Tag: diagnostic

Materials and Methods Genomic data was collected as part of the MDS National History Study or The Cancer Genome Atlas project and consented appropriately under those protocols 8 Sekeres M.A. Gore S.D. Stablein D.M. DiFronzo N. Abel G.A. DeZern A.E. Troy J.D. Rollison D.E. Thomas J.W. Waclawiw M.A. Liu J.J….

Available online 13 January 2022, 113994 doi.org/10.1016/j.bios.2022.113994Get rights and content Highlights • A one-pot CRISPR/Cas13a-based visual biosensor for the rapid and low-cost nucleic acid detection is proposed. • With a newly developed tube-in-tube vessel used in the biosensor, aerosol cross contamination could be completely avoided. • The sensor can not…

1. Nicodemus JM, Enriquez C, Marquez A, Anaya CJ, Jolivalt CG (2017) Murine model and mechanisms of treatment-induced painful diabetic neuropathy. Neuroscience 354:136–145. doi.org/10.1016/j.neuroscience.2017.04.036 CAS  Article  PubMed  Google Scholar  2. Morimoto SS, Kanellopoulos D, Manning KJ, Alexopoulos GS (2015) Diagnosis and treatment of depression and cognitive impairment in late life….

Sequence information Variant position:  322 The position of the amino-acid change on the UniProtKB canonical protein sequence. Protein sequence length:  360 The length of the canonical sequence. Location on the sequence:   IEVEQALAHPYLEQYYDPSD  E PIAEAPFKFDMELDDLPKEK The residue change on the sequence. Unless the variant is located at the beginning or at the end of…

– Fast Track Designation granted from U.S. Food and Drug Administration for PRA023 for the treatment of Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD) – – New patent granted for PRA023 companion diagnostic (CDx) reinforces Prometheus’ precision approach and extends CDx patent coverage into 2040 – – Company to present today…

Summary Background Inter-individual variability during sepsis limits appropriate triage of patients. Identifying, at first clinical presentation, gene expression signatures that predict subsequent severity will allow clinicians to identify the most at-risk groups of patients and enable appropriate antibiotic use. Methods Blood RNA-Seq and clinical data were collected from 348 patients…

This article was originally published here Int J Gen Med. 2021 Dec 29;14:10423-10428. doi: 10.2147/IJGM.S343889. eCollection 2021. ABSTRACT BACKGROUND: The role of circRNA circ_0071662 has been studied in bladder cancer. The present study aimed to analyze its involvement in esophageal squamous cell carcinoma (ESCC). METHODS: Patients with ESCC (n =…

Background: Autoantibody specificity in autoimmune diseases is variable due to each patient’s individual spectrum of autoantibodies and the inherent differences between detection methods and tests. Since false-positive results have downstream consequences, we conducted a comprehensive assessment of anti-double stranded DNA (anti-dsDNA) specificity from published studies of systemic lupus erythematosus (SLE)….

Rapid and sensitive point-of-care detection of Leptospira by RPA-CRISPR/Cas12a targeting lipL32. PLOS Neglected Tropical Diseases ( IF 4.411 ) Pub Date : 2022-01-06 , DOI: 10.1371/journal.pntd.0010112 Sirawit Jirawannaporn,Umaporn…

Added whole genome sequencing capacity enables the SOLVE-RD research program to significantly increase sample throughput MENLO PARK, Calif., Jan. 07, 2022 (GLOBE NEWSWIRE) — PacBio (Nasdaq: PACB), a leading developer of high-quality, highly accurate sequencing platforms, today announced Radboud University Medical Center (Radboudumc) in Nijmegen, the Netherlands will increase their…

The detection of viruses As shown in Table 1, viral NGS identified at least one syndrome-associated mammalian virus in 35 of 95 Kilifi County Hospital (KCH) inpatient samples (36.8%) and 23 of 95 household cohort (study investigating Who-Acquires-Infection-From-Whom, WAIFW) samples (24.2%), leading to an overall 30.5% “missed virus detection rate”….

Rare genetic disorders are caused by variants in major functional genes. Most are SNV or INDEL variants, but SVs, such as CNVs or chromosomal variants, can also be the cause. Recently, a large-scale study has also been published showing that CNVs were identified in 11-12% more infants and children with…

SOUTH SAN FRANCISCO, Calif., Jan. 07, 2022 (GLOBE NEWSWIRE) — CareDx, Inc.,  (Nasdaq: CDNA) – The Transplant Company™ focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers – today announced the results of a study led by the National Institutes of…

This article was originally published here Dev Med Child Neurol. 2022 Jan 5. doi: 10.1111/dmcn.15125. Online ahead of print. ABSTRACT AIM: To correlate clinical, radiological, and biochemical features with genetic findings in children with bilateral basal ganglia lesions of unknown aetiology, and propose a diagnostic algorithm for early recognition. METHOD:…

Summary Of Major ResponsibilitiesThe Director, Bioinformatics is self-driven, working on multiple projects that are extremely complex in scope. As a thought leader, the Director, Bioinformatics brings their knowledge and expertise to bear in planning, design, and execution to ensure successful and timely completion of large or complex projects. The Director,…

Introduction Tuberculosis (TB) is considered to be one of the top ten causes of death in the world, about a quarter of the world’s population is infected with M. tuberculosis.1 The World Health Organization (WHO) divides tuberculosis into pulmonary tuberculosis (PTB) and extra-pulmonary tuberculosis (EPTB). Although breakthroughs have been made…

doi.org/10.1038/gim.2017.56Get rights and content Abstract Purpose Invasive diagnostic prenatal testing can provide the most comprehensive information about the genetic status of a fetus. Noninvasive prenatal screening methods, especially when using cell-free DNA (cfDNA), are often limited to reporting only on trisomies 21, 18, and 13 and sex chromosome aneuploidies. This…

Introduction Sepsis is a life-threatening organ dysfunction that results from an exaggerated host immune response to disseminate infection.1 Despite improvements in treatment strategies, sepsis remains a leading cause of death in critically ill patients worldwide.2 Low platelet number, known as thrombocytopenia, is common in infectious diseases (also sometimes referred to…

NuProbe USA is seeking an experienced Sr. Manager, In-Vitro Diagnostics Operations who will be responsible for all aspects of manufacturing, including design transfer of newly developed products from research & development. The successful candidate will control production planning, scheduling and forecasting. The candidate will lead continuous improvements in manufacturing as…

Sequence information Variant position:  468 The position of the amino-acid change on the UniProtKB canonical protein sequence. Protein sequence length:  805 The length of the canonical sequence. Location on the sequence:   GTLPFTYMLEKWRWMVFKGE  I PKDQWMKKWWEMKREIVGVV The residue change on the sequence. Unless the variant is located at the beginning or at the end of…

Microbial identification of bovine milk isolates compared between conventional culture, MALDITOF and 16S rRNA 21st International Conference on Food Technology & Processing October 04-06, 2018 | London, UK David J Wilson, John R Middleton, Pamela R F Adkins and Gregory M Goodell Utah State University, USAUniversity of Missouri, USAThe Dairy…

Sequence information Variant position:  28 The position of the amino-acid change on the UniProtKB canonical protein sequence. Protein sequence length:  492 The length of the canonical sequence. Location on the sequence:   PPAIGPYYENHGYQPENPYP  A QPTVVPTVYEVHPAQYYPSP The residue change on the sequence. Unless the variant is located at the beginning or at the end of…

The Peters Lab at the La Jolla Institute for Immunology (LJI) is looking for a bioinformatics postdoc to join our efforts in profiling immune system responses to a variety of infectious agents, such as M. tuberculosis and B. Pertussis, as well as various cancers. Qualified applicants will have the opportunity…

doi: 10.1093/nar/gkab1227. Online ahead of print. Regina Shebanova  1 , Natalia Nikitchina  1   2 , Nikita Shebanov  1 , Vladimir Mekler  3 , Konstantin Kuznedelov  3 , Egor Ulashchik  4 , Ruslan Vasilev  5   6 , Olga Sharko  4 , Vadim Shmanai  4 , Ivan Tarassov  2 , Konstantin Severinov  1   3   7 , Nina Entelis  2…

Introduction Most cases of pancreatic adenocarcinoma (PDAC) are diagnosed in the metastatic or locally advanced stage. It is the fourth leading cause of cancer death in the United States,1,2 with a 5-year overall survival (OS) around 10% in this country2 despite years of research and therapeutic development. For those patients…

1. Marder, S. R. & Cannon, T. D. Schizophrenia. N. Engl. J. Med. 381, 1753–1761. doi.org/10.1056/NEJMra1808803 (2019). Article  PubMed  CAS  Google Scholar  2. Keshavan, M. S. et al. Neuroimaging in Schizophrenia. Neuroimaging Clin. N. Am. 30, 73–83. doi.org/10.1016/j.nic.2019.09.007 (2020). Article  PubMed  Google Scholar  3. McCutcheon, R. A., Reis Marques, T….

Although 2021 was the year of viruses for the entire world population, it was even more so for growers, who were confronted with the infamous Tomato Brown Rugose Fruit Virus (ToBRFV). It has been quite a ride – which is, unfortunately, not over just yet. In order to give you…

CSIRO Postdoctoral Fellowship in Pathogen Genomics and Bioinformatics – Job posted on PostdocJobs.com CONNECT WITH US :    CSIRO Postdoctoral Fellowship in Pathogen Genomics and Bioinformatics Job Number: Date Posted: Dec 23, 2021 Application Deadline: Open Until Filled Job Description Acknowledgment of Country   CSIRO acknowledges the Traditional Owners of the…

Clinical Bioinformatics Analyst (m/w/d) PENZBERG, GERMANY Foundation Medicine is leading a transformation in cancer care, where each patient’s treatment is informed by a deep understanding of the molecular changes that contribute to their disease. As a molecular information company, we are focused on fundamentally changing the way in which patients…

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We…

1. Castle JT. Cholesteatoma pearls: practical points and update. Head Neck Pathol. 2018;12(3):419–29. Article  Google Scholar  2. Xie S, Wang X, Ren J, Liu W. The role of bone resorption in the etiopathogenesis of acquired middle ear cholesteatoma. Eur Arch Otorhinolaryngol. 2017;274(5):2071–8. Article  Google Scholar  3. Bhutta MF, Williamson IG,…

1 0q26 FGFR2 Break Apart FISH Probe Kit For Research Use Only Not for Use in Diagnostic Procedures 0q26 FGFR2 Break Apart FISH Probe Kit 09N /R2 Key to Symbols Used 09N /R2 Reference Number Lot Number Global Trade Item Number Centromere D0S294 0q26. Region FGFR2 5 ATE SHGC-529 Telomere…

This article was originally published here BMC Pediatr. 2021 Dec 11;21(1):566. doi: 10.1186/s12887-021-03003-5. ABSTRACT BACKGROUND: Kawasaki disease (KD) is a pediatric inflammatory disorder causes coronary artery complications. The disease overlapping manifestations with a set of symptomatically like diseases such as bacterial and viral infections, juvenile idiopathic arthritis, Henoch-Schönlein purpura, infection…

Next-generation sequencing (NGS) can better understand the genetic mechanisms associated with specific diseases and help promote personalise health care Preparing DNA for sequencing library is complicated and prone to human error, which can interfere with accurate sequencing results The new AVENIO Edge system is a fully automated solution for sample…

Next-generation sequencing (NGS) enables a better understanding of genetic mechanisms linked to specific diseases and is helping drive personalised healthcare Preparing DNA for sequencing libraries is complex and prone to human error, which can interfere with accurate sequencing results The new AVENIO Edge System is a fully-automated solution for the…

doi: 10.3389/fmolb.2021.737821. eCollection 2021. Affiliations Expand Affiliations 1 Laboratory For Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow, Russia. 2 Moscow Institute of Physics and Technology, Dolgoprudny, Russia. 3 OmicsWay Corp., Walnut, CA, United States. 4 Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia. 5…

As a leading global healthcare and diagnostics company, we strive to make advances toward greater certainty for our customers by providing them with cutting-edge technology that makes a real difference. We move to narrow the gap between doubt and confidence and work to achieve both incremental and transformational progress to…

PRIMARY care has for years been the cornerstone of the Australian health care system and GPs represent an integral part of it. As they are frequently responsible for the first, and sometimes only, contact of individuals with the health care system, they can profoundly affect a patient’s experience, expectations and…

Opportunity to join the computational team of a exciting biotech. Your new company I am currently working alongside an Oxford based biotech that focuses on clinical research and diagnostic solutions. Founded by a team from the University of Oxford, they have aims to progress the future of genetic-based medicine and…

A 20-minute Molecular Diagnosis Test Can Detect the Omicron Variant: Report On the 10th, POSTECH announced that a research group led by Professor Lee Jung-wook of the Department of Chemical Engineering had developed molecular diagnostic technology that can detect the Omicron variant in 20-30 minutes and will publish the results…

Evidence-Based Pharmacogenomic Testing Drug efficacy test results inform alternative medication selections when first-line treatment is ineffective with no guidelines for drug substitutions SAN FRANCISCO, CALIFORNIA, UNITED STATES, December 12, 2021 /EINPresswire.com/ — U.S. and Hong Kong-based Rainbow Genomics launches the Rainbow Psycho-Pharmacogenomic(TM) Testing Services enabling physicians to improve outcomes of…

Korean researchers have developed molecular diagnostics technology that can detect Omicron Seoul: Korean researchers have developed molecular diagnostics technology that can detect Omicron variants. The technology development has been currently completed, and it is expected to take time for commercialization. POSTECH announced on the 10th that a research team led…

Natera has announced the launch of Prospera with quantification, the only cell-free DNA (cfDNA) test for kidney rejection that provides three values—the quantity of donor-derived cfDNA (dd-cfDNA), fraction of dd-cfDNA, and total cfDNA—on every report. Combining these three metrics has been shown to improve sensitivity when evaluating transplant rejection, compared…

NuProbe USA Inc . is looking for a Staff/Senior Scientist to lead the IVD project development program at NuProbe to support both research and in vitro diagnostic (IVD) assays for use in medical research, clinical trials, regulatory submissions, and clinical diagnostic use.  NuProbe USA is a rapidly growing company and…

On the one hand, I really liked the diversity of the bioinformatics program, and, with a degree in bioinformatics, there are many possible career paths. Updated on 2 December 2021. Exact wages will depend on experience and the industry an individual works in. Working experience with structural antigen analyses and…

Today, three biotech companies, Innocoll Biotherapeutics, Genapsys, and Adicet Bio, announced relocation and expansion plans. Avison Young, a global commercial real estate company, announced that Innocoll Biotherapeutics opened a new office in Princeton, N.J. Innocoll is a biotherapeutics pharmaceutical company focused on developing and commercializing technologies to answer unmet health-care needs….

Next-Generation Sequencing (NGS) technology has led to a new era of studying microorganisms. Using this tool, our knowledge and understanding of microbiology has expanded at a rapid pace compared to traditional methods that rely on cell culture, microscopy, serology, and polymerase chain reaction (PCR). At the community level, microorganisms…

**Description** UPMC Presbyterian is hiring a Genome Bioinformatics Analyst to join the Molecular and Genomic Pathology Laboratory (MGP) team! This role will work a daylight schedule Monday through Friday. No weekends or holidays are required! The Molecular and Genomic Pathology Laboratory (MGP) is a dynamic state-of-the-art clinical laboratory that prides…

Recent genomic profiling studies revealed that approximately 40% of patients with biliary tract cancers harbor actionable genomic mutations. The advances in the understanding and characterization of biliary tract cancers (BTCs), particularly intrahepatic cholangiocarcinoma (iCCA), and genomic profiling over the past decade have led to a rapid expansion of available treatment…

1. Metser, U., Hussey, D. & Murphy, G. Impact of (18)F-FDG PET/CT on the staging and management of follicular lymphoma. Br. J. Radiol. 87, 20140360 (2014). CAS  Article  Google Scholar  2. Freedman, A. & Jacobsen, E. Follicular lymphoma: 2020 update on diagnosis and management. Am. J. Hematol. 95, 316–327 (2020)….

Raw Building Data—API Call Example The API Portal provides access to building and equipment information including raw asset data, HVAC faults, and calculated KPIs. Building teams are leveraging these powerful insights to inform workflow management, capital planning, risk assessment, maintenance prioritization, and resource planning. BOSTON (PRWEB) December 09, 2021 …

Introduction According to the cancer statistics reported in 2020, hepatocellular carcinoma (HCC) is the main type of Primary Carcinoma of the Liver and the second leading causes of cancer-related death globally, with a five-year survival rate < 20%.1 Currently, surgical resection, a standard therapy for HCC, contributes to the prognosis…

Ian Bolland caught up with Chris Hughes, managing director UK & Ireland of PerkinElmer, to discuss how its genome sequencing technology is used in newborn babies.  Many parents will be familiar with the heel prick test following a child’s birth and there is a good chance that PerkinElmer’s technology has been behind…

[Gettyimages Bank] SEOUL — South Korean researchers have developed a diagnostic technology that can detect the Omicron variant in 20 minutes. Researchers were able to acquire results in several days, opening the way for health officials to respond quickly even if a new variant occurs. Diagnostic kits can be easily made…

NEW YORK – Qiagen and Denovo Biopharma said on Thursday that they are collaborating to develop a blood-based companion diagnostic test to identify patients expressing a genomic biomarker who are likely to respond to Denovo’s investigational DB102 treatment for diffuse large B-cell lymphoma. Under the agreement, Qiagen will develop an…

News and research before you hear about it on CNBC and others. Claim your 1-week free trial to StreetInsider Premium here. QIAGEN (NYSE: QGEN) and Denovo Biopharma LLC today announced a collaboration to develop a blood-based companion diagnostic (CDx) test to identify patients expressing Denovo Genomic Marker 1 (DGM1TM) who…

– QIAGEN’s blood-based test will help to identify patients with Diffuse Large B-Cell Lymphoma (DLBCL) likely to respond to Denovo’s new investigational cancer treatment DB102 – The partners seek FDA premarket approval (PMA) of the companion diagnostic test in tandem with the new drug application (NDA) approval. SAN DIEGO and…

Qiagen And Denovo Biopharma Partner To Develop Companion Diagnostic Test For Treatment Of Diffuse Large B-Cell Lymphoma Published: 12/09/2021 14:36 GMT Qiagen NV (QGEN) – Denovo Biopharma and Qiagen Partner to Develop Companion Diagnostic Test for Treatment of Diffuse Large B-cell Lymphoma (dlbcl).Partners Seek FDA Premarket Approval (pma) of Companion…

Sequence information Variant position:  205 The position of the amino-acid change on the UniProtKB canonical protein sequence. Protein sequence length:  496 The length of the canonical sequence. Location on the sequence:   ERSLDTLLEAVESRGGVPGG  C VLVPRADLRLGGQPAPPQLL The residue change on the sequence. Unless the variant is located at the beginning or at the end of…

Sequence information Variant position:  4075 The position of the amino-acid change on the UniProtKB canonical protein sequence. Protein sequence length:  4374 The length of the canonical sequence. Location on the sequence:   GQDAGGLLREWYMIISREMF  N PMYALFRTSPGDRVTYTINP The residue change on the sequence. Unless the variant is located at the beginning or at the end of…

Oral and Poster Abstracts 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster III Translational Research Maher Albitar, MD1*, Andrew Ip, MD, MSc2, Andre H. Goy, MD3*, Jeffrey Justin Estella, BS, MS1*, Ivan De Dios, BS1*,…

NCAA president Mark Emmert believes that being a university president is a very, very difficult. How tough does he think it is? Tougher than literally any other job. NCAA president Mark Emmert: “Being a university president is the hardest job in America” — Brett McMurphy (@Brett_McMurphy) December 8, 2021 I’ll…

Plain Language Summary Fluoropyrimidine (FP; 5-FU, capecitabine) is a common chemotherapy used to treat many different cancers, including cancer of the colon and rectum, upper digestive tract, breast and head and neck. Cancer patients who receive FP chemotherapy are at risk of developing severe side effects from their treatment. A…

Background: Exosomal microRNAs (miRNAs) are potential biomarkers for a variety of tumors but have not yet been studied in diffuse large B-cell lymphoma (DLBCL). Here, we investigated the use of exosomal miRNAs in DLBCL diagnosis and prognosis. Methods: A total of 256 individuals, including 133 DLBCL patients, 94 healthy controls…

Published: 12/09/2021 06:38 GMT Qiagen NV (QGEN) – Qiagen and Denovo Biopharma Partner to Develop Companion Diagnostic Test for Treatment of Diffuse Large B-cell Lymphoma (dlbcl).Qiagen’s Blood-based Test Will Help to Identify Patients With Diffuse Large B-cell Lymphoma (dlbcl) Likely to Respond to Denovo’s New Investigational Cancer Treatment Db102tm.Partners Seek…

SAN DIEGO, Dec. 9, 2021 /PRNewswire/ — Illumina, Inc. (NASDAQ:ILMN), today announced that it is supporting a national precision medicine study in Norway to assess the efficacy of blood-based comprehensive genomic profiling (CGP) in cancer therapy selection testing. The study will also evaluate the cost-effectiveness of implementing blood-based CGP in…

QIAGEN’s blood-based test will help to identify patients with Diffuse Large B-Cell Lymphoma (DLBCL) likely to respond to Denovo’s new investigational cancer treatment DB102TM The partners seek FDA premarket approval (PMA) of the companion diagnostic test in tandem with the new drug application (NDA) approval. New master collaboration agreement adds…

We are seeking multiple Experimental and Bioinformatics research positions (including Postdoctoral Research Fellows and Research Associate) to join the Alzheimer’s Network Medicine and Artificial Intelligence (AI) research group (www.lerner.ccf.org/gmi/cheng/) led by Dr. Feixiong Cheng at the Genomic Medicine Institute, Cleveland Clinic Lerner Research Institute, and Department of Molecular Medicine at…

(RTTNews) – Qiagen (QGEN) and Denovo Biopharma said that they have collaborated to develop a blood-based companion diagnostic test to identify patients expressing Denovo Genomic Marker 1 who are likely to respond to Denovo’s investigational cancer drug DB102 for treatment of diffuse large B-cell lymphoma or DLBCL, one of the…

DUBLIN, Dec. 8, 2021 /PRNewswire/ — The “Next Generation Sequencing Market, Global Forecast, Impact of COVID-19, Industry Trends, Growth, Opportunity By Types of Test, Company Analysis” report has been added to ResearchAndMarkets.com‘s offering. According to the report, the Global Next Generation Sequencing Market will reach US$ 34.8 Billion by 2027….

Genapsys, a Silicon Valley-based bioscience company, will expand into Westminster and plans to hire up to 250 employees for its new location, officials said Wednesday. Genapsys develops technology that it says will pave the way for universal access to genomic information and make more advanced DNA studies easier for both…

James Guys, does anyone know the answer? get the spacer of sgrna will hybridize with this sequence of dna from the fragment shown below? from EN Bilgi. Solved The spacer of sgRNA will hybridize with this sequence Answer to Solved The spacer of sgRNA will hybridize with this sequence Do…

The Hide Lab at Harvard Medical School and BIDMC seeks a bioinformatics/computational biology postdoctoral fellow for training. We focus on target discovery, and diagnostic and therapeutic applications for Alzheimer’s Disease. The position is under the direction of Dr. Winston Hide (Systems RNA medicine) and is available immediately. For a list of publications…

A new systematic review of the validated monogenic causes of male infertility strengthens the evidence base for emerging gene-disease relationships; the review hopes to encourage more routine genetic testing in clinics and identify gaps in our knowledge of male infertility genetics. In less than two years, the number of genes…

. 2021 Nov 17;2021:6287280. doi: 10.1155/2021/6287280. eCollection 2021. Affiliations Expand Affiliations 1 Department of Infectious Diseases, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, China. 2 Institute of Applied Genomics, Fuzhou University, Fuzhou 350108, China. Item in Clipboard Xiaoling Yu et al. Biomed Res Int. 2021. Show details Display options…

Impact Healthcare Roche is dedicated to advancing personalized healthcare by creating diagnostics and treatments tailored to individual genetic and disease profiles. As part of this mission, Roche Sequencing Solutions is unifying next-generation sequencing with the goal of making it routine sample in – result out. Make a Big Difference Cancer…

NEW YORK – At the European Society for Medical Oncology Congress this week, precision oncology assay developer Lucence presented data that demonstrated its amplicon-based LiquidHallmark assay could be used to personalize care for people with advanced urothelial carcinoma. LiquidHallmark is a laboratory-developed test based on the company’s AmpliMark next-generation sequencing platform…

The European Commission has delivered a list of objections to Illumina and Grail over their decision to proceed with their multibillion-dollar merger despite the regulators’ ongoing investigation. It also noted the measures watchdogs plan to take to cordon off the potential effects of the deal on the wider market. The commission…

GAITHERSBURG, Md., Sept. 21, 2021 /PRNewswire/ — GeneDx, Inc., a leader in genomic analysis, a wholly owned subsidiary of BioReference Laboratories, Inc., an OPKO Health company (NASDAQ: OPK), today announced it has completed clinical genetic exome sequencing for more than 300,000 patients, making the company’s dataset the largest of its kind…

GAITHERSBURG, Md., Sept. 21, 2021 GAITHERSBURG, Md., Sept. 21, 2021 /PRNewswire/ — GeneDx, Inc., a leader in genomic analysis, a wholly owned subsidiary of BioReference Laboratories, Inc., an OPKO Health company (NASDAQ:OPK), today announced it has completed clinical genetic exome sequencing for more than 300,000 patients, making the company’s dataset…

The Biostar Herald publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. You too can submit links here. This edition of the Herald was brought to you by contribution from Istvan Albert, and was edited by Istvan…

Genetic counselors bridge the gap between the technical, scientific information of a genetic disease diagnosis or test result and the patient’s understanding of how their genetic information affects their health. With the widespread use of DNA sequencing in cancer and increasingly more conditions in the age of precision medicine, genetic…

Illumina Ventures, the independently managed venture capital firm bankrolled by the DNA sequencing giant, has closed its second investment fund, amassing $325 million in new commitments. ​The proceeds will be used to support genomics-focused, early-stage startups looking to build new clinical diagnostics and life science research tools as well as targeted…

News and research before you hear about it on CNBC and others. Claim your 1-week free trial to StreetInsider Premium here. Boca Raton, Florida and Jerusalem, Israel–(Newsfile Corp. – September 20, 2021) – NovelStem International Corp. (OTC Pink: NSTM), a biotechnology company focused on the stem cell-based technology platform developed…

Introduction Prostate cancer (PCa) is one of the most common genitourinary system malignant tumor in men worldwide. In Asian countries, many patients with PCa are often diagnosed at an advanced stage maybe mostly because of a large population base with relatively backward economic development and imperfect cancer screening system of…

    This package is for version 2.13 of Bioconductor; for the stable, up-to-date release version, see marray. Exploratory analysis for two-color spotted microarray data Bioconductor version: 2.13 Class definitions for two-color spotted microarray data. Fuctions for data input, diagnostic plots, normalization and quality checking. Author: Yee Hwa (Jean) Yang…

Why do people who have never smoked get lung cancer? In recent research, three subtypes of lung cancer were classified by non-smokers. (Photo: utah51/stock.adobe.com) Analysis: Lung cancer in non-smokers Even if smoking is the main risk factor for developing lung cancer, it is not uncommon for people who have never…

About PersistentWe are a trusted Digital Engineering and Enterprise Modernization partner, combining deep technical expertise and industry experience to help our clients anticipate what’s next. Our offerings and proven solutions create unique competitive advantage for our clients by giving them the power to see beyond and rise above. We are…

September 17, 2021 2 min read Source/Disclosures Published by: Disclosures: The authors report no relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email…

1. Dudas, G. et al. Virus genomes reveal factors that spread and sustained the Ebola epidemic. Nature 544, 309–315 (2017). ADS  CAS  Article  Google Scholar  2. Kafetzopoulou, L. E. et al. Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak. Science 363, 74–77 (2019). ADS  CAS  Article …

Most of us have credit cards, but there are still some people that do not. Skin lesion detection and classification is always observed as a difficult problem to solve. Got it. We then applied dropout again to further prevent overfitting. This problem is important as it will potentially save a…

WSU scientists are researching a rapidly spreading disease that causes elk to suffer deformed hooves, lameness and increasingly poor health that often can lead to death. (Photo from WSU Elk Hoof Disease Research project) PULLMAN, Wash — Washington State University’s Elk Hoof Disease Research team has discovered one way in…

Associate Director of Bioinformatics – A.I. Genomics Hartmann Young are exclusively partnered with a pioneer within precision metagenomics headhunt for an Associate Director Bioinformatics. The company are working with excitin technology that provides hands-off, AI-powered automated improved pathogen detection, genomic profiling, and quantification of tens of thousands of pathogens from…

HONG KONG, Sept. 16, 2021 /PRNewswire/ — Hong Kong-based venture capital firm Beyond Ventures is pleased to support today’s announcement by the firm’s first investee company, Prenetics, that Prenetics, a global leader in genomic and diagnostic testing is set to merge with Artisan Acquisition Corp. (Nasdaq: ARTAU, “Artisan”), to become…

Introduction Thyroid cancer (TC) is a common endocrine malignancy with a rapidly increasing incidence worldwide, and the estimated new cases and deaths are notably higher in women than in men.1 Papillary thyroid carcinoma (PTC) is identified as the most common pathological type of TC, and accounts for approximately 80–85% of…

The gene-editing tool CRISPR is moving toward the market, promising better tests, disease cures — and maybe even a woolly mammoth. The big picture: CRISPR is already a historic scientific achievement, but we’re just now entering the moment when it will begin to impact patients and possibly the planet. Driving…

Next-Generation Sequencing Utilizing Tumor Tissue and/or Blood The identification of actionable genomic alterations in tumors such as mCRC was once performed by Sanger DNA sequencing of tumor DNA that was extracted from fixed paraffin-embedded tumor tissue, but this has now been replaced by next-generation sequencing (NGS), which allows for larger-scale…

Introduction Coronary artery disease (CAD) is a complex pathology associated with behavioral and environmental factors.1–3 CAD shows high prevalence and is associated with a high fatality rate among cardiovascular diseases. The main manifestations of CAD are stable or unstable angina pectoris and identifiable or unrecognized myocardial infarction.4 The main risk…

There Will Be Disaster: Tinashe Mugabe Says He Is Against Compulsory DNA Testing At Birth     Tinashe Mugabe, the host of the popular television show, The Closure DNA Show, has said that he is against compulsory DNA tests at birth. Mugabe, who is affectionately known as the DNA Man,…

Peptone is using science to build the world’s first protein engineering operating system, combining AI with computational molecular physics. Above, a 3D illustration of proteins. Photo: Getty Life comes at you fast. At one point Peptone, a computational biophysics company, had been rejected by more than 150 investors. Now, it…