Tag: MethylationEPIC

I want to identify the version of MethylationEPIC from the idat file.

I want to identify the version of MethylationEPIC from the idat file. 1 I have idat files of Infinium MethylationEPIC. I would like to know if the array of this file is Infinium MethylationEPIC v1.0 or Infinium MethylationEPIC v2.0. Is it possible to investigate the version of the MethylationEPIC from…

Continue Reading I want to identify the version of MethylationEPIC from the idat file.

Dementia with Lewy bodies post-mortem brains reveal differentially methylated CpG sites with biomarker potential

Weisman, D. & McKeith, I. Dementia with Lewy Bodies. Semin. Neurol. 27, 042–047 (2007). Article  Google Scholar  Foguem, C. & Manckoundia, P. Lewy Body Disease: Clinical and Pathological “Overlap Syndrome” Between Synucleinopathies (Parkinson Disease) and Tauopathies (Alzheimer Disease). Curr. Neurol. Neurosci. Rep. 2018 18:5 18, 1–9 (2018). CAS  Google Scholar …

Continue Reading Dementia with Lewy bodies post-mortem brains reveal differentially methylated CpG sites with biomarker potential

re-annotation of enhancers and long noncoding RNA genes and benchmarking of normalization methods

Illumina Infinium DNA Methylation (5mC) arrays are a popular technology for low-cost, high-throughput, genome-scale measurement of 5mC distribution, especially in cancer and other complex diseases. After the success of its HumanMethylation450 array (450k), Illumina released the MethylationEPIC array (850k) featuring increased coverage of enhancers. Despite the widespread use of 850k,…

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Batch-effect detection, correction and characterisation in Illumina HumanMethylation450 and MethylationEPIC BeadChip array data | Clinical Epigenetics

Experimental design and processing steps For the EpiSCOPE study [20], DHA supplementation and gender were balanced as much as possible across the 12 450K BeadChips on each glass slide, with these factors also randomly distributed over the 6 rows and 2 columns of 31 slides (Additional file 1: Fig. S1). Blood…

Continue Reading Batch-effect detection, correction and characterisation in Illumina HumanMethylation450 and MethylationEPIC BeadChip array data | Clinical Epigenetics

From idat Illumina Infinium MethylationEPIC to CNV analysis for homo/hetero-zigous deletion

From idat Illumina Infinium MethylationEPIC to CNV analysis for homo/hetero-zigous deletion 0 Hi, My group works on cancer and we have difficulty on a little part of our last project about malignant pleuric mesothelioma. I’m looking for help in the analysis of .idat from genome-wide DNA methylation profiles obtained via…

Continue Reading From idat Illumina Infinium MethylationEPIC to CNV analysis for homo/hetero-zigous deletion