(Description) Figure 15 The ribosome is organised into a small subunit and a large subunit. It is useful to be aware that the sizes of the subunits and their component ribosomal RNAs (rRNAs) are described by a so-called sedimentation coefficient ‘S’, which depends on their relative molecular mass and shape (S stands for Svedberg unit). The small and large subunits are referred to as 30S and 50S, respectively, for prokaryotic ribosomes; and 40S and 60S, respectively, for eukaryotic ribosomes. The complete ribosome is referred to as 70S for prokaryotic ribosomes and 80S for eukaryotic ribosomes.

This diagram summarises the structural organisation of prokaryotic and eukaryotic ribosomes. Prokaryotic ribosomes are 70S particles comprising a small, 30S subunit and a large, 50S subunit. The 30S subunit is made up of 16S rRNA and 21 proteins; and the 50S subunit is made up of 23S rRNA, 5S rRNA…

Continue Reading (Description) Figure 15 The ribosome is organised into a small subunit and a large subunit. It is useful to be aware that the sizes of the subunits and their component ribosomal RNAs (rRNAs) are described by a so-called sedimentation coefficient ‘S’, which depends on their relative molecular mass and shape (S stands for Svedberg unit). The small and large subunits are referred to as 30S and 50S, respectively, for prokaryotic ribosomes; and 40S and 60S, respectively, for eukaryotic ribosomes. The complete ribosome is referred to as 70S for prokaryotic ribosomes and 80S for eukaryotic ribosomes.

Figure 2 | circRNA TCFL5 Promote Esophageal Cancer Progression by Modulating M2 Macrophage Polarization via the miR-543-FMNL2 Axis

Overexpression of circRNA TCFL5 promotes proliferation, invasion, and migration of Eca109 and KYSE150. (a) qRT-PCR was used to detect whether the expression of circRNA TCFL5 is overexpressed or suppressed Eca109 and KYSE150 cells; (b) CCK-8 analysis was used to detect the proliferation of Eca109 and KYSE150 cells affected by circRNA…

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python – Scikit Learn IsolationForest: How to Fit Multiple Dataframes With Different Parameters (Not Using GridSearchCV)

I have a five separate pandas dataframes that I’ve put inside a dictionary. I want to run five separate IsolationForest models in scikit-learn with different sets of parameters for each model. However, I don’t want to run each model separtely. So my question is, how can I run these models…

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Multiplexed activation in mammalian cells using a split-intein CRISPR/Cas12a based synthetic transcription factor

Multiplexed activation in mammalian cells using a split-intein CRISPR/Cas12a based synthetic transcription factor – Fingerprint — University of Edinburgh Research Explorer Sort by Weight Alphabetically Medicine & Life Sciences Inteins 100% Clustered Regularly Interspaced Short Palindromic Repeats 75% Acidaminococcus 64% Francisella 52% Transcription Factors 49% Cellular Reprogramming 42% Cell Biology…

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Tumorigenicity risk of iPSCs in vivo: nip it in the bud

Review . 2022 Feb 3;5(1):pbac004. doi: 10.1093/pcmedi/pbac004. eCollection 2022 Mar. Affiliations Expand Affiliations 1 Department of Cell Biology, Naval Medical University, Shanghai 200433, China. 2 Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, and Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Southern Medical University,…

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Novartis announces promising five-year data for leukaemia treatment Kymriah

Novartis has shared long-term, five-year follow-up results from its pivotal clinical phase 2 trial, ELIANA, evaluating Kymriah (tisagenlecleucel), the first-ever approved CAR T-cell therapy, in children and young adult patients with relapsed or refractory (r/r) B-cell acute lymphoblastic leukaemia (ALL). Kymriah is a one-off treatment designed to help patients’ immune…

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Maintaining manganese in tumor to activate cGAS-STING pathway evokes a robust abscopal anti-tumor effect.

Affiliation Wang C(1), Sun Z(1), Zhao C(1), Zhang Z(1), Wang H(1), Liu Y(1), Guo Y(1), Zhang B(1), Gu L(2), Yu Y(2), Hu Y(3), Wu J(4).Author information: (1)State Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University, School of Life Sciences, Nanjing University, Nanjing 210093, PR China. (2)State…

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BY3 – YFull YTree Info

J-BY3 – YFull YTree Info SNPs currently defining J-BY3 BY3 / FGC15184     Sample ID Country / Language Info Ref File Testing company Statistics Status YF016315 —— J-FGC15174 J-FGC15174*, J-FGC15168*, J-FT258574 Hg38 .BAM FTDNA (Y500) 23X, 12.0 Mbp, 151 bp YF068400 Sudan (Janūb Kurdufān) J-FGC38453* —— Hg38 .BAM FTDNA (Y700)…

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Index of /~ckern/FAANG_Project/Cattle_NCBI

Name Last modified Size Description Parent Directory   –   Aligned_Reads/ 2016-07-30 04:38 –   Cufflinks_Output/ 2017-11-11 11:53 –   FEELnc/ 2018-08-14 16:03 –   Gene_Expression/ 2016-09-01 14:14 –   Genome/ 2018-04-04 15:54 –   Intermediate_LncRNA.feelncclassifier.log 2016-08-05 15:59 18K   LncRNA/ 2018-08-08 11:07 –   Raw_Reads/ 2016-07-28 15:11 –  …

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TwinEQTL: Ultra Fast and Powerful Association Analysis for eQTL and GWAS in Twin Studies

doi: 10.1093/genetics/iyac088. Online ahead of print. Affiliations Expand Affiliations 1 Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599, USA. 2 Department of Psychiatry, University of North Carolina, Chapel Hill, NC 27599, USA. 3 Department of Psychiatry, University of Utah, Salt Lake City, UT 84108, USA. 4 Gilead…

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Convert ONNX RuntimeError: tin_shift_forward_impl: implementation for device cpu not found.

when convert tin to onnx meet this issue: RuntimeError: tin_shift_forward_impl: implementation for device cpu not found. env:sys.platform: linuxPython: 3.8.10 (default, Jun 2 2021, 10:49:15) [GCC 9.4.0]CUDA available: TrueGPU 0,1: Tesla T4CUDA_HOME: /usr/local/cudaNVCC: Cuda compilation tools, release 11.4, V11.4.120GCC: x86_64-linux-gnu-gcc (Ubuntu 9.3.0-17ubuntu1~20.04) 9.3.0PyTorch: 1.9.1+cu111PyTorch compiling details: PyTorch built with: GCC 7.3…

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Identification of the genetic elements involved in biofilm formation by Salmonella enterica serovar Tennessee using mini-Tn10 mutagenesis and DNA sequencing

doi: 10.1016/j.fm.2022.104043. Epub 2022 Apr 23. Affiliations Expand Affiliations 1 Department of Food Science and Technology, The University of Georgia, 1109 Experiment Street, Griffin, GA, 30223-1797, USA. 2 Department of Food Science and Technology, The University of Georgia, 1109 Experiment Street, Griffin, GA, 30223-1797, USA. Electronic address: jchen@uga.edu. Item in…

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Regions NOT forming single region in region union command – LAMMPS General Discussion

i am trying to simulate a lennard-jones gas in two cubical chambers with a cylindrical tunnel in between them to allow particles to go from on compartment to other. i have used the region union command to join the two blocks and cylinder(open 1 open 2, i mean its open…

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Possessed by the Moon – Review by gasmask_colostomy

About halfway through ‘Possessed by the Wolf’, Gengis Khan suddenly decide to tell us that they are more modern than they were presenting as, dropping a change in riff that heralds the way for heavier, more technical, and more exciting content to come. Until then I had thought these Italians…

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Bioconductor – interacCircos (development version)

DOI: 10.18129/B9.bioc.interacCircos     This is the development version of interacCircos; for the stable release version, see interacCircos. The Generation of Interactive Circos Plot Bioconductor version: Development (3.16) Implement in an efficient approach to display the genomic data, relationship, information in an interactive circular genome(Circos) plot. ‘interacCircos’ are inspired by…

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python – NotFittedError – Titanic Project Kaggle

I am trying different machine learning projects from Kaggle to make myself better. Here is the model that I am using: from sklearn.ensemble import RandomForestClassifier y = train_data[“Survived”] features = [“Pclass”, “Sex”, “SibSp”, “Parch”] X = pd.get_dummies(train_data[features]) X_test = pd.get_dummies(test_data[features]) model = RandomForestClassifier(n_estimators = 100, max_depth = 5, random_state =…

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Multifactor analysis

Multifactor analysis 1 @66dd6104 Last seen 1 day ago United States HI every one I am new to RNA seq analyisis using R. I Am usig DESeq 2 for my analysis. I have four different Samples with three replicates each and I want to compare all of them with control…

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File:Human Dact1 Alphafold structure prediction.png

Summary DescriptionHuman Dact1 Alphafold structure prediction.png English: Using algorithm developed in Jumper, J et al. Highly accurate protein structure prediction with AlphaFold. Nature (2021), predicted the 3D structure of human Dact1. Date 5 December 2021 Source alphafold.ebi.ac.uk/entry/Q9NYF0 Author Jumper, J et al. Highly accurate protein structure prediction with AlphaFold. Nature…

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Austinmillo Blog – NOBOX-5in1 RF EMS Electroporation LED Photon Light…

NOBOX-5in1 RF EMS Electroporation LED Photon Light Therapy Beauty Device Anti Aging Face Lifting Tightening Eye Facial Skin Care Brand Name: foreverlily Material: Plastic Origin: CN(Origin) Power Source: USB Charger Working Principle: LED Working Principle: RF Working Principle: EMS Function: Skin Tightening Function: Facial Clean Function: Skin Rejuvenation Function: Skin Mouisture Function: Dead Skin Removal Function: Anti-acne Function: Blemish Removal Function: Anti… View On WordPress Read…

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Biotechnology Careers

Images for Biotechnology Careers Biotechnology Careers: In-Demand Jobs Shaping Our Future ICAR-NRCB Recruitment 2020 – BSc Microbiology & Biotechnology Job Govt RGCB Research Jobs – Biotechnology & Bioinformatics JRF Position Biotech Jobs | CT19 Biotechnology Job Outlook | A Career in High Demand 9 of the Best Biotechnology Careers For…

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Forage Bioinformatics Master’s student / AAFC

Molecular biology (e.g., DNA and RNA extraction). Rearing of plants in a greenhouse. Sample collection. Bioinformatics related to the assembly and annotation of a reference genome sequence. Work environment The candidate is required to be eligible or be enrolled as a Master’s student in the Department of Plant Sciences at…

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47 Postdoc and Academic Positions at The European Molecular Biology Lab.

47 Postdoc and Academic Positions at The European Molecular Biology Lab. – Ntchito Scholarship Postdoc and Academic Positions at The European Molecular Biology Laboratory (EMBL), a…

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Pathway Enrichment

Pathway Enrichment 0 Is there any tool that can directly give me my gene id in first column and its pathway in second column? i am working with rice gene id. Thanks! KEGG ORA ENRICHMENT PATHWAY • 198 views • link updated 3 hours ago by newbio17 ▴ 350 •…

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Some religious leaders ‘have fuelled’ South Africans’ hesitancy to take Covid-19 vaccines

South Africa Suthentira Govender Senior reporter 11 June 2022 – 09:15 While religious leaders have largely encouraged worshippers to vaccinate against Covid-19, there are some who have used religion to derail SA’s vaccination drive… This article is free to read if you register or sign in. If you have already…

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Bioinformatics Analyst at Dana-Farber Cancer Institute in 450 Brookline Ave, Boston, MA

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate…

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Postdoctoral position in bioinformatics of Evo-Devo

Vous voyez une version de l’annonce optimisée pour les appareils mobiles. Annonce originale Introduction UNIL is a leading international teaching and research institution, with over 5,000 employees and 17,000 students split between its Dorigny campus, CHUV and Epalinges. As an employer, UNIL encourages excellence, individual recognition and responsibility. Presentation The…

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A desirable transgenic strategy using GGTA1 endogenous promoter-mediated knock-in for xenotransplantation model

Lai, L. et al. Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning. Science 295, 1089–1092. doi.org/10.1126/science.1068228 (2002). ADS  CAS  Article  PubMed  Google Scholar  Kuwaki, K. et al. Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat. Med. 11, 29–31. doi.org/10.1038/nm1171 (2005). CAS  Article  PubMed  Google…

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NRPS annotation

NRPS annotation 1 Hi everyone, I want to use NRPSpredictor2 for NRPS analysis and I don’t understand how it works, how to download it? the site mentioned on the article “nrps.informatik.uni-tuebingen.de/” does not work for me! do you have an experience with this package? thank you in advance Rima genome…

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India’s economy rebounded strongly in 2nd half of year

The Indian economy has rebounded strongly despite three significant Covid-19 waves, the US Treasury said in a report to the Congress on Friday. India’s acute second wave weighed heavily on growth through the middle of 2021, delaying its economic recovery, the Treasury said in a semi-annual report. “However,…

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Electroporation Instruments Market 2022 to 2028: Market Value, Trend Analysis & Competition Tracking

“Electroporation Instruments Market Report, 2022 to 2028 Electroporation Instruments Market report provides deep exposure to Electroporation Instruments industry and main market trends. The market research report contains forecast market data, demand, price trends, and company shares of the leading Electroporation Instruments segmentation by geography. The report splits the market size,…

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Senior Scientist – Clinical Bioinformatics and Data Science (m/w/d)

OUR COMPANY At Boehringer Ingelheim we develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company, we focus on long-term performance. We believe that if we have talented and ambitious people who are passionate about innovation, there is no…

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New CRISPR-Based Map Opens Door to New Genetic Testing, Therapeutic Possibilities

Researchers from all around the world have been working on mapping human genes to their functions. Now, for the first time, that mapping has been completed, and it opens the doors for all kinds of genetic testing and medicinal possibilities. In 2003, members of the Human Genome Project completely sequenced…

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Kitchen Helper (m/w/d) in Heidelberg bei Embl European Molecular Biology Laboratory

The EMBL Food Services department comprises 30 staff working in 3 sections, Event catering, Canteen and the Cafeteria.Event catering is currently coordinated by a team of two experienced colleagues. We provide our services to the Courses and Conference office as well as other departments that organise international meetings at the…

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How to identify locus_tag by using RefSeq protein info (WP_*)

How to identify locus_tag by using RefSeq protein info (WP_*) 0 Hi, I would like to know the locus tag of a protein annotated with RefSeq (WP_*). For example, I would like to identify the genomic location of a protein (WP_073031595.1) and also know its adjacent proteins. The GenBank file…

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4basebio Plc – Result of AGM

9 June 2022 4basebio PLC(“4basebio” or the “Company”)Annual General Meeting 2022 (“AGM”) 4basebio Plc (AIM: 4BB), the specialist life sciences group focused on exploiting intellectual property in the field of cell and gene therapies and DNA and mRNA vaccines, announces that all of the resolutions proposed at its Annual General…

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cytoscape – Issue with iCTNet2 installation

Has anyone encountered this same installation issue of iCTNet2? I encountered this issue for installation of iCTNet2 via Cytoscape App Manager and similarly via installation from website download/install page. I tried both installations via Cytoscape and via website takes a long time, when both is still installing even 4 hours…

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SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma

Clapier, C. R., Iwasa, J., Cairns, B. R. & Peterson, C. L. Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes. Nat. Rev. Mol. Cell Biol. 18, 407–422 (2017). CAS  PubMed  PubMed Central  Article  Google Scholar  Mashtalir, N. et al. Modular organization and assembly of SWI/SNF family chromatin remodeling complexes….

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Description, Programming Languages, Similar Projects of ggfx

ggfx is a (currently experimantal) package that allows the use of various filters and shaders on ggplot2 layers. Installation You can install ggfx from CRAN in the usual manner (install.packages(‘ggfx’)) or you can grab the development version directly from github using the devtools package: # install.packages(‘devtools’) devtools::install_github(‘thomasp85/ggfx’) Example The basic…

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R programming language tutorials – Technical Ripon

Are you learning the R programming language? Want to learn how to do more tasks with R? Check out our Do More With R video tutorials below — most with accompanying text articles and code, almost all under 10 minutes. In the table below you can easily search all tutorials…

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python 3.x – PySpark on Jupyterhub K8s || Unable to query data || Class org.apache.hadoop.fs.s3a.S3AFileSystem not found

Pyspark Version: 2.4.5 Hive Version: 1.2 Hadoop Version: 2.7 AWS-SDK Jar: 1.7.4 Hadoop-AWS: 2.7.3 When I am trying to show data I am getting Class org.apache.hadoop.fs.s3a.S3AFileSystem not found while I am passing all the information which all are required. I passed all three for this config fs.s3.aws.credentials.provider org.apache.hadoop.fs.s3a.BasicAWSCredentialsProvider com.amazonaws.auth.InstanceProfileCredentialsProvider com.amazonaws.auth.EnvironmentVariableCredentialsProvider…

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python – ValueError: Unused step method arguments: {‘initvals’} in pymc3

I am trying to use Automated Recommendation Tool which utilizes pymc3 package but I am facing issues while executing the following code cell – %%time if run_art: art = RecommendationEngine(df, **art_params) else: with open(os.path.join(art_params[‘output_directory’], ‘art.pkl’), ‘rb’) as output: art = pickle.load(output) Following is the error that pops up – ValueError…

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Resolved: Is conversion of a function pointer to a uintptr_t / intptr_t invalid?

Question: Microsoft extensions to C and C++: To perform the same cast and also maintain ANSI compatibility, you can cast the function pointer to a uintptr_t before you cast it to a data pointer: int ( * pfunc ) (); int *pdata; pdata = ( int * ) (uintptr_t) pfunc;…

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React Query Codegen from OpenAPI

Rapini is a new tool that can generate custom React Query hooks using OpenAPI (Swagger) files. The Command Line Interface (CLI) tool will take a path to an Open API file and generate a package that includes react hooks, typescript types and axios http requests – and this package is…

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Reporting results from fastp Read GC content

Reporting results from fastp Read GC content 1 Hi, I have some QC results for a Paired end seq before and after filtering (Mouse samples). I am unable to interpret the plot Read GC content and I am not sure if the results are fine in this case. I am…

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73 Boys Enrolled for DMD Therapy Pamrevlumab’s Second Phase 3 Trial

FibroGen has completed patient enrollment for its Phase 3 trial evaluating pamrevlumab in combination with corticosteroids as a potential treatment for children with Duchenne muscular dystrophy (DMD). The LELANTOS-2 study (NCT04632940) has enrolled 73 boys with DMD, ages 6 to 12, who maintain their ability to walk. The trial, the second…

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Metagenomics Sequencing Market Size 2022 Global Industry Revenue, Business Growth, Development Strategy, Trends, Demand and Applications Market Research Report Forecast 2025

Global “Metagenomics Sequencing Market” Research Report 2022 is a historical overview and in-depth study of the current & future market of the Metagenomics Sequencing industry. The report represents a basic overview of the Metagenomics Sequencing market share, and competitor segment with a basic introduction of key players, top regions with…

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Advanced Self-Healing Asphalt Reinforced by Graphene Structures: An Atomistic Insight

Graphene-modified asphalt nanocomposite has shown an advanced self-healing ability compared to pure asphalt. In this protocol, molecular dynamics simulations have been applied in order to understand the role of graphene in the self-healing process and to explore the self-healing mechanism of asphalt components from the atomistic level. This method can…

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RCSB PDB – 7SBA: Structure of type I-D Cascade bound to a dsDNA target

CRISPR-Cas systems are adaptive immune systems that protect prokaryotes from foreign nucleic acids, such as bacteriophages. Two of the most prevalent CRISPR-Cas systems include type I and type III. Interestingly, the type I-D interference proteins contain characteristic features of both type I and type III systems … CRISPR-Cas systems are…

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SARS-CoV-2 ORF8 protein binds to dendritic cells and induces a hyper-inflammatory cytokine storm

In a recent study posted to the bioRxiv* pre-print server, researchers examined how the interaction of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 8 (ORF8) protein with host dendritic cells (DCs) induced cytokine storm. ​​​​​​​Study: The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells…

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Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant

Subjects Normal breast and tumor samples were obtained with the written informed consent from donors and appropriate approval from local ethical committees, with the detailed information described in the respective original publications: normal tissue9, METABRIC14, TCGA35. Differential allelic expression analysis DNA and total RNA from 64 samples of normal breast…

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Annotating with CADD, gnomad, Clinvar & dbNSFP on UKB RAP – Feature Requests

dint May 9, 2022, 1:33pm #1 i’m just wondering if you can specify cadd, gnomad, clinvar and dbNSFP options when annotating with hail on dxjupyterlab_spark_cluster o the UKB RAP? From the hail website, the following command can be used on your matrix file to annotate with these features: db =…

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MAGEA12 shRNA Plasmid Human) – Gentaur.com

Catalog number MBS8252845 Supplier Price 647 EUR Size 0,15 mg Other size please contact us to order other different size Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the…

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Conflicted about job opportunities : comp_chem

Hello! I wanted to ask for some advice about how to manage and balance job opportunities when they come in. Not to humblebrag, but I’ve been offered a genuinely great postdoc opportunity where I’m certain I’d learn a lot with a potential to visit the lab in person soon. I…

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KEGG COMPOUND: C05172

Entry C05172                      Compound                                Name Selenophosphoric acid;Selenophosphate Formula H3PO3Se Exact mass 161.8985 Mol weight 160.9558 Structure Mol fileKCF fileDB search Reaction Pathway Enzyme Other DBs KCF data Show ATOM        5            1   P1b P    25.0600  -18.6200            2   O1c O    23.6600  -18.6200            3   O1c O    26.4600  -18.6200            4   O1c O    25.0600  -20.0200            5   Z   Se   25.0600  -17.2200BOND        4            1     1   2 1            2     1   3 1            3     1   4 2            4     1   5 1 Read more here: Source link

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Natera (NTRA) Presents New Data on Prospera and Renasight Tests

Get inside Wall Street with StreetInsider Premium. Claim your 1-week free trial here. Natera, Inc. (NASDAQ: NTRA) today announced that it has presented data on the clinical utility of the company’s Prospera™ and Renasight™ tests in 14 sessions at the American Transplant Congress (ATC) 2022 meeting. This expands on the…

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Supporting African BioGenome Project to build bioinformatics capacity

The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa AfricaBP and EMBL MoU. Credit: Karen Arnott/EMBL-EBI The African BioGenome Project (AfricaBP) is an African-led effort to sequence the genomes of all species indigenous to the…

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Researchers use nanotechnology to destroy and prevent relapse of solid tumor cancers

Generation and characterization of DCNV-rAd-Ag. a, Generation of DCNVs derived from adenovirus-infected mature dendritic cells. (1) The genes of tumor-specific antigen were genetically engineered into the adenovirus vector. (2) Recombinant adenovirus infected the immature DC2.4 cells to express the modified antigen on the cell surface and stimulate it. (3) Differentiation,…

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exact counts tables for limma voom guide

exact counts tables for limma voom guide 1 Is there a way to download the exact counts table associated with the limma voom guide? specifically for the tutorial in chapter 15 of the limma voom guide (GSE64099). I would like to to run through the commands and recreate the plots…

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VCV000038126.28 Observations – ClinVar – NCBI

1 SCV000301220.2 Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) Pathogenic reviewed by expert panel curation Breast-ovarian cancer, familial, susceptibility to, 2 (unknown ) germline Variant allele predicted to encode a truncated non-functional protein. 1 SCV000785901.2 Counsyl Pathogenic criteria provided,single submitter clinical testing Breast-ovarian cancer, familial, susceptibility to,…

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D.E. Analysis: Identifying Differentially-Expressed Genes between Experimental Groups

Username or Email Password Forgot your password? Sign In Cancel by RStudio Sign in Register D.E. Analysis: Identifying Differentially-Expressed Genes between Experimental Groups by HH Last updated about 17 hours ago Hide Comments (–) Share Hide Toolbars × Post on: Twitter Facebook Google+ Or copy & paste this link into…

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Dimorphic life cycle through transverse division in burrowing hard coral Deltocyathoides orientalis

Transverse division of Deltocyathoides orientalis In this study, we conducted a detailed morphological analysis of an undescribed species and D. orientalis. The results showed that the two species were different in terms of their mode of life (attached vs. free-living) and GCD size (Figs. 3 and 5, Supplementary Table S3)….

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Somatic point mutations are enriched in non-coding RNAs with possible regulatory function in breast cancer

Torre, L. A., Siegel, R. L., Ward, E. M. & Jemal, A. Global cancer incidence and mortality rates and trends—an update. Cancer Epidemiol. Prev. Biomark. 25, 16–27 (2016). Article  Google Scholar  Gerasimova, E. et al. Wavelet-based multifractal analysis of dynamic infrared thermograms to assist in early breast cancer diagnosis. Front….

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Table_8_RNA-Seq and 16S rRNA Analysis Revealed the Effect of Deltamethrin on Channel Catfish in the Early Stage of Acute Exposure.xls

Deltamethrin (Del) is a widely used pyrethroid insecticide and a dangerous material that has brought serious problems to the healthy breeding of aquatic animals. However, the toxicological mechanisms of Del on channel catfish remain unclear. In the present study, we exposed channel catfish to 0, 0.5, and 5 μg/L Del…

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can gff2 reference used in htseq-count?

Dear all We are recently working with E.coli plasmid and tried to summarize the gene counts from our RNA-Seq samples. The short reads were mapped to E.coli plasmid using tophat which generated bam files accordingly. However, we were unable to obtain a gff3 version of our target plasmid genome, the…

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Frontiers | Serum and Serum Exosomal CircRNAs hsa_circ_0001492, hsa_circ_0001439, and hsa_circ_0000896 as Diagnostic Biomarkers for Lung Adenocarcinoma

Introduction Lung cancer is associated with high morbidity and mortality and continues to be a major public health problem worldwide (1). Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer. While the 5-year survival rates of patients with lung cancer are still <15%, rates are closer to…

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python – Scikit optimize with objective function returning None

Can the expensive objective function that is being passed to scikit-optimize return None (NA/NaN/…) type? I would need to optimize simulation parameters and sometimes, the simulation can return a non-feasible result. I could theoretically return some artificially large number (1/ε), but that would probably break the scikit normality assumption. And…

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Cas12c provides antiviral immunity without the need to cut DNA

Graphical abstract. Credit: Molecular Cell (2022). DOI: 10.1016/j.molcel.2022.04.020 A trio of researchers at the University of California, Berkeley, has found that the protein Cas12c can provide antiviral immunity for bacteria without the need to cut DNA. In their paper published in the journal Molecular Cell, Carolyn Huang, Benjamin Adler and…

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Immatics and Editas Medicine Enter Strategic Research Collaboration and Licensing Agreement to Combine Gamma-Delta T Cell Adoptive Cell Therapies and Gene Editing for the Treatment of Cancer

Get instant alerts when news breaks on your stocks. Claim your 1-week free trial to StreetInsider Premium here. TUEBINGEN, Germany and HOUSTON and CAMBRIDGE, Mass., June 07, 2022 (GLOBE NEWSWIRE) — Immatics N.V. (Nasdaq: IMTX, “Immatics”), a clinical-stage biopharmaceutical company active in the discovery and development of T cell-redirecting cancer…

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Seven Bridges, Brazilian Researchers Applying Graph Analysis to Build Diverse Reference Genome

CHICAGO – The latest of Seven Bridges Genomics’ efforts to diversify reference genomes is its largest and perhaps most complex to date, an attempt to address the Brazilian population. The Charlestown, Massachusetts-based bioinformatics company recently joined with the University of São Paulo (USP), the Associação Genomas Brasil (Brazil Genome Association),…

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Phylogenomics and species delimitation of the economically important Black Basses (Micropterus)

Arlinghaus, R. et al. Governing the recreational dimension of global fisheries. Proc. Nat. Acad. Sci. USA 116, 5209–5213 (2019). CAS  PubMed  PubMed Central  Article  Google Scholar  Cowx, I. G. & Gerdeaux, D. The effects of fisheries management practises on freshwater ecosystems. Fish. Manag. Ecol. 11, 145–151 (2004). Article  Google Scholar …

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Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity

Visscher, P. M. et al. 10 years of GWAS discovery: biology, function, and translation. Am. J. Hum. Genet. 101, 5–22 (2017). CAS  PubMed  PubMed Central  Google Scholar  Buniello, A. et al. The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019. Nucleic Acids Res. 47,…

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Latest Data of InnoCare’s Robust Oncology Pipelines Presented at the 2022 ASCO Annual Meeting

BEIJING–(BUSINESS WIRE)–Latest data of InnoCare’s robust oncology pipeline were presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting. Poster Presentation 1: Phase I results of gunagratinib (ICP-192), a highly selective irreversible FGFR 1-4 inhibitor in patients with head and neck cancer (HNC) harboring FGF/FGFR gene aberrations Abstract…

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CISA Warned About Critical Vulnerabilities in Illumina’s DNA Sequencing Devices

The U.S. Cybersecurity and Infrastructure Security Agency (CISA) and Food and Drug Administration (FDA) have issued an advisory about critical security vulnerabilities in Illumina’s next-generation sequencing (NGS) software. Three of the flaws are rated 10 out of 10 for severity on the Common Vulnerability Scoring System (CVSS), with two others…

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Extract R1 and R2 from sam file generated by bowtie2

Extract R1 and R2 from sam file generated by bowtie2 1 Hi every one How to extract R1 and R2 from sam file generated by bowtie2 ? sam bowtie2 samtools bam • 137 views • link updated 14 hours ago by iraun &starf; 4.4k • written 15 hours ago by…

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YP3952 – YFull YTree Info

Q-YP3952 – YFull YTree Info Sample ID Country / Language Info Ref File Testing company Statistics Status YF073154 Russia (Chechenskaya Respublika) / Chechen Q-YP3952* —— Hg38 .BAM FTDNA (Y700) 33X, 18.2 Mbp, 151 bp YF092378 Russia (Chechenskaya Respublika) / Chechen Q-BZ87 —— Hg38 .BAM FTDNA (Y700) 55X, 18.5 Mbp, 151…

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AM744997 | EVAg

Can’t find a specific product ? Simply ask us !   One of the most interesting features of EVAg’s catalogue is its flexibility, please do not hesitate to contact us by using  our contact form. We can add to the catalogue tailor-made products on demand, as well as access to…

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Origin26 Next-Generation DNA-Based Healthcare Coming Soon with World’s First DeSci Genomic Project

Origin26 is a trailblazing blockchain application for predictive healthcare using genetic data. People across the world will be able to own, manage and share their DNA tests and genome data for scientific research and predictive healthcare. Origin26 A newly emerging Web3 trend, Decentralized Science (DeSci), much like the hugely popular…

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linux merge multiple files in picard

Why not use samtools? for folder in my_bam_folders/*; do samtools merge $folder.bam $folder/*.bam done In general, samtools merge can merge all the bam files in a given directory like this: samtools merge merged.bam *.bam EDIT: If samtools isn’t an option and you have to use Picard, what about something like…

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main-i386-default][science/cp2k] Failed for cp2k-9.1.0 in configure

You are receiving this mail as a port that you maintain is failing to build on the FreeBSD package build server. Please investigate the failure and submit a PR to fix build. Maintainer: y…@freebsd.org Log URL: beefy17.nyi.freebsd.org/data/main-i386-default/p429f3de9bdcd_s2573e6ced9/logs/cp2k-9.1.0.log Build URL: beefy17.nyi.freebsd.org/build.html?mastername=main-i386-default&build=p429f3de9bdcd_s2573e6ced9 Log: =>> Building science/cp2k build started at Sat Jun 4…

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python3.7 biopython, how to learn python3 and still use biopython

Firstly, check out this page: biopython.org/wiki/Download You don’t have to worry about biopython being bound to a specific version of python – you can use it with either v2.7 or v3.4/v3.5/v3.6. You can also have multiple version installed on your system but I recommend you to focus on digging deeper…

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man Bio::SeqIO::fasta (3): fasta sequence input/output stream

Bio::SeqIO::fasta(3) fasta sequence input/output stream SYNOPSIS Do not use this module directly. Use it via the Bio::SeqIO class. DESCRIPTION This object can transform Bio::Seq objects to and from fasta flat file databases. FEEDBACK Mailing Lists User feedback is an integral part of the evolution of this and other Bioperl modules….

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Bioconductor – sSNAPPY (development version)

DOI: 10.18129/B9.bioc.sSNAPPY     This is the development version of sSNAPPY; for the stable release version, see sSNAPPY. Single Sample directioNAl Pathway Perturbation analYsis Bioconductor version: Development (3.16) A single sample pathway pertrubation testing methods for RNA-seq data. The method propagate changes in gene expression down gene-set topologies to compute…

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fatal error in autodock

fatal error in autodock 1 Hlo everyone i am facing fatal error when i am running autoduck4. please suggest me how i can fix this error C:/Users/Public/Autodocking/autodock4: FATAL ERROR: C:/Users/Public/Autodocking/autodock4: ERROR: All ATOM and HETATM records must be given before any nested BRANCHes; see line 25 in PDBQT file “ligand.pdbqt”….

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python 3.x – No torchdyn library found in kaggle

I am trying to install torchdyn in my kaggle enviroment. However, when I try to install by following: pip install torchdyn I get the following error: ERROR: Ignored the following versions that require a different python version: 0.3.0 Requires-Python >=3.8,<4.0 ERROR: Could not find a version that satisfies the requirement…

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UniProtKB – Q27974

UniProtKB – Q27974 <p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.</p> <p><a href=”www.uniprot.org/manual/evidences”>More…</a></p>&#13; Skip Header You are using a version of browser that may not display all the features…

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Running DESeq2 from rpy2 – Askdevz

If you open R and type: you will see that the assay function is not actually coming from DESeq2, but from its dependency which is called SummarizedExperiment: > assay standardGeneric for “assay” defined from package “SummarizedExperiment” function (x, i, withDimnames = TRUE, …) standardGeneric(“assay”) <bytecode: 0x5586a354db90> <environment: 0x5586a3535e20> Methods may…

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Jobs on jobactive hiring Postdoctoral Bioinformatician in Single Cell and Spatial Omics Data Analysis in Adelaide, South Australia, Australia

Full-Time, 2 Year Contract Salary range $95,000 – $110,000 At the South Australian Health and Medical Research Institute (SAHMRI), we are committed to achieving innovative, ground-breaking health and medical research that fundamentally improves the quality of life for all people. The South Australian Genomics Centre (SAGC) is a multi-institutional, national…

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Bioinformatics Specialist I — Cancer Computational Biology —- Cancer Center in Boston, MA for MGH Institute of Health Professions

Details Posted: 05-Jun-22 Location: Boston, Massachusetts Salary: Unpaid Internal Number: 3190190-3499_1654275737 URLs: www.massgeneral.org/cancer-center/clinical-trials-and-research/center-for-cancer-research/investigators/rheinbay-lab www.massgeneral.org/cancer-center/clinical-trials-and-research/center-for-cancer-research/investigators/lawrence-lab Unique opportunity to join an interdisciplinary team bridging the Harvard Medical School, the Massachusetts General Hospital, and the Broad Institute of Harvard and MIT. The Rheinbay Lab and Lawrence Lab at the Massachusetts General Hospital Cancer…

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New gene-edited tomatoes boost vitamin D levels

An international team of scientists primarily based out of the John Innes Centre in the United Kingdom has used gene-editing to create a vitamin D-enriched tomato. Using CRISPR-Cas9, they switched off an enzyme in tomatoes that ordinarily prevents the molecular forerunner of vitamin D3 (called 7-dehydrocholesterol, or 7-DHC) from accumulating…

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Job availability: Outreach & Public Engagement Officer

The EMBL is looking to recruit an enthusiastic, highly motivated Outreach & Public Engagement Officer to join the European Learning Laboratory for Life Sciences (ELLS) Team in Heidelberg, Germany. About the role You will develop and deliver a programme of engagement activities that supports EMBL’s scientific programme, with a special…

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how to predict gene expression from genotype file using already developed elastic net model

how to predict gene expression from genotype file using already developed elastic net model 0 Hello everyone, I want to predict gene expression from genotype file and already developed elastic net model. My model file look like this: GENE RSID1 RSID2 VALUE ENSG00000107937.18 rs7475652 rs7475652 0.531316876443232 ENSG00000107937.18 rs7475652 rs7918643 -0.1434806647803035…

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iPhone users can now add vaccine records to Apple Health, checkout steps

iPhone users can keep their COVID-19 vaccination card in Apple Wallet and use it to confirm that they have been fully vaccinated. According to Mashable, customers and visitors must also demonstrate that they are up to date on their doses, even if these criteria only apply to personnel in particular…

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Genome hg19**not found in homer config

I want to use the Homer to do annotation. After I input “annotatePeaks.pl 31512_TH0_D0.bed hg19 > 31512_TH0_D0.ann.txt” , it shows “!!!!Genome hg19 not found in /home/jenny/NGStools/homer/.//config.txt” I used the command “perl /home/jenny/NGStools/homer/configureHomer.pl -install hg19” to install it, and I am sure I installed the hg19 for the homer Then input…

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How do I add a legend? I want to add legend to ggplot. please help me

How do I add a legend? I want to add legend to ggplot. please help me ka<-read.table(file = “K”,encoding= “UTF-8”,header = T) library(ggplot2) options(scipen=100) ka <- data.frame(aa = 2017:2020, bb = c(55550000,66660000,77770000,88880000), cc = c(12345,56789,23456,56756)) ggplot(ka, aes(aa)) + geom_col(aes(x=aa, y = bb/100), fill = “#F5513B”) + geom_line(aes(x=aa, y = cc))…

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Jupyter WebIO in binder – JupyterHub

I just learned how to run julia notebooks in binder. Now I want to use the PlotlyJS package in julia. Usually, when I need a package in julia on binder, I install it locally in a conda environment first and then copy Project.toml and Manifest.toml to my repository to start…

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BBMap 38.90-GCC-10.2.0 (for BlueBEAR, BEARCloud VMs, and CaStLeS VMs)

BBMap 38.90-GCC-10.2.0 Unsupported: Use of this version of BBMap is not supported. More information on our Applications Support and Retention Policy. BBMap short read aligner, and other bioinformatic tools. Accessing BBMap 38.90-GCC-10.2.0 To load the module for BBMap 38.90-GCC-10.2.0 please use this command on the BEAR systems (BlueBEAR, BEARCloud VMs,…

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PyMC3 Normal with variance per column

One can pass an argument for the shape parameter to achieve this. To demonstrate this, let’s make some fake data to pass as observed, where we use fixed values for epsilon that we can compare against the inferred ones. import numpy as np import pymc3 as pm import arviz as…

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NuProbe Closes $50M Funding – AI EXPRESS

NuProbe Global, a Houston, TX- and Shanghai, China-based genomics and molecular diagnostics firm, raised $50M in funding. The spherical was co-led by AstraZeneca-CICC Fund, CR-CP Life Science Fund, and Panlin Capital.  Current buyers Sequoia Capital China, Biotrack Capital, and Yonghua Capital and new buyers Pappas Capital, Haoreng Capital, and Deguan…

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PYTHON: Convert each CSV Row into XML File sepperate

You are overwriting the same file everytime in your loop. You need to change the file-name as well: pFile = ‘test.csv’ oFile = ‘test’ #add xml later if os.path.isfile(pFile) and pFile.endswith(ext): with open(pFile, ‘r’) as pData: reader = csv.reader(pData) pData = {} for i, row in enumerate(reader, 1): #count each…

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A Standardized, Specification-Driven API Lifecycle

Transcript Lane: I’d like to share with you a high level view of why API specifications matter. How OpenAPI, AsyncAPI, JSON Schema and others are helping us standardize and deliver API lifecycle in a way that the machines understand. Also, allows us humans to better communicate, collaborate, and move forward…

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