Tag: SBS

Mutational signatures of cancer: Can passenge

“[…] mutational signatures are not only genomic noise of passenger mutations, but they provide etiological and biological information on carcinogenesis.” BUFFALO, NY- January 19, 2024 – A new editorial paper was recently published in Oncoscience (Volume 10), by researcher Peeter Karihtala from the University of Helsinki and University Hospital Comprehensive…

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Whole-genome sequencing reveals the molecular implications of the stepwise progression of lung adenocarcinoma

Whole-genome sequencing (WGS) analysis of early and advanced adenocarcinomas Whole-genome short read and long read sequencing datasets of 76 lung cancer specimens were analyzed. The datasets included newly generated data for 48 early small-sized lung adenocarcinoma cases (collectively called “Early-Ad” hereafter). These cases included 26 AIS (9 and 17 cases…

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NGS Sample Preparation Market Surges with a Remarkable 13.7% CAGR, Setting Sights on US$ 5442.1 Million by 2032-FMI Projection

PRESS RELEASE Published December 15, 2023 NGS Sample Preparation Market The value of the global NGS sample preparation market growth is projected to rise at a compound annual growth rate (CAGR) of 13.7% from 2022 to 2032, from US$ 1321.8 million in 2022 to US$ 5441.1 million in 2032. The…

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Illumina: Grail’s Divestment Could Unlock Significant Shareholder Value (NASDAQ:ILMN)

anamejia18/iStock via Getty Images Illumina (NASDAQ:ILMN) has been one of the worst performers in the S&P Health Care Select Fund (XLV), falling 40% in 2023 alone. Illumina’s market cap has fallen from over $75 billion to just $18 billion at the time of this writing, representing an 80% decline from…

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Fapon VP/SVP/CSO/CTO – Nanopore sequencing, LUNAR BIOSCIENCES

Fapon is an industry-leading IVD platform organization that offers an unmatched product and service combination of innovative biomarkers and bioactive raw materials, and one-stop solutions of Open Instrument Systems and Reagents, with our mission to enable earlier disease identification and more convenient, accurate, and affordable diagnosis. Nowadays, we have well…

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Next Generation Sequencers Market Growth Research Report [2024-2031]

PRESS RELEASE Published December 5, 2023 “Next Generation Sequencers Market” Research Report Provides Detailed Historical Analysis of Global market for Next Generation Sequencers from 2017 2022, and provides Extensive Market Forecasts From 2024 2031 By Applications (Diagnostics, Drug Discovery, Biomarker Discovery, Others),Types (Sequencing by Synthesis (SBS), Ion Semiconductor Sequencing, Single-Molecule…

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RNA Sequencing Market Top Growth Companies, Global Growth, Size, Trends, Industry Analysis, Key Players by 2032

RNA Sequencing Market Report PORTLAND, OREGON, UNITED STATES, November 24, 2023 /EINPresswire.com/ — Allied Market Research published an exclusive report RNA Sequencing Market, which includes a detailed analysis based on competitors and important market segments (2023-2032). The market scenario is analyzed using Porter’s five forces model. This model explains the…

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Sequencing 101: Tandem repeats – PacBio

In the field of genetics, the concept of tandem repeats has been both scientifically fascinating, experimentally challenging, and motivating for technology development. As DNA sequencing technologies and analysis tools have evolved, scientists are now able to reveal the secrets hidden within these repetitive sequences, shedding light on their significance in…

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Mutational spectra are associated with bacterial niche

Bacteria exhibit diverse mutational spectra Using a specifically-developed open-source bioinformatic tool, MutTui (github.com/chrisruis/MutTui), we analysed whole genome sequence alignments and phylogenetic trees to reconstruct single base substitution (SBS) mutational spectra of 84 phylogenetic clades from 31 diverse bacterial species representing a broad range of phylogenetic diversity and replication sites (Figs. S1…

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What is Next Generation Sequencing (NGS)?

History of Next-generation Sequencing Next Generation Sequencing (NGS) is a revolutionary genetic analysis technique that involves fragmenting the genetic material (DNA or RNA) and attaching oligonucleotides with known sequences through a process called adapter ligation. This allows the resulting fragments to interact with the selected sequencing platform. Subsequently, the bases within…

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miRNA Sequencing And Assay Market

miRNA, also known as microRNA, are small noncoding RNA molecules that regulate gene expression. The market for miRNA sequencing and assay market revolves around the technologies and methodologies used to study these RNA molecules, which have been linked to numerous disease mechanisms and are frequently the subject of innovative therapeutic…

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NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology

Patient characteristics and tissue context The clinical interpretation of molecular alterations starts with evaluating relevant patient characteristics and the tissue context in which a genetic profile occurs. The former relates, in particular, to previous therapies, in addition to disease stage and clinical performance status. For example, prior targeted therapies warrant…

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Analytical Scientist in Bioinformatics Software/Pipeline Development at The Institute of Cancer Research

Job Details Under the leadership of Dr Syed Haider, we are seeking to appoint a highly motivated analytical scientist with experience in genomic and transcriptomic data analysis to join our Breast Cancer Research Bioinformatics Group. We employ cutting-edge data-mining techniques in collaboration with experimental investigators to identify new molecular markers of breast…

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how to deal with Gs?

Small RNA sequencing using Illumina 2 channel SBS: how to deal with Gs? 1 I’m working on a small RNA sequencing experiment (150 PE on NovaSeq 6000), and many reads look like this when the fragment size is smaller than 150 bp, with Gs completing the sequence up to 150:…

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The Age of Aquarius – RNA, the Epicenter of Genetic Information

The veil on genetic information was lifted by the advent of gene cloning and sequencing technologies in the 1970s. The discovery and purification of bacterial nucleases capable of cutting DNA at specific sequences and ligases capable of joining them enabled DNA from any species – or mRNAs converted to complementary…

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Compute In The MiSeq and Ion Torrent PGM

Compute in the MiSeq and Ion Torrent PGM I thought it would be fun to quickly compare the compute in the Ion Torrent PGM and MiSeq. On the surface these are very similar instruments, both released around 2010. And both generating in the range of “a few million reads”. But…

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NGS one-liner to call variants

Tutorial:NGS one-liner to call variants 0 This is a tutorial about creating a pipeline for sequence analysis in a single line. It is made for capture/amplicon short read sequencing in mind for human DNA and tested with reference exome sequencing data described here. I share the process and debuging steps…

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NGS oneliner

Tutorial:NGS oneliner 0 This is a tutorial about creating a pipeline for sequence analysis in a single line.I share the process and debuging steps gone through while putting it together.Source is available at: github.com/barslmn/ngsoneliner/I couldn’t make a longer post, complete version of this post: omics.sbs/blog/NGSoneliner/NGSoneliner.html Pipeline # fastp –in1 “$R1″…

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Takeda Announces Topline Results of Phase 3 ADMIRECD II Trial of Alofisel darvadstrocel in Complex Crohns Perianal Fistulas

Osaka, Japan & Cambridge, Mass., United States:   Takeda (TSE:4502/NYSE: TAK) today announced that the Phase 3 ADMIRE-CD II study, assessing the efficacy and safety of Alofisel® (darvadstrocel) for the treatment of complex Crohn’s Perianal Fistulas (CPF), did not meet its primary endpoint of combined remission…

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Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel in Complex Crohn’s Perianal Fistulas -October 18, 2023 at 09:35 am EDT

OSAKA – Takeda (TSE:4502/NYSE: TAK) today announced that the Phase 3 ADMIRE-CD II study, assessing the efficacy and safety of Alofisel (darvadstrocel) for the treatment of complex Crohn’s Perianal Fistulas (CPF), did not meet its primary endpoint of combined remission at 24 weeks, based on topline data. The safety profile…

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NGS Sample Preparation Industry Envisions a 13.7% CAGR Surge to US$ 5442.1 Million by 2032 | Future Market Insights,Inc.

The global NGS Sample Preparation Industry  is expected to be valued at US$ 5441.1 million by 2032, up from US$ 1321.8 million in 2022, and to grow at a 13.7% CAGR during the forecast period (2022 to 2032). DNA contains the blueprints of life. Within its structures are the codes required…

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NGS Sample Preparation Market worth $6.80 billion by 2030,

NGS Sample Preparation Market | 360iResearch The “NGS Sample Preparation Market by Product (Reagents & Consumables, Workstations), Workflow (DNA, Library Preparation, Quality Control), Technology, Application, End-User – Global Forecast 2023-2030” report has been added to 360iResearch.com‘s offering. Request Sample Copy of this Report @ www.360iresearch.com/library/intelligence/ngs-sample-preparation?utm_source=openpr&utm_medium=referral&utm_campaign=sample Market Segmentation & Coverage: This…

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Zealand Pharma, Boehringer Ingelheim Begin Phase 3 Trials for Obesity Drug Candidate Survodutide -October 05, 2023 at 08:00 am EDT

Zealand Pharma A/S is a Denmark-based biotechnology company. The Company is focused on the discovery, design and development of peptide-based medicines for metabolic and gastrointestinal diseases and other rare disease areas with unmet medical needs. The Company’s peptide-based product candidates includes clinical development, registration and, potentially, commercialization. Its pipeline includes…

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DNA giant in troubled waters

A botched acquisition deal and unrest among company investors amid plummeting stocks have plagued Illumina, which was once part of the biotech big leagues that dominated the field of gene sequencing. Now, in fear of losing its ground to other players in the space, it might also have to cough…

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Clinical Next-Generation Sequencing (NGS) Data Analysis Market estimated valuation of US$ 13.1 Billion by 2033 Growth Accelerating with Increasing Adoption of NGS Sequencing Services: FMI

As per Future Market Insights’ latest industry analysis, the valuation for the global Clinical Next-Generation Sequencing (NGS) Data Analysis Market was around US$ 2.3 Billion in 2022, and the market is projected to exhibit growth at a CAGR of 17.4% over the forecast period, with an estimated valuation of around…

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DNA-bridging by an archaeal histone variant via a unique tetramerisation interface

Chromatin isolation and MNase digestion M. jannaschii DSM 2661 cells were grown in 100 l fermenters in minimal medium containing 0.3 mM K2HPO4, 0.4 mM KH2PO4, 3.6 mM KCl, 0.4 M NaCl, 10 mM NaHCO3, 2.5 mM CaCl2, 38 mM MgCl2, 22 mM NH4Cl, 31 µM Fe(NH4)2(SO4)2, 1 mM C6H9NO6, 1.2 µM MgSO4, 0.4 mM CuSO4, 0.3 µM MnSO4, 36 nM FeSO4, 36 nM CoSO4, 3.5 nM…

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Illumina: The Measurement Monopoly – by Elliot Hershberg

Welcome to The Century of Biology! This newsletter explores data, companies, and ideas from the frontier of biology. You can subscribe for free to have the next post delivered to your inbox: Enjoy! 🧬 No technology has ever improved more rapidly than DNA sequencing. The resulting explosion of genomic data…

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2023 Microbiome Sequencing Services Market Is Booming Worldwide | Exclusive Report

The recently published Microbiome Sequencing Services Market Report 2023, spanning 122pages, offers a comprehensive overview of the market’s current state, size, volume, and market share. In today’s rapidly evolving business landscape, staying informed about the Microbiome Sequencing Services Market is essential for businesses and marketers alike. This report is a…

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Roche hiring Principal Scientist I Bioinformatics in Mississauga, Ontario, Canada

The PositionRoche Sequencing Solutions (RSS), a business within Roche Diagnostics, focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist in the NGS Algorithms and Applications team to support…

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Illumina MISEQ SY-410-1003 – France

Listing description Illumina MISEQ SY-410-1003 Last maintenance October 2022 done by Illumina Price is negotiable Illumina’s MiSeq uses sequencing by synthesis (SBS) technology: cluster generation+ sequencing+ data analysis in a very short time. Key features: – Automation: Miseq includes a buffer bottle, flow cell and reagent cartridge, enabling both cluster…

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The global microbiome sequencing service market is expected to reach an estimated $2.4 billion by 2028 with a CAGR of 12.4% from 2023 to 2028

ReportLinker Trends, opportunities, and forecast for the global microbiome sequencing service market from 2017 to 2028 market by technology (sequencing by synthesis (SBS), sequencing by ligation (SBL), nanopore sequencing, sanger sequencing, and others), type (amplicon sequencing, whole-genome sequencing, shotgun sequencing, and others), end use industry (pharmaceutical and biotechnology companies, academic…

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Clinical Oncology Next Generation Sequencing (NGS) Market

Clinical Oncology Next Generation Sequencing Market The Global Clinical Oncology Next Generation Sequencing Market Size was valued at USD 339.10 million in 2022 and is predicted to reach USD 1.18 billion by 2030, increasing at a CAGR of +14% from 2023 to 2030. Next-generation sequencing is a technique that helps…

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2023 Microbiome Sequencing Services Market Size and Trends| Market Updates and Regional Analysis till 2030

The Global “Microbiome Sequencing Services Market” Informational Report provides an in-depth examination of market dynamics to help businesses make strategic decisions. It facilitates trend anticipation by assessing major key players performance, profiles, growth prospects, and regional impacts. This research equips organizations with the knowledge they need to understand the landscape…

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PolyA and PolyG sequences in FastQC/MultiQC report

Hello, We sent our samples off for RNA exome sequencing. We normally do mRNA sequencing but our RNA was degraded so RNA exome sequencing was recommended. We used the TruSeq RNA Exome kit. I am encountering issues I haven’t experienced before when trimming reads. Below is the adapter content from…

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Jaguar Health to Present September 7 at Emerging Growth Conference and at the September 11-13 H.C. Wainwright Annual Global Investment Conference

Napo Pharmaceuticals, a Jaguar family company, reported completion August 17 of last patient last visit for its pivotal Phase 3 OnTarget trial of crofelemer for preventive treatment of cancer therapy-related diarrhea SAN FRANCISCO, CA / ACCESSWIRE / August 28, 2023 / Jaguar Health, Inc. (NASDAQ:JAGX) today announced that Lisa Conte,…

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Europe Transfection Reagent and Equipment Market Share, Demand, Industry Trends, Growth Opportunities and Revenue Outlook

PRESS RELEASE Published August 28, 2023 Data Bridge Market research has a newly released expansive study titled “Europe Transfection Reagent and Equipment Market ” which guarantees you will remain better informed than your competition. This study provides a broader perspective of the marketplace with its comprehensive market insights and analysis…

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Liquid biopsy – PacBio

Why SBB for liquid biopsy sequencing? Variant detection performance was tested for SBB and SBS sequencing using the SeraCare complete ctDNA mutation mix across five variant allele frequencies: 0% (WT), 0.05%, 0.1%, 0.25%, and 0.5%. The Onso system achieved nearly double the sensitivity for rare variant detection with equivalent coverage…

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Zealand Pharma Announces Financial Results for the First Half of 2023

Company announcement – No. 28 / 2023 Zealand Pharma Announces Financial Results for the First Half of 2023 Strong progress across R&D pipeline and significant strengthening of the balance sheet Boehringer Ingelheim to move into Phase 3 trials with GCGR/GLP-1R dual agonist survodutide (BI456906) in obesity following positive Phase…

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Principal Scientist II Bioinformatics – Hiring Now at F. Hoffmann-La Roche Ltd in Mississauga, ON

We are searching for a persistent Principal Scientist II Bioinformatics to join our energetic team at F. Hoffmann-La Roche Ltd in Mississauga, ON.Growing your career as a Full Time Principal Scientist II Bioinformatics is an incredible opportunity to develop key skills.If you are strong in leadership, critical thinking and have…

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Illumina, Inc. (NASDAQ:ILMN) Q2 2023 Earnings Call Transcript

Illumina, Inc. (NASDAQ:ILMN) Q2 2023 Earnings Call Transcript August 10, 2023 Operator: Good day, ladies and gentlemen, and welcome to the Second Quarter 2023 Illumina Earnings Conference Call. At this time, all participants are in a listen-only mode. After the speakers’ presentation, there will be a question-and-answer session. Please be…

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Amplifying Insights: Anticipating a 13.7% CAGR Surge to US$ 5442.1 Million by 2032 in the NGS Sample Preparation Market

The global NGS Sample Preparation Market is expected to be valued at US$ 5441.1 million by 2032, up from US$ 1321.8 million in 2022, and to grow at a 13.7% CAGR during the forecast period (2022 to 2032). DNA contains the blueprints of life. Within its structures are the codes…

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NGS-based RNA-sequencing Market worth $5.5 billion by 2027

PRESS RELEASE Published August 8, 2023 “NGS-based RNA-sequencing Market in terms of revenue was estimated to be worth $2.5 billion in 2022 and is poised to reach $5.5 billion by 2027, growing at a CAGR of 17.2% from 2022 to 2027 according to a new report by MarketsandMarkets™” Browse 166…

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Sequencing 101: SBB sequencing – PacBio

Since the inception of next generation sequencing (NGS) more than a decade ago, short-read sequencing accuracy has seen only marginal improvement. Having achieved a level of precision thought to be “good enough” for most applications, much of NGS development has been focused on optimizing for cost and throughput. As a…

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Next-Generation Sequencing in Plant Breeding: Challenges and Possibilities

Abdi, H. (2007). Discriminant correspondence analysis. In N. J. Salkind (Ed.), Encyclopedia of measurement and statistic (pp. 270–275). Sage. Google Scholar  Ando, K., Carr, K. M., & Grumet, R. (2012). Transcriptome analyses of early cucumber fruit growth identifies distinct gene modules associated with phases of development. BMC Genomics, 13, 518….

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Next Generation Sequencers Market Current Size, Development and Growth Prospects

The Global Next Generation Sequencers Market study with 96+ market data Tables, Pie charts & Figures is now released by HTF MI. The research assessment of the Market is designed to analyze futuristic trends, growth factors, industry opinions, and industry-validated market facts to forecast till 2029. The market Study is…

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Global Microbiome Sequencing Services Market Size Envisaged to Reach USD 1,032.39 Million By 2032, at 15.3% CAGR Growth: Polaris Market Research

Polaris Market Research conducted a comprehensive research study spanning over [+110] pages, revealing that the global microbiome sequencing services market size/share was valued at USD 248.31 Million in 2022. The study further indicates that the market will grow at a compound annual growth rate (CAGR) of 15.3% and is projected…

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Next Generation Sequencing Market is projected to grow at a

Visiongain has published a new report entitled Next Generation Sequencing Market Report 2023-2033: Forecasts by Type (Consumables, Bioinformatics, Sequencing Services, Pre-sequencing Services, Instruments), by Workflow (Library Preparation, Sequencing, Data Analysis), by Application (Oncology, Reproductive Health, Genetic and Rare Diseases, Consumer Genomics, Agrigenomics & Forensics, Others), by End-use (Hospitals and Clinics,…

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Next Generation Sequencing (NGS) Informatics Market to be

Redding, California, July 26, 2023 (GLOBE NEWSWIRE) — According to a new market research report titled, ‘Next Generation Sequencing (NGS) Informatics Market by Offering (Data Analysis, Interpretation & Reporting, Storage & Computing, LIMS) Application (Diagnostic, Drug Discovery, Precision Medicine, Biomarker Discovery), and End User – Global Forecast to 2030,’ published…

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Global Microbiome Sequencing Services Market Size and Forecast

New Jersey, United States – Verified Market Research recently released a research report titled “Global Microbiome Sequencing Services Market Insight, Forecast.” The report extensively discusses the Global Microbiome Sequencing Services market, offering readers a comprehensive understanding of key trends, top strategies, and potential growth opportunities. It incorporates Porter’s Five Forces analysis,…

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Faculty of Forestry SKUAST-K concludes 5-day training prog on R Studio

Faculty of Forestry SKUAST-K concludes 5-day training prog on R Studio Post by RK News on Tuesday, July 18, 2023 Srinagar, July 18: Division of Social and Basic Sciences, Faculty of Forestry, SKUAST-K on Tuesday concluded the five-day training program on R Studio. The main objectives of the program were…

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Beyond borders: The 2023 Discoveries Roadshow ignites curiosity worldwide

Scientific breakthroughs are rarely achieved in isolation. They require collaboration, cutting-edge techniques, and a platform where scientists can come together to exchange knowledge and explore groundbreaking tools. And that’s exactly what the 2023 PacBio Discoveries Roadshow delivered… The 2023 Roadshow in the Americas and Europe left a lasting impression.  The…

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NGS Library Preparation Market to Reach $6.47 Billion by

Redding, California, July 17, 2023 (GLOBE NEWSWIRE) — According to a new market research report titled, ‘NGS Library Preparation Market By Product (Kits, Reagents, Instruments), Sequencing Type (Genome, Exome, Targeted), Application (Diagnostics, Discovery), End User (Hospitals, Diagnostic Laboratories, Pharmaceutical, Academic) – Global Forecast to 2030,’ published by Meticulous Research®, the…

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Stellar Expansion Predicted for Global Microbiome Sequencing Services Market as New Drug (IND) Requirements for Fecal Microbiota and Technological Innovations Offer Immense Opportunities

Company Logo Global Microbiome Sequencing Services Market Global Microbiome Sequencing Services Market Dublin, July 17, 2023 (GLOBE NEWSWIRE) — The “Global Microbiome Sequencing Services Market (2023-2028) by Technology, Laboratory, Research, Products & Services, Application, End-User, Geography and Competitive Analysis” report has been added to ResearchAndMarkets.com‘s offering. In a recent examination…

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Capability of the iSeq 100 sequencing system from Illumina to detect low-level substitutions in the human mitochondrial genome

Introduction Massively parallel sequencing (MPS) technologies allow for a more accurate and precise determination of the heteroplasmy level (i.e., the coexistence of different nucleotide variants in the same mtDNA position) in mitochondrial genomes compared with the traditional dideoxy method. Even mtDNA minority variants that are below the dideoxy sequencing detection…

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Gene Synthesis Market Latest Report on the Current Trends and Future Opportunities to 2030 Prominent Players are Genescript, GeneArt (Thermofischer), IDT

The Gene Synthesis Market study with 100+ market data Tables, Pie charts & Figures is now released by Infinity Business Insights. The market research report for the Gene Synthesis industry offers a detailed analysis of the business chain structure and provides insights into the industry’s environment. It presents market size…

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DNA Polymerase Market Size, Revenue Analysis, Industry Outlook, Forecast, 2023-2030

Rise in number of genetic disorder-based researches and increasing adoption of Taq DNA Polymerase for thermal tolerance and high efficiency are some of the key factors driving market revenue growth The global DNA polymerase market size is expected to reach USD 568.3 Million in 2030 and register a revenue CAGR of 6.4%…

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The microbiome sequencing services market is projected to

New York, July 06, 2023 (GLOBE NEWSWIRE) — Reportlinker.com announces the release of the report “Microbiome Sequencing Services Market by Service, Type, Technology, End User – Global Forecast to 2028” – www.reportlinker.com/p04933548/?utm_source=GNW These applications have the potential to advance the understanding of the role of microbiota in health and disease…

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Next Generation Sequencing (NGS) Market to be Worth $27.5

Redding, California, July 06, 2023 (GLOBE NEWSWIRE) — According to a new market research report, “Next Generation Sequencing (NGS) Market by Offering (Kits [Library Prep, QC, DNA Extraction], System) Type (Genome, Exome, Targeted) Application (Reproductive, Oncology, Infectious) Technology (SBS, Nanopore, Nanoball, SMRT Seq) – Global Forecast to 2030”, published by…

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Principal Scientist I Bioinformatics job with F. Hoffmann-La Roche AG

The Position Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist in the NGS Algorithms and Applications team to…

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Genomic characteristics of triple negative apocrine carcinoma: a comparison to triple negative breast cancer

Baseline characteristics We described the baseline clinical and pathological characteristics of TNAC and LK-TNBC in Supplementary Table 1. Only stage at diagnosis was different between TNAC and LK-TNBC (P = 0.03), while no significant differences were observed in other characteristics, including nuclear grade, histologic grade, Ki-67, and status of (neo)adjuvant treatment. Somatic…

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Solution reagent kit – MiSeq FGx – Verogen

Generate high-quality sequencing data with MiSeq FGx Sequencing Reagents. These pre-filled, ready-to-use cartridges leverage gold-standard sequencing-by-synthesis (SBS) chemistry to support a range of laboratory throughput requirements. MiSeq FGx Sequencing Reagents support both Forensic Genomics and Research Use Only modes on the MiSeq FGx Sequencing System to simplify inventory and ordering…

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Senior Principal Bioinformatics Scientist, NGS Algorithms job with F. Hoffmann-La Roche AG

The Position Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist in the NGS Algorithms and Applications team to…

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Next-Generation Sequencing (NGS) Market Size 2023-2028, Industry Trends and Latest Insights

PRESS RELEASE Published June 29, 2023 IMARC Group has recently released a new research study titled “Next-Generation Sequencing (NGS) Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2023-2028”, offers a detailed analysis of the market drivers, segmentation, growth opportunities, trends and competitive landscape to understand the current and…

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Microbiome Sequencing Services Market 2023

IMARC Group, a leading market research company, has recently releases report titled, “Microbiome Sequencing Services Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2023-2028“, The study provides a detailed analysis of the industry, including the global microbiome sequencing services market share, size, trends, and growth forecasts. The report also includes competitor…

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Sequencing by Synthesis on the Illumina NovaSeqXTM Series

Sequencing by Synthesis on the Illumina NovaSeqXTM Series The NovaSeqXTM Plus sequencing system is the latest in next-generation sequencing technology and builds on Illumina’s well-established sequencing workflow for higher throughput and accuracy, enabling larger-scale genomic studies. The NovaSeqX Plus platform can produce up to 16 Tb output or up to…

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Fapon SVP/Chief Scientific Officer (CSO)

Fapon is an industry-leading IVD platform organization that offers an unmatched product and service combination of innovative biomarkers and bioactive raw materials, and one-stop solutions of Open Instrument Systems and Reagents, with our mission to enable earlier disease identification and more convenient, accurate, and affordable diagnosis. Nowadays, we have well…

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Proton and alpha radiation-induced mutational profiles in human cells

Determining proton and helium ion fraction, and irradiating the cell lines The dosage of radiation was determined experimentally in order to achieve between 40 and 50% lethality (corresponding to 50% to 60% clonogenic survival), independently across the two types of particle beams (Fig. 1a,b). Figure 1 Overview of the experimental design….

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Senior Principal Scientist Bioinformatics job with F. Hoffmann-La Roche AG

The Position Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist in the NGS Algorithms and Applications team to…

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Microbiome Sequencing Services Market: Competitive Landscape and Recent Industry Development Analysis 2023-2032

Microbiome Sequencing Services Market Growing Demand and Growth Opportunity 2023-2032 QMI has released the latest report on Microbiome Sequencing Services Market Analysis 2023. A detailed study accumulated to offer the latest insights about acute features of the Microbiome Sequencing Services market. The report contains different market predictions related to revenue…

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SBS Mutational Signatures aetiology

SBS Mutational Signatures aetiology 0 Hello, I was working with some mutational signatures, until now I used this cosmic page to search the signature proposed aetiology cancer.sanger.ac.uk/signatures/sbs/ I looked in the downloads but i didn’t found a table with the signature name and it’s aetiology. Is there any reference with…

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SENP2 restrains the generation of pathogenic Th17 cells in mouse models of colitis

Mice Senp2f/f mice were described as previously16. T cell-specific Senp2 knockout mice (CKO, Senp2f/fLckCre+/+) and control mice (WT, LckCre+/+) in C57BL/6 genetic background were raised and kept in the Academia Sinica SPF animal facility, according to the rule of the Animal Protection Act of Taiwan. Lck-Cre mice, Rag2−/− mice and CD45.1…

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Computer Vision/Deep Learning Scientist – SBS Corp.

Computer Vision/Deep Learning ScientistRemote DescriptionComputer Vision/Deep Learning Scientist work with various product teams across various business units to define high-impact business problems, solve them using novel techniques, and execute and monitor them throughout their lifecycle.Require to design, develop, and implement novel computer vision algorithms for unique use cases.Evaluate accuracy and…

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Principal Scientist I Bioinformatics Job Opening in Santa Clara, CA at Roche Holdings Inc.

The Position Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist in the NGS Algorithms and Applications team to…

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Third Generation Sequencing Market Set to Witness

LONDON, June 06, 2023 (GLOBE NEWSWIRE) — The newest report from Data Bridge Market Research, “Third Generation Sequencing Market” examines growth strategies, drivers, opportunities, key segments, Porter’s Five Forces analysis, and the competitive environment in detail. In order to thrive in the rapidly evolving marketplace, businesses today require innovative and…

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A Guide to DNA Sequencers

DNA sequencing is a method that determines the order of the four nucleotide bases, namely, adenine (A), thymine (T), guanine (G), and cytosine (C), that form a DNA molecule. In this article, AZoLifeSciences offers a comprehensive guide to DNA Sequencers. Image Credit: Blue Andy/Shutterstock.com In a DNA double helix, nucleotide bases…

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Illumina Complete Long Reads software analysis workflow for human WGS

Introduction Next-generation sequencing (NGS) enables scientists to decipher the genome for a deeper understanding of biology. Proven Illumina sequencing by synthesis (SBS) chemistry combined with award-winning DRAGEN secondary analysis delivers whole-genome sequencing (WGS) data with outstanding accuracy.1,2 DRAGEN Multigenome (graph) further improves mapping accuracy in challenging regions by ~50%.1 Still,…

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High Cost of Advanced Infrastructure for Sequencing Fuels the Sector

DUBLIN, May 29, 2023 /PRNewswire/ — The “Global Microbiome Sequencing Services Market by Service (Sample Preparation, Sequencing, Library Preparation), Type (Amplicon Sequencing, Whole Genome Sequencing), Technology (Sequencing by Synthesis, Nanopore Sequencing), End User – Forecast to 2028” report has been added to  ResearchAndMarkets.com’s offering. The microbiome sequencing services market is projected…

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Global Microbiome Sequencing Services Market Report 2023: High Cost of Advanced Infrastructure for Sequencing Fuels the Sector

DUBLIN, May 29, 2023 /PRNewswire/ — The “Global Microbiome Sequencing Services Market by Service (Sample Preparation, Sequencing, Library Preparation), Type (Amplicon Sequencing, Whole Genome Sequencing), Technology (Sequencing by Synthesis, Nanopore Sequencing), End User – Forecast to 2028” report has been added to  ResearchAndMarkets.com’s offering.   The microbiome sequencing services market is…

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Gene Editing Service Market 2023 Proclaims Tremendous Revenue

Gene Editing Service Market Gene editing is also called genome editing. It is a group of technologies that permit researchers to make a change in the DNA of organisms. Currently, there are several approaches are being developed for gene editing. One of the popular gene editing technologies is the CRISPR-Cas9…

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Increasing Demand for Metagenomic Sequencing Drives Growth

Company Logo Global Microbiome Sequencing Services Market Global Microbiome Sequencing Services Market Dublin, May 29, 2023 (GLOBE NEWSWIRE) — The “Global Microbiome Sequencing Services Market by Service (Sample Preparation, Sequencing, Library Preparation), Type (Amplicon Sequencing, Whole Genome Sequencing), Technology (Sequencing by Synthesis, Nanopore Sequencing), End User – Forecast to 2028”…

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Global Microbiome Sequencing Services Market Report 2023:

Dublin, May 29, 2023 (GLOBE NEWSWIRE) — The “Global Microbiome Sequencing Services Market by Service (Sample Preparation, Sequencing, Library Preparation), Type (Amplicon Sequencing, Whole Genome Sequencing), Technology (Sequencing by Synthesis, Nanopore Sequencing), End User – Forecast to 2028” report has been added to ResearchAndMarkets.com‘s offering. The microbiome sequencing services market…

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NGS-Based RNA-sequencing Markets: Sample Preparation, Platforms & Consumables, Services, Data Analysis, De Novo, Epigenetics, Small RNA

Company Logo Global NGS-Based RNA-Sequencing Market Global NGS-Based RNA-Sequencing Market Dublin, May 26, 2023 (GLOBE NEWSWIRE) — The “NGS-Based RNA-sequencing Market by Product & Services (Sample Preparation, Platforms & Consumables, Services, Data Analysis), Technology (SBS, SMRT, Nanopore), Application (De Novo, Epigenetics, Small RNA), End-User, Region – Global Forecast to 2027”…

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Four MORE Chinese DNA Sequencing Startups

Yesterday I wrote about eight Chinese DNA sequencing companies. Today I found out about 4 more! So let’s very quickly review! Looks like Illumina-style SBS using an unspecified surface amplification approach. According to their website: Q30>85%, run outputs up to 300Gb. Two instruments, the Salus Pro and Salus Evo. Seems…

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Ironwood acquires VectivBio in $1B deal

Ironwood Pharmaceuticals, Inc., a GI-focused healthcare company, and VectivBio Holding AG, a clinical-stage biopharmaceutical company pioneering novel, transformational treatments for severe rare gastrointestinal conditions, have entered into a definitive agreement for Ironwood to acquire VectivBio for $17.00 per share in an all-cash transaction with an estimated aggregate consideration of approximately…

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NGS Sample Preparation Market is expected to advance at a CAGR of 13.7% from 2022 to 2032

[342 Pages Report] The global NGS sample preparation market is expected to be valued at $5441.1 million by 2032, up from $1321.8 million in 2022, and to grow at a 13.7% CAGR during the forecast period (2022-2032). DNA contains the blueprints of life. Within its structures are the codes required for the…

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Sequencing 101: Sequencing coverage – PacBio

 This article explores sequencing coverage fundamentals. Uncover key concepts and discover how highly accurate long-read sequencing provides a comprehensive view of the genome, at any coverage level.  What is sequencing coverage? Genomics professionals use the terms “sequencing coverage” or “sequencing depth” to describe the number of unique sequencing reads that…

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Microbiome Sequencing Services Market Production, Revenue, Price, Trend, Size and Growth Analysis 2032

The Microbiome Sequencing Services Market Size, Scope, and Forecast 2023-2032 report has been added to the Market research collection of Quince Market Insights. Industry experts and researchers have offered an authoritative and concise analysis of the Microbiome Sequencing Services Market with respect to various aspects such as growth factors, challenges, restraints, developments, and opportunities for growth. This…

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The Glue of Genomics: Will Science’s Unsung Data Heroes Abandon Academia?

Advances in the last twenty years of genomics have turbocharged our ability to decode DNA and other nucleic acids. At the turn of the century, the Human Genome Project completed a 13-year journey to produce the first complete human genome at a great financial cost. In 2023, genome sequencing is a routine…

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Difference between variants called in sequences with 2-channel SBS and 4-channel SBS

Difference between variants called in sequences with 2-channel SBS and 4-channel SBS 0 Hi all. I have been using 4-channel SBS for sample sequencing and am considering using 2-channel SBS in the future. I would like to know if there are any papers that discuss the differences in SNPs obtained…

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Genetic immune escape landscape in primary and metastatic cancer

Inference of HLA-I tumor status with LILAC Inference of the correct HLA-I tumor status is fundamental to identifying GIE alterations (Fig. 1a), to estimate the neoepitope repertoire and burden and to predict the response to immune checkpoint inhibitors14,15 (ICIs). We have developed LILAC, a framework that performs HLA-I typing for…

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Clinical Oncology Next-generation Sequencing Market is projected to expand at a prolific CAGR of 16.3% reaching a valuation of US$ 1.14 Billion by 2029

The Clinical Oncology Next-generation Sequencing Market is anticipated to reach US$ 449.4 Million in value by 2022. The total market is anticipated to grow at a remarkable CAGR of 16.3% between 2022 and 2029, reaching a valuation of US$ 1.14 Billion by 2029, due to the increasing implementation of next…

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Jaguar Health : Completes Enrollment in its Pivotal Phase 3 OnTarget Trial of Crofelemer for Prophylaxis of Cancer Therapy-Related Diarrhea – Form 8-K

Jaguar Completes Enrollment in its Pivotal Phase 3 OnTarget Trial of Crofelemer for Prophylaxis of Cancer Therapy-Related Diarrhea Primary endpoint based on patient reported outcomes from study expected in October 2023 With the completion of the PIPE financing of unregistered shares and 6-month lock up term, Jaguar has agreed, as…

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Jaguar Completes Enrollment in Its Pivotal Phase 3 OnTarget Trial of Crofelemer for Prophylaxis of Cancer Therapy-Related Diarrhea

Primary endpoint based on patient reported outcomes from study expected in October 2023 With the completion of the PIPE financing of unregistered shares and 6-month lock up term, Jaguar has agreed, as described below, not to issue additional equity securities before October 22, 2023 – by which point the Company…

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Principal scientist bioinformatics – Urgent Role at Roche in Washington DC

We are looking to hire a resourceful Principal scientist bioinformatics to join our incredible team at Roche in Washington DC.Growing your career as a Full Time Principal scientist bioinformatics is an incredible opportunity to develop excellent skills.If you are strong in presentation, adaptability and have the right mindset for the…

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NGS-based RNA Sequencing Market Expected to Reach USD 19.68 Billion by 2032

Reports And Data The global National-Generation Sequencing (NGS)-based RNA sequencing market size is expected to reach USD 19.68 Billion in 2032 NEW YORK, NY, UNITED STATES, May 2, 2023 /EINPresswire.com/ — The global NGS-Based RNA Sequencing Market sequencing had a value of USD 3.54 Billion in 2022 and is projected…

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NGS Sample Preparation Market is projected to advance at a CAGR of 13.7% from 2022 to 2032 | FMI Study

[342 Pages Report] The global NGS sample preparation market is expected to be valued at $5441.1 million by 2032, up from $1321.8 million in 2022, and to grow at a 13.7% CAGR during the forecast period (2022-2032). DNA contains the blueprints of life. Within its structures are the codes required for the…

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Illumina, under pressure from Icahn, outlines plan to reduce more expenses

By the numbers Q1 Revenue: $1.09 billion 11% decrease year-over-year Q1 Net income: $3 million 96.5% decrease year-over-year Q1 Diluted earnings per share (GAAP): $0.02 96.4% decrease year-over-year Q1 Insights: Illumina, a global leader in DNA sequencing, said it plans to cut costs by $100 million this year as it…

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Global MiRNA sequencing market is expected to register a revenue CAGR of 12% during the Forecast period 2032

Reports And Data The global Micro Ribonucleic Acid (MiRNA) sequencing assay market size is expected to register a revenue CAGR of 12% during the forecast period 2032. NEW YORK, NY, UNITED STATES, April 23, 2023 /EINPresswire.com/ — The Global MiRNA Sequencing Assay Market sequencing assays was valued at USD 594.16…

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NGS Data Analysis Market Sales to Reach US$ 2,314.7 Million by 2032; Rising Demand in Genomics Research Boosts the Growth

PRESS RELEASE Published April 21, 2023 According to Fact.MR, a market research and competitive intelligence provider, the global NGS data analysis market is estimated at US$ 561.4 Million in 2022 and is expected to expand at an impressive CAGR of 15.2% during the forecast years of 2022-2032. The market is…

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VAMOS! Discover hidden VNTRs with long reads

 See how the Chaisson lab created a new method to characterize human VNTR variation with PacBio long-read sequencing.  Structural variants are hard to find with short-read sequencing methods At present, most genomic researchers worldwide use short-read sequencing methods based on aging sequencing-by-synthesis (SBS) technology. However, short reads are unable to…

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