Tag: LwaCas13a

Keynote Presentation: Engineered LwaCas13a with Enhanced Collateral Activity for Nucleic Acid Detection

Scientists Used Genetic Engineering to Change How High Cocaine Got Mice In Study ABSTRACT breaks down mind-bending scientific research, future tech, new discoveries, and major breakthroughs. Scientists have shown that the effects of cocaine in mice can be enhanced by microbes that live in the digestive tract, shedding light on…

Continue Reading Keynote Presentation: Engineered LwaCas13a with Enhanced Collateral Activity for Nucleic Acid Detection

Engineered LwaCas13a with enhanced collateral activity for nucleic acid detection

doi: 10.1038/s41589-022-01135-y. Online ahead of print. Jie Yang #  1 , Yang Song #  2   3 , Xiangyu Deng  4 , Jeffrey A Vanegas  1 , Zheng You  1 , Yuxuan Zhang  2   3 , Zhengyan Weng  2   3 , Lori Avery  5 , Kevin D Dieckhaus  6 , Advaith Peddi  4 , Yang Gao  7 , Yi Zhang  8…

Continue Reading Engineered LwaCas13a with enhanced collateral activity for nucleic acid detection

Frontiers | A Mutated Nme1Cas9 Is a Functional Alternative RNase to Both LwaCas13a and RfxCas13d in the Yeast S. cerevisiae

Introduction The clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) protein systems naturally exist in prokaryotes. They are RNA-mediated defense mechanisms to protect bacteria and archaea from invading nucleic acids (Barrangou et al., 2007). CRISPR–Cas systems are classified into two classes (1 and 2). Class 2 CRISPR–Cas require a single…

Continue Reading Frontiers | A Mutated Nme1Cas9 Is a Functional Alternative RNase to Both LwaCas13a and RfxCas13d in the Yeast S. cerevisiae

CASCADE: Naked eye-detection of SARS-CoV-2 using Cas13a and gold nanoparticles

This article was originally published here Anal Chim Acta. 2022 May 1;1205:339749. doi: 10.1016/j.aca.2022.339749. Epub 2022 Mar 22. ABSTRACT The COVID-19 pandemic has brought to light the need for fast and sensitive detection methods to prevent the spread of pathogens. The scientific community is making a great effort to design…

Continue Reading CASCADE: Naked eye-detection of SARS-CoV-2 using Cas13a and gold nanoparticles