Tag: CDC

Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development. The method was tested to produce a weakened or “attenuated” version of a mouse cytomegalovirus, a common…

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“DNA Virus Vaccine” Created To Fight DNA Viruses

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.   The method was tested to produce a weakened or “attenuated” version of a mouse cytomegalovirus, a…

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Rutgers scientists produce “DNA virus vaccine

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.   The method was tested to produce a weakened or “attenuated” version of a mouse cytomegalovirus, a…

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Novavax vaccine for COVID-19 | Waushara Argus

Currently, according to the CDC, there are three main types of COVID-19 vaccines that are approved or authorized for use in the United States: mRNA, viral vector, and protein subunit. Each type of vaccine prompts our bodies to recognize and help protect us from the virus that causes COVID-19. None…

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A potent, broadly protective vaccine against SARS-CoV-2 variants of concern

Cells and viruses hACE2 expressing BHK-21 (BHK-21-hACE2) and Vero-E6 cells were provided by State Key Laboratory of Virology, Wuhan University. Vero-E6 cells were cultured in DMEM (Gibco, Cat.11995–040) supplemented with 10% fetal bovine serum (Gibco, Cat.10091–148) and 1% penicillin and streptomycin solution (BasalMedia, Cat.S110JV) at 37°C with 5% CO2. BHK-21-hACE2…

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The Next Generation of COVID-19 Vaccines and Boosters

The US Food and Drug Administration (FDA) emergency use authorization (EUA) for the first vaccines combating COVID-19 was a milestone in the 2020 pandemic. Due to this provision, Pfizer-BioNTech’s BNT162b2 (Comirnaty), Moderna’s mRNA-1273 (Spikevax), and Johnson & Johnson/Janssen’s COVID-19 vaccine (Ad26.COV2.S) received EUAs for COVID-19 prevention in December 2020, February…

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Cellular glycan modification by B3GAT1 broadly restricts influenza virus infection

Ethics statement All procedures involving laboratory mice were approved by the Duke University IACUC under the protocol numbers A189-18-08 and A142-21-07. Mice were housed with up to five mice per cage and the ambient room conditions ranged from 70–74 °F and 30–70% humidity with a 12-hour dark/light cycle. Animals were assessed…

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Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine

Animals and immunizations The study protocol and all veterinarian procedures were approved by the Bioqual IACUC per a memorandum of understanding with the Duke IACUC, and were performed based on standard operating procedures. Macaques studied were housed and maintained in an Association for Assessment and Accreditation of Laboratory Animal Care-accredited…

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[PATCH 07/14] iio: st_sensors: core and lsm9ds0 switch to devm_regulator_bulk_get_enable()

[PATCH 07/14] iio: st_sensors: core and lsm9ds0 switch to devm_regulator_bulk_get_enable() – Jonathan Cameron From: Jonathan Cameron <jic23@kernel.org> To: linux-iio@vger.kernel.org Cc: Matti Vaittinen <mazziesaccount@gmail.com>, Matti Vaittinen <matti.vaittinen@fi.rohmeurope.com>, Cosmin Tanislav <cosmin.tanislav@analog.com>, Jagath Jog J <jagathjog1996@gmail.com>, Sean Nyekjaer <sean@geanix.com>, Dmitry Rokosov <DDRokosov@sberdevices.ru>, Linus Walleij <linus.walleij@linaro.org>, Andy Shevchenko <andriy.shevchenko@linux.intel.com>, Michael Hennerich <michael.hennerich@analog.com>, Lorenzo Bianconi…

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Bioinformatics Analyst I (Partial Telework) (Sign-On Bonus) job with University of Maryland Baltimore

Job Description*** Partial telework allowed in MD or contiguous states*** The University of Maryland, Baltimore (UMB) School of Medicine is now hiring a Bioinformatics Analyst I (BAI) to join the Institute for Genome Sciences, for our Human Disease Ontology Knowledgebase (DO-KB) team. We are looking for an experienced and motivated…

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Editas Medicine: Clinical Hold Lifted; Management Upbeat (NASDAQ:EDIT)

gorodenkoff/iStock via Getty Images The discovery of the CRISPR gene-editing tool has helped medical companies develop immunological defenses and curative systems against pathogens. Notable companies using this technology include CRISPR Therapeutics (CRSP), Intellia Therapeutics (NTLA), and Editas Medicine (NASDAQ:EDIT). Editas has an expansive pipeline under research. It includes Vivo gene-edited…

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Research Faculty- Department of Biostatistics and Bioinformatics in UNAVAILABLE, for Emory Healthcare

Details Posted: 24-Jun-22 Location: UNAVAILABLE, Salary: Open Categories: Physicians/Surgeons Discover Your Career at Emory University Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribute to the diversity and excellence of…

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Evaluation of Acute Adverse Events after Covid-19 Vaccination during Pregnancy

To the Editor: Pregnant women with symptomatic coronavirus disease 2019 (Covid-19) have a higher risk of adverse outcomes than do women who are not pregnant.1,2 In part because of these findings, Covid-19 vaccination has been recommended for pregnant women. However, uptake has been lower in pregnant women than among women…

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Binding of the HSF-1 DNA-binding domain to multimeric C. elegans consensus HSEs is guided by cooperative interactions

The heat-shock response is represented by a small set of genes in C. elegans We initially aimed at identifying those HSE-containing promoters that are most strongly upregulated under heat-stress conditions. Given that the HSR is complex in nematodes we used data from several heat-shock studies based on microarray and RNAseq…

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How immunisation plays a key role in disease prevention

We should know by now that a simple viral disease can quickly spiral into a full-blown global pandemic that can easily bring the world to its knees. Immunisation has prevented more than 13 million deaths of children in the last two decades through UNICEF’s efforts.  In the US alone, approximately…

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Bispecific antibodies | Scientist Live

Bispecific antibodies: rising stars in antibody therapeutics Monoclonal antibodies (mAbs) are important therapeutic agents for the treatment of many human diseases, such as cancer, autoimmune diseases, cardiovascular diseases, asthma, and viral infections. Unlike monospecific mAbs, bispecific antibodies (bsAbs) are antibodies containing two antigen-binding sites and therefore can simultaneously target two…

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Mass Vaccination Triggers Spike in Cases, Deaths

Researchers have confirmed that it’s not the SARS-CoV-2 virus itself damaging the body’s cells, it’s the spike protein. And it does this by binding ACE2, which can lead to mitochondrial damage. STORY AT-A-GLANCE Doctors for COVID Ethics have been warning about the potential for gene-based COVID-19 “vaccines” to cause blood…

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Mbedtls Application On Tcp

How to use mbedTLS library in Keil or IAR IDEs? I want to do an RSA encryption/decryption using my AT91SAM7S256 ARM MCU.After googling I found mbed TLS library. The IP networking interface includes TLSSockets which behave similarly to normal TCP sockets but automatically use Mbed TLS to set up a…

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Local Doctors Compare Vaccine Types and COVID-19 Strategies While China Struggles to Limit Omicron Rise

MADISON (WKOW) The Wisconsin Department of Health Services said the BA2 Omicron sub-variant is now responsible for the majority of new COVID-19 cases in the United States. The number of cases is slowly increasing, but we have not seen a major increase in the US since January. China’s largest city,…

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Get Politics Out of Health Care

Medical freedom is a right that must be protected for all; it transcends politics and applies to people regardless of political party. Speaking with The New American at the Conservative Political Action Committee (CPAC) conference in Orlando, Florida, Dr. Robert Malone, the inventor of the mRNA and DNA vaccine core…

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Chief of Bioinformatics | ID/HIV Career Center

Business Title Chief, Bioinformatics, Public Health Laboratory Civil Service Title CITY RESEARCH SCIENTIST Title Classification Non-Competitive Proposed Salary Range $ 96,772.00 – $140,660.00 (Annual) Work Location 455 First Ave., N.Y. Division/Work Unit PHL Admin & Lab Support As of August 2, 2021, all new hires must be vaccinated against the…

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Placenta has clues for an early diagnosis of ASD

The researchers of the‘UC Davis MIND during their research they used the genomic sequencing to find a DNA methylation signature in the placenta of infants diagnosed with autism. This hallmark has been linked to early fetal neurodevelopment. Thanks to this study, a new human gene linked to fetal brain development…

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Nuprobe USA Inc. Quality Assurance Manager

Quality Assurance Manager- Molecular NGS, PCR, IVD Quality Assurance ManagerHouston TX NuProbe USA Inc. is looking for a Quality Assurance Manager to lead the Quality program to establish and maintain compliance to ISO: 9001, ISO: 13485, and FDA 21 CFR Part 820 Quality System Regulations. NuProbe USA is a rapidly…

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Cell Strain-Derived Induced Pluripotent Stem Cells as an Isogenic Approach To Investigate Age-Related Host Response to Flaviviral Infection

INTRODUCTION Dengue is the most common mosquito-borne viral disease globally (1). This acute disease, which can be life-threatening, is caused by four different dengue viruses (DENVs) (DENV-1, DENV-2, DENV-3, and DENV-4). An estimated 390 million people are infected with these DENVs annually (2), and populations throughout the tropics face frequent…

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Manufacturing Associate Job Opening in Houston, TX at Nuprobe USA Inc.

MANUFACTURING ASSOCIATE (T1 or T2) NuProbe USA is hiring one Manufacturing Associate (T1 or T2) for its Houston (TX) location. The successful candidate will have the opportunity to join the NuProbe family in the Manufacturing Department reporting directly to the Manufacturing Manager. PRIMARY PURPOSE OF POSITION The new hire will…

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In-Depth Analysis of Bacillus anthracis 16S rRNA Genes and Transcripts Reveals Intra- and Intergenomic Diversity and Facilitates Anthrax Detection

Various ratios of 16S-BA/BC-alleles constitute possible explanations for differences in FISH signals of cells of diverse B. anthracis strains (Fig. 1). Indeed, we found a significant correlation between 16S-BA/BC-allele ratios in sequenced genomes and mean intensities of the Cy3 FISH signals targeting the16S-BA-allele (tested with the cor.test function in R, Pearson’s…

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Zachary Piper Solutions hiring 100% Remote Senior Bioinformatician in United States

Job DescriptionZachary Piper Solutions is looking for a Senior Bioinformatician supporting the Centers for Disease Control and Prevention (CDC). The ideal candidate would prepare for, prevent, and respond to infectious diseases, including outbreaks, bioterrorism, and other public health emergencies. Responsibilities: Experience with genomic epidemiology, genomic sequencing, identifying pathogen clusters and…

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The Identification of Prognostic and Metastatic Alternative Splicing in Skin Cutaneous Melanoma

Skin cutaneous melanoma (SKCM) is a type of highly invasive cancer originated from melanocytes. It is reported that aberrant alternative splicing (AS) plays an important role in the neoplasia and metastasis of many types of cancer. Therefore, we investigated whether ASEs of pre-RNA have such an influence on the prognosis…

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A genomic mutation spectrum of collecting duct carcinoma in the Chinese population

This article was originally published here BMC Med Genomics. 2022 Jan 3;15(1):1. doi: 10.1186/s12920-021-01143-2. ABSTRACT BACKGROUND: Renal collecting duct carcinoma (CDC) is a rare and lethal subtype of renal cell carcinoma (RCC). The genomic profile of the Chinese population with CDC remains unclear. In addition, clinical treatments are contradictory. In…

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Salmonella outbreak detected in half of US states

The Centers for Disease Control and Prevention (CDC) warned Friday that an outbreak of salmonella due to an “unknown food source” has been detected in 25 states across the U.S. The agency said that on Sept. 2, it identified an outbreak of 20 salmonella oranienburg infections and that, since then,…

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Technology to the Rescue. How Genome Sequencing Helps Save Lives | by Washington State Department of Health | Public Health Connection | Sep, 2021

How Genome Sequencing Helps Save Lives COVID-19 cases reached high levels, and variants of the virus, like delta, are even more contagious than the original strain. So how exactly are we tracking this? For many years, Washington state has used a technology called genome sequencing. Genome sequencing is basically a…

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Mystery Salmonella Outbreak Strikes 127 People From 25 States, CDC Still Investigating Potential Source

The Centers for Disease Control and Prevention (CDC) has once again identified a multi-state Salmonella outbreak in the country this year. The last reported disease outbreak was caused by Salmonella typhimurium and Salmonella infantis identified in Italian deli meats, such as salami, and prosciutto. The Denver Channel reported that the recent Salmonella outbreak…

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Zika Vax in the Works; STI Guidelines Updated

TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center in El Paso, look at the top medical stories of the week. This week’s topics include screening…

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Mystery Salmonella Oranienburg Outbreak strikes 127 in 25 states

Likely linked to restaurant exposures – Texas hardest hit. On September 2, 2021, CDC identified an outbreak of 20 Salmonella Oranienburg infections. Since then, the outbreak has grown rapidly. As of September 15, 2021, 127 people infected with the outbreak strain of Salmonella Oranienburg have been reported from 25 states….

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The 13 health care leaders on the list

Time this week released its “100 Most Influential People” list, which includes a number of individuals who have made major contributions to health care. The 10 ‘most influential’ health care companies, according to TIME The list This year, TIME recognized several health care providers, scientists, public health officials, and advocates for their…

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Researchers identify 28 new foods associated with disease outbreaks

September 17, 2021 2 min read Source/Disclosures Published by: Disclosures: The authors report no relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email…

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Dr. J. Curtis Nickel Urinary Microbiome Study Using MicroGenDX NGS Indicates Microbial Diversity Varies by Age and Gender | News

ORLANDO, Fla., Sept. 14, 2021 /PRNewswire-PRWeb/ — A study to help understand the implications of Next-Generation DNA Sequencing (NGS) in the diagnosis and treatment of Urinary Tract Infections (UTIs) and other inflammatory urological conditions has been completed, and results were presented at the September, 2021 AUA Conference. The study, a collaboration…

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Dr. J. Curtis Nickel Urinary Microbiome Study Using MicroGenDX NGS Indicates Microbial Diversity Varies by Age and Gender

MicroGenDX Logo The study, a collaboration between Dr. J. Curtis Nickel and MicroGen Diagnostics, identified some 643 microbial species among 211 healthy subjects (106 female and 105 male) using NGS, with significant differences in microbial diversity based on gender, age, and previous antibiotic use. ORLANDO, Fla. (PRWEB) September 14,…

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Genomic and phenotypic characteristics for Vibrio vulnificus

Background Fisheries and aquaculture are becoming increasingly intensive to meet recent human consumption, resulting in proliferation of marine pathogens and food security concerns.1,2 Vibrio species, as one of the most dangerous foodborne pathogens, cause vibriosis in human around the world.3 It has been reported that vibriosis resulted in 80,000 illnesses…

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foursquare dataset kaggle

Using the Foursquare API and querying for the above venues, the best locations can be shortlisted. Python, Foursquare API Location Data, Kaggle Data, Web Scraping, KMeans Clustering, Pandas, Sci-kit Learn See project. Data came from Kaggle Dataset , and it contains a few million Amazon customer reviews. I will be…

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The challenge of finding new tools to fight prostate cancer

Aurich Lawson | Getty Images In the US, September is National Prostate Cancer Awareness Month. This feature highlights why catching prostate cancer early can be critical, and what researchers are doing to improve the odds of controlling the disease once it’s found. Prostate cancer is a paradox. It has one…

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Antibiotic Resistance Genes | IDR

Witawat Tunyong,1 Weewan Arsheewa,2 Sirijan Santajit,3,4 Thida Kong-ngoen,1 Pornpan Pumirat,1 Nitat Sookrung,5,6 Wanpen Chaicumpa,6 Nitaya Indrawattana1 1Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand; 2Department of Microbiology, Phrapokklao Hospital, Chanthaburi, 22000, Thailand; 3School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, 80161, Thailand;…

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Aug 21 | Technolatry ft. Marie Vaunt

Technolatry – The Fall of the HumansAdmission includes one drink ticketAccept your fate.TECHNO + DNBAbove Stage:Marie VauntBeau KellyDJ ClairityJust TreesDazzle Room:The DoctorWhisky DevilFlowerchildRomhakRaised in Japan and based in Los Angeles, Marie Vaunt burst onto the scene in March 2018 with her debut single “Witchcraft”, which skyrocketed through the Beatport Techno…

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Kenya Targets Easing Sickle Cell Disease Pain Through Quality and Affordable Care

Health experts in Kenya aim to reduce the number of children born with sickle cell disease — an inherited blood disorder — by more than 12 times through public education and awareness, as the country premiered a guideline for controlling and managing the disease. The guideline titled Sickle Cell Disease…

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