Tag: blaCTX-M-55

ST23 Klebsiella pneumoniae in China

Introduction Klebsiella pneumoniae (KP), a member of the Enterobacteriaceae family, inhabits aquatic environments and can colonise respiratory and gastrointestinal tracts in humans, making it a significant opportunistic pathogen. It may result in pneumonia, meningitis, urinary tract infections, and bloodstream infections. Hypervirulent Kp (HvKp) is believed to cause severe community-acquired invasive…

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Leveraging the COVID-19 pandemic as a natural experiment to assess changes in antibiotic use and antibiotic-resistant E. coli carriage in semi-rural Ecuador

Knight, G. M. et al. Antimicrobial resistance and COVID-19: Intersections and implications. Elife doi.org/10.7554/eLife.64139 (2021). Article  PubMed  PubMed Central  Google Scholar  Bong, C.-L. et al. The COVID-19 pandemic: Effects on low- and middle-income countries. Anesth. Analg. 131(1), 86–92. doi.org/10.1213/ANE.0000000000004846 (2020). Article  CAS  PubMed  Google Scholar  Alhalaseh, Y. N. et al….

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Machine learning and metagenomics reveal shared antimicrobial resistance profiles across multiple chicken farms and abattoirs in China

Wu, Z. Antibiotic Use and Antibiotic Resistance in Food-Producing Animals in China OECD Food, Agriculture and Fisheries Paper No. 134 (OECD, 2019); doi.org/10.1787/4adba8c1-en Looft, T. et al. In-feed antibiotic effects on the swine intestinal microbiome. Proc. Natl Acad. Sci. USA 109, 1691–1696 (2012). Article  ADS  CAS  PubMed  PubMed Central  Google…

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Whole strains vs MGEs in short and longterm transmission of ESBL genes between healthcare and community settings in Uganda

ESBL carriage Of the 1556 samples analyzed, 81.9% (1275) yielded suspected ESBL producing bacteria. The antimicrobial susceptibility testing of the obtained isolates showed that many of the strains were resistant to critical cephalosporin and carbapenem antimicrobials such as Cefepime, Cefotaxime, Cefoxitin, Ceftazidime, Ertapenem and Imipenem in both healthcare and community…

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Genomic characteristics of ESBL-producing E. coli in China

Introduction Currently, the emergence of bacterial resistance poses a significant challenge to public health worldwide. With the widespread use of antimicrobial agents in recent years, the isolation of multidrug-resistant Escherichia coli has increased yearly, particularly among Extended Spectrum β-lactamases (ESBLs) producing strains, which can cause not only multi-site infections but…

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Evidence of international transmission of mobile colistin resistant monophasic Salmonella Typhimurium ST34

Three samples of S. 4,[5],12:i:-, all isolated in 2010, harbored mcr-3.1. Two were from human stool and the other was from ready-to-eat frozen food. Phenotypic characterization confirmed that all three isolates were resistant to colistin, all with MIC and MBC of 8 µg/ml. WGS of H1-012, H1-014 and H1-120 were analyzed…

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Whole genome sequence analysis of the first reported isolate of Salmonella Agona carrying blaCTX-M-55 gene in Brazil

Bacterial isolate Adolfo Lutz Institute is a regional reference laboratory for Salmonella isolates from São Paulo, Brazil. Thus, all isolates received are submitted to classical serotyping, antimicrobial susceptibility testing, and molecular-typing by PFGE and next-generation sequencing. Isolate 288_18 was recovered from a blood sample from a patient with clinical symptoms…

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Rapid emergence of extensively drug-resistant Shigella sonnei in France

Antimicrobial susceptibility data of S. sonnei in France Our review of S. sonnei antimicrobial susceptibility data obtained between 2005 and 2021 (based on 7121 isolates received and confirmed at the French National Reference Center for E. coli, Shigella and Salmonella, FNRC-ESS, Institut Pasteur) revealed a sharp increase in the percentage…

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Geography shapes the genomics and antimicrobial resistance of Salmonella enterica Serovar Enteritidis isolated from humans

Sample dataset description To reconstruct the phylogeny of S. Enteritidis human isolates in a global context, 159 genomes of S. Enteritidis from different countries were selected and downloaded from our initial query of public data in addition to the 16 S. Enteritidis genomes our laboratory sequenced in the study. In…

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Extensively drug resistant E. coli LZ00114

Introduction Escherichia coli is a common Gram-negative opportunistic pathogen that causes invasive host infections through virulence factors such as flagella, toxin secretion, and adhesins. According to the source of the infection, pathogenic E. coli can be classified as intestinal (diarrheagenic) and extraintestinal (ExPEC). Uropathogenic E. coli (UPEC) is the most…

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Emergence of the Coexistence of mcr-1, blaNDM-5, and blaCTX-M-55 in Kl

Introduction Klebsiella pneumoniae (K. pneumoniae) is an opportunistic pathogen and the leading cause of healthcare-associated infections.1 Multidrug-resistant (MDR) K. pneumoniae isolates are rapidly spreading, thus limiting the choice of antimicrobial agents for empiric treatment of infections caused by these microorganisms; hence, this is a public health challenge.2 Polymyxins are last-resort…

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