Tag: HPV
Do preteens really need an HPV vaccine?
by Dr. Rebekah Fenton and Dr. Rebecca Perkins Gardasil vaccine and box. Image: Wikipedia Q: Why is it important for my 10-year-old to get the HPV vaccine? A: If you are the parent of a preteen who is between the ages of 9 and 12, it’s time to make sure…
Using CRISPR/Cas to develop biosafety materials
The diagnosis and treatment of viral infections, especially those that cause large-scale outbreaks, is urgently needed, as the lack of these measures allows epidemics to progress. A new Biosafety and Health study discusses the use of the highly efficient clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated proteins (Cas) technology to…
Optimization of cerebrospinal fluid microbial DNA metagenomic sequencing diagnostics
We implemented a metagenomic DNA sequencing methodology to unbiasedly detect microbial species in CSF samples from patients with CNS symptoms in which a pathogen or EBV had been detected (Additional 3: Table 1). Samples positively identified with pathogen-specific quantitative PCR (qPCR), 16S rRNA gene sequencing or bacterial/mycotic culture in CSF…
Phospholipase A2 inhibitor and LY6/PLAUR domain-containing protein PINLYP regulates type I interferon innate immunity
Significance Interferon (IFN)-mediated antiviral responses serve as the first line of the host innate immune defense against viral infection. Here we identify a previously uncharacterized protein designated phospholipase A2 inhibitor and LY6/PLAUR domain-containing protein (PINLYP), which is essential for embryonic development and plays an important role in type I IFN…
CRISPR/Cas12a Powered DNA Framework-Supported Electrochemical Biosensing Platform for Ultrasensitive Nucleic Acid Analysis
Nucleic acid analysis using ultrasensitive and simple methods is critically important for the early-stage diagnosis and treatment of diseases. The CRISPR/Cas proteins, guided by a single-stranded RNA have shown incredible capability for sequence-specific targeting and detection. Herein, in order to improve and expand the application of CRISPR/Cas technology to the…
BioChain announces expanded line of NGS characterized bio-samples for oncology researchers
NEWARK, Calif., Sept. 22, 2021 /PRNewswire/ — BioChain Institute, (“BioChain”), a leader in high quality processed bio-sample products, announced an expanded line of Next Generation Sequencing (NGS) characterized bio-samples encompassing a variety of cancer-related mutations available for preclinical drug development and as reference samples for CLIA labs. “Scientists are looking for…
Genotype distribution and prevalence of human papillomavirus
Introduction Cervical cancer (CC) is the second most deadly disease among women in the world and is the leading cause of death from cancer.1 In 2018, there were 570,000 new diseases and 311,000 deaths worldwide.2 Viral infections contribute to 15–20% of all cancers, and several viruses play an important role…
National Health Commission responds on concerns about a third dose for people with high risk
Is it necessary to take the COVID-19 booster dose and are there any suggestions on traveling during the upcoming Mid-Autumn Festival and National Day holidays? These are some of the questions that are being raised currently. Here are the answers from the National Health Commission, which held a press conference…
Answers to commonly asked questions, KNEWS
As of July 2021, the coronavirus vaccine has been added to the National Vaccination Program for children and adolescents aged 12-17. Here are the most commonly asked questions and answers about the COVID-19 vaccine provided by the National Vaccination Committee. I hesitate to vaccinate my child because these vaccines…
