Tag: phd

ADC Therapeutics Announces Updated LOTIS-2 Results

LAUSANNE, Switzerland, June 09, 2023 (GLOBE NEWSWIRE) — ADC Therapeutics SA (NYSE: ADCT) today announced updated results from LOTIS-2, the pivotal Phase 2 clinical trial of ZYNLONTA® (loncastuximab tesirine-lpyl) in patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL). The data are being presented in a poster today at the European…

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ADC Therapeutics (ADCT) Announces Updated LOTIS-2 Results Demonstrating Durable, Long-Term Responses of ZYNLONTA in R/R DLBCL

ADC Therapeutics SA (NYSE: ADCT) today announced updated results from LOTIS-2, the pivotal Phase 2 clinical trial of ZYNLONTA® (loncastuximab tesirine-lpyl) in patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL). The data are being presented in a poster today at the European Hematology Association 2023 Hybrid Congress (EHA2023) and will…

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Senior Teaching Associate (Bioinformatics) at University of Cambridge

The Bioinformatics Training Facility within the School of Biological Sciences is seeking to recruit a Senior Teaching Associate to lead the development and delivery of Bioinformatics focussed training materials at the University of Cambridge. The post holder will be based in the Bioinformatics Training Facility. Reporting to the Head of…

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Genmab Showcases Data From Comprehensive Epcoritamab

Media Release COPENHAGEN, Denmark; June 9, 2023, at 9:00am CEST Results from phase 1/2 EPCORE™ NHL-2 trial investigating epcoritamab in combination with rituximab-lenalidomide (R2) showed a 98 percent overall response rate (ORR), 87 percent complete metabolic response (CMR) in patients with relapsed or refractory (R/R) follicular lymphoma (FL) Results from…

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Genmab Showcases Data From Comprehensive Epcoritamab Development Program in Patients Across B-Cell Lymphomas at European Hematology Association (EHA) Annual Meeting 2023

COPENHAGEN, Denmark–(BUSINESS WIRE)– Genmab A/S (Nasdaq: GMAB) today announced data from its ongoing phase 1/2 EPCORE™ NHL-2 trial investigating epcoritamab, a T-cell engaging bispecific antibody administered subcutaneously, in combination with rituximab-lenalidomide (R2) showed an overall response rate (ORR) of 98 percent and complete metabolic response (CMR) of 87 percent in…

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Full Form, Courses, Top Colleges, Syllabus, Admission, Fees, Jobs 2023-24

MBA in Bioinformatics permits the scholars to analyze the utility of automatic know-how in accumulating and class of organic molecular genetics and genomes statistics for in addition processing and studies analysis. The applicants actively find out how useful the garage of this touchy statistics can cause undertaking of most important…

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Postdoctoral Associate- Brain Tumor Bioinformatics

Summary A postdoctoral position is immediately available in the Taylor laboratory to study, plan, direct and conduct specialized and advanced research experiments with Neuro oncology research program. This position will be responsible for evaluation and analyzing data. Job Duties Designs and performs experimental studies that directly answer the…

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Urgently Looking for Online Bioinformatics Training in Baner, Pune – Job ID 13616914

Some of the Bioinformatics Training Jobs are given below. Average Salary for Bioinformatics Training Jobs is ₹ 2,000 – ₹ 10,000 per month. You can further estimate salary using the Bioinformatics Fees calculator. S Online Bioinformatics Training Bioinformatics Teacher Job by Shubham K. Online, Online (video chat via skype, google…

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Golidocitinib Yields Durable Antitumor Responses in Relapsed/Refractory PTCL

Golidocitinib, an orally available, JAK1-selective inhibitor, demonstrated promising antitumor activity and durable responses in patients with relapsed or refractory (R/R) peripheral T-cell lymphoma (PTCL), according to research at the ASCO Annual Meeting 2023. The findings were from the primary analysis of efficacy and safety of the multinational, open-label, phase 1/2…

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Simple Test May Detect Breast, Ovarian Cancer Risk Without Genetic Sequencing

Researchers from Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and Medical University of Lodz have found a way to detect increased cancer risk associated with BRCA1 and BRCA2 mutations without genetic sequencing, according to a new study in Nature Communications. The assessment isn’t based on the presence of BRCA1/2 gene…

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Neoadjuvant Chemotherapy Is a Viable Option in Locally Advanced Colon Cancer

Neoadjuvant chemotherapy for locally advanced colon cancer did not improve survival but showed some favorable outcomes, phase 3 study results showed. For patients with locally advanced colon cancer, upfront surgery is standard of care. Adjuvant chemotherapy is added to reduce the risk for recurrence in patients with risk factors. However,…

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Wildfire Health Risks; An Rx for Love; Francis Collins’ Graduation Serenade

The following contains links to social media websites including Twitter, TikTok, Instagram, Facebook, and LinkedIn. As Canadian wildfire smoke spreads across the northeastern U.S. @rubin_allergy shares preventive measures to protect yourself. And a Yale PhD student explains compelling reasons why we should be concerned about the health impacts of wildfire…

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Accelerate PyTorch with DeepSpeed to train large language models with Intel Habana Gaudi-based DL1 EC2 instances

Training large language models (LLMs) with billions of parameters can be challenging. In addition to designing the model architecture, researchers need to set up state-of-the-art training techniques for distributed training like mixed precision support, gradient accumulation, and checkpointing. With large models, the training setup is even more challenging because the…

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Novogene Europe announces ISO 15189:2012 certification for clinical sequencing services.

Novogene Europe announces ISO 15189:2012 certification for clinical sequencing services. ISO 15189:2012 extends Novogene’s clinical offering to an end-to-end service including DNA extraction, library preparation, sequencing and bioinformatic analysis. Novogene, a leading provider of genomics services and solutions, has announced the ISO 15189:2012 certification of its Cambridge Sequencing Centre. This…

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Vizgen hiring Senior Bioinformatics Scientist in Cambridge, Massachusetts, United States

Vizgen, Inc. – Cambridge, MAVizgen is a rapidly growing company developing the next generation of spatially resolved genomic profiling tools that enable researchers to gain new insight into the biological systems that underlie human health and disease. The company’s groundbreaking MERFISH spatial transcriptomics technology images RNA molecules with high accuracy…

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CSIC Project Receives 1.9 Million Euros From The European Union To Develop More Sustainable And Safer Batteries

The work of researcher at the Institute of Materials Science of Barcelona (ICMAB-CSIC) Alexandre Ponroch has been recognized by the European Research Council (ERC) through a ‘Consolidator Grant’ 2022. Endowed with approximately 2 million Euros, this economic support will give researchers 5 years to develop the MultimetalBat project. The aim…

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[Full Time] Senior Bioinformatics Engineer at Ginkgo Bioworks (United States)

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms.    Ginkgo…

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Using Genomics To Unlock The Full Potential Of Industrial Hemp

Plant biologist Alex Harkess, PhD, and his lab at HudsonAlpha Institute for Biotechnology are on a mission to change the future of food and fiber crops, one flowering plant species at a time. Much of plant breeding and global food production relies on the pollination of flowers to produce fruits…

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Postdoctoral Associate- Bioinformatics/Cancer Genomics

Summary The Cheng Lab at Baylor College of Medicine is searching for highly motivated and talented post-doc candidates to work on Bioinformatics and Computational Biology in Cancer Genomics and Immunology. The position will be involved in the development and/or application of computational approaches to understand the mechanism of cancer…

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Postdoc in Bioinformatics: Structural variations associated to

Postdoc in Bioinformatics: Structural variations associated to circular DNA in cancer Department of BiologyFaculty of Science University of Copenhagen   Department of Biology, Faculty of Science at University of Copenhagen is offering a position in bioinformatics for a postdoc for the analysis of extrachromosomal circular DNA. Job description – circular…

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Janet Thornton retires: a pioneer in structural bioinformatics

In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments shaping the field of bioinformatics Professor Dame Janet Thornton. Credit: EMBL Professor Dame Janet Thornton is one of the world’s pioneers in structural bioinformatics. Her incredible career and active voice on many topics, including science…

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Postdoctoral Researcher in Bioinformatics – University of Oxford – job portal

UK date and time: 07-June-2023 17:48 &nbsp Applicant Options New Search Login Job Details Help Terms of Use & Privacy Policy &nbsp Job Details Postdoctoral Researcher in Bioinformatics Department of Oncology, Weatherall Institute of Molecular Medicine, Headington, Oxford, OX3 9DS About the role Applications are invited from enthusiastic, motivated individuals…

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Shotgun Sequencing of Small Intestine Reveals Species Tied to GI Symptom Severity

At the annual Digestive Disease Week conference, researchers reported results on the first luminal shotgun sequencing of the small intestine, which identified specific strains of Escherichia coli and Klebsiella in small intestinal bacterial overgrowth (SIBO) linked to gastrointestinal symptom severity. In this exclusive MedPage Today video, Gabriela Leite, PhD, the…

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Advances in the Understanding of DLBCL Immunology Could Spark Novel Therapies

The development of new therapies and new technologies is leading to a better understanding of the immunology of diffuse large B-cell lymphoma (DLBCL), according to a new review. The article, published in the journal Cancers, outlines the latest insights and their implications for patient care. Corresponding author Taishi Takahara, MD,…

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Telehealth-Based Clinical Trial for Pancreatic Cancer Is Launching

Credit: KATERYNA KON/SCIENCE PHOTO LIBRARY/Getty Images The post-COVID rise of telemedicine has spawned a unique trial that will give more patients access to targeted therapies for pancreatic cancer, but from the comfort of their home. An entirely telehealth-based cancer clinical trial is being launched at The Ohio State University Comprehensive Cancer…

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Postdoctoral Research Fellow position: Biomechanics during metamorphosis in the protochordate Ciona

About The University of Bergen (UiB)  The University of Bergen is a renowned educational and research institution, organised into seven faculties and approximately 54 institutes and academic centres. Campus is located in the centre of Bergen with university areas at Nygårdshøyden, Haukeland, Marineholmen, Møllendalsveien and Årstad.  The Michael Sars Centre is…

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Milvexian, FXIa Inhibitor, Wins US FDA Fast Track Designation for 3 Indications in Phase 3 Trial Program

©santoelia/stock.adobe.com The FDA has granted fast track designation for 3 prospective indications for milvexian, an investigational oral factor Xla inhibitor, in joint development by Janssen Pharmaceutical and Bristol Myers Squibb. The indications are stroke prevention after an acute ischemic stroke or high-risk transient ischemic attack, recent acute coronary syndrome, and atrial…

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Principal Scientist I Bioinformatics Job Opening in Santa Clara, CA at Roche Holdings Inc.

The Position Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist in the NGS Algorithms and Applications team to…

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Nucleai hiring Bioinformatics Research Scientist in Chicago, IL, US

About Nucleai Nucleai improves the cancer diagnostics process (tissue biopsies inspections, Pathology) to be more efficient, accurate and consistent through applying innovative Machine Learning and Machine Vision Algorithms. Nucleai has the vision of enabling personalized treatment, improve procedures (on-site) and provide better classification for Oncology. Job Description We are hiring…

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Large scale proteomic studies create novel privacy considerations

Funding Support and Acknowledgements: COPDGene: The project described was supported by Award Number U01 HL089897 and Award Number U01 HL089856 from the National Heart, Lung, and Blood Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung,…

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Senior Bioinformatics Analyst – School of Medicine, Biomedical Engineering Job Opening in Decatur, GA at Emory

Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribute to the diversity and excellence of our academic community. JOB DESCRIPTION: Maintains software, hardware and information networks in a bioinformatics and…

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View All Jobs/Careers – Emory Healthcare/Emory University Assistant Bioinformatics Scientist

Discover Your Career at Emory University Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribute to the diversity and excellence of our academic community. Description The Department of Orthopaedics at…

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Deloitte Consulting hiring BioInformatics Data Scientist in Atlanta, Georgia, United States

Position Summary Bioinformatics Data Scientist In this age of disruption, organizations need to navigate the future with confidence by tapping into the power of data analytics, robotics, and cognitive technologies such as Artificial Intelligence (AI). Our Strategy & Analytics portfolio helps clients leverage rigorous analytical capabilities and a pragmatic mindset…

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Ginkgo Bioworks Senior Bioinformatics Engineer

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Ginkgo Bioworks…

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Erdafitinib Bests Chemotherapy in FGFR-Altered Metastatic Urothelial Carcinoma

Erdafitinib improves survival outcomes when compared to chemotherapy in patients with metastatic urothelial carcinoma and select FGFR alterations who were previously treated with immune checkpoint inhibitors, according to results from the phase 3 THOR trial.  These results support erdafitinib as a standard of care option for these patients and support…

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Integrated Resources, Inc ( IRI ) hiring Computational Biologist/Bioinformatician in Mississauga, Ontario, Canada

This contract position provides the opportunity to implement and deliver bioinformatics tools for a wide range of applications working with proteomics. The candidate will join a team focused on infrastructure developments for proteomics and collaboration with many research groups in Genentech, working with both bioinformatics and bench biology teams. Responsibilities…

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Associate Professor, Ecology

The Department of Biological Sciences at the University of Toronto Scarborough (UTSC) invites applications for a full-time tenure stream position in Ecology. The appointment will be at the rank of Associate Professor with an expected start date of January 1, 2024, or shortly thereafter. This search aligns with the University’s…

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AI Algorithms Outperform Standard Model of Predicting Five-Year Risk for Breast Cancer

Credit: gorodenkoff/Getty Images A retrospective study using thousands of two-dimensional mammograms performed at Kaiser Permanente Northern California showed that five separate AI algorithms outperformed the standard clinical model of predicting five-year risk for breast cancer. Women’s risk for developing breast cancer uses clinical models such as the Breast Cancer Surveillance…

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Carvykti outperforms standard care as earlier line of therapy: Analysis

Carvykti (ciltacabtagene autoleucel) significantly reduces the risk of disease progression or death in adults with multiple myeloma who received one to three prior lines of therapy and failed to respond to standard Revlimid (lenalidomide). That’s according to the first data analysis, at nearly 1.5 years of follow-up, of the ongoing…

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Biogen and Denali Terminate Phase 3 LIGHTHOUSE Study of BIIB122 in LRRK2-related Parkinson Disease

Samantha B. Haeberlein, PhD Biogen and Denali have announced that they are discontinuing a portion of the clinical development program for BIIB122 (also known as DNL151), an investigational small molecule inhibitor of LRRK2 in development for the treatment of Parkinson disease (PD). As a result of this decision, the phase…

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Postdoctoral Associate- Brain Tumor Bioinformatics job with Baylor College of Medicine

Summary A postdoctoral position is immediately available in the Taylor laboratory to study, plan, direct and conduct specialized and advanced research experiments with Neuro oncology research program. This position will be responsible for evaluation and analyzing data. Job Duties Designs and performs experimental studies that directly answer the above research…

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why are bioinformatics salaries so low

As the field of personalized medicine continues to grow, the need for advanced computational tools and machine learning algorithms to analyze and interpret large-scale molecular data is increasing. Here, bioinformaticians are needed to perform tasks such as: Since bioinformatics is very research-oriented and jobs in industry are few, many graduates…

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Elucidata Bioinformatics Scientist Job For MSc & PhD Bioinformatics, Comp Bio, Biotech

Home – Elucidata Bioinformatics Scientist Job For MSc & PhD Bioinformatics, Comp Bio, Biotech Elucidata Bioinformatics Scientist Job For MSc & PhD Bioinformatics, Comp Bio, Biotech Senior Bioinformatics Scientist About the job Your Role: Elucidata is seeking a bioinformatics enthusiast for the role of Senior Bioinformatics Scientist. In this role, you will…

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NIRF Ranking 2023: IIT Guwahati Maintained 7th Rank in ‘Engineering’ Category

NEW DELHI: In the National Institutional Ranking Framework (NIRF), Indian Institute of Technology Guwahati has successfully maintained its status and this year placed seventh in the engineering category. This year, IIT Guwahati placed ninth in both the “Overall” and the “Research” categories. Taking on Twitter, IIT Guwahati informed that, “@IITGuwahati…

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Erdafitinib Confers OS Benefit in FGFR-Altered Urothelial Cancer

Erdafitinib (Balversa) reduced the risk of death by 36% vs investigator’s choice of chemotherapy in patients with FGFR2/3-altered metastatic urothelial cancer who were previously treated with anti–PD-1 therapy, according to findings from the phase 3 THOR trial (NCT03390504). The results were presented in a late-breaking abstract session during the 2023…

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Erdafitinib Reduces Risk of Death by 36% in FGFR-Altered Urothelial Cancer

Patients with FGFR2/3-altered metastatic urothelial cancer who were previously treated with anti–PD-1 therapy experienced a 36% reduction in the risk of death following treatment with Erdafitinib (Balversa) vs investigator’s choice of chemotherapy. The results were presented in a late-breaking abstract session during the 2023 ASCO Annual Meeting by Yohann Loriot,…

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Postdoc – Giustacchini Group job with Human Technopole

APPLICATION CLOSING DATE:  30th of June 2023 Human Technopole (HT) is a new interdisciplinary life science research institute, created and supported by the Italian government, with the aim of developing innovative strategies to improve human health. In this context the Giustacchini group at the Population and Medical Genomics Centre is looking for a…

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Erdafitinib extends survival in post-immunotherapy, FGFR-altered urothelial cancer

Findings form the phase 3 THOR trial (NCT03390504) presented during the 2023 ASCO Annual Meeting showed that erdafitinib (Balversa) significantly improved overall survival compared with investigator’s choice of chemotherapy in patients with FGFR2/3-altered metastatic urothelial cancer who had previously received an anti–PD-(L)1 therapy.1 “The phase 3 THOR study supports the…

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Open PhD position in Bioinformatics

München   The Beltrán and Kerschensteiner Labs at the Biomedical Center of the Ludwig-Maximilians University Munich are looking for a PhD student in Bioinformatics. The candidate will develop bioinformatic methods for integrative analysis of scRNA-seq and snRNA-seq datasets from multiple sclerosis (MS) human samples and related MS models. Such integrative…

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Bioinformatics Faculty – University of North Carolina at Chapel Hill – job portal

Skip to Main Content Bioinformatics Faculty Bookmark this Posting Please see Special Instructions for more details. Please upload the names and contact information for four (4) references. A summary of career goals should be uploaded as the required “Other Document.” Posting Information Posting Information Department Pathology Lab Med – Research…

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KEGG T01001: 57661

Entry 57661             CDS       T01001                                  Symbol PHRF1, PPP1R125, RNF221 Name (RefSeq) PHD and ring finger domains 1   KO K17586   PHD and RING finger domain-containing protein 1 Organism hsa  Homo sapiens (human) Brite KEGG Orthology (KO) [BR:hsa00001] 09180 Brite Hierarchies  09181 Protein families: metabolism   01009 Protein phosphatases and associated proteins [BR:hsa01009]    57661 (PHRF1)Protein phosphatases and associated proteins [BR:hsa01009] Protein serine/threonine…

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Collaborative Care and Patient Education Driving AD Treatment Pathways

Casey Butrus, PharmD: Thank you all for this rich and informative discussion. Before we conclude, I’d like to get some final thoughts from each of you. I’ll start with Amy. Amy Brennan: My final thoughts are I think it’s key for all of us to work together as the prescriber,…

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how to export data from rstudio to excel

You need to write the path of the file in the function drop_delete(), We can summarize all the functions in the table below, Copyright – Guru99 2023 Privacy Policy|Affiliate Disclaimer|ToS, How to Export a DataFrame to a CSV File in R, How to Export a Data from R to Excel…

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CEDARS-SINAI Postdoctoral Scientist – Bioinformatics and Integrative Genomics Research Cluster in Sacramento, CA | 844690591

At Cedars-Sinai,postdoctoral scientists and other junior researchers fulfill a critical role inexpanding the horizons of medical knowledge through biomedical research. Byhosting more than 100 postdocs, who conduct vital research and receive advancedtraining with expert faculty mentors, Cedars-Sinai supports theongoing medical education process that continues beyond PhD/MD graduation.   Overview: Bioinformaticsand Integrative Genomics  …

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Five Clinical-Stage Cell and Gene Therapy Startups Leading the Pack

Credit: Crystal light/Adobe Stock After decades of research, cell and gene therapies are gaining traction in the biotech industry. Here are five investor-favored private startups with products already in clinical development. While conventional medications are often effective at controlling symptoms or modifying a disease, there are many conditions where their…

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Split-dose R-CHOP regimen effective for older adults with newly diagnosed lymphoma

Source/Disclosures Published by: Source: Shah NN, et al. Abstract 7554. Presented at: ASCO Annual Meeting; June 2-6, 2023; Chicago. Disclosures: Adaptive Biotechnology and a grant from the Froedtert Foundation supported this study. Shah reports consultant/advisory board roles with, research funding/paid expenses from or stock ownership in Adaptive…

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Osimertinib shows promising phase-3 results for non-small cell lung cancer

Newswise — Researchers at Yale School of Medicine have presented findings from an international late-stage clinical trial that shows the targeted therapy osimertinib improved rates of survival and reduced risk of recurrence in patients with non-small cell lung cancer following surgery. The ADUARA study found 88% of patients with stage…

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Phase 3 trial results of HAE therapy donidalorsen due in 2024

Ionis Pharmaceuticals has finished enrollment in a Phase 3 clinical trial testing the ability of its experimental therapy donidalorsen to prevent swelling attacks in people with hereditary angioedema (HAE) types 1 or 2. Results from the placebo-controlled study, dubbed OASIS-HAE (NCT05139810), are expected in the first half of 2024. If…

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CORRECTING and REPLACING Variant Bio Turns Toward Discovery of Novel Medicines, Marking a New Chapter of Growth for the Company

David Moller joins as Chief Scientific Officer and Steve Bryant as Chief Business Officer, adding deep expertise to executive team SEATTLE–(BUSINESS WIRE)–Please replace the release with the following corrected version due to multiple updates. The updated release reads: VARIANT BIO TURNS TOWARD DISCOVERY OF NOVEL MEDICINES, MARKING A NEW CHAPTER…

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Element Enters the European Genomics Market with New Customers and a Growing Team

SAN DIEGO and AMSTERDAM, June 5, 2023 /PRNewswire/ — Element Biosciences, Inc., the developer of the Element AVITI™ System, an innovative DNA sequencing platform disrupting genomics, is pleased to announce that the AVITI is now available in Europe, in addition to Asia and the Middle East. VIB, Flanders’ leading life…

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Average Bioinformatics Technician Salary in Fujian, China for 2023

In this article, we will look at the average Bioinformatics Technician salary for 2023 in Fujian and how that compares to other countries and professions. We’ll also look at interesting salary data points like median salary, 25th and 75th percentile salaries, salary amounts based on experience, bonus ranges and more!…

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Natera Announces Data from the

Natera%2C+Inc. (NASDAQ: NTRA), a global leader in cell-free DNA testing, today announced new data on its Prospera test being presented at the American Transplant Congress (ATC) 2023 taking place June 3-7, 2023. The presentations include several interim analyses from ProActive, a prospective donor-derived cell-free DNA (dd-cfDNA) study evaluating Natera’s Prospera…

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Post-Doctoral Fellowship In Bioinformatic To Investigate Tumor Heterogeneity

16 May 2023 Job Information Organisation/Company INSERM DR Paris 6 Research Field Medical sciences » Cancer research Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Country France Application Deadline 1 Sep 2023 – 20:00 (Europe/Paris) Type of Contract Temporary Job Status Full-time Hours Per Week 38.5 Offer Starting Date…

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Talazoparib Plus Enzalutamide Manageable With Dose Modification Strategy in mCRCPC

Arun Azad, MBBS, PhD, FRACP In patients with metastatic castration-resistant prostate cancer (mCRPC) treated in the phase 3 TALAPRO-2 study (NCT03395197), the combination of talazoparib plus enzalutamide (Xtandi) appeared to be manageable with dose modifications or supportive care, according to a 2023 ASCO Annual Meeting presentation.1 “TALAPRO-2 is the first…

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Talazoparib/enzalutamide combo shows manageable safety profile in mCRPC

Combination talazoparib plus enzalutamide was found to be generally manageable with dose modifications or standard supportive care in the treatment of men with metastatic castration-resistant prostate cancer (mCRPC), according to safety results from the phase 3 TALAPRO-2 study (NCT03395197).1 Patients in the phase 3 TALAPRO-2 study were randomized 1:1 to…

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Postdoctoral Fellows/Research scientists job with University of Michigan

We are seeking for highly motivated postdoctoral fellows to join in Dr. Thanh Hoang?s lab in the University of Michigan. Our research encompasses a wide range of neuroscience research and functional genomics, ineurodevelopment and neurodegeneration and glial biology. Using a combination of large-scale multiomics and genetic tools in both mouse…

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Rangam hiring Bioinformatics Analyst (RNA-Seq/R Coding/Linux/RNA-Seq) (Phd) in United States

Remote role Title – Bioinformatics Analyst We have an exciting contract opportunity for a Bioinformatics Analyst with extensive experience in designing and implementing bioinformatics methods as well as analysis and interpretation of various types of omics data to solve biological and clinical problems. The candidate should be familiar with developing…

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Senior Scientist/ Scientist, Bioinformatics at Fate Therapeutics, Inc.

Fate Therapeutics is looking for a Senior Scientist or Scientist with expertise in bioinformatics to join the Molecular Engineering team.    The primary focus for this position will be to independently develop, optimize, and implement NGS pipelines to support advancement of Fate’s gene editing platform. The position will also establish, modify,…

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Bioinformatics Scientist job with Rush University

Job Title: Bioinformatics Scientist Department: Research Core-Research Administration Shift: 1st Full/Part: Active Regular FT (72 to 80 hours per pay period) Specialty: Bioinformatics Job Number: Job Description: Bioinformatics Scientist This position is responsible for the integrative analysis of high throughput genomic data, and work with computational and laboratory-based investigators to…

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Bioinformatics Analyst II – Seibold Lab job with National Jewish Health

The Seibold Laboratory is a cutting-edge, NIH funded, laboratory focused on elucidating the pathobiological basis of asthma and other complex lung and allergic diseases. Our goal is to discover pathobiological subgroups of disease (termed disease endotypes) and the genetic, environmental, and immune factors driving their development. We are accomplishing these…

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Bioinformatics Analyst (PhD) – Rangam

Remote role Title – Bioinformatics Analyst We have an exciting contract opportunity for a Bioinformatics Analyst with extensive experience in designing and implementing bioinformatics methods as well as analysis and interpretation of various types of omics data to solve biological and clinical problems. The candidate should be familiar with developing…

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Postdoctoral Research Associate in bio-ontologies and machine learning (Imageomics)

The Renaissance Computing Institute (RENCI) at UNC Chapel Hill is seeking a Postdoctoral Research Associate to assist with research involved in an NSF Harnessing the Data Revolution Institute project entitled Imageomics: A New Frontier of Biological Information Powered by Knowledge-Guided Machine Learning. Work on the project at RENCI involves developing…

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People in the News at Illumina, Pacific Biosciences, Myriad Genetics, Delfi Diagnostics, More

Illumina: Stephen MacMillan, Scott Ullem Illumina has added Hologic CEO Stephen MacMillan and Scott Ullem, CFO of Edwards Lifesciences, to its board of directors, effective immediately. MacMillan will also serve as non-executive chair of the board. The moves come just a week after shareholders voted to replace previous chair John…

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Epic voyage finds astonishing microbial diversity among coral reefs

The samples were collected during some 3,000 dives by scientists aboard research vessel Tara.Credit: Pete West/Tara Ocean Foundation The largest-ever survey of Pacific Ocean corals has found that there’s likely to be more genetic diversity in the world’s coral reefs than researchers previously thought. This assessment is based on a…

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Allos plans for pivotal Phase 3 study of arbaclofen for fragile X | Positive findings in trial would support applications for FDA approval

Allos Pharma has met with the U.S. Food and Drug Administration (FDA) to optimize the design of a planned Phase 3 trial to test its investigational oral therapy arbaclofen in individuals with fragile X syndrome. The trial is intended to confirm promising findings from a previous Phase 3 study in children…

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Rare Mutations Confer Risk of Common Diseases

Credit: CIPhotos / iStock An AI-powered study has revealed that rare, penetrant genetic mutations confer ten times the risk of everyday diseases compared with common variants in the same genes. Among nearly half a million people studied, nearly all carried at least one rare, penetrant mutation for conditions that ranged…

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Bioinformatics Lead job with Delson Talent Consulting

Bioinformatics Lead Newton, MA (remote ok) Our Client is a Series A, pre-commercial, biotechnology company committed to saving lives through the early detection of cancer. They are looking for a passionate individual to lead Computational Biology for their R&D organization. This individual will play a critical role in the development…

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Research Fellow in Ophthalmology job with UNIVERSITY OF SYDNEY

Great opportunity to contribute to a research project focused the detection and repair of sick retinal ganglion cells Full time, 3 year fixed term Base Salary $113,184 + 17% superannuation About the opportunity The Save Sight Institute (SSI) is a Centre of The University of Sydney,…

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Steep LDL Cholesterol Reductions With ANGPTL3 siRNA in HoFH

MANNHEIM, Germany — A novel drug that targets production of a liver protein involved in lipid metabolism appears to markedly reduce low-density lipoprotein (LDL) cholesterol levels for patients with homozygous familial hypercholesterolemia (HoFH), suggest results from the phase 2 GATEWAY trial. The research was presented at the European Atherosclerosis Society…

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Sobi to present new data at the 2023 EHA congress

Sobi® will present data at the EHA (European Haematology Association) hybrid congress taking place in Frankfurt, Germany 8-11 June, 2023, highlighting the company’s commitment in rare haematological diseases. During the congress, Sobi will present important new data on haemophilia, immune thrombocytopenia, relapsed or refractory diffuse large b-cell lymphoma (DLBCL), and…

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Scientists develop probe to push for new drug discoveries

A study by Loughborough University and the University of Oxford in the U.K. has led to the development of a small molecule probe that could deepen the understanding of a crucial cellular messenger and lead to the development of new therapeutic drugs. The research paper showcases the researchers’ innovative probe…

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Postdoc/PhD research positions in ML/Stats and Bioinformatics

Dear all,   I have two openings for the following research positions, both with application deadline of 18 June 2023 (ongoing selection):   PhD or Postdoc on multimodal machine learning for molecular maps of human tissue in health & disease. Some topics of interest include (spatial) (single-cell) multi-omics…

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Studying primates sheds light on causes of common diseases

By Mark Waghorn via SWNS Millions of mutations behind modern human diseases have been identified by studying the fossilized remains of our primitive ancestors. Scientists mapped the DNA of over 800 individuals from 233 primate species – almost half of which still exist on Earth. It increases the number of…

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Senior Scientist, Analytical Sciences in Gaithersburg, Maryland

Do you have a passion for science? Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you! At AstraZeneca, we put patients first and strive to meet their unmet needs…

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Addressing Cell Therapy Challenges Through a Modular, Closed, and Automated Manufacturing System

Over the past decade, a large portion of the resources dedicated to scientific research has been focused on solving widespread unmet medical needs. This is particularly true within cancer, where many patients have limited treatment options. One of the most promising treatment approaches, which is equally as complex as cancer,…

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Massive Reference Genome Project Characterizes Primate Variation

The need for a more complete understanding of primate genetic diversity is urgent, especially given the threats posed by factors such as climate change, habitat loss, and illegal trading and hunting. Characterizing primate variation not only allows us to better understand and conserve these species in the wild, but it…

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Parkinson’s Disease Drug Slows ALS Progression in Clinical Trial

An early clinical trial headed by researchers at Keio University School of Medicine has shown that the Parkinson’s disease drug ropinirole is safe to use in patients with the fatal motor neuron disease amyotrophic lateral sclerosis (ALS), and delayed disease progression by an average of 27.9 weeks. The study demonstrated…

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Frederick National Laboratory Bioinformatics Manager in Frederick, MD | 843725672

Bioinformatics Manager Job ID: req3574Employee Type: exempt full-timeDivision: Bioinformatics and Computational ScienceFacility: Frederick: Ft DetrickLocation: PO Box B, Frederick, MD 21702 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The…

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DELFI Diagnostics Appoints David Morgenstern, PhD, as VP of Clinical Development

Dave Morgenstern, PhD DELFI Diagnostics, a pioneering developer of a new class of high-performance, accessible liquid biopsy tests for early cancer detection and monitoring, has hired Dave Morgenstern, PhD, as Vice President of Clinical Development. Dave joins DELFI from Roche Diagnostics, where he spent more than a decade in clinical development…

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LSU Researchers Show Mobile Elements Monkeying Around the Genome

Mark Batzer is an elected fellow of the American Association for the Advancement of Science and a National Academy of Inventors senior member. His research at LSU has been supported by multiple federal and state agencies, including the National Institutes of Health, the National Science Foundation and the Louisiana Board…

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Senior Bioinformatics Research Scientistt/Bioinformatics Research Scientist-Epigenetics(USA, Memphis, TN, St. Jude Children’s Research Hospital)

Families never receive a bill from St. Jude! That’s what we are famous for. Click to Apply and send CV to beisi.xu[at]stjude.org Overview The Epigenetics Group from the Center for Applied Bioinformatics at St. Jude Children’s Research Hospital is looking for a highly motivated and creative Bioinformatics Research Scientist or…

Continue Reading Senior Bioinformatics Research Scientistt/Bioinformatics Research Scientist-Epigenetics(USA, Memphis, TN, St. Jude Children’s Research Hospital)

Research Fellow on Bioinformatics and AD Microbiome Modelling job with UNIVERSITY OF SURREY

Civil & Enviromental Engineering Location:  Guildford Salary:  £35,308 to £43,155 per annum Fixed Term Post Type:  Full Time Closing Date:  23.59 hours BST on Wednesday 21 June 2023 Reference:  028423 This project “AI for Net Zero” aims to rapidly transform the anaerobic digestion (AD) industry into a data-driven, digitalised sector, to accelerate…

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“Deep Sequencing” Identifies Several New Genetic Variants in Vascular Anomalies

Advanced “deep sequencing” of patients’ genomes by Children’s Hospital of Philadelphia (CHOP) researchers has unveiled previously undetected genetic variants connected to vascular anomalies. The discovery led to tailored therapies, improving the condition of over 60% of patients and paving the way for future non-invasive diagnostic techniques for such life-threatening conditions….

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Postdoctoral Research Fellow at University of Exeter

The new full-time post is available from the 1st of August 2023 until the 30th of April 2025 on a fixed term basis. This role offers the opportunity for hybrid working – some time on campus and some from home. We welcome applications from candidates interested in working part-time hours…

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Bioinformatics Manager Job in Maryland (MD), $vacancy_industry Career, Full Time Jobs in Frederick National Laboratory for Cancer Research

Bioinformatics Manager Job ID: req3574Employee Type: exempt full-timeDivision: Bioinformatics and Computational ScienceFacility: Frederick: Ft DetrickLocation: PO Box B, Frederick, MD 21702 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc….

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PhD Position for the Project Autonomous Marine Biodiversity Mapping and Bioprospecting Platform job with NORWEGIAN UNIVERSITY OF SCIENCE & TECHNOLOGY – NTNU

About the job The AMBIOS project aims to develop the world’s first fully autonomous platform for multi-layer mapping of biodiversity in the ocean. Autonomous marine vessels will be equipped with sensors for physicochemical characterization, instruments for automated water sampling, and an underwater video recording system for AI-based detection of macroscopic…

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Buccal Swab Added as WGS Sample Collection Option

GeneDx announced the availability of its GenomeXpress and GenomeSeqDx whole genome sequencing (WGS) tests with buccal swabs as an alternative sample collection option for biological parents or other immediate family members. Sequencing biological parent genomes alongside patient genomes—known as trio analysis—aids in disease diagnosis and greatly increases diagnostic yield rates. “We…

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Marstacimab lowered bleed rates in hemophilia in Phase 3 trial | Weekly treatment found effective for patients without inhibitors

Weekly treatment with the experimental therapy marstacimab (PF-06741086) was found to significantly reduce bleed rates for adult and adolescent hemophilia A and B patients without inhibitors relative to standard therapies. In so doing, it met the main goal of the pivotal Phase 3 BASIS clinical trial, designed to evaluate the…

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Liquid biopsy test may detect early-stage and low DNA-shedding cancers | VUMC Reporter

  A liquid biopsy-based multicancer early detection (MCED) test could detect 12 types of cancers, including low DNA-shedding cancers and early-stage cancers, according to data from a retrospective study presented at the AACR Annual Meeting 2023, held recently in Orlando, Florida. “Detection of cancer in early stages through screening programs…

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Mapping the Exposome To Prevent Disease | Johns Hopkins

Toxicology—the study of poisons—is due for an overhaul. The underlying methodologies of the discipline, which have remained largely stagnant for more than 50 years, are inadequate in terms of cost, time, throughput, animal use, and relevance of the results to humans, says Thomas Hartung, MD, PhD. A working group commissioned…

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