of projects. This position involves independently making detailed observations,…

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Experts urge caution over biotech that can wipe out insect pests

Credit: Unsplash/CC0 Public Domain Dozens of scientists, experts and campaigners called for a ban on the release of genetically-edited organisms into the wild, in a statement Friday warning of potentially severe risks to the world’s pollinators. The appeal was launched at crunch biodiversity talks in Montreal, where delegates from almost…

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Difference between Joint Dimensionality Reduction and Dimensionality Reduction ?

Difference between Joint Dimensionality Reduction and Dimensionality Reduction ? 1 Hi, I’m wondering a question: what is the difference between Joint Dimensionality Reduction (jDR) and Dimensionality Reduction ? Thank you for your answer 🙂 Dimensionality-reduction • 25 views Dimensionality reduction refers to various methods for transforming a high-dimensional space (i.e….

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Doctor administers vaccine to toddler in unique manner, viral video has 23 million views

New Delhi: For most children, going to the doctor’s clinic is a nightmare. Most children are terrified of bitter medicines, medical equipment, and, most importantly, injections. However, in this adorable video, a doctor goes above and beyond his duties and performs amazing techniques for giving vaccination shots to toddler. The…

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Applications of Electroporation in Microorganism Inactivation and Pain Remediation

   Electroporation uses puled electric fields to permeabilize cell membranes to either introduce exogeneous molecules into cells through normally impermeable membranes or completely lysing cells to induce cell death. This thesis examines electroporation in combination with a natural product for microorganism inactivation and pulsed magnetic fields for inducing pain remediation….

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Bioinformatics Programmer 4 (Hybrid) – 120485

UCSD Layoff from Career Appointment: Apply by 12/13/22 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor. Special Selection Applicants: Apply by 12/22/22. Eligible Special Selection clients should contact their Disability Counselor for assistance. This position will remain posted until a suitable candidate has been…

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Automation Software Engineer Jobs in Grenoble (38)

Automation Software Engineer Jobs in Grenoble (38) at European Molecular Biology Laboratory Title: Automation Software Engineer Company: European Molecular Biology Laboratory Location: Grenoble (38) Scientific Services and SupportGrenoble, France These are exciting times at EMBL Grenoble. We are looking to complete our development team with an enthusiastic automation software engineer….

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Left Join Issue in R

Left Join Issue in R 0 I want to merge two data frames (named ‘data’ and ‘add’) so that only the rows of the first dataframe(data) are kept (Left Join). When I use Merged <- merge(data, add, by.x = “DATAGene”, by.y = “ADDGene”, all.x = TRUE, all.y = FALSE) I…

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Experts urge vaccination as cases skyrocket in Dallas

Associated Press US sending $275 million in military aid to Ukraine The U.S. is sending an additional $275 million in military aid to Ukraine, including large amounts of ammunition and high-tech systems that can be used to detect and counter drones in its ongoing war with Russia,in its ongoing war…

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Faculty Positions in Biological Sciences, Immunology job with XIAN JIAOTONG LIVERPOOL UNIVERSITY (XJTLU)

School: School of Science Department: Biological Sciences Position: Faculty Positions in Biological Sciences_Immunology Location: Suzhou, China Contract Type: Fixed-term, renewable. 3rd contract is open-ended ABOUT XJTLU In 2006 Xi’an Jiaotong-Liverpool University (XJTLU) was created by the University of Liverpool and Xi’an Jiaotong University – a top ten university in China….

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Bioinformatics Analyst I job in Danville at Geisinger

Job Title Bioinformatics Analyst I Location Work from Home Job Category Information Technology Support Services Schedule Days Work Type Full time Department Research Bioinformatics Division Date posted 12/08/2022 Job ID R-41783 Job Summary Primary accountability is to leverage the organization’s data assets…

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Dr. Nicolau Receives 2022 Development Grant from American Neuromuscular Foundation

Newswise — Rochester, Minn. (December 08, 2022)- The American Neuromuscular Foundation (ANF), is excited to announce the 2022 Development Grant Recipient, Stefan Nicolau, MD, for his research project “CRISPR/Cas9 correction of a common Duchenne muscular dystrophy (DMD) deletion.” Dr. Nicolau is a research fellow at the Abigail Wexner Research Institute…

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Senior Network and Security Engineer job with European Molecular Biology Laboratory (EMBL)

The IT Services team operates and supports the IT infrastructure and services at EMBL headquarters in Heidelberg and at the laboratory’s sites in Barcelona and Rome. As part of IT Services, the Network and Security team is responsible for managing and developing the network infrastructure in our data centres, on…

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CNVKit does not output all the accessible regions in the targets bed file

CNVKit does not output all the accessible regions in the targets bed file 1 Hello everybody, I am using CNVkit on my data using hg38 as reference. The command that I am using is the following: cnvkit.py batch sample.bam -n control.bam -m wgs -f reference.fasta –target-avg-size 1000 –output-dir results/ So,…

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Things You Need to Know About the mRNA Vaccine

mRNA is a molecule that carries information from DNA to the ribosome. It is a single strand of RNA, meaning it has only one base pair per nucleotide instead of the four or more in DNA. The translation process starts with a Shine-Dalgarno sequence recognition sequence on each side of…

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Postdoc in data science, bioinformatics or computational biology in microbiome Novo Nordisk Foundation Center for Basic Metabolic Research

University of Copenhagen The University of Copenhagen is seeking up to two highly motivated and talented postdoctoral fellows to commence on March 1, 2023, or after agreement at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen. About UsThe Novo Nordisk Foundation Center for Basic Metabolic Research’s…

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Liberate Bio is Bringing Precision Delivery to Genetic Medicines

The development of efficient delivery technologies has lagged behind significant advancements in nucleic acid therapeutics, such as antisense oligonucleotids (ASOs), short interfering RNA (siRNA), mRNA therapeutics, and genome editors. There must be a renaissance in genetic medicine delivery for these strategies to realize their full potential. Increasingly, the greatest hope…

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SNPs in LD with fine-mapped SNPs, are they equally likely to be causative?

SNPs in LD with fine-mapped SNPs, are they equally likely to be causative? 0 I am trying to perform a post-GWAS functional analysis of disease from fine-mapped SNPs, and then calculate SNPs in LD with these fine-mapped SNPs. Since statistical fine-mapping methods of GWAS SNPs were able to prioritize a…

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ExPLoRNA Therapeutics receives funding to advance its novel mRNA technology | DNA RNA and Cells

ExPLoRNA Therapeutics receives funding to advance its novel mRNA technology Details Category: DNA RNA and Cells Published on Wednesday, 07 December 2022 17:28 Hits: 199 Funding from the Bill & Melinda Gates Foundation will go toward understanding the benefits of novel cap analogs for therapeutic applications WARSAW, Poland I…

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Shriners Children’s hiring Bioinformatics Scientist (Hybrid) in Tampa, Florida, United States

Shriners Children’s is a family that respects, supports, and values each other. We are engaged in providing excellence in patient care, embracing multi-disciplinary education, and research with global impact. We foster a learning environment that values evidenced based practice, experience, innovation, and critical thinking. Our compassion, integrity, accountability, and resilience…

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Vice President, Biometrics – United States – CRO job with Global Life Science Hub

Job Description The Global Life Science Hub has entered into an exclusive partnership with an up-and-coming, niche full-service Contract Research Organisation specialising in Rare Oncology diseases. This company of 300 employees globally are partnered with some of the most unique and ground-breaking Biotech companies known in the industry. With a…

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Leveraging Modern Electronics to Streamline CRISPR Workflows

By Kiana Aran, PhD The adoption of CRISPR-Cas systems in therapeutics development has led to the rapid emergence of several clinical candidates for treating rare and challenging diseases, including sickle-cell anemia, β-thalassemia, Duchenne muscular dystrophy, and ocular diseases. Translation into the clinic has been facilitated by a robust preclinical framework…

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Any good tools for biological annotation of ChIP-seq broadpeak (H3K9me3, H3K27me3)?

Any good tools for biological annotation of ChIP-seq broadpeak (H3K9me3, H3K27me3)? 0 Hi, I have called ChIP-seq broadpeak (H3K9me3, H3K27me3) using SICER2 in mm10. The peak looks good and consistent with the IGV findings. Is there any good tools to annotate these broad peaks to coding genes? I know GREAT(great.stanford.edu/public/html/)…

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Touchlight and Odimma Therapeutics Announce Clinical Material Supply Agreement to Develop Personalised Cancer Therapy Utilising Doggybone DNA

HAMPTON, England–(BUSINESS WIRE)–Touchlight, a biotechnology company pioneering enzymatic DNA production to enable genetic medicines, today announces a development and supply agreement with Odimma Therapeutics, a French biotech company focusing on personalised cancer immunotherapy. The agreement focuses on the provision of clinical material for use in Odimma’s oncological neoantigen program. Through…

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Research Fellow, Smart Robots job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description Postdoctoral Fellows and Research Fellow needed to establish the NUS Lab of Prof Gregory S. Chirikjian. Multiple positions available to do mathematical modelling, computer programming, and robot hardware work. Qualifications PhD in Mechanical Engineering, Computer Science, Mathematics or Physics. Knowledge and experience in one or more…

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Lecturer / Associate Professor (Biostatistics), Curtin Medical School job with CURTIN UNIVERSITY

$125,937-166,536 (ALC/D) plus 17% superannuation 4-year fixed contract, full-time role Based within the Curtin Medical School Your new role We have an exciting opportunity for a senior biostatistician or bioinformatics expert experienced in analysing medical related data to work for Curtin University on a full-time basis….

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‘Genetics May Help Humans Live A Long Life’

From a south Kashmir school to Canada’s Laval University, Dr Abdul Wajid has dedicated his research career to a better understanding of genes. To his credit is the discovery of a novel role of protein, Kinase CK2 in chromatin modulating processes. Currently heading a vertical at the University of Kashmir’s…

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Different results in finding human sequences from metagenomes (bowtie2 and Kraken2)

Different results in finding human sequences from metagenomes (bowtie2 and Kraken2) 0 I’d like to remove human reads from human gut metagenomes. Many studies conduct bowtie2 to human genome and retain only unmapped reads. I did so, but many reads that did not mapped to human genome were annotated as…

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Vaccination helped India’s transition from reactive to proactive healthcare, says Rajesh Gokhale

New Delhi: India’s healthcare ecosystem is in transition as it has shifted from being a reactive care system to proactive with the help of vaccination, said Rajesh Gokhale, Secretary, Department of Biotechnology, Government of India. “Vaccination is an important component of proactive health where you actually take care of vaccinating…

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Bioinformatics Software QA Engineer (Remote Option) at Genentech

The Position Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world’s most complex health challenges, we ask bigger questions that challenge our industry and…

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Postdoctoral Research in Bioinformatics at Harvard University

We seek individuals with programming experience using Next Generation Sequencing data. A Bioinformatics/Genomics postdoctoral fellow position is available immediately in the Department of Pathology at Harvard Medical School/Beth Israel Deaconess Medical Center to study microRNAs in diagnostic and therapeutic applications for Alzheimer’s Disease. The position is under the direction of…

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Unexpected finding in mucus clearance system may inform future pulmonary disease treatment

Generation and validation of MUC5B/AC-KO cultures. (A) Overview of the MUC5B/MUC5AC gene-targeting approach via lentivirus-mediated delivery of sgRNA and CRISPR-Cas9. Transduced and sorted cells were differentiated at air-liquid interface (ALI). Once fully differentiated, the mucus gel was collected by apically washing cultures. HEK293T, human embryonic kidney–293T; FACS, fluorescence-activated cell sorting;…

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minimap2, before or after assembly?

minimap2, before or after assembly? 1 Dear all, I feel confused because I saw someone uses the minimap2 after demultiplexing, but before proceeding with the assembly (CANU) [case 1], and someone using the minimap2/samfile/BFCTools/medaka after assembly (always CANU) [case 2]. In case 1, the reference file used to align against…

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Electroporation Instruments Market 2022 Comprehensive Research and Competitive Landscape by 2028

Global Electroporation Instruments Market is specialized statistical research conducted by MarketsandResearch.biz that focuses on prospects for development and market enhancement. The core section also addresses market evaluation and special inspection. The primary goal of the research report is to provide critical competition information, current market trends, market potential, rate of…

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Research Fellow, Bioinformatics job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description We are seeking for a full-time bioinformatician in the cancer biology laboratory of Dr. Shruti Bhatt in the Department of Pharmacy at the National University of Singapore.  Check out Bhatt lab research focus, via this link:   pharmacy.nus.edu.sg/team/asst-prof-shruti-bhatt/ We are looking for candidates who share our excitement to…

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Bioinformatics Programmer II job with Baylor College of Medicine

Summary We are seeking a self-motivated, diligent, and result-oriented individual to join Dr. Bing Zhang’s Integrative Bioinformatics Laboratory (www.zhang-lab.org) as a Bioinformatics Programmer. The position rank is open (Bioinformatics Programmer I, II, or Senior Bioinformatics Programmer), depending on experience. Our research is funded by the National Cancer Institute (NCI), the…

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How to modify the genes of nature’s master manipulators

CRISPR, the Nobel Prize-winning gene-editing technology, is poised to once again have a profound impact on the fields of microbiology and medicine. A team led by CRISPR pioneer Jennifer Doudna and her longtime collaborator Jill Banfield has developed a clever tool to edit the genomes of bacteria-infecting viruses called bacteriophages…

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Thermo Fisher Platform for Science, Labbit & L7 ESP

Seeking feedback on three LIMS systems: Thermo Fisher Platform for Science, Labbit & L7 ESP 0 My team is planning to invest in a LIMS (laboratory information management system), and we have narrowed our best options to three platforms: Thermo Fisher Platform for Science Labbit L7 ESP We’re eager to…

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Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

In a recent study posted to the bioRxiv* server, researchers developed a messenger ribonucleic acid (mRNA) technology-based vaccine candidate against the monkeypox virus (MPXV) and evaluated its immunogenicity in animal models. Study: Polyvalent mRNA vaccination elicited potent immune response to monkeypox surface antigens. Image Credit: Wachiwit/Shuterstock Background The mRNA vaccines,…

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Downloading genes from NCBI in fasta format

I’m pretty new in bioinformatics. I need to download FASTA sequences of several genes. The list of genes I have assembled consists of 140 genes, so I’d rather do this through via code than download each gene manually from the NCBI database. The genes belong to 2 different organisms (bacteria)…

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r – Writing a fuction to Automate Repetitive Plotting in ggplot2

A great way to iterate over a list with a particular function would be to use lapply(). Here is an example that should demonstrate the concept. library(ggplot2) # data frames put into a list d1 <- data.frame(x=1:10, y=1:10) d2 <- data.frame(x=1:100, y=(1:100)^2) d3 <- data.frame(x=1:200, y=log(1:200)) mylist <- list(d1, d2,…

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JUPYTERLAB_SETTINGS_DIR defaults to JupyterHub root directory – JupyterHub

tisbam December 5, 2022, 2:34pm #1 Hi, I have setup Jupyterhub on a dedicated server : venv in /opt/jupyterhub Gitlab / Local authenticator with home directories automatically created Traefik proxy Default to /lab Is it the standard that the started jupyter server for each user looks for the config in…

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Researchers use loop-seq technology to decipher the mechanical code of DNA

A new study has deciphered the mechanical code of DNA to reveal previously unknown ways in which nature encodes biological information in DNA sequence. Led by Durham University, UK, an international team of researchers used a next-generation DNA-sequencing based technology called loop-seq, which they had developed, to show that the…

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go – OpenApi Generator Golang – Adding headers to request ending up in query params how to fix?

I’m trying to generate a go client but the generator won’t recognise a header and won’t let me pass it to the server as a header – instead it’s sent as a query param. info: title: API version: “1.2” servers: – url: example.com paths: /ping: get: summary: Checks if the…

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RStudio Launcher Plugin SDK: rstudio::launcher_plugins::local::LocalPluginApi Class Reference

Launcher Plugin API for the Local Plugin. More… #include <LocalPluginApi.hpp> Inheritance diagram for rstudio::launcher_plugins::local::LocalPluginApi: Detailed Description Launcher Plugin API for the Local Plugin. Constructor & Destructor Documentation ◆ LocalPluginApi() rstudio::launcher_plugins::local::LocalPluginApi::LocalPluginApi ( std::string  in_hostname, std::shared_ptr< comms::AbstractLauncherCommunicator >  in_launcherCommunicator  ) Constructor. Parameters in_hostname The name of the host running this instance of the…

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Nab-Paclitaxel Safety and Efficacy in Patients with Renal Impairment

The capacity to tolerate and respond to cancer treatment can be impacted by renal impairment. In this phase 3 trial, researchers compared nab-paclitaxel to docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC) and renal impairment. Before treatment, non-small cell lung cancer patients were divided into 2…

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Peroxisomes attenuate cytotoxicity of very long-chain fatty acids

Biochim Biophys Acta Mol Cell Biol Lipids . 2022 Nov 29;159259. doi: 10.1016/j.bbalip.2022.159259. Online ahead of print. Affiliations Expand Affiliations 1 Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima 770-8502, Japan; Graduate School of Biomedical Sciences, Tokushima University, Tokushima 770-8505, Japan. 2 Graduate School of Technology, Industrial…

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If a long linear dsDNA having blunt ends with 5’GAATTC3′ 3’CTTAGG5′ sequences at four places is cleaved by using EcoR1, how many DNA fragments are formed with cohesive ends on both sides? 1)5 2)4 3)3 4)2?

Question Description If a long linear dsDNA having blunt ends with 5’GAATTC3′ 3’CTTAGG5′ sequences at four places is cleaved by using EcoR1, how many DNA fragments are formed with cohesive ends on both sides? 1)5 2)4 3)3 4)2? for NEET 2022 is part of NEET preparation. The Question and…

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404 Not Found – ROMA BOOTS

IN 12 YEARS ROMA HAS DONATED 10 MILLION DOLLARS WORTH OF BOOTS IN 30+ COUNTRIES AROUND THE WORLD. We’re sorry, but the page you requested could not be found. Subscribe Sign up to get the latest on sales, new releases and more … /* =============================================== // Reveal module // ===============================================…

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Link between breast implants after mastectomy, risk of lymphoma: Research | Health

Anaplastic large-cell lymphoma (ALCL) is a rare disease whose incidence has increased recently; this increase may be related to the expanding popularity of textured breast implants. Some breast cancer patients who have mastectomy may question whether the advantages of receiving reconstructive implants outweigh the possibility of having a second cancer…

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We conclude that the 18S stem-loop structure is recognized at least twice during pre-rRNA processing.

Abstract ABSTRACT The loop of a stem structure close to the 5′ end of the 18S rRNA is complementary to the box A region of the U3 small nucleolar RNA (snoRNA). Substitution of the 18S loop nucleotides inhibited pre-rRNA cleavage at site A1, the 5′ end of the 18S rRNA,…

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CD44 promotes angiogenesis in myocardial infarction through regulating plasma exosome uptake and further enhancing FGFR2 signaling transduction

Background: Since angiogenesis occurs as the pathological process following myocardial infarction to alleviate ischemia, therapeutic angiogenesis has been proposed to be a cardioprotective strategy. CD44 has been implicated in endothelial cell functions and its role has been well established in angiogenesis for years. Although recent studies indicate the close correlation…

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Compressing BAM, SAM, CRAM | Genozip

How good is Genozip at compressing BAM files? ​ See Benchmarks. ​ Compressing a BAM, SAM or CRAM file  ​ In the rest of this page we will give examples of BAM files. Genozip is also capable of compressing SAM files, and with some limitations, CRAM files as well. ​…

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Role of STING protein in breast cancer: mechanisms and therapeutic implications

Review doi: 10.1007/s12032-022-01908-4. Affiliations Expand Affiliations 1 Department of Vascular and Endocrine Surgery, Xijing Hospital, The Air Force Medical University, Xi’an, 710000, China. 2 Department of Vascular and Endocrine Surgery, Xijing Hospital, The Air Force Medical University, Xi’an, 710000, China. vascularzhang@outlook.com. Item in Clipboard Review Yue Jiang et al. Med Oncol….

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genbank sequence format

HHS Vulnerability Disclosure, Help This document is an overview of the Entrez databases, with general information on If you are not sure that the “Save” option in your program will do this for you, use “Save As”, In Excel, select “Save As” from the File menu. optimizations to reduce memory…

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Genetic genealogy ‘game changer’ offers hope for near-unsolvable Ontario cold cases

“Now that we have the killer’s DNA, we just need a name to go with it.” “Forensic testing was done and DNA was identified, but it does not link to any known offenders in the national DNA data bank.” “While the offender is not on the national DNA data bank,…

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LJ Potential Parameters – LAMMPS General Discussion

Hello!Can anyone help me with how to find LJ potential parameters for Lammps? Suppose I want to know LJ parameters for h-BN structure simulation in lammps! I seriously doubt that a set of Lennard-Jones parameters will create a good representation of your system. You will either need a more complex…

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Error when Installing BioConductor Package (‘affy’)

Hi, when I try to install Bioconductor package ‘affy’ Experience below error\ May I know how do I fix this? I’m currently using R4.2.2 on MacBook Air, M1\ R version 4.2.2 (2022-10-31) — “Innocent and Trusting”\ Copyright (C) 2022 The R Foundation for Statistical Computing\ Platform: aarch64-apple-darwin20 (64-bit) BiocManager::install(“affy”) ‘getOption(“repos”)’…

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Espressif’s Ali Hassan Shah Walks Through Putting a TinyML Gesture Recognition Model on an ESP32-S3

Espressif’s Ali Hassan Shah has penned a guide to getting started with the company’s ESP-DL TinyML edge AI framework, using it to deploy a gesture recognition model on to an ESP32-S3 microcontroller. “Artificial intelligence transforms the way computers interact with the real world. Decisions are carried by getting data from…

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EMDB < EMD-20433

Field: Choose…EMDB IDTitleAuthorORCIDEM methodCurrent statusDeposition dateRelease dateDeposition siteLast processing siteFitted modelsRaw dataResolutionResolution methodSoftwareLigand nameComplex nameDomain nameDrug nameGO term nameInterPro term nameChEBI term nameExternal reference Publication titlePublication yearJournalPublication author Sample typeSample nameOrganismOrganism (NCBI code)StrainOrganTissueCellOrganelleCellular LocationE.C. numberMolecular Weight methodMolecular Weight (Da)Recombinant ExpressionRecombinant organismRecombinant organism (NCBI code)Recombinant strainRecombinant expression cellRecombinant expression plasmidDNA/RNA classificationDNA/RNA…

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Differentially expression analysis of orthologous genes between two species

Differentially expression analysis of orthologous genes between two species 1 @4dbfec5b Last seen 10 hours ago Netherlands Hi people, I want to use DESeq2 for differentially expression analysis of orthologous genes between two different species. I am not experienced at all using R and DESeq2, but I think at the…

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TDF to bed graph — IGV on command line

TDF to bed graph — IGV on command line 0 Hi all, I’m trying to convert some TDF files to bedgraph files so that I can do a genomic leftover on them (as far as I can tell, I can’t lift over TDF files). This google group answer here (groups.google.com/g/igv-help/c/RcZw5YB5SOQ)…

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“Our generation will see an artificial intelligence that equals or exceeds that of the human being”

since he saw as a child 2001: A Space Odyssey, Oriol Vinyals knew that he wanted to dedicate himself to artificial intelligence. “I was very interested in how naturally Hal 9000, the computer, spoke. Could we achieve something like this?”, this teenager from Sabadell was already wondering. Today, at 39,…

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Financial Contrast: MaxCyte (NASDAQ:MXCT) vs. Protalex (OTCMKTS:PRTX)

MaxCyte (NASDAQ:MXCT – Get Rating) and Protalex (OTCMKTS:PRTX – Get Rating) are both medical companies, but which is the better stock? We will compare the two businesses based on the strength of their analyst recommendations, valuation, earnings, dividends, institutional ownership, risk and profitability. Analyst Recommendations This is a breakdown of…

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Genome Bioinformatics Analyst at UPMC

Description The Genome Bioinformatics Analyst works independently to curate disease, gene and variant knowledge including variant interpretation, reporting and consultation with laboratory staff, physicians and genetic counselors. The analyst participates in clinical test development, validation and maintenance of data analysis pipelines, monitoring of quality metrics and the analysis of large…

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Post-doc in Computer Science / Bioinformatics – University of Bern – job portal

Post-doc in Computer Science / Bioinformatics We are seeking to hire a person with a PhD in bioinformatics, computational biology, data science, computer science, statistics or applied mathematics. Preferably the candidate should have experience of using large data sets to undertake projects with a particular focus on the integration of…

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19 Vacancies, Check Posts, Eligibility and Other Details

DRDO-DFRL Recruitment 2022: 19 Vacancies, Check Posts, Eligibility and Other Details DRDO-DFRL Recruitment 2022: The Defence Food Research Laboratory (DFRL) is an Indian defence laboratory of the Defence Research and Development Organisation (DRDO), located in Mysore, Karnataka. It conducts research and development of technologies and products in the area of…

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Biochemical characterization of the two novel mgCas12a proteins from the human gut metagenome

Discovery of 11 new Cas12a candidates from a human gut microbiome database To discover new members of the Cas12a protein family, we built a pipeline that searches and sorts out new candidates from the National Center for Biotechnological Information (NCBI) human metagenome database. Using this search pipeline (Fig. 1a), we initially…

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recommend tools for scRNAseq cell type annotation

recommend tools for scRNAseq cell type annotation 1 Dear all, May I know if there are recommended tools/webs for the cell type annotation? Say, I have the cell expression matrix, and want to generate a cell type/labels file based on the expression matrix and the prior knowledge of the cell…

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A strategy to thermally stabilize microneedle vaccine technology

Credit: Thanh Nguyen/University of Connecticut Researchers in the Department of Biomedical Engineering—a shared department between the UConn Schools of Dental Medicine, Medicine, and Engineering—unlocked a new strategy using sugar molecules to thermally stabilize their existing microneedle vaccine technology, eliminating the need for cold-chain storage. Associate Professor Thanh Duc Nguyen from…

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Bioinformatics Services Market Size, Growth, Share-Global Trends, Market Demand, Development Status, Growth Opportunities and Forecast 2028

A quantitative analysis of regional markets is combined with a fresh perspective on the target industry in the Bioinformatics Services Market study. The research covers market size, drivers and weaknesses, key players, a sector overview, and a geographic forecast, among other topics. It also contains information on the business climate,…

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Bar chart not coming in the desirable way – tidyverse

Hi,I have a data for tracking attendance of teachers. In the sample data I have given the variable attendance. 1 means attended and 2 means absent. Now I need to get a bar chart where I get the Instructors name on the X-axis and the average attendance % on the…

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ggplot2 – remove NA’s from only one Variable in scatter plot with 2 variables over time in R / ggplot

I want to plot 2 variables over a time period with ggplot. One of the variables contains NAs. I want to drop the NAs from the plot without losing the value for the other variable. Right now, ggplot plots all NAs in a line at the top of the y-axis….

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Page Not Found – Jupyter Community Forum

Sign Up Log In Log In Popular Official Mastodon account(s)?Meta 403 Forbidden Error when using Azure AD for authenticationZero to JupyterHub on Kubernetes Install pip package such as backtrader in the jupyter/datascience-notebook imagediscuss error to download file in jupyterhub – failed – network errorJupyterHub [ANN] Jupyter Core 5.0Meta [ANN] New…

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Solved 2. Nucleic acids ( 5 points) a. In the Sanger

Transcribed image text: 2. Nucleic acids ( 5 points) a. In the Sanger (dideoxy) method for DNA sequencing, a small amount of dideoxynucleotides triphophosphate-say, ddCTP – is added to the sequencing reaction along with a larger amount of corresponding JCTP. i. What is the function of the ddCTP (i.e., why…

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RStudio fails to start up after update to latest version and update of R to 4.2.2 – RStudio IDE

Error Information: Nothing visibleDescription of issue –Updated R and Rstudio after not using it since 2017 (although that version worked)R Works OKRStudio fires up icon then immediately fails with a segmentation fault Attempted steps taken to fix –Deleted all RStudio files and then re-downloaded RStudio . System Information: RStudio Edition:…

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KSUM to organise bootcamp for SaaS startups

The Kerala Startup Mission (KSUM) will be conducting a two-day free bootcamp for start-ups on December 10. The camp is being organised in association with CareStack at its office in Technopark Phase-3 here. Founders and leaders of CareStack, a startup which develops SaaS (Software as a Service) products, will lead the bootcamp….

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Guided exercises to practice ATAC-seq/ChIP-seq analysis?

Guided exercises to practice ATAC-seq/ChIP-seq analysis? 1 Hello everyone! I was wondering if there is any way to practice ATAC-seq/ChIP-seq analysis with guided exercises. Do you know of any resource? RNA-seq would be great too, although I have seen many of them online, if there is any particularly good resource,…

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Metagenomics Maps How the Gut Microbiome Is Altered in Parkinson’s Disease

New research from the University of Alabama at Birmingham says the gut microbiome is involved in multiple pathways in the pathogenesis of Parkinson’s disease. The findings, published in Nature Communications, show a wide imbalance in microbiome composition in persons with Parkinson’s disease. The study is the largest microbiome study conducted at the highest…

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Acquisition of antibodies to Plasmodium falciparum and Plasmodium vivax antigens in pregnant women living in a low malaria transmission area of Brazil | Malaria Journal

WHO. World Malaria Report. Geneva: World Health Organization; 2019. Google Scholar  Rogerson SJ, Hviid L, Duffy PE, Leke RF, Taylor DW. Malaria in pregnancy: pathogenesis and immunity. Lancet Infect Dis. 2007;7:105–17. Article  CAS  PubMed  Google Scholar  Salanti A, Dahlback M, Turner L, Nielsen MA, Barfod L, Magistrado P, et al….

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PRC2 direct transfer from G-quadruplex RNA to dsDNA: Implications for RNA-binding chromatin modifiers

Abstract The chromatin-modifying enzyme, Polycomb Repressive Complex 2 (PRC2), deposits the H3K27me3 epigenetic mark to negatively regulate expression at numerous target genes, and this activity has been implicated in embryonic development, cell differentiation, and various cancers. A biological role for RNA binding in regulating PRC2 histone methyltransferase activity is generally…

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With CRISPR gene scissors in opposition to HIV: First try is underway within the USA

With CRISPR gene scissors in opposition to HIV: First try is underway within the USA On December 1st, World AIDS Day, information from the USA presents hope for these affected. In July 2022, the Californian biotech firm Excision BioTherapeutics dared to make use of a brand new remedy idea with…

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About: Mir-194 microRNA precursor family

In molecular biology, miR-194 microRNA precursor is a small non-coding RNA gene that regulated gene expression. Its expression has been verified in mouse (MI0000236, MI0000733) and in human (MI0000488, MI0000732). mir-194 appears to be a vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate…

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Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis

Wang, J., Garancher, A., Ramaswamy, V. & Wechsler-Reya, R. J. Medulloblastoma: from molecular subgroups to molecular targeted therapies. Annu. Rev. Neurosci. 41, 207–232 (2018). Article  CAS  PubMed  Google Scholar  Cavalli, F. M. G. et al. Intertumoral heterogeneity within medulloblastoma subgroups. Cancer Cell 31, 737–754.e736 (2017). Article  CAS  PubMed  PubMed Central …

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A high-throughput multispectral imaging system for museum specimens

The two-dimensional nature of many pinned Lepidoptera specimens allows us to omit some technical considerations, such as the variable incident angles that need to be carefully considered when imaging 3D objects, and our multi-spectral imaging rig with its custom designed platform can image both the dorsal and ventral sides of…

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RNAi for Therapeutic Market May See a Big Move | Moderna, BOC Sciences, Abogen Biosciences

Latest Study on Industrial Growth of RNAi for Therapeutic Market 2022-2027. A detailed study accumulated to offer Latest insights about acute features of the RNAi for Therapeutic market. The report contains different market predictions related to revenue size, production, CAGR, Consumption, gross margin, price, and other substantial factors. While emphasizing…

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Possible bugs in Rsubread/stad-alone featureCounts options fracOverlap and largestOverlap with fractional counts

Hi, running Rsubread 2.8.2/2.12.0 or featureCounts 2.0.3/2.0.1, I stumbled over two issues when allowing ambiguous read assignment (-O/allowMultiOverlap) 1) regarding assignment via minimum fractional overlap (–fracOverlap) using featureCounts stand-alone binary. 2) when combined with –/largestOverlap and –/fraction using Rsubread featureCounts function or the stand-alone binary. to 1) Assume a read…

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Copy number variations in patients with idiopathic recurrent pregnancy loss: an array-CGH approach

Copy number variations in patients with idiopathic recurrent pregnancy loss: an array-CGH approach Atıf İçin Kopyala Yildiz O., SILAN F., Karakaya T., Özdemir Ö. Turkish Journal of Medical Sciences, cilt.52, sa.5, ss.1689-1696, 2022 (SCI-Expanded) …

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The Promise of RNA-Based Therapies

Published a day ago Submitted by CRB Decades of scientific progress in understanding the root cause of many formerly intractable diseases has opened up new treatment options, namely through RNA-based therapies. This second wave of biopharma, in which our understanding of the ways coding portions of our genome relate to…

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AWS launches Amazon Omics for precision medicine

To enhance clinical insights at the point of care and help identify the best treatment or prevention options for patients, Amazon Web Services has launched a service that utilizes artificial intelligence (AI), machine learning, and other AWS and partner products and services to run IT-heavy bioinformatics workflows.  WHY IT MATTERS…

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How can I calculate PRS for all samples by using PRSice-2.

How can I calculate PRS for all samples by using PRSice-2. 0 Hi. I am trying to calculate PRS by using PRSice-2. I’d like to know how to handle the model. When I provide same gwas results to PRSice-2’s –base option, is the model always same? I have several thousands…

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Some People More Prone to COVID-19 Vaccine Side Effects

Among individuals who have received COVID-19 vaccines, younger people, females, and those who got the second dose of the Moderna COVID-19 vaccine report more side effects from COVID-19 vaccines that may have led to moderate and severe limitations, according to a recent paper (Front Public Health 2022; doi: 10.3389/fpubh.2022.975781). These…

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Changes in Protein Structure May Act as Parkinson’s Biomarkers | Potential for Easier Diagnosis in Analysis of Protein Shape

Changes in the structure of 76 proteins in the cerebrospinal fluid (CSF) of people with Parkinson’s disease were seen when compared with those of healthy individuals, a study reported. Its researchers believe their work is the first to look at protein structure — rather than abundance — to identify potential new…

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Where to find vcf of dbsnp build 144 ?

Where to find vcf of dbsnp build 144 ? 0 Hi everyone, I have zipped vcf files that I would like to annotate using hg19 bsnp144. I have bed files for each chromosome but, based on other biostar answers (How to add rsIDs to VCF?), it seems it is easier…

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Makeblastdb – ECHEMI

0  Upvotes · 5 Comments 0  Upvotes · 1 Comments 0  Upvotes · 1 Comments 0  Upvotes · 2 Comments 0  Upvotes · 2 Comments 0  Upvotes · 6 Comments 0  Upvotes · 12 Comments Read more here: Source link

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dharmacon sirna design

Please feel free to visit our Privacy Policy and Cookie Policy with regards to processing your data. Article Customer Support Sequence characteristics of functional siRNAs. Human and mouse genes are each targeted with multiple shRNA constructs that have been cloned into the pGIPZ lentiviral vector. GRCF Management Team. In the…

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biology questions – hw 2.docx – 1) The red blood cells in your body are going through the process of transcription. What are the enzymes needed to make

1)The red blood cells in your body are going through the process of transcription. What arethe enzymes needed to make rRNA and the basic steps in which this process occurs?A)A ‘specific’ transcription factor binds to the promoter region and allows RNA PolymeraseI to read the DNA and create rRNA.B)A ‘specific’…

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The circRNA expression profile of colorectal inflammatory cancer transformation revealed potential predictive biomarkers

Cite this Article How to cite Lu L, Liu Y, Zhang G, Xu Y, Hu D, Ji G, Xu H, . The circRNA expression profile of colorectal inflammatory cancer transformation revealed potential predictive biomarkers. Aging (Albany NY). 2022 Nov 29; . doi.org/10.18632/aging.204406 [Epub ahead of print] Copy or Download citation:…

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scikit learn – Importing sklearn in Databricks downgrades the Python root logger?

Using Python 3.8.10 in an Azure Databricks notebook, runtime 10.4: >>> import logging >>> type(logging.root) logging.RootLogger Ok, that was expected. What’s surprising is this: >>> import sklearn # version is 1.1.3 >>> import logging >>> type(logging.root) numpy.distutils.log.Log This is problematic because numpy’s Log is not as powerful as Python’s; in…

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Datasets | TogoVar

Variant frequencies for which you can apply for use of individual-level data∗1 to the NBDC human databases∗2 Click the links at the Included controlled-access datasets to apply for use of individual-level data ∗1:fastq/bam/cel files and/or lists of genotype data etc.∗2:Japanese Genotype-phenotype Archive (JGA) / AMED Genome group sharing Database (AGD)…

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