Tag: provean

Ethnic Diversity of DPD activity and the DPYD Gene

Plain Language Summary Fluoropyrimidine (FP; 5-FU, capecitabine) is a common chemotherapy used to treat many different cancers, including cancer of the colon and rectum, upper digestive tract, breast and head and neck. Cancer patients who receive FP chemotherapy are at risk of developing severe side effects from their treatment. A…

Continue Reading Ethnic Diversity of DPD activity and the DPYD Gene

Provean for mutations in yeast genome

Provean for mutations in yeast genome 0 Hi everyone, I am currently working on anti-fungal drug resistance mutations on a medically important yeast. I have listed some of the well-known mutations. Then use Provean web application to test whether Provean is able to sort them. I had very promising results…

Continue Reading Provean for mutations in yeast genome

PROVEAN input script

PROVEAN input script 1 Hi everyone, I would like to write a python script to extract amino acid substitutions and indels from several protein alignments, and use it as an input for variant effect prediction with PROVEAN. So far I have modified an initial script (C: How to extract polymorphic…

Continue Reading PROVEAN input script

PROVEAN not working

PROVEAN not working 2 Hello All, I’m having troubles making PROVEAN work. I’m getting this error while trying to run PROVEAN /gpfs01/home/x/NCBI-BLAST/blastdb/ftp.ncbi.nih.gov/blast/db/nr [17:44:08] searching related sequences… [18:45:32] clustering subject sequences… ./provean.sh: line 187: 41879 Segmentation fault $COMMAND Any idea what I’m doing wrong? provean • 652 views • link updated…

Continue Reading PROVEAN not working