Tag: H1299
HOXC-AS3 as an Oncological Biomarker and Therapeutic Target
1Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, 330008, People’s Republic of China; 2Department of General Surgery, Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang, Jiangxi, 332007, People’s Republic of China; 3Queen Mary School, Nanchang University, Nanchang, Jiangxi, 330038, People’s Republic of China Correspondence: Hongliang Luo,…
TRIM25 targets p300 for degradation
Introduction Protein levels are regulated at several nodes. One mode of protein level regulation acts through enhancing or reducing gene transcription. Gene transcription can be stimulated by binding transcription factors to promoters or enhancers of target genes and by posttranslational modifications of transcription factors and histones. Such modifications can be…
ncRNA | Free Full-Text | The Intergenic Type lncRNA (LINC RNA) Faces in Cancer with In Silico Scope and a Directed Lens to LINC00511: A Step toward ncRNA Precision
CRC Upregulated 153-5p HIF-1 activates LINC00511, targeting HIF-1’s 3-UTR and +ve feedback loop [78] Oncogene Human CRC tissues vs. paired adjacent non-tumor and CRC cell lines HT29, LOVO, SW620, SW480 vs. normal colon epithelial FHC cell line and athymic BALB/c nude mice for implantation – HNF4 promotes LINC00511 transcription, interaction…
The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer
Cell lines and culture conditions All media and supplements were purchased from Gibco unless otherwise stated. OC cell line SKOV3, OVCA429, CH1 and NSCLC cell line H1299 and A549 were maintained using Dulbecco’s Modified Eagle Medium (DMEM) media supplemented with 10% (v/v) foetal bovine serum (FBS). OC cell lines HeyA8,…
GlaI cleavage assistant isothermal exponential amplification coupling with CRISPR/Cas12a for ultrasensitive detection of CLDN11 methylation: a potential marker for lung adenocarcinoma,Sensors and Actuators B: Chemical
DNA methylation is closely associated with cancer, and sensitive detection of DNA methylation is immensely significant for early cancer screening. In this study, for the first time, we identified CLDN11 methylation as a valuable marker for lung adenocarcinoma diagnosis and prognosis based on database analysis and experimental verification using clinical…
Role of the epithelial-mesenchymal transition-related circular RNA, circ-10720, in non-small-cell lung cancer
Please use this identifier to cite or link to this item: hdl.handle.net/2445/184005 Title: Role of the epithelial-mesenchymal transition-related circular RNA, circ-10720, in non-small-cell lung cancer Author: Martín, JaraCastellano, Joan JosepMarrades Sicart, Ramon Ma.Canals, JordiViñolas Segarra, NúriaDíaz Sánchez, TaniaMolins López-Rodó, LaureanoMartinez, DanielHan, BingMoisés, JorgeHe, YangyiMonzó Planella, MarianoNavarro Ponz, Alfons Keywords: Càncer…
RAGA prevents tumor immune evasion of LUAD by promoting CD47 lysosome degradation
RAGA regulates lung adenocarcinoma progression and macrophage phagocytosis We performed experiments to explore the role of RAGA in lung adenocarcinoma by in vitro cell culture and in vivo xenograft system. To this end, we generated RAGA knockdown A549 and H1299 cancer cells. In vitro cell proliferation assays showed that RAGA…
E3 ubiquitin ligase FBXW7 enhances radiosensitivity of non-small cell lung cancer cells by inhibiting SOX9 regulation of CDKN1A through ubiquitination
. 2022 Nov;102(11):1203-1213. doi: 10.1038/s41374-022-00812-9. Epub 2023 Jan 4. Affiliations Expand Affiliations 1 The Affiliated Tumor Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, 830000, Urumqi, China. 2 The Affiliated Tumor Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, 830000, Urumqi, China. Electronic address: lclchunling56@163.com. Item in Clipboard…
