Tag: HRS

Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant

Subjects Normal breast and tumor samples were obtained with the written informed consent from donors and appropriate approval from local ethical committees, with the detailed information described in the respective original publications: normal tissue9, METABRIC14, TCGA35. Differential allelic expression analysis DNA and total RNA from 64 samples of normal breast…

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Frontiers | COMMD2 Upregulation Mediated by an ncRNA Axis Correlates With an Unfavorable Prognosis and Tumor Immune Infiltration in Liver Hepatocellular Carcinoma

Introduction Liver hepatocellular carcinoma (LIHC) is the most common type of primary cancer in the liver and third leading cause of cancer-related mortality worldwide (1). Although substantial improvements have been made in LIHC therapy, particularly in molecular targeted therapy and immunotherapy (2, 3), the 5-year survival rate of LIHC is…

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Head of Bioinformatics job in Chesterford

Job Information Role Overview HRS are recruiting for a head of Bioinformatics to join an innovative Biotech company based in the Cambridge area. Having grown rapidly and with two oncological products progressing into clinical trials, this position will be key to maintaining the companies competitiveness, Leading a well-established team working…

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Innovative site-specific anti-HER2 antibody-drug conjugate

Introduction Antibody-drug conjugates (ADCs) have been studied for decades as a promising cancer treatment. As compared to conventional chemotherapy, ADCs have a larger therapeutic window because of their ability to target antigen-expressing tumor cells.1 As ADC drug development technology continues to evolve, several ADC drugs are being introduced to the…

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Need help from a math quant. Must know R/Rstudio – Freelance Job in AI & Machine Learning – Less than 30 hrs/week – undefined

Part 1) Need help analyzing data and coming up with the most profitable portfolio possible Part 2) I need to get some simulations running as fast as possible. I have the code completely finished so I just need suggestions on how to make it better. Video available if needed. I…

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Galaxy Genome [Space Sim] HACK/MOD Unlocked All vVaries with device

Download Galaxy Genome [Space Sim] Mod Varies with device for android apk & iphone ios 4.4 and up Galaxy Genome is an open world sci-fi space simulator. You can upgrade your ship and customize each component as you hunt, explore, fight, mine, smuggle, trade and survive in a brutal galaxy….

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Identification of a four-gene signature & PTC.

Introduction Thyroid carcinoma (THCA) is the most common type of endocrine malignancy and its incidence is increasing.1 Based on its histopathological characteristics, thyroid carcinoma can be classified into multiple subtypes, such as papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, and anaplastic thyroid carcinoma.2 PTC is the most common subtype of…

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Harvard University hiring Bioinformatics Engineer in Boston, Massachusetts, United States

Job-Specific ResponsibilitiesWe are looking for a motivated bioinformatics engineer to join the Department of Biomedical Informatics at Harvard Medical School, to build platforms for genome analysis. Genome sequencing is becoming a routine approach for diagnosing genetic diseases. As the number of patients referred to genetic screening is increasing, there is…

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computeMatrix in deeptool is Running with no result

computeMatrix in deeptool is Running with no result 0 Hi All, I wonder if someone can help me in explaining what to input on the -R <bed file> argument of the code below? computeMatrix scale-regions -S <bigwig file(s)> -R <bed file> -b 1000 what I did for example, I download…

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Ethnic Diversity of DPD activity and the DPYD Gene

Plain Language Summary Fluoropyrimidine (FP; 5-FU, capecitabine) is a common chemotherapy used to treat many different cancers, including cancer of the colon and rectum, upper digestive tract, breast and head and neck. Cancer patients who receive FP chemotherapy are at risk of developing severe side effects from their treatment. A…

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r – ggplot: Try to plot boxplots with geom_rect on its background, but keep having error with object “variable” not found

I was almost desperate with this error after working on this for 4 hrs, googled and looked from past posts already. Here is my data structure: str(tcga_exp) ‘data.frame’: 11775 obs. of 5 variables: $ cohort: chr “BRCA-Basal.Tumor” “BRCA-LumA.Tumor” “BRCA-LumB.Tumor” “BRCA-LumA.Tumor” … $ exp : num 6.35 5.54 6.56 5.05 5.98…

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Bioinformatics and computational scientist to analyze genomics data – Freelance Job in Quantitative Analysis – Less than 30 hrs/week – More than 6 months

Weare looking for an experienced and motivated data scientist with expertise in computational biology, genomics and statistics. We are considering both full time and part time positions with virtual/remote work options. This is what we need:Strong expertise in gene expression analysis including RNAseq, sc-RNAseq, microarray technologies.Analysis if genetic variant dataMachine…

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Bioinformatics Scientist – reed.co.uk

We are currently looking for a Bioinformatics Scientist to join a leading biotech company based in the Cambridge area. As the Bioinformatics Scientist you will drive the development of computational tools and perform omics data analysis to support target identification and therapeutics development platforms KEY DUTIES AND RESPONSIBILITIES: Your duties…

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Standard Bioinformatics Analysis of RNAseq data (DGE, Pathway Enrichment, Network analysis) – Freelance Job in Quantitative Analysis – Less than 30 hrs/week – Less than 1 month

We are looking for bioinformatics help to analyze specific data sets available from GEO / NCBI using standard bioinformatics analysis pipeline We will provide the study, design and data We will ask you to create a standard bioanalytical report that will include :– Differential gene expression, clustering – Pathway enrichment/analysis–…

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Bioinformatician job with Clemson University – Center for Human Genetics

The Clemson University Center for Human Genetics and the Greenwood Genetic Center have been awarded a five year Phase I Center of Biomedical Research Excellence (COBRE) in Human Genetics grant to understand the genetic, genomic, and epigenetic mechanisms by which molecular genetic variation affects transcriptional and other molecular networks in…

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Research Scientist- Bioinformatics & Computational Biology

Position Description: Research Scientist- Bioinformatics & Computational Biology, position in Christopher S. Bond Life Science Center, University of Missouri-Columbia. Potential Start Date: November 1, 2021 Duration: 24-month initial appointment, renewable afterwards Minimum Qualifications: Applicant must have a PhD degree in Computer Science, Bioinformatics, or related field. Strong publication record, especially…

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PROJECT POLICY ANL 2 (Bioinformatics Core Project and Workshop Coordinator) in Davis, CA for University of California Davis

PROJECT POLICY ANL 2 (Bioinformatics Core Project and Workshop Coordinator) Job Summary DEPARTMENT DESCRIPTION The UC Davis Genome Center is a campus-wide initiative integrating experimental and computational approaches to address key problems at the forefront of genomics. The Bioinformatics core provides expertise and infrastructure to carry out complex acquisition, curation…

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Helicobacter pylori in Pakistan | IDR

Introduction Helicobacter pylori, an infectious agent of human chronic active gastritis and also associated with other gastric ailments such as peptic ulcer, gastric cancer, and mucosa-associated lymphoid tissue lymphoma.1 Clarithromycin is considered the best option among other antibiotics for the management of this bacterial infection.2 However, increasing resistance against this…

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Integrated bioinformatics analysis to identify abnormal CC

Introduction In recent years, the morbidity and mortality of colon cancer have increased rapidly, both being ranked fourth worldwide. Although surgery-based comprehensive treatments improve the prognosis of colon cancer, because of the lack of available means for early diagnosis, the mortality level remains high for patients with advanced-stage cancer. The…

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Vaccines are not ‘trial’ or experimental

Tobago Kinnesha George 6 Hrs Ago PAHO/WHO Country Representative, Dr Erica Wheeler. Photo courtesy PAHO. – Pan American Health Organization/World Health Organization (PAHO/WHO) country representative Dr Erica Wheeler has said WHO-approved covid19 vaccines are not trial vaccines. As the vaccine hesitancy continues, Wheeler, speaking at Thursday’s THA Division of Health,…

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