Tag: biorender
CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination
Abstract Background A barrier to HIV-1 cure rests in the persistence of proviral DNA in infected CD4+ leukocytes. The high HIV-1 mutation rate leads to viral diversity, immune evasion, and consequent antiretroviral drug resistance. While CRISPR-spCas9 can eliminate latent proviral DNA, its efficacy is limited by HIV strain diversity and…
Shaping modern human skull through epigenetic, transcriptional and post-transcriptional regulation of the RUNX2 master bone gene
Study of RUNX2 locus in modern and ancient humans The sequences of the RUNX2 locus (Chr6:45,318,000–45,670,000 hg38, for a total of 352.000 bases) have been aligned in AMH and ancient species’ (Neandertal and Denisovan) genomes to map the changes occurred during recent evolution. We have identified 459 and 470 changes…
Genetic Factors Affecting Precision Pain Medicine
Introduction The overarching definition of precision pain medicine is that diagnosis and treatment can be customized to an individual’s specific risk profile.1,2 At its most basic, the ideology is based on using all available patient-level data to target therapies for that individual with regard to prediction, prevention, diagnosis, and treatment…
free online tools to build scientific figures/tables for journal/thesis
free online tools to build scientific figures/tables for journal/thesis 0 Dear All, What are some free and good online tools/websites to prepare scientific illustrations for publications/thesis and presentations ?I have heard of BioRender and google gives quite an extensive list. Thank you illustrations scientific figures • 31 views • link…
