Tag: IRI

Integrated Resources, Inc ( IRI ) hiring Bioinformatics Scientist – III (Senior) Bioinformatics Scientist – III (Senior) in South San Francisco, California, United States

We are seeking a motivated Computational Biologist with hands on experience to join our team dedicated to advancing our Cardiometabolic Disease (CMD) portfolio. As a scientist in CMD, you will:Be part of creative and enthusiastic teams working on target identification and validation (TIDVAL) for heart failure, NASH, fibrosis, inflammation, obesity,…

Continue Reading Integrated Resources, Inc ( IRI ) hiring Bioinformatics Scientist – III (Senior) Bioinformatics Scientist – III (Senior) in South San Francisco, California, United States

cGAS-STING signaling pathway promotes hypoxia-induced renal fibrosis by regulating PFKFB3-mediated glycolysis

Hypoxia has long been considered to play an active role in the progression of fibrosis in chronic kidney disease, but its specific mechanism is not fully understood. The stimulator of interferon genes (STING) has been a research hotspot in the fields of tumor, immunity, and infection in recent years, and…

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Integrated Resources, Inc ( IRI ) hiring Computational Biologist/Bioinformatician in Mississauga, Ontario, Canada

This contract position provides the opportunity to implement and deliver bioinformatics tools for a wide range of applications working with proteomics. The candidate will join a team focused on infrastructure developments for proteomics and collaboration with many research groups in Genentech, working with both bioinformatics and bench biology teams. Responsibilities…

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Genomic characteristics of a multidrug-resistant E. coli

Introduction Escherichia coli, a member of the Enterobacterales family, is a common opportunistic pathogen that can cause various infectious illnesses, including urinary tract infections (UTIs) and other infections acquired in the community.1,2 The presence of carbapenemases in E. coli poses a serious threat to public health. These carbapenemase genes may…

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Integrated Resources, Inc ( IRI ) hiring Associate Scientist-iPSCs in Cambridge, Massachusetts, United States

Job Description: Senior Associate Scientist, Neuroscience Discovery Biology(100% on-site) seeks a highly motivated Associate Scientist to join the Stem Cell and Disease Modeling team in the Neuroscience Thematic Research Center (NTRC). The newly developed NTRC is dedicated to the discovery of new treatments for neurodegenerative diseases such as Alzheimers and…

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DUSP1 Protects Against Ischemia-Induced Mitochondrial Injury Through Stabilizing mtDNA Via Interaction with JNK by Lang Shi, Hongchu Zha, Zhou Pan, Yao Xia, Huiming Li, Hua Huang, Ruchi Yue, Zhixia Song, Jiefu Zhu :: SSRN

Preprints with The Lancet is part of SSRN´s First Look, a place where journals identify content of interest prior to publication. Authors have opted in at submission to The Lancet family of journals to post their preprints on Preprints with The Lancet. The usual SSRN checks and a Lancet-specific check…

Continue Reading DUSP1 Protects Against Ischemia-Induced Mitochondrial Injury Through Stabilizing mtDNA Via Interaction with JNK by Lang Shi, Hongchu Zha, Zhou Pan, Yao Xia, Huiming Li, Hua Huang, Ruchi Yue, Zhixia Song, Jiefu Zhu :: SSRN

Integrated Resources, Inc ( IRI ) hiring Bioinformatics Scientist in Waltham, Massachusetts, United States

Description: Contract Worker, Bioinformatics, Cell and Genome Engineering, Genomic Medicine Unit We are seeking a contract bioinformatics scientist to be part of a team focused on cell and genome engineering in the Genomic Medicine Unit. The successful candidate will play an important role to support the activities around various projects…

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rRNA processing [GO_0006364] | Virtual Fly Brain

Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. Note This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewer Open rRNA processing…

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PM Modi holds high-level review meeting, calls to enhance genome sequencing

Covid cases in India: PM Modi holds high-level review meeting, calls to enhance genome sequencing (Photo: PIB) Covid cases in India: Prime Minister Narendra Modi emphasised on Wednesday that COVID-19 is “far from over” as he chaired a high-level meeting and called for maintaining vigil and precaution amid a spike…

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NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury

Altered NAD+ metabolism is prominent in diseased human kidneys We collected human kidney samples from healthy controls (n = 25) and patients with diabetic or hypertensive KD, defined as estimated glomerular filtration rate (eGFR) less than 60 ml min−1 per 1.73 m2 and kidney fibrosis (n = 25) (Fig. 1a). The mean eGFR values were 95 ml min−1 per 1.73 m2 (healthy…

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Integrated Resources, Inc ( IRI ) hiring Bioinformatics Scientist in Mississauga, Ontario, Canada

Client Sequencing Solutions (RSS), a business within Client Diagnostics, is focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Bioinformatics Scientist to support assay development efforts. In this role, you will…

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Gene Editing with CRISPR Can Repair Heart Attack Damage

According to a recent Genetic Literacy Project article, researchers from the University of Texas Southwestern Medical Center have developed a new CRISPR gene editing therapy that could help treat heart disease and repair damaged tissue immediately after a heart attack. The team used a mouse model to study their new…

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openapi-sampler | npm trends

openapi-sampler Tool for generation samples based on OpenAPI payload/response schema Features Deterministic (given a particular input, will always produce the same output) Supports compound keywords: allOf, oneOf, anyOf, if/then/else Supports additionalProperties with x-additionalPropertiesName Uses const, examples, enum and default where possible – in this order Good array support: supports contains,…

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Download “Epigenetic Memory” Phenomenon in Induced Pluripotent Stem Cells. PDF

reVIeWS “Epigenetic Memory” Phenomenon in Induced Pluripotent Stem Cells E.A. Vaskova1,2,3, A.E. Stekleneva1,2,3, S.P. Medvedev1,2,3, S.M. Zakian1,2,3,* 1Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, prosp. Akad. Lavrentyeva, 10, Novosibirsk, Russia, 630090 2Meshalkin State Research Institute of Circulation Pathology, Rechkunovskaya Str., 15, Novosibirsk, Russia, 630055 3Institute of…

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Integrated Resources, Inc ( IRI ) hiring Bioinformatics Data Scientist in Mississauga, Ontario, Canada

Location: Mississauga, ON Duration: 12+ Months Who We Are Looking ForWe are looking for an experienced Bioinformatics Data Scientist, with a proven track record of generating insights and building predictive models from biological data.For this position, we will consider applicants focused on Data Science applied to biological data with 3…

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