Tag: GSCs

G9a promotes immune suppression by targeting the Fbxw7/Notch pathway in glioma stem cells

Aim: Immunotherapy for glioblastoma multiforme (GBM) is limited because of a strongly immunosuppressive tumor microenvironment (TME). Remodeling the immune TME is an effective strategy to eliminate GBM immunotherapy resistance. Glioma stem cells (GSCs) are inherently resistant to chemotherapy and radiotherapy and involved in immune evasion mechanism. This study aimed to…

Continue Reading G9a promotes immune suppression by targeting the Fbxw7/Notch pathway in glioma stem cells