Tag: junk DNA
As expected, wine grapes found to have high deleterious genetic burden
A region containing a Fer-like gene was predicted to have introgressed from the EU and under selection. (A) A cluster of the malectin/receptor-like protein kinase domain was observed around the introgressed region. The malectin domain is represented by blue boxes. The red boxes indicate the CDS of the candidate Fer-like…
SickKids scientists shine light on the complex genetics that underlie blood pressure regulation
Scientists at The Hospital for Sick Children (SickKids) are delving deep into the non-coding genome to unravel the complex genetics that underlie blood pressure regulation and hypertension (high blood pressure) – the leading cause of cardiovascular disease affecting 1.25 billion people worldwide. While the human genome comprises coding and non-coding…
Molecular Explanation For How One Woman Doesn’t Feel Pain And Heals Rapidly
Jo Cameron is a woman who doesn’t feel pain but is also spared the usual consequences, thanks to rare mutations. She also experiences less anxiety or fear than other people. A study of the molecular basis of her condition could yield medical benefits for the rest of us. Not feeling pain…
LincRNA discovery could lead to targeted treatments
Our genetic code includes more than 15,000 specific sections that can be made into molecules called lincRNAs. Some of these sections can occur in coiled-up sections of our genome called topologically associating domains, or TADs. LincRNAs derived from TADs appear to act as markers indicating the specific kind of tissue…
Keyword: ncrna
Once considered unimportant “junk DNA,” scientists have learned that non-coding RNA (ncRNA) — RNA molecules that do not translate into proteins — play a crucial role in cellular function. Mutations in ncRNA are associated with a number of conditions, such as cancer, autism, and Alzheimer’s disease. Now, through the use…
Do We Really Need All This Junk DNA? Israeli Study Says Yes
Why is ‘junk DNA’ not deleted from the original genome over millions of years of evolution? A bold new hypothesis developed by Tel Aviv University scientists offers a possible solution to the question of why neutral sequences, also known as “junk DNA,” continue to exist within the human genome for…
ChatGPT totally fails my one-question exam on Junk DNA
I was chatting with HJ Hornbeck and Dr Sarah yesterday, and we were tinkering with ChatGPT. We asked it for some simple medical advice, of the sort you might consult WebMD for, and Dr Sarah confirmed that it was close to what she would recommend. Then we asked it a…
Limit Fragment Duration Polymorphisms (RFLP) Style of DNA Profiling
Limit Fragment Duration Polymorphisms (RFLP) Style of DNA Profiling Conceptual The amazing strength regarding DNA technical as the a recognition product got lead a tremendous change in crimnal fairness . DNA studies legs is an information capital into forensic DNA typing neighborhood having informative data on popular quick tandem repeat…
The CRISPR Family Tree Holds a Multitude of Untapped Gene Editing Tools
Thanks to CRISPR, gene therapy and “designer babies” are now a reality. The gene editing Swiss army knife is one of the most impactful biomedical discoveries of the last decade. Now a new study suggests we’ve just begun dipping our toes into the CRISPR pond. CRISPR-Cas9 comes from lowly origins….
How Ancient Virus DNAs Are Guarding Marsupials From Modern Diseases
Incorporating viruses that previously endangered their life into their non-coding or “junk” DNA, marsupials have made friends with ancient adversaries. Researchers have discovered multiple lines of evidence suggesting that these sections of DNA guard against viruses that are identical to the originals – and that they do it extremely efficiently….
Ancient marsupial ‘junk DNA’ might be useful after all, scientists say
Viral fossils buried in DNA may protect against future virus infections, a new marsupial study suggests. Fossils of ancient viruses are preserved in the genomes of all animals, including humans, and have long been regarded as junk DNA. But are they truly junk, or do they actually serve a useful…
Quanta Magazine
Imagine the human genome as a string stretching out for the length of a football field, with all the genes that encode proteins clustered at the end near your feet. Take two big steps forward; all the protein information is now behind you. The human genome has three billion base…