Human Perspectives Question 5001 Mutations in what kind of genes cause the cells

255.Human Perspectives Question 5.003 What happened to mice injected intravenously with an siRNA that targets and destroys Fas mRNA? A)They die. B)They become relatively resistant to the development of fulminant hepatitis. C)They grow less hair. D)They develop virulent fulminant hepatitis. E)Their livers enlarge. Ans: B Difficulty: Medium Human Perspectives 256.Human…

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Just adding the full trace that sage produces

Package: sagemath Version: 9.5-6 Followup-For: Bug #1052051 X-Debbugs-Cc: jordi.burguet.cast…@gmail.com Dear Maintainer, When running sage, there is an ImportError related to libsingular- Singular-4.3.1.so (full trace below). From what I can see, python3-sage depends on libsingular4m3n0: $ apt depends python3-sage | grep libsingular Depends: libsingular4m3n0 (>= 1:4.3.1-p3+ds) Depends: libsingular4-dev (>= 1:4.2.1-p2+ds-3) but…

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[Latest Report] Food Authentication Testing Market 2023 Business Insights and Furure PlanningEurofins, Intertek, SGS, Merieux NutriSciences, EMSL Analytical, NSF, SCIEX, Thermo Fischer Scientific, LGC, RSSL, Campden BRI

The latest report, Global “Food Authentication Testing” Market Trends and Insights, is now accessible on Orbisresearch.com. This research report presents a comprehensive analysis of the Food Authentication Testing market, encompassing key aspects such as COVID-19 impact, market outlook, category, type, application, and end-user outlook. The report delves into the key…

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Bacterial Diagnostics in Aquaculture Market Latest Trends and Future Aspect Analysis

PRESS RELEASE Published September 22, 2023 InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the “Global Bacterial Diagnostics in Aquaculture Market– (By Animal Type (Mackerel, Carps, Milkfish, Sea Bream, Sea Bass, Trout, Crustaceans, And Other Species), By Technique (Histopathology, Electron Microscopy, Scanning Electron Microscopy, Transmission…

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Solved Problem G – PyTorch FROM RESEARCH TO PRODUCTION KEY

Transcribed image text: Problem G – PyTorch FROM RESEARCH TO PRODUCTION KEY FEATURES \& CAPABILITIES Project 2 List of Problems Python Libraries are a set of useful functions that eliminate the need for writing codes from scratch. There are over 137,000 python libraries present today. Python libraries play a…

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Index of /~birch/birchhomedir/dat/tGDE/GDEHELP-solaris-amd64/local/java/seahawk/com/hp/hpl/jena/util/iterator

Name Last modified Size Description Parent Directory   –   ClosableIterator.class 2009-08-28 15:16 191   ExtendedIterator.class 2009-08-28 15:16 674   Filter$1.class 2009-08-28 15:16 737   Filter$2.class 2009-08-28 15:16 946   Filter.class 2009-08-28 15:16 1.1K   FilterIterator.class 2009-08-28 15:16 1.4K   FilterKeepIterator.class 2009-08-28 15:16 741   Map1.class 2009-08-28 15:16 175  …

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At Climate Week, Fashion Needs a Circular ‘Mindshift’

Climate Week running Sept. 17-24 in New York City and led by the Climate Group and the U.N. General Assembly attracted royal attention this week. Prince William announced the finalists for the 2023 Earthshot Prize, an initiative he launched three years ago to scale environmental solutions. Five 1-million-pound ($1.2 million)…

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[Bug 2240302] Review Request: gloo

bugzilla.redhat.com/show_bug.cgi?id=2240302 Tom Rix <trix@xxxxxxxxxx> changed: What |Removed |Added —————————————————————————- Blocks| |1011110 (ML-SIG) Flags| |fedora-review? Referenced Bugs: bugzilla.redhat.com/show_bug.cgi?id=1011110 [Bug 1011110] Machine Learning SIG – review tracker — You are receiving this mail because: You are always notified about changes to this product and component You are on the CC list for…

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Suaeda Glauca Genome Sequence Reveals Halophyte Salt Tolerance

Recently, a research paper titled “Chromosome-scale genome sequence of Suaeda glauca sheds light on salt stress tolerance in halophytes“, completed by Professor Qin Yuan’s team from the Center for Genomics, Haixia Institute of Science and Technology (Future Technology College) at Fujian Agriculture and Forestry University, has been published in the…

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Study provides insights into human 8-cell-like cells and early embryonic development

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some extent in mice, human EGA remains largely unexplored, mainly due to the lack of novel in vitro cell models…

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North West, Walter Sisulu Universities make strides in the battle against TB

North West and Walter Sisulu Universities are making significant strides in the battle against tuberculosis. The two Institutions of Higher Learning unveiled the results of their pre-clinical trials for a groundbreaking combination DNA vaccine against tuberculosis and COVID-19. A month ago, the animal model trials were completed, with positive outcoming…

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Vivek Agnihotri shares glimpse of Raima Sen’s journalist character whom ‘you will love to hate’

Vivek Agnihotri shares a glimpse of Raima Sen’s role as a journalist in The Vaccine War. As The Vaccine War nears its release, Vivek Agnihotri is adding to the excitement of the audience by unveiling a glimpse of different roles in the movie. Recently, the filmmaker shared a glimpse of…

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DNA-bridging by an archaeal histone variant via a unique tetramerisation interface

Chromatin isolation and MNase digestion M. jannaschii DSM 2661 cells were grown in 100 l fermenters in minimal medium containing 0.3 mM K2HPO4, 0.4 mM KH2PO4, 3.6 mM KCl, 0.4 M NaCl, 10 mM NaHCO3, 2.5 mM CaCl2, 38 mM MgCl2, 22 mM NH4Cl, 31 µM Fe(NH4)2(SO4)2, 1 mM C6H9NO6, 1.2 µM MgSO4, 0.4 mM CuSO4, 0.3 µM MnSO4, 36 nM FeSO4, 36 nM CoSO4, 3.5 nM…

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High-Throughput Sequencing Technology Market Analysis, Research Study with Top Key Players by 2029

The qualitative report published by Market Insights Reports research on the “High-Throughput Sequencing Technology Market offers an in-depth examination of the current trends, latest expansions, conditions, market size, various drivers, limitations, and key players along with their profile details. The High-Throughput Sequencing Technology market report offers the historical data for…

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Q1 2024 EPS Estimates for Myriad Genetics, Inc. Reduced by Leerink Partnrs (NASDAQ:MYGN)

Myriad Genetics, Inc. (NASDAQ:MYGN – Free Report) – Stock analysts at Leerink Partnrs lowered their Q1 2024 earnings per share estimates for shares of Myriad Genetics in a report released on Wednesday, September 20th. Leerink Partnrs analyst P. Souda now anticipates that the company will earn ($0.15) per share for…

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capTEs enables locus-specific dissection of transcriptional outputs from reference and nonreference transposable elements

Cell culture All cell lines were grown in 6 cm dishes at 37 °C in a 5% CO2 incubator. The K562, MDA-MB-231 and HCT 116 cell lines were cultured in high-glucose DMEM supplemented with 10% fetal bovine serum and 1% penicillin-streptomycin antibiotics (pen-strep). NCM460 cells were cultured in RPMI 1640 medium supplemented…

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Inhibition of PLK4 remodels histone methylation and activates immune response via cGAS-STING pathway in TP53 mutated AML | Blood

Citation Cheuk Him Man, Wing Lam, Chee Chean Dang, Xiao-yuan Zeng, Li-Chuan Zheng, Natalie Nok-Man Chan, Nelson K. L. Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing Yan Leung, Michael Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Susumu Goyama, Mark Robert Bray, Tak Wah Mak, Anskar…

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Metabolic plasticity of serine metabolism is crucial for cGAS/STING-signalling and innate immune response to viral infections in the gut

Abstract Inflammatory bowel diseases (IBD) are characterized by chronic relapsing inflammation of the gastrointestinal tract. While the association between endoplasmic reticulum (ER) stress and intestinal inflammation is widely accepted, the metabolic consequences of chronic ER-stress on the pathophysiology of IBD remain unclear. By using in vitro, ex vivo, in vivo…

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New function for “STING” signal! Shanghai Jiao Tong University team reveals STING signaling drives new development of NK cell anti-tumor immunity

Introduction: Natural killer (NK) cells are cytotoxic innate lymphocytes that eradicate tumor cells. The induction of durable anti-tumor immune responses by NK cells is a priority for cancer immunotherapy. Although cytosolic DNA sensing plays a crucial role in initiating anti-tumor immunity, the role of NK cell-intrinsic STING signaling is unclear….

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convert github code to colab or kaggle notebook with minor modifications — 2

BUDGET IS FIXED. DONT WASTE YOUR TIME QUOTING IF YOU GONNA BID MORE. I am in search of a freelancer with the capability to transform my existing code, available on GitHub at the following link: [login to view URL], into either a Colab or Kaggle notebook. The existing code is…

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Bioinformatics Expert – Tertiary Analysis at SOPHiA GENETICS

We believe there is a smarter, more data-driven way to make decisions in health. As we pass 1,000,000 genomic profiles analyzed and look to the future of our platform, we are now searching for a Bioinformatics Expert who will be be part of a dynamic and exciting international team. Our…

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Composition and Regulatory Mechanism of the Nucleolar Vacuole in C. elegans

Researchers from the University of Science and Technology (USTC) of the Chinese Academy of Sciences (CAS) have made a significant discovery about the composition and regulatory mechanism of the nuclear vacuole in the model organism C. elegans. The findings, published in Cell Reports, shed light on the structure and function…

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Researchers reveal composition and regulatory mechanism of the nucleolar vacuole in C. elegans

Credit: Cell Reports (2023). DOI: 10.1016/j.celrep.2023.112915 A team led by Prof. Guang Shouhong and Prof. Feng Xuezhu from the University of Science and Technology (USTC) of the Chinese Academy of Sciences (CAS) revealed, for the first time, the composition and regulatory mechanism of the nuclear vacuole in C. elegans. The…

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How do Atoms Move in an Electric Potential

Hi All, I had a theoretical question regarding the electric potential that is applied in CP2K. Let’s say that a simulation box has a electric potential gradient applied to it in the +x-direction: electric potential gradient = 2X If you have positively charged ions (cations) and negatively charged ions (anions),…

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cancel local run in azureml sdk2

This code is creating a local run with sdk2, and I want to cancel this job, how can I do this? #import required libraries from azure.ai.ml import MLClient, command from azure.ai.ml.entities import Environment from azure.identity import DefaultAzureCredential #connect to the workspace ml_client = MLClient.from_config(DefaultAzureCredential()) # set up pytorch environment env…

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Solved Which of the following is a characteristic common to

Transcribed image text: Which of the following is a characteristic common to all ribosomes from organisms of the three domains of life? Ribosomes from organisms of the three domains can be found on the surface of the rough endoplasmic reticulum. Ribosomes from organisms of the three domains contain proteins and…

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slurm – I am trying to create an oci container bundle

slurm.schedmd.com/containers.html&#8217; I plan to proceed by referring to the site above. Configure a bundle for runtime to execute If you run it on a remote node, an error message appears as follows. enter image description here The execution node has an oci bundle image. Why does an error occur? thanks…

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Bioconductor – inveRsion

DOI: 10.18129/B9.bioc.inveRsion     This package is for version 3.7 of Bioconductor; for the stable, up-to-date release version, see inveRsion. Inversions in genotype data Bioconductor version: 3.7 Package to find genetic inversions in genotype (SNP array) data. Author: Alejandro Caceres Maintainer: Alejandro Caceres <acaceres at creal.cat> Citation (from within R,…

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Bioconductor – scPCA

DOI: 10.18129/B9.bioc.scPCA   Sparse Contrastive Principal Component Analysis Bioconductor version: Release (3.17) A toolbox for sparse contrastive principal component analysis (scPCA) of high-dimensional biological data. scPCA combines the stability and interpretability of sparse PCA with contrastive PCA’s ability to disentangle biological signal from unwanted variation through the use of control…

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Google Subsidiaries

From pioneering advancements in advertising like Google AdSense and DoubleClick to shaping the way we interact with technology through Android and Google Chrome, Google’s subsidiaries span a broad spectrum of industries. These subsidiaries have become integral to modern life, enhancing connectivity, accessibility, and productivity. The company’s ventures extend to cloud-based…

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Getting Started in Machine Learning | by Top Boss | Sep, 2023

Photo by John Schnobrich on Unsplash Machine learning, a rapidly evolving field within artificial intelligence, is opening up a world of opportunities for those who want to shape the future with data-driven insights. If you’re wondering how to embark on a career in machine learning, this article will guide you…

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Genome Editing & Genome Engineering Market Future Trends and Forecasts 2023-2030

PRESS RELEASE Published September 22, 2023 A thorough investigation was conducted in order to provide the most recent information on critical aspects of the Genome Editing & Genome Engineering market. The study includes various market forecasts for revenue, size, CAGR, price, and other significant parameters. While emphasizing the key driving…

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Merck & Co., Inc. Announces Phase 3 Keynote-A39/Ev-302 Trial Met Dual Primary Endpoints of Overall Survival (Os) and Progression-Free Survival in Certain Patients with Previously Untreated Locally Advanced or Metastatic Urothelial Cancer -September 22, 2023 at 06:00 am EDT

Merck & Co., Inc. announced positive topline results from the Phase 3 KEYNOTE-A39 trial (also known as EV-302), which was conducted in collaboration with Seagen and Astellas, evaluating KEYTRUDA, Merck?s anti-PD-1 therapy, in combination with Padcev (enfortumab vedotin-ejfv) versus chemotherapy (gemcitabine plus cisplatin or carboplatin) in patients with previously untreated…

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Marfan Syndrome Market Report 2023-2033

PRESS RELEASE Published September 22, 2023 Market Overview: The 7 major Marfan syndrome markets are expected to exhibit a CAGR of 5.44% during 2023-2033. The report offers a comprehensive analysis of the marfan syndrome market in the United States, EU5 (including Germany, Spain, Italy, France, and the United Kingdom), and…

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Discover in detail the driving factors behind the huge demand for Godrej Ananda Phase 3

INSCMagazine: Get Social! Discover the epitome of luxurious living in the heart of North Bangalore at Godrej Ananda Phase 3, nestled within the picturesque Bagalur region, right within the KIADB Aerospace Park. This exceptional residential haven spans across an expansive 9 acres of prime real estate and offers an impressive…

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SL-scan identifies synthetic lethal interactions in cancer using metabolic networks

Datasets The gene expression data, mutation data, CRISPR, and drug perturbation data sets used in this study were obtained from the Depmap project depmap.org/portal/download/all/. The gene expression data set consists of the log2 transformed transcript per million (TPM) values of 19,221 protein-coding genes from 1406 cell lines across 33 cancer…

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Biotech Breakthroughs: CRISPR And Gene Editing

Biotechnology has ushered in a new era of medical innovation, and at the forefront of this revolution stands CRISPR-Cas9 gene-editing technology. This groundbreaking development in biotechnology has the potential to reshape the landscape of healthcare as we know it. The impact on healthcare and various other fields is profound, offering…

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Solved Enter the following into R studio and answer the

Enter the following into R studio and answer the questions based off the following data. # Two sprinters are attempting to make their countries’ Olympic Team. Their # times in the 100m dash are:# Sprinter 1 9.79, 10.11, 9.99, 10.08, 10.22 (all in seconds)# Sprinter 2 9.61, 10.31, 10.02, 10.38,…

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Bioinformatics analysis of RNA-sequencinig data

I am looking for a bioinformatics expert to assist with the analysis of RNA-sequencing data. The goal of the analysis is to identify differentially expressed genes and detect pathway analysis to gain insights into biological processes. Requirements: – Experience in bioinformatics analysis of RNA-sequencing data – Proficiency in statistical analysis…

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get [PDF] Download Lesser Known Large dsDNA Viruses (Current Topics in Microbiology and – Lesser

Lesser Known Large dsDNA Viruses (Current Topics in Microbiology and Immunology, 328) Read and Download Lesser Known Large dsDNA Viruses (Current Topics in Microbiology and Immunology, 328) Download : Lesser Known Large dsDNA Viruses (Current Topics in Microbiology and Immunology, 328) Read : Lesser Known Large dsDNA Viruses (Current Topics…

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Breast Cancer Detected in Breast Milk Earlier Than in Plasma

Researchers say they have detected breast cancer in circulating tumor DNA (ctDNA) from breast milk, and breast milk may allow for earlier cancer detection than plasma. These results “open up the potential” to use breast milk as a new source for liquid biopsy for breast cancer detection, according to the…

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Additional file 1 of Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer

dataset posted on 2023-09-23, 03:17 authored by Jun Wang, Yanqin Niu, Ming Yang, Lirong Shu, Hongxian Wang, Xiaoqian Wu, Yaqin He, Peng Chen, Guocheng Zhong, Zhixiong Tang, Shasha Zhang, Qianwen Guo, Yun Wang, Li Yu, Deming Gou Additional file 1: Table S1. Summary of patients and samples analyzed in this…

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Why the Ark Invest CEO is an investor to look at

Who is Cathie Wood? Cathie Wood is an investor whose title is synonymous with ARK Investment Management, or ARK Invest, the fund-management firm she co-founded in 2014. ARK’s exchange-traded funds posted spectacular common annual returns by means of early 2021, however since then, the funds have fallen from their highs….

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Genes with promoter and enhancer regions as GTF

Okay, first things first Please I am in hurry and need help Slow down and think again what you are doing. I used MACS Used MACS for what? (BTW, convert SAM to BAM and save some space. Just a suggestion). I’m sure you wanted to find out ChIP enriched regions,…

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prometheus – How to gather webflux client metrics when client is generated by OpenAPI

in our Spring Boot application we are using actuator and integrated prometheus. Now we would like to gather HTTP client metrics. In our scenario we are using OpenAPI specification for defining the rest interfaces. With OpenApi generator the client is generated. For that we are using maven plugin org.openapitools:openapi-generator-maven-plugin:6.0.1 Typically,…

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Probing the deep genetic structure of Africa

image: Namib desert in the southwest of Angola. view more  Credit: © Sandra Oliveira Africa is the birthplace of modern humans and the continent with the highest level of genetic diversity. While ancient DNA studies are revealing some aspects of the genetic structure of Africa before the spread of food production,…

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Whole Genome Sequencing Services | Discovery Life Sciences

Discovery Life Sciences is dedicated to sustaining an inclusive workplace where individuals from diverse backgrounds and perspectives are welcomed and valued. We are expanding our workforce and its diversity to enhance our ability to meet the needs of researchers around the world with unique, innovative solutions. We require all Discovery…

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CEDARS-SINAI Research Bioinformatician III – Applied Genomics, Computation & Translational Core in Los Angeles, CA | 870742028

The Applied Genomics, Computation & Translational Core is looking for a Bioinformatician to join the team! The Cedars-Sinai Applied Genomics, Computation, and Translational Core (AGCT Core) is a fully equipped, innovative genomics facility offering data generation and interpretation for basic science and translational research in next-generation sequencing technologies, including single…

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install SLURM on SUSE Linux Enterprise HPC

I am looking for a freelancer who can assist me in installing SLURM on my SUSE Linux Enterprise 15 operating system. I require the latest stable version of SLURM to be installed. Additionally, I am not sure if I need any additional SLURM plugins or components, so I would appreciate…

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Hugo_Symbol to Entrez ID

Hello, I have Myeloid-Acute Myeloid Leukemia (AML) RNAseq data file data_mrna_seq_rpkm.csv. This file has Hugo_Symbols for all 22,844 genes but not its Entrez IDs. I was able use to two methods in R programming 1) library(org.Hs.eg.db) mapIDs method and 2) biomaRT method to get the entrez_ID of only 16,569 genes…

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Abundant Sulfitobacter marine bacteria protect Emiliania huxleyi algae from pathogenic bacteria

Ramanan R, Kim BH, Cho DH, Oh HM, Kim HS. Algae–bacteria interactions: evolution, ecology and emerging applications. Biotechnol Adv. 2016;34:14–29. Article  CAS  PubMed  Google Scholar  Falkowski PG, Fenchel T, Delong EF. The microbial engines that drive earth’s biogeochemical cycles. Science. 2008;320:1034–9. Article  CAS  PubMed  Google Scholar  Buchan A, LeCleir GR,…

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Backward twice without retain_graph=true where I shouldn’t – autograd

Hi! I’m trying to avoid retain_graph=true, but I can’t figure out where I’m doing an extra backward where I shouldn’t. Could someone please give me some guidance? Below is my code: I’m porting a tensorflow meta-learning algorithm to PyTorch. It’s a variant of MAML so, there is an ‘inner loop’…

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Ninja: build stopped: subcommand failed. note: see declaration of ‘PyDict_GetItem’

Hello community! This is my first post so I apologize if I am doing something wrong. I am running into an issue when trying to build pytorch-1.12.1 from source. I have search the web for a solution but cannot find one. I am not familiar with C++ so this stuff…

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Mysterious Circular RNA Linked to Alzheimer’s and Parkinson’s Diseases

Mysterious Circular RNA Linked to Alzheimer’s and Parkinson’s Diseases   Scientists Uncover Mysterious Circular RNA Linked to Alzheimer’s and Parkinson’s Diseases Researchers have gained new insights into the largely overlooked world of circular RNA (circRNA) in brain cells and its crucial role in diseases like Alzheimer’s and Parkinson’s. In addition…

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Creating molecule file for lammps to simulate molecule deposition via deposit command – LAMMPS General Discussion

Can any one pls guide me through creating a molecule file for lammps deposition. I a constantly facing error stating “invalid header keyword -atoms” The file format is described in detail in the molecule command documentation. You just have to follow it exactly. Also, there are example files to compare…

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Free Kaggle Logo Icon – Download in Glyph Style

Download in SVG, PNG, ICO, ICNS, EPS, AI, and pdf formats Add to collection Animate Previous Use icons as fonts with unicons Get thousands of unicons and easily use them on your websites by just inserting a few lines of code. Download unicons High quality animated icons Grab attention, evoke…

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Broadcast a tensor – nlp

Hello everyone, I have a question about how I can broadcast my tensor. For example, I a tensor X = [1,0,0,1,0] and an embedding as follow: Y = [[0.1992, 0.5196, 0.4954], [0.1224, 0.0704, 0.6504], [0.5171, 0.8013, 0.1156], [0.8703, 0.2654, 0.6088], [0.1722, 0.2609, 0.0734]] And then, I want to convert X…

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Solved “ggplot2” package has a couple of interesting data

Transcribed image text: “ggplot2” package has a couple of interesting data sets, including “mpg”. You can have access to this dataset by typing the following in your R script or console: data_q2 <- ggplot2: :mpg You can also get a glimpse of the data set by typing “?ggplot2::mpg” in your…

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Technology Manager, Bioinformatics job with MACQUARIE UNIVERSITY – SYDNEY AUSTRALIA

Salary Package: HEW Level 8 (from $115,030 to $127,995) per annum plus 17% employer’s superannuation and annual leave loading Appointment Type: Full-time, fixed term for 5 years Location: Macquarie University, Wallumattagal Campus (North Ryde) The Role The Australian Proteome Analysis Facility (APAF) is seeking an expert…

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R Box Plot

A box plot, also known as a box-and-whisker plot, is a data visualization that displays the distribution of a dataset’s summary statistics, including its median, quartiles, and potential outliers. It’s particularly useful for comparing the distribution of multiple datasets and identifying potential skewness or variability. The box plot consists of…

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[slurm-users] Submitting hybrid OpenMPI and OpenMP Jobs

Hello, for this setup it typically helps to disable MPI process binding with “mpirun –bind-to none …” (or similar) so that OpenMP can use all cores. Best, Martin On 22/09/2023 13:57, Selch, Brigitte (FIDD) wrote: > Hello, > > one of our applications need hybrid OpenMPI and OpenMP Job-Submit. > > Only one task…

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[slurm-users] Mismatch between scontrol and sacctmgr ?

Hello again, all! I’m having another issue. It seems there’s something not working correctly with reservations when it comes to accounting. The reservations have been created and are being enforced by Slurm. But “sreport reservation utilization” returns an empty table. I noticed that there’s a mismatch between scontrol and sacctmgr…

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Groundbreaking Research Extracts RNA from Extinct Tasmanian Tiger

Once upon a time, the Australian continent and its adjoining islands were home to an apex predator, the Tasmanian tiger. Also known as the thylacine, this striped, dog-sized carnivorous marsupial subsisted primarily on kangaroos and other similar prey. Sadly, due to human activities, the species is no longer present in…

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Modify the code to take most abundant reads from a cluster and process it.

I have a code that processes the cd-hit-est cluster file. The code looks like this: #!/usr/bin/awk -f />Cluster/{ getline a=$3 b=$3 gsub(/[.]/,””,a) gsub(/[>0-9_.]/,””,b) print a “\n” b } One of the clusters in cluster file looks like this >Cluster 9 0 22nt, >35067_10_CCAATTCACTTGTCCCGCCCCC… * 1 21nt, >2636_236_CCACCACTTGTCCCGCCCCCC… at +/85.71% 2…

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MWIDM hiring Bioinformatics Scientist in Boston, MA

ob Description: Qualifications: Education Minimum Requirement: Ph.D. in Bioinformatics, Biostatistics, Computational biology, Computer Science, Genetics, Immunology, Mathematics, Molecular Biology, Statistics, or related field -or- Masters’ degree in the above disciplines, with 3 years of relevant experience or B.S with 6+years of relevant experience. Required Experience and Skills: Passion to solve…

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A CRISPR-Cas12a-based platform facilitates the detection and serotyping of Streptococcus suis serotype 2

Streptococcus suis is a facultative anaerobic Gram-positive bacterium responsible for substantial economic losses in the worldwide swine industry. It can cause meningitis, septicemia, endocarditis, and sudden death in pigs. The bacterium can colonize the tonsil and nasal cavities of healthy pigs, with single or multiple serotypes possible in an individual…

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How these work?different from github version – distributed

exporttorch.onnx.export(model, im, f, verbose=False, opset_version=opset,training=torch.onnx.TrainingMode.TRAINING if train else torch.onnx.TrainingMode.EVAL,do_constant_folding=not train,input_names=[‘images’],output_names=[‘output’],dynamic_axes={‘images’: {0: ‘batch’, 2: ‘height’, 3: ‘width’}, # shape(1,3,640,640)‘output’: {0: ‘batch’, 1: ‘anchors’} # shape(1,25200,85)} if dynamic else None)objdet import cv2import torchimport numpy as npimport timefrom onnxruntime import InferenceSession from utils import load_classes, preprocess, postprocess, plot_results if name == “main”: #…

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Pytorch dataloader: data shape issue with custom COCO dataset for model finetuning – vision

I have an object detection task for which I prepared images and annotations*. The objective to is fine-tune an existing model with Pytorch. Images (PNGs) are stored in the same folder where the COCO json annotations are stored. The json annotations use the Object Detection COCO format: “info”: {…}, “images”:…

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PyTorch Meetup #16 Tickets, Thu 5 Oct 2023 at 19:00

Details Join us this October 5th for the London PyTorch Meetup #16. About the Event:PyTorch isn’t just another framework; it’s the de-facto standard for Deep Learning. Our community is dedicated to bringing together PyTorch users in London and those with a profound interest in ML and AI. This is your…

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python – Pytorch: Freeze layer and make layer’s gradients as 0’s

What’s the correct way to set a pytorch neural network to be false? (1) In this post: www.cs.toronto.edu/~lczhang/321/lec/input_notes.html, they set model.requires_grad=False. However, when I check for name, param in model.named_parameters(): print(name, param.requires_grad) I got all True. And all param.grad are not 0’s. (2) If I do set param.requires_grad=False, I will…

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FDA Launches Priority Review of Belzutifan for Previously Treated Advanced RCC

FDA Launches Priority Review of Belzutifan for Previously Treated Advanced RCC The FDA has granted priority review to the supplemental new drug application (sNDA) for belzutifan (Welireg). The sNDA seeks approval for the indication of patients with previously treated advanced renal cell carcinoma (RCC) following immune checkpoint and anti-angiogenic therapies.1 The…

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DNA Methylation Controls Verticillium Dahliae’s Virulence in Plants

This study is led by Dr Cheng-Guo Duan (Center of Excellence in Molecular Plant Sciences, Chinese Academy of Science). As a conserved epigenetic mark, DNA cytosine methylation at 5′ position (5-mC) plays important roles in multiple biological processes including plant immunity. While, it remains still elusive about the involvement of…

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Zeidan Recaps the Phase 3 IMerge Trial of Imetelstat in Lower-Risk MDS

Amer Zeidan, MBBS, Yale Cancer Center, discusses the rationale of studying imetelstat in the phase 3 IMerge trial (NCT02598661) in patients with heavily transfusion dependent, non-del(5q) lower-risk myelodysplastic syndrome (MDS) that is relapsed or refractory to erythropoiesis stimulating agents. According to results from the study, response rates with imetelstat were…

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Induced pluripotent stem cells: ex vivo models for human diseases due to mitochondrial DNA mutations | Journal of Biomedical Science

Wallace DC. Mitochondrial genetic medicine. Nat Genet. 2018;50:1642–9. Article  CAS  PubMed  Google Scholar  Nunnari J, Suomalainen A. Mitochondria: in sickness and in health. Cell. 2012;148(6):1145–59. Article  CAS  PubMed  PubMed Central  Google Scholar  Chan DC. Mitochondria: dynamic organelles in disease, aging, and development. Cell. 2006;125(7):1241–52. Article  CAS  PubMed  Google Scholar  Picard…

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Sequencing data of DNA repair substrate plasmid by TMEJ

TMEJ assay in nuclear extracts. The assay was performed as described by Dutta et al. (Dutta et al., 2017) with modifications. Briefly, exponentially growing U2OS cells transiently expressing POLQ-Flag-HA in 60 mm plates (90% confluent) were irradiated with X-rays (10Gy). After indicated time points of incubation, the irradiated and control…

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Global Induced Pluripotent Stem Cells (iPSCs) Market Share [2023-2030]

Global Induced Pluripotent Stem Cells (iPSCs) Market Overview [2023] – Global “Induced Pluripotent Stem Cells (iPSCs) Market” (2023-2030) research report gives the most upcoming industry information on the real market situation and future outlook. This report provides you analysis of the Induced Pluripotent Stem Cells (iPSCs) market size, share, future…

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Phillips Discusses Treatment Options for Early-Relapsed DLBCL

Tycel J. Phillips, MD (MODERATOR) Associate Professor, Division of Lymphoma Department of Hematology & Hematopoietic Cell Transplantation City of Hope Duarte, CA EVENT REGION Maryland; Virginia; Washington, DC PARTICIPANT LIST Xinting Fu, MD | Andrew Pham, MD | David Shin, MD | Sharon Yee, MD | Albert Dekker, MD |…

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Many British health trusts slow to adopt electronic records systems, shows BMJ survey

Many health organizations in England are still reliant on paper patient notes and drug charts, despite progress toward electronic records and prescribing, The BMJ has found. The National Health Service (NHS) says it is investing nearly 2 billion pounds ($2.5 billion) to encourage trusts to adopt electronic patient records (EPRs)….

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Extreme RAM consumption of an md simulation – User discussions

max.m90 September 22, 2023, 4:06pm 1 GROMACS version: 2022.5GROMACS modification: NoI encountered an ‘OUT_OF_MEMORY’ error with the following job details for an md simulation with ~250,000 particles: Nodes: 16Cores per node: 64CPU Utilized: 310-17:42:30CPU Efficiency: 97.49% of 318-17:50:56 core-walltimeJob Wall-clock time: 07:28:14Memory Utilized: 5.31 TB (estimated maximum)Memory Efficiency: 392.86% of…

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Compare peaks between clusters in sc-ATAC

Compare peaks between clusters in sc-ATAC 0 Hi So If you have the called peaks per cluster from sc-ATAC and you want to compare between the annotated regions (promoters, enhancers, introns ..etc) between the clusters. Do you use raw peak counts? Do you run differential peak to background? Do you…

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Merck Says Phase 3 KEYNOTE-A39/EV-302 Trial Meets Dual Primary Endpoints

(RTTNews) – Merck & Co Inc. (MRK), known as MSD outside of the U.S. and Canada, announced Friday positive topline results from the Phase 3 KEYNOTE-A39 trial, which was conducted in collaboration with Seagen Inc. (SGEN) and Astellas Pharma Inc. (ALPMY.PK, ALPMY). The trial evaluated KEYTRUDA, Merck’s anti-PD-1 therapy, in…

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Team Leverages CRISPR-Cas to Simplify, Speed Lab Animal Research

With the new method, the cells in individual organs of animals can be genetically modified in a mosaic-like manner (symbol image generated with Midjourney). Credit: ETH Zurich Key points: Using CRISPR-Cas, researchers have developed a way to simultaneously make several dozen gene changes in the cells of a single animal….

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CAR-T Cell Immunotherapy Market Will Expand At a Consistent CAGR for 2023-2030

Global “CAR-T Cell Immunotherapy Market” (2023-2030) research report finds essential elements of this market in light of present industry, this market requests, business methodologies employed by CAR-T Cell Immunotherapy Market players and therefore the future prospects from different edges intimately. The report considers the revenue generated from the sales of…

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Ties in reranked list

Ties in reranked list 0 I’m trying to perform GSEA with the fgsea package in R: fgseaRes<-fgsea(pathways=pathwaysH,stats=new_res_important) However, I receive the error: Warning message: In preparePathwaysAndStats(pathways, stats, minSize, maxSize, gseaParam, : There are ties in the preranked stats (5.02% of the list). The order of those tied genes will be…

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Sickle Cell Disease Pipeline, Clinical Trials Assessment, FDA Approvals 2023 (Updated)

PRESS RELEASE Published September 22, 2023 DelveInsight’s, “Sickle Cell Disease Pipeline Insights 2023” report provides comprehensive insights about 40+ companies and 50+ pipeline drugs in the Sickle cell disease pipeline landscape. It covers the Sickle Cell Disease pipeline drug profiles, including clinical and nonclinical stage products. It also covers the…

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CHMP issues positive opinion on Adcetris in Hodgkin lymphoma

The Committee for Medicinal Products for Human Use of the European Medicine Agency has adopted a positive opinion for the extension of the marketing authorization of Adcetris (brentuximab vedotin) and recommended its approval in combination with doxorubicin, vinblastine, and dacarbazine—or AVD—in adult patients with previously untreated CD30+ stage 3 Hodgkin…

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Compiling vocabularies of nonoverlapping codons with graph theory and SageMath

The study of frameshift mutations as a biological phenomenon also raises structural-combinatorial questions that go beyond biology alone. They also contain biological sense, but have a purely mathematical or computational solution. In particular, this can be said of the case of (non)overlapping codons – a topic that always arises when…

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Why Only Mom’s Mitochondrial DNA Gets Passed Down, According to a Recent Study

A recent study has shed light on the reason why only maternal mitochondrial DNA (mtDNA) gets passed down to offspring. The mitochondria, which generate energy for cells, are made entirely from a genetic recipe found in the mother’s DNA. The study, conductedresearchers from the US and Spain, sequenced the genes…

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Unmasking the Mystery: Why You Didn’t Inherit Your Dad’s Mitochondria Will Leave You Astonished!

“Unmasking the Mystery: Why You Didn’t Inherit Your Dad’s Mitochondria Will Leave You Astonished!” Why You Didn’t Get Your Dad’s Mitochondria: An Amazing Discovery Have you ever wondered why you inherit your mother’s mitochondria and not your father’s? The answer lies in groundbreaking research that sheds light on the fascinating…

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Net2Source Inc. hiring Associate Bioinformatics Scientist in Cambridge, MA

JOB TITLE: Bioinformatics Scientist – II (Associate) LOCATION: Boston ( 33 Avenue Louis Pasteur, Boston, MA 02115, United States) Cambridge MA (320 Bent St, Cambridge, MA 02141, United States) DURATION: 12 months Note: we need someone experienced with analyzing and interpreting existing pipeline/Dataset (not building pipeline) which is a more…

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Precision RNA base editing with engineered and endogenous effectors

Gray, M. W. Evolutionary origin of RNA editing. Biochemistry 51, 5235–5242 (2012). Article  CAS  PubMed  Google Scholar  Covello, P. & Gray, M. On the evolution of RNA editing. Trends Genet. 9, 265–268 (1993). Article  CAS  PubMed  Google Scholar  Yablonovitch, A. L., Deng, P., Jacobson, D. & Li, J. B. The…

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cluster computing – Snakemake: Handling Preempted Jobs on Slurm: Issues with Job Status and Cleanup

This message follows up on the one posted two years ago (Snakemake: Job preemption can interrupt running jobs on clusters, how to make sure that the task is not considered as failed?). I no longer encounter the described bug (IncompleteFilesException), but I still haven’t managed to handle preempted jobs properly….

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Stream Noamm – Electroporation EP (TGRWDS02) Snippets by Tiger Weeds

published on 2023-09-16T18:05:24Z After making his mark on TWDIG01, the enigmatic artist Noamm from Northern Greece makes his return on Tiger Weeds with a solo 6-track EP. Featuring stripped-down, back-to-basics sound, which truly showcases his mastery of minimalism. Each track has been thoughtfully composed to emphasize the raw and unadulterated…

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Bioinformatics Scientist, Immunology Job – Karkidi

Job Description Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus’ proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical…

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Jobs in South East England

PhD Alert Created Job Alert Created Your PhD alert has been successfully created for this search. Your job alert has been successfully created for this search. Ok Ok jobs.ac.uk Account Required In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account Create Account Create Account Alert Creation…

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DNA vaccine study backs electroporation technology: :: Medtech Insight

Executive Summary Animal trial results for Genetronics Biomedical’s electroporation technique for enhancing the efficacy of DNA vaccines continue to show promise, the San Diego, California firm has reported. In a study performed in collaboration with Chiron, electroporation-enhanced DNA vaccination was found to provide faster, stronger, and longer-lasting antibody and cellular…

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Missed Out on Nvidia’s Incredible Surge? 1 Artificial Intelligence (AI) Stock to Buy Hand Over Fist Before It Joins the $2 Trillion Club.

There has been intense focus on artificial intelligence (AI) in 2023, with a race among companies — big and small — and countries to rapidly deploy and develop applications based on this technology. That’s not surprising since AI is expected to become a crucial driver for the global economy in the…

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Targeting MTHFD1 and MTHFD2 as cancer treatment

Abstract: One-carbon (1C) metabolism provides building blocks for nucleotide synthesis and therefore plays a central role in DNA replication and repair. To sustain rapid proliferation, cancer cells often upregulate their 1C metabolism, including the enzymes MTHFD1 and MTHFD2, as a part of their metabolic rewiring. Previously, MTHFD2 in particular has…

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Solved Use the College data frame included in the ISLR

Use the College data frame included in the ISLR package. In R code use ggplot 2 if needed and help() if needed Generate jittered scatterplots of out-of-state tuition as a function of the percentage of new students who are from the top 10% of their high school classes that are…

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