Tag: CDC
bioinformatics jobs work from home
Lamentamos pelo inconveniente. University of Arizona Tucson, AZ (Onsite) Full-Time. Experience in conducting laboratory work by utilizing tools in molecular biology and microbiology. Sie weiterhin diese Meldung erhalten, informieren Sie uns darber bitte per E-Mail Se continui a visualizzare The Bioinformatics Analyst position will work closely with the PI and…
Shionogi Enrolls the First Participant in Japan in its Global Phase 3 Trial of Ensitrelvir for the Prevention of Symptomatic SARS-CoV-2 Infection | News
OSAKA, Japan–(BUSINESS WIRE)–Jun 9, 2023– Shionogi & Co., Ltd. (Head Office: Osaka, Japan; Chief Executive Officer: Isao Teshirogi, Ph.D.; hereafter “Shionogi”) today announced the first participant has been enrolled in Japan in its global Phase 3 study, S topping CO VID-19 p R ogression with early P rotease I nhibit…
Astellas developing new gastric cancer drug
Astellas Pharma Inc. has submitted a new drug application (NDA) to Japan’s Ministry of Health, Labour and Welfare (MHLW) for zolbetuximab. Zolbetuximab is a first-in-class investigational Claudin 18.2 (CLDN18.2)-targeted monoclonal antibody, for first-line treatment of patients with locally advanced unresectable or metastatic HER2-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma whose…
Cingulate Completes Phase 3 Adult Trial of CTx-1301 (dexmethylphenidate) for ADHD
Study Assessed Onset and Duration of CTx-1301 in Adults, Results Expected 3Q 2023 Pivotal Phase 3 Trials in Pediatric/Adolescent Patients on Schedule for 3Q 2023 Initiation KANSAS CITY, Kan., June 08, 2023 (GLOBE NEWSWIRE) — Cingulate Therapeutics Inc. (NASDAQ: CING), a biopharmaceutical company utilizing its proprietary Precision Timed Release™ (PTR™)…
Biomarker Testing Services Market Size To See Booming Growth
PRESS RELEASE Published June 8, 2023 The most recent study conducted by Report Ocean, titled “Global Biomarker Testing Services Market Size, Share, Pricing, Trends, Growth, Report and Forecast 2023-2030,” presents a comprehensive analysis of the worldwide market. This research delves into the factors driving the market, emerging trends, opportunities for…
Cingulate Completes Phase 3 Adult Trial of CTx-1301
Study Assessed Onset and Duration of CTx-1301 in Adults, Results Expected 3Q 2023 Pivotal Phase 3 Trials in Pediatric/Adolescent Patients on Schedule for 3Q 2023 Initiation KANSAS CITY, Kan., June 08, 2023 (GLOBE NEWSWIRE) — Cingulate Inc. (NASDAQ: CING), a biopharmaceutical company utilizing its proprietary Precision Timed Release™ (PTR™) drug…
Strengthening agricultural systems through plant-breeding and tools for farmers
Open this photo in gallery: Efforts to improve outcomes for farmers, such as the Kernen Farm, at the University of Saskatchewan’s Crop Development Centre include research on disease pressures on wheat and pea crops and plant breeding.AIRSCAPES Farm productivity is subject to a complex web of conditions. On the economic…
Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children | Malaria Journal
WHO. World malaria report 2021. Geneva: World Health Organization; 2021. Google Scholar CDC, Global. COVID-19: centres for disease control and prevention; 2021. www.cdc.gov/coronavirus/2019-ncov/global-covid-19/index.html. Accessed 14 Dec 2021. Sidhu ABS, Valderramos SG, Fidock DA. Pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Mol Microbiol. 2005;57:913–26. Article …
[Full Time] Senior Bioinformatics Engineer at Ginkgo Bioworks (United States)
Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Ginkgo…
A case report of cutaneous anthrax diagnosed with mNGS
Yushan Liu,1,2 Gezhi Zheng,1,3 Jing Li,1,3 Nan Yang,1– 4 Juan Li,1,2 Zhengwen Liu,1– 4 Qunying Han,1– 4 Yingren Zhao,1– 4 Fenjing Du,1,3 Yingli He,1,* Taotao Yan1,* 1Department of Infectious Diseases, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 2Institution of Hepatology, The First Affiliated…
Composition of Anopheles species and bionomic characteristics over the peak malaria transmission season in Bandarban, Bangladesh | Malaria Journal
WHO. World malaria report 2022. Geneva: World Health Organization; 2022. Google Scholar Haque U, Overgaard HJ, Clements AC, Norris DE, Islam N, Karim J, et al. Malaria burden and control in Bangladesh and prospects for elimination: an epidemiological and economic assessment. Lancet Glob Health. 2014;2:e98–105. Article PubMed Google Scholar Alonso…
Ginkgo Bioworks Senior Bioinformatics Engineer
Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Ginkgo Bioworks…
How genome sequences tracked down an ancient disease
This article is part of a fortnightly column exploring contemporary concepts and issues in genetics. The ‘black death’, or the Great Plague, of the 14th century was one of the deadliest epidemics in human history. It’s a clear example of the profound influence infectious disease outbreaks can have on society,…
Characterization of metagenome-assembled genomes from the International Space Station | Microbiome
Metagenome-assembled bacterial genomes Out of the 42 ISS metagenomes submitted at NCBI, only PMA-treated metagenomes (n = 21) representing the viable/intact cells were used for generating bacterial MAGs. Characteristics of MAGs (n = 46) such as genome size (2.6 to 6.6 Mb), completeness, contamination percentage, the average mean coverage, number…
Whole-genome sequencing of Listeria monocytogenes isolated from the first listeriosis foodborne outbreak in South Korea
Introduction Although globalization has provided opportunities for consumers to enjoy a wide range of products and expanded global food trade, the complexity of the international food supply has contributed to an increase in foodborne outbreaks (Quested et al., 2010; Hussain and Dawson, 2013). Worldwide efforts have ensured food safety by…
FDA Approves Pfizer’s ABRYSVO Vax For RSV Prevention
Pfizer received approval from the FDA for ABRYSVO (Respiratory Syncytial Virus Vaccine), the company’s bivalent RSV prefusion F (RSVpreF) vaccine, for the prevention of lower respiratory tract disease caused by RSV in individuals 60 years and older. ABRYSVO is unadjuvanted and composed of two preF proteins selected to optimize protection…
How to ‘build a better NIH’
Comment on this storyComment Welcome to Wednesday, where your guest author is in search of a TV show to replace “Succession” as his weekly escape. Send viewing suggestions and other tips to dan.diamond@washpost.com. Not a subscriber? Sign up here. Today’s edition: The debt ceiling bill goes before the full House…
the monitor in mcallen, texas obituaries
If you are interested in reading The Monitor McAllen Texas obituaries, you can find them online or in the print edition of the newspaper. Learn About Online Memorials 269 talking about this. I was honored to have known Jeannie while living and growing up in McAllen. Mrs. Stroud, may you…
TheStreetReports: AI Biomedical Companies Disrupting Healthcare: INBS, DNA, IBRX, CDIO
PRESS RELEASE Published May 30, 2023 Artificial Intelligence (AI) technology is disrupting many industries. One of those is healthcare and specifically the biomedical space. Data Bridge Market Research reported in 2022 that the healthcare-related AI market was expected to grow at a CAGR of 51.37% and hit a valuation of…
Pfizer Announces Positive Marstacimab Results from Pivotal Phase 3 Hemophilia A and B Trial
Study demonstrates statistically significant and clinically relevant reduction in annualized bleeding rate compared to prophylaxis and on-demand intravenous regimens Marstacimab, if approved, has the potential to become the first once-weekly subcutaneous treatment for people living with hemophilia B and the first treatment administered as a flat dose for people living…
Plasmid DNA Manufacturing To See Impressive Growth In Years Ahead
By Sharvari Rale, Fairfield Market Research The quest for the most effective disease treatments has become more urgent than ever. The global chronic disease burden is swelling at alarming rates, pointing to growing severity of the situation for the global healthcare system, economy, and public health. Prevalence of chronic conditions…
Dna Digital Data Storage Market Global Demand, Sales Revenue
According to Premium Market Insights new research study on “DNA Digital Data Storage Market is expected to grow from US$ 57.81 million in 2021 to US$ 1,761.49 million by 2028; it is estimated to grow at a CAGR of 61.29% during 2021-2028. Get a Sample Copy of This Report@ www.premiummarketinsights.com/sample/TIP00073351/?utm_source=OpenPR&utm_medium=10655…
Measuring Risk Factors of Developing SCLC
Qian Wang, MD, MPH, assistant professor at Case Western Reserve University, thoracic oncologist at University Hospital Siteman Cancer Center, discusses the relevant metrics to determine the risk factor of developing small cell lung cancer (SCLC). SCLC accounts for about 50% of all cases of lung cancer, with smoking being the…
Scientists develop new gene editing tool that may help reduce spread of antimicrobial resistance
A microscopic image of virus (Photo credit: CDC) According to the World Health Organization, antimicrobial resistance poses a serious threat to everyone on the planet, with approximately five million people dying each year because infections cannot be treated with antibiotics A novel gene-editing tool that researchers have created may help…
Could new Lyme disease tests help to prevent chronic infection?
Lyme disease is the most common vector-borne disease in the U.S. – a new CDC estimate suggests that approximately 476,000 Americans are diagnosed with Lyme disease each year – and it is caused by the bacterium Borrelia burgdorferi. It is primarily transmitted to humans through the bite of an infected…
Pentavalent meningitis vaccine continues to show promise in phase 3 trial
Source/Disclosures Disclosures: Haidara and Stephens report no relevant financial disclosures. Please see the study for all other authors’ relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to…
First new ‘quit-smoking’ drug in 20 years shows promising results in US trial: ‘Hope and excitement’
A new drug may be on the horizon to help people kick the world’s deadliest habit. Achieve Life Sciences, Inc., a Seattle, Washington-based pharmaceutical company, has announced positive results from the Phase 3 trial of a drug called cytisinicline. Smoking claims more than seven million lives each year worldwide, making…
First new ‘quit-smoking’ drug in 20 years shows promising results in US trial: ‘Hope and excitement’
A new drug may be on the horizon to help people kick the world’s deadliest habit. Achieve Life Sciences, Inc., a Seattle, Washington-based pharmaceutical company, has announced positive results from the Phase 3 trial of a drug called cytisinicline. Smoking claims more than seven million lives each year worldwide, making…
CDC updates Papa Murphy’s Salmonella Cookie Dough Outbreak
18 with Salmonella Enteritidis in Washington, Oregon, California, Idaho, Utah and Missouri. “Cookie Dough has been an ongoing Salmonella risk to consumers,” said William Marler. “However, in recent years the suspected contaminated ingredient as turned from eggs to flour, which to most consumers is both unsettling and unusual,” added Marler. CDC, public…
Rakuten Medical to Start a Global Phase 3 Trial of Alluminox Treatment Using ASP1929 for Recurrent Head and Neck Cancer in India
India: Rakuten Medical, Inc. (Rakuten Medical), a global biotechnology company developing and commercializing precision, cell-targeting therapies based on its proprietary Alluminox™ platform, today announced that the Company has been granted permission from the Indian Central Drugs Standard Control Organization (CDSCO) to conduct its global, pivotal…
A global dataset of sequence, diversity and biosafety recommendation of arbovirus and arthropod-specific virus
Generally, there are two major groups of viruses that circulate in hematophagous arthropods: arthropod-borne virus (arbovirus) and arthropod-specific virus (ASV) (or arthropod-only virus). These viruses are diverse in taxonomy and may have unsegmented or segmented (two to twelve) genomes. Arbovirus are transmitted by hematophagous arthropods such as mosquitoes, ticks, sandflies,…
FDA Advisory Committee Votes in Support of Approval for Pfizer’s Vaccine Candidate to Help Prevent RSV in Infants Through Maternal Immunization
The positive vote is based on compelling scientific evidence presented, including Phase 3 efficacy and safety data in pregnant individuals and their infants FDA decision expected in August 2023 If authorized, the vaccine candidate would help protect infants at first breath through six months of life against RSV disease and…
Ipsen completes acquisition of Epizyme expanding its portfolio in oncology
Ipsen Pharma PARIS, FRANCE, 12 August 2022 – Ipsen (Euronext: IPN; ADR: IPSEY) today announced the closing of the definitive merger agreement under which Ipsen has acquired Epizyme, Inc. (Epizyme). Pursuant to the transaction, Ipsen acquires all outstanding shares of Epizyme for $1.45 per share plus a contingent value right (CVR)…
Statement on the antigen composition of COVID-19 vaccines
The WHO Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) continues to meet regularly to assess the implications of SARS-CoV-2 evolution for COVID-19 vaccine antigen composition and advise WHO on whether changes are needed to the antigen composition of future COVID-19 vaccines. In April 2023, the TAG-CO-VAC indicated that the…
Ipsen completes acquisition of Epizyme expanding its
PARIS, FRANCE, 12 August 2022 – Ipsen (Euronext: IPN; ADR: IPSEY) today announced the closing of the definitive merger agreement under which Ipsen has acquired Epizyme, Inc. (Epizyme). Pursuant to the transaction, Ipsen acquires all outstanding shares of Epizyme for $1.45 per share plus a contingent value right (CVR) of $1.00…
Microorganisms | Free Full-Text | Whole-Genome Sequencing of Shiga Toxin-Producing Escherichia coli for Characterization and Outbreak Investigation
1. Introduction Shiga toxin-producing Escherichia coli (STEC) is a Gram-negative foodborne pathogen that was estimated to cause ~265,000 infections, 3600 hospitalizations, and 30 deaths in the U.S. each year [1]. Most patients with STEC infections develop diarrhea and abdominal pain, though hemolytic uremic syndrome (HUS) and kidney failure can occur,…
Innoviva (INVA) Announces Publication of Results from Phase 3 ATTACK Trial
Get instant alerts when news breaks on your stocks. Claim your 1-week free trial to StreetInsider Premium here. Innoviva Specialty Therapeutics, a subsidiary of Innoviva, Inc. (Nasdaq: INVA) focused on delivering innovative therapies in critical care and infectious disease, today announced that The Lancet Infectious Diseases published detailed results from…
2023-05-11 | NDAQ:INVA | Press Release
Sulbactam-durlobactam is the first pathogen-targeted therapy under investigation for the treatment of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by susceptible strains of Acinetobacter baumannii-calcoaceticus complex (Acinetobacter). Innoviva Specialty Therapeutics, a subsidiary of Innoviva, Inc. (Nasdaq: INVA) focused on delivering innovative therapies in critical care and infectious disease, today…
How African scientists are working to pool data that decodes diseases
Credit: Pixabay/CC0 Public Domain Infectious disease outbreaks in African countries are, unfortunately, all too common. Ebola in the Democratic Republic of the Congo or Uganda; Marburg virus in Guinea or Equatorial Guinea; cholera in Malawi; malaria and tuberculosis are among them. These diseases do not respect human-made or porous borders….
Results from Pivotal Phase 3 ATTACK Trial of Investigational Sulbactam-Durlobactam for Treatment of Serious Infections Caused by Acinetobacter Published in The Lancet Infectious Diseases
WALTHAM, Mass., May 11, 2023–(BUSINESS WIRE)–Innoviva Specialty Therapeutics, a subsidiary of Innoviva, Inc. (Nasdaq: INVA) focused on delivering innovative therapies in critical care and infectious disease, today announced that The Lancet Infectious Diseases published detailed results from the pivotal Phase 3 ATTACK trial of sulbactam-durlobactam, the first pathogen-targeted therapy being…
Hospital Surveillance Sequencing Helps Link Cases to Nationwide Contaminated Eyedrop Outbreak
NEW YORK – A whole-genome sequencing (WGS)-based hospital outbreak surveillance program has helped researchers at the University of Pittsburgh to identify two drug-resistant Pseudomonas aeruginosa infections associated with a national outbreak of contaminated eyedrops. While the cases were ruled out as in-hospital transmissions, the findings illustrate the potential value of…
News at a glance: A respiratory disease vaccine, observing intensifying cyclones, and shaking a tall wooden building | Science
ENGINEERING Tall wood building is shaken, but not scathed A 10-story wooden building survived two severe, simulated earthquakes intact this week as scientists sought to show that wood can rival steel and concrete to safely support tall buildings. The structure is the tallest ever tested at the University of California,…
African scientists are working to pool data that decodes diseases — a giant step
Infectious disease outbreaks in African countries are, unfortunately, all too common. Ebola in the Democratic Republic of the Congo or Uganda; Marburg virus in Guinea or Equatorial Guinea; cholera in Malawi; malaria and tuberculosis are among them. These diseases do not respect human-made or porous borders. So it’s essential that…
Experts call for monitoring of respiratory va
Experts have called for further scrutiny of a new Pfizer vaccine given during pregnancy to prevent respiratory infection in infants, after trials of a similar GSK vaccine were stopped after a rise in preterm birth and infant deaths. Pfizer says its vaccine is safe and effective, but experts contacted as part…
Cost-benefit analysis supports adoption of routine genetic testing
After conducting a cost-benefit analysis of population genetic testing, study investigators are recommending that U.S. health policymakers adopt routine genetic testing of all adults ages 40 and under for three genetic conditions posing a high risk of life-threatening illness. The research, published Tuesday in the journal Annals of Internal Medicine,…
Diagnostics | Free Full-Text | Application of Hybridization Chain Reaction/CRISPR-Cas12a for the Detection of SARS-CoV-2 Infection
1. Introduction The World Health Organization (WHO), on 11 March 2020, declared the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a pandemic [1,2]. The causative virus is a newly discovered pathogenic member of the beta coronavirus genus, which causes the coronavirus disease 2019 (COVID-19). The pathogen has primarily been…
Global mpox lineage discovery and rapid outbreak tracking with nanopore sequencing | Virology Journal
Targeted amplicon paneling and nanopore sequencing A set of primer pools, protocols, and computational commands were designed to sequence hMPXV1 genomes on a MinION nanopore flow cell (Fig. 2A). All necessary protocols are briefly described in the Methods section and available as Additional file 2: Working Laboratory Protocols. Initial amplicon primers…
Detection of Burkholderia pseudomallei with CRISPR-Cas12a based on specific sequence tags
1. Introduction Melioidosis is a tropical disease caused by the aerobic, Gram-negative motile bacillus which is classified as a category B biological agent by the Centers for Disease Control and Prevention (CDC) of America (1, 2). It is a highly pathogenic endemic zoonotic disease in many tropical countries, particularly in…
California’s first CDC-confirmed case of Borrelia miyamotoi
A recent case reminds us that Lyme disease isn’t the only tick-borne disease we need to worry about. Last year, the CDC confirmed California’s first known case of Borrelia miyamotoi—a tick-borne pathogen that causes a relapsing-fever illness in humans. This discovery highlights the need for increased awareness and surveillance of…
Improving the Potency of Monoclonal Antibodies With Fucosylation
Early on, one of the central challenges in mAb production was low product titer – but this has since been overcome by advances in cell line development and substantial improvements in cell-specific productivity, and further driven by broader progress in industrial bioproduction technology. Bioprocess optimization, generally achieved via optimization of…
Enzymatic DNA Synthesis Global Market Report 2023: Growing
Dublin, May 02, 2023 (GLOBE NEWSWIRE) — The “Enzymatic DNA Synthesis Market Forecast to 2028 – COVID-19 Impact and Global Analysis By Product Type, Application, End User, and Technology” report has been added to ResearchAndMarkets.com‘s offering. The enzymatic DNA synthesis market value is projected to reach US$ 2,244.88 million by…
Gold Medal flour officially linked to Salmonella outbreak stretching from coast to coast
The Food and Drug Administration has officially linked a Salmonella Infantis outbreak to Gold Medal flour produced by General Mills. The company recalled certain flour products on April 28 because of Salmonella Infantis contamination, but did not mention the outbreak in its recall notice. The company did not report how…
CDC eases COVID vaccination rule on international travelers as expiration looms
The Centers for Disease Control and Prevention moved Thursday to formally loosen its COVID-19 vaccination requirement on foreign visitors, which will now allow some to board flights into the U.S. with only a single dose of a COVID-19 vaccine from Pfizer or Moderna. “Because some traveler vaccine records might not…
Helix is Weaving Population Genomics into the Healthcare Fabric
James Lu, MD, PhD, has been interested in the intersection of clinical care and genomics since the early days of next-generation sequencing (NGS) and the dawn of personal genomics in the mid-to-late 2000s. “In the early days of NGS, a lot of the early problems in that space, before Illumina…
Alternative CDC20 translational isoforms tune mitotic arrest duration
Musacchio, A. The molecular biology of spindle assembly checkpoint signaling dynamics. Curr. Biol. 25, R1002–R1018 (2015). Article CAS PubMed Google Scholar Lara-Gonzalez, P., Pines, J. & Desai, A. Spindle assembly checkpoint activation and silencing at kinetochores. Semin. Cell Dev. Biol. 117, 86–98 (2021). Article CAS PubMed PubMed Central Google Scholar …
Playing pickleball helps older adults to reach the recommended dose of physical activity
Pickleball isn’t just fun and easy to play – it’s also potentially heart healthy. Playing pickleball helped a small group of adults aged 65 years and older reach their recommend weekly dose of moderate to vigorous physical activity, according to a pilot study by North Carolina State University researchers. “We…
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity
Agency for Toxic Substances and Disease Registry (ATSDR) (2001) Toxicological profile for Benzidine. Update. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service. www.atsdr.cdc.gov/toxprofiles/tp62.pdf. Accessed 19 Jan 2023 Agnello M, Fontana M (2015) Survey on European studies of the chemical characterisation of tattoo ink products and the…
The enzymatic DNA synthesis market value is projected to
New York, April 25, 2023 (GLOBE NEWSWIRE) — Reportlinker.com announces the release of the report “Enzymatic DNA Synthesis Market Forecast to 2028 – COVID-19 Impact and Global Analysis By Product Type, Application, End User, and Technology” – www.reportlinker.com/p06452105/?utm_source=GNW Surging Number of Product Launches Drives Growth of Enzymatic DNA Synthesis Market…
Bluebird Submits BLA for Sickle-Cell Disease Gene Therapy
Pictured: Illustration showing blood vessel with normal and sickled red blood cells / Adobe, tussik bluebird bio announced Monday that it has submitted a Biologics License Application (BLA) for lovotibeglogene autotemcel (lovo-cel), a gene therapy treatment for sickle cell disease (SCD). Bluebird is seeking approval to sell lovo-cel as a…
Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine
Centers for Disease Control and Prevention. Past Seasons Vaccine Effectiveness Estimates, www.cdc.gov/flu/vaccines-work/past-seasons-estimates.html (2022). Accessed 10 March 2022. Centers for Disease Control and Prevention. Pandemic influenza—past pandemics, www.cdc.gov/flu/pandemic-resources/basics/past-pandemics.html (2022). Accessed 10 March 2022. Erbelding, E. J. et al. A universal influenza vaccine: the strategic plan for the National Institute of Allergy…
Screening of natural Wolbachia infection in mosquitoes (Diptera: Culicidae) from the Cape Verde islands | Parasites & Vectors
Study area and sample collection An entomological survey was carried out in Cape Verde between February and June 2021. Larval and adult mosquito samples were collected on six islands (Santiago, Brava, Fogo, Maio, Santo Antão, and Boavista; Fig. 1) using BG-Sentinel and Centers for Disease Control and Prevention (CDC) light traps,…
3D-printed microneedle patch could make painless ‘on-demand’ vaccines a reality
CAMBRIDGE, Mass. — Scientists have developed a 3D-printed microneedle vaccine patch patients can apply to their skin, offering a pain-free alternative to traditional injections. Researchers from the Massachusetts Institute of Technology (MIT) say you can store these patches at room temperature for months, making them ideal for large-scale shipments to…
Solved i need help with Q5 and Q6. data: These data come
i need help with Q5 and Q6. data: These data come from www.kaggle.com/cdc/behavioral-risk-factor-surveillance-system Predict the number of days in the past 30 days that mental health was not good from marital status. Your output should match the value included in the summary below. This value is given to you as…
How Whole Exome Sequencing Improves Identification of People With Cancer Predisposition Syndromes
Among individuals who consented to whole-exome sequencing (WES) and were identified as carriers of predisposition genes for hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (also known as hereditary nonpolyposis colorectal cancer or HNPCC), 39.2% would not have qualified for genetic screening under current guidelines. This conclusion is based…
Top 10 CRISPR Stocks To Buy
In this article, we discuss the top 10 CRISPR stocks to buy. If you want to see more stocks in this selection, check out Top 5 CRISPR Stocks To Buy. Molecular biology, genetics, and genomics are in a significant period in history where technical capabilities and methods enable the editing…
Exploiting C. diff’s Molecular ‘Superpower’
Credit: CDC Key points: A new study shows how two molecular mechanisms work together to make C.diff “extra resistant.” The researchers discovered a novel protein that conveys resistance to a specific class of antibiotics that seems to worsen C.diff infections. With its affinity for rapidly spreading through healthcare settings, increasing…
Association of 410L, 1016I and 1534C kdr mutations with pyrethroid resistance in Aedes aegypti from Ouagadougou, Burkina Faso, and development of a one-step multiplex PCR method for the simultaneous detection of 1534C and 1016I kdr mutations | Parasites & Vectors
Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, et al. The global distribution and burden of dengue. Nature. 2013;496:504–7. doi.org/10.1038/nature12060. Article CAS PubMed PubMed Central Google Scholar WHO. WHO | Dengue Fever – Burkina Faso. World Health Organization 2017 www.who.int/emergencies/disease-outbreak-news/item/6-november-2017-dengue-burkina-faso-en; 2017. Tarnagda Z, Cissé A, Bicaba…
Study Shows Feasibility of Using Exome Sequencing to Conduct CDCT1 Genetic Condition Screening
Image Credit: © MicroOne [stock.adobe.com] Whole exome sequencing has been deemed a potential method to help execute CDCT1 genetic condition screening on large populations, according to study findings presented during the American Association for Cancer Research (AACR) Annual Meeting 2023. The findings, which were presented by Niloy (Jewel) Samadder, MD,…
Genomics Market to Reach $94.86 Billion by 2030 at CAGR 16.5%: Grand View Research, Inc.
SAN FRANCISCO, April 19, 2023 /PRNewswire/ — The global genomics market size is expected to reach USD 94.86 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to register a CAGR of 16.5% in the forecast period owing to the increasing demand…
CDCT1 Testing Study Highlights Pitfalls in Current NCCN Genetic Condition Screening Guidelines
Niloy (Jewel) Samadder, MD Whole exome sequencing testing identified genetic conditions in individuals who ordinarily would not have met current National Comprehensive Cancer Network (NCCN) guidelines for testing, according to data presented during the 2023 AACR Annual Meeting. The findings, which were presented by Niloy (Jewel) Samadder, MD, demonstrated that…
Results from Astellas’ Phase 3 SPOTLIGHT Trial of Investigational Zolbetuximab Published in The Lancet
TOKYO, April 14, 2023 /PRNewswire/ — Astellas Pharma Inc. (TSE: 4503, President and CEO: Naoki Okamura, “Astellas”) today announced that The Lancet published detailed data from the Phase 3 SPOTLIGHT trial evaluating first-line treatment with zolbetuximab, an investigational first-in-class Claudin 18.2 (CLDN18.2) targeted monoclonal antibody, plus mFOLFOX6 (a combination regimen…
Can New Technology Detect Cancer Sooner?
Credit : BlackJack3D / iStock / Getty Images Plus Decades ago, the oncology community took on the crucial challenge of detecting cancer at the earliest possible stage. Overall, survival rates improve dramatically for cancers detected before metastasis. For example, the U.S. Centers for Disease Control and Prevention (CDC) notes that…
4 US-Approved Vaccines Do Not Contain These Substances
The United States has only approved and authorized four COVID-19 vaccines amid the pandemic. All of them are deemed safe because they do not contain toxic and unhealthy components, as well as substances that affect or interact with DNA. The four vaccines approved for use in the U.S. are the…
What to Know About Hard Tick Relapsing Fever, a New Disease in California
A man in California had recurrent fevers that came and went during a three-month period. He had the state’s first documented infection with the tick-borne bacteria Borrelia miyamotoi. These infections may become more common as people spend time outside and diagnostics improve. Loading Something is loading. Thanks for signing up!…
Chinese scientists working on COVID-19 origins-tracing discuss latest findings, address data transparency controversy
coronavirus Photo:VCG Editor note: Amid waves of heated discussion about the origins of COVID-19 in the international community and China’s recent release of new analysis collected at Wuhan’s Huanan Seafood Market, the Global Times reporters on Friday conducted an interview with Liu Jun, a researcher from the China CDC who…
China releases data showing raccoon dog DNA in Wuhan market
Chinese government scientists released a much-anticipated study of a market in the city of Wuhan on Wednesday, acknowledging that animals susceptible to the coronavirus were present at the time the virus appeared. – Advertisement – But the scientists also said it was stationary without being clear how the pandemic started…
China publishes data showing raccoon dog DNA in Wuhan market
Chinese government scientists released a long-awaited study on Wednesday of a market in the city of Wuhan, acknowledging that animals susceptible to the coronavirus were there at the time the virus emerged. But the scientists also said it remained unclear how the pandemic started. Fritzi the raccoon plays with water…
Is whole genome sequencing the gold standard for TB testing?, ET HealthWorld
By Ritika Sakhuja New Delhi: Tuberculosis, a bacterium infection that affects the lungs is a major public health problem in India, with an estimated 21.4 lakhs TB cases reported in 2021, 18 per cent higher than in 2020, as per the World Health Organisation (WHO). However, pulmonary TB (PTB), a…
Phylogenomic analysis uncovers a 9-year variati…
Your new post is loading… Your new post is loading… Scooped by Ed Rybicki Scoop.it! Scooped by Ed Rybicki Scoop.it! This study has helped elucidate the responses underlying susceptibility to H5N1 influenza in avian species, which will be critical in developing sustainable strategies for future control of HPAI in domestic…
Lyra: Negative EV With A Very Compelling Treatment For Chronic Rhinosinusitis In Phase 3
Pornpak Khunatorn Lyra Therapeutics – Overview Lyra Therapeutics (NASDAQ:LYRA) (the Company), a Massachusetts drug/device combination company trading on the NASDAQ, is developed two forms of a proprietary elastomeric drug-eluting matrix for chronic rhinosinusitis (CRS) patients who fail normal medical management of their condition. The Company’s product can be inserted into…
Expanding whole genome sequencing capacity in the Asia-Pacific Region
The Centre for Pathogen Genomics (The Centre), in partnership with the Association of Public Health Laboratories (APHL) and the U.S. Centers for Disease Control and Prevention (U.S. CDC), recently hosted a week of training for Illumina Whole Genome Sequencing (WGS) at the Peter Doherty Institute for Infection and Immunity (Doherty…
Beethoven’s DNA Shows Hepatitis B Infection, Liver Disease
DNA pulled from strands of Ludwig van Beethoven’s hair suggests that the German composer had health problems associated with his liver that likely led to his death at age 56 nearly 200 years ago. A study published in Current Biology found that Beethoven had a genetic risk for liver failure,…
Phylogenomic analysis uncovers a 9-year variation of Uganda influenza type-A strains from the WHO-recommended vaccines and other Africa strains
Demographic characteristics of sampled patients The Uganda Virus Research Institute National Influenza Centre (UVRI-NIC) laboratory tested 18,353 patients between 22nd October 2010 and 9th May 2018. Thirteen-percent (2404/18,353) were positive for influenza, 69.88% (1680/2404), 29.62% (712/2404), and 0.17% (4/2404) had influenza A, B, and A/B co-infection, respectively (Fig. 1A). IAV positives…
NCBI Datasets Virus Data Package
Sequences and metadata for a set of virus GenBank genomes or SARS-CoV-2 proteins The NCBI Datasets Virus Data Package contains sequences and metadata for a set of requested virus GenBank genomes or SARS-CoV-2 proteins. The data package may include genome, coding sequence (CDS) and protein sequences in FASTA format, and…
BIO-Europe Spring 2023: The Highlights
BIO-Europe Spring is one of Europe’s biggest biotech partnering events with discussion topics ranging from platform technologies and manufacturing to biotech investments. Here are some of the key take-home reports from the proceedings. The event, which took place from March 20 to 22, in the budding biotech hub of Basel,…
Chinese Officials Release ‘Updated Analysis’ of 1,300 Samples From Wuhan Market
“Chinese officials have released an updated analysis of more than 1,300 samples taken from the Wuhan wet market at the beginning of the Covid-19 pandemic,” reports the Telegraph: In a preprint published on Wednesday, researchers from the Chinese Center for Disease Control and Prevention said there was “convincing evidence” that…
FDA announces new Salmonella outbreak; other investigations continue
Federal officials have discovered a new outbreak of infections caused by Salmonella Infantis. Investigators with the Food and Drug Administration have not yet determined what food or beverage is the source of the Salmonella. A dozen people have been confirmed sick, but the FDA has not reported their ages or…
Klebsiella quasipneumoniae in intestine damages bile acid metabolism in hematopoietic stem cell transplantation patients with bloodstream infection | Journal of Translational Medicine
Almyroudis NG, Fuller A, Jakubowski A, Sepkowitz K, Jaffe D, Small TN, et al. Pre- and post-engraftment bloodstream infection rates and associated mortality in allogeneic hematopoietic stem cell transplant recipients. Transpl Infect Dis. 2005;7(1):11–7. Article CAS PubMed Google Scholar Auletta JJ. Current uses and outcomes of hematopoietic cell transplantation (HCT):…
Beethoven’s DNA reveals clues about his health, death and infidelity in family
An international team of researchers have used five matching locks of hair from celebrated composer Ludwig Van Beethoven to sequence his genome for the first time. While doing so, they have discovered clues about his health and also questions about whether there was an “extra-pair paternity event” in his family…
SARS-Cov-2 Metagenomics Data From China CDC On GISAID
(MENAFN– Caribbean News Global) SAGO statement GENEVA, Switzerland – On 12 March 2023, World Health Organization (WHO) was made aware of new SARS-CoV-2 sequences and metagenomics data associated with samples collected in the Huanan Seafood Wholesale Market, Wuhan, China, from January 2020, that became available on GISAID for a short…
Here’s the full analysis of newly uncovered genetic data on COVID’s origins
Enlarge / Security guards stand in front of the closed Huanan Seafood Wholesale Market in the city of Wuhan, in the Hubei Province, on January 11, 2020, where the Wuhan health commission said that the man who died from a respiratory illness had purchased goods. A group of independent international…
Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine
Harden, V. A. Rocky mountain spotted fever: History of a twentieth-century disease Vol. 16 (Johns Hopkins University Press, 1990). Google Scholar Maxey, E. E. M., G T; Leary, J W. (1899) Some observations on the so-called spotted fever of Idaho. Med Sentinel, 7: 433–438. Dantas-Torres, F. Rocky mountain spotted fever….
Non-Existent Vaccine Microchips Could Soon Be Banned in Missouri
Stock photo of a microchip in a syringe Missouri state legislators are trying to regulate the fabricated scene inside this stock photo. A subset of Missouri legislators care deeply about freedom. For instance: The God-given right to NOT accept a life-saving vaccination and still attend public school or go to…
Campbell Neurosciences creates saliva test for suicidal thoughts
Therapeutic Solutions International (TSOI) has announced that its spin-off biotech company, Campbell Neurosciences, Inc., obtained successful validation of its suicidal ideation predictive test using a saliva-based system. Previously, the company reported successful stratification of suicidal tendencies using a proprietary blood-based biomarker. In the trial, the company previously assessed levels of…
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms
Knockdown of LFPRLR reduces splenic B-cell subsets in SLE-prone mice To investigate whether the PRL-LFPRLR axis raises the risk of initiation of B-cell malignancies, we compared SLE-prone MRL-lpr mice treated with either control SMO or LFPRLR SMO. Among SLE-prone models, we chose MRL-lpr mice because they accumulate genetic lesions indicative…
Raccoon dogs at Wuhan market linked to COVID origins in new study
Raccoon dogs have been linked to the origins of COVID in a new study suggesting the pandemic may have emanated from animals and not a laboratory leak. International scientists identified the dogs’ DNA mixed with the virus from genetic material collected at a market near where the first human cases were…
PainReform Announces Commencement of Phase 3 Clinical
TEL AVIV, Israel, March 14, 2023 (GLOBE NEWSWIRE) — PainReform Ltd. (Nasdaq: PRFX) (“PainReform” or the “Company”), a clinical-stage specialty pharmaceutical company focused on the reformulation of established therapeutics, today announced that it has commenced a Phase 3 clinical trial of PRF-110, the Company’s lead drug candidate, targeting the post-operative…
Biologist Bioinformatics Direct Hire Job in ATLANTA, GA
Summary As a global leader in public health & health promotion, CDC is the agency Americans trust with their lives. In addition to our everyday work, each CDC employee has a role in supporting public health emergency management, whether through temporary assignments to emergency responses or sustaining other CDC programs…
Breast Implant Illness: Symptoms, Diagnosis, Treatment
Breast implant illness (BII) is a group of symptoms that can occur after implant insertion. Though this terminology applies to this group of symptoms, it is not an official medical diagnosis. Symptoms of breast implant illness include fatigue, brain fog, joint pain, and more. BII symptoms can affect anyone regardless of…
TOPCODING IN RSTUDIO – Stack Overflow
TOPCODING IN RSTUDIO – Stack Overflow …