Tag: EdU

Senior Bioinformatics Analyst in New York, NY for Weill Cornell Medicine

Details Posted: 09-Feb-24 Location: New York, New York Salary: Open Categories: Academic/Faculty Medical – Clinical Senior Bioinformatics Analyst Title: Senior Bioinformatics Analyst Location: Upper East Side Org Unit: Steven Josefowicz Lab Work Days: Monday-Friday Exemption Status: Exempt Salary Range: $108,600.00 – $126,600.00 *As required under NYC Human Rights Law Int…

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Preparation and recognition mechanism study of an scFv targeting chloramphenicol for a hybridization chain reaction-CRISPR/Cas12a amplified fluoroimmunoassay

. 2024 Mar 8:1293:342283. doi: 10.1016/j.aca.2024.342283. Epub 2024 Jan 22. Affiliations Expand Affiliations 1 College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China. 2 Medical College, Nankai University, Tianjin, 300500, China. Electronic address: wangshuo@nankai.edu.cn. 3 College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China….

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The Henry M. Jackson Foundation for the Advancement of Military Medicine hiring Senior Bioinformatics Scientist in Bethesda, MD

Join the HJF Team!The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a nonprofit organization dedicated to advancing military medicine. We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians alike….

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NYU High Performance Computing – HPC Projects

Depending on your role, you will see the corresponding interface at the Portal. HPC Project Owner You can register an HPC project if you are a full-time faculty and sponsoring a currently active HPC account for research or instruction. If you are a part-time faculty teaching a course, please get…

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Short tandem repeat mutations regulate gene expression in colorectal cancer

A novel STR panel for human protein-coding genes To explore STR mutations in CRC, we first annotated STRs in the introns, exons, and promoter sequence of all protein-coding genes in the GRCh38 reference genome (“Methods”). We discarded STR loci for which genotyping was expected to be inaccurate due to genomic…

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Faulty DNA disposal system causes inflammatio

image:  Endosomes (magenta) collect around mitochondria (blue) after infection with virus HSV-1, which attacks mtDNA (green) and causes its release. view more  Credit: Salk Institute LA JOLLA (February 8, 2024)—Cells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from…

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Special Episode 3: PhiX / UMIs / QC

Podcast: Explain Podcast Erschienen: 09.02.2024Dauer: 01:10:43 Getting the most out of Machines Chapters: 04:30 PhiX 14:30 low complexity 19:30 UMIs 32:10 FastQC 43:00 MultiQC 56:40 PycoQC PhiX concentrations for loading a validation run: knowledge.illumina.com/instrumentation/general/instrumentation-general-reference_material-list/000001536 Dnatech on why UMIs are used: dnatech.genomecenter.ucdavis.edu/faqs/what-are-umis-and-why-are-they-used-in-high-throughput-sequencing/ BMH learning on UMIs: www.youtube.com/watch?v=sRPMsnhIBK0 FastQC for QC of…

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Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis

Bacteria Strain Cori.ST1911 was isolated from fresh stool of 20-week-old C57/BL6J mice fed a HFD at the Animal Center of the West China Hospital of Sichuan University. Briefly, faecal particles were ground with a glass grinding rod and suspended in sterile phosphate-buffered saline (PBS). After gradient dilution, the suspension was…

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(PDF) Regulation of mitochondrial gene expression the epigenetic enigma | Marianne Rots

(PDF) Regulation of mitochondrial gene expression the epigenetic enigma | Marianne Rots – Academia.edu Academia.edu uses cookies to personalize content, tailor ads and improve the user experience. By using our site, you agree to our collection of information through the use of cookies. To learn more, view our Privacy Policy. ×…

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Bioconductor – dcanr

DOI: 10.18129/B9.bioc.dcanr     This package is for version 3.12 of Bioconductor; for the stable, up-to-date release version, see dcanr. Differential co-expression/association network analysis Bioconductor version: 3.12 Methods and an evaluation framework for the inference of differential co-expression/association networks. Author: Dharmesh D. Bhuva [aut, cre] Maintainer: Dharmesh D. Bhuva <bhuva.d…

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Plug-and-play smart transistor bio-chips implementing point-of-care diagnosis of AMI with modified CRISPR/Cas12a system

. 2024 Feb 15:246:115909. doi: 10.1016/j.bios.2023.115909. Epub 2023 Dec 5. Affiliations Expand Affiliations 1 School of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan, 430065, PR China; Department of Pharmacy, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, PR China. 2 School of Laboratory…

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Generate topology file for glucose – User discussions

horlust December 29, 2023, 10:15am 1 GROMACS version: 2021.4-2GROMACS modification: No Hello everyone! I am fairly new to GROMACS. I’ve been able to successfully run simulations for some small molecules with the OPLS-AA force field. My problem has always been the generation of the topology files. Using pdb2gmx seems impossible…

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DNA Sequencing May Unlock the Future of Digital Storage | Washington D.C. & Maryland Area

Storage devices such as hard drives and solid-state drives don’t last forever. They are fragile, challenging to maintain, and can become obsolete quickly, causing considerable harm and loss if a device becomes unusable. Further, as data creation will soon outpace the amount of available storage space, new digital storage options…

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Association of PIK3CA Mutation With Pathologic Complete Response and Outcome by Hormone Receptor Status and Intrinsic Subtype in Early-Stage ERBB2/HER2-Positive Breast Cancer | Oncology | JAMA Network Open

Key Points Question  What is the association of PIK3CA mutations, response to therapy, and outcome by hormone receptor (HR) status and intrinsic subtype among patients with ERBB2/HER2-positive early breast cancer (EBC) treated in a clinical trial? Findings  In this cohort study of 184 patients enrolled in the phase 3 trial…

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Genetic sequencing uncovers unexpected source

image:  A NASA image containing visible and infrared data revealing the presence of dissolved organic matter – including potential antibiotic-resistant pathogens – in the waterways along coastal North Carolina after Hurricane Florence. view more  Credit: NASA CHAMPAIGN, Ill. — Researchers report in the journal Geohealth that local rivers and streams…

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UChicago Medicine experts showcase blood cancer research at 65th ASH Annual Meeting

Faculty and trainees from the University of Chicago Medicine Comprehensive Cancer Center (UCCCC) joined the world’s largest hematology community to discuss the latest updates in blood cancers at the 65th American Society of Hematology (ASH) Annual Meeting and Exposition held December 9-12, 2023 in San Diego and online. At the meeting,…

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Senior Bioinformatics Scientist in Chicago, IL for University of Chicago (UC)

Details Posted: 19-Dec-23 Location: Chicago, Illinois Type: Full-time Salary: Open Categories: Research – Laboratory/Non-Laboratory Staff/Administrative Location: Chicago, IL Job Description: Development of an integrated data warehouse for symbiote including clinical, microbiome sequence, and metabolomic data.  Management of DFI Biobank, MMF, and HMMF data within the Symbiote platform. Functional analysis of…

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Senior Bioinformatics Scientist @ University of Chicago

Department BSD DFI – Translational Informatics About the Department The Duchossois Family Institute focuses on the role of commensal bacteria in enhancing disease resistance and is using genomic and metabolomic platforms to characterize the microbiome and its metabolites. Computational and bioinformatic expertise is required to understand how commensal bacteria impact…

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Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L

Loss of ASH2L prevents cell proliferation We have studied the molecular and cellular consequences of Ash2l loss in mouse embryo fibroblasts (MEFs) with floxed Ash2l alleles and an inducible Cre-ER recombinase (iMEF-Ash2lfl/fl-Cre-ER). While the knockout of Ash2l was rapid, the downstream effects, including the decrease in promoter-associated H3K4me3, altered gene…

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DADA2 formatted 16S rRNA gene sequences for both bacteria & archaea

Description This version is to stay up to date with the improvements and increase in 16S rRNA gene sequences (SSU) added to the GTDB release 214.1.  Please read this post for the stats on the updates. gtdb.ecogenomic.org/stats/r214 . There has been no change to the RDP-RefSeq reference database If anyone…

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Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir

Participants and blood collection A total of n = 23 HIV-1 seropositive individuals on stably suppressive ART were included in this study (Supplementary Table 1). Participants were recruited at Ghent University Hospital. 2/23 individuals are female, 21/23 are male; the limited representation of female individuals in our study is a direct reflection of…

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Elevating intracellular action potential recording in cardiomyocytes: A precision-enhanced and biosafe single-pulse electroporation system

. 2023 Nov 24:246:115860. doi: 10.1016/j.bios.2023.115860. Online ahead of print. Affiliations Expand Affiliations 1 Department of Chemistry, Zhejiang-Israel Joint Laboratory of Self-Assembling Functional Materials, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 310058, China. 2 State Key Laboratory of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of…

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Diversity and dissemination of viruses in pathogenic protozoa

Wang, A. L. & Wang, C. C. Viruses of the protozoa. Annu. Rev. Microbiol. 45, 251–263 (1991). Article  CAS  PubMed  Google Scholar  Banik, G., Stark, D., Rashid, H. & Ellis, J. Recent advances in molecular biology of parasitic viruses. Infect. Disord. – Drug Targets 14, 155–167 (2015). Article  Google Scholar …

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Grant-Funded Researcher (B) CREST 2, School of Computer Science job with UNIVERSITY OF ADELAIDE

(Level B) $107,276 – 126,984 per annum plus an employer contribution of 17% superannuation applies. Fixed term position for 18 months The School of Computer Science offers high quality accredited degrees in computer science, and software engineering, has strong links with industry and a robust research ethos. This role will…

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Postdoctoral Research Associate in Educational Data Science job with UNIVERSITY OF SYDNEY

Full time, fixed term for 2 years Located at the School of Computer Science, Camperdown Campus Base Salary $105K – $108K p.a., + 17% superannuation About the opportunity Established as the first computer science department in Australia, the School of Computer Science (SCS) is research intensive…

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World Aquaculture Society | R Syntax and Applications: Data Analysis, Visualization, and Dissemination

The U.S. Aquaculture Society (USAS) and the Fish Culture Section of the American Fisheries Society (AFSFCS) are offering a Continuing Education R Syntax and Applications Workshop at the upcoming Aquaculture America Meeting in San Antonio (meeting dates February 18 – 21, 2024):   Date: February 18, 2024 Time: 8:30 am –…

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Globus and GROMACS changes | PSC

Following this week’s maintenance period on Bridges-2, the following changes have been made. Globus For Globus/GridFTP transfers to/from Bridges-2, please use the new endpoint labelled “PSC Bridges-2 Globus Connect Server 5 Endpoint”. The new Globus CLI endpoint’s UUID is ca35a4c4-6e61-4aaa-8bc1-67b812c1f337.   GROMACS If you are a user of Gromacs, you…

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Conserved and divergent gene regulatory programs of the mammalian neocortex

Nucleus preparation from frozen brain tissue for Chromium single-cell multiome ATAC and gene expression analysis M1 tissue was obtained from three human donors (male, aged 42, 29 and 58 years), three macaque donors (male, aged 6 (Macaca mulatta), 6 (M. mulatta) and 14 (Macaca fascicularis) years), three marmoset (Callithrix jacchus)…

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Unraveling the genome of Bacillus velezensis MEP218, a strain producing fengycin homologs with broad antibacterial activity: comprehensive comparative genome analysis

Whole genome sequencing and analysis To understand the mechanisms underlying the biological control capability of bacterial pathogens, the complete genome of MEP218 was sequenced, assembled, and deposited in the GenBank database under the accession number CP042864.2. The genome of MEP218 consists of a single circular chromosome of 3,944,892 bp with a…

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Bioconductor – QTLExperiment (development version)

DOI: 10.18129/B9.bioc.QTLExperiment   This is the development version of QTLExperiment; for the stable release version, see QTLExperiment. S4 classes for QTL summary statistics and metadata Bioconductor version: Development (3.19) QLTExperiment defines an S4 class for storing and manipulating summary statistics from QTL mapping experiments in one or more states. It…

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Postdoctoral Research Fellow in Laser Physics and Engineering job with MACQUARIE UNIVERSITY – SYDNEY AUSTRALIA

We are seeking qualified two Postdoctoral Research Fellows to join the School of Engineering with an international reputation for producing high quality research outcomes in Laser Physics and Engineering. The successful candidates will make a significant contribution to the development of high-power pulsed fibre lasers that will be used for…

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Researcher in Bioinformatics job with UNIVERSITY OF SYDNEY

Full-time 12 -24-month fixed-term position Research Fellow (Level A) in the Charles Perkins Centre on the Camperdown Campus Base salary starting from $83, 454 plus 17% superannuation About the opportunity The Imaging and Phenotyping Laboratory is a cross-disciplinary, data-intensive scientific group with the mission to revolutionise…

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Single-cell analysis of chromatin accessibility in the adult mouse brain

Tissue preparation and nucleus isolation All experimental procedures using live animals were approved by the SALK Institute Animal Care and Use Committee under protocol number 18-00006. Adult C57BL/6J male mice were purchased from Jackson Laboratories. Brains were extracted from 56–63-day-old mice and sectioned into 600 µm coronal sections along the anterior–posterior…

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Cancers | Free Full-Text | In Vitro Organoid-Based Assays Reveal SMAD4 Tumor-Suppressive Mechanisms for Serrated Colorectal Cancer Invasion

Original submission received: 21 November 2023 / Revised: 8 December 2023 / Accepted: 11 December 2023 / Published: 13 December 2023 Round 1 Reviewer 1 Report Comments and Suggestions for Authors Dear authors, thank you for this valuable piece of work. Should the other reviewer(s) recommend edits to your work,…

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Whole mitochondrial and chloroplast genome sequencing of Tunisian date palm cultivars: diversity and evolutionary relationships | BMC Genomics

Johnson DV, Al-Khayri JM, Jain SM. Introduction: Date Production Status and Prospects in Africa and the Americas. In: Al-Khayri J, Jain S, Johnson D, editors. Date Palm Genetic Resources and Utilization: Volume 1: Africa and the Americas. Springer Netherlands, Dordrecht; 2015. p. 1–18. doi.org/10.1007/978-94-017-9694-1_1 Gros-Balthazard M, Hazzouri KM, Flowers JM. Genomic…

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OPS Molecular Pathology Bioinformatics Specialist job with University of Florida

OPS Molecular Pathology Bioinformatics Specialist Job No: 529638Work Type: Temp Part-TimeLocation: Main Campus (Gainesville, FL)Categories: Biology/Life Science, Information Technology, Grant or Research AdministrationDepartment: 29081100 – MD-PATH – UF PATH LABS Job Description Classification Title: OPS Molecular Pathology Bioinformatics Specialist Job Description: Overview: The Molecular Pathology Laboratory at the University of…

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Research Assistant – Bioinformatician (Cancer Science Institute) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The Pitt Lab is a leading computational research group at the Cancer Science Institute of Singapore dedicated to making groundbreaking discoveries in cancer genomics using cutting-edge machine learning techniques. Our research focuses on the causes and consequences of genome instability. We explore this by combining software development and…

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Computational Biology/Bioinformatics (3-309-1178) – Baltimore

The Center for Vaccine Development and Global Health (CVD) and the Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) seek applications for a faculty member with expertise in systems/computational biology and/or bioinformatics and demonstrated knowledge of the application of multiple omics-based approaches to immunology,…

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overlapping duplicate dispersed_repeat feature in stringtie

GFF Error: overlapping duplicate dispersed_repeat feature in stringtie 0 Hi. I got following error when I use stringtie. with repeatmasker annotation gff file and RNA-seq bam files which is already sorted with samtools. GFF Error: overlapping duplicate dispersed_repeat feature (ID=461) GFF Error: overlapping duplicate dispersed_repeat feature (ID=712) GFF Error: overlapping…

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Thyroid hormone-regulated chromatin landscape and transcriptional sensitivity of the pituitary gland

Mouse genetic models The ThrbHAB allele expresses TRβ proteins (TRβ1 and TRβ2) fused to a peptide with a hemagglutinin (HAx2) tag and a site for biotinylation by prokaryotic BirA ligase, modified from a published tag30. The tag was inserted at the endogenous Thrb gene by homologous recombination in W9.5 (129/Sv)…

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“Regulation of mRNA and circRNA as a Cause and Consequence of Aging in” by Rebekah Napier-Jameson

Abstract A role for RNA binding proteins in regulating lifespan has emerged. We identified a pair of neuronal RBPs, exc-7 and mbl-1, which display synthetic lifespan defects. Such a strong synthetic phenotype represented an opportunity to use transcriptomics to search for potential causative targets that are synthetically regulated. We identified…

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Research Assistant (Cancer Science Institute – Spatial Biology) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description This position is an appointment to Cancer Science Institute Microscopy and Multiplex Assays (MMA) Core. The MMA Core offers scientists a variety of paid services, ranging from basic histology processes to spatial proteomics and transcriptomics analysis. We are looking for a meticulous and dedicated Research Assistant to anchor the day-to-day running of…

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(PDF) Identification of Myostatin gene polymorphism using PCR-RFLP for improving carcass meat evaluation of Teleorman Black Head lambs | Cristina Lazar

(PDF) Identification of Myostatin gene polymorphism using PCR-RFLP for improving carcass meat evaluation of Teleorman Black Head lambs | Cristina Lazar – Academia.edu Academia.edu uses cookies to personalize content, tailor ads and improve the user experience. By using our site, you agree to our collection of information through the use…

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Noob Errors with GISTIC2

Hello, Shahin here.I am very happy that such a group exists.other than that, just want to thank you to make open source GenePattern, which saves us lots of work and saves lots of time. I am new to Gene analysis and because of that, trying to do a sample project.For…

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Phenotypic profiling of solute carriers characterizes serine transport in cancer

Cell culture All cell lines used in this study were cultured at 37 °C in 5% CO2 in a humidified incubator. Human cell lines were authenticated by STR profiling using Promega GenePrint 10 and tested for Mycoplasma using Mycoalert (Lonza). Other than HCT116 p21−/− (a gift of B. Vogelstein60) all cell…

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University of Southern Queensland hiring Research Fellow (Bioinformatics) in Toowoomba, Queensland, Australia

Building on its strengths as Australia’s leading regional University, UniSQ’s vision is to be renowned for innovation and excellence in education, student experience, research and engagement. Guided by our core values of respect, integrity and excellence, the University’s Strategic Plan 2021-2025 outlines our commitment to creating and sharing knowledge, transforming…

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(PDF) Molecular Characterization and Association of Local Isolates of Staphylococcus aureus on The Basis of 16 S rRNA in Poultry and Human in Pakistan | Rizwan Ashraf

(PDF) Molecular Characterization and Association of Local Isolates of Staphylococcus aureus on The Basis of 16 S rRNA in Poultry and Human in Pakistan | Rizwan Ashraf – Academia.edu Academia.edu uses cookies to personalize content, tailor ads and improve the user experience. By using our site, you agree to our…

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[slurm-users] Time spent in PENDING/Priority

We use Prometheus as our primary metric tool, and I recently added a metric for jobs in PENDING for the specific reason of “priority”. So we’ll have some nice data for when we are preparing for FY 2025, I suppose, the problem is for this past year we are stuck…

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Whole-genome long-read sequencing downsampling and its effect on variant-calling precision and recall

William T. Harvey1, Peter Ebert2,3,4, Jana Ebler2,4, Peter A. Audano5, Katherine M. Munson1, Kendra Hoekzema1, David Porubsky1, Christine R. Beck5,6, Tobias Marschall2,4, Kiran Garimella7 and Evan E. Eichler1,8 1Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195-5065, USA; 2Institute for Medical Biometry and Bioinformatics, Medical Faculty,…

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Why claims of a new ‘genetic vaccine’ being given to Australian children don’t align with reality

CheckMate December 8, 2023 This week, we debunk viral social media posts that claim a new “genetic vaccine” has been added to the national vaccine schedule for children aged 2-6 months. We also show why the “mother of all revelations” was more fizzer than Pfizer, and identify some of the…

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Bioconductor – bcellViper (development version)

DOI: 10.18129/B9.bioc.bcellViper   This is the development version of bcellViper; for the stable release version, see bcellViper. Human B-cell transcriptional interactome and normal human B-cell expression data Bioconductor version: Development (3.19) This package provides a human B-cell context-specific transcriptional regulatory network and a human normal B-cells dataset for the examples…

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Senior Bioinformatics Scientist – 127022

UCSD Layoff from Career Appointment: Apply by 12/08/2023 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor. Special Selection Applicants: Apply by 12/20/2023. Eligible Special Selection clients should contact their Disability Counselor for assistance. This position will work a hybrid schedule which includes a combination…

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University of Connecticut Single Cell RNA-seq Workshop December 12-15, 2023

News:University of Connecticut Single Cell RNA-seq Workshop December 12-15, 2023 0 Join UConn’s Computational Biology Core for a Single Cell RNAseq Workshop December 12-15, 2023 Scope of the workshop: Introduction to different data file formats. Understanding the Considerations while designing single-cell RNA-seq experiments, Hands on steps to convert raw single-cell…

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Functional conservation of specialized ribosomes bearing genome-encoded variant rRNAs in Vibrio species

Fig 1. rrnI-dependent expression of HspA in V. vulnificus MO6-24/O strains. (A) Schematic representation of the allele-specific RT-PCR analysis analyzing the relative amounts of I-rRNA or G-rRNA. (B) The number of I-rRNA or G-rRNA amplicons and other rRNAs amplified from the cDNA of the MO6 WT, MO6+rrnG, and MO6+rrnI strains…

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Identification and validation of key miRNAs for colon cancer

Introduction With nearly 2 million new cases and 1 million deaths worldwide in 2020, colorectal cancer is the third-most common cancer and the second leading cause of cancer-related deaths.1 According to data from the US Surveillance, Epidemiology and End Results program and the National Program of Cancer Registries program, the…

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Key Genes for Pyroptosis-induced Salivary Gland Inflammation

Kaiyuan Zhang,1,&ast; Ziyue Luo,1,&ast; Xinchao Zhu,1 Xinyi Yao,1 Dingqi Lu,2 Liying Chen,1 Tao Hong,1 Yating Ren,1 Xinchang Wang3 1Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310053, People’s Republic of China; 2First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310053, People’s Republic of China;…

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The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

Cell line and growth assays Cell lines were grown in Roswell Park Memorial Institute-1640 medium (RPMI-1640) with 1% penicillin–streptomycin (10,000 U ml−1) and 10% FBS or in Iscove’s modified Dulbecco’s medium (IMDM) with 1% penicillin–streptomycin (10,000 U ml−1), l-glutamine (200 mM) and 10% FBS in a humidified incubator with 5% CO2 maintained at 37 °C. Drugs…

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Advances in Gene Editing Technology: Revolutionizing Healthcare and Beyond | by Amirali Banani | Dec, 2023

Amirali Banani December 3, 2023 Credit: vchal/Shutterstock “The power to control our species’ genetic future is awesome and terrifying. Deciding how to handle it may be the biggest challenge we have ever faced.” ― Jennifer A. Doudna In recent years, gene editing technology has witnessed remarkable advancements, transforming the landscape…

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Investigator in Human Induced Pluripotent Cells (iPSCs) in Alzheimer’s Disease Research in Birmingham, AL for University of Alabama, Birmingham

Details Posted: 04-Dec-23 Location: Birmingham, Alabama Salary: Open Categories: Academic/Faculty Medical – Research Position Number: 01008 School/College: School of Medicine Job Description: THE OPPORTUNITY The University of Alabama at Birmingham (UAB) Department of Neurology is recruiting an investigator with expertise using human induced pluripotent cells (iPSCs) in Alzheimer’s disease research….

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Bioconductor – hmyriB36

DOI: 10.18129/B9.bioc.hmyriB36     This package is deprecated. It will probably be removed from Bioconductor. Please refer to the package end-of-life guidelines for more information. This package is for version 3.13 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see hmyriB36. YRI…

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Bioconductor Code: metagenomeSeq

metagenomeSeq ============= Statistical analysis for sparse high-throughput sequencing [![Travis-CI Build Status](https://travis-ci.org/HCBravoLab/metagenomeSeq.svg?branch=master)](https://travis-ci.org/HCBravoLab/metagenomeSeq) <a href=”www.bioconductor.org/packages/devel/bioc/html/metagenomeSeq.html#since”><img border=”0″ src=”www.bioconductor.org/shields/years-in-bioc/metagenomeSeq.svg&#8221; title=”How long since the package was first in a released Bioconductor version (or is it in devel only).”></a> <a href=”bioconductor.org/packages/stats/bioc/metagenomeSeq.html”><img border=”0″ src=”www.bioconductor.org/shields/downloads/metagenomeSeq.svg&#8221; title=”Percentile (top 5/20/50% or ‘available’) of downloads over last 6 full months. Comparison…

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Senior Bioinformatics Scientist Job in Minnesota

We are seeking a highly motivated bioinformatician to join the Institute on the Biology of Aging and Metabolism (iBAM) and the Department of Genetics, Cell Biology, and Development at the University of Minnesota. Aging is a natural process throughout an entire life course. Focusing on health and well-being, in…

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Senior Bioinformatics Systems Analyst in Santa Cruz, CA for University of California Santa Cruz

Details Posted: 01-Dec-23 Location: Santa Cruz, California Salary: Open Categories: Information Technology Staff/Administrative Senior Bioinformatics Systems Analyst Location: Santa CruzJob ID: 61781 JOB POSTING NO VISA SPONSORSHIP IS AVAILABLE FOR THIS POSITION.THIS RECRUITMENT WILL REMAIN OPEN UNTIL FILLED. HOW TO APPLY For full consideration, applicants should attach their resume and…

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Assistant Professor: Molecular Biology

Description: The School of Biological Sciences (biology.ucsd.edu/), Department of Molecular Biology, invites applications for two faculty positions in Molecular Biology at the tenure-track Assistant Professor level. Candidates pursuing innovative research in the general area of Computational Molecular Biology are encouraged to apply; applicants with fully dry / computational labs are…

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Bioinformatics Postdoctoral Associate, USA

The Office of Biotechnology, in collaboration with the US Department of Agriculture’s Agricultural Research Service, is seeking applicants for a Bioinformatics Postdoctoral Associate position at the Genome Informatics Facility. This collaborative role, supervised by Andrew Severin at ISU and Crystal Loving at USDA, involves joint projects with the National Animal…

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Bioinformatics Institute, A*STAR hiring Computational Scientist in Singapore

Computational Scientist, Research Data Integration Group, Biomedical Datahub Division, Bioinformatics Institute (A*STAR)   About us Data science is an important component of biomedical and translational research, where data of multiple modalities are being constantly generated at unprecedented scale. The Research Data Integration group in the Biomedical Datahub Division of the…

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Potential use of iPSCs for disease modeling, drug screening, and cell-based therapy for Alzheimer’s disease

Review doi: 10.1186/s11658-023-00504-2. Affiliations Expand Affiliations 1 Department of Cytology and Histology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35116, Egypt. hanymarei@mans.edu.eg. 2 Biomedical Research Center, Qatar University, 2713, Doha, Qatar. 3 Department of Mechanical and Industrial Engineering, College of Engineering, Qatar University, Doha, Qatar. Item in Clipboard Review Hany…

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CYIL vol. 9 (2018) – Page 304

MARTIN ŠOLC CYIL 9 ȍ2018Ȏ In case of mtDNA, however, the situation is rather unique: mitochondria can be considered part of the germline only in oocytes, and not in sperm. In other words, MRT in female embryos arguably represents a germline modification which is transmissible to the next generation, while…

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MSL2 ensures biallelic gene expression in mammals

Materials Animals All of the mice were kept in the animal facility of the Max Planck Institute of Immunobiology and Epigenetics. The mice were maintained under specific-pathogen-free conditions, with 2 to 5 mice housed in individually ventilated cages (Techniplast). The cages were equipped with bedding material, nesting material, a paper…

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Bioinformatics Programmer 2 – 126859

This is a 100% Contract position for one year. This appointment may be extended or converted to career status based on the needs of the department. UC San Diego is a student-centered, research-focused, service-oriented public institution, recognized as one of the top 15 research universities worldwide. The University fosters a…

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Senior Data Scientist (Biostatistics and Bioinformatics Core (BBC)

Senior Data Scientist (Biostatistics and Bioinformatics Core (BBC) University Overview The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey….

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Entry Bioinformatics Professional Cancer Research job with University of Colorado Anschutz Medical Campus

Entry Bioinformatics Professional – Cancer Research – 31970 University Staff Description University of Colorado Anschutz Medical Campus Department: Pediatrics &ndash; Hematology, Oncology, and Bone Marrow Transplant Job Title: Entry Bioinformatics Professional &ndash; Cancer Research Position: # 00817933 &ndash; Requisition: # 31970 Job Summary: The Entry Bioinformatics Professional utilizes applied or…

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DNA methylation change in blood cells of FB and CFS patients

Introduction Fibromyalgia (FM) and Chronic Fatigue Syndrome (CFS) are characterized by chronic pain, fatigue, and weakness. Patients with these symptoms also suffer from sleep abnormalities and report affected cognitive processes such as memory. The diagnosis of these two syndromes is challenging and is based on questionnaires that make the diagnosis…

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ESRP1 controls biogenesis and function of a large abundant multiexon circRNA | Nucleic Acids Research

Abstract While the majority of circRNAs are formed from infrequent back-splicing of exons from protein coding genes, some can be produced at quite high level and in a regulated manner. We describe the regulation, biogenesis and function of circDOCK1(2–27), a large, abundant circular RNA that is highly regulated during epithelial-mesenchymal…

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Research Fellow (Infectious Disease Modelling and Machine Learning for Public Health) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description Research Fellow in Infectious Disease Modelling and Machine Learning for Public Health The National University of Singapore’s Saw Swee School of Public Health (NUS) seeks a dedicated, skilled research fellow to join its multidisciplinary team. This position offers a unique opportunity to participate in innovative research projects on…

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Weill Cornell Medicine to Open Medical Research Center at 1334 York Avenue | Newsroom

NEW YORK (Nov. 28, 2023)—Weill Cornell Medicine is dramatically expanding its campus and research footprint in New York City by securing five floors of 1334 York Ave., the current home of Sotheby’s auction house, the institution announced today. Located one block from Weill Cornell Medicine’s main campus on Manhattan’s Upper…

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SERB Overseas Visiting Doctoral Fellowship

SERB Overseas Visiting Doctoral Fellowship Call for Applications: The application period will be open from 01st November 2023 until 02nd January 2024. Objective: Applications for support to undertake research training during doctoral research in Overseas Universities on a competitive basis are sought from eligible researchers. To build national capacity in…

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Bioconductor – KEGGdzPathwaysGEO

DOI: 10.18129/B9.bioc.KEGGdzPathwaysGEO   KEGG Disease Datasets from GEO Bioconductor version: Release (3.18) This is a collection of 24 data sets for which the phenotype is a disease with a corresponding pathway in the KEGG database.This collection of datasets were used as gold standard in comparing gene set analysis methods by…

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Genome editing approaches with CRISPR/Cas9: the association of NOX4 expression in breast cancer patients and effectiveness evaluation of different strategies of CRISPR/Cas9 to knockout Nox4 in cancer cells | BMC Cancer

A. Bioinformatics analyzes Search strategy and study selection From April to June 2021, we read relevant and related publications in Medline, EMBASE, Web of Science, and Wanfang. The search term “NOX4” have been used. The articles that fit specified criteria were all added at once: (1) Participants were split into…

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Election Lab (pdf) – Course Sidekick

10/16/23, 9:34 AM Election Lab stat20.datahub.berkeley.edu/user/nathen1076225/rstudio/p/4fa63870/ 4/10 sum(variance) 1 60 The variance of X is 60. 5. What is the variance of X? Answer this question by mutating a new column in fd_unif and taking its sum, as in the notes. fd_unif_3 <- mutate (fd_unif_2, expected_value = sum (f_p)) fd_unif_4…

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How DNA Profiling Works

The term “DNA,” once used only by scientists, has become part of our everyday lexicon. It’s almost impossible to not know of DNA profiling, from the court system to genealogy. It’s also nearly impossible to be unaware of the controversy. Now that we can each have a profile that identifies…

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Capturing the ancient origins of humanity

DNA is the unseen constant in our world. Not only do its As, Ts, Cs, and Gs form the basis of all life on earth, but DNA that’s shed from living things will pervade the environment around us and, in some cases, will long outlive us. As a biomaterial, DNA is…

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hg38 RepeatMasker v4.0.7 Dfam_2.0 question

Dear UCSC Genome Browser Support Team:   I hope this message finds you well.   I am writing to you as a postdoctoral researcher from Dr. Xianjun Dong’s Lab at Harvard Medical School. Firstly, I would like to extend my heartfelt gratitude for your significant efforts in developing the human…

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Bioconductor – ind1KG

    This package is for version 2.13 of Bioconductor; for the stable, up-to-date release version, see ind1KG. Data from 1000 Genomes, NA19240 (female) chr6 excerpt Bioconductor version: 2.13 Elements of samtools/bioc workflow for dealing with personal sequence focusing on identification and interpretation of rare variants Author: VJ Carey <stvjc…

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Postdoctoral Researcher in Alzheimer’s disease Genetics, Multi-Omics, and Imaging Biomarkers, St Louis, MO, USA

Location: Department of Neurology, NeuroGenomics and Informatics Center, Washington University in St. Louis Description The Washington University School of Medicine, Department of Neurology, has an opening for a post- doctoral research associate to join the Belloy lab in the NeuroGenomics and Informatics Center (NGI). The successful candidate will be involved…

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Bioconductor – gDNAx

DOI: 10.18129/B9.bioc.gDNAx   Diagnostics for assessing genomic DNA contamination in RNA-seq data Bioconductor version: Release (3.18) Provides diagnostics for assessing genomic DNA contamination in RNA-seq data, as well as plots representing these diagnostics. Moreover, the package can be used to get an insight into the strand library protocol used and,…

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“DNA Methylation, Chromatin Structure and Expression of Maize Ribosomal” by Eldon Ralph Jupe

Document Type Dissertation Degree Name Doctor of Philosophy (PhD) First Advisor Elizabeth A. Zimmer Abstract The restriction endonuclease HpaII was utilized to examine ribosomal RNA gene (rDNA) methylation in maize and teosinte leaf DNA. Much of the rDNA was inaccessible to HpaII cleavage indicating that these repeat units were completely…

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Advances in structure-guided mechanisms impacting on the cGAS-STING innate immune pathway

doi: 10.1016/bs.ai.2023.08.001. Epub 2023 Sep 12. Affiliations Expand Affiliations 1 College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China. 2 College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China; School of Biomedical Engineering, Hubei University of Medicine, Shiyan, Hubei, P.R. China. 3 Structural Biology Program, Memorial Sloan-Kettering Cancer…

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Evaluating 17 methods incorporating biological function with GWAS summary statistics to accelerate discovery demonstrates a tradeoff between high sensitivity and high positive predictive value

Method selection We reviewed the published literature through February 2020 to identify methods that met the following criteria: i. Descriptively categorized as (a) annotation-based; (b) pleiotropy-based; or (c) eQTL-based. ii. Utilized GWAS summary statistics, as opposed to individual-level genotype data. iii. Implemented using freely-available software or packages. iv. Provided either…

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Bioconductor – RdbiPgSQL

PostgreSQL access Bioconductor version: 2.5 Provides methods for accessing data stored in PostgreSQL tables. Code written by Timothy H. Keitt and modified by Jianhua Zhang Author: Timothy H. Keitt <thk at users.sourceforge.net> Maintainer: Jianhua Zhang <jzhang at jimmy.harvard.edu> To install this package, start R and enter: source(“http://bioconductor.org/biocLite.R”) biocLite(“RdbiPgSQL”) To cite…

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Post-Doctoral Associate – Bioinformatics & Computational Biology Job in Minnesota

Required Qualifications: • A PhD degree in related field (Bioinformatics, Computer Science, Statistics, etc.) obtained in the last 1~2 years.• Strong quantitative data analysis background (machine learning, biostatistics, etc.) and/or computational genomics/genetics experiences (spatial transcriptomics, single-cell sequencing, high-throughput omics sequencing data analysis, TWAS/GWAS, etc.) or other relevant areas.• Strong…

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Pan-Cancer Analysis and Validation of Opioid-Related Receptors Reveals

Introduction The potential role of opioids used in oncology patients has been controversial. Epidemiological and retrospective studies have demonstrated that lower opioid doses and regional anesthesia (epidural, intrathecal, or paravertebral) for breast,1 colon,2 or melanoma3 are linked to lower rates of cancer recurrence, while general anesthesia with high opioid doses…

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Bioconductor – limma

Linear Models for Microarray Data Bioconductor version: 2.5 Data analysis, linear models and differential expression for microarray data. Author: Gordon Smyth with contributions from Matthew Ritchie, Jeremy Silver, James Wettenhall, Natalie Thorne, Mette Langaas, Egil Ferkingstad, Marcus Davy, Francois Pepin, Dongseok Choi, Di Wu, Alicia Oshlack, Carolyn de Graaf, Yifang…

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Bioconductor – RankProd

Rank Product method for identifying differentially expressed genes with application in meta-analysis Bioconductor version: 2.5 Non-paramteric method for identifying differentially expressed (up- or down- regulated )genes based on the estimated percentage of false predictions (pfp).The method can combine data sets from different origins (meta-analysis)to increase the power of the identification….

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Analysis of nucleoporin 107 overexpression

Introduction Lung cancer is one of the most common types of cancer worldwide and the leading cause of cancer death.1 The main category of lung cancer is non-small cell lung cancer, accounting for about 85%, and lung adenocarcinoma, as a kind of non-small cell lung cancer, is the most frequently…

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Bioinformatics Scientist – Madison, Wisconsin, United States

Job Summary: The Bioinformatics Scientist will develop, adapt, and implement computational and bioinformatics pipelines for established and novel approaches, depending on the current demands of the service. The Bioinformatics Scientist will be responsible for project management, data delivery, and communication of results to clients as required. As we are a…

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Herpes Zoster Pipeline Analysis Demonstrates Novel 18+

Herpes Zoster Pipeline DelveInsight’s, “Herpes Zoster Pipeline Insight 2023,” report provides comprehensive insights about 18+ companies and 20+ pipeline drugs in the Herpes Zoster pipeline landscape. It covers the Herpes Zoster pipeline drug profiles, including Herpes Zoster clinical trials and nonclinical stage products. It also covers the therapeutics assessment by…

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Postdoctoral Research Associate – Protein Bioinformatics job with Virginia Commonwealth University

The Computer Science Department of the College of Engineering seeks culturally and professionally diverse candidates to apply for the Postdoctoral Research Associate – Protein Bioinformatics position. Since its inception in 1996, the Virginia Commonwealth University College of Engineering has brought innovative, real-world engineering education to Central Virginia. Comprised of five…

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ARFID Genes and Environment (ARFID-GEN): study protocol | BMC Psychiatry

Dinkler L, Bryant-Waugh R. Assessment of avoidant restrictive food intake disorder, pica and rumination disorder: interview and questionnaire measures. Curr Opin Psychiatry. 2021;34(6):532–42. Article  Google Scholar  American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (5th ed.). Arlington, VA: American Psychiatric Publishing; 2013. Thomas JJ, Lawson EA, Micali N, Misra…

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Tenure-Track Assistant Professor Positions job with Vanderbilt University

The Center for Applied Artificial Intelligence in Protein Dynamics (CAAPD), the departments of Molecular Physiology and Biophysics, and Pharmacology within the School of Medicine Basic Sciences at Vanderbilt University invite applications for tenure-track Assistant Professor positions in the general areas of large language models, generative artificial intelligence (AI) and other…

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