Tag: multi-omic

Activated FGFR2 signalling as a biomarker for selection of intrahepatic cholangiocarcinoma patients candidate to FGFR targeted therapies

FGFR inhibitors have been developed to inhibit FGFR activation and signal transduction; notwithstanding, currently the selection of intrahepatic cholangiocarcinoma (iCCA) patients for these drugs only relies on the detection of FGFR2 genetic alterations (GAs) in tumor tissues or circulating tumor DNAs, without concomitant assessment of FGFR2 signalling status. Accordingly, we…

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what will therapy look like in 2034?

Drugs like PARP inhibitors and chimeric antigen receptor (CAR) therapies, and advancements in artificial intelligence in drug discovery, have spurred hope for improved cancer care in the past year. Rigorous research has paved the way for a declining cancer death rate – by 33% to be precise – since the…

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Post-Doctoral and PhD positions, La Sapienza University, Italy

Post-Doctoral and PhD positions: Join our vibrant team! We are currently hiring for various positions – Curators, Post-Docs, PhD, and Master Students. If you are passionate about Bioinformatics and Computational Biology, with a keen interest in Systems Biology, Network-Based, Multi-omic Integration, and deep learning, we want to hear from you!…

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Multiple Job openings at Gujarat Biotechnology Research Centre

Government of Gujarat has established Gujarat State Biotechnology Mission (GSBTM) as a nodal agency to develop overall development of biotechnology in the state in 2004. Major activities of GSBTM is promoting research and development in the field of biotechnology and supporting the development of biotechnology industries in the state. Besides…

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Senior Bioinformatics Scientist @ University of Chicago

Department BSD DFI – Translational Informatics About the Department The Duchossois Family Institute focuses on the role of commensal bacteria in enhancing disease resistance and is using genomic and metabolomic platforms to characterize the microbiome and its metabolites. Computational and bioinformatic expertise is required to understand how commensal bacteria impact…

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Brace yourselves for these trends in clinical research in 2024

There’s an air of cautious optimism about 2024, after a difficult few years following the end of the pandemic when investment in pharma and biotech research dropped substantially. After this significant reset, there’s now hope that in 2024, in line with emerging trends, the funds will be there for the…

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Research Bioinformatician I – Meyer Lab job with Cedars-Sinai

Job Summary: The Meyer lab at Cedars-Sinai is seeking one research bioinformatician to work on projects related to proteome informatics, mass spectrometry, metabolomics, multi-omic data integration, single cell transcriptomics, single cell genomics, single cell proteomics, computational drug discovery and/or cheminformatics. We are open to hiring at multiple levels of education,…

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Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain

Mouse brain tissues All experimental procedures using live animals were approved by the Salk Institute Animal Care and Use Committee under protocol number 18-00006. Adult (P56) C57BL/6J male mice were purchased from the Jackson Laboratory at 7 weeks of age and maintained in the Salk animal barrier facility on 12-h dark–light…

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Research Associate in Bioinformatics and Precision Medicine at Imperial College London

Location: St Mary’s, Paddington and South Kensington Campus Job Summary Applications are invited for the post of Research Associate/Fellow in Bioinformatics and Precision Medicine within the Department of Infectious Disease, Faculty of Medicine. You will lead analysis -omic datasets generated from clinical studies of acute infection to inform disease diagnosis…

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Postdoctoral Research Fellow, Computational Biology / Bioinformatics @ Visterra

Summary Visterra is seeking a highly talented, self-motivated and innovative Postdoctoral Research Fellow to join our Technology Platform team. The fellow will lead the conceptualization and implementation of advanced machine learning approaches to large single cell, spatial and multi-omic datasets. The role will involve developing creative approaches to leverage machine…

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PacBio Announces the Retirement of David Botstein, Ph.D., from its Board of Directors

MENLO PARK, Calif., Dec. 11, 2023 /PRNewswire/ — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, announced today that David Botstein, Ph.D., a member of PacBio’s Board of Directors, has retired from his position effective December 7, 2023.   “I would like to thank David for…

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Postdoctoral Position in Genomics – Tcheandjieu Lab, US

Postdoctoral Position in Genomics: The Tcheandjieu Lab at the Gladstone Institutes/UCSF is inviting applications for a Postdoctoral position in Genomics. This role offers an exciting opportunity to work on diverse biobanks, utilizing genomic and multi-omic approaches to enhance our understanding of cardiovascular diseases. Located in the heart of Silicon Valley,…

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Sequencing Reagents Market To Reach USD 29.2 Billion By

Fort Collins, Colorado, Dec. 04, 2023 (GLOBE NEWSWIRE) — According to DataHorizzon Research, The Sequencing Reagents Market size was valued at USD 7.4 Billion in 2022 and is anticipated to be valued USD 29.2 Billion by 2032 at a CAGR of 14.8%. The growing importance of genome sequencing for various diseases is…

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Postdoctoral Fellowship in bioinformatics and genetic epidemiology – University of Copenhagen – job portal

Job Portal                                                                                         Postdoctoral Fellowship in bioinformatics and genetic epidemiology   A two-year postdoctoral fellowship is available at the Section for Computational and RNA Biology, Department of Biology, University of Copenhagen. The position will be available from April 1st, 2024 or thereafter. The specific projects involve analyzing…

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Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings

Avsec, Ž. et al. Effective gene expression prediction from sequence by integrating long-range interactions. Nat. Methods 18, 1196–1203 (2021). Article  CAS  PubMed  PubMed Central  Google Scholar  Avsec, Ž. et al. Base-resolution models of transcription-factor binding reveal soft motif syntax. Nat. Genet. 53, 354–366 (2021). Article  CAS  PubMed  PubMed Central  Google…

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An adaptative integrative tool for paired single-cell multi-omics data

LIBRA overview. Credit: Quantitative Biology (2023). DOI: 10.15302/J-QB-022-0318 Single-cell multi-omics technologies allow a profound system-level biology understanding of cells and tissues. However, an integrative and possibly systems-based analysis capturing the different modalities is challenging. In response, bioinformatics and machine learning methodologies are being developed for multi-omics single-cell analysis. It is…

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Digital Genome Market is Estimated to Witness High Growth Owing

The Digital Genome Market is estimated for 2023 for the forecast period 2023-2030, as highlighted in a new report published by Coherent Market Insights. Market Overview: The digital genome is a digital representation of an organism’s complete set of DNA. It involves converting DNA sequences into digital data that can…

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Job Application for Scientist I, Bioinformatics at Scribe Therapeutics

Scientist I, Bioinformatics Scribe Therapeutics is a molecular engineering company focused on creating best-in-class in vivo therapies that permanently treat the underlying cause of disease. Founded by CRISPR inventors and leading molecular engineers Benjamin Oakes, Brett Staahl, David Savage, and Jennifer Doudna, Scribe is overcoming the limitations of current genome…

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Singleron Biotechnologies announces two co-authored abstracts at the American Society of Hematology conference

Using single cell multi-omics analysis to predict treatment outcome, develop disease prognostics and track patient responses to CAR T therapies COLOGNE, Germany, Nov. 17, 2023 /PRNewswire/ — Singleron Biotechnologies, a company at the forefront of developing and commercializing innovative single cell multi-omic analysis solutions for precision medicine, has announced two…

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Bioinformatics Scientist, multi-omics of Immune-Mediated Inflammatory Diseases

We are looking for a highly motivated postdoctoral researcher to work in the multi-omic analysis of Immune-Medated Inflammatory Diseases (IMIDs). The successful applicant will work in IMIDomics, a rapidly growing company focused on bringing the power of precision medicine to IMID patients. A fundamental strategy at IMIDomics is to integrate…

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Bioinformatics Scientist job with BostonGene

Summary: We are looking for a highly motivated and capable Bioinformatics Scientist with experience and interest in translational cancer research and the development of novel transcriptomic and genomic assays. This position requires experience with scientific programming, relational data systems, algorithm development, and statistical modeling. Key Responsibilities: Act as a core…

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5 Best Genome Sequencing Companies

The Genomic And Multi-omic Revolution The first human genome decoding started in 1990 and was first achieved in 2003. It also cost a staggering $3B. Fast forward 20 years, and the cost of genome sequencing has fallen to $600/genome. Or a 5,000,000x reduction in cost! And it could fall to…

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The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives | Military Medical Research

Kim JE, Li B, Fei L, Horne R, Lee D, Loe AK, et al. Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development. Immunity. 2022;55(12):2300-17.e6. Article  CAS  PubMed  Google Scholar  Xiao W, Su J, Gao X, Yang H, Weng R, Ni W, et al….

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Unveiling the transcriptomic and epigenetic secrets across 11 tumors

In a recent study published in Nature, researchers created a pan-tumor transcriptomic and epigenetic atlas using single-nucleus chromatin accessibility information and matched ribonucleic acid (RNA)-sequencing data. Study: Epigenetic regulation during cancer transitions across 11 tumour types. Image Credit: ART-ur/Shutterstock.com The researchers studied the spatiotemporal dynamics of chromatin decondensation and transcriptional…

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Telesis Bio Announces Commercial Release of Cell-free Amplification Kit for Generation of Transfection-scale DNA -November 03, 2023 at 12:02 pm EDT

New Kit offers BioXp automation workflow from candidate sequence to amplified DNA in days SAN DIEGO, Nov. 03, 2023 (GLOBE NEWSWIRE) — Telesis Bio Inc. (NASDAQ: TBIO), a leader in automated multi-omic and synthetic biology solutions, today announced the commercial release of its BioXp® De novo Cloning and Amplification kit…

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At ASHG, Fabric Genomics Announces Software Deals with Oxford Nanopore, DNAnexus

It’s been a busy week for Fabric Genomics. During the annual meeting of the American Society for Human Genetics in Washington DC this week, the company announced deals with both Oxford Nanopore Technologies and DNAnexus that are aimed at supporting the use of genomic information in clinical contexts. Fabric’s collaboration…

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Postdoctoral Research Fellow, Computational Biology / Bioinformatics job with Visterra, Inc.

Summary Visterra is seeking a highly talented, self-motivated and innovative Postdoctoral Research Fellow to join our Technology Platform team. The fellow will lead the conceptualization and implementation of advanced machine learning approaches to large single cell, spatial and multi-omic datasets. The role will involve developing creative approaches to leverage machine…

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Pacific Biosciences of California, Inc. (NASDAQ:PACB) Q3 2023 Earnings Call Transcript

Pacific Biosciences of California, Inc. (NASDAQ:PACB) Q3 2023 Earnings Call Transcript October 30, 2023 Pacific Biosciences of California, Inc. beats earnings expectations. Reported EPS is $-0.26, expectations were $-0.3. Operator: Good afternoon, everyone, and welcome to the PacBio Third Quarter 2023 Earnings Conference Call. All participants will be in a…

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Q3 2023 Pacific Biosciences of California Inc Earnings Call

Participants Christian O. Henry; President, CEO & Director; Pacific Biosciences of California, Inc. Susan G. Kim; CFO; Pacific Biosciences of California, Inc. Todd Friedman; Former Director of IR; Pacific Biosciences of California, Inc. Daniel Gregory Brennan; MD and Senior Tools & Diagnostics Analyst; TD Cowen, Research Division Eve Burstein Jack…

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Liquid Biopsy Provides Earlier Detection of an Inherited Cancer

Credit: AlexRaths/iStock Researchers at the Hospital for Sick Children (SickKids), the Ontario Institute for Cancer Research (OICR), and the University Health Network (UHN) have developed a liquid biopsy that an initial study has shown provides earlier detection cancer in individuals with Li-Fraumeni syndrome (LFS) than existing methods. LFS is hereditary…

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Diverse electron carriers drive syntrophic interactions in an enriched anaerobic acetate-oxidizing consortium

Nobu MK, Narihiro T, Mei R, Kamagata Y, Lee PKH, Lee P-H, et al. Catabolism and interactions of uncultured organisms shaped by eco-thermodynamics in methanogenic bioprocesses. Microbiome. 2020;8:111. Article  CAS  PubMed  PubMed Central  Google Scholar  Conrad R. Contribution of hydrogen to methane production and control of hydrogen concentrations in methanogenic…

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How can I devise a method like DESeq2 to give statistics for paired multiple -omic datasets?

Hi, I am a PhD student seeking advice on how I can devise a method like DESeq2 to give statistics for paired multiple -omic datasets that are aligned with those produced on RNA-Seq count data by DESeq2 (one of the multi-omic datasets for paired samples), so that they can be…

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Liquid Biopsy Detects Cancer Earlier in Patients with Inherited Disorder

Researchers at the Hospital for Sick Children (SickKids), the Ontario Institute for Cancer Research (OICR), and the University Health Network (UHN) have developed a method for analyzing blood samples that an initial study has shown can detect cancer in individuals with Li-Fraumeni syndrome (LFS) earlier than existing surveillance methods. LFS…

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Genomics for monitoring and understanding species responses to global climate change

Smith, T. B. & Bernatchez, L. Evolutionary change in human-altered environments. Mol. Ecol. 17, 1–8 (2008). Article  PubMed  Google Scholar  Bellard, C., Bertelsmeier, C., Leadley, P., Thuiller, W. & Courchamp, F. Impacts of climate change on the future of biodiversity. Ecol. Lett. 15, 365–377 (2012). Article  PubMed  PubMed Central  Google…

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Bioinformatics Scientist/Analyst/Postdoc – Job posted on PostdocJobs.com

OverviewFounded in 1946, the Oklahoma Medical Research Foundation (OMRF) is among the nation’s oldest, most respected independent, nonprofit biomedical research institutes. OMRF is dedicated to understanding and developing more effective treatments for human diseases, focusing on critical research areas such as Alzheimer’s disease, cancer, lupus, Multiple Sclerosis, and cardiovascular disease….

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Bioinformatics Analyst in Baltimore, MD for Johns Hopkins University

Details Posted: 14-Oct-23 Location: Baltimore, Maryland Salary: Open Categories: Research – Laboratory/Non-Laboratory Staff/Administrative Internal Number: 111298-en_US The Department of Neurology is seeking a Bioinformatics Analyst. The Analyst will be responsible for 2 major bioinformatics tasks requiring very specific bioinformatics and coding skills. Specific Duties & Responsibilities The collection, processing, and…

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Behold, the Human Brain Like Never Seen Before

12 Oct 2023 Understanding the human brain has entered a new era with the birth of a comprehensive cell atlas. Scientists used single-cell RNA sequencing, epigenetic analyses, and spatial mapping to study millions of brain cells from 100 brain regions, distinguishing 3,300 cell types. Researchers compared cell types to one…

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Senior Bioinformatics Software Engineer, Multi-omic data processing and integration job with Stanford University

Senior Bioinformatics Software Engineer, Multi-omic data processing and integration🔍School of Medicine, Stanford, California, United StatesNew📁Information Technology Services📅4 hours ago Post Date📅101019 Requisition # Stanford University is seeking a Software Developer 1 to join the Kundaje lab in the Department of Genetics to lead and assist with the development of data…

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Bioinformatics and Biostatistics Team Lead at The University of Manchester

About the role: This is a unique opportunity for an experienced and highly motivated data scientist, computational biologist or bioinformatician to lead an inventive, multidisciplinary Bioinformatic and Biostatistics Team (BBS). You will line manage 10-15 senior and junior bioinformaticians and will be making strategic decisions in a rapidly developing, multi-disciplinary…

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A Galaxy of informatics resources for MS-based proteomics

Introduction: Continuous advances in mass spectrometry (MS) technologies have enabled deeper and more reproducible proteome characterization, and a better understanding of biological systems when integrated with other ‘omics data. Bioinformatic resources meeting analysis requirements of increasingly complex MS-based proteomic data, and associated multi-omic data, are critically needed. These requirements included…

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Bioinformatics Analyst – Collabera

Job Title: Bioinformatic Analyst IILocation: RemoteDuration: 6 monthsPay Range: $38-$40/hour Job dscription:Bioinformatics/Computational Biologist (w/ focus on Genetics) Services Overview: This role involves support for the integration, organization, and analysis of large and complex multi-omics datasets, but not limited to transcriptomics, genetics, and epigenetics. A vital part of this role includes…

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Five impactful biotech companies to know in New York

New York – the place where people of all backgrounds come with hopes and dreams of making a better life for themselves – is just recently becoming a life sciences powerhouse, attracting many biotech companies, after a $1 billion public investment in the industry from the City of New York. …

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Is APAC Edging Closer to Clinical Application of Single-cell Tech?

Asia Pacific (APAC) is expected to be a major contributor to the growth of single cell technology as the market is driven by factors such as the growing demand for personalised medicine, advancements in sequencing technologies, and the increasing use of single cell analysis in drug discovery. While Japan is…

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Veracyte, Inc. hiring Senior/Principal Bioinformatics Scientist in United States

The Position The Discovery team and Data Analysis Team (DAT) at Veracyte are seeking an experienced bioinformatics scientist to drive next-generation sequencing (NGS) assay development and biomarker discovery in a vibrant group eager to explore and innovate where few have gone before.You will work at the intersection of the established…

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Into the Multi-ome: Four high-quality ‘omes from a single Revio SMRT Cell run

 As Marvel superheroes traverse the multiverse to save the day, genomics researchers are our superheroes as they navigate the daunting multiverse that is biology. The complex and dynamic interactions between the genome sequence, its epigenetic regulation, and their combined effects on transcript expression and splicing are fundamental to our understanding…

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Research Fellow, Human Genetics & Genomic Medicine job with UNIVERSITY OF SOUTHAMPTON

Human Genetics & Genomic Medicine Location:  Southampton General Hospital Salary:   £38,205 to £41,732 per annum Full Time Fixed Term until 01/11/2026 Closing Date:  Tuesday 24 October 2023 Interview Date:   To be confirmed Reference:  2458823AF Applications are invited for a Research Fellow position based at Southampton General Hospital. This…

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AI-Driven Approach Identifies Drug Targets for Neurodegenerative Disorders

Credit: Yuuji/Getty Images A collaboration between artificial intelligence (AI) biotech Insilico Medicine and the University of Cambridge has presented a new technique to identify drug targets for diseases where protein phase separation regulation is abnormal, such as Alzheimer’s and Parkinson’s disease and some cancers. Using a combination of Insilico’s AI-driven…

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Mission Bio Announces and Launches Single-Cell Measurable Residual Disease (MRD) Assay –

What You Should Know: Mission Bio, a leader in single-cell multi-omic solutions for precision medicine, announced the commercial launch of the Tapestri® Single-cell MRD (scMRD) AML Multiomics Assay. The company designed the scMRD AML Multiomics Assay to bring unprecedented resolution to disease relapse and recurrence in acute myeloid leukemia (AML), demonstrating the…

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Postdoctoral Fellow – EAZPOD 2023 at European Molecular Biology Laboratory (EMBL)

About the team/job EMBL-EBI and AstraZeneca are located nearby in Cambridge which will allow fellows to spend time at both sites and take advantage of the complementary expertise and opportunities this offers. Fellows will have easy access to scientific expertise, well-equipped computational facilities and an active seminar programme. Your role…

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Importance of Data Structures for Bioinformatics?

Importance of Data Structures for Bioinformatics? 0 Hello, I am currently an undergraduate student looking at going to Medical School. I am planning to take one or two gap years, where I want to apply for either an internship or research in bioinformatics / multi-omic analysis. Right now, I am…

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The Jackson Laboratory hiring Bioinformatics Analyst I – Carter Lab in Bar Harbor, Maine, United States

The Carter Lab focuses on computational and big data approaches to understanding Alzheimer’s disease. We are seeking a Bioinformatics Analyst to join our research in the genetics and genomics of dementias. This position will be part of our ongoing studies to understand the origins, progression, and potential treatments of Alzheimer’s…

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Dr. Serafim Batzoglou, Chief Data Officer at Seer – Interview Series

Serafim Batzoglou is Chief Data Officer at Seer. Prior to joining Seer, Serafim served as Chief Data Officer at Insitro, leading machine learning and data science in their approach to drug discovery. Prior to Insitro, he served as VP of Applied and Computational Biology at Illumina, leading research and technology…

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University of Michigan hiring Bioinformatics-Computational Biologist Lead/Senior 229148 in Ann Arbor, MI

How to ApplyA cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.SummaryThe Center for Statistical Genetics at…

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Senior Scientist, Oncology Bioinformatics at AstraZeneca in Luton, England R-168013

Do you have expertise in the analysis and interpretation of multi-omic data from complex immunopathologies? Would you like to apply your expertise to the development of new immuno-oncology therapies in a company that follows the science and turns ideas into life-changing medicines? Then AstraZeneca’s Early Oncology Data Science team might…

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Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes | BMC Medicine

Barker DJ. The origins of the developmental origins theory. J Intern Med. 2007;261:412–7. Article  CAS  PubMed  Google Scholar  Barker DJ, Gluckman PD, Godfrey KM, Harding JE, Owens JA, Robinson JS. Fetal nutrition and cardiovascular disease in adult life. Lancet. 1993;341:938–41. Article  CAS  PubMed  Google Scholar  Cain MA, Salemi JL, Tanner…

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The University of Manchester hiring Research Associate in Bioinformatics in Withington, England, United Kingdom

Applications are invited for the role of Post-Doctoral Research Associate in Bioinformatics to work in translational neuro-oncology in the Hamerlik lab in Manchester. The post involves dealing with multi-omic data analysis and storage, focusing particularly on data from spatial multi-omic profiling of brain metastases (incl. GeoMx platform, Mass Spectrometry Imaging)….

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University of Melbourne – Research Officer

Agency: Faculty of Medicine, Dentistry and Health Sciences Job no: 0055821 Work type: Fixed Term Location: Parkville Categories: Various categories Job no: 0055821 Location: ParkvilleRole type: Full-time; Fixed-term for 12 monthsFaculty: Medicine, Dentistry and Health SciencesDepartment/School: Department of Microbiology and Immunology, School of Biomedical SciencesSalary: Level A – $80,258 – $108,906 p.a. plus 17% super…

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Director, Bioinformatics – Richmond | Mendeley Careers

Title: Director, Bioinformatics Manager: VP, Bioinformatics Department: ResearchLocation: Richmond / Remote Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. Using its deep scientific expertise and…

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Transcriptome-wide association studies: recent advances in methods, applications and available databases

TWAS conducts association tests for each gene-trait pair leveraging analysis from eQTL effects and GWAS associations. Based on the idea of TWAS, the basic workflow can be divided into three steps, as illustrated in Fig. 1. It is noted that different models are contained in various stages and should be distinguished…

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Bioinformatics Analyst I/II job with Frederick National Laboratory for Cancer Research

Bioinformatics Analyst I/II Job ID: req3664Employee Type: exempt full-timeDivision: Bioinformatics and Computational ScienceFacility: NIHLocation: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc….

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Senior Bioinformatics Scientist Job – Karkidi

Key Skills Bioinformatics, Data Analysis, Data science techniques, Design, Effective communication skills, Genetics, Julia, Leadership Skill, Planning and organization, Python Programming, R Programming, Teamwork Job Description We are looking for a dynamic and proactive Bioinformatics Scientist with a demonstrated track record to join our fast-growing team at Inari Ghent. The…

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Frederick National Laboratory Bioinformatics Analyst II/III in Bethesda, MD | 862626552

Bioinformatics Analyst II/III Job ID: req3719Employee Type: exempt full-timeDivision: Bioinformatics and Computational ScienceFacility: NIHLocation: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc….

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Scientist Science jobs in Leonia

Broaden your search Refine your search Sign up for job alerts Get new jobs for this search by email Found 13 jobs We’re hiring an exceptionally talented PhD Nutrition Scientist to help us optimize and personalize healthy aging. Our ideal candidate will be pract… We’re hiring an exceptionally talented scientist…

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Spatial transcriptomics: recent developments and insights in respiratory research | Military Medical Research

Zepp JA, Morrisey EE. Cellular crosstalk in the development and regeneration of the respiratory system. Nat Rev Mol Cell Biol. 2019;20(9):551–66. Article  CAS  PubMed  PubMed Central  Google Scholar  Kiley JP. Advancing respiratory research. Chest. 2011;140(2):497–501. Article  PubMed  PubMed Central  Google Scholar  Goldstraw P, Ball D, Jett JR, Le Chevalier T,…

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Protein Drivers Connected to Multiple Cancer Types

Scientists from Washington University School of Medicine in St. Louis, the Broad Institute of MIT and Harvard, Brigham Young University, and other institutions have published several papers documenting their analysis of various driver proteins across multiple cancer types. The institutions are all part of the National Cancer Institute’s Clinical Proteomic…

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MD Anderson Research Highlights for August 16, 2023

Newswise — HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent…

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Scientists Uncover How Proteins Drive Cancer Growth

Scientists have completed an analysis of approximately 10,000 proteins involved in 10 different types of cancer, aiming to understand the proteins and their regulatory networks driving tumor growth beyond genetic information. This comprehensive proteomic study, which encompasses various chemical modifications, is shedding light on how cancer grows and spreads, offering…

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Telesis Bio Reports Second Quarter 2023 Financial Results

SAN DIEGO, Aug. 10, 2023 (GLOBE NEWSWIRE) — Telesis Bio Inc. (NASDAQ: TBIO), a leader in automated multi-omic and synthetic biology solutions, today reported financial results for the second quarter of 2023. “We achieved important milestones this quarter toward our path to profitability by delivering revenue growth again while expanding…

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Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism

Harley, R. M. et al. Labiatae. in Flowering Plants · Dicotyledons. The Families and Genera of Vascular Plants (ed. Kadereit, J. W.) vol. 7 167–275 (2004). Kokkini, S., Karousou, R. & Hanlidou, E. HERBS | Herbs of the Labiatae. Encyclopedia of Food Sciences and Nutrition 3082–3090 (2003) doi.org/10.1016/B0-12-227055-X/00593-9. Hao, D….

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Garvan Institute of Medical Research hiring Bioinformatics Research Assistant in Sydney, New South Wales, Australia

The Garvan Institute of Medical Research brings together world-leading clinicians and basic and translational researchers to break down barriers between traditional scientific disciplines and find solutions to disease. The Swarbrick lab are global leaders in the application of cellular genomics to human cancer, to find new diagnostics and treatments for…

Continue Reading Garvan Institute of Medical Research hiring Bioinformatics Research Assistant in Sydney, New South Wales, Australia

Frederick National Laboratory for Cancer Research hiring Bioinformatics Analyst II/III in Bethesda, Maryland, United States

Job ID: req3692Employee Type: exempt full-timeDivision: Bioinformatics and Computational ScienceFacility: NIHLocation: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USAThe Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some…

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Actalent hiring Remote Bioinformatics Analyst II in North Chicago, IL

DescriptionThis role involves support for the integration, organization, and analysis of multi-omics datasets, including but not limited to transcriptomics, genetics, and epigenetics. A vital part of this role includes ensuring the precision, quality, and comprehensiveness of our dataset repositories. The successful candidate will work in synergy with cross-functional and inter-organizational…

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Actalent hiring 100% Remote- Bioinformatics Analyst II in Chicago, Illinois, United States

Seeking Bioinformatics Analyst100% RemoteDescriptionTranscriptomics focusedThis role involves support for the integration, organization, and analysis of multi-omics datasets, including but not limited to transcriptomics, genetics, and epigenetics. A vital part of this role includes ensuring the precision, quality, and comprehensiveness of our dataset repositories. The successful candidate will work in synergy…

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Bioinformatics Engineer Job – Karkidi

Job Description About Betteromics  Betteromics is a Data Engineering Platform for Life Sciences.  We are a team of mission-driven professionals, with combined experiences from academia, science and technology companies. We believe that life science product development can be accelerated with industrial strength software platforms to generate, prepare, process and utilize…

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ctDNA and Lung Cancer | SpringerLink

Abbosh C, Birkbak NJ, Wilson GA, et al (2017) Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution. Nature 545:446–451. doi.org/10.1038/nature22364 CrossRef  CAS  PubMed  PubMed Central  Google Scholar  Adalsteinsson VA, Ha G, Freeman SS, et al (2017) Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. Nat Commun…

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Highlights from the 2023 Single-Cell and AI in Medicine Symposium

By Randall C. Willis with review and comments from Fabrice Chouraqui, Laurens Kruidenier, Chad Nusbaum, Diogo Camacho  August 2, 2023 | “Technology and computation are revolutionizing the way we are creating and developing new drugs,” Cellarity CEO Fabrice Chouraqui announced to open the Second Single-Cell and AI in Medicine Symposium…

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Bioinformatics Analyst (EQTL/GWAS/Fine Mapping/Colocalization) – Rangam Infotech Pvt Ltd

Schedule: 9AM-5PM CT or ET Bioinformatician/Computational Biologist – transcriptomics focused Linux & Unix exp needed. Experience in the analysis and integration of NGS data. Prior research experience in studying immunological diseases areas is a plus. Experience working in HPC or Linux platform. Transcriptomic or genetic data exp is a must…

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BioSpace hiring Bioinformatics Analyst I/II in Bethesda, Maryland, United States

Job ID: req3664Employee Type: exempt full-timeDivision: Bioinformatics and Computational ScienceFacility: NIHLocation: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USAThe Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some…

Continue Reading BioSpace hiring Bioinformatics Analyst I/II in Bethesda, Maryland, United States

Bioinformatics Analyst II – tellus solutions

Job Description:Services Overview: This role involves support for the integration, organization, and analysis of large and complex multi-omics datasets, including but not limited to transcriptomics, genetics, and epigenetics. A vital part of this role includes ensuring the precision, quality, and comprehensiveness of our dataset repositories. The successful candidate will work…

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Postdoctoral Researcher in Microbial Informatics, Oxford Univ, UK

Postdoctoral Researcher in Microbial Informatics: The Kennedy Institute of Rheumatology at the Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences is seeking a Postdoctoral Researcher with expertise in bioinformatics/computational biology and a keen interest in human genetics and the microbiome. As a member of the Oxford Centre for Microbiome Studies…

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Fore Genomics Adopts DNAnexus Platform to Access and Analyze Whole-Genome Newborn Screening Data

Comprehensive cloud platform provides industry-leading data quality, security, privacy, and compliance for ongoing service that screens for more than 300 inherited conditions with automated annual re-analysis MOUNTAIN VIEW, Calif. & LA JOLLA, Calif.–(BUSINESS WIRE)– DNAnexus, Inc., the leading provider of cloud-based genomic and biomedical data access and companion analysis software,…

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Bioinformatics Analyst II/III job with BioSpace, Inc.

Job Details Bioinformatics Analyst II/III Job ID: req3605 Employee Type: exempt full-time Division: Bioinformatics and Computational Science Facility: NIH Location: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and…

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Bioinformatics-Computational Biologist Lead/Senior job with University of Michigan

Bioinformatics-Computational Biologist Lead/Senior Apply Now How to Apply A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this…

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Senior Scientist, Translational Bioinformatics job with CSL – Australia

The Opportunity: We have an opportunity available for a Senior Scientist, Translational Bioinformatics to join our Research Data Science team. In this newly created position, you will provide scientific and technical expertise to help answer biomedical research questions at the pre-clinical and clinical stage of drug development using advanced bioinformatics….

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Research Fellow in Medical Epigenomics job with UNIVERSITY OF SOUTHAMPTON

Human Genetics & Genomic Medicine Location:  Southampton General Hospital Salary:   £34,980 Per annum Full Time Fixed Term until 31 May 2026 Closing Date:  Monday 14 August 2023 Interview Date:   To be confirmed Reference:  2379023AF We are looking to recruit a researcher with PhD or equivalent qualification in the…

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Postdoctoral Research Scientist – Columbia University – job portal

< We are seeking a highly motivated postdoctoral candidate with formal training in Bioinformatics, Statistical Genetics, Data Science, or Genetic Epidemiology. A postdoctoral position is immediately available to work on multiple NIH-funded projects on the Genetic Epidemiology of  Alzheimer’s Disease. Projects include: (1) a large scale Mexican-American cohort; (2) families…

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New York Genome Center hiring Postdoctoral Research Associate (Bioinformatics), MacMillan CSNCG in New York, New York, United States

The incumbent Postdoctoral Research Associate will support the “Copy number alterations and epigenetic rewiring in single cells that affect the activity and efficacy of genome-targeting drugs” project as part of the MacMillan Center for the Study of the Non-Coding Cancer Genome (CSNCG). The MacMillan CSNCG is a partnership between The…

Continue Reading New York Genome Center hiring Postdoctoral Research Associate (Bioinformatics), MacMillan CSNCG in New York, New York, United States

Genomic Comparison Between African American Men & European American Men with Prostate Cancer

Read the Full Video Transcript Charles Ryan: Hello, I’m delighted today to speak with Isra Elhussin, MBDS. Dr Elhussin is actually a PhD candidate at Tuskegee University in Tuskegee, Alabama and will soon be doing a postdoctoral at Johns Hopkins. She was recently named as a next gen star of the…

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Principal Bioinformatics Engineer Job Opening in Waltham, MA at BIO-TECHNE

Job Details Level:    Experienced Job Location:    Waltham MA – Waltham, MA Position Type:    Full Time Education Level:    Graduate Degree Salary Range:    Undisclosed Travel Percentage:    Up to 10% Job Shift:    Day Job Category:    Research Description Principal Bioinformatics Engineer   The Opportunity Exosome Diagnostics, a Bio-Techne brand (NASDAQ: TECH), is a global…

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Research Associate in Systems Biology/Bioinformatics at University of Sheffield

This is an outstanding opportunity for an ambitious academic to join the Department of Neuroscience at The University of Sheffield and make a significant contribution to Neuroscience research through the application of Systems Biology.  We are seeking a non-clinical academic to join the multidisciplinary teams of researchers who are investigating…

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AstraZeneca hiring Associate Director, Cell Therapy Bioinformatics in Gaithersburg, Maryland, United States

Do you have expertise in the analysis and interpretation of genomic data from cancer cell therapies? Would you like to apply your expertise to the development of new therapies in a company that follows the science and turns ideas into life-changing medicines? Then AstraZeneca’s Early Oncology Data Science team might…

Continue Reading AstraZeneca hiring Associate Director, Cell Therapy Bioinformatics in Gaithersburg, Maryland, United States

AI and Image Analysis Scientist

Zafrens, Inc., a biotechnology company that focuses on innovative product and drug development in the lifesciences industry, is seeking an AI and Image Analysis Scientist to join their team. The AI and Image Analysis Scientist will be responsible for developing and implementing algorithms for image analysis and processing of high-throughput…

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AI and Image Analysis Scientist – Bioinformatics and Drug Discovery – Zafrens, Inc.

Zafrens, Inc., a biotechnology company that focuses on innovative product and drug development in the lifesciences industry, is seeking an AI and Image Analysis Scientist to join their team. The AI and Image Analysis Scientist will be responsible for developing and implementing algorithms for image analysis and processing of high-throughput…

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Research Assistant Professor Cancer Prevention and Control job with GEORGETOWN UNIVERSITY

Research Assistant Professor Cancer Prevention and ControlGeorgetown University: Medical Center: School of Medicine: Oncology Location: Medical CenterOpen Date: Jun 28, 2023Deadline: Sep 01, 2023 at 11:59 PM Eastern Time DescriptionThe selected candidate will have completed all of the requirements for a doctorate in statistics, biostatistics, bioinformatics, or related field, by…

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Isolation and Transcriptome Analysis of Plant Cell Types

The feasibility and effectiveness of high-throughput scRNA-seq methods herald a single-cell era in plant research. Presented here is a robust and complete procedure for isolating specific Arabidopsis thaliana root cell types and subsequent transcriptome library construction and analysis. Transcriptome analysis on single cell or cell types can detect the subtle…

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Open access HoloFood Data Portal can help create more sustainable animal feeds

27 Jun 2023 — After scrutinizing the interplay between the diets of chicken and salmon and its effects on their complex microbiomes for four years, the HoloFood project, in partnership with the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), are launching the HoloFood Data Portal. The…

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3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer’s disease

Serrano-Pozo A, Frosch MP, Masliah E, Hyman BT. Neuropathological alterations in Alzheimer disease. Cold Spring Harb Perspect Med. 2011;1:a006189. Article  PubMed  PubMed Central  Google Scholar  Qiu C, Kivipelto M, von Strauss E. Epidemiology of Alzheimer’s disease: occurrence, determinants, and strategies toward intervention. Dialogues Clin Neurosci. 2009;11:111–28. Article  PubMed  PubMed Central …

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University of Michigan hiring Bioinformatics-Computational Biologist Senior 229150 in Ann Arbor, Michigan, United States

How to ApplyA cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.SummaryThe Center for Statistical Genetics at…

Continue Reading University of Michigan hiring Bioinformatics-Computational Biologist Senior 229150 in Ann Arbor, Michigan, United States

Frederick National Laboratory Bioinformatics Analyst II/III in Bethesda, MD | 848556171

Bioinformatics Analyst II/III Job ID: req3605Employee Type: exempt full-timeDivision: Bioinformatics and Computational ScienceFacility: NIHLocation: NIH Campus 9000 Rockville Pike, Bethesda, MD 20892 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc….

Continue Reading Frederick National Laboratory Bioinformatics Analyst II/III in Bethesda, MD | 848556171

Postdoc in single-cell cancer omics bioinformatics to Karolinska Institutet

Do you want to contribute to top quality medical research? Do you want to work in the exciting field of single-cell cancer genomics and contribute to improve our understanding of how tumors evolve to treat them more effectively? A postdoc position in single-cell cancer omics bioinformatics is immediately available in…

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