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Ants of French Guiana: 16S rRNA sequence dataset
doi: 10.3897/BDJ.11.e91577. eCollection 2023. Affiliations Expand Affiliations 1 UMR Écologie des Forêts de Guyane (AgroParisTech, CIRAD, CNRS, INRAE, Université de Guyane, Université des Antilles), Kourou, French Guiana UMR Écologie des Forêts de Guyane (AgroParisTech, CIRAD, CNRS, INRAE, Université de Guyane, Université des Antilles) Kourou French Guiana. 2 Laboratoire Evolution et…
Preparation and recognition mechanism study of an scFv targeting chloramphenicol for a hybridization chain reaction-CRISPR/Cas12a amplified fluoroimmunoassay
. 2024 Mar 8:1293:342283. doi: 10.1016/j.aca.2024.342283. Epub 2024 Jan 22. Affiliations Expand Affiliations 1 College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China. 2 Medical College, Nankai University, Tianjin, 300500, China. Electronic address: wangshuo@nankai.edu.cn. 3 College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China….
Antimicrobial potential of Streptomyces coeruleofuscus SCJ isolated from microbiologically unexplored garden soil in Northwest Morocco
Zaman, S. B. et al. A review on antibiotic resistance: Alarm bells are ringing. Cureus doi.org/10.7759/cureus.1403 (2017). Article PubMed PubMed Central Google Scholar Peterson, E. & Kaur, P. Antibiotic resistance mechanisms in bacteria: Relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens. Front. Microbiol. 9, 2928 (2018)….
Sperm-specific histone H1 in highly condensed sperm nucleus of Sargassum horneri
Cho, C. et al. Haploinsufficiency of protamine-1 or-2 causes infertility in mice. Nat. Genet. 28, 82–86 (2001). Article CAS PubMed Google Scholar Oliva, R. Protamines and male infertility. Hum. Reprod. Update 12, 417–435 (2006). Article CAS PubMed Google Scholar Balhorn, R. The protamine family of sperm nuclear proteins. Genome Biol….
SMAD4 variants and its genotype-phenotype correlations to juvenile polyposis syndrome
Abstract BACKGROUND: Juvenile polyposis syndrome (JPS), a rare autosomal dominant syndrome, affects one per 100 000 births, increasing lifetime cancer risk by 9 – 50%. Around 40-60% of JPS cases are caused by disease-causing variants (DCV) in SMAD4 or BMPR1A genes, of which SMAD4 accounts for 20-30%. OBJECTIVES: To characterise…
Community-scale models of microbiomes: Articulating metabolic modelling and metagenome sequencing
Review doi: 10.1111/1751-7915.14396. Online ahead of print. Affiliations Expand Affiliations 1 Quadram Institute Bioscience, Norwich, UK. 2 Earlham Institute, Norwich, UK. 3 Inria, University of Bordeaux, INRAE, Talence, France. 4 University of Bordeaux, CNRS, Bordeaux INP, LaBRI, UMR 5800, Talence, France. 5 INRAE STLO¸University of Rennes, Rennes, France. 6 INRAE,…
Genomic insights into Plasmodium vivax population structure and diversity in central Africa | Malaria Journal
Hamblin MT, Di Rienzo A. Detection of the signature of natural selection in humans: evidence from the Duffy blood group locus. Am J Hum Genet. 2000;66:1669–79. Article CAS PubMed PubMed Central Google Scholar Hamblin MT, Thompson EE, Di Rienzo A. Complex signatures of natural selection at the Duffy blood group…
N6-methyladenosine modification positively regulate Japanese encephalitis virus replication | Virology Journal
Burgess HM, Depledge DP, Thompson L, Srinivas KP, Grande RC, Vink EI, Abebe JS, Blackaby WP, Hendrick A, Albertella MR, Kouzarides T, Stapleford KA, Wilson AC, Mohr I. Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication. Genes Dev. 2021;35:1005–19. Article CAS PubMed PubMed Central Google Scholar Chambers…
Causality-enriched epigenetic age uncouples damage and adaptation
Gladyshev, V. N. et al. Molecular damage in aging. Nat. Aging 1, 1096–1106 (2021). Article PubMed PubMed Central Google Scholar Sziráki, A., Tyshkovskiy, A. & Gladyshev, V. N. Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction. Aging Cell 17, e12738 (2018). Article PubMed …
A system review and meta-analysis
The microenvironment of diffuse large B-cell lymphoma (DLBCL) is composed of various components, including immune cells and immune checkpoints, some of which have been correlated with the prognosis of DLBCL, but their results remain controversial. Therefore, we conducted a systematic review and meta-analysis to investigate the association between the microenvironment…
Comparison of capture-based mtDNA sequencing performance between MGI and illumina sequencing platforms in various sample types | BMC Genomics
Hu T, Chitnis N, Monos D, Dinh A. Next-generation sequencing technologies: an overview. Hum Immunol. 2021;82(11):801–11. Article CAS Google Scholar Jeon SA, Park JL, Park SJ, Kim JH, Goh SH, Han JY, Kim SY. Comparison between MGI and Illumina sequencing platforms for whole genome sequencing. Genes Genomics. 2021;43(7):713–24. Article CAS …
Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis
CDC. (ed CDC) (U.S. Department of Health and Human Services, CDC; 2019, Atlanta, GA, 2019). Krismer, B., Weidenmaier, C., Zipperer, A. & Peschel, A. The commensal lifestyle of Staphylococcus aureus and its interactions with the nasal microbiota. Nat. Rev. Microbiol. 15, 675–687 (2017). Article CAS PubMed Google Scholar Somerville, G….
CRISPR-Cas12a base editors confer efficient multiplexed genome editing in rice.
Addgene: CRISPR-Cas12a base editors confer efficient multiplexed genome editing in rice. More than 20 requests More than 50 requests More than 100 requests Item added to cart. Cart quantity updated. Limit per order. Item already in cart. Could not add item to cart. Skip to main content CRISPR-Cas12a base editors…
Plug-and-play smart transistor bio-chips implementing point-of-care diagnosis of AMI with modified CRISPR/Cas12a system
. 2024 Feb 15:246:115909. doi: 10.1016/j.bios.2023.115909. Epub 2023 Dec 5. Affiliations Expand Affiliations 1 School of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan, 430065, PR China; Department of Pharmacy, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, PR China. 2 School of Laboratory…
A potential savior for aging cartilage and osteoarthritis
A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 15, Issue 23, entitled, “Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes.” While advanced age is widely recognized as the greatest…
High-sensitivity two-color detection of double-stranded DNA with a confocal fluorescence gel scanner using ethidium homodimer and thiazole orange
High-sensitivity two-color detection of double-stranded DNA with a confocal fluorescence gel scanner using ethidium homodimer and thiazole orange – Texas A&M University (TAMU) Scholar Search form Overview Research Identity Additional Document Info Other View All Overview abstract Ethidium homodimer (EthD; lambda Fmax 620…
Neutrophil extracellular trap-induced intermediate monocytes trigger macrophage activation syndrome in adult-onset Still’s disease | BMC Medicine
Wang MY, Jia JC, Yang CD, Hu QY. Pathogenesis, disease course, and prognosis of adult-onset Still’s disease: an update and review. Chin Med J (Engl). 2019;132(23):2856–64. Article CAS PubMed Google Scholar Feist E, Mitrovic S, Fautrel B. Mechanisms, biomarkers and targets for adult-onset Still’s disease. Nat Rev Rheumatol. 2018;14(10):603–18. Article …
Notch signaling in thyrocytes is essential for adult thyroid function and mammalian homeostasis
Brent, G. A. Mechanisms of thyroid hormone action. J. Clin. Invest. 9, 3035–3043 (2012). Article Google Scholar Iwen, K. A., Oelkrug, R. & Brabant, G. Effects of thyroid hormones on thermogenesis and energy partitioning. J. Mol. Endocrinol. 60, R157–R170 (2018). Article PubMed CAS Google Scholar Biondi, B. & Wartofsky, L….
Mitochondrial replication’s role in vertebrate mtDNA strand asymmetry
. 2023 Dec;13(12):230181. doi: 10.1098/rsob.230181. Epub 2023 Dec 20. Affiliations Expand Affiliations 1 CIIMAR/CIMAR – Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Matosinhos, Portugal. 2 Programa de Doctorado ‘Ciencias marinas, Tecnología y Gestión’ (Do*MAR), Universidad de Vigo, Vigo, Spain. 3 Centro Oceanográfico de Vigo (COV), Instituto Español…
GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners
doi: 10.1093/nar/gkad1202. Online ahead of print. Nidhi Kanwal 1 , Nicolai Krogh 2 , Indira Memet 1 , Nicolas Lemus-Diaz 1 , Chairini C Thomé 1 , Luisa M Welp 3 4 , Athanasia Mizi 5 , Philipp Hackert 1 , Argyris Papantonis 5 , Henning Urlaub 3 4 6 7 , Henrik Nielsen 2 , Katherine…
Enhancing Human Glycoprotein Hormones Production in CHO Cells Using Heterologous Beta-Chain Signal Peptides
Jackson, R.C. and Blobel, G., Post-translational processing of full-length presecretory proteins with canine pancreatic signal peptidase, Ann. N.Y. Acad. Sci., 1980, vol. 343, pp. 391–404. Article PubMed CAS Google Scholar Weintraub, B.D., Stannard, B.S., Linnekin, D., and Marshall, M., Relationship of glycosylation to de novo thyroid-stimulating hormone biosynthesis and secretion…
Enhancement and inactivation effect of CRISPR/Cas12a via extending hairpin activators for detection of transcription factors
Li Q, Song ZL, Zhang YX, Zhu LN, Yang Q, Liu XF, Sun XF, Chen XX, Kong RM, Fan GC, Luo XL (2023) Synergistic Incorporation of two ssDNA activators enhances the trans-cleavage of CRISPR/Cas12a. Anal Chem 95:8879–8888 Article CAS PubMed Google Scholar Ma JY, Wang SY, Du YC, Wang DX,…
De novo variants underlying monogenic syndromes with intellectual disability in a neurodevelopmental cohort from India
Russell PSS, Nagaraj S, Vengadavaradan A, Russell S, Mammen PM, Shankar SR, et al. Prevalence of intellectual disability in India: a meta-analysis. World J Clin Pediatr. 2022;11:206–14. Article PubMed PubMed Central Google Scholar Winnepenninckx B, Rooms L, Kooy RF. Mental retardation: a review of the genetic causes. Br J Dev…
Progress of circRNA/lncRNA-miRNA-mRNA axis in atrial fibrillation [PeerJ]
Introduction The incidence and mortality rates of AF are continuously increasing, leading to serious complications such as heart failure and stroke (Fig. 1) (Sagris et al., 2021). The occurrence and development of AF involve different mechanisms and interactions (Kornej et al., 2020). AF often progresses from paroxysmal to persistent (Nattel…
Characterization of the Spectrum of Mitochondrial DNA Nucleotide Substitutions in Human Populations in High Altitude Environments
Burtscher, J., Mallet, R.T., Pialoux, V., et al., Adaptive responses to hypoxia and/or hyperoxia in humans, Antioxid. Redox Signal., 2022, vol. 37, pp. 887—912. doi.org/10.1089/ars.2021.0280 Article PubMed Google Scholar Chandel, N.S., McClintock, D.S., Feliciano, C.E., et al., Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a…
Probing the conformational changes of in vivo overexpressed cell cycle regulator 6S ncRNA
join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Probing the conformational changes of in vivo overexpressed cell cycle regulator 6S ncRNA Makraki, E. ; Miliara, S. ; Pagkalos, M. ; Kokkinidis, M. ; Mylonas, E. (Corresponding author)Extern*EMBL* ; Fadouloglou, V. E. (Corresponding author)Extern*EMBL* 2023Frontiers Lausanne This record in other databases: Please use a persistent id in citations: doi:10.3389/fmolb.2023.1219668 doi:10.3204/PUBDB-2023-07967 Abstract: The…
Characterization of runs of Homozygosity revealed genomic inbreeding and patterns of selection in indigenous sahiwal cattle
Almeida OAC, Moreira GCM, Rezende FM et al (2019) Identification of selection signatures involved in performance traits in a paternal broiler line. BMC Genomics 20:1–20. doi.org/10.1186/s12864-019-5811-1 Article Google Scholar Alshawi A, Essa A, Al-Bayatti S, Hanotte O (2019) Genome Analysis Reveals Genetic Admixture and Signature of Selection for Productivity and…
Effects of plant-based proteins and handling stress on intestinal mucus microbiota in rainbow trout
FAO. The State of World Fisheries and Aquaculture 2022: Towards Blue Transformation (FAO, 2022). Google Scholar Hua, K. et al. The future of aquatic protein: Implications for protein sources in aquaculture diets. One Earth 3, 316–329 (2019). Article Google Scholar Hardy, R. W. Utilization of plant proteins in fish diets:…
Assessment of genetic diversity, population structure and wolf-dog hybridisation in the Eastern Romanian Carpathian wolf population
Kershaw, F. et al. The Coalition for Conservation Genetics: Working across organizations to build capacity and achieve change in policy and practice. Conserv. Sci. Pract. 4, e12635 (2022). Article Google Scholar Waits, L. P. & Paetkau, D. Noninvasive genetic sampling tools for wildlife biologists: a review of applications and recommendations…
Plasma cell-free DNA 5-hydroxymethylcytosine and whole-genome sequencing signatures for early detection of esophageal cancer
Waters JK, Reznik SI. Update on management of squamous cell esophageal cancer. Curr Oncol Rep. 2022;24:375–85. Article PubMed Google Scholar Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185…
Perception of genomic newborn screening among peripartum mothers
Therrell BL, Padilla CD, Loeber JG, Kneisser I, Saadallah A, Borrajo GJC, et al. Current status of newborn screening worldwide: 2015. Semin Perinatol. 2015;39:171–87. Article PubMed Google Scholar Battelino T, Kržišnik C, Pavlin K. Early detection and follow-up of children with phenylketonuria in Slovenia. Zdr Vestn. 1994;63:25–8. Google Scholar Lampret…
Validation of Oxford nanopore sequencing for improved New World Leishmania species identification via analysis of 70-kDA heat shock protein | Parasites & Vectors
Akhoundi M, Downing T, Votypka J, Kuhls K, Lukes J, Cannet A, et al. Leishmania infections: molecular targets and diagnosis. Mol Aspects Med. 2017;57:1–29. Article PubMed Google Scholar Akhoundi M, Kuhls K, Cannet A, Votypka J, Marty P, Delaunay P, et al. A historical overview of the classification, evolution, and…
List of Artificial Intelligence Models for Medical Landscape (2023)
Given the number of advancements artificial intelligence (AI) has made this year itself, it’s no surprise that it has been a significant point of discussion throughout 2023. AI now finds its use case in almost every realm, and one of its exciting and useful applications is in healthcare and medicine….
Gut Microbiome and Bifidobacterium Research in Zimbabwe
Introduction The Infant Gut Microbiome Untangling what constitutes a healthy gut microbiome is timely, particularly in low- and middle-income (LMIC) settings where problems of infant nutrition, chronic diarrhea, and failure to thrive are high priority.1,2 Studying the infant gut microbiome is also crucial as many of the events capable of…
Phylogenomic analysis of 343 Xanthomonas citri pv. citri strains unravels introduction history and dispersal paths
. 2023 Dec 15;19(12):e1011876. doi: 10.1371/journal.ppat.1011876. Online ahead of print. Jin Xu 1 , Yanan Zhang 1 , Jinyun Li 1 , Doron Teper 1 , Xiaoan Sun 2 , Debra Jones 2 , Yayu Wang 3 , Jin Tao 4 , Erica M Goss 5 6 , Jeffrey B Jones 5 , Nian Wang 1 Affiliations Expand Affiliations…
Elevating intracellular action potential recording in cardiomyocytes: A precision-enhanced and biosafe single-pulse electroporation system
. 2023 Nov 24:246:115860. doi: 10.1016/j.bios.2023.115860. Online ahead of print. Affiliations Expand Affiliations 1 Department of Chemistry, Zhejiang-Israel Joint Laboratory of Self-Assembling Functional Materials, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 310058, China. 2 State Key Laboratory of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of…
First complete mitogenome of Massarineae and its contribution to phylogenetic implications in Pleosporales
Crous, P. W. et al. Fungal Planet description sheets: 214–280. Persoonia 32, 184–306 (2014). Article PubMed PubMed Central Google Scholar Zhang, Y. et al. Multi-locus phylogeny of Pleosporales: A taxonomic, ecological and evolutionary re-evaluation. Stud. Mycol. 64, 85–105 (2009). Article PubMed PubMed Central Google Scholar Schoch, C. L. et al….
Metagenome analyses identify human endogenous retrovirus-K113 (HML-2) subtype in glioblastoma
. 2023 Dec 15;133(24):e173959. doi: 10.1172/JCI173959. Item in Clipboard Amanda Macamo et al. J Clin Invest. 2023. Show details Display options Display options Format AbstractPubMedPMID . 2023 Dec 15;133(24):e173959. doi: 10.1172/JCI173959. Item in Clipboard Cite Display options Display options Format AbstractPubMedPMID No abstract available Keywords: Brain cancer; Oncology; Virology. PubMed Disclaimer…
Metagenome analyses identify human endogenous retrovirus-K113 (HML-2) subtype in glioblastoma. Reply
. 2023 Dec 15;133(24):e176406. doi: 10.1172/JCI176406. Affiliations Expand Affiliations 1 Miller School of Medicine, Department of Neurological Surgery, University of Miami, Coral Gables, Florida, USA. 2 National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland, USA. Item in Clipboard Vaidya Govindarajan et al. J Clin Invest. 2023. Show details Display…
A Database of RNA Modifications
Modomics – A Database of RNA Modifications RsmA from Thermus thermophilus – protein summary. ID Card: Full name: Ribosomal RNA small subunit methyltransferase A Synonym: KsgA, TTHA0083 GI: 55980052 COG: COG0030 UniProt: Q5SM60 Structures: | 3FUT | 3FUU | 3FUW | 3FUV | 3FUX | Enzyme type: methyltransferase Position of…
TWAS revealed significant causal loci for milk production and its composition in Murrah buffaloes
Cao, C. et al. Power analysis of transcriptome-wide association study: Implications for practical protocol choice. PLoS Genet. 17(2), e1009405 (2021). Article CAS PubMed PubMed Central Google Scholar De Camargo, G. M. F. et al. Prospecting major genes in dairy buffaloes. BMC Genomics 16, 1–14 (2015). Article Google Scholar El-Halawany, N….
Surgical Management and Long-Term Outcomes of BIA-ALCL: A Multidisciplinary Approach
Kaartinen I, Sunela K, Alanko J, Hukkinen K, Karjalainen-Lindsberg ML, Svarvar C. Breast implant-associated anaplastic large cell lymphoma—from diagnosis to treatment. Eur J Surg Oncol. 2017;43(8):1385–92. doi.org/10.1016/j.ejso.2017.05.021. Article CAS PubMed Google Scholar Leberfinger AN, Behar BJ, Williams NC, et al. Breast implant-associated anaplastic large cell lymphoma: a systematic review. JAMA…
Outcomes of allogeneic hematopoietic stem cell transplantation for relapsed or refractory diffuse large B-cell lymphoma
Coiffier B, Lepage E, Briere J, Herbrecht R, Tilly H, Bouabdallah R, et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med. 2002;346:235–242. Article CAS PubMed Google Scholar Philip T, Guglielmi C, Hagenbeek A, Somers R, Van der Lelie…
Arsenic is a potent co-mutagen of ultraviolet light
Barnes, J. L., Zubair, M., John, K., Poirier, M. C. & Martin, F. L. Carcinogens and DNA damage. Biochem. Soc. Trans. 46, 1213–1224 (2018). Article CAS PubMed PubMed Central Google Scholar Ames, B. N., Durston, W. E., Yamasaki, E. & Lee, F. D. Carcinogens are mutagens: a simple test system…
First report of cutaneous leishmaniasis caused by Leishmania donovani in Ethiopia | Parasites & Vectors
Alvar J, Vélez ID, Bern C, Herrero M, Desjeux P, Cano J, et al. Leishmaniasis worldwide and global estimates of its incidence. PLoS ONE. 2012. doi.org/10.1371/journal.pone.0035671. Article PubMed PubMed Central Google Scholar Gadisa E, Tsegaw T, Abera A, Elnaiem DE, Den Boer M, Aseffa A, et al. Eco-epidemiology of visceral…
GWAS Catalog
Available data: Associations Studies Full summary statistics LocusZoom Download Associations Download files Include background traits data Associations Variant and risk allele P-value P-value annotation RAF OR Beta CI Mapped gene Reported trait Trait(s) Background trait(s) Study accession First Author PubMed ID Location Variant and risk allele P-value P-value annotation RAF…
Diversity and dissemination of viruses in pathogenic protozoa
Wang, A. L. & Wang, C. C. Viruses of the protozoa. Annu. Rev. Microbiol. 45, 251–263 (1991). Article CAS PubMed Google Scholar Banik, G., Stark, D., Rashid, H. & Ellis, J. Recent advances in molecular biology of parasitic viruses. Infect. Disord. – Drug Targets 14, 155–167 (2015). Article Google Scholar …
PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis | Cancer Cell International
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49. doi.org/10.3322/caac.21660. Article PubMed Google Scholar Hu G, Chong RA, Yang Q, Wei Y, Blanco…
Chromosome-level genome assembly of the Stoliczka’s Asian trident bat (Aselliscus stoliczkanus)
Dobson, G. E. On a new genus and species of Rhinolophidae, with description of a new species of Vesperus, and notes on some other species of insectivorous bats from Persia. J. Asiat. Soc. Bengal. 40, 455–461 (1871). Google Scholar Bates, P., Bumrungsri, S., Francis, C., Csorba, G. & Furey, N….
Maternal dominance contributes to subgenome differentiation in allopolyploid fishes
Otto, S. P. & Whitton, J. Polyploid incidence and evolution. Annu. Rev. Genet. 34, 401–437 (2000). Article CAS PubMed Google Scholar Van de Peer, Y., Maere, S. & Meyer, A. The evolutionary significance of ancient genome duplications. Nat. Rev. Genet. 10, 725–732 (2009). Article PubMed Google Scholar Comai, L. The…
Spatial Localization of Eubacterial 16S rRNA in Early Pregnancy Placenta and Decidua
. 2023 Dec 14:10935266231217629. doi: 10.1177/10935266231217629. Online ahead of print. Affiliations Expand Affiliation 1 Department of Pathology, British Columbia Children’s and Women’s Hospitals, Vancouver, BC, Canada. Item in Clipboard Cornelia Thoeni et al. Pediatr Dev Pathol. 2023. Show details Display options Display options Format AbstractPubMedPMID . 2023 Dec 14:10935266231217629. doi: 10.1177/10935266231217629….
CTCF deletion alters the pluripotency and DNA methylation profile of human iPSCs
. 2023 Nov 30:11:1302448. doi: 10.3389/fcell.2023.1302448. eCollection 2023. Affiliations Expand Affiliations 1 Institute for Stem Cell Biology, RWTH Aachen University Medical School, Aachen, Germany. 2 Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany. Item in Clipboard Deepika Puri et al. Front Cell Dev Biol. 2023. Show details Display…
SOCS3 inhibiting JAK-STAT pathway enhances oncolytic adenovirus efficacy by potentiating viral replication and T-cell activation
Kaufman HL, Kohlhapp FJ, Zloza A. Oncolytic viruses: a new class of immunotherapy drugs. Nat Rev Drug Discov. 2015;14:642–62. Article CAS PubMed PubMed Central Google Scholar Kessler T, Wick W. Oncolytic virotherapy: potentially a game-changing tumor treatment. Cancer Cell. 2021;39:753–5. Article CAS PubMed Google Scholar Koch J, Schober SJ, Hindupur…
Identification of Differentially Expressed Genes in Human Colorectal Cancer Using RNASeq Data Validated on the Molecular Level with Real-Time PCR
Allam RM, Al-Abd AM, Khedr A, Sharaf OA, Nofal SM, Khalifa AE, Mosli HA, Abdel-Naim AB (2018) Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells. Toxicol Lett 291:77–85 Article CAS PubMed Google Scholar Andrews S et al (2010) FastQC: a quality control tool…
File:FAM86B1 540px.gif – Wikipedia
Summary DescriptionFAM86B1 540px.gif English: Protein structure of human FAM86B1 isoform 1 predicted by AlphaFold. Colored by secondary structure, with alpha helices in red and beta strands in yellow. The SKL2 peroxisomal targeting signal is shown in green. Remaining coils are blue. gif shows FAM86B1 slowly spinning, so that the full…
Tax4Fun2 package are not found and github repository is not maintained anymore
Installation: Tax4Fun2 package are not found and github repository is not maintained anymore 5 Hi everyone! I have tried to find the R package Tax4Fun2 from the paper (pubmed.ncbi.nlm.nih.gov/33902725/) . This R package lets analizes the microbiome in an easy way to predict functional profiles from metagenomic 16S rRNA data….
Tree size diversity is the major driver of aboveground carbon storage in dryland agroforestry parklands
Albrecht, A. & Kandji, S. T. Carbon sequestration in tropical agroforestry systems. Agric. Ecosyst. Environ. 1–3, 15–27 (2003). Article Google Scholar Nair, P. K. R. Agroforestry systems and environmental quality: Introduction. J. Environ. Qual. 40, 784–790 (2011). Article CAS PubMed Google Scholar Schroth, G. & McNeely, J. A. Biodiversity conservation,…
Viruses under the Antarctic Ice Shelf are active and potentially involved in global nutrient cycles
Rignot, E., Jacobs, S., Mouginot, J. & Scheuchl, B. Ice-shelf melting around antarctica. Science (80-) 341, 266–270 (2013). Article ADS CAS Google Scholar Wadham, J. L. et al. Ice sheets matter for the global carbon cycle. Nat. Commun. 10, 1–17 (2019). Google Scholar Adusumilli, S., Fricker, H. A., Medley, B.,…
New study highlights the need for advanced pneumococcal vaccines in the wake of pre-COVID data
In a recent study published in the Lancet Regional Health, researchers describe serotype distribution in hospitalized adults diagnosed with pneumococcal community-acquired pneumonia (CAP) in the United Kingdom (UK) in the two years before the onset of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic using a 24-valent serotype-specific urinary antigen…
Freshers Job Bsc Msc Biotech, Bioinformatics at Clarivate
–Must See– Freshers Job Bsc Msc – Freshers Clarivate Job – Associate Content Editor Job Number: JREQ124259 City, ST: Chennai, TN Associate Content Editor – GENESEQ We are seeking an Associate Content Editor to join our GENESEQ process in Hyderabad/Chennai. This presents a fantastic opportunity to contribute to the GENESEQ…
Importance of a detailed anomaly scan after a cfDNA test indicating fetal trisomy 21, 18 or 13
Kagan KO, Sonek J, Kozlowski P (2022) Antenatal screening for chromosomal abnormalities. Arch Gynecol Obstet 305(4):825–835 Article CAS PubMed PubMed Central Google Scholar Rose NC, Barrie ES, Malinowski J, Jenkins GP, McClain MR, LaGrave D et al (2022) Systematic evidence-based review: the application of noninvasive prenatal screening using cell-free DNA…
Whole mitochondrial and chloroplast genome sequencing of Tunisian date palm cultivars: diversity and evolutionary relationships | BMC Genomics
Johnson DV, Al-Khayri JM, Jain SM. Introduction: Date Production Status and Prospects in Africa and the Americas. In: Al-Khayri J, Jain S, Johnson D, editors. Date Palm Genetic Resources and Utilization: Volume 1: Africa and the Americas. Springer Netherlands, Dordrecht; 2015. p. 1–18. doi.org/10.1007/978-94-017-9694-1_1 Gros-Balthazard M, Hazzouri KM, Flowers JM. Genomic…
cGAS-STING signalling regulates microglial chemotaxis in genome instability
doi: 10.1093/nar/gkad1184. Online ahead of print. Affiliations Expand Affiliations 1 Department of Biochemistry, University of Cambridge, Cambridge, UK. 2 Neuroscience, R&D BioPharmaceuticals, AstraZeneca, Cambridge, UK. 3 Translational Genomics, Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Mölndal, Gothenburg, Sweden. 4 Department of Data Sciences & Quantitative Biology, AstraZeneca, Cambridge, UK. Item…
Response of Arctic benthic foraminiferal traits to past environmental changes
Hersbach, H. et al. ERA5 hourly data on single levels from 1940 to present. Copernicus Climate Change Service (C3S) Climate Data Store (CDS). In Copernicus Climate Change Service (C3S) Climate Data Store (CDS) (2023). doi.org/10.24381/cds.adbb2d47. Constable, A. J. et al. Cross-chapter paper 6: Polar regions. In Climate Change 2022: Impacts,…
An integrated individual-level trait-based phytoplankton dataset from transitional waters
McGill, B. J., Enquist, B. J., Weiher, E. & Westoby, M. Rebuilding community ecology from functional traits. Trends Ecol. Evol. 21, 178–185 (2006). Article PubMed Google Scholar Diaz, S. et al. The global spectrum of plant form and function: enhanced species-level trait dataset. Sci. Data 9, 755 (2022). Article PubMed …
Molecular Techniques | SpringerLink
Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, Hall KP, Evers DJ, Barnes CL, Bignell HR et al (2008) Accurate whole human genome sequencing using reversible terminator chemistry. Nature 456:53–59 CrossRef CAS PubMed PubMed Central Google Scholar Büyükköroğlu G, Dora DD, Özdemir F, Hızel C (2018)…
Heavy-chain antibody targeting of CD38 NAD+ hydrolase ectoenzyme to prevent fibrosis in multiple organs
Asano, Y. & Varga, J. Rationally-based therapeutic disease modification in systemic sclerosis: Novel strategies. Semin. Cell Dev. Biol. 101, 148–160. doi.org/10.1016/j.semcdb.2019.12.007 (2019). Article Google Scholar Allanore, Y. et al. Systemic sclerosis. Nat. Rev. Dis. Prim. 1, 15002. doi.org/10.1038/nrdp.2015.2 (2015). Article PubMed Google Scholar Varga, J. & Abraham, D. Systemic sclerosis:…
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
Khan, S. et al. Role of recombinant DNA technology to improve life. Int. J. Genomics Proteomics 2016, 2405954 (2016). Google Scholar Spolski, R., Li, P. & Leonard, W. J. Biology and regulation of IL-2: from molecular mechanisms to human therapy. Nat. Rev. Immunol. 18, 648–659 (2018). Article CAS PubMed Google…
The Protective Mechanism of TFAM on Mitochondrial DNA and its Role in Neurodegenerative Diseases
Annesley SJ, Fisher PR (2019) Mitochondria in health and disease. Cells 8(7). doi.org/10.3390/cells8070680 Cannino G, Ferruggia E, Luparello C, Rinaldi AM (2009) Cadmium and mitochondria. Mitochondrion 9(6):377–384. doi.org/10.1016/j.mito.2009.08.009 Article CAS PubMed Google Scholar Bonora M, Missiroli S, Perrone M, Fiorica F, Pinton P, Giorgi C (2021) Mitochondrial control of genomic…
Characterizing viral species in mosquitoes (Culicidae) in the Colombian Orinoco: insights from a preliminary metagenomic study
Kraemer, M. U. et al. The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus. Elife 4, e08347. doi.org/10.7554/eLife.08347 (2015). Article PubMed PubMed Central Google Scholar Bhatt, S. et al. The global distribution and burden of dengue. Nature 496, 504–507. doi.org/10.1038/nature12060 (2013). Article ADS CAS PubMed PubMed Central …
A laboratory ice machine as a cold oligotrophic artificial microbial niche for biodiscovery
Flemming, H.-C. & Wuertz, S. Bacteria and archaea on earth and their abundance in biofilms. Nat. Rev. Microbiol. 17, 247–260 (2019). Article CAS PubMed Google Scholar Flemming, H.-C., Neu, T. R. & Wozniak, D. J. The EPS matrix: The “house of biofilm cells”. J. Bacteriol. 189, 7945–7947 (2007). Article CAS …
Phyloecology of nitrate ammonifiers and their importance relative to denitrifiers in global terrestrial biomes
Steffen, W. et al. Planetary boundaries: guiding human development on a changing planet. Science 347, 1259855 (2015). Article PubMed Google Scholar Kanter, D. R. et al. Nitrogen pollution policy beyond the farm. Nat. Food 1, 27–32 (2020). Article ADS Google Scholar Tian, H. et al. A comprehensive quantification of global…
Generating a New sgRNA Vector, pGL3-U6-sgRNA-PGK-mRFP-T2A-PuroR, to Improve Base Editing
doi: 10.32371/jger/246146. Epub 2022 Dec 17. Affiliations Expand Affiliation 1 Center for Molecular and Cellular Biosciences, School of Biological, Environmental, and Earth Sciences, University of Southern Mississippi, Hattiesburg, Mississippi 39406, United States of America. Free PMC article Item in Clipboard Tolulope E Ayo et al. J Genome Ed Regul. 2022. Free…
Analysis of geometric morphometrics and molecular phylogeny for Anopheles species in the Republic of Korea
World Health Organization (WHO). WHO malaria report. 2022 www.who.int/publications/i/item/9789240064898 (2022). Savi, M. K. An overview of malaria transmission mechanisms, control, and modeling. Med. Sci. 11, 3 (2023). Google Scholar Bahk, Y. Y. et al. Epidemiological characteristics of re-emerging vivax malaria in the Republic of Korea (1993–2017). Korean J. Parasitol. 56,…
Construction of a risk stratification model integrating ctDNA to predict response and survival in neoadjuvant-treated breast cancer | BMC Medicine
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49. Article PubMed Google Scholar Giaquinto AN, Sung H, Miller KD, Kramer JL, Newman LA,…
Insight into chloroplast genome structural variation of the Mongolian endemic species Adonis mongolica (Ranunculaceae) in the Adonideae tribe
Wang, W. T. Revision of Adonis (Ranunculaceae). Bull. Bot. Res. 14, 1–31 (1994). Google Scholar Gao, T. et al. Evaluating the feasibility of using candidate DNA Barcodes in discriminating species of the large Asteraceae family. BMC Evol. Biol. 10, 324 (2016). Article Google Scholar Conti, F. et al. Adonis fucensis…
Panel-based RNA fusion sequencing improves diagnostics of pediatric acute myeloid leukemia
Rasche M, Zimmermann M, Borschel L, Bourquin J, Dworzak M, Klingebiel T, et al. Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012. Leukemia. 2018;32:2167–77. Article PubMed PubMed Central Google Scholar Manola KN. Cytogenetics of pediatric acute…
Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders | BMC Medicine
Lichtenstein P, Yip BH, Bjork C, Pawitan Y, Cannon TD, Sullivan PF, Hultman CM. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet. 2009;373(9659):234–9. Article PubMed Google Scholar Maurano MT, Humbert R, Rynes E, Thurman RE, Haugen E, Wang H, Reynolds AP, Sandstrom R,…
RPTOR mutation: a novel predictor of efficacious immunotherapy in melanoma
Li Z, Gao Y, Cao Y et al (2023) Extracellular RNA in Melanoma: advances, challenges, and opportunities. Front Cell Dev Biol 11:1141543. doi.org/10.3389/fcell.2023.1141543 Article PubMed PubMed Central Google Scholar Hamid O, Cowey CL, Offner M, Faries M, Carvajal RD (2019) Efficacy, Safety, and tolerability of approved combination BRAF and MEK…
Wide bovine tick-borne pathogen spectrum: Predominancy of Theileria annulata and the first molecular detection of Ehrlichia minasensis in Turkey
Agina OA, Shaari MS, Isa NMM, Ajat M, Zamri-Saad M, Hamzah H (2020) Clinical pathology, immunopathology and advanced vaccine technology in bovine theileriosis: A review. Pathogens 9:697. doi.org/10.3390/pathogens9090697 Article PubMed PubMed Central CAS Google Scholar Aktas M (2014) A survey of ixodid tick species and molecular identification of tick-borne pathogens….
Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity
Huang, Q., Zeng, J. & Yan, J. COVID-19 mRNA vaccines. J. Genet. Genomics 48, 107–114 (2021). Article CAS PubMed PubMed Central Google Scholar Huang, S., Zhu, Y., Zhang, L. & Zhang, Z. Recent advances in delivery systems for genetic and other novel vaccines. Adv. Mater. 34, e2107946 (2022). Article PubMed …
ggplot2 – How to get the label positioned correctly in R?
You can make the same plot with a fixed x axis as follows: library(ggplot2) library(ggtext) data.frame(word = rep(c(‘<i>Criptosporidium<br>parvum</i>’, ‘CSPV1’, ‘CSPV1 TLR3’), each = 2), n= c(69300,4858, 145, 6, 11, 0), Database = rep(c(‘Google Scholar’, ‘PubMed’), 3), check.names = FALSE) |> ggplot(aes(word, n)) + geom_col(aes(fill = Database), position = ‘dodge’) +…
Genetic architecture of cardiac dynamic flow volumes
Virani, S. S. et al. Heart disease and stroke statistics-2021 update: a report from the American Heart Association. Circulation 143, e254–e743 (2021). Article PubMed Google Scholar Nauffal, V. et al. Genetics of myocardial interstitial fibrosis in the human heart and association with disease. Nat. Genet. 55, 777–786 (2023). Article CAS …
DLBCL arising from indolent lymphomas: How are they different?
. 2023 Nov 23:S0037-1963(23)00089-6. doi: 10.1053/j.seminhematol.2023.11.002. Online ahead of print. Affiliations Expand Affiliations 1 Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; Harvard Medical School, Boston, MA; Broad Institute of MIT and Harvard, Cambridge, MA. 2 Aix-Marseille University, CNRS, INSERM, Centre d’Immunologie de Marseille-Luminy, Marseille, France. 3 Centre for…
AstraZeneca Bioinformatics Job – Bioinformatics Consultant Post
“Unlock Your Potential: Join AstraZeneca as a Bioinformatics Consultant and Revolutionize Drug Discovery!” –Must See– AstraZeneca Bioinformatics Job Job Post: Consultant – Bio Informatician At AstraZeneca, our mission is to improve the quality of healthcare and make a positive impact on the lives of millions of patients. We are seeking…
A CNN based m5c RNA methylation predictor
Hammad, M. et al. A novel end-to-end deep learning approach for cancer detection based on microscopic medical images. Biocybern. Biomed. Eng. 42(3), 737–748 (2022). Article Google Scholar Hammad, M. et al. Efficient multimodal deep-learning-based covid-19 diagnostic system for noisy and corrupted images. J. King Saud Univ.-Sci. 34(3), 101898 (2022). Article …
Uncovering myocardial infarction genetic signatures using GWAS exploration in Saudi and European cohorts
Benjamin, E. J. et al. Heart disease and stroke statistics-2019 update: A report from the American Heart Association. Circulation 139, e56–e528 (2019). Article PubMed Google Scholar Yusuf, S. et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet 364,…
A minimally invasive, field-applicable CRISPR/Cas biosensor to aid in the detection of Pseudogymnoascus destructans, the causative fungal agent of white-nose syndrome in bats
doi: 10.1111/1755-0998.13902. Online ahead of print. Affiliations Expand Affiliations 1 U.S. Geological Survey, Wetland and Aquatic Research Center, Gainesville, Florida, USA. 2 Washington Department of Fish and Wildlife, Olympia, Washington, USA. 3 Cherokee Nation System Solutions, Contractor to the U.S. Geological Survey, Gainesville, Florida, USA. Item in Clipboard Adam A…
In situ metagenomics: A platform for rapid sequencing and analysis of metagenomes in less than one day
doi: 10.1111/1755-0998.13909. Online ahead of print. Affiliations Expand Affiliations 1 Microbiome Analysis Laboratory, Systems Biology Department, CNB-CSIC, Madrid, Spain. 2 Departamento de Ecoloxía e Bioloxía Animal, Centro de Investigación Mariña, Universidade de Vigo, Vigo, Spain. 3 Department of Biogeochemistry and Microbial Ecology, National Museum of Natural Sciences (MNCN-CSIC), Madrid, Spain….
Protective Effects of Bombyx batryticatus Protein-Rich Extract Against Cisplatin-Induced Nephrotoxicity in HEK293 Cells and a Mouse Model
. 2023 Dec;26(12):927-938. doi: 10.1089/jmf.2023.K.0182. Affiliations Expand Affiliations 1 Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Korea. 2 Department of Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul, Korea. Item in Clipboard Jeong Moo Han et al. J Med Food. 2023 Dec. Show details Display options…
Haplotype-resolved genome of heterozygous African cassava cultivar TMEB117 (Manihot esculenta)
Wang, P. et al. The genome evolution and domestication of tropical fruit mango. Genome Biol 21 (2020). Tang, C. et al. The rubber tree genome reveals new insights into rubber production and species adaptation. Nat Plants 2 (2016). Bredeson, J. V. et al. Sequencing wild and cultivated cassava and related…
SOCS2 inhibits hepatoblastoma metastasis via downregulation of the JAK2/STAT5 signal pathway
Weighted gene co-expression network analysis GSE131329 has comprehensive clinical data, and WGCNA was carried out with this expression profile. WGCNA is a systems biology method for characterizing gene association patterns between different samples, used to identify highly synergistic sets of genes and to screen for candidate biomarker genes or therapeutic…
Glabridin improves autoimmune disease in Trex1-deficient mice by reducing type I interferon production | Molecular Medicine
Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem. 2009;55:611–22. Article CAS PubMed Google Scholar Chen Q, Sun L, Chen ZJ….
Addgene: ph7SK-CDX2-gRNA
These plasmids were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications. For your Materials & Methods section: ph7SK-CDX2-gRNA was a gift from Mark Denham (Addgene plasmid # 192513…
Freshwater Viral Metagenome Analyses Targeting dsDNA Viruses
doi: 10.1007/978-1-0716-3515-5_3. Affiliations Expand Affiliations 1 Division of Environmental Materials, Honam National Institute of Biological Resources, Mokpo, Republic of Korea. 2 Department of Biological Sciences and Bioengineering, Inha University, Incheon, Republic of Korea. chojc@inha.ac.kr. Item in Clipboard Kira Moon et al. Methods Mol Biol. 2024. Show details Display options Display options…
Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes | Cardiovascular Diabetology
American Diabetes A. Economic costs of Diabetes in the U.S. in 2017. Diabetes Care. 2018;41(5):917–28. Article Google Scholar Linssen PBC, Veugen MGJ, Henry RMA, van der Kallen CJH, Kroon AA, Schram MT, Brunner-La Rocca HP, Stehouwer CDA. Associations of (pre)Diabetes with right ventricular and atrial structure and function: the Maastricht…
The MetaInvert soil invertebrate genome resource provides insights into below-ground biodiversity and evolution
FAO, ITPS, GSBI, CBD & EC. State of knowledge of soil biodiversity – Status, challenges and potentialities, Report 2020. (FAO). doi.org/10.4060/cb1928en. 2020. Potapov, A. M. et al. Feeding habits and multifunctional classification of soil-associated consumers from protists to vertebrates. Biol. Rev. 97, 1057–1117 (2022). Article PubMed Google Scholar García-Palacios, P.,…
From Metagenomics to Ecogenomics: NGS-Based Approaches for Discovery of New Circular DNA Single-Stranded Viral Species
doi: 10.1007/978-1-0716-3515-5_7. Affiliations Expand Affiliations 1 Departamento de Biotecnología Agrícola, Instituto Politécnico Nacional, CIIDIR Unidad Sinaloa, Guasave, Sinaloa, Mexico. 2 Department of Plant Biochemistry, Center for Plant Molecular Biology (ZMBP), Eberhard Karls University, Tübingen, Germany. 3 Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora”, Universidad de Málaga-Consejo Superior de Investigaciones…
Metagenomics reveals effects of fluctuating water conditions on functional pathways in plant litter microbial community
Keller, J. K. Wetlands and the global carbon cycle: what might the simulated past tell us about the future?. New Phytol. 192, 789–792 (2011). Article CAS PubMed Google Scholar Dolinar, N., Rudolf, M., Šraj, N. & Gaberščik, A. Environmental changes affect ecosystem services of the intermittent Lake Cerknica. Ecol. Complex….
Serum IgE anti-dsDNA autoantibodies in patients with proliferative lupus nephritis are associated with tubulointerstitial inflammation
doi: 10.1080/0886022X.2023.2273981. Epub 2023 Dec 7. Affiliations Expand Affiliations 1 Renal Division, Department of Medicine, Peking University First Hospital, Beijing, PR China. 2 Institute of Nephrology, Peking University, Beijing, PR China. 3 Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, PR China. 4 Key Laboratory of Chronic…