Category: Research

ITWeb TV: Open-source AI: Unlocking potential for South Africa’s SMEs

ITWeb’s Lungile Msomi talks to African Academy of Artificial Intelligence co-founders, Greg Serandos and Quinton Jacobs, about business adoption of AI, the drive for relevant skills and how South Africa can leverage the technology for competitive advantage on the continent. #itwebtv #ai #opensource While artificial intelligence (AI) holds the potential…

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TdIF2 is a nucleolar protein that promotes rRNA gene promoter activity

@article{Koiwai2011TdIF2IA, title={TdIF2 is a nucleolar protein that promotes rRNA gene promoter activity}, author={Kotaro Koiwai and Satoshi Noma and Yasuhiro Takahashi and Takahide Hayano and So Maezawa and Kousuke Kouda and Takuro Matsumoto and Masahiro Suzuki and Masaki Furuichi and Osamu Koiwai}, journal={Genes to Cells}, year={2011}, volume={16}, url={https://api.semanticscholar.org/CorpusID:205293848} } TdIF2 might…

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Translational Regenerative Medicine market is estimated to grow at a CAGR of 24.3% by 2034: Visiongain

Visiongain Reports Ltd Visiongain has published a new report entitled: Translational Regenerative Medicine Market Report 2024-2034: Forecasts by Product (Stem Cell Therapy (Autologous, Allogenic), Tissue Engineering (Scaffold, Hydrogels), Gene Therapy, Others)), by Application (Oncology, Dermatology, Musculoskeletal, Neurology, Cardiovascular, Wound Healing, Ophthalmology, Others) AND Regional and Leading National Market Analysis PLUS…

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See #BuildWithAI: Introduction to Python & Cloud Computing with Google Gemini

Introduction to Python & Cloud Computing with Google Gemini is an innovative workshop designed for beginners who are eager to delve into the world of cloud computing and AI. This workshop focuses on harnessing the power of Python, a leading programming language, in combination with Google Cloud’s cutting-edge products: Gemini…

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Upload DNA Data For Free From Any Genetic Test

Upload your DNA data from almost any genetic test. Easily upload DNA data from a broad spectrum of genetic tests to Sequencing.com, your central hub for genetic insights. From the moment your data is uploaded, you unlock access to an extensive selection of DNA analysis apps and reports, designed to transmute…

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Scaling of MD with domain decomposition on JUWELS Cluster – Developers discussions

GROMACS version: 2024-dev-20240201-787d96c7a9-unknownGROMACS modification: YesI’m conducting some performance tests on the JUWELS Cluster, trying to see the improvement in performance that DD can bring within a single node. GROMACS build infoHere, GROMACS was built using GCC v11.4.0, uses OpenMP and OpenMPI v4.1.5, and builds its own FFTW v3.3.8. JUWELS Cluster…

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Bioinformatics Developer (Intermediate To Senior) in New Zealand

Job Details Auckland, Auckland, New Zealand Netvalue Ltd Posted 1 day ago Want updates for this and similar Jobs? This advertiser has chosen not to accept applicants from your region. Full Job Description Bioinformatics Developer (Intermediate to Senior) Bioinformatics Developer (Intermediate to Senior) 15 openings But enough about us, what…

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Senior Bioinformatics Analyst in New York, NY for Weill Cornell Medicine

Details Posted: 09-Feb-24 Location: New York, New York Salary: Open Categories: Academic/Faculty Medical – Clinical Senior Bioinformatics Analyst Title: Senior Bioinformatics Analyst Location: Upper East Side Org Unit: Steven Josefowicz Lab Work Days: Monday-Friday Exemption Status: Exempt Salary Range: $108,600.00 – $126,600.00 *As required under NYC Human Rights Law Int…

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Translational Regenerative Medicine market is estimated to

Visiongain has published a new report entitled: Translational Regenerative Medicine Market Report 2024-2034: Forecasts by Product (Stem Cell Therapy (Autologous, Allogenic), Tissue Engineering (Scaffold, Hydrogels), Gene Therapy, Others)), by Application (Oncology, Dermatology, Musculoskeletal, Neurology, Cardiovascular, Wound Healing, Ophthalmology, Others) AND Regional and Leading National Market Analysis PLUS Analysis of Leading…

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Get mRNA sequence from amino acid sequence using BioPython

Get mRNA sequence from amino acid sequence using BioPython 1 I have a sequence of amino acids like “MVLLV” and I want to know what mRNA corresponds to that, I’m using biopython for this, but I just know the back_transcribe(), to revert the RNA to DNA, how can I do…

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Using OIDC and Oauth2 in openapi 3

I hope someone can help me. I have been looking at lots of forums and have not been able to find any answers. I am hoping to use OpenAPI 3 and OIDC to get access token. I am generating a Java client using codegen cli – java -jar swagger-codegen-cli-3.0.8.jar generate…

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Supercharge Your RStudio Workflow with ChatGPT and gptstudio

Supercharge Your RStudio Workflow with ChatGPT and gptstudio Table of Contents: Introduction Benefits of Using Large Language Models in Rstudio 2.1 Increased Efficiency 2.2 Enhanced Capabilities Available Models for Rstudio 3.1 OpenAI’s GPT-4 3.2 Hugging Face Models 3.3 Anthropics’ Claude 3.4 Google’s PaLM Models Setting up Rstudio and Packages Installation…

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Belantamab Mafodotin Tops Daratumumab in Multiple Myeloma

TOPLINE: Belantamab mafodotin plus a combination of bortezomib and dexamethasone improved median progression-free survival (PFS) by 23 months in patients with relapsed or refractory multiple myeloma compared with daratumumab alongside the same combination. METHODOLOGY: Belantamab mafodotin, a first-in-class anti-BCMA monoclonal antibody conjugate, was approved in the US in 2020 for…

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Loss.backward() error when using custom autograd function – vision

Hi All! I am facing the error:AttributeError: ‘CheckpointFunctionBackward’ object has no attribute ‘input_tensors’ Please find the implementation of my custom backward function. Hi @torch2.0, When sharing code, please copy and paste the code and wrap it within 3 backticks “`, rather than sharing a screenshot. Your issue is that you…

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Ants of French Guiana: 16S rRNA sequence dataset

doi: 10.3897/BDJ.11.e91577. eCollection 2023. Affiliations Expand Affiliations 1 UMR Écologie des Forêts de Guyane (AgroParisTech, CIRAD, CNRS, INRAE, Université de Guyane, Université des Antilles), Kourou, French Guiana UMR Écologie des Forêts de Guyane (AgroParisTech, CIRAD, CNRS, INRAE, Université de Guyane, Université des Antilles) Kourou French Guiana. 2 Laboratoire Evolution et…

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Preparation and recognition mechanism study of an scFv targeting chloramphenicol for a hybridization chain reaction-CRISPR/Cas12a amplified fluoroimmunoassay

. 2024 Mar 8:1293:342283. doi: 10.1016/j.aca.2024.342283. Epub 2024 Jan 22. Affiliations Expand Affiliations 1 College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China. 2 Medical College, Nankai University, Tianjin, 300500, China. Electronic address: wangshuo@nankai.edu.cn. 3 College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China….

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Assessing the Durability, Tolerability of Loncastuximab in R/R DLBCL

CASE A 73-year-old woman presented with fever, headaches, and 7-lb unintentional weight loss​. Medical history: no family history of cancer, and hyperlipidemia that was well controlled with simvastatin. Physical exam: palpable bilateral cervical lymphadenopathy​ Laboratory results: lactate dehydrogenase, 265 U/L (280 U/L upper limit); Hemoglobulin, 10.8 g/dL; bilirubin, 1.3 mg/dL…

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Singapore ups its AI strategy with Google Cloud collaboration

Though a small Southeast Asian nation with a population of 5.45 million, Singapore has long voiced its big ambitions to stand at the forefront of global technological innovation, including AI. Supported by its partners Google Cloud, The Ministry of Communications and Information (MCI), Digital Industry Singapore (DISG), Smart Nation Group…

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Exploring the Viral Reservoir of HIV-1: Implications for Treatment

Exploring the Viral Reservoir of HIV-1 The fight against HIV-1, the virus responsible for the global AIDS pandemic, hinges on understanding the virus’s reservoirs within the human body. A recent study delves into the longitudinal evolution of these viral reservoir cell pools, shedding light on their characteristics, behavior, and potential…

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A Simple Overview for Proteins Molecular Dynamics Simulations Using GROMACS

About Gromacs – Gromacs. s.d. Consulté le 5 mai 2023. www.gromacs.org/About_Gromacs Baker, D., Sali, A.: Protein structure prediction and structural genomics. Science 294(5540), 93–96 (2001). doi.org/10.1126/science.1065659 Beckstein, O., et al.: Ion channel gating: insights via molecular simulations. FEBS Lett. 555(1), 85–90 (2003). doi.org/10.1016/s0014-5793(03)01151-7 CrossRef  Google Scholar  Bowman, A.L., Ridder, L.,…

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Bristol Myers Squibb hiring Machine Learning/AI Scientist Computational Tissue Imaging Research, Translational Bioinformatics in Cambridge, MA

Working with UsChallenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work…

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The woman behind the genomic scissors CRISPR-Cas9 :: Understanding Animal Research

For this year’s women and girls in science day, UAR chose to highlight the career of a world-renowned scientist and how animal research shaped her path to becoming one of the most respected and revered researchers. Working in fundamental science and microbiology, Emmanuelle Charpentier gradually obtained prizes, eventually receiving one…

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Moderate Mapping percentage

Moderate Mapping percentage 1 Hi all, I received my sequenced transcriptome and genomic data from my service provider and started working with it. Both the DNA and RNA data passed quality metrics post trimming. But the mapping percentage comes out to be 90% using bowtie-DNA and 85% using Hisat2-RNA. I…

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What’s New in IntelliJ IDEA Ultimate 2023.3

Releases The Ultimate edition of IntelliJ IDEA goes beyond the basics, offering a comprehensive suite of features, including in-depth profiling capabilities, database tools, built-in support for many web and enterprise frameworks, and more. In this latest v2023.3 release, we’ve rolled out a suite of new features to enhance your coding…

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Moderna’s mRNA-1647 Vaccine Shows Promise in Phase 3 Clinical Trials for CMV

Exciting progress is being made in the world of vaccine development as Moderna, Inc., the renowned American pharmaceutical and biotechnology company, has reported highly promising results for their experimental mRNA vaccine against cytomegalovirus (CMV). The vaccine, known as mRNA-1647, is the first of its kind to enter phase 3 clinical…

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What Metagenomics is and Its Applications in Healthcare and Biotechnology – Magazines Weekly

Metagenomics is simply the study of microbes in the natural living environment that involves complex microbial communities where they exist. The study helps examine an organism’s genomic composition, including all its microbes. Rather than considering the concept of an organism and microbes as separate entities, regard them as a community…

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Understanding the Role of Rare Genetic Variants and Their Impact on Health

Understanding the Role of Rare Genetic Variants Recent research on the UK Biobank cohort, a large-scale genetic data set, has shed light on the significant role of rare genetic variants (RVs) in complex trait heritability. The study confirms that these RVs account for a substantial portion of the complex trait…

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Diversity of Unusual Ribosomal Genes and Ecological Origin of Rice ( Oryza spp.)

Author Listed: Xiyu Tan (College of Life Science, South China Agricultural University, Guangzhou 510642, China) Guixiang Peng (College of Natural Resources and Environment, South China Agricultural University, Guangzhou 510642, China) Sajid Muhammad (College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310023, China) Sidra Kaleem (Riphah Institute of Pharmaceutical Sciences, Islamabad…

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The Evolution from HG19 to HG38

Welcome to another blog post! ‍ Reference genomes are essential benchmarks of a species’ genome that facilitate the accurate comparison of individual genomes and are crucial tools for identifying genetic variants and diagnosing rare diseases. Here, we will explore the evolution of the human reference genome, focusing on the transition…

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CorGTA Inc. hiring Machine Learning Engineer (Vertex AI) in Canada

*****This company is a Data Consultancy & Solution Provider with high-profile clients that works with Data Scientists, Data Engineers, and Software Engineers to solve any & all business problems. (Data & Analytics Strategy, Data Governance, Data Warehousing, Predictive Analytics, & Cloud BI Services) Machine Learning Engineer (Vertex AI) Job Title:…

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Novel Mechanism Implicates Faulty Mitochondrial DNA in Chronic Inflammation

In a groundbreaking study, researchers at the Salk Institute and the University of California, San Diego have unveiled a novel mechanism that implicates improperly functioning mitochondrial DNA (mtDNA) in the activation of an inflammatory pathway. Chronic inflammation is a key contributor to various human diseases and aging, and understanding its…

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Gromacs: gmx::BerendsenTemperatureCoupling Class Reference

Public Member Functions real  apply (Step step, int temperatureGroup, real currentKineticEnergy, real currentTemperature, const TemperatureCouplingData &temperatureCouplingData) override   Apply the v-rescale temperature control.   void  connectWithPropagator (const PropagatorThermostatConnection &connectionData, int numTemperatureGroups) override   Connect with propagator – Berendsen only scales start step velocities.   void  writeCheckpoint (std::optional< WriteCheckpointData > checkpointData,…

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The Henry M. Jackson Foundation for the Advancement of Military Medicine hiring Senior Bioinformatics Scientist in Bethesda, MD

Join the HJF Team!The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a nonprofit organization dedicated to advancing military medicine. We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians alike….

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Contigs number vs NNN gap % in WGS

Contigs number vs NNN gap % in WGS 0 Hi all, I have two fasta files of bacterial whole genome sequence assembly (same genome) generated by spades generated by spades > extra scaffolding step using multi-csar, by comparing it to 5 close genomes. quast statistics as below : Genome 1…

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vacuum OpenAPI Linter: Bundle OpenAPI spec

Lots of OpenAPI specifications are exploded out across lots of different files. This is great for maintainability, but not so great for portability. Many OpenAPI tools do not support exploded / multi-file OpenAPI specifications. Loading and locating references can be tricky, particularly when they are spread across local or remote…

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Index of /ubuntu/ubuntu/pool/universe/f/fastp/

../ fastp_0.20.0+dfsg-1build1.debian.tar.xz 22-Mar-2020 16:49 3892 fastp_0.20.0+dfsg-1build1.dsc 22-Mar-2020 16:49 2004 fastp_0.20.0+dfsg-1build1_amd64.deb 22-Mar-2020 17:11 191764 fastp_0.20.0+dfsg.orig.tar.xz 22-Jul-2019 17:13 64664 fastp_0.20.1+dfsg-1.debian.tar.xz 27-Apr-2020 19:01 3940 fastp_0.20.1+dfsg-1.dsc 27-Apr-2020 19:01 1961 fastp_0.20.1+dfsg-1_amd64.deb 27-Apr-2020 20:21 192944 fastp_0.20.1+dfsg.orig.tar.xz 27-Apr-2020 19:01 64864 fastp_0.23.2+dfsg-2.debian.tar.xz 11-Dec-2021 23:24 8476 fastp_0.23.2+dfsg-2.dsc 11-Dec-2021 23:24 1993 fastp_0.23.2+dfsg-2_amd64.deb 11-Dec-2021 23:24 172754 fastp_0.23.2+dfsg.orig.tar.xz 08-Dec-2021 05:28 82224 …

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GenomeFace: a deep learning-based metagenome binner trained on 43,000 microbial genomes

Abstract Metagenomic binning, the process of grouping DNA sequences into taxonomic units, is critical for understanding the functions, interactions, and evolutionary dynamics of microbial communities. We propose a deep learning approach to binning using two neural networks, one based on composition and another on environmental abundance, dynamically weighting the contribution…

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Skingpt4 errors python – Models

warning libmamba Added empty dependency for problem type SOLVER_RULE_UPDATECould not solve for environment specsThe following packages are incompatible├─ libzlib is installable and it requires│ └─ zlib 1.2.13 _5, which can be installed;├─ mamba is installable and it requires│ └─ python_abi 3.11. _cp311, which requires│ └─ python 3.11. *_cpython, which can…

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EHA Library – The official digital education library of European Hematology Association (EHA)

Strictly Necessary Cookies (Always Active) MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies…

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The formation of inflammation in the inflammatory pathways is caused by the defective DNA dispensing system during mitochondrial stress

Scientists have discovered a new way in which misplaced mitochondrial DNA (mtDNA) can be a cause of inflammation, which may equip clinicians with the tools to use these diseases as therapeutic interventions against inflammation associated with aging and other diseases. Credit: SciTechDaily.com. Salk scientists show a pathway for mouse cell…

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RunComfy Reviews – 2024

RunComfy Description Our cloud-based platform automatically configures your ComfyUI work flow. Each workflow comes with all the necessary custom nodes and model, ensuring an easy start. ComfyUI Cloud GPUs are high-performance and will unlock the full potential of any creative project. Profit from faster processing rates at market-leading speeds, ensuring…

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Inferring divergence times within pikas (Ochotona spp.) using mtDNA and relaxed molecular dating techniques.

Inferring divergence times within pikas (Ochotona spp.) using mtDNA and relaxed molecular dating techniques. Inferring divergence times within pikas (Ochotona spp.) using mtDNA and relaxed molecular dating techniques. Mol Phylogenet Evol. 2009 Oct; 53(1):1-12. Animals Animals DNA, Mitochondrial …

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DNA Processor Microfluidic Chips: Revolutionary Development in Bio-Computing

In the realm of technology and computing, a groundbreaking development has been made. Researchers have successfully developed a processor using DNA, where a microfluidic chip can perform mathematical calculations and store data. This innovative approach to bio-computing demonstrates the immense potential that lies in DNA-based computing systems. The ability of…

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Victoria Maplot / vmaplot

This video is a private video uploaded by pomidorka. Only active members can watch private videos. Please log in or sign up for free. Duration: 2:22 Views: 9.5K Submitted: 8 months ago Submitted by: Read more here: Source link

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KBR, Inc. hiring Senior Bioinformatics/Data Scientist in Houston, TX

TitleSenior Bioinformatics/Data Scientist BELONG. CONNECT. GROW. with KBR. At KBR, we define the future. We are a company of innovators, thinkers, creators, explorers, volunteers, and dreamers. But we all share one goal: to improve the world responsibly and safely. KBR is seeking a Senior Data Scientist with Bioinformatics experience. The…

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jobs – QIIME 2 Forum

About the q2-jobs category 0 664 July 5, 2018 MS/PhD/Postdoc position in the Department of Biomedical Informatics at the University of Arkansas for Medical Sciences 0 166 June 7, 2023 Research Software Engineer for microbiome bioinformatics at ETH Zurich 0 406 June 7, 2023 Microbial Ecology Postdoctoral Researcher at Smithsonian,…

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Bioinformatics Market Is Set To Reach USD 28.6 Billion By 2030 With CAGR Of 13.73% | Marketdigits

(MENAFN– GlobeNewsWire – Nasdaq) The Global Bioinformatics Market was valued USD 10.23 Billion in 2023 and projected to reach USD 28.6 Billion by 2030, growing at a CAGR of 13.73% during the forecast period of 2023-2030 Richmond, Feb. 09, 2024 (GLOBE NEWSWIRE) — According to a research report ” Bioinformatics…

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Functional genomic screening in Komagataella phaffii enabled by high-activity CRISPR-Cas9 library

Abstract CRISPR-based high-throughput genome-wide loss-of function screens are a valuable approach to functional genetics and strain engineering. The yeast Komagataella phaffii is a host of particular interest in the biopharmaceutical industry and as a metabolic engineering host for proteins and metabolites. Here, we design and validate a highly active 6-fold…

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UMI workflow resulting in bams with empty reads

Hello all, In my NGS workflow for UMI based reads, I first tried identifying and removing sequence adapters using bbmerge and cutcadapt: BBMERGE -Xmx1g -ignorejunk in1=SAMPLE_R1 in2=SAMPLE_R2 outa= adapters.fa itn CUTADAPT -a forward_adapter -A reverse_adapter -o s_2_1_sequence_trimmed_UN.fastq.gz -p s_2_2_sequence_trimmed_UN.fastq.gz SAMPLE_R1 SAMPLE_R2 Then, I converted the trimmed fastq files to an…

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Database Of Space Life Science Investigations And Bioinformatics Of Microbiology In Extreme Environments

Database Of Space Life Science Investigations And Bioinformatics Of Microbiology In Extreme Environments Biological experiments performed in space crafts like space stations, space shuttles, and recoverable satellites has enabled extensive spaceflight life investigations (SLIs). In particular, SLIs have revealed distinguished space effects on microbial growth, survival, metabolite production, biofilm formation,…

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2024 Ggplot axis labels

Plot Titles, Axes and Legend Titles. One way to modify plot titles, axes and legend titles is through the labs() function in ggplot2.In order to add math notation to those labels, we can use the expression() function to specify the label text. For example, if we wanted to modify the…

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Shionogi Announces New Phase 3 Data Showing Early Resolution of Many Common COVID-19 Symptoms in JAMA Network Open

OSAKA, Japan–(BUSINESS WIRE)– Shionogi & Co., Ltd. (Head Office: Osaka, Japan; Chief Executive Officer: Isao Teshirogi, Ph.D.; hereafter “Shionogi”) announced the first peer-reviewed publication of the Phase 3 portion of its pivotal, double-blind, randomized, placebo-controlled Phase 2/3 study (SCORPIO-SR) in patients with mild to moderate COVID-19 in Japan, South Korea…

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KEGG T30512: 29135

KEGG T30512: 29135     T30512 (Metagenome): 29135 Help Entry 29135             CDS       T30512                                  Symbol fbp Name fructose-1,6-bisphosphatase class 1   KO Best hit Taxonomy Gammaproteobacteria – Others [GN:hin]Taxonomy Pathway 00010   Glycolysis / Gluconeogenesis 00030   Pentose phosphate pathway 00051   Fructose and mannose metabolism 00680   Methane metabolism 00710   Carbon fixation in photosynthetic organisms 01100   Metabolic pathways…

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Master Continuous Control with DDPG

Master Continuous Control with DDPG | PyTorch Tutorial Table of Contents: Introduction Understanding Deep Deterministic Policy Gradients (DDPG) The Lunar Lander Environment Implementing a Deterministic Policy Gradient Agent 4.1. Importing the Required Libraries 4.2. Initializing the Agent 4.3. Implementing the Actor Network 4.4. Implementing the Critic Network 4.5. Implementing the…

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Pacritinib Shows Transfusion Independence Benefits in Myelofibrosis

Bart Scott, MD Professor, Transplantation Program Clinical Research Division Miklos Kohary and Natalia Zimonyi Kohary Endowed Chair Fred Hutchinson Cancer Center Seattle, WA Targeted Oncology: Could you summarize the approved Janus kinase (JAK) inhibitors for patients with myelofibrosis? BART SCOTT, MD: Ruxolitinib (Jakafi) was approved in 2011, fedratinib (Inrebic) in…

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Generative AI with Google Cloud: Build with AI today

Dive into the exciting world of Generative AI (Gen AI) from Google – the revolutionary technology behind cutting-edge text, image, and code generation tools. This workshop will demystify Gen AI concepts, explore its real-world applications, and provide a foundation for harnessing its potential. Join us for a 4-hour virtual event….

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Scientists Discover Novel Mechanism for Mitochondrial DNA Disposal, Offering Potential for Targeted Therapeutics

In a groundbreaking study, researchers from the Salk Institute and the University of California San Diego have identified a new pathway used by cells to remove dysfunctional mitochondrial DNA (mtDNA) from within mitochondria. The discovery sheds light on how misplaced mtDNA triggers an immune response that promotes inflammation, opening up…

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Placer County cold case gets big break thanks to advanced DNA technology identifying remains

Placer County cold case gets big break thanks to advanced DNA technology Placer County cold case gets big break thanks to advanced DNA technology 02:13 APPLEGATE — A Placer County cold case just got a big break thanks to advanced DNA technology identifying a woman nearly 40 years after her…

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Ubuntu Manpage: mothur – sequence analysis suite for research on microbiota

Provided by: mothur_1.48.0-2_amd64 NAME mothur – sequence analysis suite for research on microbiota SYNOPSIS mothur [ batchfile ] DESCRIPTION This manual page documents briefly the mothur command. Mothur seeks to develop a single piece of open-source, expandable software to fill the bioinformatics needs of the microbial ecology community. It has…

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gmx rotacf – GROMACS 2024 documentation

Description# gmx rotacf calculates the rotational correlation function for molecules. Atom triplets (i,j,k) must be given in the index file, defining two vectors ij and jk. The rotational ACF is calculated as the autocorrelation function of the vector n = ij x jk, i.e. the cross product of the two…

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Bioconductor – MCRestimate

DOI: 10.18129/B9.bioc.MCRestimate     Misclassification error estimation with cross-validation Bioconductor version: Release (3.6) This package includes a function for combining preprocessing and classification methods to calculate misclassification errors Author: Marc Johannes, Markus Ruschhaupt, Holger Froehlich, Ulrich Mansmann, Andreas Buness, Patrick Warnat, Wolfgang Huber, Axel Benner, Tim Beissbarth Maintainer: Marc Johannes…

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Topic Modelling with LDA: A Comprehensive Guide for Students

2/8/24, 5:59 PMtopic-modelling-lda.ipynb – Colaboratory 1/5# This Python 3 environment comes with many helpful analytics libraries installed # It is defined by the kaggle/python Docker image: # For example, here’s several helpful packages to load import numpy as np # linear algebra import pandas as pd # data processing, CSV…

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Biotechnology, Biomedical, Biochemistry, Bioinformatics, Microbiology Freshers Jobs in Chennai | Abiramapuram, Chennai

Job Details LocalitiesAbiramapuram, MKB Nagar, MR Nagar, MRC Nagar, Madambakkam Job ID368762395 RoleNurse Hiring Company NameAchievers Spot Max Experience1 Min Experience0 Description Medical Coding JobsMedical Coding is the process of conversion of text information related to healthcare services intonumeric Diagnosis (Medical Problems) and Procedure (Treatments) Codes using ICD-10 CM andCPT…

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King’s College London hiring Research Associate in Translational Bioinformatics in London, England, United Kingdom

Job DescriptionThis is a Pre-Fellowship for early career researchers wanting to establish a career in MND translational research and become MND research leaders of the future. The postholder will have a leading role in an exciting new project funded by Motor Neurone Disease Association and MND Scotland. The project is…

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CRISPR/Cas9 are the Most Sought Genome Editing Tools

Company Logo Global Genome Editing Market Global Genome Editing Market Dublin, Feb. 09, 2024 (GLOBE NEWSWIRE) — The “Global Genome Editing Market, 2023-2035: Focus on Technology, Industry Trends and Forecasts” report has been added to ResearchAndMarkets.com‘s offering. The global genome editing market size for technologies is estimated to be worth…

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Different relatedness estimates by PLINK and VCFTOOLS despite same method

According to the vcftools manual, specifying the “–relatedness2” flag allows calculating relatedness statistics using the method by Manichaikul et al., BIOINFORMATICS 2010 (doi:10.1093/bioinformatics/btq559). That is, based on KING. According to the PLINK manual, PLINK uses the same method to calculate relatedness when specifying the flag “–make-king-table”. So, although both PLINK…

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Searching For Giant Exoplanets Around M-dwarf Stars (GEMS) I: Survey Motivation

Green triangles show an estimate of the heavyelement content (MZ ) of GEMS from planetary interior models (Thorngren et al. 2016) compared to the Class II disk dust mass (Md) estimates as orange squares (Manara et al. 2022) and the median (and 1-σ) trend seen in the Lupus sample (Ansdell…

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r – ggplot2 legend not appearing

The @benson23 answer is correct, if you want more control you can use manual scales for different aesthetics. If you use linetype in aes instead of fill, you will get a legend as above, if you like that more. library(tidyverse) df <- tribble( ~ tree, ~ o18, “A”, 15, “A”,…

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UV Radiation and Its Impact on Plant Genome: Insights and Mechanisms

UV Radiation and Its Impact on Plant Genome Plants, as primary producers, rely on solar energy for photosynthesis, a vital process for their survival and growth. However, the UV component of solar radiation can impair genome stability in plants by creating DNA lesions known as UV photoproducts. These lesions hinder…

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Deploying OpenAPI Helm Chart on AWS EKS

To deploy the OpenAPI Helm chart on AWS Elastic Kubernetes Service (EKS), we’ll follow these steps: Create an EKS cluster. Configure Kubeconfig to interact with your cluster. Use the Pulumi Kubernetes provider to deploy the OpenAPI Helm chart using kubernetes.helm.v3.Chart. Before we begin, ensure you have the following prerequisites in…

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r – The optimal the Stack size for Rstudio on a Windows OS;

This question was caused by a typo or a problem that can no longer be reproduced. While similar questions may be on-topic here, this one was resolved in a way less likely to help future readers. What would be the optimal the Stack size for Rstudio (on a Windows OS)…

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Shionogi & Co., Ltd. Announces New Phase 3 Data Showing Early Resolution of Many Common COVID-19 Symptoms in JAMA Network Open -February 09, 2024 at 11:00 am EST

Shionogi & Co., Ltd. announced the first peer-reviewed publication of the Phase 3 portion of its pivotal, double-blind, randomized, placebo-controlled Phase 2/3 study (SCORPIO-SR) in patients with mild to moderate COVID-19 in Japan, South Korea and Vietnam in JAMA Network Open. The trial met its primary and key secondary endpoints,…

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A Benchmark of Genetic Variant Calling Pipelines Using Metagenomic Short-Read Sequencing

Introduction Short-read metagenomic sequencing is the technique most widely used to explore the natural habitat of millions of bacteria. In comparison with 16S rRNA sequencing, shotgun metagenomic sequencing (MGS) provides sequence information of the whole genomes, which can be used to identify different genes present in an individual bacterium and…

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Fedora 39 update for mbedtls

This security bulletin contains information about 2 vulnerabilities. EUVDB-ID: #VU86233 Risk: Medium CVSSv3.1: 5.1 [CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:C/C:L/I:N/A:N/E:U/RL:O/RC:C] CVE-ID: CVE-2024-23170 CWE-ID: CWE-385 – Covert Timing Channel Exploit availability: No Description The vulnerability allows a remote attacker to perform MitM attack. The vulnerability exists due to a timing side channel in RSA private operations….

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calculated an LD matrix for a locus using plink2

Hi Everyone, I have a genotype file in  .pgen  format, that I subset and would like to calculate LD Matrix for. Previously I used a .bed file format and use plink 1.9 which worked as charm. But unfortunately my file is in Pgen format which is not supported  in plink…

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Coding Softmax in PyTorch with Triton

Coding Softmax in PyTorch with Triton Introduction Setting up the VS Code Editor Importing Libraries Creating a Sample Tensor Coding Softmax in PyTorch Understanding the Softmax Function Implementing Naive Softmax testing the Softmax Functions Comparing Results in PyTorch and Triton Conclusion In this article, we will explore the concept of…

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Full 16S and 23S rRNA gene-based,strain-level resolution of the microbiota of a mock bacterial microbiome using ONT nanopore sequencing

%PDF-1.5 % 367 0 obj <> endobj 501 0 obj <>stream application/pdf Full 16S and 23S rRNA gene-based,strain-level resolution of the microbiota of a mock bacterial microbiome using ONT nanopore sequencing 2024-02-08T06:26:05Z LaTeX with hyperref 2024-02-09T16:16:08-08:00 2024-02-09T16:16:08-08:00 pdfTeX-1.40.25 False This is pdfTeX, Version 3.141592653-2.6-1.40.25 (TeX Live 2023) kpathsea version 6.3.5 uuid:78a87c92-1dd2-11b2-0a00-a90927fd5800…

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Unmet Needs in Bispecific Therapy Access

This is a video synopsis/summary of a Practice Pearls involving Zahra Mahmoudjafari, PharmD, MBA, BCOP, FHOPA; Robert Mancini, PharmD; and Amir Ali, PharmD, BCOP, FHOPA. In this segment, Mahmoudjafari and Ali discuss the unmet needs and educational aspects related to the use of bispecifics in community oncology. Ali emphasizes the…

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Faulty DNA Disposal System Causes Inflammation

Endosomes (magenta) collect around mitochondria (blue) after infection with virus HSV-1, which attacks mtDNA (green) and causes its release. Credit: Salk Institute One of the ways our cells respond to damage and infection is with what’s known as the innate immune system. While the innate immune response is the first…

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Google Cloud Platform AI Engineer – Volto Consulting

Summary: We are seeking an experienced and passionate Google Cloud Platform AI Engineer to join our team and drive innovation through the application of artificial intelligence solutions on the Google Cloud Platform (Google Cloud Platform). The ideal candidate will have a strong understanding of AI principles, cloud computing, and a…

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Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal

Mitochondrial DNA (mtDNA) encodes essential subunits of the oxidative phosphorylation system, but is also a major damage-associated molecular pattern (DAMP) that engages innate immune sensors when released into the cytoplasm, outside of cells or into circulation. As a DAMP, mtDNA not only contributes to anti-viral resistance, but also causes pathogenic…

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Red Genes: Assessing WuXi AppTec’s Ties to the Party-Army-State

Executive Summary: WuXi AppTec, a major Chinese biotechnology and pharmaceutical firm, claimed that the company has not, does not, and will not pose a national security risk to any country in response to new legislation introduced in the US Congress. The company’s claims are undermined by WuXi Apptec’s network of…

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gmx solvate – GROMACS 2023.4 documentation

Description gmx solvate can do one of 2 things: 1) Generate a box of solvent. Specify -cs and -box. Or specify -cs and -cp with a structure file with a box, but without atoms. 2) Solvate a solute configuration, e.g. a protein, in a bath of solvent molecules. Specify -cp…

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Bioconductor – genomation

DOI: 10.18129/B9.bioc.genomation     Summary, annotation and visualization of genomic data Bioconductor version: Release (3.6) A package for summary and annotation of genomic intervals. Users can visualize and quantify genomic intervals over pre-defined functional regions, such as promoters, exons, introns, etc. The genomic intervals represent regions with a defined chromosome…

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Aurobindo Pharma Freshers Job – Biotech & Microbiology Apply

–Must See– Aurobindo Pharma Freshers Job – Biotech & Microbiology Apply AUROBINDO HIRING We are looking Candidates for our Greenfield project LYFIUS PHARMA PRIVATE LIMITED (100% subsidiary of Aurobindo Pharma Limited) to fill the following Positions in API Division for Kakinada, Andhra Pradesh, India. Fermentation – Microbiologist Qualification: B.Sc/M.Sc /…

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Post-Doctoral in Genomics and Bioinformatics (8991) job with Mohammed VI Polytechnic University

Mohammed VI Polytechnic University is an institution dedicated to research and innovation in Africa and aims to position itself among world-renowned universities in its fields The University is engaged in economic and human development and puts research and innovation at the forefront of African development. A mechanism that enables it…

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All Roads Lead to Genome Editing

Shondra Pruett-Miller, a biochemist at St. Jude Children’s Research Hospital, found her calling during her first year of graduate school at the University of Texas, Southwestern. In 2003, during the departmental faculty research talks, she watched with excitement as Matthew Porteus, now a biochemist at Stanford University, presented his research…

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Sequence alignment matrix

Sequence alignment matrix 2 Hi there, I’m searching for a sequence alignment tool that can provide me with a matrix like the one on the attached image. I need the 4 parameters Identity(%), Homologs (identical + conserved + weakly conserved), Unconserved and Coverage for all combinations AB, AC, CB etc….

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Professor of Medical Bioinformatics and Statistical Genetics job with Aarhus University (AU)

The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Professor in the field of Medical Bioinformatics and Statistical Genetics as per 1 July 2024 or as soon as possible thereafter. The position is a time-limited full-time position for 5 years with extension…

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Create Box Plots in R using Plotly and ggplot2: Step-by-Step

Box Plots Using plotly library(plotly) # data sample data <- c(1, 2, 2, 3, 3, 3, 4, 4, 4, 4, 5, 5, 5, 5, 5) plot_ly(y = data, type = “box”) This code creates a box plot of the data provided in the data variable. You can further customize the…

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LORAX-seq Unveils Backtracking as a New Form of Genetic Regulation

In a groundbreaking development, researchers from NYU Grossman School of Medicine have unveiled a novel technique called Long Range Cleavage sequencing (LORAX-seq). This innovative method can pinpoint the start and end of backtracking events in genetic material, offering unprecedented insights into the intricate world of genetics. Unraveling the Mysteries of…

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Demystifying Open API and OpenAPI

Demystifying Open API and OpenAPI Table of Contents Introduction Understanding APIs Open APIs: An Overview Different Levels of API Openness The Importance of Composable Architecture The Role of API Management The Evolution of API Management Solutions Open API: A Standardized Format The Benefits of Open API Open API in Practice…

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Solved You are conducting a project for RDA examining

You are conducting a project for RDA examining whether stress levels change depending on what participants listen to while studying material. You randomly assign half your participants to listen to white noise while studying material for a test, while the other half listen to nature sounds while studying the material…

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rPFS and cPFS May Act as Surrogate OS End Points in Phase 3 mHSPC Clinical Trials

Both radiographic progression-free survival (rPFS) and clinical PFS (cPFS) appear to be valid surrogates for overall survival (OS) in phase 3 clinical trials evaluating testosterone suppression–based treatment strategies for patients with metastatic hormone-sensitive prostate cancer (mHSPC), according to findings from a study that were published in the Journal of Clinical…

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KEGG T30512: 12494

KEGG T30512: 12494     T30512 (Metagenome): 12494 Help Entry 12494             CDS       T30512                                  Name pyruvate dehydrogenase subunit E1   KO Best hit Taxonomy Actinobacteria [GN:acq]Taxonomy Pathway 00010   Glycolysis / Gluconeogenesis 00020   Citrate cycle (TCA cycle) 00620   Pyruvate metabolism 01100   Metabolic pathways 01110   Biosynthesis of secondary metabolites 01120   Microbial metabolism in diverse environments 01200   Carbon…

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Building Image with openssl – Installing and Using OpenWrt

Termy February 8, 2024, 10:59am 1 Hi there,i’m finally coming around to update to 23.05 and just want to make sure to not F* up something I want to keep TLS1.3 and thus openSSL. Of course, the image build fails if i just include libustream-openssl.It build successfully if i also…

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PCA from plink2 for SGDP using a pangenome and DeepVariant

Hi there, I’m doing my first experiments with PCA and UMAP as dimensionality reductions to visualize a dataset I’ve been working on. Basically, I used the samples from the SGDP which I then mapped on the human pangenome for, finally, calling small variants with DeepVariant. I moved on with some…

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SGRNA Requirement (pdf) – Course Sidekick

PROJECT TITLE: AN IMPROVED DEEP LEARNING METHOD TO PREDICT THE ABILITY OF SGRNA OFF-TARGET PROPENSITY Download all the required/available files from gdrive (3.5MB): drive.google.com/drive/folders/1rDPcagh_iWWV1W9OWdIn8BeVnKdsxWSl?usp=sharing Project Objectives: (a) To review prediction of deep learning method for sgRNA off-target propensity. (b) To model the prediction of sgRNA off-target propensity using CnnCrispr. (c)…

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Mouse Monoclonal Anti-Human Ep-CAM(MX066) Antibody 06931988329125 Medical Device Identification

Primary Device ID 06931988329125 NIH Device Record Key bfd75b79-e4a0-4d75-b31c-b8039e53acd7 Commercial Distribution Status In Commercial Distribution Brand Name Mouse Monoclonal Anti-Human Ep-CAM(MX066) Antibody Version Model Number MAB-0850 10mL Company DUNS 420499410 Company Name Fuzhou Maixin Biotech Co., Ltd. Device Count 1 DM Exempt false Pre-market Exempt true MRI Safety Status Labeling…

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Unlocking PyTorch’s Power: Introducing TorchInductor 2.0

Unlocking PyTorch’s Power: Introducing TorchInductor 2.0 Introduction Principles of Torch Inductor Torch Inductor as PyTorch Native Python First Approach Focus on General Design Technologies Used in Torch Inductor Defined-by-Run Loop Level AR Support for Dynamic Shapes and Strides with Senpai Leveraging the Triton Language Understanding Mine by Run Loop Level…

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