Tag: CSI

acCRISPR: an activity-correction method for improving the accuracy of CRISPR screens

acCRISPR framework acCRISPR performs essential gene identification by calculating two scores for each sgRNA, namely the cutting score (CS) and the fitness score (FS). CS and FS are the log2-fold change of sgRNA abundance in the appropriate treatment sample with respect to that in the corresponding control sample (see Supplementary…

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[slurm-users] Reservation with REPLACE_DOWN flag not replacing down nodes

I have this reservation which has the REPLACE_DOWN flag set: ReservationName=test StartTime=2020-12-14T09:00:00 EndTime=2023-12-14T09:00:00 Duration=1095-00:00:00    Nodes=traverse-k05g4 NodeCnt=1 CoreCnt=32 Features=(null) PartitionName=all Flags=IGNORE_JOBS,WEEKDAY,SPEC_NODES,REPLACE_DOWN,NO_HOLD_JOBS_AFTER_END    TRES=cpu=128    Users=(null) Groups=(null) Accounts=pppl,csi,pu,tromp,cses Licenses=(null) State=ACTIVE BurstBuffer=(null) Watts=n/a    MaxStartDelay=(null) Unfortunately, the one node in that reservation is down, and the reservation isn’t being moved to…

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Research Fellow (Cancer Science Institute of Singapore) 1 job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description A postdoctoral position is available immediately for an extremely motivated Ph.D with a strong background in molecular or cellular biology, biochemistry, or other related fields. The successful candidate will help design and conduct experiments, analyse data, write papers and grants. Projects involve studying the novel mechanisms of replication…

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Potential targets against natural killer/T-cell lymphoma found

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has discovered that a transcription factor, TOX2, was aberrantly increased in patients with natural killer/T-cell lymphoma (NKTL).  The increased TOX2 level leads to the growth and spread of NKTL, as…

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htslib-1.15.1-2.fc38 – Fedora Packages

htslib-1.15.1-2.fc38 – Fedora Packages ↵ Return to the main page of htslibView buildSearch for updates Package Info (Data from x86_64 build) Changelog Dependencies Provides Files Changelog Date Author Change 2023-01-19 Fedora Release Engineering <releng at fedoraproject dot org> – 1.15.1-2 – Rebuilt for fedoraproject.org/wiki/Fedora_38_Mass_Rebuild 2022-08-15 John Marshall <jmarshall at hey…

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Automating CRISPR-based cell line development

The growing demand for more rapid high-throughput cell-line development and improved screening in the pharmaceutical space is motivating research facilities and companies to automate their labs. Though robotics has been present in some laboratories for around four decades, it is becoming increasingly common. It helps to free researchers of repetitive…

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Research Fellow – Bioinformatician (Cancer Science Institute) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description (JR:18151) The position of Postdoctoral Fellow – with an emphasis on computational cancer genomics – is immediately available at the Cancer Science Institute of Singapore (a part of National University of Singapore). The Postdoctoral Fellow will work with the laboratories of Professor Ashok Venkitaraman, on a project studying the evolution of…

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Human DNA Is All Over The Planet, And Scientists Are Worried : ScienceAlert

Every skin flake, hair follicle, eyelash, and spit drop cast from your body contains instructions written in a chemical code, one that is unique to you. According to a new study, technology has advanced to the point that it’s now possible to sift scraps of human DNA out of the…

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Senior Research Scientist, Bioinformatician (Cancer Science Institute) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The mission of Cancer Science Institute (National University of Singapore) is to better understand the causes of human cancer across Asia, and thereby improve its detection, treatment, and prevention. Our outstanding researchers and exceptional facilities create an energetic environment for ground-breaking science and world-class training. A Senior Research Scientist position…

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Research Fellow (Cancer Science Institute of Singapore) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The mission of Cancer Science Institute (National University of Singapore) is to better understand the causes of human cancer across Asia, and thereby improve its detection, treatment, and prevention. Our outstanding researchers and exceptional facilities create an energetic environment for ground-breaking science and world-class training. The position of…

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Metagenome-based metabolic modelling predicts unique microbial interactions in deep-sea hydrothermal plume microbiomes

Design of this study In this study, we use 98 MAGs described previously from Guaymas Basin hydrothermal plumes (see Metagenomic datasets and model building in Methods) to understand metabolic interactions and evolution in hydrothermal systems (Refer Supplementary File S1 for the short name references used in this article). Both bacteria and archaea…

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Research Fellow, Bioinformatician, Cancer Science Institute, Dr Jason Pitt’s Lab job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The position of Postdoctoral Fellow with an emphasis on cancer genomics and bioinformatics is immediately available in the laboratory of Dr. Jason Pitt, which integrates data science and biological expertise to facilitate precision oncology. The Pitt Laboratory achieves this by developing cutting-edge software that allows rapid interrogation and…

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Characterization of a fold in TANGO1 evolved from SH3 domains for the export of bulky cargos

Constructs MOTH domains of human TALI (23-123), Otoraplin (18-128), and MIA (19-131), and TANGO1 (30-139) from Drosophila melanogaster (dmTANGO1(30-139)) were expressed from codon-optimized sequences in a modified pQE40 expression vector36 in M15 pRep4 E. coli strain. Human TANGO1 (21-131) (hsTANGO1 (21-131)) and TANGO1 (21-151) (hsTANGO1 (21-151)) were expressed from codon-optimized…

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JupyterHub share folder – Zero to JupyterHub on Kubernetes

Can we have share folder/volumn between pods , which are created by Jupyterhub users gcerar April 18, 2023, 9:30pm 2 Sure you can. On our setup, we have something like singleuser: … storage: capacity: 10Gi extraVolumes: – name: shm-volume emptyDir: medium: Memory – name: jupyterhub-shared persistentVolumeClaim: claimName: jupyterhub-shared-volume – name:…

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Carrier Screening Market is projected to exhibit a CAGR of 12.4% from 2023 to 2033 | Exclusive Report by FMI

The global carrier screening market is expected to record a CAGR of 12.4% between 2023 and 2033, with a size estimated in 2023 at US$ 1,343.40 million. The market’s value is expected to rise to US$ 4,323.84 million by 2033. As a result of increased funding from the public and commercial sectors…

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Wiki, Biography, Age, Family, Career, Net Worth, Boyfriend, and More

Introduction: Stacey Lauretta Dash was born in The Bronx, New York, in the United States on January 20, 1966. She is a former talk show presenter and American actress best known for co-starring Dionne Marie Davenport in the 1995 movie Clueless and the corresponding television series. _image source: theguardian.com Today…

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bam index chromosome size limit

Hello everyone, hope you are doing well SAM/BAM file format specification says that there is a limit to chromosome size that prevents indexing of .bam file, if reference genome had exceptionally large chromosomes. The limit is 2^29-1, which is around 500 M.b.p. This is quite a lot, for example, all…

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Research Assistant (Bioinformatician) (Cancer Science Institute, NUS) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The position of Research Assistant (Bioinformatician) is immediately available in the Genome and Data Analytics Core (GeDaC) at the Cancer Science Institute of Singapore (CSI) — a part of National University of Singapore. The CSI GeDaC is building a platform to facilitate the automated processing and analysis of…

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Carrier Screening Market to Reach USD 4,323.84 Million, by

NEWARK, Del, March 08, 2023 (GLOBE NEWSWIRE) — The global carrier screening market is expected to record a CAGR of 12.4% between 2023 and 2033, with a size estimated in 2023 at US$ 1,343.40 million. The market’s value is expected to rise to US$ 4,323.84 million by 2033. As a…

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Postdoctoral Fellow, Cancer Science Institute job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The Cancer Science Institute of Singapore (CSI) Career Accelerator Postdoctoral Fellowship invites outstanding applicants at the level of early-stage postdoctoral fellows. The awardees will be hosted within established research labs to develop their independent research programs and collaborate with other exceptional researchers. They will receive a competitive salary package with an…

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Alignment File Processing | Variant Analysis

Learning objectives Differentiate between query-sorted and coordinate-sorted alignment files Describe and remove duplicate reads Process a raw SAM file for input into a BAM for GATK The processing of the alignment files (SAM/BAM files) can be done either with samtools or Picard and they are for the most part interchangable….

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Research Officer, Bioinformatics job with UNIVERSITY OF MELBOURNE

Location: Parkville Role type: Full-time; Fixed-term for 1 year Faculty: Medicine, Dentistry and Health Sciences Department/School: Doherty Institute, Department of Microbiology and Immunology Salary: Level A – $97,558 – $104,717 p.a. plus 17% super The University of Melbourne would like to acknowledge and pay respect to the Traditional Owners of the lands upon which our campuses…

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Ubuntu Manpage: samtools index – indexes SAM/BAM/CRAM files

Provided by: samtools_1.10-3_amd64 NAME samtools index – indexes SAM/BAM/CRAM files SYNOPSIS samtools index [-bc] [-m INT] aln.bam|aln.cram [out.index] DESCRIPTION Index a coordinate-sorted BGZIP-compressed SAM, BAM or CRAM file for fast random access. (Note that this does not work with uncompressed SAM files.) This index is needed when region arguments are…

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DNA Evidence is Not as Reliable as Many Believe it to Be

TV-shows like CSI and Bones, have seared in the public consciousness the image of the faultless crime fighting forensic scientist and infallibility of DNA evidence.  But the reality is that DNA evidence is not what many believe it to be – it is, in fact, susceptible to human errors including…

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Investment in Advanced Technology by Leading Firms to Pump Up Future Market Expansion; Carrier Screening Market to Grow at a CAGR of 12.4% through 2033.

The global carrier screening market is expected to record a CAGR of 12.4% between 2023 and 2033, with a size estimated in 2023 at US$ 1,343.40 million. The market’s value is expected to rise to US$ 4,323.84 million by 2033. As a result of increased funding from the public and…

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Research Fellow, Bioinformatician, Cancer Science Institute, Dr Jason Pitt’s Lab 1 job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The position of Postdoctoral Fellow with an emphasis on cancer genomics and bioinformatics is immediately available in the laboratory of Dr. Jason Pitt, which integrates data science and biological expertise to facilitate precision oncology. The Pitt Laboratory achieves this by developing cutting-edge software that allows rapid interrogation and…

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Recommendations on Dynamic PersistentVolumes on Newer AWS EKS Versions – Zero to JupyterHub on Kubernetes

Hello,I’ve been walking through z2jh documentation which is thorough and great! I set up an AWS EKS cluster with eksctl. I then helm install jupyterhub-2.0.0. The newer versions of EKS tend to use the EBS CSI driver for dynamic PersistentVolume provisioning using the annotation: volume.beta.kubernetes.io/storage-provisioner: kubernetes.io/aws-ebs Your older storage documentation…

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Jupyterhub is not tracking Keycloak’s sessions – Zero to JupyterHub on Kubernetes

Hello,I have installed the Jupyterhub chart with this chart.yaml: annotations: artifacthub.io/images: | – image: jupyterhub/configurable-http-proxy:4.5.3 name: configurable-http-proxy – image: jupyterhub/k8s-hub:2.0.0 name: k8s-hub – image: jupyterhub/k8s-image-awaiter:2.0.0 name: k8s-image-awaiter – image: jupyterhub/k8s-network-tools:2.0.0 name: k8s-network-tools – image: jupyterhub/k8s-secret-sync:2.0.0 name: k8s-secret-sync – image: jupyterhub/k8s-singleuser-sample:2.0.0 name: k8s-singleuser-sample – image: k8s.gcr.io/kube-scheduler:v1.23.10 name: kube-scheduler – image: k8s.gcr.io/pause:3.8…

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10 BAM (Bioinformatics Alignment/Map) Best Practices

Bioinformatics Alignment/Map (BAM) is a powerful tool used to analyze and compare biological sequences. BAM is used to identify genetic variations, detect structural rearrangements, and compare different genomes. It is an essential tool for many areas of bioinformatics, including genomics, proteomics, and transcriptomics. In this article, we will discuss 10…

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Research Scientist, Bioinformatician, Cancer Science Institute 1 job with NATIONAL UNIVERSITY OF SINGAPORE

JOB DESCRIPTION Analyze and integrate various NGS data Build and reproduce pipelines to process all types of DNA and RNA sequencing data Maintain all source code within Git and Dockerize all pipeline components Liaise with the Scaling Unit to convert pipelines into scalable workflows To…

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Research Assistant, Bioinformatician / Cancer Science Institute, NUS job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The position of Research Assistant (Bioinformatician) is immediately available in the Genome and Data Analytics Core (GeDaC) at the Cancer Science Institute of Singapore (CSI) — a part of National University of Singapore. The CSI GeDaC is building a platform to facilitate the automated processing and analysis of…

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Did Stacey Dash bleach her skin? Here are before and after photos after what looks like skin lightening

Did Stacey Dash bleach her skin? Here are before and after photos after what looks like skin lightening Hello Everyone lastest Update about Did Stacey Dash bleach her skin? Here are before and after photos after what looks like skin lightening Welcome guys to Bulletinzone.com . Here you can Find…

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How To Install libhts-dev on Kali Linux

In this tutorial we learn how to install libhts-dev on Kali Linux. libhts-dev is development files for the HTSlib Introduction In this tutorial we learn how to install libhts-dev on Kali Linux. What is libhts-dev HTSlib is an implementation of a unified C library for accessing common file formats, such…

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Stacey Dash Bio, Age, Height, Career , Family, Salary, And Net Worth

Stacey Dash Biography Stacey Dash is a native American actress and former talk show host. In the 1995 feature picture clueless and its television series of the same name, she portrayed Dionne Marie Davenport. She appeared on television in the NBC 1982 drama pilot Farrell: For the people, that got…

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Extensively drug resistant E. coli LZ00114

Introduction Escherichia coli is a common Gram-negative opportunistic pathogen that causes invasive host infections through virulence factors such as flagella, toxin secretion, and adhesins. According to the source of the infection, pathogenic E. coli can be classified as intestinal (diarrheagenic) and extraintestinal (ExPEC). Uropathogenic E. coli (UPEC) is the most…

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File “sage/symbolic/pynac_impl.pxi”, Exception. Unhandled SIGSEGV: A segmentation fault occurred

I am not sure if this is a bug in Python or sagemath. Using sagemath 9.5 on Linux Arch. I’ll describe the problem in words, then given MWE to reproduce it. I have an integrand integrand = “F(x)*(-x^2+x)^(1/2)” as string. I pass it to a subprocess using multiprocessing. When I…

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Install pytorch in jetson nano

install pytorch in jetson nano Done! Getting Started with Jetson Nano In this tutorial, you will learn how to set up the NVIDIA ® Jetson ™ Nano and install everything you need to use the full power of the tiny embedded board. Git – Version Contol…

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Containerization: Kubernetes 1.23 stabilizes operation with two network stacks

Kubernetes 1.23 is the third and final release of container orchestration this year. Among other things, it stabilizes the dual-stack operation in the cluster, the horizontal pod autoscaler and generic ephemeral volumes. With the new functions, initially introduced as alpha, the server-side validation of fields and the connection to OpenAPI…

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Newly developed software unveils relationships between RNA modifications and cancers

In a research breakthrough, a team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has developed a software that can help reveal the relationships between RNA modifications and the development of diseases and disorders. Led by Professor Daniel Tenen and Dr…

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