Tag: PubMed

Novel gene rearrangement in the mitochondrial genome of Anastatus fulloi (Hymenoptera Chalcidoidea) and phylogenetic implications for Chalcidoidea

1. Osellame, L. D., Blacker, T. S. & Duchen, M. R. Cellular and molecular mechanisms of mitochondrial function. Best Pract. Res. Clin. Endocrinol. Metab. 26, 711–723 (2012). CAS  PubMed  PubMed Central  Google Scholar  2. Bernt, M., Braband, A., Schierwater, B. & Stadler, P. F. Genetic aspects of mitochondrial genome evolution….

Continue Reading Novel gene rearrangement in the mitochondrial genome of Anastatus fulloi (Hymenoptera Chalcidoidea) and phylogenetic implications for Chalcidoidea

Comprehensive summary of mitochondrial DNA alterations in the postmortem human brain: A systematic review

Summary Background Mitochondrial DNA (mtDNA) encodes 37 genes necessary for synthesizing 13 essential subunits of the oxidative phosphorylation system. mtDNA alterations are known to cause mitochondrial disease (MitD), a clinically heterogeneous group of disorders that often present with neuropsychiatric symptoms. Understanding the nature and frequency of mtDNA alterations in health…

Continue Reading Comprehensive summary of mitochondrial DNA alterations in the postmortem human brain: A systematic review

Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose-response study designs

doi: 10.1093/nar/gkac019. Online ahead of print. Affiliations Expand Affiliations 1 Department of Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI, USA. 2 Institute for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA. 3 Department of Statistics and Probability, Michigan State University, East Lansing, MI 48824, USA….

Continue Reading Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose-response study designs

Loncastuximab tesirine: an effective therapy for relapsed or refractory diffuse large B-cell lymphoma

Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of Non-Hodgkin’s lymphoma in the United States, with approximately 40% of first-line DLBCL chemoimmunotherapy attempts failing. The FDA approved a new type of antibody-drug conjugate (ADC), Zynlonta (loncastuximab tesirine), once called ADCT-402, on April 23, 2021, for relapsed or…

Continue Reading Loncastuximab tesirine: an effective therapy for relapsed or refractory diffuse large B-cell lymphoma

Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits

1. Jansen, I. E. et al. Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk. Nat. Genet. 51, 404–413 (2019). CAS  PubMed  PubMed Central  Google Scholar  2. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511, 421–427 (2014). PubMed…

Continue Reading Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits

Valine feeding reduces ammonia production through rearrangement of metabolic fluxes in central carbon metabolism of CHO cells

Aghamohseni H, Ohadi K, Spearman M, Krahn N, Moo-Young M, Scharer JM, Butler M, Budman HM (2014) Effects of nutrient levels and average culture pH on the glycosylation pattern of camelid-humanized monoclonal antibody. J Biotechnol 186:98–109. doi.org/10.1016/j.jbiotec.2014.05.024 CAS  Article  PubMed  Google Scholar  Altamirano C, Illanes A, Casablancas A, Gámez X,…

Continue Reading Valine feeding reduces ammonia production through rearrangement of metabolic fluxes in central carbon metabolism of CHO cells

Establishment of serum-free adapted Chinese hamster ovary cells with double knockout of GDP-mannose-4,6-dehydratase and GDP-fucose transporter

Aggarwal RS (2014) What’s fueling the biotech engine-2012 to 2013. Nat Biotechnol 32:32–39. doi.org/10.1038/nbt.2794 CAS  Article  PubMed  Google Scholar  Becker DJ, Lowe JB (2003) Fucose: biosynthesis and biological function in mammals. Glycobiology 13:41–53. doi.org/10.1093/glycob/cwg054 CAS  Article  Google Scholar  Chan KF, Shahreel W, Wan C et al (2016) Inactivation of GDP-fucose…

Continue Reading Establishment of serum-free adapted Chinese hamster ovary cells with double knockout of GDP-mannose-4,6-dehydratase and GDP-fucose transporter

Time-course RNASeq of Camponotus floridanus forager and nurse ant brains indicate links between plasticity in the biological clock and behavioral division of labor | BMC Genomics

1. Sharma VK. Adaptive significance of circadian clocks. Chronobiol Int. 2003;20(6):901–19. PubMed  Google Scholar  2. Paranjpe DA, Sharma VK. Evolution of temporal order in living organisms. J Circadian Rhythms. 2005;3(1):7. PubMed  PubMed Central  Google Scholar  3. Yerushalmi S, Green RM. Evidence for the adaptive significance of circadian rhythms. Ecol Lett….

Continue Reading Time-course RNASeq of Camponotus floridanus forager and nurse ant brains indicate links between plasticity in the biological clock and behavioral division of labor | BMC Genomics

Why is mtDNA maternal only? : explainlikeimfive

Mitochondria are kind of like an in-between of cell-organelles and bacteria that live in your cells. They are not made by your cells, but they replicate on their own (by splitting in two). For this, they use their own DNA (the mtDNA), not the DNA of your cells. When an…

Continue Reading Why is mtDNA maternal only? : explainlikeimfive

Long non-coding RNA MSTRG.81401 short hairpin RNA relieves diabetic neuropathic pain and behaviors of depression by inhibiting P2X4 receptor expression in type 2 diabetic rats

1. Nicodemus JM, Enriquez C, Marquez A, Anaya CJ, Jolivalt CG (2017) Murine model and mechanisms of treatment-induced painful diabetic neuropathy. Neuroscience 354:136–145. doi.org/10.1016/j.neuroscience.2017.04.036 CAS  Article  PubMed  Google Scholar  2. Morimoto SS, Kanellopoulos D, Manning KJ, Alexopoulos GS (2015) Diagnosis and treatment of depression and cognitive impairment in late life….

Continue Reading Long non-coding RNA MSTRG.81401 short hairpin RNA relieves diabetic neuropathic pain and behaviors of depression by inhibiting P2X4 receptor expression in type 2 diabetic rats

CRISPR-Cas12a ribonucleoprotein-mediated gene editing in the plant pathogenic fungus Magnaporthe oryzae

. 2021 Dec 24;3(1):101072. doi: 10.1016/j.xpro.2021.101072. eCollection 2022 Mar 18. Affiliations Expand Affiliation 1 Department of Plant Pathology, Kansas State University, Manhattan, KS, USA. Free PMC article Item in Clipboard Jun Huang et al. STAR Protoc. 2021. Free PMC article Show details Display options Display options Format AbstractPubMedPMID . 2021 Dec…

Continue Reading CRISPR-Cas12a ribonucleoprotein-mediated gene editing in the plant pathogenic fungus Magnaporthe oryzae

Estimating individual mtDNA haplotypes in mixed DNA samples by combining MinION and MiSeq

doi: 10.1007/s00414-021-02763-0. Online ahead of print. Affiliations Expand Affiliations 1 Department of Forensic Medicine, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan. hnakani@juntendo.ac.jp. 2 Department of Forensic Medicine, Saitama Medical University, 38 Morohongo, Moroyama, Saitama, 350-0495, Japan. 3 Department of Forensic Medicine, Juntendo University School of Medicine,…

Continue Reading Estimating individual mtDNA haplotypes in mixed DNA samples by combining MinION and MiSeq

Rare Diseases Are Focus of Latest Yale Journal of Biology and Medicine

The Yale Journal of Biology and Medicine’s (YJBM’s) December 2021 issue on rare disease has been published on PubMed Central. This focus issue features articles on just a few of the estimated 7,000 rare diseases people in the world experience. As we get closer to Rare Disease Day on February…

Continue Reading Rare Diseases Are Focus of Latest Yale Journal of Biology and Medicine

Decoding gene regulation in the fly brain

1. Li, H. et al. Classifying Drosophila olfactory projection neuron subtypes by single-cell RNA sequencing. Cell 171, 1206–1220 (2017). CAS  PubMed  PubMed Central  Google Scholar  2. Davie, K. et al. A single-cell transcriptome atlas of the aging Drosophila brain. Cell 174, 982–998 (2018). CAS  PubMed  PubMed Central  Google Scholar  3….

Continue Reading Decoding gene regulation in the fly brain

Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome

1. Wang, J. & Jia, H. Metagenome-wide association studies: fine-mining the microbiome. Nat. Rev. Microbiol. 14, 508–522 (2016). CAS  PubMed  Google Scholar  2. Moschen, A. R. et al. Lipocalin 2 protects from inflammation and tumorigenesis associated with gut microbiota alterations. Cell Host Microbe 19, 455–469 (2016). CAS  PubMed  Google Scholar …

Continue Reading Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome

UMass Chan Medical School hiring Research Lab Tech I – Neurogenerative Disease (CRISPR-Cas gene editing) in Worcester, Massachusetts, United States

OverviewGENERAL SUMMARY OF POSITION: We are seeking a Research Technician to work collaboratively on CRISPR-Cas gene editing of the Huntington’s Disease (HD) gene. HD is a devasting neurodegenerative disease that currently has no effective treatment. Our goal is to develop gene editing methods to inactivate or correct the disease-causing version…

Continue Reading UMass Chan Medical School hiring Research Lab Tech I – Neurogenerative Disease (CRISPR-Cas gene editing) in Worcester, Massachusetts, United States

Comparative de novo transcriptome analysis identifies salinity stress responsive genes and metabolic pathways in sugarcane and its wild relative Erianthus arundinaceus [Retzius] Jeswiet

1. Singh, A. et al. Phytochemical profile of sugarcane and its potential health aspects. Pharmacogn. Rev. 9, 45–54 (2015). CAS  PubMed  PubMed Central  Google Scholar  2. Eggleston, G. Positive aspects of cane sugar and sugar cane derived products in food and nutrition. J. Agric. Food Chem. 66, 4007–4012 (2018). CAS …

Continue Reading Comparative de novo transcriptome analysis identifies salinity stress responsive genes and metabolic pathways in sugarcane and its wild relative Erianthus arundinaceus [Retzius] Jeswiet

Publication A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA.

Your browser does not have JavaScript enabled. Some parts of this website may require JavaScript to function correctly First Author  Hashizume O Year  2015 Journal  PLoS One Volume  10 Issue  3 Pages  e0118561 PubMed ID  25738506 Mgi Jnum  J:233444 Mgi Id  MGI:5784636 Doi  10.1371/journal.pone.0118561 Citation  Hashizume O, et al. (2015)…

Continue Reading Publication A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA.

Comprehensive Analysis of mRNA, lncRNA, circRNA, and miRNA Expression Profiles and Their ceRNA Networks in the Longissimus Dorsi Muscle of Cattle-Yak and Yak

doi: 10.3389/fgene.2021.772557. eCollection 2021. Chun Huang  1 , Fei Ge  1 , Xiaoming Ma  1 , Rongfeng Dai  1 , Renqing Dingkao  2 , Zhuoma Zhaxi  3 , Getu Burenchao  3 , Pengjia Bao  1 , Xiaoyun Wu  1 , Xian Guo  1 , Min Chu  1 , Ping Yan  1 , Chunnian Liang  1 Affiliations Expand Affiliations 1 Key Laboratory of…

Continue Reading Comprehensive Analysis of mRNA, lncRNA, circRNA, and miRNA Expression Profiles and Their ceRNA Networks in the Longissimus Dorsi Muscle of Cattle-Yak and Yak

VCV000445854.7 Observations – ClinVar – NCBI

1 SCV000610624.1 Center for Pediatric Genomic Medicine,Children’s Mercy Hospital and Clinics Benign criteria provided,single submitter clinical testing not provided (not provided ) germline 1 SCV000700353.2 Eurofins NTD, LLC Uncertain significance criteria provided,single submitter clinical testing 1 not provided (unknown ) germline 1 Single Heterozygote www.egl-eurofins.com/emvclass/emvclass.php?approved_symbol=CYP21A2 mixed 1 SCV001137083.1 Mendelics Benign…

Continue Reading VCV000445854.7 Observations – ClinVar – NCBI

Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA

doi: 10.1093/nar/gkab1227. Online ahead of print. Regina Shebanova  1 , Natalia Nikitchina  1   2 , Nikita Shebanov  1 , Vladimir Mekler  3 , Konstantin Kuznedelov  3 , Egor Ulashchik  4 , Ruslan Vasilev  5   6 , Olga Sharko  4 , Vadim Shmanai  4 , Ivan Tarassov  2 , Konstantin Severinov  1   3   7 , Nina Entelis  2…

Continue Reading Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA

Nuclear Genome-Encoded Long Noncoding RNAs and Mitochondrial Damage in Diabetic Retinopathy

. 2021 Nov 23;10(12):3271. doi: 10.3390/cells10123271. Affiliations Expand Affiliations 1 Department of Ophthalmology, Visual & Anatomical Sciences, Wayne State University, Detroit, MI 48201, USA. 2 Kresge Eye Institute, 4717 St. Antoine, Detroit, MI 48201, USA. Item in Clipboard Ghulam Mohammad et al. Cells. 2021. Show details Display options Display options Format…

Continue Reading Nuclear Genome-Encoded Long Noncoding RNAs and Mitochondrial Damage in Diabetic Retinopathy

Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia

1. Marder, S. R. & Cannon, T. D. Schizophrenia. N. Engl. J. Med. 381, 1753–1761. doi.org/10.1056/NEJMra1808803 (2019). Article  PubMed  CAS  Google Scholar  2. Keshavan, M. S. et al. Neuroimaging in Schizophrenia. Neuroimaging Clin. N. Am. 30, 73–83. doi.org/10.1016/j.nic.2019.09.007 (2020). Article  PubMed  Google Scholar  3. McCutcheon, R. A., Reis Marques, T….

Continue Reading Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia

Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functions

1. Oh, J. et al. Biogeography and individuality shape function in the human skin metagenome. Nature 514, 59–64 (2014). 2. Byrd, A. L., Belkaid, Y. & Segre, J. A. The human skin microbiome. Nat. Rev. Microbiol. 16, 143–155 (2018). CAS  PubMed  Google Scholar  3. Oh, J. et al. Temporal stability…

Continue Reading Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functions

Valine tRNA levels and availability regulate complex I assembly in leukaemia

1. Rapino, F. et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature 558, 605–609 (2018). CAS  PubMed  Google Scholar  2. Goodarzi, H. et al. Modulated expression of specific tRNAs drives gene expression and cancer progression. Cell 165, 1416–1427 (2016). CAS  PubMed  PubMed Central  Google Scholar  3. Wolfe, A….

Continue Reading Valine tRNA levels and availability regulate complex I assembly in leukaemia

Zooplankton diversity monitoring strategy for the urban coastal region using metabarcoding analysis

1. Eyun, S. Phylogenomic analysis of Copepoda (Arthropoda, Crustacea) reveals unexpected similarities with earlier proposed morphological phylogenies. BMC Evol. Biol. 17, 23 (2017). PubMed  PubMed Central  Google Scholar  2. Eyun, S. et al. Evolutionary history of chemosensory-related gene families across the Arthropoda. Mol. Biol. Evol. 34, 1838–1862 (2017). CAS  PubMed …

Continue Reading Zooplankton diversity monitoring strategy for the urban coastal region using metabarcoding analysis

Gravity, AlphaFold and neural interfaces: a year of remarkable science

. 2021 Dec;600(7890):617-620. doi: 10.1038/d41586-021-03730-w. No authors listed Item in Clipboard No authors listed. Nature. 2021 Dec. Show details Display options Display options Format AbstractPubMedPMID . 2021 Dec;600(7890):617-620. doi: 10.1038/d41586-021-03730-w. Item in Clipboard Cite Display options Display options Format AbstractPubMedPMID No abstract available Keywords: Neuroscience; Physics; Solid Earth sciences; Structural…

Continue Reading Gravity, AlphaFold and neural interfaces: a year of remarkable science

A meta-analysis of XRCC1 single nucleotide polymorphism and susceptibility to gynecological malignancies

Background: Gynecological malignant tumor is a serious threat to women’s health, cervical cancer, endometrial cancer and ovarian cancer are the most common. The eponymous protein encoded by the XRCC1 (X-ray repair cross complementation 1) gene is an important functional protein in the process of single-stranded DNA damage. Non-synonymous mutations of…

Continue Reading A meta-analysis of XRCC1 single nucleotide polymorphism and susceptibility to gynecological malignancies

ddPCR allows 16S rRNA gene amplicon sequencing of very small DNA amounts from low-biomass samples | BMC Microbiology

1. Lane DJ, Pace B, Olsen GJ, Stahl DA, Sogin ML, Pace NR. Rapid determination of 16S ribosomal RNA sequences for phylogenetic analyses. Proc Natl Acad Sci U S A. 1985;82(20):6955–9. PubMed  PubMed Central  CAS  Google Scholar  2. Vos M, Quince C, Pijl AS, de Hollander M, Kowalchuk GA. A…

Continue Reading ddPCR allows 16S rRNA gene amplicon sequencing of very small DNA amounts from low-biomass samples | BMC Microbiology

Genome-wide identification of enhancers and transcription factors regulating the myogenic differentiation of bovine satellite cells | BMC Genomics

1. Yin H, Price F, Rudnicki MA. Satellite cells and the muscle stem cell niche. Physiol Rev. 2013;93(1):23–67. CAS  PubMed  PubMed Central  Google Scholar  2. Hoppeler H, Fluck M. Plasticity of skeletal muscle mitochondria: structure and function. Med Sci Sport Exer. 2003;35(1):95–104. CAS  Google Scholar  3. Astruc T: Carcass Composition,…

Continue Reading Genome-wide identification of enhancers and transcription factors regulating the myogenic differentiation of bovine satellite cells | BMC Genomics

Towards the biogeography of prokaryotic genes

1. Sunagawa, S. et al. Structure and function of the global ocean microbiome. Science 348, 1261359 (2015). PubMed  Google Scholar  2. Zou, Y. et al. 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses. Nat. Biotechnol. 37, 179–185 (2019). CAS  PubMed  PubMed Central  Google Scholar  3. Mohammad,…

Continue Reading Towards the biogeography of prokaryotic genes

Dynamic 23S rRNA modification ho5C2501 benefits Escherichia coli under oxidative stress

doi: 10.1093/nar/gkab1224. Online ahead of print. Affiliations Expand Affiliations 1 Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, 3012 Bern, Switzerland. 2 Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Bern, Switzerland. 3 Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck, University of Innsbruck, 6020 Innsbruck, Austria. 4 Rieveschl Laboratories…

Continue Reading Dynamic 23S rRNA modification ho5C2501 benefits Escherichia coli under oxidative stress

Human Cytomegalovirus UL138 Protein Inhibits the STING Pathway and Reduces Interferon Beta mRNA Accumulation during Lytic and Latent Infections

doi: 10.1128/mBio.02267-21. Online ahead of print. Affiliations Expand Affiliations 1 Institute for Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin, USA. 2 McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin, USA. Item in Clipboard Emily R Albright et al. mBio. 2021. Show details Display options Display options Format AbstractPubMedPMID doi:…

Continue Reading Human Cytomegalovirus UL138 Protein Inhibits the STING Pathway and Reduces Interferon Beta mRNA Accumulation during Lytic and Latent Infections

KINNEY_DNMT1_METHYLATION_TARGETS

Standard name KINNEY_DNMT1_METHYLATION_TARGETS Systematic name M2508 Brief description Hypomethylated genes in prostate tissue from mice carrying hypomorphic alleles of DNMT1 [GeneID=1786]. Full description or abstract Previous studies have shown that tumor progression in the transgenic adenocarcinoma of mouse prostate (TRAMP) model is characterized by global DNA hypomethylation initiated during early-stage…

Continue Reading KINNEY_DNMT1_METHYLATION_TARGETS

VCV001048762.1 – ClinVar – NCBI

Pathogenic (-) no assertion criteria provided Method: clinical testing Secondary hypothyroidism (Autosomal recessive inheritance) Allele origin: germline Department of Clinical Genetics and Genetic Counseling,Mediscan Systems Accession: SCV001548494.1 Submitted: (Apr 05, 2021) Evidence details Publications PubMed (1) Comment: The p.Ala37LeufsX38 mutation is not reported in the literature so far, however it…

Continue Reading VCV001048762.1 – ClinVar – NCBI

Recombinase Polymerase Amplification/Cas12a-Based Identification of Xanthomonas arboricola pv. pruni on Peach

doi: 10.3389/fpls.2021.740177. eCollection 2021. Affiliations Expand Affiliations 1 Key Laboratory of Horticultural Plant Biology, Ministry of Education, Huazhong Agricultural University, Wuhan, China. 2 Hubei Key Laboratory of Plant Pathology, Huazhong Agricultural University, Wuhan, China. Free PMC article Item in Clipboard Mei Luo et al. Front Plant Sci. 2021. Free PMC article…

Continue Reading Recombinase Polymerase Amplification/Cas12a-Based Identification of Xanthomonas arboricola pv. pruni on Peach

Experimental and Meta-Analytic Validation of RNA Sequencing Signatures for Predicting Status of Microsatellite Instability

doi: 10.3389/fmolb.2021.737821. eCollection 2021. Affiliations Expand Affiliations 1 Laboratory For Clinical and Genomic Bioinformatics, I.M. Sechenov First Moscow State Medical University, Moscow, Russia. 2 Moscow Institute of Physics and Technology, Dolgoprudny, Russia. 3 OmicsWay Corp., Walnut, CA, United States. 4 Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia. 5…

Continue Reading Experimental and Meta-Analytic Validation of RNA Sequencing Signatures for Predicting Status of Microsatellite Instability

Postdoctoral Scholar in Microbiology and Bioinformatics, Cumming School of Medicine – University of Calgary – job portal

University of Calgary Home Prospective Students Current Students Alumni Community Faculty & Staff Home Information for Candidates Opportunities by Type Opportunities by Faculty/Unit Home Information for Candidates Opportunities by Type Opportunities by Faculty/Unit Share this Job: Postdoctoral Scholar in Microbiology and Bioinformatics, Cumming School of Medicine Job ID: 24643 Updated:…

Continue Reading Postdoctoral Scholar in Microbiology and Bioinformatics, Cumming School of Medicine – University of Calgary – job portal

HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs

doi: 10.1093/nar/gkab1221. Online ahead of print. Yang Yang  1   2 , Liwei Zhang  3 , Chaoyang Xiong  2 , Jun Chen  2   4   5 , Li Wang  6 , Zengqi Wen  2   5 , Juan Yu  2 , Ping Chen  4 , Yanhui Xu  6 , Jingji Jin  1   7   8 , Yong Cai …

Continue Reading HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs

Chloroplast genome sequencing based on genome skimming for identification of Eriobotryae Folium | BMC Biotechnology

1. Jiang P, Shi FX, Li MR, Liu B, Wen J, Xiao HX, et al. Positive selection driving cytoplasmic genome evolution of the medicinally important ginseng plant genus Panax. Front Plant Sci. 2018;9:359. doi.org/10.3389/fpls.2018.00359. Article  PubMed  PubMed Central  Google Scholar  2. Takeshi T, Marouane B, Takuya I, Kazusato O, Kimiko…

Continue Reading Chloroplast genome sequencing based on genome skimming for identification of Eriobotryae Folium | BMC Biotechnology

Using STAR SJ.out.tab file to identify novel ncRNAs

Using STAR SJ.out.tab file to identify novel ncRNAs 0 Hi All, I am attempting to identify novel ncRNAs from a circadian RNAseq dataset. Specifically I have a ribo-depleted RNAseq timecourse with 31 samples (sample every 2 hours for 60hrs). I have run STAR (code below). I am trying to follow…

Continue Reading Using STAR SJ.out.tab file to identify novel ncRNAs

ProteoDisco: A flexible R approach to generate customized protein databases for extended search space of novel and variant proteins in proteogenomic studies

doi: 10.1093/bioinformatics/btab809. Online ahead of print. Affiliations Expand Affiliations 1 Cancer Computational Biology Center, Erasmus MC Cancer Institute, University Medical Center, Molewaterplein 40, Rotterdam, 3015 GD, the Netherlands. 2 Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Molewaterplein 40, Rotterdam, 3015 GD, the Netherlands. 3 Department of…

Continue Reading ProteoDisco: A flexible R approach to generate customized protein databases for extended search space of novel and variant proteins in proteogenomic studies

Ethnic Diversity of DPD activity and the DPYD Gene

Plain Language Summary Fluoropyrimidine (FP; 5-FU, capecitabine) is a common chemotherapy used to treat many different cancers, including cancer of the colon and rectum, upper digestive tract, breast and head and neck. Cancer patients who receive FP chemotherapy are at risk of developing severe side effects from their treatment. A…

Continue Reading Ethnic Diversity of DPD activity and the DPYD Gene

Non-genetic determinants of malignant clonal fitness at single-cell resolution

1. Turajlic, S., Sottoriva, A., Graham, T. & Swanton, C. Resolving genetic heterogeneity in cancer. Nat. Rev. Genet. 20, 404–416 (2019). CAS  PubMed  Google Scholar  2. Marine, J. C., Dawson, S. J. & Dawson, M. A. Non-genetic mechanisms of therapeutic resistance in cancer. Nat. Rev. Cancer 20, 743–756 (2020). CAS …

Continue Reading Non-genetic determinants of malignant clonal fitness at single-cell resolution

Adapting Macroecology to Microbiology: Using Occupancy Modeling To Assess Functional Profiles across Metagenomes

doi: 10.1128/mSystems.00790-21. Online ahead of print. Affiliations Expand Affiliation 1 Department of Biology, University of Waterloo, Waterloo, Ontario, Canada. Item in Clipboard Angus S Hilts et al. mSystems. 2021. Show details Display options Display options Format AbstractPubMedPMID doi: 10.1128/mSystems.00790-21. Online ahead of print. Affiliation 1 Department of Biology, University of Waterloo,…

Continue Reading Adapting Macroecology to Microbiology: Using Occupancy Modeling To Assess Functional Profiles across Metagenomes

Mitochondrial mutations in Caenorhabditis elegans show signatures of oxidative damage and an AT-bias

. 2021 Oct 2;219(2):iyab116. doi: 10.1093/genetics/iyab116. Affiliations Expand Affiliations 1 Department of Biology, Colorado State University, Fort Collins, CO 80523, USA and. 2 Department of Integrative Biology, University of Texas at Austin, Austin, TX 78712, USA. Item in Clipboard Gus Waneka et al. Genetics. 2021. Show details Display options Display options…

Continue Reading Mitochondrial mutations in Caenorhabditis elegans show signatures of oxidative damage and an AT-bias

Optimizing sgRNA to Improve CRISPR/Cas9 Knockout Efficiency: Special Focus on Human and Animal Cell

Review doi: 10.3389/fbioe.2021.775309. eCollection 2021. Affiliations Expand Affiliations 1 Plant Biotechnology Department, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran. 2 Department of Psychotherapy, Pirogov Russian National Research Medical University, Moscow, Russia. 3 Medical Faculty, Russian State Social University, Moscow, Russia. 4 Department of Prosthetic Dentistry, I. M….

Continue Reading Optimizing sgRNA to Improve CRISPR/Cas9 Knockout Efficiency: Special Focus on Human and Animal Cell

PhD Bioinformatics, Computer Science, Data Science – Imformatics & Policy, Bibliometrics (m/f/d), Braunschweig – Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH – Computer Sciences

OPEN POSITION32/21 Informatics and policy post-doc (m/f/d) at the Leibniz-Institute DSMZ-German Collection Microorganisms and Cell Cultures GmbH In a new science policy project “Examining Trends in Non-Monetary Benefit-Sharing” (ET-NMBS) funded by the German Federal Agency for Nature Conservation (BfN), we will develop new methods to contribute to the UN Convention…

Continue Reading PhD Bioinformatics, Computer Science, Data Science – Imformatics & Policy, Bibliometrics (m/f/d), Braunschweig – Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH – Computer Sciences

Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease

Significance Cilia are tubulin-based cellular appendages, and their dysfunction has been linked to a variety of genetic diseases. Ciliary chondrodysplasia is one such condition that can co-occur with cystic kidney disease and other organ manifestations. We modeled skeletal ciliopathies by mutating two established disease genes in Xenopus tropicalis frogs. Bioinformatic…

Continue Reading Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease

Biopython Contact Us | Contact Information Finder

Listing Results Biopython Contact Us Biopython · Biopython 2 hours ago Biopython.org View All Biopython. See also our News feed and Twitter. Introduction. Biopython is a set of freely available tools for biological computation written in Python by an international team of developers.. It is a distributed collaborative effort to…

Continue Reading Biopython Contact Us | Contact Information Finder

Presence of male mitochondria in somatic tissues and their functional importance at the whole animal level in the marine bivalve Arctica islandica

1. Karnkowska, A. et al. A eukaryote without a mitochondrial organelle. Curr. Biol. 26, 1274–1284 (2016). CAS  PubMed  Article  Google Scholar  2. John, U. et al. An aerobic eukaryotic parasite with functional mitochondria that likely lacks a mitochondrial genome. Sci. Adv. 5, 1–12 (2019). Article  CAS  Google Scholar  3. Breton,…

Continue Reading Presence of male mitochondria in somatic tissues and their functional importance at the whole animal level in the marine bivalve Arctica islandica

Biopython Contact Map | Contact Information Finder

Listing Results Biopython Contact Map Protein Contact Maps using Biopython Warwick 9 hours ago Warwick.ac.uk View All Protein Contact Maps using Biopython. When working with protein 3D structures, a contact map is usually defined as a binary matrix with the rows and columns representing the residues of two different chains….

Continue Reading Biopython Contact Map | Contact Information Finder

Genome-wide analysis reveals associations between climate and regional patterns of adaptive divergence and dispersal in American pikas

Alexander DH, Novembre J, Lange K (2009) Fast model-based estimation of ancestry in unrelated individuals. Genome Res 19:1655–1664 CAS  PubMed  PubMed Central  Article  Google Scholar  Alexander DH, Shringarpure SS, Novembre J, Lange K (2015) Admixture 1.3 software manual. UCLA Hum Genet Softw Distrib, Los Angeles Google Scholar  Angert AL, Bontrager…

Continue Reading Genome-wide analysis reveals associations between climate and regional patterns of adaptive divergence and dispersal in American pikas

Exploiting genomic surveillance to map the spatio-temporal dispersal of SARS-CoV-2 spike mutations in Belgium across 2020

1. Dudas, G. et al. Virus genomes reveal factors that spread and sustained the Ebola epidemic. Nature 544, 309–315 (2017). ADS  CAS  Article  Google Scholar  2. Kafetzopoulou, L. E. et al. Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak. Science 363, 74–77 (2019). ADS  CAS  Article …

Continue Reading Exploiting genomic surveillance to map the spatio-temporal dispersal of SARS-CoV-2 spike mutations in Belgium across 2020

Bioinformatician I/II/III – Job posted on PostdocJobs.com

Job Description Farmington, Connecticut Apply Summary The Robinson lab is seeking a Bioinformaticician to join our team that focuses on the development of software and ontologies for biomedical research. Our team of expert biological curators, bioinformaticians, and computer scientists maintain and enhance a knowledge extraction and refinement process that delivers…

Continue Reading Bioinformatician I/II/III – Job posted on PostdocJobs.com

highly accurate protein structure prediction with alphafold

In: StatPearls [Internet]. team at our virtual booth on the exhibitor tab. Published online 22 07; DOI: 10.1038/s41586-021-03819-2. Extended Data Fig. Found insideAn important feature of this work is the S-plus subroutines provided for analyzing actual data sets. Coupled with the discussion of new theoretical research, the book should benefit…

Continue Reading highly accurate protein structure prediction with alphafold

Alternate nucleotide is more frequent than reference nucleotide. OMG I’m dizzy. How do I stop the twirl?

This is due to the fact that the very reference genomes that we use for re-alignment are themselves based on individuals who carry rare risk alleles. Thus, when we call variants against these genomes, we are, at many loci, comparing against rare disease risk alleles. As the best/worst example (depending…

Continue Reading Alternate nucleotide is more frequent than reference nucleotide. OMG I’m dizzy. How do I stop the twirl?

Whole genome sequencing and RNA sequencing data analysis for a bacterial strain

Whole genome sequencing and RNA sequencing data analysis for a bacterial strain 1 Hello, I am new RNA sequencing work. I have raw fastq files (from extracted RNA and DNA both) for bacteria “Paucibacter toxinivorans strain IM4”. I am not able to find whole reference genome for the same bacteria….

Continue Reading Whole genome sequencing and RNA sequencing data analysis for a bacterial strain

Optimized two-step electroporation process to achieve efficient non-viral-mediated gene insertion into primary T cells

doi: 10.1002/2211-5463.13292. Online ahead of print. Affiliations Expand Affiliations 1 Cellectis Inc, 430E, 29th street, New York, NY, 10016, USA. 2 8 rue de la croix Jarry, 75013, Paris. Item in Clipboard Ming Yang et al. FEBS Open Bio. 2021. Show details Display options Display options Format AbstractPubMedPMID doi: 10.1002/2211-5463.13292. Online…

Continue Reading Optimized two-step electroporation process to achieve efficient non-viral-mediated gene insertion into primary T cells

Specific targeting of a DNA-alkylating reagent to mitochondria: Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4] benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide – ePrints

Specific targeting of a DNA-alkylating reagent to mitochondria: Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4] benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide Lookup NU author(s): Professor Robert Lightowlers, Dr Paul Smith Downloads Full text for this publication is not currently held within this repository. Alternative links are provided below where…

Continue Reading Specific targeting of a DNA-alkylating reagent to mitochondria: Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4] benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide – ePrints

Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study

. 2021 Sep;39(9):1129-1140. doi: 10.1038/s41587-021-01049-5. Epub 2021 Sep 9. Jonathan Foox  1   2 , Scott W Tighe  3 , Charles M Nicolet  4 , Justin M Zook  5 , Marta Byrska-Bishop  6 , Wayne E Clarke  6 , Michael M Khayat  7   8 , Medhat Mahmoud  7   8 , Phoebe K Laaguiby  3 , Zachary T…

Continue Reading Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study

Identification of immunodominant Bartonella bacilliformis proteins: a combined in-silico and serology approach

Introduction Carrión’s disease is a vector-borne biphasic illness restricted to the South American Andes, with Peru as the most affected country. 1 Gomes C Pons MJ Del Valle Mendoza J Ruiz J Carrion’s disease: an eradicable illness?. The causative agent, Bartonella bacilliformis, is transmitted to humans by sandflies (Lutzomyia spp)….

Continue Reading Identification of immunodominant Bartonella bacilliformis proteins: a combined in-silico and serology approach

Transitional genomes and nutritional role reversals identified for dual symbionts of adelgids (Aphidoidea: Adelgidae)

1. Szathmáry E, Smith JM. The major evolutionary transitions. Nature 1995;374:227–32. PubMed  Google Scholar  2. West SA, Fisher RM, Gardner A, Kiers ET. Major evolutionary transitions in individuality. Proc Natl Acad Sci USA. 2015;112:10112–9. CAS  PubMed  PubMed Central  Google Scholar  3. Moran NA. The coevolution of bacterial endosymbionts and phloem-feeding…

Continue Reading Transitional genomes and nutritional role reversals identified for dual symbionts of adelgids (Aphidoidea: Adelgidae)

A highly-contiguous genome assembly of the Eurasian spruce bark beetle, Ips typographus, provides insight into a major forest pest

1. Edmonds, R. L. & Eglitis, A. The role of the Douglas-fir beetle and wood borers in the decomposition of and nutrient release from Douglas-fir logs. Can. J. Res. 19, 853–859 (1989). Article  Google Scholar  2. Hlásny, T. et al. Living with bark beetles: impacts, outlook and management options. In:…

Continue Reading A highly-contiguous genome assembly of the Eurasian spruce bark beetle, Ips typographus, provides insight into a major forest pest

Comparative genomic analysis of Methanimicrococcus blatticola provides insights into host adaptation in archaea and the evolution of methanogenesis

1. Hackstein JH, Stumm CK. Methane production in terrestrial arthropods. Proc Natl Acad Sci USA. 1994;91:5441–5. CAS  PubMed  PubMed Central  Article  Google Scholar  2. Hackstein JHP, van Alen TA. Fecal methanogens and vertebrate evolution. Evolution. 1996;50:559–72. PubMed  Article  PubMed Central  Google Scholar  3. Borrel G, McCann A, Deane J, Neto…

Continue Reading Comparative genomic analysis of Methanimicrococcus blatticola provides insights into host adaptation in archaea and the evolution of methanogenesis

Reversible electroporation study of realistic normal and cancerous cervical cells model using avalanche transistor-based nanopulse generator

doi: 10.1088/2057-1976/ac240b. Online ahead of print. Affiliations Expand Affiliations 1 Department of Applied Sciences (Biomedical Engineering), Indian Institute of Information Technology Allahabad, Indian Institute Of Information Technology Road, Allahabad, 211012, INDIA. 2 Department of Applied Sciences (Biomedical Engineering), Indian Institute of Information Technology Allahabad, Indian Institute Of Information Technology Road,…

Continue Reading Reversible electroporation study of realistic normal and cancerous cervical cells model using avalanche transistor-based nanopulse generator

An Updated Systematic Review on Focal Therapy in Localized Prostate Cancer: What Has Changed over the Past 5 Years?

Eur Urol. 2021 Sep 3:S0302-2838(21)01949-7. doi: 10.1016/j.eururo.2021.08.005. Online ahead of print. ABSTRACT CONTEXT: Focal therapy is a promising, minimally invasive strategy to selectively treat localized prostate cancer. A previous systematic review indicated that there is growing evidence for favorable functional outcomes, but that oncological effectiveness was yet to be defined….

Continue Reading An Updated Systematic Review on Focal Therapy in Localized Prostate Cancer: What Has Changed over the Past 5 Years?

Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila

1. Sandler, L. & Novitski, E. Meiotic drive as an evolutionary force. Am. Nat. 91, 105–110 (1957). Article  Google Scholar  2. Lindholm, A. K. et al. The ecology and evolutionary dynamics of meiotic drive. Trends Ecol. Evol. 31, 315–326 (2016). Article  PubMed  Google Scholar  3. Lyttle, T. W. Segregation distorters….

Continue Reading Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila

High-throughput DNA sequencing of environmentally insulted latent fingerprints after visualization with nanoscale columnar-thin-film technique

. 2021 Sep;61(5):505-515. doi: 10.1016/j.scijus.2021.06.002. Epub 2021 Jun 7. Affiliations Expand Affiliations 1 Forensic Science Program and Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA. 2 Department of Psychiatry, Yale University School of Medicine & VA CT Healthcare System, New Haven, CT 06511, USA….

Continue Reading High-throughput DNA sequencing of environmentally insulted latent fingerprints after visualization with nanoscale columnar-thin-film technique

kegg pathway database

Pathways that include all genes in gene_ids. Here the KEGG API operations are explained in comparison to these web tools. MODULE — modules or functional units of genes, BRITE — hierarchical classifications of biological entities, This page was last edited on 22 October 2020, at 18:43. The list can be…

Continue Reading kegg pathway database

Short Read-Length Next Generation DNA Sequencing of Antibody CDR Combinations from Phage Selection Outputs

doi: 10.1007/978-1-0716-1450-1_6. Affiliations Expand Affiliations 1 Department of Pathology and Lab Medicine, University of Saskatchewan, Saskatoon, SK, Canada. 2 Department of Pathology and Lab Medicine, University of Saskatchewan, Saskatoon, SK, Canada. ron.geyer@usask.ca. Item in Clipboard Landon Pastushok et al. Methods Mol Biol. 2022. Show details Display options Display options Format AbstractPubMedPMID…

Continue Reading Short Read-Length Next Generation DNA Sequencing of Antibody CDR Combinations from Phage Selection Outputs

Widespread coexistence of self-compatible and self-incompatible phenotypes in a diallelic self-incompatibility system in Ligustrum vulgare (Oleaceae)

Arista M, Berjano R, Viruel J, Ortiz MÁ, Talavera M, Ortiz P (2017) Uncertain pollination environment promotes the evolution of a stable mixed reproductive system in the self-incompatible Hypochaeris salzmanniana (Asteraceae). Ann Bot 120(3):447–456 CAS  PubMed  PubMed Central  Article  Google Scholar  Barrett SC (2019) ‘A most complex marriage arrangement’: recent…

Continue Reading Widespread coexistence of self-compatible and self-incompatible phenotypes in a diallelic self-incompatibility system in Ligustrum vulgare (Oleaceae)

Bioinformatics Scientist (Open Level) – Bild Laboratory job with City of Hope

Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions. About City of HopeCity of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening…

Continue Reading Bioinformatics Scientist (Open Level) – Bild Laboratory job with City of Hope

Validation of Low Coverage Whole Genome Sequencing for Mitochondrial DNA Variants Suggests Mitochondrial DNA as a Genetic Cause of Preterm Birth

doi: 10.1002/humu.24279. Online ahead of print. Zeyu Yang  1 , Jesse Slone  1 , Xinjian Wang  1 , Jack Zhan  1 , Yongbo Huang  2 , Bahram Namjou  2 , Kenneth M Kaufman  2   3 , Michael Pauciulo  1 , John B Harley  2   3 , Louis J Muglia  1   4 , Iouri Chepelev  2 , Taosheng Huang …

Continue Reading Validation of Low Coverage Whole Genome Sequencing for Mitochondrial DNA Variants Suggests Mitochondrial DNA as a Genetic Cause of Preterm Birth

Sequencing analysis of exons 5 and 6 in RUNX2 in non-syndromic patients with supernumerary tooth in Kelantan, Malaysia

doi: 10.1007/s00784-021-04098-x. Online ahead of print. Affiliations Expand Affiliations 1 Department of Pediatric Dentistry, Hospital Raja Permaisuri Bainun, 30450, Ipoh, Perak, Malaysia. 2 School of Dental Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. 3 School of Dental Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. kannan@usm.my. 4…

Continue Reading Sequencing analysis of exons 5 and 6 in RUNX2 in non-syndromic patients with supernumerary tooth in Kelantan, Malaysia

Frontiers | DNA Methylation and RNA-Sequencing Analysis Show Epigenetic Function During Grain Filling in Foxtail Millet (Setaria italica L.)

Introduction Gene expression is not only controlled by DNA sequences but also by epigenetic marks in eukaryotes. DNA methylation as one of the important epigenetic modifications has been demonstrated as closely related to gene expression in biological processes, such as transcriptional activity, developmental regulation, and environmental responses (Maunakea et al.,…

Continue Reading Frontiers | DNA Methylation and RNA-Sequencing Analysis Show Epigenetic Function During Grain Filling in Foxtail Millet (Setaria italica L.)

A Biopython-based method for comprehensively searching for eponyms in Pubmed

doi: 10.1016/j.mex.2021.101264. eCollection 2021. Affiliations Expand Affiliations 1 Department of Pathology, University of Colorado School of Medicine, Aurora, CO, USA. 2 Department of Pathology & Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. 3 Department of Pathology and the Eugene McDermott Center for Human…

Continue Reading A Biopython-based method for comprehensively searching for eponyms in Pubmed

Phytochemistry reflects different evolutionary history in traditional classes versus specialized structural motifs

1. Thompson, J. N. & Pellmyr, O. Evolution of oviposition behavior and host preference in Lepidoptera. Annu. Rev. Entomol. 36, 65–89 (1991). Article  Google Scholar  2. Bowers, M. D. Iridoid glycosides and host-plant specificity in larvae of the buckeye butterfly, Junonia coenia (Nymphalidae). J. Chem. Ecol. 10, 1567–1577 (1984). CAS …

Continue Reading Phytochemistry reflects different evolutionary history in traditional classes versus specialized structural motifs

Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance

1. Lee, M.-R. et al. Mycobacterium abscessus complex infections in humans. Emerg. Infect. Dis. 21, 1638–1646 (2015). CAS  PubMed  PubMed Central  Google Scholar  2. Prince, D. S. et al. Infection with Mycobacterium avium complex in patients without predisposing conditions. N. Engl. J. Med. 321, 863–868 (1989). CAS  PubMed  Article  Google…

Continue Reading Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance

Validation of gene editing efficiency with CRISPR-Cas9 system directly in rat zygotes using electroporation mediated delivery and embryo culture

doi: 10.1016/j.mex.2021.101419. eCollection 2021. Affiliations Expand Affiliations 1 Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA. 2 Cystic Fibrosis Research Center, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. Free PMC article Item in Clipboard Anil K Challa et al….

Continue Reading Validation of gene editing efficiency with CRISPR-Cas9 system directly in rat zygotes using electroporation mediated delivery and embryo culture

Genome of a middle Holocene hunter-gatherer from Wallacea

1. McColl, H. et al. The prehistoric peopling of Southeast Asia. Science 361, 88–92 (2018). CAS  PubMed  Article  ADS  Google Scholar  2. Hasanuddin. Gua Panningnge di Mallawa, Maros: kajian tentang gua hunian berdasarkan artefak batu dan sisa fauna. Naditira Widya 11, 81–96 (2017). Article  Google Scholar  3. Bulbeck, D., Pasqua,…

Continue Reading Genome of a middle Holocene hunter-gatherer from Wallacea

Ca 2+ roles in electroporation-induced changes of cancer cell physiology: From membrane repair to cell death

. 2021 Aug 13;142:107927. doi: 10.1016/j.bioelechem.2021.107927. Online ahead of print. Affiliations Expand Affiliations 1 Biophysical Research Group, Faculty of Natural Sciences, Vytautas Magnus University, Vileikos st. 8, LT 44404 Kaunas, Lithuania. 2 Departament of Bioelectronics, Mines Saint-Etienne, 880 route de Mimet, Gardanne 13541, France. 3 Biophysical Research Group, Faculty of…

Continue Reading Ca 2+ roles in electroporation-induced changes of cancer cell physiology: From membrane repair to cell death

Resistance training rejuvenates the mitochondrial methylome in aged human skeletal muscle

doi: 10.1096/fj.202100873RR. Bradley A Ruple  1 , Joshua S Godwin  1 , Paulo H C Mesquita  1 , Shelby C Osburn  1 , Christopher G Vann  1 , Donald A Lamb  2 , Casey L Sexton  1 , Darren G Candow  3 , Scott C Forbes  4 , Andrew D Frugé  2 , Andreas N Kavazis  1 , Kaelin C Young …

Continue Reading Resistance training rejuvenates the mitochondrial methylome in aged human skeletal muscle

A Combined Digital PCR and Next Generation DNA-Sequencing Based Approach for Tracking Nearshore Pollutant Dynamics Along the Southwest United States/Mexico Border

doi: 10.3389/fmicb.2021.674214. eCollection 2021. Affiliations Expand Affiliations 1 Southern California Coastal Water Research Project, Costa Mesa, CA, United States. 2 BioTechnology Institute, University of Minnesota Twin Cities, Saint Paul, MN, United States. 3 Department of Soil, Water, and Climate, University of Minnesota Twin Cities, Saint Paul, MN, United States. 4…

Continue Reading A Combined Digital PCR and Next Generation DNA-Sequencing Based Approach for Tracking Nearshore Pollutant Dynamics Along the Southwest United States/Mexico Border

Whole exome sequencing reveals a homozygous C1QBP deletion as the cause of progressive external ophthalmoplegia and multiple mtDNA deletions

Case Reports . 2021 Jul 4;S0960-8966(21)00176-0. doi: 10.1016/j.nmd.2021.06.014. Online ahead of print. Le Guo  1 , Periyasamy Govindaraj  2 , Mariëlle Kievit  3 , Irenaeus F M de Coo  1 , Mike Gerards  4 , Debby M E I Hellebrekers  5 , Alphons P M Stassen  5 , Narayanappa Gayathri  6 , Arun B Taly  7 , Bindu Parayil…

Continue Reading Whole exome sequencing reveals a homozygous C1QBP deletion as the cause of progressive external ophthalmoplegia and multiple mtDNA deletions

How to Download Big Data for Data Science Projects Free of Cost

Check some top popular websites to download the free datasets available for various areas such as natural language processing, computer vision, and domain-specific sciences. So, if you are in Machine learning, Artificial intelligence, or other Data science projects, this article may be beneficial for you. Nowadays, the world is becoming…

Continue Reading How to Download Big Data for Data Science Projects Free of Cost