Tag: exceRpt
Expert Advice on CRISPR Design
The following is an excerpt from an E-book that Twist developed for Genetic Engineering News: The Changing Landscape of CRISPR Screening: A guidebook to the latest CRISPR screening methodologies and technologies. You can download the full E-book here. Even for seasoned researchers, designing an sgRNA library can be…
QLoRa, Reprompting, Retrieval Augmented Generation, Triton PyTorch Backend, Google Dialogflow ES in Twilio, PointNet Data Preparation
👋 Hey, “Causal inference is the key to unlocking the true value of data in making informed decisions.” – Judea Pearl, Computer Scientist Inferences of causality allow us to understand cause-and-effect relationships, uncover hidden connections, predict outcomes, and design effective interventions, thereby guiding us in informed decision-making. Without it, we would…
Retrieving allele-specific information for a variant using VEP annotation
Hi all! I annotated a VCF file using VEP and noticed that it reports several variant IDs to each input variant. For example, this is an excerpt of one of the variant lines (I removed the annotation info that is not relevant to the question): 12 25398284 . C A…
Here’s how CRISPR gene editing is already revolutionizing medicine
A number of genetic disorders are caused by a mutation in a single gene. The power (and precision) of CRISPR is allowing scientists to uproot those conditions from the human genome in a single, life-changing treatment. CRISPR therapies for blood disorders, like sickle cell disease and beta thalassemia, were among…
Sample GenBank Record / Visual abstracts made easy with Mind the Graph
This page presents an annotated sample GenBank record (accession number U49845) in its GenBank Flat File format. You can check the corresponding alive record for U49845, and seeexamples of other records the show a range of biological features. SITE SCU49845 5028 bp DNA PLN 21-JUN-1999 DEFINITION Saccharomyces cerevisiae TCP1-beta gene,…
Fear of unintended consequences slows adoption of embryo gene editing
It’s been a little over four years since a five-minute video brought the scientific community to a standstill. In the clip, Chinese scientist Dr He Jiankui claimed he’d created the world’s first genome-edited babies – twin girls called Luna and Nala. Follow the latest news and policy debates on sustainable…
Simplifying Time Series Forecasting: Replicating Monsaraida’s Solution
The M5 Competition, hosted on Kaggle, has recently drawn attention to the effectiveness of gradient-boosting methods for volume forecasts of retail products. In this article, we will focus on the accuracy track of the competition and tackle a time series problem. By replicating one of the top-ranking, yet simplest and…
10 Stories You Need to See
A roundup of the week’s most newsworthy health industry press releases from PR Newswire, including a new study of overdose prevention centers. NEW YORK, May 12, 2023 /PRNewswire/ — With thousands of press releases published each week, it can be difficult to keep up with everything on PR Newswire. To…
9 Stories You Need to See
A roundup of the week’s most newsworthy technology industry press releases from PR Newswire, including AI updates from SAS, IBM, and Autodesk. NEW YORK, May 12, 2023 /PRNewswire/ — With thousands of press releases published each week, it can be difficult to keep up with everything on PR Newswire. To…
New Genome Map Tries To Capture All Human Genetic Variation
An anonymous reader shares an excerpt from MIT Technology Review: Today, researchers announced yet another version of the human genome map, which they say combines the complete DNA of 47 diverse individuals — Africans, Native Americans, and Asians, among other groups — into one giant genetic atlas that they say…
Human Genome Project was completed 20 years ago. Here’s how it has revolutionized science
For the 20-year anniversary of this historic event, we took a look back at the Human Genome Project and its impact. How did it shape science moving forward? Follow the latest news and policy debates on sustainable agriculture, biomedicine, and other ‘disruptive’ innovations. Subscribe to our newsletter. “I think the very…
From Cavendish bananas to Arabica coffee, many favorite foods may succumb to disease and go extinct. CRISPR gene editing offers a solution
Some of our most beloved crops are currently under existential threat. Coffee, cacao, banana, and citrus fall into this unfortunate category. Arabica coffee, for example, is a notoriously finicky crop that requires a certain amount of rainfall and mild temperatures to grow. But weather volatility is forcing some farmers along…
The cost-effectiveness of whole genome sequencing in neurodevelopmental disorders
Study design This study was designed as a retrospective observational study that compared historical data on healthcare costs, diagnostic yield and type of genetic tests between two cohorts of patients referred to the department of Clinical Genetics at the Karolinska University Hospital. One cohort (cohort CMA) represented standard care, with…
2023-04-07 | NDAQ:APDN | Press Release
Applied DNA Sciences, Inc. (NASDAQ: APDN) (the “Company”), a leader in PCR-based DNA technologies, announced that its CertainT® supply chain traceability platform is featured in an article on the home page of the New York Times website today. The article, titled “How A.I. and DNA Are Unlocking the Mysteries of…
Phylogenomic analysis uncovers a 9-year variati…
Your new post is loading… Your new post is loading… Scooped by Ed Rybicki Scoop.it! Scooped by Ed Rybicki Scoop.it! This study has helped elucidate the responses underlying susceptibility to H5N1 influenza in avian species, which will be critical in developing sustainable strategies for future control of HPAI in domestic…
Stocks discussed: (NYSE: NOTE) (NasdaqGS: NVDA)
Vancouver, Kelowna, Delta, BC – March 24, 2023 (Investorideas.com Newswire) Investorideas.com, a global investor news source covering Artificial Intelligence (AI) brings you today’s edition of The AI Eye – watching stock news, deal tracker and advancements in artificial intelligence. Today’s podcast is sponsored by Fintech Company AppTech Payments Corp. (NasdaqCM:APCX)….
bcl-convert demux of flowcell with mixed index lengths
bcl-convert demux of flowcell with mixed index lengths 1 Hi! I am trying to use bcl-convert to demultiplex a flowcell where samples with mixed index lengths were present. The sequencer was run with the read structure 150-10-10-150 and we generated separate samplesheets for the case where samples had 10 b…
autopkgtest regression in stable with latest Java 11
Source: fdroidserver Version: 2.0.3-1 Severity: important Hi, with the latest security update of openjdk-11 in stable (which updated from 11.0.6 to 11.0.8, as we’re following the Java LTS releases), the autopkgtest of fdroidserver fails. This seems caused by the “Disabled SHA-1 Signed JARs (JDK-8269039)” change listed here: www.oracle.com/java/technologies/javase/11-0-17-relnotes.html Full logs can be found at…
No human genome has ever been read in its entirety before. This year, that might change
Before the end of 2023, you should be able to read something remarkable. It will be the story of a single individual, who they are and where they come from – and it will offer hints about what their future holds. It probably won’t be the most entertaining read on…
At-home bohacking using CRISPR to edit DNA? You can do it with a kit
You may know Jo Zayner, a “biohacker” who has been in the vanguard of scientific self-experimentation for years, from their role in Netflix’s 2019 docuseries Unnatural Selection. The series shows Zayner attempting to edit their DNA by injecting themselves with CRISPR, a gene-editing technology. The action inspired a firestorm of criticism. Zayner…
CRISPR gene editing can treat heart disease and repair damaged tissue after a heart attack
Each year, cardiovascular disease (CVD) — also known as heart disease — accounts for about 32% of all deaths around the world. The most common type of heart disease is coronary artery disease, where blood is not able to flow properly to the heart. If blood flow is completely blocked to the heart, this can cause a heart…
CRISPR co-creator: 2023 sees mobilization of gene editing to develop crops that resist climate change, as world food demand rises
Following on the heels of the initial clinical trial results, the first agricultural applications using Crispr have recently entered the market: A US Food and Drug Administration–approved edit to cattle genes re-creates a slick coat that is occasionally found in nature and allows cows to tolerate increasing temperatures; a Crispr-edited…
CRISPR gene editing is in clinical trials to treat sickle cell disease, cancer, HIV/AIDS and some rare inherited diseases. Here’s what we can expect going forward
Examples of Crispr’s promise arrive frequently, as new clinical trials report their results. Most are still at an early stage, but the sheer breadth of diseases targeted, and the mainly positive results so far, mean it is easy to be optimistic about the future of this technique. Follow the latest…
Newborn Genomes Program: Whole genome sequencing for 100,000 UK babies leads to test for 200 disorders
Every year, several thousand children in the UK are affected by rare genetic diseases, but families often endure years of tests and uncertainty before they receive a diagnosis, as symptoms can develop slowly. By the time a diagnosis is confirmed avoidable damage may have been done. … The list of…
Dyadic International : Presentation | MarketScreener
Dyadic International (NASDAQ: DYAI) Next Generation Proteins for World Health C1 Vaccine Technology Presentation Mark Emalfarb, Founder & CEO Vaccine Technology Summit September 15-16, 2022 London UK Safe Harbor Regarding Forward-looking Statements Certain statements contained in this presentation are forward-looking statements within…
Read Blake Crouch’s ‘Upgrade’ With The SciFri Book Club
Welcome to the SciFri Book Club about Upgrade by Blake Crouch. There’s lots of ways to participate: Read the book, listen to our interview with the author, join our online community space, or send a voice message at (646) 767-6532 or on the SciFri VoxPop app. This August, the SciFri Book Club will contemplate the…
Tramadol Therapy and CYP2D6 Genotype – Medical Genetics Summaries
Introduction Tramadol (brand names ConZip, Ultram, UltramER, Odolo) is an analgesic used to treat moderate to severe pain. It is used for a variety of pain conditions, including post-operative pain, cancer pain, and musculoskeletal pain. Tramadol is a centrally acting opioid analgesic with mu-opioid binding activity as well as weak…
Bioconductor – dsQTL
DOI: 10.18129/B9.bioc.dsQTL This package is for version 3.11 of Bioconductor; for the stable, up-to-date release version, see dsQTL. dsQTL, data excerpt from Degner et al. 2012 Nature letter Bioconductor version: 3.11 dsQTL, excerpt from Degner et al. 2012 Nature letter on DNA variants associated with DnaseI hypersensitivity Author:…
Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 1 | MIT 7.01SC Fundamentals of Biology, 24.42 MB, 17:47
Your browser does not support the audio element Download lagu Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 1 | MIT 7.01SC Fundamentals of Biology You can download MP3 for free at Free MP3 & Lyrics Download. Song details Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 1 | MIT 7.01SC Fundamentals…
GRCh37 GFF filter transcript isoforms by RefSeq Select tag or longest
GRCh37 GFF filter transcript isoforms by RefSeq Select tag or longest 0 Dear all, I tried to filter the “RefSeq Select” transcript isoforms in the GRCh37.p13 human genome annotation gff (GCF_000001405.25_GRCh37.p13_genomic.gff.gz). Specifically my goal is to retain for each gene a transcript isoform with a tag=RefSeq Select attribute if exists,…