Tag: apex

ALDH2 mitigates LPS-induced cardiac dysfunction, inflammation, and apoptosis through the cGAS/STING pathway | Molecular Medicine

Reagents and antibodies The details of the drugs and related reagents used in this study are presented in Additional file 1: Table S1. Animals A total of 48 male C57BL/6 mice were purchased from Byrness Weil Biotech Ltd. (License number: SCXK (Xiang) 2019-0004). The mice were of SPF-grade and had…

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Apex Systems hiring Scientist II, Bioinformatics, Machine Learning in Watertown, MA

Job#: 1367574Job Description:Scientist II, Bioinformatics, Machine Learning (1367574) Location: Watertown, MA (Onsite) Science: Gene Editing Therapeutic Area: Genetic Diseases Job Overview: Our client is seeking a talented Bioinformatics Data Scientist to join their growing team and play a crucial role in the expansion of their platform. In this role, you…

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Electric eels have the ability to mutate other creatures just by shocking them!

In a fascinating turn of nature, Amazon‘s electric eels possess the remarkable ability to produce up to 860 volts of electricity—more than sufficient to power typical household devices. However, their extraordinary power serves purposes beyond merely stunning prey.Recent research reveals that these eels, resembling catfish, can influence the genetic composition…

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Electric Eels Can Alter Genetic Makeup of Other Organisms By Shocking Them: Study

Researchers discovered that electric eels, the biggest power-making creature on Earth, can release enough electricity to genetically modify small fish larvae. (Shintaro Sakaki) Ever met someone with a personality so electrifying that they can alter the very DNA of those around them? In a remarkable twist of nature, the Amazon’s…

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Distributed Model Training on PyTorch 2.0 GPU

Mastering GPT 4 Training: Distributed Model Training on PyTorch 2.0 GPU Introduction Building a Business Using Large Language Models Understanding Distributed Training What is Distributed Training? How Does Distributed Training Work? Concepts and Libraries Associated with Distributed Training PyTorch: An Overview What is PyTorch? Features of PyTorch Automatic Differentiation and…

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Vertex App Software Review – Vertex OTO By Venkata Ramana | Tomreview99

Vertex App Software ReviewPhoto byTom YouTube is the world’s largest video platform and a lucrative source of income for many people. It’s like a gold mine waiting to be discovered by you. How big is this gold mine? It’s worth over $200 billion and growing every year. You can see…

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Murine Orchiectomy and Ovariectomy to Reduce Sex Hormone Production

The overall goal of this procedure is to demonstrate the surgical removal of murine testes and ovaries in a fast, safe, and effective manner. Murine orchiectomy is performed by a ventral midline incision into the scrotal sac, where the testes are isolated and removed, followed by closure of the skin…

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Electroporation Transformation of Barley | SpringerLink

Ahloowalia BS (1987) Plant regeneration from embryo-callus culture in barley. Euphytica 36: 659–665 CrossRef  Google Scholar  Ahokas H (1989) Transfection of germinating barley seed electrophoretically with exogenous DNA. Theor Appl Genet 77: 469–472 CrossRef  CAS  Google Scholar  Barro F, Cannell ME, Lazzeri PA, Barcelo P (1998) The influence of auxins…

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Could Jurassic Park happen?

Could Jurassic Park happen? IntroductionIn a world captivated by the wonders of science and the mysteries of the past, the question of whether Jurassic Park could become a reality has sparked both excitement and concern. Inspired by Michael Crichton’s novel and subsequent film franchise, the concept of resurrecting dinosaurs from…

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Salesforce Data Cloud and Vertex AI

This has been the year of artificial intelligence in the Salesforce ecosystem. Although 2023 is coming to an end, the announcements just keep on coming. Salesforce has recently announced that Google Vertex AI models are now generally available in Einstein Studio. In this post, I’ll delve into what this actually…

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Fonsecaea monophora causing cerebral phaeohyphomycosis

Introduction Phaeohyphomycosis (PHM) is a group of superficial and deep mycoses, including central nervous system (CNS) infections, pulmonary infections, cutaneous and subcutaneous infections, associated with high mortality and caused by dematiaceous fungi that have brown-pigmented cell walls due to the formation of melanin.1,2 Previously, fungal brain infections generally occurred in…

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Bring Your Google Vertex AI Models to Data Cloud

Model Builder, part of Einstein Copilot Studio, is a user-friendly platform that enables you to create and operationalize AI models in Salesforce. Model Builder is capable of deeply integrating with external AI platforms, such as Google Cloud Vertex AI and Amazon SageMaker, so you can build, train, and deploy custom…

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Bioconductor – Bioconductor 3.18 Released

Home Bioconductor 3.18 Released October 25, 2023 Bioconductors: We are pleased to announce Bioconductor 3.18, consisting of 2266 software packages, 429 experiment data packages, 920 annotation packages, 30 workflows and 4 books. There are 69 new software packages, 10 new data experiment packages, 8 new annotation packages, no new workflows,…

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A Bioconductor workflow for processing, evaluating,…

Introduction Proteins are responsible for carrying out a multitude of biological tasks, implementing cellular functionality and determining phenotype. Mass spectrometry (MS)-based expression proteomics allows protein abundance to be quantified and compared between samples. In turn, differential protein abundance can be used to explore how biological systems respond to a perturbation….

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Ancient Sea Monster Remains Reveal Oldest Mega-Predatory Pliosaur

The fossils of a 170-million-year-old ancient marine reptile from the Age of Dinosaurs have been identified as the oldest-known mega-predatory pliosaur—a group of ocean-dwelling reptiles closely related to the famous long-necked plesiosaurs. The findings are rare and add new knowledge to the evolution of plesiosaurs. The study has been published…

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Bringing Animals Back from Extinction

“Your scientists were so preoccupied with whether or not they could that they didn’t stop to think if they should,” Jeff Goldblum’s character Ian Malcolm tells an indignant park owner John Hammond played by Richard Attenborough in the 1993 classic film Jurrasic Park. Ben Lamm is not quite John Hammond…

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7 cloud market trends and how they will impact IT

And for CIOs looking to make the most of gen AI capabilities built into the cloud offerings they depend on, initial explanations as to how pricing will work have been rather opaque. Cloud price creep — with leaps thanks to AI IBM caused quite a stir when it announced price…

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Wolf microbiome holds potential dog probiotic

Dogs don’t need to eat like wolves, but pet dogs may benefit from digesting like their undomesticated cousins, providing another reason for protecting wolf populations. The gut microbiome of wild wolves may contain species that could help resolve pet dogs’ digestive problems. In the gastrointestinal tract of a grey wolf…

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Genomic insights into Bacillus subtilis MBB3B9 mediated aluminium stress mitigation for enhanced rice growth

Bian, M. et al. Development of gene-specific markers for acid soil/aluminium tolerance in barley (Hordeum vulgare L.). Mol. Breed. 32, 155–164 (2013). Article  CAS  Google Scholar  Kochian, L. V., Piñeros, M. A., Liu, J. & Magalhaes, J. V. Plant adaptation to acid soils: The molecular basis for crop aluminum resistance….

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The University of British Columbia hiring Bioinformatics Programmer/Specialist in Vancouver, British Columbia, Canada

Staff – Non UnionJob CategoryM&P – AAPSJob ProfileAAPS Salaried – Information Systems and Technology, Level BJob TitleBioinformatics Programmer/SpecialistDepartmentWasserman Laboratory | Centre for Molecular Medicine and Therapeutics | Faculty of MedicineCompensation Range$5,468.83 – $7,878.17 CAD MonthlyThe Compensation Range is the span between the minimum and maximum base salary for a position….

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Google Foundation for AI: Streamline Your Workflows with Vertex AI and Harness Three Distinct PaLM 2 Modes. Join Us for an AI Journey!” | Saraswwathy (Sara) Swaminathan posted on the topic

Struggling to turn skills into cash? Want to live your dream day, every day? I’ve cracked the code, and I’m handing you the manual: ? Here’s your reality check: • High-paying clients are everywhere. • Nail your niche and master outreach. • Testimonials are your golden tickets. Crank volume, build…

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Groundbreaking Research Extracts RNA from Extinct Tasmanian Tiger

Once upon a time, the Australian continent and its adjoining islands were home to an apex predator, the Tasmanian tiger. Also known as the thylacine, this striped, dog-sized carnivorous marsupial subsisted primarily on kangaroos and other similar prey. Sadly, due to human activities, the species is no longer present in…

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Stem Cell Hair Transplant Treatment Market Rise in Share, Size 2023 Trends with Key Players

PRESS RELEASE Published September 22, 2023 The report provides a comprehensive analysis of The Stem Cell Hair Transplant Treatment Market, covering various aspects such as market size, market status, market trends, and forecast. The report also highlights the key market drivers, growth opportunities, and competitive landscape. The market size and…

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RNA for the first time recovered from an extinct species

A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note…

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In a first, RNA is recovered from extinct Tasmanian tiger | WKZO | Everything Kalamazoo

By Will Dunham (Reuters) – The Tasmanian tiger, a dog-sized striped carnivorous marsupial also called the thylacine, once roamed the Australian continent and adjacent islands, an apex predator that hunted kangaroos and other prey. Because of humans, the species is now extinct. But that does not mean scientists have stopped…

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In a first, RNA is recovered from extinct Tasmanian tiger

Three views of the desiccated remains of an extinct marsupial mammal called the Tasmanian tiger, or the thylacine, from a collection at the Swedish Museum of Natural History in Stockholm are seen in this undated handout image. Emilio Marmol Sanchez/Handout via REUTERS Acquire Licensing Rights Sept 19 (Reuters) – The…

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Exploring associations between the teat apex metagenome and Staphylococcus aureus intramammary infection risk in primiparous cows under organic directives

Abstract The primary objective of this study was to identify associations between teat apex microbiome and Staphylococcus aureus intramammary infection (IMI) risk in primiparous cows during the first 5 weeks after calving. We performed a case-control study using shotgun metagenomics of the teat apex and culture-based milk data collected longitudinally…

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The future of companies is being shaped by data and artificial intelligence, as demonstrated by Salesforce Dreamforce 2023

Although it was announced a few days before Dreamforce 2023, Salesforce and news outlets are preparing for your event. The primary updates are the Einstein Platform 1, which includes several enhancements to Salesforce Data Cloud and Einstein AI, as well as the new AI technology, Einstein, which includes both Copilot…

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Salesforce Launches Einstein 1, Einstein Copilot, and Expanded Google Partnership at Dreamforce

Salesforce today at its massive Dreamforce conference in San Francisco introduced the next generation o Einstein, its artificial intelligence technology, with the Einstein 1 platform, Einstein Copilot, Einstein Copilot Studio, Einstein Trust Layer, and an expanded partnership with Google Cloud. The Einstein 1 Platform features major advancements for Salesforce Data…

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Salesforce Launches Next Generation of Einstein, Bringing a Conversational AI Assistant to Every CRM Application and Customer Experience

SAN FRANCISCO–(BUSINESS WIRE)–Salesforce (NYSE: CRM) today introduced the next generation of Einstein, its AI technology. Einstein now includes: “With Einstein Copilot and Data Cloud we’re making it easy to create powerful AI assistants and infuse trusted AI into the flow of work across every job, business, and industry. In this…

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Salesforce Expands Einstein AI and Data Cloud Platform

Image: Sundry Photography/Adobe Stock Salesforce announced a rebrand of its Einstein 1 Data Cloud and new capabilities for the Einstein generative AI assistant for CRM at the Dreamforce conference held in San Francisco on Tuesday, Sept. 12. Salesforce’s Einstein 1 Data Cloud metadata framework will be integrated within the Einstein…

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Apex Systems hiring Data Scientist, Bioinformatics in Watertown, Massachusetts, United States

Job#: 1367574Job Description:Data Scientist, Bioinformatics 1367574Location: Watertown, MA (Onsite)Science: Gene EditingTherapeutic Area: Genetic DiseasesJob Overview: Our client is seeking a talented Bioinformatics Data Scientist to join their growing team and play a crucial role in the expansion of their platform. In this role, you will be responsible for developing innovative…

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Data Scientist, Bioinformatics | Apex Systems

Job#: 1367574 Job Description: Data Scientist, Bioinformatics 1367574 Location: Watertown, MA (Onsite) Science: Gene Editing Therapeutic Area: Genetic Diseases Job Overview:   Our client is seeking a talented Bioinformatics Data Scientist to join their growing team and play a crucial role in the expansion of their platform. In this role, you will be responsible…

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Exosomal circEZH2_005, an intestinal injury biomarker, alleviates intestinal ischemia/reperfusion injury by mediating Gprc5a signaling

Human plasma collection Fifty patients who were assigned for CPB surgery between May 2021 and February 2022 at the Department of Cardiac Surgery, Southern Medical University Nanfang Hospital (Guangzhou, China) were recruited given their increased risk of intestinal I/R injury. In patients undergoing cardiac surgery, CPB is potentially responsible for…

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A G1528C Hadha knock-in mouse model recapitulates aspects of human clinical phenotypes for long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency

All animal procedures were reviewed and approved by the OHSU IACUC (eIACUC #B11243). All experiments were performed in accordance with AAALAC and ARRIVE guidelines. Age, sex, and N of the mice for each experiment can be found in Supplementary Data 1. Mouse creation Mice were created through Cyagen Biosciences (Santa Clara,…

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Fairseq: A Sequence Modeling Toolkit Written in PyTorch

Fairseq is a sequence modeling toolkit written in PyTorch feature: Multi-GPU training on one machine or multiple machines (data and model parallelism) Generates quickly on CPU and GPU and implements multiple search algorithms: Beam Search Diversified Beam Search (Vijayakumar et al., 2016 ) Sampling (unconstrained, top-k and top-p/nucleus) Lexically Constrained…

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IJMS | Free Full-Text | CRISPR/Cas9-Mediated HY5 Gene Editing Reduces Growth Inhibition in Chinese Cabbage (Brassica rapa) under ER Stress

1. Introduction Crops such as rapeseed, along with vegetables like cabbage and Chinese cabbage, all of which belong to the Brassica genus, are widely cultivated across the world. Chinese cabbage, in particular, holds significant commercial importance as a vegetable extensively consumed in Asian countries [1,2,3]. Chinese cabbage thrives well in…

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Image_1_Pseudotemporal ordering of spatial lymphoid tissue microenvironment profiles trails Unclassified DLBCL at the periphery of the follicle.pdf

We have established a pseudotemporal ordering for the transcriptional signatures of distinct microregions within reactive lymphoid tissues, namely germinal center dark zones (DZ), germinal center light zones (LZ), and peri-follicular areas (Peri). By utilizing this pseudotime trajectory derived from the functional microenvironments of DZ, LZ, and Peri, we have ordered…

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Stem Cell Services Market to Receive Overwhelming Hike in Revenues by 2030 With key Players Paragon Bioservices, APEX Biologix, VcanBio, Cryo-cell

PRESS RELEASE Published August 18, 2023 Stem Cell Services Market report available at Infinity Business Insights. This report contains detailed information on clientele, applications and contact information. This report will help the viewer in Better Decision Making. The size of the worldwide Stem Cell Services Market, which was estimated to…

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Stem Cell Services Market Regenerative Medicine Growth 2030

PRESS RELEASE Published August 18, 2023 Stem Cell Services Market report available at Infinity Business Insights. This report contains detailed information on clientele, applications and contact information. This report will help the viewer in Better Decision Making. The size of the worldwide Stem Cell Services Market, which was estimated to…

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Risk Intelligence Analyst – Apex Systems

Job#: 1366837 Job Description: EEO Employer Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic…

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Spatial transcriptomics: recent developments and insights in respiratory research | Military Medical Research

Zepp JA, Morrisey EE. Cellular crosstalk in the development and regeneration of the respiratory system. Nat Rev Mol Cell Biol. 2019;20(9):551–66. Article  CAS  PubMed  PubMed Central  Google Scholar  Kiley JP. Advancing respiratory research. Chest. 2011;140(2):497–501. Article  PubMed  PubMed Central  Google Scholar  Goldstraw P, Ball D, Jett JR, Le Chevalier T,…

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Artificial intelligence innovator John Jumper to deliver Aug. 30 Apex Lecture | VUMC Reporter

John Jumper by Bill Snyder John Jumper, who led the development of AlphaFold, an artificial intelligence (AI) system that can rapidly and accurately predict the three-dimensional structure of proteins, will give the next Apex Lecture on Wednesday, Aug. 30. Open to the Vanderbilt University and Vanderbilt University Medical Center community,…

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Apex Systems hiring Senior/Principal Scientist, Bioinformatics in Waltham, Massachusetts, United States

Job#: 1364647Job Description:Principal Scientist, Bioinformatics 1364647Location: Waltham, MA (Remote)Science: Small Molecule TherapeuticsTherapeutic Area: OncologyJob Overview: This position will be responsible for advancing RNA-targeting drug discovery with computational tools. The primary focus of the role include developing algorithms, software packages, and analysis pipelines for various omics data.Qualifications: Ph.D. in related field…

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John Jumper, developer of AlphaFold, to present an Apex Lecture on August 30 – School of Medicine Basic Sciences School of Medicine Basic Sciences

Posted by dostersm on Tuesday, August 8, 2023 in Discoveries, News & Discoveries . John Jumper, Ph.D. To highlight major inflection points in research, the Vanderbilt School of Medicine Basic Sciences launched the Apex Lecture Series earlier this year, which allows the Basic Sciences community to engage with researchers from around…

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Cogent Biosciences Reports Recent Business Highlights and Second Quarter 2023 Financial Results

Initial clinical results from Phase 2 SUMMIT trial in NonAdvSM along with updated data from Phase 2 APEX trial in AdvSM on track for 2H 2023 Enrollment for Phase 3 PEAK trial in GIST continues on track Selective FGFR2 inhibitor nominated as first Cogent-discovered clinical candidate; additional preclinical data planned…

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Salesforce Introduces Einstein Studio to Streamline AI Model Development

Salesforce has announced the launch of Einstein Studio, a new offering that allows enterprises to connect and train their own AI models on proprietary data within the Salesforce platform. This “bring-your-own-model” experience aims to streamline the AI project lifecycle, enabling data science and engineering teams to manage and deploy models…

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Salesforce launches Einstein Studio for training AI models with Data Cloud

Head over to our on-demand library to view sessions from VB Transform 2023. Register Here Salesforce is moving the needle on AI. The Marc Benioff-led CRM leader today announced the launch of Einstein Studio, a new “bring-your-own-model” experience that allows enterprises to connect and train their own AI models on…

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Salesforce Launches BYOM to Make It Easy for Businesses to Use Proprietary Data to Build and Deploy AI Models

Salesforce today announced the general availability of Einstein Studio, a new, easy-to-use “bring your own model” (BYOM) solution that enables companies to use their custom AI models to power any sales, service, marketing, commerce, and IT application within Salesforce, helping them get more from their AI and data investments.  Einstein…

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The master growth regulator DELLA binding to histone H2A is essential for DELLA-mediated global transcription regulation

Peng, J. et al. ‘Green revolution’ genes encode mutant gibberellin response modulators. Nature 400, 256–261 (1999). Article  CAS  PubMed  Google Scholar  Eshed, Y. & Lippman, Z. B. Revolutions in agriculture chart a course for targeted breeding of old and new crops. Science 366, eaax0025 (2019). Article  CAS  PubMed  Google Scholar …

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PyTorch Release 23.07 – NVIDIA Docs

The NVIDIA container image for PyTorch, release 23.07 is available on NGC. Contents of the PyTorch container This container image contains the complete source of the version of PyTorch in /opt/pytorch. It is prebuilt and installed in the default Python environment (/usr/local/lib/python3.10/dist-packages/torch) in the container image. The container also includes…

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Cloud and application platform providers invest in GenAI integrations

Application platform providers have been heavily investing in generative AI (GenAI) integrations to gain an edge in the cloud wars. This allows them to provide greater access to advanced innovations in the cloud. Enterprises are also considering the impact of GenAI technologies, ecosystems, and security/ethics/regulatory issues on their businesses. Automation…

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Automation platforms are latest to seek competitive edge via GenAI

Cloud and application platform providers remain at the forefront of prominent GenAI announcements. Credit: HelloRF Zcool via Shutterstock. In recent months, application platform providers have been heavily investing in generative AI (GenAI) integrations, looking for an edge in the cloud wars by granting greater access to advanced innovations typically reserved…

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Human Heart Cell Atlas Highlights Cardiac Functions, Drug Targets

NEW YORK – An international team of researchers has put together an atlas of the human heart that spells out transcriptomic and chromatin accessibility features in individual, spatially mapped cells across eight distinct areas. “In this study, we charted eight regions of the human heart and provided the most detailed…

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Kaggle is a practical study of Big Data. What is this platform and how does it work

Skip to content Prog.World Prog.World Toggle Menu Share this: Facebook Reddit Pinterest Telegram WhatsApp Skype Post navigation Previous Previous Parsing a small application with jokes NextContinue How ChatGPT User Data Leaks Are Framing Users Similar Posts Online meetup of the MSK VUE.JS developer community Python – Dict You can’t just…

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Trematode and Monogenean rRNA ITS2 Secondary Structures Support a Four-Domain Model

The secondary structure of rRNA internal transcribed spacer 2 is important in the process of ribosomal biogenesis. Trematode ITS sequences are poorly conserved and difficult to align for phylogenetic comparisons above a family level. If a conserved secondary structure can be identified, it can be used to guide primary sequence…

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Compass Pathways: Explorers Of The Neurological Frontier (NASDAQ:CMPS)

AlexSava Sometimes deviation is merely a stage in progression. COMPASS Pathways plc (NASDAQ:CMPS) research exemplifies that notion. CMPS is a mental healthcare company that specializes in psilocybin therapy. It’s produced the two largest psilocybin trials ever recorded and has made remarkable discoveries regarding the effects of psilocybin. CMPS is presently…

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NIH Study Demonstrates Nanopore Sequencing for Population-Scale Genomics

NEW YORK – Researchers at the National Institutes of Health and their collaborators have shown that nanopore long-read sequencing can be used on a population scale to help understand the genetics of Alzheimer’s disease and related dementias. In a preprint posted on BioRxiv in April, they outlined wet-lab and computational…

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Cochlea cell atlas built from single-cell sequencing discovers new cell types, uncovers hidden molecular features

Transcriptomic characterization of cochlear cell types. (A) Experimental design of the study. (B, Left) T-SNE plots depicting the scRNAseq (P8-P12-P20) and the snRNAseq (P8) datasets. (B, Right) Diagram of the cochlea depicting the main cell-type ensembles characterized. (C) Bubble plot analysis of the most differentially expressed gene for each cochlear…

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EQTL news, real time EQTL stock news, Equitech Intl news today

Securities trading is offered to self-directed customers by Webull Financial LLC, a broker dealer registered with the Securities and Exchange Commission (SEC). Webull Financial LLC is a member of the Financial Industry Regulatory Authority (FINRA), Securities Investor Protection Corporation (SIPC), The New York Stock Exchange (NYSE), NASDAQ and Cboe EDGX…

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The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer

Cell lines and culture conditions All media and supplements were purchased from Gibco unless otherwise stated. OC cell line SKOV3, OVCA429, CH1 and NSCLC cell line H1299 and A549 were maintained using Dulbecco’s Modified Eagle Medium (DMEM) media supplemented with 10% (v/v) foetal bovine serum (FBS). OC cell lines HeyA8,…

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Salesforce AI Cloud, enterprise artificial intelligence

70 Salesforce has announced AI Cloud, to enhance customer experience and productivity through generative artificial intelligence aimed at the enterprise world. AI Cloud is a suite of capabilities optimized to deliver reliable, accessible, real-time generative experiences across applications and workflows. AI Cloud’s new Einstein GPT Trust Layer addresses the concerns…

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how to use bert embeddings pytorch

At every step of decoding, the decoder is given an input token and Plotting is done with matplotlib, using the array of loss values How to handle multi-collinearity when all the variables are highly correlated? of examples, time so far, estimated time) and average loss. For policies applicable to the…

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Ec Cancellation: Seiaa To Seek Legal Advice On Filing Appeal | Thiruvananthapuram News

Thiruvananthapuram: The state environment impact assessment authority (SEIAA) has decided to seek legal advice regarding the provision of appeal against the National Green Tribunal (NGT) order which cancelled the environmental clearance (EC) for the expansion of the mixed land use (master plan) project by Dragonstone Realty Private Limited at Technopark…

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Influence of ecological traits on spatio-temporal dynamics of an elasmobranch community in a heavily exploited basin

Stevens, J. The effects of fishing on sharks, rays, and chimaeras (chondrichthyans), and the implications for marine ecosystems. ICES J. Mar. Sci. 57, 476–494. doi.org/10.1006/jmsc.2000.0724 (2000). Article  Google Scholar  Ferretti, F., Worm, B., Britten, G. L., Heithaus, M. R. & Lotze, H. K. Patterns and ecosystem consequences of shark declines…

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Salesforce AI Cloud Seeks To Combat ‘Trust Gap,’ Hallucinations

Cloud News Wade Tyler Millward June 13, 2023, 09:55 AM EDT ‘When we talk about privacy, when we talk about hallucinations, when we talk about data control, when we talk about bias, when we talk about toxicity … these are actual technical explanations of things that…

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Salesforce launches AI Cloud to bring models to the enterprise

Salesforce is launching a new suite of products aimed at bolstering its position in the ultra-competitive AI space. Called AI Cloud, the suite, which includes tools designed to deliver “enterprise ready” AI, is Salesforce’s latest cross-disciplinary attempt to augment its product portfolio with AI capabilities. In many ways, it’s a…

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Aridis Pharmaceuticals Announces First Quarter 2023 Financial Results and Business Update

LOS GATOS, Calif., June 08, 2023 (GLOBE NEWSWIRE) — Aridis Pharmaceuticals, Inc. (Nasdaq: ARDS), a biopharmaceutical company focused on the discovery and development of novel anti-infective therapies for treating life-threatening infections, today reported financial and corporate results for its first quarter ended March 31, 2023. First Quarter & Subsequent Highlights Met…

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Facultative Parthenogenesis Recorded in Crocodilians for First Time Ever

Using whole-genome sequencing and bioinformatic analysis, scientists provide the first evidence of facultative parthenogenesis in a crocodilian — the American crocodile (Crocodylus acutus), a large and wide-ranging apex predator that occurs from Florida to Colombia, Venezuela and Peru. An adult American crocodile (Crocodylus acutus) at La Manzanilla, Jalisco, Mexico. Image…

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Bioinformatics Analyst II – RNA Biology job with Baylor College of Medicine

Summary Dr. Fazal is seeking a Bioinformatics Analyst II to develop and apply genomic analysis tools to identify cis- and trans- factors associated with RNA localization. The Fazal lab is a young laboratory focusing on systematically interrogating the subcellular transcriptomes of mammalian cells and characterizing the scope, regulation, and function…

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Fused mixed precision updates with PyTorch amp – mixed-precision

cbcase (Carl C) June 6, 2023, 6:22pm 1 I am trying to get up to speed on the latest support for mixed precision in PyTorch. One thing that is not clear to me right now is the interaction among autocast, DistributedDataParallel and optimizer weight updates. Suppose I am using bfloat16…

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Phylogenomic analysis, cryptic species discovery, and DNA barcoding of the genus Cibotium in China based on plastome data

Introduction Traditional Chinese herbal medicine plays an indispensable role in the treatment of multiple diseases in China and other developing countries (Newman et al., 2008). Apart from the traditional usage, many medicinal plants, such as Artemisia annua L. (artemisinin, Tu, 2016), Huperzia javanica (Sw.) C. Y. Yang (Huperzine A, Zangara, 2003;…

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Cogent Biosciences (COGT) Announces Positive Lead-In Data from Ongoing Phase 3 PEAK Trial of Bezuclastinib with Sunitinib

Get instant alerts when news breaks on your stocks. Claim your 1-week free trial to StreetInsider Premium here. Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined diseases, today announced positive lead-in data from its ongoing Phase 3 PEAK trial evaluating the selective…

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2023-06-03 | NDAQ:COGT | Press Release

– Data presented at ASCO annual meeting demonstrate 55% Disease Control Rate (DCR) in heavily pre-treated GIST patients, including 100% DCR and 17% overall response rate (ORR) in efficacy evaluable 2nd-line GIST patients; data immature to estimate progression free survival (PFS) – Combination of bezuclastinib and sunitinib is well-tolerated and…

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Cogent Biosciences Announces Positive Lead-In Data from

–  Data presented at ASCO annual meeting demonstrate 55% Disease Control Rate (DCR) in heavily pre-treated GIST patients, including 100% DCR and 17% overall response rate (ORR) in efficacy evaluable 2nd-line GIST patients; data immature to estimate progression free survival (PFS) –  Combination of bezuclastinib and sunitinib is well-tolerated and…

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Suid alphaherpesvirus 1 of wild boar origin as a recent source of Aujeszky’s disease in carnivores in Germany | Virology Journal

Davison AJ. Herpesvirus systematics. Vet. Microbiol. 2010;143:52–69. doi.org/10.1016/j.vetmic.2010.02.014 Article  CAS  Google Scholar  Mettenleiter TC, Ehlers B, Müller T, Yoon K, Teifke JP. Herpesviruses. In: Zimmerman, J., Karriker, L. A., Ramirez, A., Schwartz, K. J., Stevenson. G. W., editor. Diseases of Swine: John Wiley & Sons, Inc. Published 2012 by John…

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Bioinformatics Analyst I – RNA Biology Job in Texas

Summary Dr. Fazal is seeking a Bioinformatics Analyst I to develop and apply genomic analysis tools to identify cis- and trans- factors associated with RNA localization. The Fazal lab is a young laboratory focusing on systematically interrogating the subcellular transcriptomes of mammalian cells and characterizing the scope, regulation, and…

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Cogent Biosciences: APEX Part 2 Launched, ErbB2 And FGFR2 On Track (NASDAQ:COGT)

byakkaya Cogent Biosciences (NASDAQ:COGT) offers a compelling investment opportunity for those seeking exposure to a pioneering biotech company revolutionizing the development of precise therapies for genetically influenced diseases. By focusing on targeted treatments such as bezuclastinib and investigating novel ErbB2 and FGFR2 inhibitors, Cogent Biosciences showcases enormous potential in addressing…

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Things Phase 4 Did Perfectly

The one-two punch of Avengers: Infinity War and Avengers: Endgame firmly established the Marvel Cinematic Universe (MCU) as the biggest movie franchise in the world. What helped make the films among the biggest box-office hits ever is that they were the grand culmination of a decade’s worth of storytelling, as…

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A playground accident won’t stop our AADC deficiency therapy work

It took years of persuading our daughter, Rylae-Ann, to hop into the curved seat of the playground swing on her own and enjoy the freedom and weightlessness of swinging. When she turned 5 in April, we filmed and shared this significant achievement with family and friends after she finally took…

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UPSC Key- May 18, 2023: Know about Snow leopard project, 1.5 degrees, QUAD, DNA Vaccines, L-G and aldermen

FRONT PAGE L-G can destabilise elected MCD with power to nominate Preliminary Examination: Indian Polity and Governance-Constitution, Political System, Panchayati Raj, Public Policy, Rights Issues, etc. Main Examination: General Studies II: Functions and responsibilities of the Union and the States, issues and challenges pertaining to the federal structure, devolution of powers and…

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Mitogenomic phylogenetic analyses provide novel insights into the taxonomic problems of several hesperiid taxa (Lepidoptera: Hesperiidae)

Mitogenome features Nine new mitogenomes were assembled and annotated. Their circular maps were similar, thus only the map of Abraximorpha esta is shown (Fig. 1, Supplementary Fig. S1). The length of the mitogenomes ranged from the shortest, 15,284 bp (Coladenia maeniata) to the longest, 15,853 bp (Lotongus saralus chinensis and Trapezites iacchus). Each…

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expected scalar type half but found float [SOLVED]

The runtimeerror: expected scalar type half but found float error typically occurs when there is a mismatch between the data type expected by a PyTorch function and the actual data type of the tensor being passed as an argument. In this article, we will discuss the causes and provide some…

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Phase-3 Trial For Panacea Biotech’s Dengue Vaccine Likely From August-September

New Delhi: The phase-3 trial of a dengue vaccine developed by Panacea Biotech in collaboration with the Indian Council of Medical Research (ICMR) is likely to begin in August or September, a senior official said on Tuesday (May 16). Also, the phase 1/2 paediatric trials are underway for another dengue…

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Phase-3 trial for Panacea Biotech’s dengue vaccine likely from Aug-Sept

The phase-3 trial of a dengue vaccine developed by Panacea Biotech in collaboration with the Indian Council of Medical Research (ICMR) is likely to begin in August or September, a senior official said on Tuesday. Also, the phase 1/2 paediatric trials are underway for another dengue vaccine for which…

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Cogent Biosciences Reports Recent Business Highlights and First Quarter 2023 Financial Results

Cogent Biosciences, Inc. Lead-in data from Phase 3 PEAK trial to be presented at the American Society of Clinical Oncology (ASCO) 2023 Annual Meeting Announced initiation of APEX Part 2 expansion trial; on-track to present initial SUMMIT clinical data in 2H 2023 Ended 1Q 2023 with $220.3 million in cash,…

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Bioinformatics Analyst I – RNA Biology job with Baylor College of Medicine

Summary Dr. Fazal is seeking a Bioinformatics Analyst I to develop and apply genomic analysis tools to identify cis- and trans- factors associated with RNA localization. The Fazal lab is a young laboratory focusing on systematically interrogating the subcellular transcriptomes of mammalian cells and characterizing the scope, regulation, and function…

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What Is Focal Irreversible Electroporation?

Introduction IRE or irreversible electroporation, is a form of focal therapy that utilizes pulsatile electrical currents to remove or destroy tissues. This treatment is a promising option for patients with low or intermediate-risk prostate cancer or patients with a high cancer-risk progression. This treatment modality is still under research and…

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How to scale LLM workloads to 20B+ with Amazon SageMaker using Hugging Face and PyTorch FSDP

A couple of weeks ago, Together released an instruction-tuned large language model, fine-tuned for a chat from EleutherAI GPT-NeoX-20B with over 43 million instructions under an Apache-2.0 license! It is the first big open-source alternative to OpenAIs ChatGPT. The model might not perform as well as ChatGPT on your domain-specific…

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Problems in getting OpenAPI V3.0

I’ve recently upgraded from APEX V20.2 to APEX 22.2.3 The current ORDS (APEX_LISTENER) version is 20.4.1.r0131644 According to the docs I’ve red, this version supports generating the OpenAPI (swagger) documentation V3.0 version if you, in the header, set Accept: application/vnd.oai.openapi;version=3.0 I’ve tried with several tools to get the expected result…

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autocast with batch normalization in Pytorch model.eval() returns NaNs

I am working in Pytorch 2.0.0 Following the usual instructions for automatic mixed precision (AMP), training is done using # for autocasting scaler = torch.cuda.amp.GradScaler() ## …. for inputs, labels in loader: if inputs.device != device: inputs, labels = inputs.to(device), labels.to(device) ## modify to use autocasting as described at ##…

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Cogent Biosciences Presents Preclinical Data at AACR Annual

Preclinical data describes a novel EGFR-sparing, brain-penetrant ErbB2 inhibitor active against key oncogenic ErbB2 mutations In vivo characterization shows a novel, selective, reversible FGFR2 inhibitor has potency against molecular brake mutations and potential advantages over covalent approaches APEX Part 2 underway in AdvSM patients at once-daily 150 mg optimized dose…

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High Republic Phase 3 First Details

The High Republic is ready to make the leap to the Star Wars TV series world with The Acolyte, but before we see the final days of the Jedi’s apex, it’s time to see the explosive next step of their fight with Nihil in the third phase of the publishing…

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Uncovering biology by single-cell proteomics

To meet the challenge of sample depletion during preparation, there have been a number of recent advances in what is now a rapidly moving field of study of SCP, with important contributions from several investigators. Earlier work combined capillary electrophoresis (CE) with high-resolution mass spectrometry (HRMS) to analyze proteomes of…

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Pseudotemporal ordering of spatial lymphoid tissue microenvironment profiles trails Unclassified DLBCL at the periphery of the follicle

Abstract We have established a pseudotemporal ordering for the transcriptional signatures of distinct microregions within reactive lymphoid tissues, namely germinal center dark zones (DZ), germinal center light zones (LZ), and peri-follicular areas (Peri). By utilizing this pseudotime trajectory derived from the functional microenvironments of DZ, LZ, and Peri, we have…

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Ranjit Naiknavare elected as new President of CREDAI Pune Metro

Pune builder Ranjit Naiknavare has been elected unopposed as the president of the Pune division of the Confederation of Real Estate Developers Associations of India (CREDAI) Pune Metro. The CREDAI is the apex body for private Real Estate developers in India.  In the recently held meeting of the managing committee,…

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The oldest case of paedomorphosis in rove beetles and description of a new genus of Paederinae from Cretaceous amber (Coleoptera: Staphylinidae)

Conditions leading to size reduction and morphological modifications Because of the uncommon combination of morphological features found in Midinudon juvenis Tokareva & Żyła gen. et sp. nov., we hypothesise that the species has been affected by several evolutionary processes resulting in size reduction as well as the display of paedomorphic…

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Two florigens and a florigen-like protein form a triple regulatory module at the shoot apical meristem to promote reproductive transitions in rice

Andrés, F. & Coupland, G. The genetic basis of flowering responses to seasonal cues. Nat. Rev. Genet. 13, 627–639 (2012). Article  PubMed  Google Scholar  Komiya, R., Ikegami, A., Tamaki, S., Yokoi, S. & Shimamoto, K. Hd3a and RFT1 are essential for flowering in rice. Development 135, 767–774 (2008). Article  CAS …

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python – PyTorch with Transformer – finetune GPT2 throws index out of range Error

in my Jupiter i have the following code. I can not figure out why this throws a IndexError: index out of range in self error. here ist the code: !pip install torch !pip install torchvision !pip install transformers import torch from torch.utils.data import Dataset class MakeDataset(Dataset): def __init__(self, tokenized_texts, block_size):…

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Johnson & Johnson’s dengue antiviral drug shows positive results

Novel anti-viral drug developed by Johnson & Johnson (J&J) arm Janssen Pharmaceutical provides “strong protection” against dengue in non-human primates and mice, early stage clinical data published in ‘Nature’ journal has revealed. “The first-in-class antiviral, which was shown to be safe and…

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