Tag: apollo

Onpattro shows benefits for 1.5 years in ATTR cardiomyopathy trial | Therapy seen to slow down disability in people with ATTR-CM

Treatment with Onpattro (patisiran) for 1.5 years leads to sustained reductions in disability progression among people with ATTR amyloidosis with cardiomyopathy (ATTR-CM), or damage to the heart. That’s according to interim data from the ongoing open-label extension (OLE) portion of the Phase 3 APOLLO-B clinical trial (NCT03997383). That trial’s initial…

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Patisiran Benefits Maintained Over 18 Months in Patients With Transthyretin Amyloidosis

The long-term extension of the phase 3 APOLLO-B study confirmed the efficacy and safety of patisiran in patients with transthyretin (ATTR) amyloidosis and highlights the importance of early treatment. Functional capacity, health status, and quality of life were preserved throughout the follow-up period. ATTR amyloidosis is a progressive and fatal…

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Alnylam Pharma Presents 18-Month Results from the APOLLO-B Phase 3 Study of Patisiran By Investing.com

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced new results from an interim analysis of exploratory data from the open-label extension (OLE) period of the APOLLO-B Phase 3 study of patisiran, an investigational RNAi therapeutic in development for the treatment of transthyretin-mediated (ATTR) amyloidosis with cardiomyopathy….

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Alnylam Presents 18-Month Results from the APOLLO-B Phase 3 Study of Patisiran in Patients with ATTR Amyloidosis with Cardiomyopathy

– Continued Treatment with Patisiran in Open-Label Extension Period Showed Evidence of Sustained Benefit across Measures of Functional Capacity and Health Status and Quality of Life, as well as Cardiac Stress and Injury, through 18 Months – – Safety Profile Consistent with that Observed in 12-Month Double-Blind Period, with No…

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2023-05-20 | NDAQ:ALNY | Press Release

– Continued Treatment with Patisiran in Open-Label Extension Period Showed Evidence of Sustained Benefit across Measures of Functional Capacity and Health Status and Quality of Life, as well as Cardiac Stress and Injury, through 18 Months – – Safety Profile Consistent with that Observed in 12-Month Double-Blind Period, with No…

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Revyve Clinic introduces cutting-edge technologies for advanced aesthetic treatments

ANI | Updated: May 16, 2023 15:12 IST Faridabad (Haryana) [India], May 16 (ANI/PNN): Revyve Clinic, the renowned center for skin and hair treatment, is set to revolutionize the aesthetic industry with the introduction of the latest and fastest technologies in the field. Dr Sandeep Babbar, the esteemed dermatologist and…

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Is Electrical Duodenal Resurfacing the Next Big Thing for T2D and Obesity?

CHICAGO — A novel approach to revitalizing the duodenal mucosa as a means to restore normal insulin sensitivity in people with type 2 diabetes is showing strong promise in early studies, according to results presented here. In two single-arm trials of a system called ReCET, reported at Digestive Disease Week…

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AAN 2023: Amvuttra and Onpattro show similar efficacy as FAP treatments | Comparable, sustained drops in transthyretin levels seen

Amvuttra (vutrisiran) and Onpattro (patisiran) showed similar safety and efficacy for familial amyloid polyneuropathy (FAP) patients, according to new analyses from the Phase 3 HELIOS-A trial that supported Amvuttra’s regulatory approval. Both therapies led to similar reductions in transthyretin, the protein that accumulates in FAP, and they were associated with comparable…

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China to establish organization to coordinate international moon base

HELSINKI — China National Space Administration will soon set up an organization to oversee and coordinate the China-led International Lunar Research Station. Wu Weiren, Director General of the Deep Space Exploration Laboratory (DSEL), said during an exploration conference April 25 that the International Lunar Research Station Cooperation Organization (ILRSCO) would…

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Genomics has enormous potential towards personalised, preventive healthcare, says Governor

Governor R.N. Ravi at the inauguration of the Apollo Genomics Institute in Chennai on Tuesday. Also seen, from left, are Sandi Deans, National Laboratory and Scientific Lead (Genomics), NHS England; Preetha Reddy, vice-chairperson, Apollo Hospitals; Prathap C. Reddy, chairman, Apollo Hospitals Group; and Suneeta Reddy, managing director, Apollo Hospitals. |…

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Apollo to set up more genomics institutes by 2023-end

Healthcare major Apollo Hospitals Group has drawn up plans to set up three more genomic facilities in the country, a senior official said here on Tuesday. Earlier in the day, Tamil Nadu Governor R N Ravi inaugurated the Apollo Genomic Institute in Chennai in the presence of chairman…

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19 Ways AI May Soon Revolutionize The Healthcare Industry

getty Technology experts are clear: Artificial intelligence is poised to revolutionize procedures and tasks across industries—and healthcare is no exception. While it’s not anticipated that AI can ever replace human doctors’ intelligence, empathy and reasoning, tech experts say it can provide invaluable assistance in a variety of health applications. From…

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Checklist from last Apollo lunar mission sells for almost US$800,000

A piece of space history has sold at auction for US$744,994 after the moondust-besmirched checklist Apollo 17 Commander Gene Cernan wore on his spacesuited wrist during the last crewed lunar mission went on the block at RR Auctions. Previously sold in 2021, the checklist was worn by Cernan on the…

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Merck acquires Prometheus Biosciences in $10.8bn deal

Prometheus’ lead candidate, PRA023, is a humanized monoclonal antibody (mAb) being development to treat immune-mediated diseases including ulcerative colitis (UC) and Crohn’s disease (CD). Founded in 1995, the company also has a second candidate in Phase 1 trials and three others in pre-clinical development. Phase 3 trials planned Merck, known…

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Amazon Has Bad News for Workers Everywhere (Not Just Amazon Employees)

Just since you do not work for Amazon does not imply this main change will not make your life worse. Before the covid pandemic, unemployment hovered round all-time lows which compelled firms to make worker-friendly concessions. That’s if you noticed retailers like Walmart (WMT) – Get Free Report and Target…

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How the Human Genome Project revolutionised biology

Big is beautiful. That was the message of post-second-world-war science. The model was the Manhattan Project, to build the first atom bombs. When hostilities ended, it continued with larger and larger particle accelerators, to probe matter at smaller and smaller scales—and bigger telescopes to do that probing at the largest…

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Inside the (Deep) Mind of Demis Hassabis

He wrote computer games at 8; became a chess prodigy at 14; created Theme Park, one of the first video games to incorporate AI, at 17; took a double first in computer science from Cambridge at 20; founded a groundbreaking video-game company at 22. Who, but Demis Hassabis, could have…

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Dangerous plant fungus infects man in first-known global case, doctors say

article Sabouraud dextrose agar showed growth of creamy pasty colony with buff coloured pigmentation on reverse side after 4–5 days. (Soma Dutta, Ujjwayini Ray) A man in India stumped doctors after his throat sores became documented as the world’s first case of a potentially deadly fungal infection caused by plants….

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Silence Therapeutics Stock: A Speculative Buy (NASDAQ:SLN)

Evgenii Kovalev Background Silence Therapeutics (NASDAQ:SLN) is a UK-based biotechnology company specializing in RNA interference [RNAi] technology. The company is focused on developing and commercializing a pipeline of therapies using its proprietary platform technology to target and silence disease-causing genes. Silence Therapeutics has a diversified pipeline of preclinical and clinical…

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How Pure Storage Flash Powered Infection Disease Research

The McArthur Lab at McMaster University is a different kind of frontline fighter. The research facility fights to save lives by sequencing genomes and pathogens and studying massive datasets. Over the years, the lab has developed the world’s largest database of data related to drug-resistant infections. McArthur Lab’s genomic datasets…

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Leveraging Early Cancer Detection Tech

Cancer is fast turning into an ‘epidemic’ and is the second leading cause of death globally. As per the Globocan Report of 2020, the annual global burden of cancer in 2020 in the country had hit the 1.93 crore mark with an annual death of 1 crore. Let’s explore some…

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a “once in a lifetime opportunity” in 2023

Investments banks may be cutting pay and jettisoning humans in 2023, but not all financial services jobs are shrinking. Speaking at the London School of Economics’ (LSE) Alternative Investments Conference, investors working in private credit said their area of the market is in its element. Charlotte Muellers, co-head of North America…

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24 groundbreaking events that happened during the Queen’s reign

When Queen Elizabeth was crowned in 1953, she promised to rule for her whole life. It was a commitment that never waivered and saw her on the throne for more than 70 years, over which time the world changed significantly. During her reign, the Queen saw some of the most…

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Most advanced professional Aesthetic Medical Devices

WEERO is a global manufacturer to provide most advanced and the newest aesthetic medical device and beauty device to the world. The company name of WEERO means warm and upward.  WEERO is continuing to research and develop the most cutting edge technologies to stay ahead of the market, and always…

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NIPT Testing For Pregnant Women

By Dr Niranjan Nayak, Consultant pathologist zonal technical chief west, Apollo diagnostic Pune Are you aware? Non-invasive Prenatal Testing (NIPT) means a screening test that can be done commonly in the first 3 months of pregnancy to detect chromosomal abnormalities in the baby. This test detects the 3 commonly occuring…

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Joey Holder | Apollo 40 Under 40 Art & Tech | In Focus

London and Nottingham For her first solo show at Seventeen Gallery in London, which took place this past spring, Joey Holder immersed visitors in an eerie virtual world in which H.R. Giger-esque computer-generated creatures wriggle and writhe – a seemingly extraterrestrial landscape, lit in cool blues and greens and soundtracked…

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Colossal launches with $15 million to bring back woolly mammoths

Harvard scientist George Church, a pioneer of both DNA sequencing and gene editing, has been talking in the press for more than a decade about the possibility of bringing the extinct woolly mammoth back to life. It’s been the subject of magazine articles, books, and, of course, a TEDx talk….

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Eukaryotic Annotation Team Leader job with EMBL

We are seeking a faculty-level genome scientist to lead the Eukaryotic Annotation Team at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI).  As Team Leader you will have strategic responsibility for gene annotation and comparative genomics in the Ensembl project, and also lead the EMBL contribution to a portfolio…

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