Tag: EMBL-EBI

Ontology Development Kit Looks to Harmonize, Streamline Management of Biomedical Semantics

CHICAGO – Nearly seven years after it first appeared online as a beta release, the Ontology Development Kit (ODK) has matured into an open-source software package used by the developers and keepers of dozens of biomedical ontologies. The ODK is meant to implement the principles of the Open Biological and…

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New Algorithms That Harnessed Protein-folding Power in 2022

Big pharma companies have been researching protein folding for a long time now. Discoveries and innovations in the field can revolutionise the development of drug and other biological advancement. Recently, the development of the COVID-19 vaccine was also supported by tackling this issue.  Protein folding prediction process involves a combination…

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Postdoctoral Fellow at European Molecular Biology Laboratory (EMBL)

About the team/job Cell plasticity is considered a key hallmark of metastatic cells and cancer therapy resistance by enabling cell adaptation to adverse conditions. Molecular and cellular mechanisms underlying cell plasticity are still poorly understood and a precise description of cell plasticity remains to reach consensus, mainly due to a…

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Bioinformatics tools and data retrieval

The Job Dispatcher service at the EMBL-EBI provides access to various sequence analysis tools and a database retrieval system (Dbfetch). This virtual course is split into two sessions running over two days.  During the first session, you will learn how to access and use our sequence…

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Empathy List Archives

Dear colleagues, Data on sequence level mapping through the SIFTS process www.ebi.ac.uk/pdbe/docs/sifts/ can now be retrieved directly from updated mmCIF files, available on PDBe entry pages. These files now contain residue-level mapping between UniProt and PDB entries, including coordinate numbering for UniProt accessions and mapping to a host of other…

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How to interpret AlphaFold structures

This webinar will introduce AlphaFold system for prediction and interpretation of protein structures. This webinar is designed for experimental biologists who wish to understand the strengths and limitations of AlphaFold and use the models to guide their experimental studies. In this webinar we will provide an overview for the AlphaFold…

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A global collaboration to map the whole human brain

Baylor College of Medicine researchers in the Tolias Lab and the Xiaolong Jiang Lab are part of a global collaborative led by the Allen Institute to map the whole human brain. In what is being called the brain equivalent of the Human Genome Project, this initiative will map 200 billion cells in the human brain by…

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Single-cell atlas of human liver development reveals pathways directing hepatic cell fates

doi: 10.1038/s41556-022-00989-7. Online ahead of print. Brandon T Wesley #  1   2 , Alexander D B Ross #  1   2   3 , Daniele Muraro  1   2   4 , Zhichao Miao  4   5 , Sarah Saxton  6   7 , Rute A Tomaz  1   2 , Carola M Morell  1   2…

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biomedical research: A database of 200 million-plus protein shapes is hypercharging biomedical research

On July 28, DeepMind, an artificial intelligence (AI) subsidiary of Alphabet, Google’s parent company, published a free, online database of the likely shapes of more than 200 million proteins known to science. This has set off a virtual carnival of biomedical research, which will transform healthcare as well as research…

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Can AlphaFold be used?MIT new research: not much better than random guessing, still needs to continue to improve

After AlphaGo defeated Ke Jie, the world’s No. 1 Go player in 2017, AlphaFold 2 was born in 2020, making artificial intelligence (AI) successful again. 2 years later, what about AlphaFold today? In July this year, DeepMind and EMBL-EBI used AlphaFold to predict almost all known proteins on the earth,…

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AI Continues To Build The Foundation For A Remarkable Future In Biology

Black_Kira By Christopher Gannatti July 28, 2022, was a historic day in both biology and artificial intelligence (AI). DeepMind, an Alphabet-owned (GOOG) (GOOGL) AI research firm, made the structural data on more than 200 million proteins from its AlphaFold tool freely available. This represents data on roughly 1 million species…

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UK Biobank Copy Number-Based GWAS Discovers New Associations With Human Traits

NEW YORK – A new set of analytical tools is making it possible to systematically search for links between copy number variants and complex human traits or conditions, according to a study by a pair of investigators at the European Molecular Biology Laboratory’s European Bioinformatics Institute. “[W]e present a robust…

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DeepMind has predicted the shape of every protein known to science. How excited should we be?

It doesn’t have much photogenic appeal or the glamour of seeing back in time, but a new development in computational biochemistry has been hailed as a discovery as important as the images of distant galaxies recently seen through the James Webb Space Telescope. Researchers at DeepMind—the AI company owned by…

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How AlphaFold can realize AI’s full potential in structural biology

Tomorrow’s AI applications will not happen without research being shared openly in repositories such as that maintained by the European Molecular Biology Laboratory’s European Bioinformatics Institute near Cambridge, UK.Credit: Edmund Sumner/View Pictures/Universal Images Group/Getty “I wake up and type AlphaFold into Twitter.” John Jumper couldn’t hold back his excitement. He…

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EnWik > Expasy

Expasy is an online bioinformatics resource operated by the SIB Swiss Institute of Bioinformatics. It is an extensible and integrative portal which provides access to over 160 databases and software tools and supports a range of life science and clinical research areas, from genomics, proteomics and structural biology, to evolution…

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DeepMind research cracks structure of almost every known protein

Enlarge / An image released by the EMBL’s European Bioinformatics Institute showing the structure of a human protein that was modeled by the AlphaFold computer program. EMBL-EBI/AFP/Getty Images Artificial intelligence has surpassed the limits of scientific knowledge by predicting the shape of almost every known protein, a breakthrough that will…

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DeepMind just uncovered the 3D structure of almost every protein known to science

Researchers have deciphered the three-dimensional structures of almost every protein known to science, which could lead to major advances in a wide range of research areas including the treatment of diseases, sustainability and food insecurity. The findings were announced on Thursday by artificial intelligence (AI) technology company DeepMind, which said…

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AI predicts shape of nearly every known protein

The structure of the vitellogenin protein — a precursor of egg yolk — as predicted by the AlphaFold tool.Credit: DeepMind From today, determining the 3D shape of almost any protein known to science will be as simple as typing in a Google search. Researchers have used AlphaFold — the revolutionary…

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[ccp4bb] Vacancy for EMDB Team Leader (EMBL Faculty position)

Dear colleagues, EMBL-EBI is looking to recruit a new Team Leader (EMBL Faculty position) to take charge of the Electron Microscopy Data Bank (EMDB; emdb-empiar.org), one of the three core archives of the Worldwide Protein Data Bank organisation (wwPDB; wwpdb.org). In the past two years, EMDB has doubled in size…

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Uncharted genetic territory offers insight into human-specific proteins

When researchers working on the Human Genome Project completely mapped the genetic blueprint of humans in 2001, they were surprised to find only around 20,000 genes that produce proteins. Could it be that humans have only about twice as many genes as a common fly? Scientists had expected considerably more….

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Alpha Fold Working

AlphaFold: The making of a scientific breakthrough The inside story of the DeepMind team of scientists and engineers who created AlphaFold, an AI system that is recognised as a solution to “protein folding”, a grand scientific challenge for more than 50…

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Senior Software Developer (commencing immediately) at European Molecular Biology Laboratory (EMBL)

Contract Type: Staff Member Location: EMBL-EBI, Hinxton near Cambridge, UK Job Function: Senior Technical Officer (gr. 6-8) Contract Duration-Length of Time (years/months): 1 year (until grant-end date of 30/10/2023) Contract Duration-Is this renewable to 9 years?: No Advertised Grade-Grading: Grade 6 (monthly salary starting at £3,143.06 after tax plus benefits) About the team/job We are seeking…

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Supporting African BioGenome Project to build bioinformatics capacity

The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa AfricaBP and EMBL MoU. Credit: Karen Arnott/EMBL-EBI The African BioGenome Project (AfricaBP) is an African-led effort to sequence the genomes of all species indigenous to the…

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Job availability: Outreach & Public Engagement Officer

The EMBL is looking to recruit an enthusiastic, highly motivated Outreach & Public Engagement Officer to join the European Learning Laboratory for Life Sciences (ELLS) Team in Heidelberg, Germany. About the role You will develop and deliver a programme of engagement activities that supports EMBL’s scientific programme, with a special…

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Impact of DNA mutations on lifelong blood cell production uncovered — ScienceDaily

New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life. Scientists at the Wellcome Sanger Institute, the Cambridge Stem Cell Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI) and collaborators show how these changes relate to ageing and the development of age-related diseases, including…

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An introduction to EMBL-EBI resources

The EMBL-EBI is the home of the world’s most comprehensive range of freely available molecular databases and resources. Our resources help researchers share and analyse data and perform complex queries in many different ways. Join us for a tour of the core data resources at EMBL-EBI. Who is this…

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Database Administrator at European Molecular Biology Laboratory (EMBL)

About the team/job In this role you will join an established Database team of database administrators in order to support the ongoing database operations. The main duties for this post are: DBA of MySQL and MongoDB.The Database Team provides day-to-day Database Administration support , database performance tuning and query optimization…

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Predicted complexes from ModelArchive now on PDBe-KB pages

High-quality, predicted protein complexes, generated using RoseTTAFold and AlphaFold, are now available in ModelArchive and accessible through the 3D-Beacons Network. These predicted complexes are also integrated into the PDBe-KB aggregated views of proteins. High-quality, predicted protein complexes, generated using RoseTTAFold and AlphaFold, are now available in ModelArchive and accessible through…

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Nature Depth: Where will this revolutionary technology go when artificial intelligence predicts protein structure?

▎ WuXi AppTec content team editor Last July, DeepMind published a study in the journal Nature on artificial intelligence (AI) systems AlphaFold predicting the three-dimensional structure of proteins based on amino acid sequences. The researchers also released the source code of the AI system, making this technology available to scientists…

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Euro-BioImaging Bio-Hub – FAIR Image Data Steward at European Molecular Biology Laboratory (EMBL)

About the team/job Euro-BioImaging ERIC (www.eurobioimaging.eu) is a leading pan-European research infrastructure that provides the research community open access to cutting-edge imaging services. The Euro-BioImaging Bio-Hub hosted by European Molecular Biology Laboratory (EMBL) is looking for a highly motivated FAIR Image Data Steward to develop general guidelines and technically support…

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Scientific Database Curator at European Molecular Biology Laboratory (EMBL)

About the team/job Metabolomics is the study of small molecule metabolites in the metabolome, which is the complete set of metabolites in a biological sample. By studying these metabolites, we can observe changes in cellular networks and biochemical pathways. This allows us to detect disease states and their progression, monitor…

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Bioinformatician/Scientific Programmer job with EMBL

We seek to recruit a structural bioinformatician who is interested in working on the intersection of bioinformatics and cheminformatics. The post holder will join the Velankar team at EMBL-EBI on a 2-year collaborative project between PDBe, ChEMBL and CCDC. They will contribute to improving data processing pipelines to increase the…

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EIROforum to Host Conference on Grand Challenges in AI and Data Science

March 30, 2022 — Artificial intelligence (AI) and machine learning (ML) are pushing scientific research into new domains, providing new opportunities to answer the complex societal and economic challenges facing our societies. From understanding the universe to tracking how viruses infect humans, producing large-scale scientific research requires increasingly innovative AI…

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Ontologies for biocuration | EMBL-EBI Training

This webinar, part of the biocuration series, will introduce the concept of an ontology, a type of controlled vocabulary that encompasses relationships between entities, and will cover why ontologies are useful for describing biological data and biology. The webinar will also discuss the role of biocurators and the relevance of…

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Genomic sequencing aids the global tuberculosis fight

Total number of isolates for each drug by sensitivity. Each drug is represented by a colored circle weighted by the prevalence of phenotypic resistance to that drug. The center of each circle shows the intersection between values on the x-axis and y-axis. Group 1 = associated with resistance. Group 2…

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IntAct | EMBL-EBI Training

Feedback and help Who is this course for? This course is for anyone who would like to study protein-protein interactions. An undergraduate degree in a life science subject, or some background knowledge in protein composition and techniques for studying protein–protein interactions, would be an advantage. To…

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EMBL-EBI Workshop: Network Analysis with Cytoscape and PSICQUIC

This module provides an introduction to the theory and concepts of network analysis. Attendees will learn how to construct protein-protein interaction networks and subsequently use these to analyse large-scale datasets generated these to by techniques such as RNA-Seq or mass-spec proteomics. The course will focus on giving attendees hands-on experience…

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Safeguarding African biodiversity through genomics

The African BioGenome Project aims to safeguard biodiversity and build bioinformatics capacity across Africa African biodiversity. Credit: Karen Arnott/EMBL The African BioGenome Project (AfricaBP) is an Africa-led effort to sequence the genomes of plants, animals, fungi, and protists that are native to the continent of Africa. There is an urgent…

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Programming skills in biocuration | EMBL-EBI Training

This webinar will be the first of our series of webinars on the topic of biocuration and discuss programming skills that can be beneficial in biocuration, as well as provide advice on how to acquire them. In an ELIXIR survey in 2019 which aimed at identifying training needs…

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AI revolutions in biology: Opinions on Alphafold from Instruct-NL

Anastassis Perrakis and Titia Sixma of Instruct-NL explore the role that the new AlphaFold AI system has in the world of structural biology. The paper, published in EMBO Reports, outlines the problems that have been facing computerised protein prediction models since their inception nearly 40 years ago, and assesses the…

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Ensembl | EMBL-EBI Training

Feedback and help Who is this course for? A knowledge of some genomics is required, and some bioinformatics knowledge would be useful but is not essential.  What will I achieve? By the end of the course you will be able to: Explain what Ensembl is and where the data…

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Google Researchers Use Machine Learning Approach To Annotate Protein Domains

Source: www.nature.com/articles/s41587-021-01179-w.epdf Proteins play an important part in the construction and function of all living organisms. Each protein is made up of a chain of amino acid building blocks. Much like an image might have numerous things, a protein can have multiple components, known as protein domains. Researchers have been…

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Executive Assistant to the Associate Directors of EMBL-EBI job with EMBL

The Executive Assistant performs a wide variety of complex and confidential duties. The Executive Assistant uses initiative, tact, judgement, confidentiality as well as strong interpersonal and organisational skills to support the two Associate Directors of EMBL-EBI. In this challenging yet rewarding role you will build on your considerable experience providing…

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Learning from Deep Learning: inspirational story behind AlphaFold

DeepMind Chief Executive visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research A delegation from DeepMind visited EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research (John Jumper 2nd from left, Edith Heard 6th from left, Demis…

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Machine Learning Developer job with EMBL

We are seeking a Machine Learning Developer to build tools that use a combination of text mining methods and Europe PMC services to support database curation. The role will be based in the Literature Services Team at EMBL-EBI Europe PMC is the largest open access database of life science research…

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Confident chemistry | Scientific Computing World

OpenEye Scientific develops and offers large-scale molecular modelling applications and toolkits, primarily aimed at drug discovery and design. ‘Although our tools are used by a wider industrial sector, from large pharma and small biotechs, through to agrochemicals and materials scientists,’  commented Ashutosh Jogalekar, associate director – applications science at  OpenEye Scientific. OpenEye…

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Genomics Beyond Health Care: Future Uses and Considerations of Genome Science

A major new report, Genomics Beyond Health, released today by the Government Office for Science, explores how genomics could play a role in our lives in the future, from sports to education and the fight against crime. Until now, genomics has been used primarily in healthcare and medical research where…

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Bioinformatician job with EMBL | 1401746299

Are you creative, curious, and ambitious and like to tackle challenging biological data analysis problems? We have an exciting opportunity for a bioinformatician interested in structural biological data and functional annotations to work within the Protein Data Bank in Europe Team (PDBe) at the European Bioinformatics Institute (EMBL-EBI). In this…

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Proteomics | EMBL-EBI Training

Feedback and help Who is this course for? An undergraduate degree in a life science subject or some background knowledge on the composition of proteins, would be an advantage. What will I achieve? By the end of the course you will be able to: Describe what is meant by…

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Researchers identify new bacteria and viruses on human skin

Data representing the diverse range of microbes found in the human skin microbiome. Credit: Karen Arnott/EMBL Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI), the National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI), the NIH National Institute of Arthritis and Musculoskeletal and Skin Diseases, and colleagues have identified…

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Researchers identify new bacteria and viruses in human skin

Data representing a variety of microorganisms found in the human skin microflora. Credits: Karen Arnott / EMBL Researchers and colleagues at EMBL’s European Bioinformatics Institute (EMBL-EBI), National Institutes of Health (NIH) National Institute for Human Genome (NHGRI), NIH National Institute for Arthritis, Musculoskeletal and Skin Diseases are new bacteria and…

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Job Opportunity: HPC Engineer at European Bioinformatics Institute (EMBL-EBI) (Hinxton, UK)

New Job opportunity posted by European Bioinformatics Institute (EMBL-EBI): We are seeking a HPC engineer to join our Compute team within our Technical Services Cluster (TSC), serving an institute of over 800 researchers and technical staff. You will be working closely with members of the department, and more widely with…

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48 Postdoctoral and Academic Positions at The European Molecular Biology Laboratory, Germany

Postdoctoral and Academic Positions at The European Molecular Biology Laboratory (EMBL), a molecular biology research institution, Germany Scientific Officer – Protein Expression and Purification Core Facility Staff Member at EMBL Heidelberg Closes 14 February 2022 |  Grading: Grading: 4, 5 or 6; depending on experience and qualifications (monthly salary starting from 3.1k – 3.8k EUR…

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Postdoc Position in Bioinformatics in Stem Cell Neurobiology

DepartmentDepartment of Histology and Embryology  – Faculty of MedicineDeadline 28 Feb 2022Start date Jully 2022Job type full-timeJob field Science and research Medical Faculty of Masaryk University, Brno, Czech Republic, invites excellent scientists to apply for Postdoc position in Bioinformatics in Stem Cell Neurobiology   Description: The Department of Histology and Embryology is…

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Postdoc Position in Bioinformatics in Stem Cell Neurobiology job with MASARYK UNIVERSITY

Department Department of Histology and Embryology – Faculty of Medicine Deadline 28 Feb 2022 Start date Jully 2022 Job type full-time Job field Science and research Medical Faculty of Masaryk University, Brno, Czech Republic, invites excellent scientists to apply for Postdoc position in Bioinformatics in Stem Cell Neurobiology   Description: The Department of…

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AI-sparked life sciences revolution, greatest scientific achievement of 2021

The revolution that Artificial Intelligence has brought about for the life sciences has been considered by Science magazine the main scientific advance of the year 2021. The prestigious journal highlights the feat carried out by the DeepMind research laboratory, in association with the EMBL European Bioinformatics Institute (EMBL-EBI), which has…

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EMPIAR | EMBL-EBI Training

Feedback and help Who is this course for? This course is aimed at anyone who would like to learn more about EMPIAR. An undergraduate knowledge of a subject related to the life sciences would be an advantage. What will I achieve? By the end of the course you will…

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EBI-EMBL taps the cloud to accelerate biomedical research

Charged with storing and analysing hundreds of petabytes of life sciences research data, the European Bioinformatics Institute (EBI-EMBL) has a ravenous appetite for storage and compute infrastructure. Equipped with a £45m grant from UK Research and Innovation, the organisation recently struck a five-year strategic partnership with Google Cloud to help…

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Scientific Training Lead (Grants Programme) – Hinxton

Training is a core activity across EMBL-EBI, involving almost every part of the organisation and coordinated by a team of ~30 people. The Training Team delivers a world-recognised programme that encompasses courses delivered virtually and face-to-face to a global audience alongside self-paced online learning, up-skilling of trainers and secondments. The…

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Dec 10 | CS Colloquium Series: “Multi-scale Data Integration and Causal Inference for Biological and Medical …

Event listing from University of Pittsburgh: Friday, December 10 from 2:00 PM to 3:00 PM Abstract: The advancement of technologies for high-throughput collection of personal data, including environmental, lifestyle, clinical and biomedical data, has inadvertently transformed biology and medicine. Integrating and co-analyzing these different data streams has become the research…

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Research Support Officer job with EMBL

EMBL’s European Bioinformatics Institute (EMBL-EBI) is seeking a Research Support Officer to assist the Service Team Leaders leading EMBL-EBI’s resources with overall scientific management. The Research Support Officer role will provide an exciting opportunity to develop your skills in a wide range of areas. The nature of the role is…

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Senior Programme Manager – EMBL-EBI Services job with EMBL

EMBL’s European Bioinformatics Institute (EMBL-EBI) is seeking a Senior Programme Manager to lead strategic initiatives and projects to support the effective long-term management and delivery of the EMBL-EBI data services portfolio. These services make a variety of data openly available to support life sciences research, and are accessed millions of…

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A gallery of human RNA polymerases

The Müller group’s research provides the most detailed structural information yet about human RNA polymerase I. Cryo-electron microscopy has significantly improved as a powerful tool, offering scientists greater insight into what this enzyme looks like and how it works in human cells. Credit: Müller group/EMBL Using state-of-the-art technology and techniques,…

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European Bioinformatics Institute | EMBL-EBI hiring Software Engineer in Hinxton, England, United Kingdom

In this role you will analyse data, develop production software, create technical documents, take part in the daily Scrum meeting, as well as communicate with other teams at EMBL-EBI and/or with our international collaboration partners. Scalability will be an important feature of your clear, concise, well tested and documented code….

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EBI selects Google Cloud as strategic partner to accelerate the pace of research

Hosting the world’s most comprehensive set of freely available and up-to-date molecular data resources, EMBL’s European Bioinformatics Institute (EMBL-EBI) has announced it has chosen Google Cloud as a strategic cloud partner. As part of a new, comprehensive, five-year partnership, EMBL-EBI will tap Google Cloud’s innovative technologies and global infrastructure to…

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miRNAs and mRNAs in intestinal ischemia-reperfusion injury

Introduction Intestinal ischemia-reperfusion (II/R) injury is a severe clinical complication common in the Intensive Care Unit (ICU). It is associated with high morbidity and mortality.1 Usually, this problem is followed by various causes, including sepsis, shock, trauma, and so on.2 Intestinal ischemia-reperfusion injury destroys intestinal tissue and impairs the function…

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Improving processing and quality of DNA data for biodiversity research

These datasets reuse the globally comprehensive DNA sequence data that ENA and its partners, the National Centre for Biotechnology Information (NCBI)  and the DNA Data Bank of Japan, maintain in the International Nucleotide Sequence Database Collaboration (INSDC). EMBL-EBI maintains ENA, which supplied the first DNA-derived dataset shared through GBIF in…

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Full Stack Software Developer job with EMBL

An exciting opportunity has been created for a full stack software developer to work on the development of the ChEBI database (www.ebi.ac.uk/chebi/), which contains detailed information on small molecule compounds in biology. ChEBI is a very widely used resource, with a growing user base numbered in the hundreds of thousands…

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deepmind alphafold github

The program handily beat all competitors, in what one . This will allow us to run alphafold only using CPU ( which is what our VM has). From the developers’ original publication: “The provided inference . The AlphaFold method. Found insideThis book constitutes the refereed proceedings of the First International…

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3D-Beacons Network: protein structure data, all in one place

3D-Beacons Network acts as a one-stop shop for protein structures by combining and standardising data from several providers Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome. Image obtained from PDBe A new platform called 3D-Beacons Network brings together experimentally determined and predicted protein structure models and related…

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alphafold colab github

for the third time worked! Found inside – Page iiThe eight-volume set comprising LNCS volumes 9905-9912 constitutes the refereed proceedings of the 14th European Conference on Computer Vision, ECCV 2016, held in Amsterdam, The Netherlands, in October 2016. Please make sure you have a large enough hard drive space, bandwidth…

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ELIXIR Technical Officer (bioinformatician/data scientist) at EMBL-EBI

Job:ELIXIR Technical Officer (bioinformatician/data scientist) at EMBL-EBI 0 ELIXIR is seeking an inquisitive, people-oriented bioinformatician, life scientist or data scientist with wide interest in the multidisciplinary application of their skills to join us as a Technical Officer. ELIXIR is a research infrastructure that works with 23 European countries to help…

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Apply for AlphaFold DB Full-Stack Web Developer in Essex

We are looking for a full-stack web developer interested in structural biological data and predicted structures in the AlphaFold Protein Structure Database (AlphaFold DB) to join the Velankar team at the European Bioinformatics Institute (EMBL-EBI). This is an exciting opportunity to work as part of EMBL and DeepMind’s new partnership…

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Web Developer at European Molecular Biology Laboratory (EMBL)

About the team/job IT Services operates and supports the IT infrastructure and services at EMBL headquarters in Heidelberg and at the laboratory’s sites in Barcelona and Rome. In collaboration with the EMBL-EBI in Cambridge our team is creating and implementing a new web infrastructure for all EMBL websites. We are…

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Community Outreach Officer job with EMBL

We are looking to recruit a Community Outreach Officer for Europe PMC to work within the Literature Services team at the European Bioinformatics Institute (EMBL-EBI). Europe PMC provides free and open access to over 39 million publications (abstracts and full text), preprints and other documents enriched with links to data,…

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Personal chemistry

Philipp Geyer was interested in learning how protein levels in the blood change when a person tries to lose weight. Several years ago, Geyer, then a postdoctoral fellow, and his colleagues in Matthias Mann’s lab at the Max Planck Institute of Biochemistry began to analyze samples from a dieting study,…

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A Closer Look at Type 1 Diabetes Causal Variants

By Allison Proffitt September 7, 2021 | Stephen Rich’s group at the University of Virginia along with John Todd’s team at the University of Oxford, have been tracing the genes responsible for type 1 diabetes for years. In 2009 the team conducted the largest GWAS metanalysis of type 1 diabetes,…

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Ligand GNP bound in PDB entry 7obq ‹ Protein Data Bank in Europe (PDBe) ‹ EMBL-EBI

  The above 2D and 3D (Mol*) views of ligand interactions use quaternary structure derived from the PDB entry. Please note: Some chain IDs in the tooltip are followed by a number in square brackets. This number corresponds to the operation ID (mmCIF ‘oper_expression’) used to transform the chain. The…

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Link between amino acid and a range of common diseases could help predict personal risk – Wellcome Sanger Institute

  Researchers have identified a link between mitochondrial DNA variants, amino acid fMet, and a range of common, late-onset diseases One of the first population-scale studies on how common genetic traits are influenced by variations in the DNA of mitochondria, the powerhouses of human cells, has been completed by scientists…

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Could amino acid finding from Cambridge scientists help predict our personal risk of common diseases?

Inside our cells are mitochondria, which act as their powerhouses – generating about 90 per cent of the energy required for the biochemical reactions required for them to function. This is just one of the vital biological functions of these organelles, which are unique in having their own genetic code….

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Research Scientist / Technical Officer X-ray Imaging at European Molecular Biology Laboratory (EMBL)

About the team/job We are seeking two highly motivated X-ray Imaging Research Scientists/Technical Officers to join EMBL Hamburg. EMBL Hamburg has implemented a full-field X-ray microscope on beamline P14 on the PETRA III synchrotron at DESY (Hamburg, Germany). For recent references, see: Polikarpov et al. (2019) Acta Cryst. D75:975, Geier…

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The association of amino acids with various common illnesses can help predict an individual’s risk

Mitochondria.Credits: Wikipedia Commons One of the first population-scale studies on how common genetic traits are affected by changes in mitochondrial DNA, the driving force of human cells, was the European Molecular Biology Laboratory at the Wellcome Trust Sanger Institute, University of Cambridge, EMBL. Tokoro (EMBL-EBI) and its collaborators. The team…

Continue Reading The association of amino acids with various common illnesses can help predict an individual’s risk

Link between amino acid and a range of common diseases could help predict personal risk

Mitochondria.Credits: Wikipedia Commons One of the first population-scale studies on how common genetic traits are affected by changes in mitochondrial DNA, the driving force of human cells, was the European Molecular Biology Laboratory at the Wellcome Trust Sanger Institute, University of Cambridge, EMBL. Tokoro (EMBL-EBI) and its collaborators. The team…

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HPC Engineer at European Molecular Biology Laboratory (EMBL)

About the team/job We are seeking a HPC engineer to join our Compute team within our Technical Services Cluster (TSC), serving an institute of over 800 researchers and technical staff. You will be working closely with members of the department, and more widely with technical users across EMBL-EBI, playing an…

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Eukaryotic Annotation Team Leader job with EMBL

We are seeking a faculty-level genome scientist to lead the Eukaryotic Annotation Team at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI).  As Team Leader you will have strategic responsibility for gene annotation and comparative genomics in the Ensembl project, and also lead the EMBL contribution to a portfolio…

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Open Science and Research Information Officer (Heidelberg, DE or Hinxton, UK)

Description Open Science and Research Information Officer (Heidelberg, DE or Hinxton, UK) – 2 positions available Location: Heidelberg, Germany Staff Category: Staff Member Contract Duration: 3 years (renewable) Grading: 4, 5 or 6; depending on qualifications and experience Closing Date: 19 September 2021 Reference Number: HD02025 EMBL is looking for…

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Human genomics and translational data (ELIXIR/EMBL-EBI, Cambridge, UK)

Job:Scientific Officer: Human genomics and translational data (ELIXIR/EMBL-EBI, Cambridge, UK) 0 ELIXIR is seeking a Scientific Officer to drive stakeholder engagement, document the landscape and identify key requirements relevant for the continued successful implementation of ELIXIR’s federated infrastructure for access to human genomics and translational data. We want to ensure…

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