Tag: IP-MS

Any one familiar with IP-MS data analysis?

Any one familiar with IP-MS data analysis? 0 I have a dataset from an IP-MS experiment. In the excel, I have the spectral counts for “pre clear” (as background) in addition to the spectral counts for prey proteins. I assume to perform DE analysis, I need to substract “pre-clear” counts…

Continue Reading Any one familiar with IP-MS data analysis?

Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy

Rab8A and Rab41 are required for xenophagy of GAS For comprehensive screening of Rab GTPases involved in xenophagy against GAS infection, we first knocked down the expression of Rab GTPases in HeLa cells. We examined bacterial survival in cells at 6 h post-infection (hpi) compared with that at 2 hpi because…

Continue Reading Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy

Grant-Funded Researcher (B) job with UNIVERSITY OF ADELAIDE

(Level A) $75,888 to $102,040 or  (Level B) $107,276 to $126,894 per annum plus an employer contribution of 17% superannuation applies. Fixed term, full time position available for 1 year with a possibility to extend. A postdoctoral research fellow position is available to work Dr Qi Zhang, who is establishing her…

Continue Reading Grant-Funded Researcher (B) job with UNIVERSITY OF ADELAIDE

Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming

Background: Thymidine kinase 1 (TK1) is a cell cycle-dependent kinase that catalyzes the addition of a gamma-phosphate group to thymidine. The protumorigenic role of TK1 has been reported in various malignancies. However, the role of TK1 in skin cutaneous melanoma (SKCM) remains unclear. This study aimed to explore the molecular…

Continue Reading Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming