Tag: oocyte

Reproductive medicine is a field that constantly evolves, bringing new advancements and possibilities for individuals and couples seeking to start or expand their families. At the forefront of this transformative journey is Dr. Ian Hardy, an esteemed expert in reproductive endocrinology and a trailblazer in the realm of medical research….

Avise J (2008) Clonality: the genetics, ecology, and evolution of sexual abstinence in vertebrate animals. Oxford University Press, USA Book  Google Scholar  Avise JC (2015) Evolutionary perspectives on clonal reproduction in vertebrate animals. Proc Natl Acad Sci USA 112(29):8867–8873 Article  CAS  PubMed  PubMed Central  Google Scholar  Andrews S (2010) FastQC:…

Catalog number MNSI000A-1 Price Please ask Size 10 ug Shipping Temperature Blue Ice/ Dry Ice Product category Minicircle Technology Description Isotype or positive controls by peptides, antibodies and deactivated samples. Kit Plasmid mini made and maxi DNA purification kits can be silica gel or anion exchange, endotoxin free and are…

Lin, D. H. & Hoelz, A. The structure of the nuclear pore complex (an update). Annu. Rev. Biochem. 88, 725–783. doi.org/10.1146/annurev-biochem-062917-011901 (2019). Article  CAS  PubMed  PubMed Central  Google Scholar  Cabal, G. G. et al. SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope. Nature 441, 770–773 (2006)….

Xenopus transcription factor IIIA (TFIIIA) is phosphorylated on serine-16 by CK2. Replacements with alanine or glutamic acid were made at this position in order to address the question of whether phosphorylation possibly influences the function of this factor. Neither substitution has an effect on the DNA or RNA binding activity…

Transcribed image text: CHO (Chinese Hamster Ovary) cells were transfected with a plasmid containing TRPM8, and the response measured. This was not exactly the same as the TEVC oocyte experiments in the chali paper. but it still was a measure of ion movement the Hor fatio on the y-axis refers…

C A O’Brien and S L Wolin Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510. Abstract The Ro autoantigen is a 60-kD protein that is usually found in small cytoplasmic RNA-protein complexes known as Ro RNPs. Although the Ro RNPs are abundant and conserved components…

1. Introduction The ribosomal genes (rDNA) encoding 18S, 5.8S, 28S, and 5S ribosomal RNA (rRNA) are key elements of eukaryotic genomes, since their products are directly involved in the biogenesis and functioning of the ribosomes providing for protein synthesis. Multiple 45S rDNA clusters of the 18S, 5.8S, and 28S rRNA…

Rojansky R, Cha M-Y, Chan DC (2016) Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1. eLife 5:e17896. doi.org/10.7554/eLife.17896 CrossRef  CAS  PubMed  PubMed Central  Google Scholar  Wei W, Pagnamenta AT, Gleadall N et al (2020) Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA…

doi: 10.1093/nar/gkad209. Online ahead of print. Chongwei Bi  1 , Lin Wang  1 , Yong Fan  2 , Baolei Yuan  1 , Samhan Alsolami  1 , Yingzi Zhang  1 , Pu-Yao Zhang  3 , Yanyi Huang  4   5 , Yang Yu  3   6 , Juan Carlos Izpisua Belmonte  1   7 , Mo Li  1   8 Affiliations…

doi: 10.1093/nar/gkad208. Online ahead of print. Chongwei Bi  1 , Lin Wang  1 , Yong Fan  2 , Baolei Yuan  1 , Gerardo Ramos-Mandujano  1 , Yingzi Zhang  1 , Samhan Alsolami  1 , Xuan Zhou  1 , Jincheng Wang  3 , Yanjiao Shao  4 , Pradeep Reddy  4 , Pu-Yao Zhang  5 , Yanyi Huang  3   6 , Yang Yu  5…

The decline of oocyte quality has profound impacts on fertilization, implantation, embryonic development, and the genetic quality of future generations. One factor that is often ignored but is involved in the decline of oocyte quality is mitochondrial DNA (mtDNA) abnormalities. Abnormalities in mtDNA affect the energy production of mitochondria, the…

Adelaide Research & Scholarship Please use this identifier to cite or link to this item: hdl.handle.net/2440/137603 Citations Scopus Web of Science® Altmetric Type:  Journal article Title:  Mitochondrial DNA Deficiency and Supplementation in Sus scrofa Oocytes Influence Transcriptome Profiles in Oocytes and Blastocysts Author:  Okada, T.McIlfatrick, S.St. John, J.C. Citation:  International…

ATHENS, Greece, March 17, 2023 /PRNewswire/ — The results from the first clinical pilot study of maternal spindle transfer (MST) were published online in the journal, Fertility and Sterility, as an ahead of print version of the article. The project was carried out in Greece, at the Institute of Life-IASO IVF…

Review doi: 10.15252/embr.202255678. Online ahead of print. Affiliations Expand Affiliations 1 Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany. 2 Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy. Item in Clipboard Review Isabella Tolle et al. EMBO Rep….

“Golden mitochondria” by National Institutes of Health(NIH) is licensed under CC BY-NC 2.0. A controversial embryo engineering technique turns out not to work as planned. It is touted as a way to prevent the births of children with mitochondrial disease, and a few fertility clinics have been using it – without much evidence…

Entry 16333             CDS       T01002                                  Symbol Ins1, Ins-1, Ins2-rs1 Name (RefSeq) insulin I   KO K04526   insulin Organism mmu  Mus musculus (house mouse) Pathway mmu04010   MAPK signaling pathway mmu04014   Ras signaling pathway mmu04015   Rap1 signaling pathway mmu04022   cGMP-PKG signaling pathway mmu04066   HIF-1 signaling pathway mmu04068   FoxO signaling pathway mmu04072   Phospholipase D signaling pathway mmu04114   Oocyte…

1 Bomi8228 Probetacellulin Q9TTC5 2 Bomi5121 Dimethylaniline monooxygenase [N-oxide-forming] 3/Dimethylaniline oxidase 3/Hepatic flavin-containing monooxygenase 3/Trimethylamine monooxygenase Q8HYJ9 3 Bomi10437 Uterine milk protein P46201 4 Bomi9179 Signal transducer and activator of transcription 5A/Mammary gland factor Q95115 5 Bomi9003 Selenoprotein P P49907 6 Bomi3613 Acetyl-CoA carboxylase 1 Q9TTS3 7 Bomi5003 Cytoskeleton-associated protein…

Advanced paternal age results in low fertility, regardless of natural or assisted reproductive technology (Brandt et al., 2019, Kovac et al., 2013). Furthermore, the offspring of aged male subjects reportedly exhibit an increased risk of childhood cancer, psychological disease, and obstetrical complications (Brandt et al., 2019, Kovac et al., 2013)….

Vander, B. M. & Wyns, C. Fertility and infertility: Definition and epidemiology. Clin. Biochem. 62, (2018). Sun, H. et al. Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990–2017: Results from a global burden of disease study, 2017. Aging 11, 10952 (2019). Article …

Zhou, G. et al. Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray. Meat. Sci. 86(2), 440–450 (2010). CAS  PubMed  Article  Google Scholar  Alfaia, C. M. et al. Current feeding strategies to improve pork intramuscular fat content and its nutritional quality. Adv….

Background: Spinal Muscular Atrophy (SMA) is one of the most common autosomal recessive disorders in children after Duchenne muscular dystrophy affecting approximately 1 in 11,000 live births. There is no effective therapy for SMA; however, broadening our knowledge about the molecular genetics of the disease is resultant to develop potential…

Introduction Oocyte competence and quality depend on communication between the oocyte and the cumulus and theca cells. In the preantral phase, the members of the transforming growth factor β (TGF-β) superfamily are responsible for this communication and play an important role in folliculogenesis. Members of the TGF-β superfamily are related…

Mitochondria are the organelles that produce most of the chemical energy needed by the cell. Mitochondrial DNA (mtDNA) contains 16,569 nucleotides that can be mutated. Some of these mutations can lead to the development of mitochondrial diseases. While nuclear DNA (the well-known double helix, which encodes most of the genome)…

image: Immature mouse egg at a stage prior to ovulation, with mitochondria stained red view more  Credit: Marcos Roberto Chiaratti A research article published in the journal Science Advances describes a mechanism that helps explain how certain kinds of genetic disorders known as mitochondrial diseases are transmitted from mother to child. The study it reports…

PRIMARY care has for years been the cornerstone of the Australian health care system and GPs represent an integral part of it. As they are frequently responsible for the first, and sometimes only, contact of individuals with the health care system, they can profoundly affect a patient’s experience, expectations and…

The Yeast Metabolic Engineering group develops novel yeast cell factories to produce sustainable chemicals and natural products. We apply advanced genome editing, metabolic modeling, transporter engineering, and ‘omic data analyses for data-guided strain design. We are looking for two motivated, talented PhD students to join our team to study small…

doi: 10.1016/j.mex.2021.101419. eCollection 2021. Affiliations Expand Affiliations 1 Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA. 2 Cystic Fibrosis Research Center, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. Free PMC article Item in Clipboard Anil K Challa et al….