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Tag: exceRpt
Did COVID vaccines kill 14X more people than they saved?
Did a study just show that COVID-19 vaccines killed 14x more people than they saved?! Take a look at the viral claim, and find out what the facts really are! Claim : COVID Vaccines Kill 14X More People Than They Saved! People are sharing an article (archive) by The…
r – Clustered standard error bars for two-way bar chart in ggplot
I am looking for help with code for adding clustered standard errors to a two-way bar chart generated using ggplot. All of the packages I find are for regression results. I have data in which 1200 respondents each rated 10 profiles (n=12,000). I want to plot the means (Y) by…
Microsoft Only Cloud Giant ‘Leader’ in AI Governance Research Report — Virtualization Review
News Microsoft Only Cloud Giant ‘Leader’ in AI Governance Research Report Microsoft is the only cloud giant to be named a “Leader” in a new research report covering AI governance. In fact, among the largest general cloud computing platforms, IBM is the only other player covered in the “IDC MarketScape:…
genetics – Trouble with Phenotype File in PLINK GWAS – 0 Individuals with Non-Missing Phenotypes
Problem Description: I am facing an issue while running a Genome-Wide Association Study (GWAS) using PLINK. Despite specifying the phenotype file and confirming the presence of the phenotype column (‘ChildPhenotype’), I consistently receive the error message: “0 individuals have non-missing phenotypes.” I have ensured that the values in the specified…
Rating the Cloud Wars Top 10 CEOs –
With the combined market cap of the Cloud Wars Top 10 companies now exceeding $7 trillion — and take a moment to wrap your noggin around that — it would be easy to assume the CEOs of those world-shaping companies all delivered superb performances in 2023. But is that in…
The Year GenAI Stole the Show
When we look back at this past year’s cybersecurity stories a decade from now, what will we remember most? That is the question that I attempt to answer every December in this annual cyber review. The answer for calendar year 2023 is not even close. Throughout the year, one topic…
Google Unveils New AI Model
As Google launches this new AI model, it is important to remember that AI is a tool. Will Google and the government be able to restrain this tool and use it for good, or will the enemy use this tool for evil? From CNBC. Google is launching what it considers…
Fact-based optimistic news from November
If you are not a subscriber to our free, weekly newsletter with fact-based optimistic news, you really should be! 😊 The most surprising news for me in November was that dementia is not increasing, but decreasing. You hear so much about dementia, and with increased lifespans, it seems reasonable that…
CRISPR-created strawberries that stay firmer and fresher longer could revolutionize fruit industry
The cultivated strawberry (Fragaria × ananassa, Duch.) is one of the Rosaceae family renowned for its flavor and health benefits, making it an important agricultural commodity. However, its soft texture leads to a brief shelf life and consequent economic losses. Current breeding aims to enhance firmness without compromising quality, but…
Bioconductor – ind1KG
This package is for version 2.13 of Bioconductor; for the stable, up-to-date release version, see ind1KG. Data from 1000 Genomes, NA19240 (female) chr6 excerpt Bioconductor version: 2.13 Elements of samtools/bioc workflow for dealing with personal sequence focusing on identification and interpretation of rare variants Author: VJ Carey <stvjc…
CRISPR gene editing tackles yet another health scourge: High cholesterol
For the first time, researchers have produced evidence that gene-editing can cut high cholesterol, a major risk factor for the nation’s leading killer. Preliminary results from a study involving 10 patients born with a genetic condition that causes very high cholesterol found that editing a gene inside the liver can significantly reduce…
Extracting list of identical items from several excel files
Extracting list of identical items from several excel files 0 Hi guys, I have 10 excel files with several columns and rows. The column headers are similar in all file but for the rows some items are similar while others are not. Below is an excerpt for one of the…
Hybrid Immunity Better Than Natural / Vaccine Immunity!
Did an Estonian study just proved that natural immunity is better than vaccine immunity?! Take a look at the viral claims, and find out why hybrid immunity offers even better protection! Claim : Natural Immunity Is Better Than Vaccine Immunity! Anti-vaccine activists are sharing and/or promoting an article by…
Record Store Day Guide To 14 Unreleased & Reissued Jazz Recordings: Brubeck, Evans, Jamal & More
Rather than provide our usual detailed reviews of these never-before-released and/or reissued jazz recordings, we will instead provide a summary of each in alphabetical order by artist. While we see some of the usual suspects such as Bill Evans, Wes Montgomery, Charles Mingus, and Oscar Peterson, we also see Les…
First CRISPR drug: UK approves Casgevy to prevent pain from sickle cell disease and beta thalassemia
The first medical treatment that uses Crispr gene editing was authorized [November 16] by the United Kingdom. The one-time therapy, which will be sold under the brand name Casgevy, is for patients with sickle cell disease and a related blood disorder called beta thalassemia, both of which are inherited. The…
First CRISPR medicine: UK approves Casgevy for sickle cell disease and beta thalassemia
The first medical treatment that uses Crispr gene editing was authorized [November 16] by the United Kingdom. The one-time therapy, which will be sold under the brand name Casgevy, is for patients with sickle cell disease and a related blood disorder called beta thalassemia, both of which are inherited. The…
Are Residual DNA In mRNA Vaccines Dangerous?!
Are residual DNA impurities in mRNA vaccines dangerous, and can they integrate into our DNA?! Take a look at the viral claims, and find out what the facts really are! Claim : Residual DNA In mRNA Vaccines Are Dangerous! Anti-vaccine activists are sharing and/or promoting an article by The…
Ancient pairing: Neanderthals and humans first interbred 250,000 years ago, new analysis shows
Neanderthals and anatomically modern humans initially interbred 250,000 years ago, a date that is far earlier than previously thought, a new study suggests. Until now, Neanderthals and anatomically modern humans (Homo sapiens) were believed to have first interbred earlier than 75,000 years ago, according to a 2016 genetic analysis in the journal Nature….
Breakthrough CRISPR treatment for sickle cell anemia up for FDA approval
On 31 October, external advisers to the US Food and Drug Administration (FDA) will meet to discuss a DNA-altering therapy for sickle-cell disease, a genetic condition that causes red blood cells to become misshapen, which can lead to debilitating pain. The advisers’ discussions are likely to be laser-focused on safety data…
Did EMA Confirm Pfizer Hid SV40 DNA In Vaccine?!
Did the EMA (European Medicines Agency) just confirm that Pfizer hid the presence of SV40 DNA in its mRNA COVID-19 vaccine? Take a look at the viral claim, and find out what the facts really are! Claim : EMA Confirmed Pfizer Hid SV40 DNA In Vaccine! Some people are…
Background mutations: Why CRISPR-edited genes have to work together with thousands of naturally-evolved genes
For tens of thousands of years, evolution shaped tomatoes through natural mutations. Then, humans came along. For centuries, we’ve bred and cherry-picked tomatoes with our preferred traits. Today, CRISPR genome editing allows us to make new crop mutations that improve traits even further. However, individual mutations, whether natural or engineered,…
Google Cloud Debuts Industry-Specific Generative AI for Manufacturing, Healthcare
Connecting two of the hottest trends in the enterprise-tech world, Google Cloud is rolling out industry-specific generative artificial intelligence (GenAI) solutions for healthcare and for manufacturing to help customers not only boost productivity but also transform themselves for the digital age. Claiming that “82% of organizations considering or currently using…
Openapi-generator: How to deal with generated `ApiError`? – help
So we generate a server stub from our OpenAPI spec yaml using openapi-generator. We integrate the generated server code with Axum. Following an excerpt from generating a server of OpenAPI’s pet store example: #[async_trait] impl<C> Api<C> for Server<C> where C: Has<XSpanIdString> + Send + Sync { /// Create a pet…
public databases – Converting VCF format to text for use with PLINK and understanding column mapping
I successfully completed Nature PRS tutorial, which is based on PLINK. Turning to my real data, I downloaded ukb-d-20544_1.vcf.gz. Now I’m facing the problem that I seem to be unable to use it in PLINK or find the correct data format to download at all, and I am a bit…
Filter vcf SNPs by sample GT value
Filter vcf SNPs by sample GT value 1 I have a merged VCF file with multiple samples on joined SNP set, where original genotypes have a 0|0 / 0|1 / 1|0 / 1|1 genotype (GT) and merged are fomatted as 0/0 if SNP was missing (–missing-ref option of bcftools merge)….
False claims recirculate on harmful DNA in Covid-19 vaccines
Scientists have repeatedly refuted the claim that Covid-19 vaccines can alter a person’s genome, but social media posts suggest DNA contamination in the injections could lead to harmful effects such as cancer. This is false; there is no evidence of significant amounts of genetic material in the shots — and…
China’s CRISPR gene-edited silkworms spin fibers 6 times tougher than Kevlar
Scientists in China have synthesized spider silk from genetically modified silkworms, producing fibers six times tougher than the Kevlar used in bulletproof vests. The study, published September 20 in the journal Matter, is the first to successfully produce full-length spider silk proteins using silkworms. The findings demonstrate a technique that could…
Sprinklr expands partnership with Google Cloud to unify customer experience with AI
US-based Sprinklr, a software company operating a unified customer experience management (Unified-CXM) platform for modern enterprises, today said it has integrated the Sprinklr AI+ platform with Google Cloud’s Vertex AI for unified customer experience management. What is Sprinklr AI+? Sprinklr AI+ gives brands unified generative AI capabilities for customer service,…
python – Unexpected error with sign() function in SageMath
I have the following rather strange issue with SageMath (mathematics software system partly based on Python). Perhaps it should be mentioned that the problem seem to be related with some specific SageMath libraries (dealing with permutations and Lie algebras). Here is the part of the code which does not compile…
13 Stories You Need to See
A roundup of the week’s most newsworthy sports industry press releases from PR Newswire, including PepsiCo’s “Unretirement” campaign and LG’s partnership with the Yankees. NEW YORK, Sept. 1, 2023 /PRNewswire/ — With thousands of press releases published each week, it can be difficult to keep up with everything on PR Newswire….
The Lifecycle of Ribosomal RNA in Bacteria
Review In: RNA Damage and Repair. Cham (CH): Springer; 2021 Jul. Chapter 2. Affiliations Expand Affiliations 1 School of Biological and Chemical Sciences, Queen Mary University of London London, UK 2 Corresponding author: c.engl@qmul.ac.uk Free Books & Documents Item in Clipboard Review Maria Grazia Giuliano et al. Free Books & Documents…
PSA Cryptoprocessor driver development examples
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implemented”,”anchor”:”process-for-entry-points-where-auto-generation-is-implemented”,”htmlText”:”Process for Entry Points…
SDCC Lucasfilm Publishing Panel Recap – New High Republic Phase 3 Covers, ‘From A Certain Point of View’ Information, and More
San Diego Comic-Con is now in full swing, and Lucasfilm Publishing held their panel today revealing new details about their upcoming books and comics soon to be released. For those who weren’t in attendance, StarWars.com provided a full summary of the highlights from the panel. Most of the news shared…
Query Regarding Visualization of PBC Behavior in CP2K AIMD Simulation
I hope this email finds you well. I have a query regarding my CP2K AIMD simulation involving a water box with periodic boundary conditions (PBC) in the XY direction. Here is an excerpt from my input file: &CELL ABC 24.4797 24.4797 200.0 ALPHA_BETA_GAMMA…
Notebook spawned in Yarn but killed after timeout – JupyterHub
Hi, I am trying to set up JupyterHub with YarnSpawner against a Hadoop cluster. I’m seeing a peculiar failure in which the notebook is spawned and successfully begins running, at least one activity message is sent back to the Hub (received and logged), but the Hub still times out waiting…
Viewpoint: ‘The true promise of gene-editing isn’t in pitless cherries or vitamin fortified-foods but in the vast potential for treatment and cures of human disease’
I’m not sure we need cherries with no pits, mustard greens that are less bitter or tomatoes with increased levels of gamma-aminobutyric acid. But cassava that doesn’t release cyanide, plants that are more resistant to attack by disease-causing organisms, and cures for genetic disorders such as sickle cell anemia and…
Primaquine Therapy and G6PD and CYP2D6 Genotype – Medical Genetics Summaries
Introduction Primaquine is a potent antimalarial medication indicated for the radical cure of malaria caused by Plasmodium vivax (P. vivax) and Plasmodium ovale (P. ovale) species (1, 2). Malaria is a blood borne infection caused by infection of Plasmodium parasites that is spread by mosquitos. The P. vivax and P….
Spring Data REST: force openapi schema export
When working with SDR, I need that the associated resources are expanded in the returned JSON. I have achieved this by adding @RestResource(exported = false) to the associated resource. For example: @NotNull @RestResource(exported = false) @ManyToOne(fetch = FetchType.EAGER) private Client client; So far so good, as I can read and write to the association without…
Google Cloud Unleashes Generative AI Partnership Blitz
Further demonstrating why it recently moved up to the #2 spot on the Cloud Wars Top 10 rankings, Google Cloud continues to complement its rollout of GenAI products and services by adding Accenture to its aggressive GenAI partnership blitz that includes SAP, Salesforce, and several global SIs. Google Cloud’s willingness…
Rewriting human evolution: Technological breakthroughs have helped us decode ancient DNA. What have we learned so far?
New fossil finds and technological breakthroughs in collecting and decoding ancient DNA are re-writing the history of human evolution, often with shocking and surprising results. As developments continue apace, what could be uncovered next? “Ours, it turns out, is a repeated history of migrations and mixing,” says Cosimo Posth, a…
Expert Advice on CRISPR Design
The following is an excerpt from an E-book that Twist developed for Genetic Engineering News: The Changing Landscape of CRISPR Screening: A guidebook to the latest CRISPR screening methodologies and technologies. You can download the full E-book here. Even for seasoned researchers, designing an sgRNA library can be…
QLoRa, Reprompting, Retrieval Augmented Generation, Triton PyTorch Backend, Google Dialogflow ES in Twilio, PointNet Data Preparation
👋 Hey, “Causal inference is the key to unlocking the true value of data in making informed decisions.” – Judea Pearl, Computer Scientist Inferences of causality allow us to understand cause-and-effect relationships, uncover hidden connections, predict outcomes, and design effective interventions, thereby guiding us in informed decision-making. Without it, we would…
Retrieving allele-specific information for a variant using VEP annotation
Hi all! I annotated a VCF file using VEP and noticed that it reports several variant IDs to each input variant. For example, this is an excerpt of one of the variant lines (I removed the annotation info that is not relevant to the question): 12 25398284 . C A…
Here’s how CRISPR gene editing is already revolutionizing medicine
A number of genetic disorders are caused by a mutation in a single gene. The power (and precision) of CRISPR is allowing scientists to uproot those conditions from the human genome in a single, life-changing treatment. CRISPR therapies for blood disorders, like sickle cell disease and beta thalassemia, were among…
Sample GenBank Record / Visual abstracts made easy with Mind the Graph
This page presents an annotated sample GenBank record (accession number U49845) in its GenBank Flat File format. You can check the corresponding alive record for U49845, and seeexamples of other records the show a range of biological features. SITE SCU49845 5028 bp DNA PLN 21-JUN-1999 DEFINITION Saccharomyces cerevisiae TCP1-beta gene,…
Fear of unintended consequences slows adoption of embryo gene editing
It’s been a little over four years since a five-minute video brought the scientific community to a standstill. In the clip, Chinese scientist Dr He Jiankui claimed he’d created the world’s first genome-edited babies – twin girls called Luna and Nala. Follow the latest news and policy debates on sustainable…
Simplifying Time Series Forecasting: Replicating Monsaraida’s Solution
The M5 Competition, hosted on Kaggle, has recently drawn attention to the effectiveness of gradient-boosting methods for volume forecasts of retail products. In this article, we will focus on the accuracy track of the competition and tackle a time series problem. By replicating one of the top-ranking, yet simplest and…
10 Stories You Need to See
A roundup of the week’s most newsworthy health industry press releases from PR Newswire, including a new study of overdose prevention centers. NEW YORK, May 12, 2023 /PRNewswire/ — With thousands of press releases published each week, it can be difficult to keep up with everything on PR Newswire. To…
9 Stories You Need to See
A roundup of the week’s most newsworthy technology industry press releases from PR Newswire, including AI updates from SAS, IBM, and Autodesk. NEW YORK, May 12, 2023 /PRNewswire/ — With thousands of press releases published each week, it can be difficult to keep up with everything on PR Newswire. To…
New Genome Map Tries To Capture All Human Genetic Variation
An anonymous reader shares an excerpt from MIT Technology Review: Today, researchers announced yet another version of the human genome map, which they say combines the complete DNA of 47 diverse individuals — Africans, Native Americans, and Asians, among other groups — into one giant genetic atlas that they say…
Human Genome Project was completed 20 years ago. Here’s how it has revolutionized science
For the 20-year anniversary of this historic event, we took a look back at the Human Genome Project and its impact. How did it shape science moving forward? Follow the latest news and policy debates on sustainable agriculture, biomedicine, and other ‘disruptive’ innovations. Subscribe to our newsletter. “I think the very…
From Cavendish bananas to Arabica coffee, many favorite foods may succumb to disease and go extinct. CRISPR gene editing offers a solution
Some of our most beloved crops are currently under existential threat. Coffee, cacao, banana, and citrus fall into this unfortunate category. Arabica coffee, for example, is a notoriously finicky crop that requires a certain amount of rainfall and mild temperatures to grow. But weather volatility is forcing some farmers along…
The cost-effectiveness of whole genome sequencing in neurodevelopmental disorders
Study design This study was designed as a retrospective observational study that compared historical data on healthcare costs, diagnostic yield and type of genetic tests between two cohorts of patients referred to the department of Clinical Genetics at the Karolinska University Hospital. One cohort (cohort CMA) represented standard care, with…
2023-04-07 | NDAQ:APDN | Press Release
Applied DNA Sciences, Inc. (NASDAQ: APDN) (the “Company”), a leader in PCR-based DNA technologies, announced that its CertainT® supply chain traceability platform is featured in an article on the home page of the New York Times website today. The article, titled “How A.I. and DNA Are Unlocking the Mysteries of…
Phylogenomic analysis uncovers a 9-year variati…
Your new post is loading… Your new post is loading… Scooped by Ed Rybicki Scoop.it! Scooped by Ed Rybicki Scoop.it! This study has helped elucidate the responses underlying susceptibility to H5N1 influenza in avian species, which will be critical in developing sustainable strategies for future control of HPAI in domestic…
Stocks discussed: (NYSE: NOTE) (NasdaqGS: NVDA)
Vancouver, Kelowna, Delta, BC – March 24, 2023 (Investorideas.com Newswire) Investorideas.com, a global investor news source covering Artificial Intelligence (AI) brings you today’s edition of The AI Eye – watching stock news, deal tracker and advancements in artificial intelligence. Today’s podcast is sponsored by Fintech Company AppTech Payments Corp. (NasdaqCM:APCX)….
bcl-convert demux of flowcell with mixed index lengths
bcl-convert demux of flowcell with mixed index lengths 1 Hi! I am trying to use bcl-convert to demultiplex a flowcell where samples with mixed index lengths were present. The sequencer was run with the read structure 150-10-10-150 and we generated separate samplesheets for the case where samples had 10 b…
autopkgtest regression in stable with latest Java 11
Source: fdroidserver Version: 2.0.3-1 Severity: important Hi, with the latest security update of openjdk-11 in stable (which updated from 11.0.6 to 11.0.8, as we’re following the Java LTS releases), the autopkgtest of fdroidserver fails. This seems caused by the “Disabled SHA-1 Signed JARs (JDK-8269039)” change listed here: www.oracle.com/java/technologies/javase/11-0-17-relnotes.html Full logs can be found at…
No human genome has ever been read in its entirety before. This year, that might change
Before the end of 2023, you should be able to read something remarkable. It will be the story of a single individual, who they are and where they come from – and it will offer hints about what their future holds. It probably won’t be the most entertaining read on…
At-home bohacking using CRISPR to edit DNA? You can do it with a kit
You may know Jo Zayner, a “biohacker” who has been in the vanguard of scientific self-experimentation for years, from their role in Netflix’s 2019 docuseries Unnatural Selection. The series shows Zayner attempting to edit their DNA by injecting themselves with CRISPR, a gene-editing technology. The action inspired a firestorm of criticism. Zayner…
CRISPR gene editing can treat heart disease and repair damaged tissue after a heart attack
Each year, cardiovascular disease (CVD) — also known as heart disease — accounts for about 32% of all deaths around the world. The most common type of heart disease is coronary artery disease, where blood is not able to flow properly to the heart. If blood flow is completely blocked to the heart, this can cause a heart…
CRISPR co-creator: 2023 sees mobilization of gene editing to develop crops that resist climate change, as world food demand rises
Following on the heels of the initial clinical trial results, the first agricultural applications using Crispr have recently entered the market: A US Food and Drug Administration–approved edit to cattle genes re-creates a slick coat that is occasionally found in nature and allows cows to tolerate increasing temperatures; a Crispr-edited…
CRISPR gene editing is in clinical trials to treat sickle cell disease, cancer, HIV/AIDS and some rare inherited diseases. Here’s what we can expect going forward
Examples of Crispr’s promise arrive frequently, as new clinical trials report their results. Most are still at an early stage, but the sheer breadth of diseases targeted, and the mainly positive results so far, mean it is easy to be optimistic about the future of this technique. Follow the latest…
Newborn Genomes Program: Whole genome sequencing for 100,000 UK babies leads to test for 200 disorders
Every year, several thousand children in the UK are affected by rare genetic diseases, but families often endure years of tests and uncertainty before they receive a diagnosis, as symptoms can develop slowly. By the time a diagnosis is confirmed avoidable damage may have been done. … The list of…
Dyadic International : Presentation | MarketScreener
Dyadic International (NASDAQ: DYAI) Next Generation Proteins for World Health C1 Vaccine Technology Presentation Mark Emalfarb, Founder & CEO Vaccine Technology Summit September 15-16, 2022 London UK Safe Harbor Regarding Forward-looking Statements Certain statements contained in this presentation are forward-looking statements within…
Read Blake Crouch’s ‘Upgrade’ With The SciFri Book Club
Welcome to the SciFri Book Club about Upgrade by Blake Crouch. There’s lots of ways to participate: Read the book, listen to our interview with the author, join our online community space, or send a voice message at (646) 767-6532 or on the SciFri VoxPop app. This August, the SciFri Book Club will contemplate the…
Tramadol Therapy and CYP2D6 Genotype – Medical Genetics Summaries
Introduction Tramadol (brand names ConZip, Ultram, UltramER, Odolo) is an analgesic used to treat moderate to severe pain. It is used for a variety of pain conditions, including post-operative pain, cancer pain, and musculoskeletal pain. Tramadol is a centrally acting opioid analgesic with mu-opioid binding activity as well as weak…
Bioconductor – dsQTL
DOI: 10.18129/B9.bioc.dsQTL This package is for version 3.11 of Bioconductor; for the stable, up-to-date release version, see dsQTL. dsQTL, data excerpt from Degner et al. 2012 Nature letter Bioconductor version: 3.11 dsQTL, excerpt from Degner et al. 2012 Nature letter on DNA variants associated with DnaseI hypersensitivity Author:…
Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 1 | MIT 7.01SC Fundamentals of Biology, 24.42 MB, 17:47
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GRCh37 GFF filter transcript isoforms by RefSeq Select tag or longest
GRCh37 GFF filter transcript isoforms by RefSeq Select tag or longest 0 Dear all, I tried to filter the “RefSeq Select” transcript isoforms in the GRCh37.p13 human genome annotation gff (GCF_000001405.25_GRCh37.p13_genomic.gff.gz). Specifically my goal is to retain for each gene a transcript isoform with a tag=RefSeq Select attribute if exists,…