Tag: FAIR

High school student learning ML with a short-term goal of placing top on Kaggle? : learnmachinelearning

I’m an 11th grade student who’s fairly interested in machine learning and the AI industry. I have coding experience but haven’t learned ML yet. My short term goal is to place high on a Kaggle competition because there aren’t that many tangible goals I can place as a high school…

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Functioning induced liver cells from skin tissue

Figure 1. Urea metabolism is impaired in patient-derived human-induced pluripotent stem cells (hiPSCs) differentiated into hepatocytes (hiPSC-Heps). (A) Scheme showing the urea cycle detoxifying ammonia (NH4+) into nontoxic urea in five consecutive urea cycle enzyme (UCE)–mediated reactions in mitochondria in hepatocytes. (B) Urea secretion in four control hiPSC-Hep lines (Ctrl_1-4)…

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Genetic strategies reverse pesticide resistance

Nature Communications i>In a new empirical study published in, a gene drive designed to bias heredity, called an allelic drive, was applied without pesticide treatment to create natural-level insects that were balanced with pesticide susceptibility. Population that has been shown to be recoverable. Credits: Bier Lab, University of California, San…

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PyTorch’s Cult Following

PyTorch’s popularity spread only three years after its launch: the open-source ML library posted a 194% user growth in the first half of 2019. Since then PyTorch has not looked back. According to the survey by Stackoverflow, while TensorFlow is the most in-demand library, PyTorch is more preferred. Data from…

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Genome research: Finding the invisible

Fig. 1: Ladder-seq uses mRNA length information to aid transcriptome reconstruction. Credit: DOI: 10.1038/s41587-021-01136-7 LMU researchers have developed a method to extract more information from sequencing data. This will afford deeper insights into biology. Higher organisms store their genetic material in the nuclei of cells as deoxyribonucleic acid (DNA). In…

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The membrane structure of inner ear protein prestin is revealed

Force spectroscopy of prestin, the motor protein in the inner ear. Credit: Kanazawa University As mammals, we have very sensitive hearing, thanks to a process known as cochlear amplification. This amplification is down to sensory cells in the inner ear called outer hair cells (OHCs), and it is thought to…

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Researchers identify new bacteria and viruses on human skin

Data representing the diverse range of microbes found in the human skin microbiome. Credit: Karen Arnott/EMBL Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI), the National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI), the NIH National Institute of Arthritis and Musculoskeletal and Skin Diseases, and colleagues have identified…

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Postdoctoral Scientist – Knott Lab – Bioinformatics & Functional Genomics

Requisition # HRC0544032C Principal Investigator, Simon Knott, PhD is looking for a Postdoctoral Scientist to join the team! The Cedars-Sinai Center for Bioinformatics and Functional Genomics (CBFG) is an integrated, interdisciplinary research group with the common goal of developing end-to-end research workflows for genomic and high-throughput functional analysis of patient…

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Researchers identify new bacteria and viruses in human skin

Data representing a variety of microorganisms found in the human skin microflora. Credits: Karen Arnott / EMBL Researchers and colleagues at EMBL’s European Bioinformatics Institute (EMBL-EBI), National Institutes of Health (NIH) National Institute for Human Genome (NHGRI), NIH National Institute for Arthritis, Musculoskeletal and Skin Diseases are new bacteria and…

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The direction of your DNA may be as important as which parent it came from

Fig. 1: H19 gene expression was derepressed on the paternally inherited inverted-ICR allele in fetal livers but not in placentas. a Breeding scheme. In order to distinguish parental origin of the alleles by using SNPs between inbred mouse strains, inverted-ICR heterozygous male mice (WT/INV; C57BL/6J [B6] background) were mated with…

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First time genome editing made possible on cells lining blood vessel walls

Credit: Pixabay/CC0 Public Domain The lab of Youyang Zhao, Ph.D., from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls. This is…

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Introduction to Generative Adversarial Networks with PyTorch

Introduction to Generative Adversarial Networks with PyTorch. A comprehensive course on GANs including state of the art methods, recent techniques, and step-by-step hands-on projects What you’ll learn How Generative Adversarial Networks work internally How to implement state of the art GANs techniques and methods using PyTorch How to improve the…

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The Hot Topic In Probabilistic Programming

One of the biggest challenges of this decade is solving uncertainty, ethical and explainable problems in the thousands of machine learning models we interact with daily. Meta, formerly Facebook, announced the release of their supplement to aid this developing sphere. Bean Machine, Meta’s probabilistic programming system, is a PyTorch-based model…

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Brem Looks at Multiple Treatments for Patients With DLBCL

During a Targeted OncologyTM Case-Based Roundtable event, Elizabeth A. Brem, MD, an assistant professor in Division of Hematology/Oncology, Department of Medicine at UC Irvine Health in Los Angeles, CA, moderated a discussion about a 43-year-old woman with diffuse large B-cell lymphoma. Targeted Oncology™: What therapeutic options would you consider at…

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A year of ToBRFV

Although 2021 was the year of viruses for the entire world population, it was even more so for growers, who were confronted with the infamous Tomato Brown Rugose Fruit Virus (ToBRFV). It has been quite a ride – which is, unfortunately, not over just yet. In order to give you…

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Barriers to Loncastuximab Before CAR T-Cell Therapy in DLBCL

DISCUSSION QUESTIONS Do you foresee any barriers to using loncastuximab tesirine (Zynlonta) in diffuse large B-cell lymphoma (DLBCL)?​ If loncastuximab were covered by insurance, would you use it in the second line for patients who decline transplant?​ DEVA NATHAN, MD: I have different question. Are you willing to replace R-CHOP [rituximab…

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Translocations on chromosome 6 cause abnormalities during meiosis, resulting in fewer watermelon seeds

Credit: Unsplash / CC0 public domain Watermelon (Citrullus lanatus) is an economically important horticultural crop and one of the top five most widely consumed fresh fruits in the world. Compared to traditional seedless watermelons, seedless watermelons are preferred by consumers, show better fruit quality and bring greater economic benefits to…

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BioSpace hiring Bioinformatics Scientist in Bethesda, Maryland, United States

We are currently searching for a Bioinformatics Scientist to provide support services to satisfy the overall operational objectives of the Center for Alzheimer’s and Related Dementias, National Institute on Aging. The primary objective is to provide services and deliverables through performance of support services. This opportunity is full-time, and it…

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Human microRNA inhibits expression of pathogenic gene underlying facioscapulohumeral muscular dystrophy

Fig. 1: miR-675 targets the DUX4 ORF and 3′UTR. a RenLuc-DUX4-FL dual-luciferase reporter and CMV.H19 constructs, and U6.MIR675, H1.MIR675, U6.MIR675-3p, and U6.MIR675-5p miRNAs. RenLuc-DUX4-FL contains DUX4 ORF and 3′UTR sequences fused to Renilla luciferase after the stop codon. Exons 1–3 are indicated (Ex1,2,3). *SD5 indicates silent mutation of a cryptic…

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Promising new treatment for patients with diffuse large B-cell lymphoma

Hodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0 A study from Memorial Sloan Kettering Cancer Center (MSK) published today in the New England Journal of Medicine (NEJM), found that in patients with previously untreated Diffuse Large B-Cell Lymphoma (DLBCL) Polatuzumab vedotin with Rituximab, Cyclophosphamide, Doxorubicin,…

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laboratory jobs in germany

We wish you a good luck and have a prosperous career. Working at Labcorp | Jobs and Careers at Labcorp 15 GNeuS Postdoc Positions in Neutron Science of 24 Months Each (Full-time Job) FZJ – Forschungszentrum Jülich. What other similar jobs are there to Laboratory jobs in Germany? Clinical Laboratory…

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Code of Conduct | PyTorch-Ignite

In the interest of fostering an open and welcoming environment, we as contributors and maintainers pledge to make participation in our project and our community a harassment-free experience for everyone, regardless of age, body size, disability, ethnicity, sex characteristics, gender identity and expression, level of experience, education, socio-economic status, nationality,…

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Fairring (FAIR + Herring) is a plug-in for PyTorch that provides a process group for distributed training that outperforms NCCL at large scales

TL;DR: Using a variation on Amazon’s “Herring” technique, which leverages reduction servers, we can perform the all-reduce collective faster than NCCL: up to 2x as fast as NCCL in microbenchmarks up to 50% speedup in end-to-end training workloads You can use it right away in your project, with no code…

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BioSpace hiring Bioinformatics Python Developer in Rockville, Maryland, United States

We are currently searching for a Bioinformatics Python Developer to provide support to the National Institutes of Health (NIH). This opportunity is a permanent, full-time position with MSC, and it is on-site in Rockville, MD. Duties & Responsibilities The role will be responsible for developing and extending software solutions for…

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New biosensor sheds light on CRISPR gene editing

ORNL’s biosensor system reveals the CRISPR activity of poplar plants that glow bright green under UV light compared to normal plants that appear red.Credits: Guoliang Yuan / ORNL, US Department of Energy Using technology developed at the Oak Ridge National Laboratory of the Department of Energy, it is now possible…

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New biosensors shine a light on CRISPR gene editing

ORNL’s biosensor system reveals CRISPR activity in poplar plants, which glow bright green under ultraviolet light, compared to normal plants, which appear red. Credit: Guoliang Yuan/ORNL, U.S. Dept. of Energy Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now…

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Nanotechnology for genome editing in multiple muscles simultaneously

Fig. 1: LNP-mediated Luc-mRNA or CRISPR-Cas9 mRNA/sgRNA delivery into muscle tissue. a Schematic illustration of LNP-CRISPR. Either Luc mRNA or Cas9 mRNA/sgRNA is encapsulated into LNP that consists of TCL053, DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycol-dimyristoyl glycerol), and cholesterol. b Chemical structure of the newly synthesized ionizable lipid, TCL053. c Representative…

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A gallery of human RNA polymerases

The Müller group’s research provides the most detailed structural information yet about human RNA polymerase I. Cryo-electron microscopy has significantly improved as a powerful tool, offering scientists greater insight into what this enzyme looks like and how it works in human cells. Credit: Müller group/EMBL Using state-of-the-art technology and techniques,…

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Using DNA to study fungal communities

This Pinus banksiana forest with a rich Arctostaphylos uva-ursi and Vaccinium sp. understory was a collection site in this study examining how disturbance affects fungal community diversity, while simultaneously testing how sequencing methods compare in characterizing communities of plant root symbionts. Credit: Natalie Scott Fungi tend to be absent in…

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An exercise-regulated noncoding RNA counteracts muscle aging

Credit: CC0 public domain In a collaborative effort between EPFL, NTNU Norway, and CBMR Danish laboratories, researchers investigated the molecular effects of exercise on non-coding RNA genes in skeletal muscle. Scientific translation medicine.. In this study, they discovered the long non-coding RNA “CYTOR” and investigated its role in rodent, worm,…

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Does use of electronic devices affect mental traits?

Credit: CC0 Public Domain In a study published in Addiction Biology, investigators found significant associations between use of electronic devices and signs of depression and anxiety, as well as cigarette smoking and alcohol drinking. The team also found certain genetic variants that were linked with these traits. The study included…

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Improving DNA storage with nanoscale electrode wells

DNA data storage requires higher synthesis throughput than is possible with current techniques. (A to D) Overview of the DNA data storage pipeline. (A) Digital data are encoded from their binary representation into sequences of DNA bases, with an identifier that correlates them with a data object, addressing information that…

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Post-Doctoral position : Virus Genomic Epidemiology / Bioinformatics – Institut Pasteur de Paris – Virologie – job portal

Emploi Équipe: Génomique évolutive des virus à ARN Équipe: Hub de Bioinformatique et Biostatistique Centre de Référence: Virus Influenzae Département de: Virologie Membre : Etienne Simon-Loriere Membre : Christophe Malabat Domaines Scientifiques Maladies Organismes Technique Date limite pour l’application 31 Dec 2021 The National Reference Center for viruses of respiratory…

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RNA-targeting enzyme expands the CRISPR toolkit

McGovern Fellows Jonathan Gootenberg (left) and Omar Abudayyeh in their lab. Credit: Caitlin Cunningham Researchers at MIT’s McGovern Institute for Brain Research have discovered a bacterial enzyme that they say could expand scientists’ CRISPR toolkit, making it easy to cut and edit RNA with the kind of precision that, until…

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What does it mean BLASTx in de novo RNAseq analysis?

What does it mean BLASTx in de novo RNAseq analysis? 1 Hi, all. I try to get an assembly stat. According to some articles, it tends to have information that can be obtained by BLAST. For example, “Top BLASTx-hit species” and “Percent of gene with at least one BLASTx hit…

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CVC Files Opposition to ToolGen Substantive Motion No. 1 | McDonnell Boehnen Hulbert & Berghoff LLP

On July 15th, Junior Party the University of California/Berkeley, the University of Vienna, and Emmanuelle Charpentier (collectively, “CVC”) filed its Opposition to Senior Party ToolGen’s Substantive Motion No. 1 for benefit of priority to U.S. Provisional Application No. 61/837,481, filed June 20, 2013 (“P3” or “ToolGen P3”), or alternatively, International…

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Cristae-dependent quality control of the mitochondrial genome

S. cerevisiae cells distinguish between WT and mutant mtDNA. (A) Schematic illustration of the pedigree analysis. Two Δarg8 yeast strains harboring WT or Δcob::ARG8 mtDNA were mated. Zygotes were isolated, and daughter cells from up to five consecutive generations were separated and placed on free spots on the agar plate…

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Lake Superior Has Seen Half A Dozen Blue-Green Algae Blooms This Year

A decade ago, a blue-green algae bloom had never been reported on Lake Superior. Now, half a dozen blue-green algae blooms have been reported this summer across Lake Superior, including one that formed recently in Superior. But researchers say the blooms were relatively minor.  The Wisconsin Department of Natural Resources is…

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The faces of three ancient Egyptians appeared thanks to the remains of DNA more than 2,000 years ago

The faces of three ancient Egyptians are brought back to life thanks to DNA group of scientists Recreate The faces of three ancient Egyptian men using DNA that is more than 2,000 years old. According to the magazine NEWSWEEKIt is believed that this is the first time that modern techniques…

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MD Anderson Cancer Center hiring Research Assistant I – Bioinformatics in Houston, Texas, United States

SummaryThe primary purpose of the Research Assistant I position is to provide expertise in bioinformatics and biostatistics regarding the crucial link between raw data and its use by the biologist/physician requesting the research study, while adhering to standard operating procedures. CORE VALUES Caring Behaviors Courtesy: Is respectful and courteous to…

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Our immune system is as unique as a fingerprint or our DNA

Double-stranded DNA fragment. Credits: Vcpmartin / Wikimedia / CC BY-SA 4.0 Everyone seems to have a completely unique immune system. Researchers at Utrecht University discovered this immune diversity after mapping antibodies from healthy and sick people. This finding may help explain, for example, why the corona vaccine appears to be…

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How climate change could impact algae in the global ocean

Scientists sample a brown mat of aggregated phytoplankton. Credit: Katrin Schmidt Global warming is likely to cause abrupt changes to important algal communities because of shifting biodiversity ‘break point’ boundaries in the oceans—according to research from the University of East Anglia and the Earlham Institute. A new study, published today…

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Dnaman software manual

Dnaman software manual DNADynamo DNA Sequence Analysis SoftwareCLC Genomics Workbench – Qiagen They have sent a man to locate the key. He was making notes with a slim gold pen on a Gucci pad? When I married my husband, that all…

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Invitae hiring Bioinformatics Scientist/Engineer in San Francisco, California, United States

Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry, by making genetic testing affordable and accessible for everyone to…

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FTC to take on Trump’s vertical merger guidelines

With help from John Hendel and Leah Nylen — Agency agenda: The FTC plans to rescind Trump-era vertical merger guidelines at today’s open meeting. But how much will that really change? — Broadband moves: As House committees wrap up their portions of Democrats’ social spending package , some lawmakers are…

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Sports Field Breeding Gets a Boost

University of Oklahoma Gaylord Family Oklahoma Memorial Stadium, located in Norman, Oklahoma. Source: Pure Seed Mowing down the competition takes effort, but breeding turfgrass for athletic fields brings a new, creative challenge to the industry. Attitudes about the appropriate playing surface for athletic fields have evolved in recent years, resulting…

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Could protein engineers have built the next billion pound pharma company?

Peptone is using science to build the world’s first protein engineering operating system, combining AI with computational molecular physics. Above, a 3D illustration of proteins. Photo: Getty Life comes at you fast. At one point Peptone, a computational biophysics company, had been rejected by more than 150 investors. Now, it…

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New research provides an additional overview of optimistic reasons related to heart regeneration

CRISPR / Cas9 Wls knockdown in cardiomyocytes promotes cardiac fibroblast proliferation during neonatal cardiac regeneration. Green indicates vimentin-positive cardiac fibroblasts. Red indicates cells that are proliferating with the EdU label. Blue indicates nuclei with DAPI staining. Credit: Texas Heart Institute Texas Heart Institute has new research from its abundant cardiomyocyte…

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Invitae hiring Bioinformatics Engineer Lead in Irvine, California, United States

Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry, by making clinical-grade genetic information affordable and accessible to guide…

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Senior Bioinformatics Data Scientist – Invitae

Location: San Francisco, CA or Remote in USA Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people! Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry by making…

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Bioinformatics Analyst at Invitae

  Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine in order to improve healthcare for billions of people. The Clinical Informatics team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry by making clinical-grade genetic information…

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Future ‘Exceedingly Bright’ for Kidney Stone Prevention

Gene therapy, new therapeutics currently in clinical trials, and a promising dietary supplement are feeding the optimism of kidney stone expert Glenn Preminger, MD. Glenn Preminger “The future of kidney stones looks exceedingly bright,” said Preminger, professor of urology at Duke University in Durham, North Carolina, during his lecture at…

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Genetic resource could be used to protect farm-raised kuruma shrimp from disease

Kuruma shrimp are considered a delicacy in Japan. Credit: OIST New research from the Okinawa Institute of Science and Technology Graduate University (OIST) and Tokyo University of Marine Science and Technology has resulted in a useful genetic resource on the kuruma shrimp. These are one of the largest species of…

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Scientists use gene editing tool to target mosquito-spread disease

CRISPR/Cas9 based kmo knock-in cassette. Representation of the kmo locus and HDR donor construct for integration. Grey arrows represent exons and the red vertical line indicates the sgRNA target site within exon 5. The dark gray lines indicate the left and right homology arm sequences (LHA and RHA, respectively). In…

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Lecturer in Bioinformatics at Queen’s University Belfast

The School of Medicine, Dentistry and Biomedical Sciences is currently seeking to appoint an exceptional candidate to the post of Lecturer in Bioinformatics to undertake research in the Patrick G Johnston Centre for Cancer Research and the School of Medicine, Dentistry and Biomedical Sciences at Queen’s University Belfast (QUB). The…

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New programmable gene editing proteins found outside of CRISPR systems

Left: Han Altae-Tran (Credit: Zhang Lab). Right: Soumya Kannan. Credit: Caitlin Cunningham Within the last decade, scientists have adapted CRISPR systems from microbes into gene editing technology, a precise and programmable system for modifying DNA. Now, scientists at MIT’s McGovern Institute and the Broad Institute of MIT and Harvard have…

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Senior Machine Learning/Bioinformatics Software Engineer, Research – Invitae

Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry, by making genetic testing affordable and accessible for everyone to…

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Treatment with gene therapy of a new rat model of Morquio A

Histological analysis of sections of the growth plate (GP), the active bone growth area. Left panel, the GP of a healthy rat. Middle panel, GP from a Morquio A rat, showing severely reduced growth activity. Right panel, the GP from a Morquio A rat treated with the gene therapy, in…

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Treatment of a new rat model of Morchio A with gene therapy

Histological analysis of sections of the growth plate (GP), which is an active bone growth area. Left panel, GP of healthy rats. The central panel, GP of Morchio A rats, shows a significant decrease in growth activity. Right panel, GP of Morchio A rats treated with gene therapy. Growth activity…

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A new gold standard for detecting cancer mutations

Credit: DOI: 10.1038 / s41587-021-00994-5 International collaborative research has identified a new gold standard for detecting cancer mutations using genomic pathology. Professor Sulev Kõks of the Center for Molecular Medicine and Innovative Therapies at Murdoch University and the Peron Institute said: “We found that factors such as sample and library…

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How much does the DNA extraction route impact the results of microbiome research?

Comparing DNA extractions for microbiome studies. Credit: Tess Deyett Let’s face it, we are a results-driven society. Too focused on the outcome, people don’t often think about the “how.” For instance, did you think about “how” you got to work this morning or did you just get there? In microbiome…

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A new gene-delivery vehicle could make gene therapy for muscle diseases safer and more effective

Credit: CC0 Public Domain Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure. Some gene therapies that use a harmless virus to deliver a functioning copy of a disease-causing gene to cells have shown promise in clinical trials for a…

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Personal chemistry

Philipp Geyer was interested in learning how protein levels in the blood change when a person tries to lose weight. Several years ago, Geyer, then a postdoctoral fellow, and his colleagues in Matthias Mann’s lab at the Max Planck Institute of Biochemistry began to analyze samples from a dieting study,…

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Novel tool counts T cells quickly helping predict patient response to cancer therapy

Credit: CC0 Public Domain Scientists at UCL and the Francis Crick Institute, London, have developed a new tool, which can rapidly estimate the number of T cells (immune cells) in a cancerous tumor; with T cell abundance helping predict a patient’s response to immunotherapy, researchers are hopeful this could enable…

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Invitae hiring Field Bioinformatics Scientist in United States

Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry by making genetic testing affordable and accessible for everyone to…

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Evidence for how a key transcription factor manages access to DNA

Credit: CC0 Public Domain CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC. Scientists at St. Jude Children’s Research Hospital have found direct evidence that CTCF governs chromatin accessibility, the process of opening tightly spooled DNA so…

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DNA tool transforms nature tracking

Some animals, like the Amazon pink river dolphin are tricky to track using conventional methods. In their search for pink river dolphins, researchers in the Peruvian Amazon scooped up river water sloshing with genetic material that they hoped could trace the elusive creatures. They found what they were looking for….

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Deadly koala virus being passed to joeys from mum

Credit: University of Queensland A deadly koala virus that can cause immune depletion and cancer, known as koala retrovirus, is being transferred to joeys from their mothers, according to University of Queensland scientists. Associate Professor Keith Chappell, from UQ’s School of Chemistry and Molecular Biosciences, said the virus predisposes koala…

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Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity

Innate immunity is the first line of defense against microbial infection. In response to RNA virus infection, mitochondrial antiviral signaling protein (MAVS) plays an important role in innate antiviral immune responses. Arginine methylation is a Post-translational Modification (PTM) in histone and non-histone proteins that can affect numerous cellular activities. Previous…

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Where is the annotation file if using the GtRNAdb (tRNA SE analysis) for mapping to RNAseq libraries?

Where is the annotation file if using the GtRNAdb (tRNA SE analysis) for mapping to RNAseq libraries? 0 Hi all, On the GtRNAdb (tRNA-SE analysis) website there is a file containing fasta sequences of different tRNA genes. gtrnadb.ucsc.edu/genomes/eukaryota/Hsapi38/ I aligned this GtRNAdb database with RNAseq libraries using bowtie2 and got…

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Research Bioinformatician II – Knott Lab

Research Bioinformatician II – Knott Lab – Bioinformatics & Functional Genomics Apply Now Share Requisition # HRC0654414 The Knott Laboratory at Cedars-Sinai Medical Center is seeking to hire a highly motivated computational scientist to fill the position of Research Bioinformatician II! This position provides excellent…

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CyberCoders hiring Bioinformatics/Data Scientist – Well-Funded/Gene Editing Startup in Cambridge, Massachusetts, United States

If you are a Bioinformatics/Data Scientist with relevant algorithm development, high-throughput/nextgen sequencing and biomarker identification experience, please read on! Based in Cambridge, we are a rapidly growing biotech company focused on leveraging cutting-edge genome editing tech to accelerate drug discovery and develop novel therapeutics for a broad range of genetic…

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Biologist Bioinformatics Server Administration Job in CLAY CENTER, NE

Overview Open & closing dates Opening and closing dates 09/02/2021 to 09/16/2021 Service Competitive Pay scale & grade GS 9 – 11 Salary $53,433 to $84,049 per year Appointment type Permanent Work schedule Full-time Locations 1 vacancy in the following location: Relocation expenses reimbursed No Telework eligible Yes as determined…

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Image Data Specialist – Euro-BioImaging at European Molecular Biology Laboratory (EMBL)

About the team/job The Euro-BioImaging Bio-Hub hosted by the European Molecular Biology Laboratory (EMBL) is looking for a highly motivated image data specialist to technically support the Image Data Services of the European research infrastructure Euro-BioImaging ERIC (www.eurobioimaging.eu). Euro-BioImaging is building and offering image data services to the research community….

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Bioinformatics AMD Manager | Government Jobs

Effective date: June 29, 2021 Contents 1.Introduction 2.About this Policy 3.Information We Collect About You 4.Our Use of Your Information 5.Information We Disclose 6.Your Data Rights 7.Retention and Removal 8.Cookies and similar Tracking Technologies; “Do Not Track” 9.Information Security and Integrity 10.Information on Children 11.Your California Privacy Rights 12.Your Nevada…

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Dried Blood Spots From Newborn Screening Can Help Identify The Cause Of Sudden Cardiac Death In The Young

Credit: CC0 Public Domain The underlying cause of sudden cardiac death (SCD) in a young person is often difficult to identify. A genetic analysis could provide more information in many cases, but blood samples are not collected routinely at the time of death, and DNA extracted from the tissues collected…

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Rare barley mutation with potential

Seven-day-old barley roots of mutant egt2: It grows strictly downwards (hypergravitropic). Credit: Gwendolyn Kirschner The importance of the root system for agricultural yields is often underestimated. Whether roots can access water and nutrients effectively also determines the resilience of important crops to drought and climate change. Researchers from the Universities…

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New CRISPR-Cas system cuts virus RNA

Credit: DOI: 10.1126/science.abk2718 Researchers from the group of Stan Brouns (Delft University of Technology) have discovered a new CRISPR-Cas system that cuts RNA. The study will be published on August 26 in Science and is expected to offer many opportunities for the development of new applications in genetic research and…

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The association of amino acids with various common illnesses can help predict an individual’s risk

Mitochondria.Credits: Wikipedia Commons One of the first population-scale studies on how common genetic traits are affected by changes in mitochondrial DNA, the driving force of human cells, was the European Molecular Biology Laboratory at the Wellcome Trust Sanger Institute, University of Cambridge, EMBL. Tokoro (EMBL-EBI) and its collaborators. The team…

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Link between amino acid and a range of common diseases could help predict personal risk

Mitochondria.Credits: Wikipedia Commons One of the first population-scale studies on how common genetic traits are affected by changes in mitochondrial DNA, the driving force of human cells, was the European Molecular Biology Laboratory at the Wellcome Trust Sanger Institute, University of Cambridge, EMBL. Tokoro (EMBL-EBI) and its collaborators. The team…

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Initu extraction and detection of DNA using nanopores

Extraction and detection of single-molecule DNA from cells using 3D integrated nanopores. Credit: Makusu Tsutsui et al. The ability to detect DNA from a single cell is important for the detection of diseases and hereditary diseases. Measurement of a single DNA molecule has long been possible. However, the sample cannot…

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New CRISPR-based technology that speeds up the identification of genes involved in health and disease

Which gene is MIC-Drop is a new CRISPR-based technology for quickly and efficiently screening the function of hundreds of zebrafish genes to better understand human health and disease. A glass needle filled with MIC-Drops (colored droplets) is used to inject fertilized zebrafish eggs (translucent spheres). MIC-Drops are dyed in a…

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Biologist Bioinformatics Job in GLENSIDE, PA

Overview Open & closing dates Opening and closing dates 08/16/2021 to 09/16/2021 Service Competitive Pay scale & grade GS 12 – 13 Salary $84,231 to $130,211 per year Appointment type Permanent Work schedule Full-time Locations 1 vacancy in the following location: Relocation expenses reimbursed No Telework eligible Yes as determined…

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Open Science and Research Information Officer (Heidelberg, DE or Hinxton, UK)

Description Open Science and Research Information Officer (Heidelberg, DE or Hinxton, UK) – 2 positions available Location: Heidelberg, Germany Staff Category: Staff Member Contract Duration: 3 years (renewable) Grading: 4, 5 or 6; depending on qualifications and experience Closing Date: 19 September 2021 Reference Number: HD02025 EMBL is looking for…

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China approves first combination vaccine trial as delta spreads

This study tests the efficacy of a combination of a Chinese Sinovac “inactivated” vaccine and a DNA-based vaccine. China’s drug regulators have approved the country’s first combination vaccine trial because the rapid spread of Delta variants has raised concerns about the effectiveness of domestic jabs, the company involved in the…

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Positive preliminary data on CRISPR treatment for blood diseases

Credit: CC0 public domain Stephan Grupp, MD, Ph.D., Chief and Medical Director of the Cell Therapy and Transplantation Section of the Institute for Cell and Gene Therapy at the Philadelphia Children’s Hospital (CHOP) and the first pioneer in cell immunotherapy in childhood. A collaborative team of researchers, including Cancer, recently…

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