Tag: cRNA

CAR links hypoxia signaling to improved survival after myocardial infarction

Experimental design The objective of this study was to test the hypothesis that CAR can improve cardiac function after MI by containing the lesion and improving remodeling. We used an in vivo loss-of-function approach with coronary artery ligation in inducible heart-specific CAR knockout mice. In a complementary gain-of-function approach, we…

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Comprehensive Analysis of circRNA Expression Profiles in Human Brown Adipose Tissue

Introduction The excessive accumulation of adipose tissue is one of the leading factors of obesity.Citation1,Citation2 Adipose tissues are typed as white adipose tissue (WAT), brown adipose tissue (BAT) and beige adipose tissue.Citation3 The primary function of WAT is storing triglyceride, while BAT, in contrast to WAT, dissipates the energy of…

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The CRISPR/Cas9 syst…

The CRISPR/Cas9 system is made of Cas9 nuclease and single-guide RNA (sgRNA). The sgRNA is an engineered single RNA molecule containing crispr RNA and tracr RNA parts. The sgRNA recognizes the target sequence by standard Watson-Crick base pairing. It has to be followed by a DNA motif called a protospacer…

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You Have 3 Chances To Interview For CRNA Then You Can No Longer Apply Rule With RRNA Ivan

Did you know that you only have three chances to interview for a CRNA school before you can no longer apply there? This interview limit was news to Ivan, but that didn’t stop him from giving up. He applied for a CRNA school in 2019, but his application went missing….

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