Tag: HR
Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer
Cell-type annotation scRNA-seq data were filtered to discard low-quality cells and doublets (Supplementary Fig. 1, Extended Data Fig. 1 and Methods). Supervised clustering (Reference Component Analysis v2 (RCA2)) at low resolution grouped cells into 11 major cell types (Extended Data Fig. 1). To identify epithelial cell subtypes, we initially analyzed…
AstraZeneca and Merck – Results From Phase 3 PROpel Trial of LYNPARZA (olaparib) Plus Abiraterone in First-Line Metastatic Castration-Resistant Prostate Cancer Published in NEJM Evidence
RAHWAY, N.J. – AstraZeneca and Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced that the results from the Phase 3 PROpel trial have been published in NEJM Evidence. Results from the trial showed that LYNPARZA in combination with abiraterone plus prednisone significantly improved radiographic progression-free…
Alpelisib Plus Olaparib Phase 1b Clinical Trial for Patients With Advanced Triple-Negative Breast Cancer
For a study, researchers sought to present the breast cancer cohort. In a previous study, they reported on safety. They recommended a phase 2 dose (RP2D) of olaparib combined with the PI3Kα-specific inhibitor alpelisib in patients with high-grade serous ovarian cancer as studied in a phase 1b trial (NCT01623349). Investigators…
Medical Coding job For Biotech,Biomedical graduates in Alpha Medical Coding Solutions at
Position: Medical Coder Ct : Uma HR – 9042912356 7806897286(whatsapp) Job Description: Medical Coding is the process of converting patient health information into alpha numeric codes. Coders take medical reports from doctors, which may include a patients condition, the doctors diagnosis, a prescription, and whatever procedures the doctor or healthcare…
Bioinformatics Programmer I – 115257
UCSD Layoff from Career Appointment: Apply by 04/04/2022 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor. Special Selection Applicants: Apply by 04/14/2022. Eligible Special Selection clients should contact their Disability Counselor for assistance. The Department of Medicine (DOM) is the largest department within the…
Nirogacestat Yields Positive Findings in Progressing Desmoid Tumors
Findings from the phase 3 DeFi study indicated that treatment with nirogacestat met the trial’s end points in patients with progressing desmoid tumors. Investigators reported positive topline findings from the double-blind placebo controlled phase 3 DeFi trial (NCT03785964), assessing the use of nirogacestat as a treatment for adult patients with…
Role of mitochondrial DNA copy number in incident cardiovascular diseases and the association between cardiovascular disease and type 2 diabetes : A follow-up study on middle-aged women
@article{3a468481-6140-491c-b3ea-22a00f1d6e03, abstract = {{<p>BACKGROUND AND AIMS: Mitochondrial DNA copy number (mtDNA-CN) is a surrogate biomarker of mitochondrial dysfunction and is associated with type 2 diabetes (T2D) and cardiovascular disease (CVD). However, despite being associated with both CVD and T2D, it is not known what role mtDNA-CN has in the association…
Role of CD68 in tumor immunity and prognosis prediction in pan-cancer
Expression of CD68 in pan-cancer First, to fully clarify the expression of CD68 in pan-cancer, we matched the GTEx normal samples with TCGA tumor samples (Fig. 1A). We found that the levels of CD68 were significantly elevated (P < 0.01) in colon adenocarcinoma (COAD), glioblastoma multiforme (GBM), kidney renal clear cell carcinoma (KIRC),…
Mulugeta Metaferia – Academia.edu
Mulugeta Metaferia – Academia.edu Academia.edu no longer supports Internet Explorer. To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser. Academia.edu uses cookies to personalize content, tailor ads and improve the user experience. By using our site, you agree to our…
Jobs from VUB, Medicines for Europe, ECOS, INREV, EMBL, DCI, IBMA, Han…
Fundraising Officer/Coordinator DCI – Defence for Children International Brussels Work with all national sections, individually and at regional level, as well as the International Secretariat, to identify rights of the child funding needs in line with DCI… Posted 1 day ago Collaboratorium Project Manager EMBL – European Molecular Biology Laboratory…
Director, Institute of Bioinformatics-UGA FACULTY INTERNAL SEARCH – Athens
*Posting Number:*F0672P*Working Title:*Director, Institute of Bioinformatics-UGA FACULTY INTERNAL SEARCH*Department:*VPR-Inst of Bioinformatics*About the University of Georgia:*The University of Georgia (UGA), a land-grant and sea-grant university with statewide commitments and responsibilities, is the state’s oldest, most comprehensive, and most diversified institution of higher education ([www.uga.edu/%5D(www.uga.edu/)). UGA is currently ranked among the top…
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Bioinformatics Specialist (Pathology and Laboratory Medicine) at University of Pennsylvania in Philadelphia, Pennsylvania
Job Description: Bioinformatics Specialist (Pathology and Laboratory Medicine) University Overview The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey….
N6-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance | Military Medical Research
Bioinformatics analyses revealed the involvement of m6A modification in cervical cancer progression To better understand whether and how m6A regulators contribute to cervical cancer progression, we first identified 9 m6A writers (WTAP, ZC3H13, METTL3, METTL14, METTL16, VIRMA, RBM15B, RBM15, and CBLL1), 15 m6A readers (FMR1, hnRNPA2B1, hnRNPC, YTHDF1/2/3, YTHDC1/2, LRPPRC,…
Genomic Stratification of Resectable CRLM Patients & Implications for Adjuvant Therapy and Survival
For a study, the researchers sought to see if genomic risk groups discovered by colorectal liver metastasis (CRLM) somatic mutation testing may be used for “molecularly-guided” adjuvant systemic chemotherapy and hepatic artery infusion of FUDR (SYS+HAI-FUDR). A prospective institutional database was analyzed for consecutive patients with resected CRLM and available…
A hypoxia-related signature in lung squamous cell carcinoma
Introduction Lung cancer is the major leading cause of tumour-related deaths throughout the world, while lung squamous cell carcinoma (LUSC) as the second most common histological type of lung cancer.1 Each year, almost 1.8 million people are diagnosed with lung cancer worldwide and 400,000 of these die from LUSC.2,3 Due to…
Does Norepinephrine Metabolite DOPEGAL Turn Tau Toxic?
08 Apr 2022 What makes tau toxic? In the March 24 Nature Structural & Molecular Biology, researchers led by Keqiang Ye at Shenzhen Institute of Advanced Technology, China, suggest a new culprit, a norepinephrine metabolite known as DOPEGAL, which is produced only in the locus coeruleus (LC). The authors found…
Innovative site-specific anti-HER2 antibody-drug conjugate
Introduction Antibody-drug conjugates (ADCs) have been studied for decades as a promising cancer treatment. As compared to conventional chemotherapy, ADCs have a larger therapeutic window because of their ability to target antigen-expressing tumor cells.1 As ADC drug development technology continues to evolve, several ADC drugs are being introduced to the…
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Cholangiocarcinoma, or bile duct most cancers, is lethal even when caught early. The 5-year survival rate amongst these identified early is 17% to 25%; for many sufferers, the speed is under 10%. Experts say the important thing to bettering these dismal statistics is to give attention to the various genetic…
Bioinformatics Application Scientist – Carlsbad
Job Description Bioinformatics Application Scientist (Actual title will depend on qualification and experience, including director level appointment) The Company: Universal Sequencing Technology Corporation (universalsequencing.com), a leading NGS biotechnology company engaged in long range/long read sequencing technology is relocating its headquarters from the greater Boston area to Carlsbad, CA where R&D…
Polatuzumab Vedotin Plus R-CHP Recommended for EU Approval for Previously Untreated DLBCL
The European Medicines Agency’s Committee for Medicinal Products for Human Use has adopted a positive opinion in favor of the approval of polatuzumab vedotin for use in combination with rituximab plus cyclophosphamide, doxorubicin, and prednisone in patients with previously untreated diffuse large B-cell lymphoma. The European Medicines Agency’s Committee for…
These people needed new careers. They found them at coding boot camps
Alejandro Calzadilla, 36, worked as a freelance professional cellist in Quebec City for over a decade, frequently playing with the Quebec Symphony Orchestra and offering cello lessons. But when public health restrictions aimed at slowing the spread of COVID-19 dried up all his work in early 2020, Calzadilla decided it was…
SnowdropKCS services – Phase 3 Consulting
Sage’s SnowdropKCS software will be end of life from April 2022 and the system will no longer be available. Many businesses will be forced to look for an alternative solution. Phase 3 offers a wide range of SnowdropKCS consultancy services to help you manage the transition process smoothly and effectively….
google careers ADM
google data scientist certificate careers at google canada google applied jobs google hiring 2022 google ads specialist hiring hiring in google google company recruitment 2021 google frontend developer google reviewer job google philanthropy jobs machine learning developer google google bioinformatics jobs google android developer jobs google attorney jobs google pm…
TargetScanHuman 7.1
TargetScanHuman 7.1 * broadly conserved = conserved across most vertebrates, usually to zebrafish conserved = conserved across most mammals, but usually not beyond placental mammals TargetScan predicts biological targets of miRNAs by searching for the presence of conserved 8mer, 7mer, and 6mer sites that match the seed region of each…
BTG2 gene predicts poor outcome in PT-DLBCL
Introduction Primary testicular diffuse large B-cell lymphoma (PT-DLBCL) is a rare and aggressive form of mature B-cell lymphoma.1–3 PT-DLBCL was the most common type of testicular tumor in men aged over 60 and characterized by painless uni- or bilateral testicular masses with infrequent constitutional symptoms.4–6 PT-DLBCL shows significant extranodal tropism,…
Methodology for clinical genotyping of CYP2D6 and CYP2C19 | Dr Med
APA 6th Edition Carvalho Henriques, B., Buchner, A., Hu, X., Wang, Y., Yavorskyy, V., Wallace, K. … Aitchison, K. J. (2021). Methodology for clinical genotyping of CYP2D6 and CYP2C19. Translational Psychiatry, 11. (1). doi: 10.1038/s41398-021-01717-9 MLA 8th Edition Carvalho Henriques, Beatriz, et al. “Methodology for clinical genotyping of CYP2D6 and…
Extracellular circulating miRNAs as stress-related signature to search and rescue dogs
Study approval was provided by the Research Ethics Committee of the University of Perugia (report n.2018-21 of 11/12/2018) according to Italian Ministry of Health legislation18. All methods were carried out following relevant guidelines and regulations and the study was carried out in compliance with the ARRIVE guidelines. Informed consent is…
Exosomal microRNA-618 derived from mesenchymal stem cells attenuate the progression of hepatic fibrosis by targeting Smad4
Introduction Hepatic fibrosis (HF) is a pathological phenomenon produced in the process of long-term damage and repair in the liver [1,2]. During the formation of HF, hepatocytes are damaged by various factors, such as chronic liver disease, and excessive intake of alcohol, and secrete a variety of cytokines [3]. Subsequently,…
Effects of terfenadine and diphenhydramine on the CYP2D6 activity in healthy volunteers.
The aim of this study was to investigate the effects of two antihistaminic drugs, terfenadine and diphenhydramine on CYP2D6 activity by using debrisoquine as a model substrate. The study was carried out as an in vivo single-dose study in 12 young, healthy men. All volunteers had previously been identified as…
Axi-cel CAR-T significantly improves EFS among older patients with non-Hodgkin lymphoma
February 16, 2022 3 min read Source/Disclosures Published by: Source: van Meerten T, et al. Abstract PT02-1. Presented at: European Society for Blood and Marrow Transplantation-European Hematology Association 4th European CAR T-cell Meeting (virtual meeting); Feb. 10-12, 2022. Disclosures: van Meerten reports honoraria from Kite Pharma and…
Associate Operations Manager Job Opening in Houston, TX at NuProbe USA Inc.
Associate Operations Manager NuProbe USA is hiring one Associate Operations Manager for its Houston (TX) location. The successful candidate will have the opportunity to join the NuProbe family in the G&A Department reporting directly to the Director of Operations. Essential Job Duties and Responsibilities: Essential responsibilities and duties include, but…
ABCB1, ABCG2 and CYP2D6 polymorphism effects on disposition and response to long-acting risperidone | Dr Med
APA 6th Edition Ganoci, L., Trkulja, V., Živković, M., Božina, T., Šagud, M., Lovrić, M. & Božina, N. (2021). ABCB1, ABCG2 and CYP2D6 polymorphism effects on disposition and response to long-acting risperidone. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 104.. doi: 10.1016/j.pnpbp.2020.110042 MLA 8th Edition Ganoci, Lana, et al. “ABCB1, ABCG2…
Sr. Bioinformatics Scientist-Project Manager – 114267
#114267 Sr. Bioinformatics Scientist-Project Manager Filing Deadline: Mon 2/14/2022 UCSD Layoff from Career Appointment: Apply by 02/02/2022 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor. Special Selection Applicants: Apply by 02/14/2022. Eligible Special Selection clients should contact their Disability Counselor for assistance. The UCSD…
python – How can I fix the dash bio error: devtools cannot load source map dashbio@1.0.1 bundle.js.map?
I am implementing a website in Python with Django framework and using django-plotly-dash to display data. I am trying to use dash_bio’s IGV feature to display some chromosome data, but when I attempt to call the functionality, I receive the following errors and the callback that returns ‘dashbio.igv’ is unable…
Executive Search Firm – Recruitment Agenciespinpoint one
Our assignments are continuously exciting and relevant in this consistently challenging economy. our story A story that goes back to the 1st of May 1999 – “International Workers’ Day”as the world was nervous about the possible chaos of Y2K, we instead were confident about our business being an entrepreneurial business…
Convert DNAStringSet to a list of elements in R? (Error in seq[[1]][[“seq”]] : subscript out of bounds in R)
I have a bed file which contains DNA sequences information as follow: ** track name=”194″ description=”194 methylation (sites)” color=0,60,120 useScore=1 chr1 15864 15866 FALSE 894 + chr1 534241 534243 FALSE 921 – chr1 710096 710098 FALSE 729 + chr1 714176 714178 FALSE 12 – chr1 720864 720866 FALSE 988 -…
Postdoctoral Fellow – Plant Genomics & Bioinformatics – Fort Collins
Working Title Postdoctoral Fellow – Plant Genomics & Bioinformatics Position Location Fort Collins, CO Research Professional Position Yes Posting Number 202101543AP Position Type Admin Professional/ Research Professional Classification Title Postdoctoral Fellows Number of Vacancies Work Hours/Week 40 Proposed Annual Salary Range $50,000-$59,000. Salary is commensurate with experience and qualifications. Employee…
Cell-free DNA for the detection of emerging treatment failure in relapsed/ refractory multiple myeloma
Interrogation of cell-free DNA (cfDNA) represents an emerging approach to non-invasively estimate disease burden in multiple myeloma (MM). Here, we examined low-pass whole genome sequencing (LPWGS) of cfDNA for its predictive value in relapsed/ refractory MM (RRMM). We observed that cfDNA positivity, defined as ≥10% tumor fraction by LPWGS, was…
Time-course RNASeq of Camponotus floridanus forager and nurse ant brains indicate links between plasticity in the biological clock and behavioral division of labor | BMC Genomics
1. Sharma VK. Adaptive significance of circadian clocks. Chronobiol Int. 2003;20(6):901–19. PubMed Google Scholar 2. Paranjpe DA, Sharma VK. Evolution of temporal order in living organisms. J Circadian Rhythms. 2005;3(1):7. PubMed PubMed Central Google Scholar 3. Yerushalmi S, Green RM. Evidence for the adaptive significance of circadian rhythms. Ecol Lett….
how to make 2d rendering on directx 11 more faster – Graphics and GPU Programming
I make an editor for own game engine and I used for 2d rendering Direct2D but I wanted to render a directx texture on window in editor, I didn’t find convenient way to convert directx texture to direct2d bitmap. I decided to make own 2d render on directx 11 and…
CRISPR-Cas12a ribonucleoprotein-mediated gene editing in the plant pathogenic fungus Magnaporthe oryzae
. 2021 Dec 24;3(1):101072. doi: 10.1016/j.xpro.2021.101072. eCollection 2022 Mar 18. Affiliations Expand Affiliation 1 Department of Plant Pathology, Kansas State University, Manhattan, KS, USA. Free PMC article Item in Clipboard Jun Huang et al. STAR Protoc. 2021. Free PMC article Show details Display options Display options Format AbstractPubMedPMID . 2021 Dec…
Immune-related Prognostic Genes of ccRCC
Introduction Kidney cancer is one of the most commonly diagnosed tumors around the globe.1 According to the statistics from the World Health Organization, annually, there are more than 140,000 RCC-related deaths.2 ccRCC is the most typical subtype of kidney cancer and contributes to the majority of kidney cancer-related deaths.3,4 Until…
Relay Therapeutics Announces Dosing of First Patient in First-in-Human Trial of RLY-2608 and Initiation of Expansion Cohorts for First-In-Human Trial of RLY-4008
Doses first patient in first-in-human trial of RLY-2608, a pan-mutant and isoform-selective PI3Kα inhibitor Selects 70 mg once-daily dose for RLY-4008 andinitiates expansion cohorts in patients with FGFR2-altered solid tumors, including cholangiocarcinoma and breast cancer CAMBRIDGE, Mass., Jan. 04, 2022 (GLOBE NEWSWIRE) — Relay Therapeutics (Nasdaq: RLAY), a clinical-stage precision…
CIE-IIITH commences 14th cohort of deep-tech accelerator Avishkar
4 startups selected from over 150 applications Startups for Hiring solutions, Industrial manufacturing monitoring, and dispute resolution In 5 years of Avishkar, a total of 25 startups have been accelerated in AI, NLP, IoT, CV, robotics, and other emerging technologies Program includes Rs. 40 lakhs seed fund jointly with…
48 Postdoctoral and Academic Positions at The European Molecular Biology Laboratory, Germany
Postdoctoral and Academic Positions at The European Molecular Biology Laboratory (EMBL), a molecular biology research institution, Germany Scientific Officer – Protein Expression and Purification Core Facility Staff Member at EMBL Heidelberg Closes 14 February 2022 | Grading: Grading: 4, 5 or 6; depending on experience and qualifications (monthly salary starting from 3.1k – 3.8k EUR…
Postdoctoral Scholar – Bioinformatics/Biomedical Data Science
The University of Nevada, Reno (UNR) appreciates your interest in employment at our growing institution. We want your application process to go smoothly and quickly. Final applications must be submitted prior to the close of the recruitment. If you need assistance or have questions regarding the application process, please contact…
Brem Looks at Multiple Treatments for Patients With DLBCL
During a Targeted OncologyTM Case-Based Roundtable event, Elizabeth A. Brem, MD, an assistant professor in Division of Hematology/Oncology, Department of Medicine at UC Irvine Health in Los Angeles, CA, moderated a discussion about a 43-year-old woman with diffuse large B-cell lymphoma. Targeted Oncology™: What therapeutic options would you consider at…
Bioinformatics Analyst in Evanston, IL for Northwestern University
Details Posted: 23-Dec-21 Location: Evanston, Illinois Salary: Open Categories: Information Technology Staff/Administrative Department: MED-Center for Genetic MedSalary/Grade: EXS/8 Job Summary: Partners with clients to design, develop, implement and maintain business solutions regarding data management and analysis. This includes database administration, data consolidation, data analysis and management reporting. Utilizes software to…
Bioinformatics Core Facility staff position at IMB in Mainz, Germany
www.imb.de/jobs/jobdetail/bioinformatician Bioinformatician (m/f/d) (#CFBIO17) IMB (www.imb.de) is a research centre on the campus of Mainz University, Germany. It is generously funded by the Boehringer Ingelheim Foundation and the state of Rhineland-Palatinate. Our research focuses on the biology of the cell nucleus and ranges from the molecular level to organismic, systems…
Tafasitamab and Lenalidomide Combo Yields Higher OS vs Standard Options in Relapsed/Refractory DLBCL
Treatment with tafasitamab (Monjuvi) and lenalidomide (Revlimid) provided an overall survival (OS) benefit vs standard options in a population of patients with autologous stem cell transplant (ASCT)–ineligible relapsed/refractory diffuse large B-cell lymphoma (DLBCL), according to findings from an expanded analysis of RE-MIND2 study (NCT04697160) that was presented at the 2021…
Bristol Myers Squibb’s Breyanzi (lisocabtagene maraleucel) Significantly Improves Outcomes, Showing Superiority Over 20-Year Standard of Care in Second-Line Relapsed or Refractory Large B-cell Lymphoma Based on TRANSFORM Study Results
PRINCETON, N.J.–(BUSINESS WIRE)–Bristol Myers Squibb (NYSE: BMY) today announced the first disclosure of results from a prespecified interim analysis of the pivotal TRANSFORM study, a global, randomized, multicenter, Phase 3 study evaluating Breyanzi (lisocabtagene maraleucel; liso-cel), a CD19-directed chimeric antigen receptor (CAR) T cell therapy, as a second-line treatment in…
Liso-Cel Yields EFS Benefit as Second-line Therapy in LBCL
The phase 3 TRANSFORM study (NCT03575351) showed that patients with relapsed or refractory large B-cell lymphoma (LBCL) had a clinically meaningful improvement in event-free survival (EFS) compared with the standard of care (SOC) when treated with liscocabtagene maraleucel (liso-cel), according to prespecified interim results that were presented at the 2021…
Liso-cel significantly improves outcomes in second-line DLBCL
December 11, 2021 2 min read Source/Disclosures Published by: Source: Kamdar M, et al. Abstract 91. Presented at: ASH Annual Meeting and Exposition; Dec. 11-14, 2021. Disclosures: Kamdar reports consultant/advisory or speakers bureau roles with AbbVie, Adaptive Biotechnologies, ADC Therapeutics, AstraZeneca, Bristol Myers Squibb, Celgene, Genentech, Karyopharm…
EFS improvement with axi-cel CAR-T a ‘breakthrough’ in second-line treatment of DLBCL
December 11, 2021 3 min read Source/Disclosures Published by: Source: Locke FL, et al. Abstract 2. Presented at: ASH Annual Meeting and Exposition; Dec. 11-14, 2021. Disclosures: Kite Pharma sponsored this study. Leslie reports advisory board, consultant or speakers bureau roles with AbbVie, AstraZeneca, BeiGene, Celgene/Bristol Myers…
Tafasitamab/Lenalidomide Improves OS Over Other Options in Retrospective Relapsed/Refractory DLBCL
The combination of tafasitamab (Monjuvi) and lenalidomide (Revlimid) prolonged median overall survival (OS) compared with other standard options for autologous stem cell transplant (ASCT)-ineligible patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL), according to a closely matched expanded analysis of the observational, retrospective RE-MIND2 (NCT04697160) study presented at the…
Bioinformatics Librarian job with University of Pennsylvania
Bioinformatics Librarian University Overview The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that…
The Evolving Treatment Landscape of Cholangiocarcinoma
Recent genomic profiling studies revealed that approximately 40% of patients with biliary tract cancers harbor actionable genomic mutations. The advances in the understanding and characterization of biliary tract cancers (BTCs), particularly intrahepatic cholangiocarcinoma (iCCA), and genomic profiling over the past decade have led to a rapid expansion of available treatment…
Director of Bioinformatics Research Job Opening in Hudson, FL at M2GEN
Director of Bioinformatics Research Location: Remote Status: Full-time ExemptReports to: VP Bioinformatics & BiostatisticsDirect Reports: Build and lead a team consisting of bioinformatics research scientists that support internal business development client engagements, as well as, external academic partner research projects and biopharma sponsored bioinformatics services Who we are M2GEN is…
Frontiers | The cGAS-STING Pathway: A Promising Immunotherapy Target
Introduction Invaded by exogenous or endogenous pathogens, the host immune system will be activated accordingly to resist harm and maintain homeostasis, which includes innate immunity and adaptive immunity. As the first line of host immune defense, innate immunity plays a critical role in recognizing extracellular and intracellular pathogens (1, 2)….
Role Of Mitochondrial DNA Copy Number In Incident Cardiovascular Diseases And The Association Between Cardiovascular Disease And Type 2 Diabetes: A Follow-up Study On Middle-aged Women
Atherosclerosis. 2021 Dec 1:S0021-9150(21)01448-9. doi: 10.1016/j.atherosclerosis.2021.11.020. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Mitochondrial DNA copy number (mtDNA-CN) is a surrogate biomarker of mitochondrial dysfunction and is associated with type 2 diabetes (T2D) and cardiovascular disease (CVD). However, despite being associated with both CVD and T2D, it is not known what…
Identification of lipid metabolism-associated gene signature
Background Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer. Despite the dramatic improvement in breast cancer prognosis due to recent therapeutic advances, such as more effective adjuvant and neo-adjuvant chemotherapies, together with more radical and safer surgery, advances in early diagnosis and treatment over the…
Genotype distribution and prevalence of human papillomavirus
Introduction Cervical cancer (CC) is the second most deadly disease among women in the world and is the leading cause of death from cancer.1 In 2018, there were 570,000 new diseases and 311,000 deaths worldwide.2 Viral infections contribute to 15–20% of all cancers, and several viruses play an important role…
National Centre For Disease Control Recruitment 2021 – Bioinformatics Specialist Government jobs in Delhi
National Centre For Disease Control recruiting Bioinformatics Specialist Experienced(1 to 3 Years) candidates candidates nearby Delhi.National Centre For Disease Control vacancies for Bioinformatics Specialist is recruited through Written-test, Face to Face Interview etc. National Centre For Disease Control Company recruits a lot of Experienced(1 to 3 Years) candidates candidates every…
SomaLogic hiring Bioinformatics Scientist I – R Developer in Colorado, United States
Position SummarySomaLogic was founded in 2000 with the goal of improving the well-being and quality of life of every individual by transforming how diseases were detected, diagnosed and managed. Building on decades of aptamer research, SomaLogic scientists developed a ground-breaking proteomics technology that overcomes the significant challenges of existing protein…
Medical Coding job -Biomedical, Biotechnology, Microbiology, Bioinformatics, Biochemistry Freshers Job For 0-3 Year Exp In I Skills Solutions Chennai, Coimbatore – 4205536
Medical Coding Job for Freshers: (2016 to 2021) Passed out Direct / Work from Home Ct HR Gomathy – 8428080909 Job Description: Position : Medical Coder Medical Coding is the process of converting Verbal Descriptions into numeric or alpha numeric by using ICD 10-CM, CPT & HCPCS. Requirement: knowledge in…
IRE combined with toripalimab versus IRE alone for LAPC
Introduction Pancreatic ductal adenocarcinoma (PDAC) is a lethal gastrointestinal disease with increasing morbidity, which also has a growing impact on cancer-specific mortality worldwide.1 Nearly 40% of all PDAC cases are localized to the pancreas and characterized with the involvement of major vascular structures, leading to unresectable disease without metastases detected…
Research Fellow – Statistical Genetics, Genetic Epidemiology, Bioinformatics at UCL
Fixed Term- The post is funded until 31 October 2024 in the first instance. The appointment will be on UCL Grade 7. The salary range will be £36,770 – £43,200 per annum , inclusive of London Allowance. Duties and Responsibilities The postholder will be based at the UCL Institute of…
Medical Coding Openings For Bioinformatics, Biochemistry,Biochemist Graduates
SkillSet: “medical coder”, bioinforamtics, pharma, “biomedical engineers”, pharmacist. Position: Medical Coder HR Mythili- 9566284629 Job Description:Medical Coding is the process of conversion of text information related to healthcare services into numeric Diagnosis (Medical Problems) and Procedure (Treatments) Codes using ICD-10 CM and CPT code books. Requirement: knowledge in Anatomy and…
Kaggle Training
Listing Results Kaggle training Learn Python, Data Viz, Pandas & More Tutorials Kaggle Learn Kaggle.com All Courses 8 hours agoPython Learn the most important language for data science. Intro to Machine Learning Learn the core ideas in machine learning, and build your first models. Intermediate Machine Learning Handle missing values,…
Bioinformatics Scientist Job Opening in Iowa City, IA at Jones Microbiology Institute Inc
Description: JMI Laboratories is a mid-sized company based in North Liberty, IA. A global leader for twenty years in anti-infectives research, JMI monitors annual changes in antibiotic resistance patterns through the SENTRY Antimicrobial Surveillance Program, serves as a clinical and reference laboratory in support of new drug development, and conducts…
Identification of Prognosis-Associated Biomarkers in Thyroid Carcinoma
Introduction Thyroid cancer (TC) is a common endocrine malignancy with a rapidly increasing incidence worldwide, and the estimated new cases and deaths are notably higher in women than in men.1 Papillary thyroid carcinoma (PTC) is identified as the most common pathological type of TC, and accounts for approximately 80–85% of…
The Current Molecular Treatment Landscape of Advanced Colorectal Cancer and Need for the COLOMATE Platform
Next-Generation Sequencing Utilizing Tumor Tissue and/or Blood The identification of actionable genomic alterations in tumors such as mCRC was once performed by Sanger DNA sequencing of tumor DNA that was extracted from fixed paraffin-embedded tumor tissue, but this has now been replaced by next-generation sequencing (NGS), which allows for larger-scale…
Associate Director/Director, Bioinformatics/Computational Biology Job Opening in Cambridge, MA at ImmuneID
ImmuneID aims to revolutionize therapeutic drug development by mapping immune disease drivers through our unique, high-throughput and unbiased platforms. We are seeking an Associate Director/Director, Bioinformatics/Computational Biology to join our growing team of passionate researchers focused on unlocking human immunology. Scope As a key member of the Science team, the…
Bioinformatics Scientist 2 (Internal Only)
Job Summary We have an exciting opportunity in our US office for an experienced bioinformatician who is interested in working at the forefront of the gene editing (CRISPR knock-out, HDR, base editing) and gene modulation (CRISPRa, CRISPRi, RNAi) fields. As a Bioinformatics Scientist 2, you will have the opportunity to…
Oxford Nanopore’s London IPO Filing Could Top $5.5 Billion in Value
A scientist uses a pipette to place a sample on a GridION in an Oxford Nanopore lab. Oxford Nanopore, the pioneer developer of DNA/RNA nanopore sensing tools that include its pocket-sized MinION DNA/RNA sequencer, has disclosed plans for an initial public offering that could value the company at a reported…
Bioinformatics Analyst – REMOTE – 2395 at Connexion Systems & Engineering
Connexion’s mission is to provide “best in class” services to job seekers. We strive to achieve excellence in job placement, staffing, and recruiting services, while treating candidates with the professionalism and respect they deserve. Title: Bioinformatics Analyst Hiring Organization: Connexion Systems & Engineering Compensation, Benefits, and Employment Type Duration: 6+…
Lecturer in Bioinformatics with focus area AI in Drug Discovery – Uppsala University – Bioinformatik – job portal
Skip to main content Denna sida på svenska Published: 2021-09-09 Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all…
Comparative genomic analysis of Methanimicrococcus blatticola provides insights into host adaptation in archaea and the evolution of methanogenesis
1. Hackstein JH, Stumm CK. Methane production in terrestrial arthropods. Proc Natl Acad Sci USA. 1994;91:5441–5. CAS PubMed PubMed Central Article Google Scholar 2. Hackstein JHP, van Alen TA. Fecal methanogens and vertebrate evolution. Evolution. 1996;50:559–72. PubMed Article PubMed Central Google Scholar 3. Borrel G, McCann A, Deane J, Neto…
Gene expression profiling of contralateral dorsal root gangl
Introduction Mirror-image pain (MIP) is a mysterious pain phenomenon which is accompanied with many clinical pain conditions.1 MIP develops from the healthy body region which is contralateral to the actual injured site.1–3 MIP is typically characterized by increased mechanical hypersensitivity on the uninjured mirror-image body side.4 It can be triggered…
Senior Bioinformatics Data Engineer – GRAIL
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale…
BIOINFORMATICS PROGRAMMER
UC San Diego Health BIOINFORMATICS PROGRAMMER Filing Deadline: Thu 9/16/2021, thereafter Open Until filled Salary Range: Commensurate with Experience The UCSD Hemophilia and Thrombosis Treatment Center has a wide-ranging clinical, translational and basic research program, involving genomic and proteomic analysis, in the field of thrombosis and hemostasis. This role involves…
Bioinformatics AMD Manager | Government Jobs
Effective date: June 29, 2021 Contents 1.Introduction 2.About this Policy 3.Information We Collect About You 4.Our Use of Your Information 5.Information We Disclose 6.Your Data Rights 7.Retention and Removal 8.Cookies and similar Tracking Technologies; “Do Not Track” 9.Information Security and Integrity 10.Information on Children 11.Your California Privacy Rights 12.Your Nevada…
Analysis of the Prognostic Significance of Circulating Tumor DNA in Metastatic Castrate Resistant Prostate Cancer
This article was originally published here Clin Genitourin Cancer. 2021 Jul 31:S1558-7673(21)00151-8. doi: 10.1016/j.clgc.2021.07.012. Online ahead of print. ABSTRACT BACKGROUND: There has been considerable interest in ctDNA next generation sequencing platforms to assess genomic alterations in mCRPC given its accessibility and identification of temporal genomic data. PATIENTSAND METHODS: In this…
PROJECT POLICY ANL 2 (Bioinformatics Core Project and Workshop Coordinator) in Davis, CA for University of California Davis
PROJECT POLICY ANL 2 (Bioinformatics Core Project and Workshop Coordinator) Job Summary DEPARTMENT DESCRIPTION The UC Davis Genome Center is a campus-wide initiative integrating experimental and computational approaches to address key problems at the forefront of genomics. The Bioinformatics core provides expertise and infrastructure to carry out complex acquisition, curation…
Adjunct Faculty: Bioinformatics – Intro to Bioinformatics, Practical Computer Concepts for job with Johns Hopkins University
Johns Hopkins University Advanced Academic Programs Biotechnology Program Adjunct Faculty: Bioinformatics (Introduction to Bioinformatics, Practical Computer Concepts for Bioinformatics, Metagenomics) Institution Description: The Advanced Academic Programs (AAP) is a division of the Krieger School of Arts and Sciences at the Johns Hopkins University (JHU). As the nation’s oldest and one…
Predicting and characterizing a cancer dependency map of tumors with deep learning
INTRODUCTION The development of novel cancer therapies requires knowledge of specific biological pathways to target individual tumors and eradicate cancer cells. Toward this goal, the landscape of genetic vulnerabilities of cancer, or the cancer dependency map, is being systematically profiled. Using RNA interference (RNAi) loss-of-function screens, Marcotte et al. (1),…
How do I start clue GO in R using the cytoscape REST API?
How do I start clue GO in R using the cytoscape REST API? 0 Hi there, I am trying to connect to open the Clue GO application in R using cytoscape REST API. I have the following code: port.number = 1234 host.address <- “localhost” cytoscape.base.url = paste(“http://”,host.address,”:”, toString(port.number), “/v3.11.1″, sep=””)…
Jr and Sr bioinformatician profiles for immunotherapy design in cancer patients (BELGIUM)
Junior Bioinformatician (data scientist) Are you passionate about actively helping in implementing new personalized cancer treatments, alongside accomplished biotech experts? Are you looking for an ambitious new project to test and grow your knowledge? Who are we? myNEO is a Belgian bio-tech company in Ghent, focused on identifying, exploring and…
Controlling Banana Xanthomonas Wilt Disease in East Africa
© Olena Danileiko Experts Leena Tripathi, Jaindra Nath Tripathi and Richard Goodman, provide a compelling analysis of controlling Banana Xanthomonas Wilt Disease in East Africa By way of an introduction, banana (Musa spp.) is one of the most common fruits worldwide. However, it is an important staple crop in the…
EMBL Archive and Records Manager at European Molecular Biology Laboratory (EMBL)
About the team/job We are seeking two experienced information professionals with expertise in archiving and records management. These posts will be based in the EMBL Office for Scientific Information Management, a new office with responsibility for the EMBL library, open science support, and EMBL archive and records. These two posts…
Rancho BioSciences hiring RShiny Scientist/Bioinformatics in San Diego, California, United States
Rancho Biosciences is seeking a RShiny bioinformatics expert to provide support for a range of projects which include the development of R-Shiny applications, managing NGS data associated with clinical and metadata organization. Work from home while supporting high impact pharmaceutical, academic and institutional science programs. We are specifically looking for…
Medical coding jobs – Microbiology Biotchnology Bioinformatics Fresher Job For 0-3 Year Exp In I Skills Solutions Madurai, Trichy – 2846442
Medical Coding Job for Freshers : (2017 to 2021) Passed out Direct / Work from Home Ct HR Gomathy – 8428080909 Job Description: Position : Medical Coder Medical Coding is the process of converting Verbal Descriptions into numeric or alpha numeric by using ICD 10-CM, CPT & HCPCS. Requirement: knowledge…
Genomics Data Scientist
Genomics Data Scientist – 93419 Organization: JG-Joint Genome Institute Lawrence Berkeley National Lab (LBL, lbl.gov/) Joint Genome Institute (JGI, jgi.doe.gov/) Division has an opening for a Genomics Data Scientist. This is an exciting opportunity for applying your data science expertise in genomics to solve the most challenging energy and environmental…