Tag: PacBio

Cho, C. et al. Haploinsufficiency of protamine-1 or-2 causes infertility in mice. Nat. Genet. 28, 82–86 (2001). Article  CAS  PubMed  Google Scholar  Oliva, R. Protamines and male infertility. Hum. Reprod. Update 12, 417–435 (2006). Article  CAS  PubMed  Google Scholar  Balhorn, R. The protamine family of sperm nuclear proteins. Genome Biol….

At PacBio, enabling the promise of genomics to better human health cuts right to the core of everything we do.That’s why in 2023 we created the STAR (Student Travel Awarded Researcher) Grant program. This exciting funding opportunity is intended to assist up-and-coming researchers in genomics-aligned fields with sequencing services and…

Isolate characteristics From June 2020 to October 2021, our analysis included a total of 28 isolates from patient and environmental samples, all subjected to Whole Genome Sequencing (WGS) (refer to Table 1). To ensure robustness and minimize the influence of sequencing errors on our findings, all 28 WGS datasets maintained a…

The Biostar Herald publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. You too can submit links here. This edition of the Herald was brought to you by contribution from Mensur Dlakic, Istvan Albert, and was edited…

Alston JM, Sambucci O. Grapes in the world economy. In: Cantu D, Walker MA, editors. The grape genome. Springer International Publishing; 2019. p. 1–24. Google Scholar  Rahemi A, Dodson Peterson JC, Lund KT. Grape rootstocks and related species. Cham: Springer International Publishing; 2022. Walker MA, Heinitz C, Riaz S, Uretsky…

Over the last 50 years, many monumental achievements in genetics and biology have unfolded before our eyes. From the invention of DNA sequencing technologies to the completion of the human genome project and the emergence of genomic medicine, we have made many intellectual and technological leaps in our understanding of…

Scheduled to open in early 2024, Azenta Life Sciences will be locating its GENEWIZ Multiomics and Synthesis Solutions site in Oxford, UK. Drawing upon the experienced team from the former Oxford Genomics Centre (OGC), the new Oxford Genomics Lab will provide fast and reliable genomics services from GENEWIZ to support…

%PDF-1.7 % 1 0 obj <>/Metadata 4 0 R/Pages 2 0 R/StructTreeRoot 3 0 R/Type/Catalog/ViewerPreferences 5 0 R>> endobj 4 0 obj <>stream Microsoft® Word 适用于 Microsoft 365 application/pdf Wang, Yusha Direct Pacbio sequencing methods and applications for different types of DNA sequences Microsoft® Word 适用于 Microsoft 365 2023-12-13T14:15:50+08:00 2023-12-14T18:37:50-08:00 2023-12-14T18:37:50-08:00…

Collection and handling of biospecimens obtained from participants in the randomized controlled clinical study of the efficacy of MDCF-2 The human study entitled ‘Community-based clinical trial with microbiota-directed complementary foods (MDCFs) made of locally available food ingredients for the management of children with primary moderate acute malnutrition (MAM)’ was approved…

Scheme of the study The overall pipeline of our study is presented in Fig. 1 and is described in detail in the methods section. We processed three types of samples: fresh water, sea sediment, and digestive system of a marine invertebrate M. gigas (“gut flora”). These samples were treated in triplicates…

The Center for Vaccine Development and Global Health (CVD) and the Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) seek applications for a faculty member with expertise in systems/computational biology and/or bioinformatics and demonstrated knowledge of the application of multiple omics-based approaches to immunology,…

RNA sequencing (RNA-seq) has become an indispensable tool for analyzing transcriptomes across all domains of life that can reveal insights about biology and disease. While the genome remains relatively constant for most species over brief time scales, the transcriptome –the sum total of expressed messenger RNA (mRNA) transcripts – varies…

MENLO PARK, Calif., Dec. 11, 2023 /PRNewswire/ — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, announced today that David Botstein, Ph.D., a member of PacBio’s Board of Directors, has retired from his position effective December 7, 2023.   “I would like to thank David for…

PacBio subreads.fastq files? 0 I have downloaded PacBio isoseq data as subreads.fastq format from NCBI. Most of the isoseq analysis tools require input as Pacbio .bam file, which is unavailable form NCBI. I want to perform differential gene expression analysis and alternative splicing analysis. I have confusion regarding the nature…

Seawater samples were collected from surface waters (SRF) and the bottom of the surface mixed layer (BML) in the Eastern Fram Strait region to investigate the distribution of carbohydrates and their utilisation by microbial communities. The ten sites were grouped into three categories based on the underlying seafloor topography (above-slope,…

The affine gap design space for selecting variant representations As demonstrated in Fig. 1, the main issue with a difference-based format such as VCF is that often there are multiple reasonable sets of variant calls that can be used to represent the same final sequence relative to a reference FASTA. Since…

Wang, P. et al. The genome evolution and domestication of tropical fruit mango. Genome Biol 21 (2020). Tang, C. et al. The rubber tree genome reveals new insights into rubber production and species adaptation. Nat Plants 2 (2016). Bredeson, J. V. et al. Sequencing wild and cultivated cassava and related…

mothur is an open source software package for bioinformatics data processing.[8] The package is frequently used in the analysis of DNA from uncultured microbes. mothur is capable of processing data generated from several DNA sequencing methods including 454 pyrosequencing, Illumina HiSeq and MiSeq, Sanger, PacBio, and IonTorrent.[9] The first release…

Hello everyone, and thank you for attending Lab Managers Automation Digital Summit. My name is Mary Beth DiDonna and I’ll be moderating this discussion. Welcome to this session, fully automated NGS sample preparation using a digital microfluidics platform. The Miro NGS Prep System is a compact digital microfluidics platform, which…

William T. Harvey1, Peter Ebert2,3,4, Jana Ebler2,4, Peter A. Audano5, Katherine M. Munson1, Kendra Hoekzema1, David Porubsky1, Christine R. Beck5,6, Tobias Marschall2,4, Kiran Garimella7 and Evan E. Eichler1,8 1Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195-5065, USA; 2Institute for Medical Biometry and Bioinformatics, Medical Faculty,…

PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse domains of biology.In this edition of our Powered by PacBio blog series, we highlight scientific papers from the month of…

Market Overview and Report Coverage DNA sequencing is the process of determining the exact order of nucleotides in a DNA molecule. It plays a crucial role in numerous areas such as genetic research, diagnosis of genetic disorders, personalized medicine, forensics, and agriculture. The process involves breaking down the DNA molecule,…

Introduction Rapidly advancing next generation sequencing technologies such as whole genome sequencing, genotyping-in-thousands by sequencing (GT-seq), and restriction-site-associated DNA sequencing (RAD-seq), are becoming more available and affordable for non-model organisms (Park & Kim, 2016; Ellegren, 2014; Van Wyngaarden et al., 2017; Bootsma et al., 2020). However, applying these technologies to…

Kinnex full-length RNA kit Kinnex single-cell RNA kit Kinnex 16S rRNA kit Kit advantage Full-length isoform discovery with flexible sample multiplexing Cell type-specific isoform isoform discovery with the highest accuracy Full-length 16S rRNA for species identification Total throughput 15M (Sequel II)40M (Revio) 30M (Sequel II)80M (Revio) 25M (Sequel II)60M (Revio)…

Statsndata has published a report on the process of collecting, analyzing and interpreting Next Generation DNA Sequencing (NGS) Market data. It has published reports on how companies collect, analyze and interpret their market data. This helps businesses better understand the Next Generation DNA Sequencing (NGS) Market, identify customer needs and…

See how ANU researchers are using thePippinHT for their DNA size selections High-molecular weight DNA extraction, clean-up and size selection for long-read sequencing | Sage Science Authors:  Ashley Jones, Cynthia Torkel, David Stanley, Jamila Nasim, Justin Borevitz, Benjamin Schwessinger The authors provide a protocol for preparing high molecular weight DNA sequencing libraries with a particular…

BGSC5E91BB7A0035EA0A mothur is an open source software package for bioinformatics data processing. The package is frequently used in the analysis of DNA from uncultured microbes. mothur is capable of processing data generated from several DNA sequencing methods including 454 pyrosequencing, Illumina HiSeq and MiSeq, Sanger, PacBio, and IonTorrent. The first…

How to estimate -g genome-size for Flye for de novo genome or for –meta mode when using Metaflye? 0 A few questions regarding the -g genome-size argument for Flye and MetaFlye: How much does this value influence the performance and output of the assemblies? How can I estimate the genome…

News:Course: Genome Assembly and Annotation 0 Dear all, We are excited to announce our upcoming online course on “Assembly and Annotation of Genomes,” scheduled for 18-22 March 2024. Course website: www.physalia-courses.org/courses-workshops/course20/ This comprehensive course is designed to introduce biologists and bioinformaticians to the principles of de novo genome assembly and…

November 29, 2023 | Greenphire and Florence Healthcare announce a technology partnership; Illumina and Veracyte join together in a multi-year agreement; Oxford Nanopore Technologies collaborates with Fabric Genomics and Saphetor to develop data technology for research; more.  Greenphire and Florence Healthcare announced a technology partnership that integrates two of the…

How to deeply sequence long inserts 1 I have a DNA library encoding scFv antibody genes that consist of VH gene (~380 bp) + linker peptide (54 bp) + VL gene (~380 bp), and the library contains about 1M unique antibodies. We’ve performed some iterative selections on the library such…

The PacBio RS II sequencer has been effectively utilized to generate a 1.27 Gb genome assembly of Dendrobium officinale [70]. By utilizing advanced sequencing technologies such as Illumina HiSeq, Nanopore, PacBio, and Hi-C, the results have revealed remarkable N50 values of 44 Mb and 65.35 Mb for Gardenia jasminoides and…

Vive la révolution! It’s not just desperate peasants who embrace radical change of the status quo. Innovations by technology companies are often hailed as revolutionary, disrupting the way we live and work. It’s worth remembering that many revolutionaries later became brutal dictators who ruled over their subjects with an iron…

In a world where innovation continues to shape our future, nanotechnology has emerged as a transformative force. India, with its remarkable scientific prowess and technological advancements, is at the forefront of this revolution. As we step into 2024, it’s an exciting time to explore the Top 5 Best Nanotech innovations…

Adenine, Guanine, Cytosine, and Thymine are the nucleotide base pairs that make up the majority of genetic information. DNA sequencing is essentially a way to determine the sequence of these base pairs. As per DelveInsight’s assessment, the DNA Sequencing Market is expected to grow at an immense pace in the…

Bengaluru-based MedGenome, a global partner for comprehensive multiomics solutions, has announced a grant for De Novo Genome Assembly and Annotation, in collaboration with American firm PacBio, a pioneer in long-read sequencing. The winner will be selected by a panel of experts from MedGenome and PacBio. The grant awardee will receive end-to-end…

Senior Bioinformatician Are you driven by the potential of gene therapy to transform lives and eager to be at the forefront of this revolutionary field? Look no further! Our dynamic start-up is seeking a talented and motivated Senior Bioinformatician to join our growing team of brilliant minds. [Please note: For application, please…

In the field of genetics, the concept of tandem repeats has been both scientifically fascinating, experimentally challenging, and motivating for technology development. As DNA sequencing technologies and analysis tools have evolved, scientists are now able to reveal the secrets hidden within these repetitive sequences, shedding light on their significance in…

Is there a good software to generate test genomics data? 0 For example if I input a reference genome FASTA can I get simulated FASTQ files for ONT sequencing or PacBio sequencing runs that could have produced that data? I’m trying to migrate over from Snakemake to Nextflow but from…

Título:  Autor:  Haro-Moreno, José M.; Cabello-Yeves, Pedro J.; Garcillán-Barcia, M. Pilar; Zakharenko, Alexandra; Zemskaya, Tamara I.; Rodriguez-Valera, Francisco Palabras clave:  Ca. PatescibacteriaLake BaikalLong-read metagenomics16S rRNA Fecha de publicación:  2023 Editor:  Springer Nature Citación:  Environmental Microbiome 18: 12 (2023) Resumen:  [Background]: Lake Baikal, the world’s deepest freshwater lake, contains important numbers…

Yourgene Health (part of the Novacyt group of companies), a leading international molecular diagnostics group, and PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced a collaboration to optimize size selection for long-read sequencing workflows. PacBio has qualified Yourgene’s LightBench® instrument for size selection of long DNA…

Yourgene Health and PacBio have announced a collaboration to optimise size selection for long-read sequencing workflows. PacBio has qualified Yourgene’s LightBench instrument for size selection of long DNA fragments, enabling high yields for HiFi sequencing data. Yourgene’s LightBench is an automated electrophoresis instrument, powered by Ranger Technology. This platform uses a patent-protected, machine-vision…

Ribosomal RNA 16S &18S 16S rRNA, and 18S rRNA Both belong to the ribosomal RNA category. Substances under the ribosomal RNA category convert genetic code into proteins. There’s two different subunits that are under the prokaryotic ribosome, one being a small subunit of 30S and the other being a large…

1. Introduction As a representative social insect with crucial ecological, economic and scientific value, the western honey bee (Apis mellifera) is widely reared and applied in the apicultural industry in considerable countries around the world [1]. In addition, A. mellifera has been applied as a research model for development, social…

Axial: linktr.ee/axialxyz Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio, Seranova Bio, Delix Therapeutics, Simcha Therapeutics, among others often when they are no more than an idea. We are fanatical about helping the rare inventor who is compelled to build…

De novo genome assemblies and genome annotation We assembled a de novo genome of a seven-year-old male SED from Ubon Ratchathani Zoo using a combination of Illumina short-reads (92.94 × coverage) and PacBio long-reads (61.6 × coverage) (GenBank accession number: JACCHN000000000). Additionally, we used MGI short-reads (52.15 × coverage) to assemble a de novo genome of…

As expected, the NGS companies were sharing their news, out in full force, at the annual American Society for Human Genetics (ASHG) meeting last week in Washington, DC. Whether the updates came from the expo booths showcasing instruments, or users sharing data in the lecture halls, each company had progress…

A new Arab pangenome reference has been constructed from 43 individuals enabling the study of variants and sequences of significance to the Arab population. In a newly released preprint entitled A draft Arab pangenome reference, researchers from UAE and several other countries developed both the nuclear and mitochondrial pangenome constructs…

The Genomic And Multi-omic Revolution The first human genome decoding started in 1990 and was first achieved in 2003. It also cost a staggering $3B. Fast forward 20 years, and the cost of genome sequencing has fallen to $600/genome. Or a 5,000,000x reduction in cost! And it could fall to…

PacBio HiFi sequencing technology continues to play an increasingly pivotal role in advancing critical research across the life sciences. In this blog series, we explore some of the latest and most exciting scientific papers and preprints that demonstrate the power of HiFi sequencing in unraveling new insights in areas as…

A new method called Chameleolyser, developed in Nijmegen, can find hidden genetic variations. This information is helping diagnose patients and might uncover new disease genes, as reported by Wouter Steyaert and Christian Gilissen from Radboud University in Nature Communications. Medical science has used exome sequencing for 15 years to study…

PacBio has announced it has begun taking orders for its new Kinnex RNA kits, which increase throughput for full-length RNA, single-cell RNA, and 16S rRNA sequencing on the firm’s long-read sequencing systems to enable large-scale studies at a resolution difficult to attain with short-read RNA sequencing. “The new family of…

Plink Error 1 Hi I am trying to convert ped file for hapmap3 I downloaded here ftp.ncbi.nlm.nih.gov/hapmap/genotypes/2009-01_phaseIII/plink_format/ and unzipped with binzip2 but I am getting the following error when running this command PLINK v1.90b5.2 64-bit (9 Jan 2018) www.cog-genomics.org/plink/1.9/ (C) 2005-2018 Shaun Purcell, Christopher Chang GNU General Public License v3…

History of Next-generation Sequencing Next Generation Sequencing (NGS) is a revolutionary genetic analysis technique that involves fragmenting the genetic material (DNA or RNA) and attaching oligonucleotides with known sequences through a process called adapter ligation. This allows the resulting fragments to interact with the selected sequencing platform. Subsequently, the bases within…

Consortium Aims to Share Best Practices and Increase our Understanding of Genetic Disease MENLO PARK, Calif., Nov. 2, 2023 /PRNewswire/ — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the creation of the HiFi Solves consortium. This global consortium brings together researchers from 15 leading…

Partnerships Maximize Value of HiFi Data and Complete the Full End-to-End Workflow for PacBio Customers. MENLO PARK, Calif., Nov. 1, 2023 /PRNewswire/ — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the addition of two tertiary analysis partners to PacBio Compatible. Geneyx and Golden Helix…

Starfish are some of the strangest creatures of the animal kingdom—so much so that scientists didn’t even know for sure if the animals had heads. A new study from the Stanford University and UC Berkeley discovered that—contrary to popular belief—starfish were actually giant walking heads, rather than headless sea creatures….

Microbiology forms the bedrock of modern genetics and biotechnology. Whether its basic science, alternative energy development, drug discovery, or human health – our planet’s smallest organisms play a critical role in the bigger picture. Even so, most microbial life remains unknown to science. And that’s why cutting-edge microbial ecology and…

For centuries, naturalists have puzzled over what might constitute the head of a sea star, commonly called a “starfish.” When looking at a worm, or a fish, it’s clear which end is the head and which is the tail. But with their five identical arms — any of which can…

Based on the MAS-Seq concatenation method, these three new assemblies can significantly increase throughput in RNAi applications. MENLO PARK, CA., October 31, 2023 /PRNewswire/ – PacBio (NASDAQ: PACB), a leading developer of high-quality, high-fidelity sequencing solutions, today announced that it has begun accepting orders for its innovative Kinnex RNA kits,…

Pacific Biosciences of California, Inc. (NASDAQ:PACB) Q3 2023 Earnings Call Transcript October 30, 2023 Pacific Biosciences of California, Inc. beats earnings expectations. Reported EPS is $-0.26, expectations were $-0.3. Operator: Good afternoon, everyone, and welcome to the PacBio Third Quarter 2023 Earnings Conference Call. All participants will be in a…

Participants Christian O. Henry; President, CEO & Director; Pacific Biosciences of California, Inc. Susan G. Kim; CFO; Pacific Biosciences of California, Inc. Todd Friedman; Former Director of IR; Pacific Biosciences of California, Inc. Daniel Gregory Brennan; MD and Senior Tools & Diagnostics Analyst; TD Cowen, Research Division Eve Burstein Jack…

Building on the MAS-Seq Concatenation Method, These Three New Kits can Significantly Increase Throughput in RNA Applications MENLO PARK, Calif., Oct. 31, 2023 /PRNewswire/ — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced it has begun taking orders for its groundbreaking Kinnex RNA kits, which…

In this tutorial we learn how to install sortmerna on Ubuntu 20.04. sortmerna is tool for filtering, mapping and OTU-picking NGS reads Introduction In this tutorial we learn how to install sortmerna on Ubuntu 20.04. What is sortmerna sortmerna is: SortMeRNA is a biological sequence analysis tool for filtering, mapping…

MENLO PARK, Calif., Oct. 30, 2023 /PRNewswire/ — PacBio (NASDAQ: PACB) today announced financial results for the quarter ended September 30, 2023. Third quarter results Revenue of $55.7 million, a 72% increase compared with $32.3 million in the prior-year period. Instrument revenue of $34.7 million compared with $11.4 million in the prior-year…

Zack TI, Schumacher SE, Carter SL, Cherniack AD, Saksena G, Tabak B, Lawrence MS, Zhang C-Z, Wala J, Mermel CH. Pan-cancer patterns of somatic copy number alteration. Nat Genet. 2013;45:1134–40. Article  CAS  PubMed  PubMed Central  Google Scholar  Dixon JR, Xu J, Dileep V, Zhan Y, Song F, Le VT, Yardımcı…

Antitrust laws are put in place to prevent unlawful activities like price fixing, as well as monopolies from forming, typically tied to big pharma. If these powerful companies were to swallow smaller biotechs in an attempt to fix prices, it would stifle competition, result in limited options for consumers, thereby…

The Center for Vaccine Development and Global Health (CVD) and the Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) seek applications for a faculty member with expertise in systems/computational biology and/or bioinformatics and demonstrated knowledge of the application of multiple omics-based approaches to immunology,…

The research study on Global DNA Sequence Analysis Software Market offers a detailed outline of the factors influencing the worldwide business scope. DNA Sequence Analysis Software Market research report shows the new market insights, current situation examination with upcoming trends, and breakdown of the products and services. The report provides…

Research by the Global Market Studies has reported a CAGR of 13.5% for the Global Epigenetics Market, expecting to surpass the USD 3 billion mark by 2028. LAS VEGAS, NEVADA, UNITED STATES, October 24, 2023 /EINPresswire.com/ — Research by the Global Market Studies has reported a CAGR of 13.5% for…

GIFS’ Omics and Precision Agriculture Laboratory (OPAL) is the first lab in Western Canada to offer genomics analyses services using PacBio’s new Revio DNA sequencer, the highest-capacity instrument the manufacturer has produced. The addition of Revio and other investments in high-throughput infrastructure and automation have significantly expanded OPAL’s scale and…

There is a need to profile microorganisms which exist pre-and-post-production of umqombothi, to understand its microbial diversity and the interactions which subsequently influence the final product. Thus, this study sought to determine the relative microbial abundance in umqombothi and predict the functional pathways of bacterial and fungal microbiota present. Full-length…

Neil Ward is the Vice President and General Manager for PacBio in EMEA. His role is to expand PacBio’s EMEA footprint, developing the team and its research partnerships to capitalise on the immense potential for genomics.  He spoke exclusively with Healthcare Digital to discuss the latest in rare disease diagnosis…

Kengo Kato Laboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases. Masanori Hashino Laboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases. Tamaki Ito Laboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases. Mari Matsui Department of Bacteriology II, National Institute…

Sample collection and bacterial isolation The strain DM-R-R2A-13T was obtained from a sample of Cannabis sativa in Andong, Republic of Korea. To isolate the strain, leaf samples (5.3 g) and root samples (6.3 g) were subjected to surface-sterilization using 1% sodium hypochlorite for 20 min followed by 70% ethanol for 10 s, and then…

Pacific Biosciences of California, Inc. PACB, popularly known as PacBio, recently announced the availability of a complete, standardized computational method for HiFi whole genome sequencing (WGS) data analysis, the PacBio WGS Variant Pipeline. The PacBio WGS Variant Pipeline will be available via GitHub. The single computational workflow is expected to…

The Quadram Institute (QI) is a pioneering interdisciplinary research centre at the forefront a new era in food and health research. It brings together clinical and non-clinical scientists in a new state-of-the-art building. Based on the Norwich Research Park, home of the John Innes Centre, The Norfolk and Norwich University…

Pacific Biosciences of California, Inc. (PACB Quick QuotePACB – Free Report) , popularly known as PacBio, recently announced the availability of a complete, standardized computational method for HiFi whole genome sequencing (WGS) data analysis, the PacBio WGS Variant Pipeline. The PacBio WGS Variant Pipeline will be available via GitHub. The…

Hope is not lost for the thousands of individuals dealing with rare or undiagnosed diseases, urged Neil Ward, Vice President and General Manager EMEA for PacBio talking at the Genomics England Research Summit. In his presentation to the event, Ward outlined the scale of the issue, saying that undiagnosed rare…

Nanopore Sequencing Market The global nanopore sequencing market report is a comprehensive report that provides a detailed analysis of the current status and future trends of the nanopore sequencing market worldwide. This report provides valuable information to industry stakeholders by offering an in-depth perspective on market dynamics, competitive landscape, growth…

Abstract: With the advancements in high-throughput sequencing technologies such as Illumina, PacBio, and 10X Genomics platforms, and gas/liquid chromatography-mass spectrometry, large volumes of biological data in multiple formats can now be obtained through multi-omics analysis. Bioinformatics is constantly evolving and seeking breakthroughs to solve multi-omics problems, however it is challenging…

MENLO PARK, Calif., Oct. 12, 2023 /PRNewswire/ — PacBio (NASDAQ: PACB) announced today that it will hold its quarterly conference call to discuss its third quarter 2023 financial results on Monday, October 30, 2023, at 4:30 pm Eastern Time. The call will be webcast and may be accessed at PacBio’s…

Paraphase Paraphase is a computational tool for variant calling in homologous genes, for either WGS or targeted sequencing. Paraphase was introduced for gene profiling of spinal muscular atrophy (SMA), for which it successfully identified full-length SMN1 and SMN2 haplotypes. This tool is also accessible through our partner platform DNAnexus. This…

  PacBio WGS Variant Pipeline Will Bring Standardization to PacBio HiFi Data Analysis MENLO PARK, Calif., Oct. 11, 2023 /PRNewswire/ — PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the availability of PacBio WGS Variant Pipeline – a complete, standardized…

PacBio announced the availability of PacBio WGS Variant Pipeline — a complete, standardized computational method for HiFi whole genome sequencing (WGS) data analysis. The new software pipeline will enable customers to resolve many different variant types, including single-nucleotide polymorphisms, insertions and deletions, structural variants, tandem repeats, segmental duplications, and copy…

The global target sequencing and resequencing market size is anticipated to reach around USD 45.72 billion by 2032 up from USD 5.74 billion in 2022 with a CAGR of 23.06% between 2023 and 2032. Targeted sequencing, often known as resequencing, is a technique for sequencing a sample’s partial genome or…

Prospects of Whole Genome Sequencing in Animal Breeding The development of high-throughput sequencing technologies has revolutionized animal genetics and genomics. The widespread use of whole-genome sequencing (WGS) allows detection of a full range of common and rare genetic variants of different types across almost the entire genome which facilitates rare…

The “Agrigenomics Market Trends and Insights” report is now offered in the store of Adroitmarketresearch.com. This comprehensive research report delves into the intricacies of the Agrigenomics Market, providing valuable insights into its current state, key players, market estimations, and future outlook. From analyzing the impact of COVID-19 to examining the…

Eman (Eman Khalaf) October 8, 2023, 4:50pm 1 Hi, I have many samples (~650) sequenced by PacBio platform. RStudio can not process dada function due to the memory limit of the software. The total size of the samples is 30 GB and I need to use pool=TRUE parameter. So, I…

Real metaHi-C datasets In this study, we leveraged several publicly available metagenomic Hi-C datasets, consisting of two short-read metaHi-C datasets and two long-read metaHi-C datasets. The specific sizes of raw datasets were shown in Supplementary Table 6. Two short-read metaHi-C datasets were generated from different microbial ecosystems, including human gut (BioProject:…

Pacific Biosciences of California, Inc. PACB, popularly known as PacBio, has been gaining from its slew of strategic deals over the past few months. The optimism led by a solid second-quarter 2023 performance and its product development activities are expected to contribute further. However, stiff competition and macroeconomic concerns persist….

Children’s Mercy Kansas City announced it is the first health care system to use 5-base HiFi sequencing, from PacBio, in the clinical setting to accelerate diagnoses for even more patients and families. The cutting-edge technology replaces rapid exome, chromosomal microarray analysis and other conventional diagnostic testing as a first line…

Errors running genome polishing with Arrow 0 Dear Biostars community, I am performing a genome polishing using Arrow, but I am getting errors immediately I launch the script. I have tried to use Arrow though gcpp version 2.0.2-2.0.2 (installed via bioconda), and using variantCaller version 2.3.3 Using gcpp, I got…

Introduction As an important zoonosis pathogen, Salmonella is widely distributed in nature and one of the four major pathogens causing global diarrhea diseases.1 Salmonella has six subspecies and 2659 serotypes, among which Salmonella Enteritidis (S. Enteritidis) are the most common serotypes causing Salmonella outbreaks.1 S. Enteritidis has a wide variety…

In a recent review published in Nature, a group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding ribonucleic acids (RNAs), and advocated for a universal annotation standard for clinical use. Study: The status of the human gene catalogue. Image Credit:…

DNA Extraction, Isolation, Purification Market Worth $6.10 Billion, Globally, by 2030 – Exclusive Report by The Insight Partners Pune, India, Oct. 04, 2023 (GLOBE NEWSWIRE) — The method through which the DNA is purified is DNA extraction, by using physical and/or chemical methods from proteins, cell membranes, and other cellular…

Hi all, I am trying to incorporate some complete/near complete 16s rRNA sequences that I have extracted from annotated genomes following some PacBio HiFi metagenomic sequencing I have done. The aim here is to compare these sequences against a V1-V2 16s rRNA sequencing dataset, generating a phylogenetic tree to see…

October 19, 2023 1:00 pm to 2:00 pm Event sponsored by: Contact: Franco, Matthew Speaker: Dr. Devi Lenz During the past two decades, a new generation of high-throughput DNA sequencers has transformed biomedical and biotechnology research. These new technologies have fostered the development of a wide range of applications to…

ABOUT THE ROLE Working within the Department of Applied Sciences, this role involves both teaching and research. The successful candidate will be part of a multidisciplinary team that teaches undergraduate and postgraduate forensic science students, on programmes accredited by the Chartered Society of Forensic Sciences. This post will involve designing,…

VALENCIA, Spain–(BUSINESS WIRE)– BioBam, the leading bioinformatics software company, is pleased to announce OmicsBox 3.1, its latest version packed with innovative features designed to empower researchers, scientists, and bioinformaticians in their pursuit of advanced omics data analysis and interpretation. This press release features multimedia. View the full release here: www.businesswire.com/news/home/20231003214238/en/…