Tag: next-gen

NEW YORK – Pacific Biosciences said on Wednesday that it has made progress on the development of two sequencing platforms and announced that it is amending payment terms for its collaboration with Invitae on a high-throughput whole-genome sequencer. The Invitae collaboration is one of three R&D projects PacBio officials mentioned…

Human body like the Space is an endless frontier made even more complex by the irreversibility of life by the arrow of time. Similar to the mystery of origin of the Universe some problems in the human body are so complex, for example, the problem of qualia or the Hard…

    This package is for version 2.13 of Bioconductor; for the stable, up-to-date release version, see Rsubread. Rsubread: high-performance read alignment, quantification and mutation discovery Bioconductor version: 2.13 This R package provides easy-to-use tools for analyzing next-gen sequencing read data. Functions of these tools include quality assessment, read alignment,…

Blog Agriculture Biotechnology Though CRISPR-Cas enabled targeted genome engineering across a vast array of organisms, the system features major disadvantages. Frequent off-target mutagenesis, licensing restrictions and non-ideal economic license terms have inhibited commercial crop-science product upscaling, and, in many cases, entirely disqualified CRISPR’s use by many commercial crop developers. Seeking…

So my question comes in two parts: First of all is what I’m trying to do within reason given the tools I am using? I am investigating the shuffling effects of a recombinase on a known reporter sequence which subsequently generates libraries of unique sequences. By simulating all of the…

I’m a current undergraduate student whose just finishing up most of my fundamental courses in computer science and have some exposure to using computers to solve biologically-interesting problems and some of the big algorithms. I did a lot of my requirements pretty early, leaving me just upper-level courses (which according…

The Australian Federal Police has announced that they are using next-generation DNA sequencing technology to estimate the physical appearance of potential suspects. Based on DNA left at a crime scene, the technology – also known as massively parallel sequencing – can infer a person’s outwardly visible characteristics even in the…

Australian federal police have introduced they’re utilizing next-generation DNA sequencing know-how to predict the bodily look of potential suspects. Based on DNA left at a criminal offense scene, the know-how – also referred to as massively parallel sequencing – can predict externally seen traits of an individual even within the…

Australian federal police have announced they are using next-generation DNA sequencing technology to predict the physical appearance of potential suspects. Based on DNA left at a crime scene, the technology – also known as massively parallel sequencing – can predict externally visible characteristics of a person even in the absence…

A scientist uses a pipette to place a sample on a GridION in an Oxford Nanopore lab. Oxford Nanopore, the pioneer developer of DNA/RNA nanopore sensing tools that include its pocket-sized MinION DNA/RNA sequencer, has disclosed plans for an initial public offering that could value the company at a reported…

What You Should Know: – Cedars-Sinai Cancer and Tempus, a provider of artificial intelligence and precision medicine, are harnessing the power of big data and AI to design personalized cancer treatment options by creating virtual replicas of patients’ DNA, RNA, protein and other information to help identify the most effective…

Aurich Lawson | Getty Images In the US, September is National Prostate Cancer Awareness Month. This feature highlights why catching prostate cancer early can be critical, and what researchers are doing to improve the odds of controlling the disease once it’s found. Prostate cancer is a paradox. It has one…

The NextSeq 2000 is Illumina’s newest platform that uses advancements in optics, instrument design, and 2-channel chemistry to increase output. This new sequencing technology makes it possible for researchers to sequence a range of conventional and emerging applications by increasing throughput while cutting down on costs per run when compared…

Error in Robust Rank Aggregation 0 Hey guys, I was trying to merge my gene lists together using R, I had it as two datasets with 2 variables and when I created a list, Unfortunately when I’m aggregating. I am getting a error. Where am I going wrong and how…

With a handful of drugs for cystic fibrosis already approved, Vertex Pharmaceuticals has turned its attention to expanding its pipeline through collaborations and acquisitions the past few years. Today, the California company announced a new agreement with an old partner. Nearly three years ago, Vertex and Arbor Biotechnologies struck a deal….

VEP plugin uses 0 It is a small question, I downloaded all plugins and wrote in the input script to get plugin experimental functionalities (I am using merged cache Ref_Seq & Ensembl both). # make a file with a single variant using bash echo “17 43071077 43071077 T/C + variant_1″…

Tutorials for Robust Rank Agrregation 0 Hey guys, I Just want to know any tutorial showing Robust Rank Aggregation, The only tutorial I found is in Chinese, I am doing Robust Rank Aggregation for merging my gene lists. Thanks in Advance RNA-Seq R sequencing next-gen • 41 views Login before…

how to combine either Rna-seq datasets or results from analysis of Rna-seq datasets to get a visual result 0 Hey guys, I was doing a project based on Rna-seq analysis of a certain disease, I had taken various public datasets and had analyzed after which I had obtained a specific…

gender determination and chrX CN calls 1 I’m running CNVKit in amplicon mode on a set of tumor bam files generated with a small amplicon panel of 45 genes. The panel includes just one gene on chrX, and none on chrY. My reference is generated by 10 normal male samples…

CROP-seq data analysis 1 Hi, I am a new bie to single cell sequencing analysis. I have to analyze CROP-seq data, I am going through the following paper, www.nature.com/articles/nmeth.4177. I have to use cell ranger ( instead of DROP-seq software) as the first step to process single cell data.I wanted…