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Tag: DOCK2
Cancers | Free Full-Text | High G9a Expression in DLBCL and Its Inhibition by Niclosamide to Induce Autophagy as a Therapeutic Approach
1. Introduction Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignant lymphoid neoplasm, which accounts for 40% of all malignant lymphoid neoplasms and includes morphologically and molecularly heterogeneous disease subtypes [1,2]. According to gene expression profiling, different forms of DLBCL are subdivided into germinal center B-cell-like (GCB-DLBCL) and activated B-cell-like…
Identification of macrophage-related genes in sepsis-induced ARDS using bioinformatics and machine learning
Screening of differentially expressed genes in GSE32707 According to the screening criteria of differentially expressed genes, there were 489 differentially expressed genes between the control and sepsis groups, of which 152 genes were downregulated in sepsis patients and 337 genes were upregulated in sepsis patients (Fig. 1A). In contrast, there were…
Extra-hematopoietic immunomodulatory role of the guanine-exchange factor DOCK2
Cell isolation, reprogramming and culture Approval was obtained for human cell and tissue sample collection and genetic reprogramming from the Institutional Review Board (protocols 19–252, 18–243, 21–060, 19–284 and 415-E/1776/4-2014, Ethics Committee of the province of Salzburg). Adult samples were collected in accordance with the Declaration of Helsinki after written…
Is there a way to find the GWAS traits to a gene programmatically?
Is there a way to find the GWAS traits to a gene programmatically? 0 Hello folks, I would like to use a gene name (e.g. DOCK2) or its ENSEMBL ID as input, and get as output the reported GWAS traits to the respective gene. I did give a look into…