Tag: Lynch

In a recent article published in the JAMA Network, researchers performed an observational study to determine the prevalence of germline genetic testing among all patients aged 20 years or older diagnosed with cancer between January 1, 2013, and March 31, 2019, in two United States (US), California and Georgia. Study:…

Shock EL, Holland M, Meyer-Dombard DA, Amend JP, Osburn GR, Fischer TP. Quantifying inorganic sources of geochemical energy in hydrothermal ecosystems, Yellowstone National Park, USA. Geochim Cosmochim Acta. 2010;74:4005–43. Article  CAS  Google Scholar  Hou W, Wang S, Dong H, Jiang H, Briggs BR, Peacock JP, et al. A comprehensive census…

Funding Support and Acknowledgements: COPDGene: The project described was supported by Award Number U01 HL089897 and Award Number U01 HL089856 from the National Heart, Lung, and Blood Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung,…

Depending on your point of view, artificial intelligence (AI) can create jobs, make life easier, and solve many global problems; or, it’s going to cause mass unemployment, take over the world, and enslave humanity.  In the life sciences space, AI is capable of tackling some of the biggest challenges when…

Avise J (2008) Clonality: the genetics, ecology, and evolution of sexual abstinence in vertebrate animals. Oxford University Press, USA Book  Google Scholar  Avise JC (2015) Evolutionary perspectives on clonal reproduction in vertebrate animals. Proc Natl Acad Sci USA 112(29):8867–8873 Article  CAS  PubMed  PubMed Central  Google Scholar  Andrews S (2010) FastQC:…

Flaxman JP, Smith DW, Mackenzie JS, Fraser JRE, Bass SP, Hueston L, et al. A comparison of the diseases caused by Ross River virus and Barmah Forest virus. Med J Aust. 1998;169:159–63. Article  Google Scholar  El-Hage CM, Bamford NJ, Gilkerson JR, Lynch SE. Ross River virus infection of horses: appraisal…

NEW YORK – The latest results from the BabySeq project suggest that unexpected, medically actionable variants in monogenic disease genes found by newborn genome screening can have clinical implications for both infants and their family members. “By screening apparently healthy newborns, entire families were alerted for the first time that…

Ten years ago, clinicians in a handful of hospitals around the United States began sequencing the genomes of apparently healthy babies, seeking to understand how the technology might turn up hidden genetic disorders that aren’t being caught by routine newborn blood testing. New research from one such trial suggests the…

Peona, V., Weissensteiner, M. H. & Suh, A. How complete are “complete” genome assemblies? An avian perspective. Mol. Ecol. Resour. 18, 1188–1195 (2018). Article  CAS  PubMed  Google Scholar  Peona, V. et al. Identifying the causes and consequences of assembly gaps using a multiplatform genome assembly of a bird-of-paradise. Mol. Ecol….

Introduction Tropical rainforests in the Amazon basin harbor the highest tree diversity on earth (Ter Steege et al., 2020). Most of this diversity is concentrated in a relatively small number of plant families, including Chrysobalanaceae, Fabaceae, Lauraceae, Lecythidaceae, Malvaceae (sensu lato), Myrtaceae, Rubiaceae, and Sapotaceae, that can comprise > 60%…

NVIDIA Corp. (NASDAQ:NVDA) Q1 2024 Earnings Conference Call May 24, 2023 5:00 PM ET Company Participants Simona Jankowski – VP, IR Colette Kress – EVP & CFO Jensen Huang – Co-Founder, CEO & President Conference Call Participants Toshiya Hari – Goldman Sachs C.J. Muse – Evercore ISI Vivek Arya –…

Image source: The Motley Fool. Nvidia (NVDA -0.49%)Q1 2024 Earnings CallMay 24, 2023, 4:45 p.m. ET Contents: Prepared Remarks Questions and Answers Call Participants Prepared Remarks: Operator Good afternoon. My name is David, and I’ll be your conference operator today. At this time, I’d like to welcome everyone to NVIDIA’s first-quarter earnings…

Elston KM, Leonard SP, Geng P, Bialik SB, Robinson E, Barrick JE. Engineering insects from the endosymbiont out. Trends Microbiol. 2022;30:79–96. Article  CAS  PubMed  Google Scholar  Brophy JAN, Triassi AJ, Adams BL, Renberg RL, Stratis-Cullum DN, Grossman AD, et al. Engineered integrative and conjugative elements for efficient and inducible DNA…

Genetic Counseling for Cancer Just like DNA, each person’s cancer is unique. The cause of cancer can be due to genetic mutations (changes in a gene). Most of these genetic changes happen after birth and are due to aging and environmental exposure among other factors. They are not hereditary and…

My colon cancer patients are getting younger. The diagnoses are happening just as some of these individuals are embarking on their plans for life, while others are in the crucial midst of parenthood. Given this, the tragedy of their cancers feels exponentially greater. This youthful trend in my clinic is…

Aase K, Jensen H, Muff S (2022) Genomic estimation of quantitative genetic parameters in wild admixed populations. Meth Ecol Evol 13:1014–1026 Article  Google Scholar  Aitken SN, Bemmels JB (2015) Time to get moving: Assisted gene flow of forest trees. Evol Appl 9:271–290 Article  PubMed  PubMed Central  Google Scholar  Alberto F…

Dubilier N, Bergin C, Lott C. Symbiotic diversity in marine animals: the art of harnessing chemosynthesis. Nat Rev Microbiol. 2008;6:725–40. Article  CAS  PubMed  Google Scholar  Sogin EM, Kleiner M, Borowski C, Gruber-Vodicka HR, Dubilier N. Life in the dark: phylogenetic and physiological diversity of chemosynthetic symbioses. Annu Rev Microbiol. 2021;75:695–718….

In this third episode of OncChats: Understanding Lynch Syndrome and Cancer Risk, Fay Kastrinos, MD, MPH, of Columbia University Herbert Irving Comprehensive Cancer Center, discusses testing guidance for identifying Lynch syndrome. Universal testing with MSI or immunohistochemistry [IHC] in all newly diagnosed colorectal cancer [CRC] is a firm guideline, and…

Researchers from the Bellwitz Biomedical Research Institute (IDIBEL), the Catalan Institute of Oncology (ICO), the Girona Biomedical Research Institute (IDIBGI), the Bellwitz Hospital and the Joseph Trueta Hospital have developed a method that can detect small changes in the body in a study. is capable of. DNA sequence that may…

Anderson MJ (2001) A new method for non‐parametric multivariate analysis of variance. Austral Ecol 26(1):32–46 Google Scholar  Anderson MJ (2004) PERMDISP: a FORTRAN computer program for permutational analysis of multivariate dispersions (for any two-factor ANOVA design) using permutation tests. Department of Statistics, University of Auckland, New Zealand, 24. Aykanat T,…

After conducting a cost-benefit analysis of population genetic testing, study investigators are recommending that U.S. health policymakers adopt routine genetic testing of all adults ages 40 and under for three genetic conditions posing a high risk of life-threatening illness. The research, published Tuesday in the journal Annals of Internal Medicine,…

Review . 2023 Apr 24;14(4):160-170. doi: 10.5306/wjco.v14.i4.160. Affiliations Expand Affiliations 1 Department of Hematology, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas 35019, Spain. 2 Department of Anatomical Pathology, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas 35019, Spain. 3 Department of Hematology, Hospital Universitario de Gran Canaria…

James Lu, MD, PhD, has been interested in the intersection of clinical care and genomics since the early days of next-generation sequencing (NGS) and the dawn of personal genomics in the mid-to-late 2000s. “In the early days of NGS, a lot of the early problems in that space, before Illumina…

Among individuals who consented to whole-exome sequencing (WES) and were identified as carriers of predisposition genes for hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (also known as hereditary nonpolyposis colorectal cancer or HNPCC), 39.2% would not have qualified for genetic screening under current guidelines. This conclusion is based…

N. Jewel Samadder, MD, MSc, FACG, AGAF The field of oncology is heading toward widespread genetic testing and implementation of screening methods with multi-cancer early detection, explained N. Jewel Samadder, MD, MSc, FACG, AGAF, adding that increased access and prospective research are key to both endeavors. “Eventually every patient will…

A research initiative co-led by Nobel laureate and CRISPR pioneer Jennifer Doudna, PhD, has been awarded $70 million to address health and climate challenges by combining the genome editing technology with genome-resolved metagenomics through the microbiome. TED’s Audacious Project, a collaborative funding effort designed to help solve grand-scale social impact…

Following current genetic screening guidelines may cause clinicians to miss as many as 40% of patients with high-risk hereditary cancer syndromes, according to research presented at the AACR Annual Meeting 2023. Researchers used whole-exome sequencing to identify patients with Lynch syndrome or hereditary breast and ovarian cancer syndrome (HBOC) in…

By The ASCO Post StaffPosted: 4/19/2023 12:31:00 PM Last Updated: 4/19/2023 3:45:30 PM Researchers revealed that 39.2% of patients who consented to whole-exome sequencing and were identified as carriers of predisposition genes for hereditary breast and ovarian cancer or Lynch syndrome did not qualify for genetic screening under current guidelines,…

Image Credit: © MicroOne [stock.adobe.com] Whole exome sequencing has been deemed a potential method to help execute CDCT1 genetic condition screening on large populations, according to study findings presented during the American Association for Cancer Research (AACR) Annual Meeting 2023. The findings, which were presented by Niloy (Jewel) Samadder, MD,…

Niloy (Jewel) Samadder, MD Whole exome sequencing testing identified genetic conditions in individuals who ordinarily would not have met current National Comprehensive Cancer Network (NCCN) guidelines for testing, according to data presented during the 2023 AACR Annual Meeting. The findings, which were presented by Niloy (Jewel) Samadder, MD, demonstrated that…

Allis, C. D. et al. Epigenetics 2nd edn (Cold Spring Harbor Laboratory Press, 2015). Law, J. A. & Jacobsen, S. E. Establishing, maintaining and modifying DNA methylation patterns in plants and animals. Nat. Rev. Genet. 11, 204–220 (2010). CAS  PubMed  PubMed Central  Google Scholar  Feng, S. et al. Conservation and…

Lisa Ximena Rodriguez-Rojas,1,2 Estephania Candelo,3,4 Harry Pachajoa,1,2,4 Juan Esteban Garcia-Robledo,3 Jose Antonio Nastasi-Catanese,1,2 Jorge Andres Olave-Rodriguez,2 Angela R Zambrano5 1Department of Human Genetics, Fundación Valle del Lili, Cali, Colombia; 2Faculty of Health Sciences, Universidad Icesi, Cali, Colombia; 3Fundación Valle del Lili, Centro de Investigaciones Clínicas, Cali, Colombia; 4Centro de Investigaciones…

Keum, N. & Giovannucci, E. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nat. Rev. Gastroenterol. Hepatol. 16, 713–732 (2019). Article  PubMed  Google Scholar  Sung, H. et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA…

The Audacious Project, an initiative housed at TED, encourages the world’s greatest changemakers to dream bigger. A new initiative led by Jennifer Doudna and Jill Banfield at the Innovative Genomics Institute and announced today at the TED Conference in Vancouver is a big dream that uses the smallest tools: microbes. The research initiative, “Engineering…

Daims H, Lebedeva EV, Pjevac P, Han P, Herbold C, Albertsen M, et al. Complete nitrification by Nitrospira bacteria. Nature 2015;528:504. Article  CAS  PubMed  PubMed Central  Google Scholar  van Kessel MA, Speth DR, Albertsen M, Nielsen PH, den Camp HJO, Kartal B, et al. Complete nitrification by a single microorganism….

Jayaraman, V., Toledo-Patino, S., Noda-Garcia, L. & Laurino, P. Mechanisms of protein evolution. Protein Sci. 31, e4362 (2022). Article  CAS  PubMed  Google Scholar  Huang, R. et al. Enzyme functional evolution through improved catalysis of ancestrally nonpreferred substrates. Proc. Natl Acad. Sci. USA 109, 2966–2971 (2012). Article  CAS  PubMed  PubMed Central …

Suttle, C. A. Environmental microbiology: Viral diversity on the global stage. Nat. Microbiol. 1, 16205 (2016). Article  CAS  PubMed  Google Scholar  Schulz, F. et al. Giant virus diversity and host interactions through global metagenomics. Nature 578, 432–436 (2020). Article  ADS  CAS  PubMed  PubMed Central  Google Scholar  Dutilh, B. E., Reyes,…

A new study indicates that skin neoplasms commonly occur in people with Lynch syndrome (LS), and may warrant dermatologic surveillance in this population. Study results were published in the Journal of the American Academy of Dermatology. “We found that 21% of individuals in our cohort had a history of skin…

Kirchberger PC, Schmidt ML, Ochman H. The ingenuity of bacterial genomes. Annu Rev Microbiol. 2020;74:815–34. Article  CAS  PubMed  Google Scholar  Rodríguez-Gijón A, Nuy JK, Mehrshad M, Buck M, Schulz F, Woyke T, et al. A genomic perspective across Earth’s microbiomes reveals that genome size in Archaea and Bacteria is linked…

Both GEDmatch’s and FamilyTreeDNA’s terms of service outline their policies for law enforcement use. But for many users, solving crimes is not their main motivator for signing up for these sites. Plus, not everyone reads the terms of service, and companies can not only change them at any time but may…

Breitbart M, Bonnain C, Malki K, Sawaya NA. Phage puppet masters of the marine microbial realm. Nat Microbiol. 2018;3:754–66. Article  CAS  PubMed  Google Scholar  Suttle CA. Marine viruses—major players in the global ecosystem. Nat Rev Microbiol. 2007;5:801–12. Article  CAS  PubMed  Google Scholar  Breitbart M. Marine viruses: truth or dare. Ann…

Yarmolinsky, D. A., Zuker, C. S. & Ryba, N. J. Common sense about taste: from mammals to insects. Cell 139, 234–244 (2009). Article  CAS  PubMed  PubMed Central  Google Scholar  Liman, E. R., Zhang, Y. V. & Montell, C. Peripheral coding of taste. Neuron 81, 984–1000 (2014). Article  CAS  PubMed  PubMed…

In a recent perspective article published in the journal Science, researchers at the Young-Onset Colorectal Cancer Center of Dana-Farber Cancer Institute emphasized that a better understanding of the etiology of early-onset colorectal cancer (EOCRC) is crucial to managing its increasing incidence worldwide. So, they identified five critical areas for investigating…

Brown JS O’Carrigan B Jackson SP Yap TA Targeting DNA Repair in Cancer: Beyond PARP Inhibitors. Cancer Discov. 2017; 7: 20-37 Farmer H McCabe N Lord CJ Tutt AN Johnson DA Richardson TB Santarosa M Dillon KJ Hickson I Knights C Martin NM Jackson SP Smith GC Ashworth A Targeting…

The following are today’s upgrades for Validea’s Price/Sales Investor model based on the published strategy of Kenneth Fisher. This value strategy rewards stocks with low P/S ratios, long-term profit growth, strong free cash flow and consistent profit margins. HARMONY GOLD MINING CO. (ADR) (HMY) is a small-cap value stock in…

Backgrounds Secondary to war wounds, surgery, trauma, etc., wound healing depends on the continuous proliferation of fibroblasts and collagen synthesis in the dermis.1,2 Skin scarring is considered as a natural outcome of the wound repair process. The incidence of scars after skin burns, trauma, and operations can be as high…

Amann, R. I., Ludwig, W., Schleifer, K. H. 1995. Phylogenetic identification and in situ detection of individual microbial cells without cultivation. Microbiol. Rev. 59:143–169. CrossRef  CAS  PubMed  PubMed Central  Google Scholar  Bench, S. R., Hanson, T. E., Williamson, K. E., Ghosh, D., Radosovich, M., Wang, K., Wommack, K. E. 2007….

Investors are often guided by the idea of discovering ‘the next big thing’, even if that means buying ‘story stocks’ without any revenue, let alone profit. But as Peter Lynch said in One Up On Wall Street, ‘Long shots almost never pay off.’ Loss-making companies are always racing against time…

The following are today’s upgrades for Validea’s Price/Sales Investor model based on the published strategy of Kenneth Fisher. This value strategy rewards stocks with low P/S ratios, long-term profit growth, strong free cash flow and consistent profit margins. CAREDX INC (CDNA) is a small-cap value stock in the Healthcare Facilities…

1. Introduction Soil harbors high abundance and diversity of prokaryotic microorganisms, with 1 g of soil containing up to 10 billion microbial cells (Torsvik and Øvreås, 2002) and 103–106 phylotypes (Bickel and Or, 2020), including many microorganisms that play critical biogeochemical roles (Crowther et al., 2019). With continuous expansion of prokaryotic…

Development & Operations Systems Administrator, The VEuPathDB Bioinformatics Resource Center University Overview The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World…

Introduction According to the National Library of Medicine, breast implant-associated in anaplastic lymphoma kinase negative large cell lymphoma is related to increased risks of BIA-ALCL.[1] Data On average, somewhere between 200,000 and 290,000 women in the United States have breast augmentation surgery annually. Some manufacturers of textured implant companies like…

Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, Boldrick JC, Sabet H, Tran T, Yu X, Powell JI, Yang L, Marti GE, Moore T, Hudson J, Lu L, Lewis DB, Tibshirani R, Sherlock G, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Warnke R, Levy R,…

Fastest DNA sequencing technique | Guinness World Records. www.guinnessworldrecords.com/world-records/675050-fastest%C2%A0dna-sequencing%C2%A0technique. Accessed 30 May 2022 Gorzynski JE, Goenka SD, Shafin K et al (2022) Ultra-rapid nanopore whole genome genetic diagnosis of dilated cardiomyopathy in an adolescent with cardiogenic shock. Circ Genom Precis Med CIRCGEN121003591. doi.org/10.1161/circgen.121.003591 First DNA Sequencing in Space a Game…

Below is Validea’s daily guru fundamental report for CRISPR THERAPEUTICS AG (CRSP). Of the twelve guru strategies we follow, CRSP rates highest using our Price/Sales Investor model based on the published strategy of Kenneth Fisher. This value strategy rewards stocks with low P/S ratios, long-term profit growth, strong free cash…

World Cancer Day offers a platform to raise the awareness of the latest advancements in oncology that are changing both the treatment of patients and the practice of clinicians around the world. In this regard, Next Generation Sequencing (NGS) continues to be at the forefront of precision medicine in oncology….

Luo, M. C. et al. Synteny analysis in rosids with a walnut physical map reveals slow genome evolution in long-lived woody perennials. BMC Genom. 16, 707 (2015). Article  Google Scholar  Martinez-Garcia, P. J. et al. The walnut (Juglans regia) genome sequence reveals diversity in genes coding for the biosynthesis of…

Image source: The Motley Fool. Alphabet (GOOGL -2.75%)Q4 2022 Earnings CallFeb 02, 2023, 4:30 p.m. ET Contents: Prepared Remarks Questions and Answers Call Participants Prepared Remarks: Operator Welcome, everyone. Thank you for standing by for the Alphabet fourth quarter 2022 earnings conference call. At this time, all participants are in a listen-only…

DOI: 10.18129/B9.bioc.illuminaHumanv4.db     This package is for version 3.12 of Bioconductor; for the stable, up-to-date release version, see illuminaHumanv4.db. Illumina HumanHT12v4 annotation data (chip illuminaHumanv4) Bioconductor version: 3.12 Illumina HumanHT12v4 annotation data (chip illuminaHumanv4) assembled using data from public repositories Author: Mark Dunning, Andy Lynch, Matthew Eldridge Maintainer: Mark…

European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK Claudia Calabrese, Nuno A. Fonseca, Lara Urban, Claudia Calabrese, Nuno A. Fonseca, Lara Urban, Liliana Greger, Nuno A. Fonseca, Lara Urban, Claudia Calabrese, Liliana Greger, Roland F. Schwarz, Oliver Stegle, Alvis Brazma, Alvis Brazma, Roland F. Schwarz & Oliver Stegle ETH Zurich, Zurich, Switzerland Natalie R. Davidson, André Kahles, Kjong-Van Lehmann, Natalie R. Davidson, André Kahles, Kjong-Van Lehmann, Stefan G. Stark, André Kahles, Kjong-Van Lehmann, Natalie R….

Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland Lauri A. Aaltonen Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK Federico Abascal, David J. Adams, Ludmil B. Alexandrov, Sam Behjati, Shriram G. Bhosle, David T. Bowen, Adam P. Butler, Peter J. Campbell, Peter Clapham, Helen Davies, Kevin J. Dawson, Stefan C. Dentro, Serge Serge, Erik Garrison, Mohammed Ghori, Dominik Glodzik, Jonathan Hinton, David…

The Broad Institute of MIT and Harvard, Cambridge, MA, USA Esther Rheinbay, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Julian M. Hess, Ziao Lin, Jaegil Kim, Yosef E. Maruvka, Pratiti Bandopadhayay, John Busanovich, Nicholas J. Haradhvala, Kiran Kumar, Gordon Saksena, Steven E. Schumacher, Chip Stewart, Manolis Kellis, Michael S. Lawrence, Pratiti Bandopadhayay, Rameen Beroukhim, Gad Getz, Nicholas J. Haradhvala, Julian M. Hess, Manolis Kellis, Jaegil Kim, Michael S. Lawrence, Ziao Lin, Yosef E. Maruvka, Esther Rheinbay, Gordon Saksena, Steven…

COPDGene Phase 3: Grant Support and Disclaimer: The project described was supported by Award Number U01 HL089897 and Award Number U01 HL089856 from the National Heart, Lung, and Blood Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National…

2020 Alzheimer’s disease facts and figures. Alzheimers Dement 2020. Mayeda ER, Glymour MM, Quesenberry CP, Whitmer RA. Inequalities in dementia incidence between six racial and ethnic groups over 14 years. Alzheimers Dement. 2016;12:216–24. Article  Google Scholar  Matthews KA, Xu W, Gaglioti AH, Holt JB, Croft JB, Mack D, et al….

TUESDAY, Nov. 22, 2022 (HealthDay News) — About 10 percent of patients with appendix cancer (AC) who undergo testing for hereditary cancer disposition harbor a gene sequence variation associated with cancer susceptibility, according to a study published online Nov. 11 in JAMA Oncology. Andreana N. Holowatyj, Ph.D., from the Vanderbilt…

Introduction Antimicrobials are the most important and useful therapeutic discovery in the history of medicine. It allows living beings to survive the microbial disease, enhances invasive surgical procedures, ensures animal health, and protects the food chain since 1928 after the discovery of penicillin. However, the indiscriminate use of antibiotics and…

Recent research analyzes mathematical models created to deduce conclusions about how evolution works at the level of populations of organisms. A study examines the benefits and drawbacks of evolutionary genomics. Claudius Ptolemy, an astronomer and mathematician from Alexandria in the second century, had a lofty goal. He wrote the Almagest, a…

Thank you. Yes, I downloaded the zip file and extracted into my files. When I share the address in the url bar it sends a link that cannot be opened by the reciever. With other files I can usually send the file to print and save in pdf format but…

Introduction Lung cancer is the major leading cause of tumour-related deaths throughout the world, while lung squamous cell carcinoma (LUSC) as the second most common histological type of lung cancer.1 Each year, almost 1.8 million people are diagnosed with lung cancer worldwide and 400,000 of these die from LUSC.2,3 Due to…

DOI: 10.18129/B9.bioc.illuminaRatv1.db     This package is for version 3.11 of Bioconductor; for the stable, up-to-date release version, see illuminaRatv1.db. Illumina Ratv1 annotation data (chip illuminaRatv1) Bioconductor version: 3.11 Illumina Ratv1 annotation data (chip illuminaRatv1) assembled using data from public repositories Author: Mark Dunning, Andy Lynch, Matthew Eldridge Maintainer: Mark…

Mah, C. L. & Blake, D. B. Global diversity and phylogeny of the asteroidea (Echinodermata). PLoS ONE 7, e35644. doi.org/10.1371/journal.pone.0035644 (2012). ADS  CAS  Article  PubMed  PubMed Central  Google Scholar  WoRMS. Asteroidea. Accessed at: www.marinespecies.org/aphia.php?p=taxdetails&id=123080. on 2021-08-02. Blake, D. B. Adaptive zones of the class Asteroidea (Echinodermata). Bull. Mar. Sci. 46,…

Rosen, E. D. & Spiegelman, B. M. What we talk about when we talk about fat. Cell 156, 20–44 (2014). CAS  PubMed  PubMed Central  Google Scholar  Kahn, S. E., Hull, R. L. & Utzschneider, K. M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444, 840–846 (2006)….

John Wikswo, founder and director of the Vanderbilt Institute for Integrative Biosystems Research and Education and Gordon A. Cain University Professor, is the principal investigator of a $1 million award from the National Science Foundation. The object is to build a pathbreaking “robot scientist”—a fully automated microfluidic system for parallel,…

Wu, W. et al. NDM metallo-β-lactamases and their bacterial producers in health care settings. Clin. Microbiol. Rev. 32, e00115–18 (2019). Yong, D. et al. Characterization of a new metallo-β-lactamase gene, bla NDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14…

The following are today’s upgrades for Validea’s Small-Cap Growth Investor model based on the published strategy of Motley Fool. This strategy looks for small cap growth stocks with solid fundamentals and strong price performance. EXLSERVICE HOLDINGS, INC. (EXLS) is a mid-cap growth stock in the Business Services industry. The rating…

doi: 10.3389/fmolb.2021.737821. eCollection 2021. Affiliations Expand Affiliations 1 Laboratory For Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow, Russia. 2 Moscow Institute of Physics and Technology, Dolgoprudny, Russia. 3 OmicsWay Corp., Walnut, CA, United States. 4 Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia. 5…

. 2021 Oct 2;219(2):iyab116. doi: 10.1093/genetics/iyab116. Affiliations Expand Affiliations 1 Department of Biology, Colorado State University, Fort Collins, CO 80523, USA and. 2 Department of Integrative Biology, University of Texas at Austin, Austin, TX 78712, USA. Item in Clipboard Gus Waneka et al. Genetics. 2021. Show details Display options Display options…

1. Hackstein JH, Stumm CK. Methane production in terrestrial arthropods. Proc Natl Acad Sci USA. 1994;91:5441–5. CAS  PubMed  PubMed Central  Article  Google Scholar  2. Hackstein JHP, van Alen TA. Fecal methanogens and vertebrate evolution. Evolution. 1996;50:559–72. PubMed  Article  PubMed Central  Google Scholar  3. Borrel G, McCann A, Deane J, Neto…

Introduction Today, malignant tumors (cancer) still severely imperil human health and cause millions of global mortality rates.1,2 Deep-seated solid tumors are challenging to cure by most therapeutic tools, mainly blamed on the complex tumor microenvironment (TME).3,4 Adoptive cell therapy (ACT), as one of the effective immunotherapeutic means for cancer treatment,…