Tag: SEs

r – Clustered standard error bars for two-way bar chart in ggplot

I am looking for help with code for adding clustered standard errors to a two-way bar chart generated using ggplot. All of the packages I find are for regression results. I have data in which 1200 respondents each rated 10 profiles (n=12,000). I want to plot the means (Y) by…

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deeptools.plotCoverage Example

API (Occurances) deeptools.writeBedGraph_bam_and_bw.writeBedGraph(1) deeptools.writeBedGraph.openBam(1) deeptools.writeBedGraph.bedGraphToBigWig(1) deeptools.writeBedGraph.WriteBedGraph(4) deeptools.utilities.toBytes(2) deeptools.utilities.tbitToBamChrName(2) deeptools.utilities.mungeChromosome(2) deeptools.utilities.gtfOptions(1) deeptools.utilities.getTempFileName(8) deeptools.utilities.getGC_content(3) deeptools.utilities.getCommonChrNames(4) deeptools.utilities.bam_total_reads(2) deeptools.plotProfile.main(5) deeptools.plotHeatmap.main(6) deeptools.plotCoverage.main(1) deeptools.parserCommon.heatmapperMatrixArgs(2) deeptools.parserCommon.getParentArgParse(10) deeptools.parserCommon.deepBlueOptionalArgs(1) deeptools.parserCommon.check_float_0_1(1) deeptools.multiBigwigSummary.main(4) deeptools.multiBamSummary.main(2) deeptools.mapReduce.mapReduce(8) deeptools.mapReduce.getUserRegion(3) deeptools.mapReduce.blSubtract(1) deeptools.heatmapper_utilities.plot_single(2) deeptools.heatmapper_utilities.getProfileTicks(2) deeptools.heatmapper.heatmapper(6) deeptools.getScorePerBigWigBin.getScorePerBin(1) deeptools.getScaleFactor.get_scale_factor(1) deeptools.getScaleFactor.get_num_kept_reads(2) deeptools.getFragmentAndReadSize.get_read_and_fragment_length(7) deeptools.deepBlue.isDeepBlue(3) deeptools.countReadsPerBin.CountReadsPerBin(6) deeptools.correlation.Correlation(2) deeptools.computeMatrixOperations.sortMatrix(1) deeptools.computeMatrixOperations.main(5) deeptools.computeMatrix.main(10) deeptools.bigwigCompare.main(2) deeptools.bamHandler.openBam(22) deeptools.bamCoverage.process_args(1) deeptools.bamCoverage.main(9) deeptools.bamCompare.main(7) deeptools.SES_scaleFactor.estimateScaleFactor(2) deeptools.countReadsPerBin.cr.is_proper_pair(1) deeptools.config.config.get(2) deeptools.cfg.config.get(3) Read more…

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Senior Technical Marketing Manager at imperva

SENIOR TECHNICAL MARKETING MANAGER CYBER SECURITY is a big deal. It’s in the news, growing rapidly, a critical tool for every company, and our specialty. Imperva is a public company (NASDAQ) and cybersecurity leader that delivers best-in-class solutions to protect data and applications on-premises, in the cloud, and across hybrid…

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L’essai clinique de Pulsecare Medical sur la technologie nsPFA donne des rsultats satisfaisants de suivi court terme

Class dans : SantSujet : Essais cliniques / Dcouvertes mdicales SHENZHEN (Chine), 31 octobre 2023 /CNW/ – PulsecareMedical, une entreprise innovante de technologie thrapeutique mini-invasive et non invasive, a annonc aujourd’hui que son systme d’ablation en champ puls nanoseconde (nsPFA, nanosecond pulsed field ablation) pour l’lectrophysiologie cardiaque, le premier systme…

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Help Make Biostar Better! Add Your Feedback, Opinions And Suggestions.

News:Help Make Biostar Better! Add Your Feedback, Opinions And Suggestions. 16 Two recent posts made it clear that we don’t have ways to directly collect feedback and suggestions regarding Biostars. As it turns out there are quite a few suggestions that make a lot of sense and are really easy…

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Filgotinib Misses Co-Primary Endpoints in Phase 3 DIVERSITY1 Study, Presented at ACG 2023

Séverine Vermeire, MD, PhD Credit: IBD Leuven Filgotinib did not meet either co-primary endpoint for superior clinical remission or endoscopic response versus placebo in treated patients with moderately to severely active Crohn disease (CD), according to results from the phase 3 DIVERSITY1 study. Presented in an abstract at the American…

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Lilly’s Mirikizumab Helped Patients with Crohn’s Disease Achieve Long-Term Remission in Phase 3 Trial

Mirikizumab demonstrated clinical remission and endoscopic response for patients with moderately to severely active Crohn’s disease through 52 weeks The study achieved the coprimary endpoints and all major secondary endpoints versus placebo This successful Phase 3 trial will be the basis of global regulatory submissions for Crohn’s…

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Whole transcriptome analysis in offspring whose fathers were exposed to a developmental insult: a novel avian model

Werboff, J. & Gottlier, J. S. Drug in pregnancy: Behavioral teratology. Obstet. Gynecol. Surv. 18, 420–423 (1963). Article  Google Scholar  Yanai, J. G. The effect of alcohol consumed by parent mice on the susceptibility to audiogenic seizure and the open-field behavior of their offspring. Behav. Genet. 3, 418 (1973). Google…

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Centers for Disease Control and Prevention hiring Health Scientist (Bioinformatics) in Anchorage, Alaska, United States

DutiesSummaryAs a global leader in public health & health promotion, CDC is the agency Americans trust with their lives. In addition to our everyday work, each CDC employee has a role in supporting public health emergency management, whether through temporary assignments to emergency responses or sustaining other CDC programs and…

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Health Scientist (Bioinformatics) Job in Anchorage, AK

Summary As a global leader in public health & health promotion, CDC is the agency Americans trust with their lives. In addition to our everyday work, each CDC employee has a role in supporting public health emergency management, whether through temporary assignments to emergency responses or sustaining other CDC programs…

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A Novel Therapeutic Target Identified for Pancreatic Ductal Adenocarcinoma

Researchers have identified a novel therapeutic target for pancreatic ductal adenocarcinoma (PDAC), a lethal type of pancreatic cancer. Pancreatic cancer is responsible for over 90% of all cases. Previous studies have not been able to identify the master regulator of cell cycle entry and proliferative metabolism in PDAC. The researchers…

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Neighborhood socioeconomic status is associated with low diversity gut microbiomes and multi-drug resistant microorganism colonization

Buettgens, M., Blavin, F. & Pan, C. The affordable care act reduced income inequality in the US. Health Aff. 40, 121–129 (2021). Article  Google Scholar  Chen, E. & Miller, G. E. Socioeconomic status and health: mediating and moderating factors. Annu. Rev. Clin. Psychol. 9, 723–749 (2013). Article  PubMed  Google Scholar …

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A query about selecting the coefficient in glmLRT to test for by index

A query about selecting the coefficient in glmLRT to test for by index 1 @0b4d0d5b Last seen 9 hours ago Norway I am using the below set of equations for my differential expression analysis. In the glmLRT line, I was previously specifying the coef by index and since I am…

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how to run ROSE to find super enhnacers-

how to run ROSE to find super enhnacers- 1 Hello, I’m pretty new to bioinformatics, and I’m having troubles when trying to run the ROSE package to find SEs. On the website, it’s not clear which files I should bring and what specific file format is required. If someone has…

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A Rationally Designed CRISPR/Cas12a Assay Using a Multimodal Reporter for Various Readouts

journal contribution posted on 2023-07-28, 13:03 authored by Jean de Dieu Habimana, Omar Mukama, Obed Boadi Amissah, Yirong Sun, Eric Karangwa, Yujie Liu, Samson Mugisha, Na Cheng, Ling Wang, Jianlin Chen, Sihao Deng, Rongqi Huang, Zhiyuan Li The CRISPR/Cas systems offer a programmable platform for nucleic acid detection, and CRISPR/Cas-based…

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Global hotspots of traded phylogenetic and functional diversity

Trade data To determine whether a species was traded we used the global terrestrial vertebrate dataset compiled by Scheffers et al.2, filtering for birds and mammals. This contains extensive data from CITES and the International Union for Conservation of Nature (IUCN) red list. The IUCN list was generated via text-string…

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Biomolecules | Free Full-Text | Genome-Wide Acetylation Modification of H3K27ac in Bovine Rumen Cell Following Butyrate Exposure

1. Introduction The digestive tract greatly influences the maintenance of energy requirements in cattle due to its crucial role in digesting and absorbing nutrients. The rumen is an essential organ in the digestive tract for feed efficiency, with relatively high metabolic activities. The digestion of solid-feeding materials generates short-chain fatty…

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Groundbreaking Phase 3 Trial for Revolutionary NSCLC Therapy Gotistobart ONC392BNT316

On June 29, 2023, BioNTech and OncoC4 announced the commencement of a groundbreaking Phase 3 trial for their BNT316/ONC-392 program targeting metastatic non-small cell lung cancer (NSCLC). This trial marks a significant milestone in BioNTech’s strategic plan to initiate multiple pivotal trials throughout 2023 and 2024. The two-stage, open-label, randomized…

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How to merge BLE_UART and Aes_ctr project file – Nordic Q&A – Nordic DevZone

Hello, I have two project one is Ble UART and second AES_ctr, i want to combine AES_ctr project and sdk_config.h file into BLE_UART ,so i can use AES API in BLE UART code can you guide me how to start it. <!DOCTYPE CrossStudio_Project_File> <solution Name=”nrf_crypto_aes_ctr_pca10056″ target=”8″ version=”2″> <project Name=”nrf_crypto_aes_ctr_pca10056″> <configuration …

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Aaron Reams – Software Architect

Aaron Reams Software Architect / Cloud Engineer Raleigh, North Carolina  • 919-987-6141  •  reamer@gmail.com  •  linkedin.com/in/aaronreams •  aaronreams.com  Software Architect & Cloud Engineer with over 20 years of experience using C#, Go, Angular and React developing innovative solutions to complex problems on Amazon Web Services (AWS), Google Cloud (GCP), Microsoft…

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Bioinformatics Engineer II – Hiring Now at Thermo Fisher Scientific in Bangalore

We are on the lookout for a driven Bioinformatics Engineer II to join our exceptional team at Thermo Fisher Scientific in Bangalore.Growing your career as a Full Time Bioinformatics Engineer II is a great opportunity to develop competitive skills.If you are strong in project management, communication and have the right…

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First Oral Medication to Treat Moderate-to-Severe Crohn’s Disease Completes Successful Phase 3 Trial and Earns FDA Approval

“This therapy has the potential to transform the lives of individuals battling this chronic condition and offers a new hope for improved quality of life,” said Jean-Frederic Colombel, MD, co-Director, Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center, The Mount Sinai Hospital. NEW YORK (PRWEB) May 26, 2023 …

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Rinvoq Approved for Moderately to Severely Active Crohn Disease

The Food and Drug Administration (FDA) has approved Rinvoq® (upadacitinib) for the treatment of adults with moderately to severely active Crohn disease who have had an inadequate response or intolerance to 1 or more tumor necrosis factor (TNF) blockers. The approval was based on data from 2 randomized, double-blind, placebo-controlled…

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Does ROSE include traditional enhancer in the analysis output?

Does ROSE include traditional enhancer in the analysis output? 1 Hi, I am doing super enhancer analysis with ROSE. I wonder whether the ROSE software can give the information of traditional enhancers or enhancers that make up SEs. Thanks ROSE Super enhancers • 34 views Yes, pretty much any of…

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sygrna – Korea

SygRNA modified synthetic tracrRNA and crRNAs are optimized for use with a variety of Cas9 expressing cell lines, Cas9 proteins, or Cas9 mRNAs and are …SygRNA® synthetic Francisella novicida tracrRNA complexed with SygRNA® synthetic Francisella novicida crRNA. For use with MISSION® FnCas9 proteins in …16 nov. 2016 — SygRNA™-Synthetic Two Part CRISPR…

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AWS, Google and Microsoft have ignited satcom race, according to DIGITIMES Research

Various satellite projects and applications have been increasingly thriving, which leads to a huge amount of data transmission and processing. Such business opportunities attract cloud juggernauts including Amazon, Microsoft, and Google to justle for the space market. According to DIGITIMES Research, the major public cloud platforms mainly come in three…

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The loss of epigenetic information: not only consequences but a cause of mammalian aging

In a recent study published in Cell, Yang et al. revealed that changes in epigenetic landscapes caused by faithful DNA repair are key drivers accelerating aging of mammalian organs or tissues.1 Impressively, changes in H3K27ac landscape during aging process influence cell identity maintenance, and this aging process can be reversed…

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Moomoo’s Continuous Innovation Journey on AWS

SHENZHEN, China, March 17, 2023 /PRNewswire/ — Moomoo is a financial information and trading app and offers securities services through Moomoo Financial Inc., a U.S. Securities and Exchange Commission (SEC) registered broker. It is regulated by Financial Industry Regulatory Authority (FINRA), a member of the Securities Investor Protection Corporation (SIPC). In…

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sygrna – Bjavkoreannew

SygRNA Cas9 Synthetic Modified tracrRNA; HPLC-purified SygRNA modified tracrRNA oligo is optimized for use with a target-specific crRNA or modified crRNA …The SygRNA™ synthetic RNA system recruits SpCas9 nuclease to specific genomic targets. The tracrRNA (trans-activating crRNA) binds to a crRNA (CRISPR RNA) …16 nov. 2016 — SygRNA™-Synthetic Two Part CRISPR RNA…

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Biologist Bioinformatics Direct Hire Job in ATLANTA, GA

Summary As a global leader in public health & health promotion, CDC is the agency Americans trust with their lives. In addition to our everyday work, each CDC employee has a role in supporting public health emergency management, whether through temporary assignments to emergency responses or sustaining other CDC programs…

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[slurm-users] Slurmd enabled crash with CgroupV2

Hello to all, I’m trying to do an installation of Slurm with cgroupv2 activated. But I’m facing an odd thing : when slurmd is enabled it crash at the next reboot and will never start unless i disable it. Here is a full example of the situation [root@compute…

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bamComparing ChIp-Seq samples with strange coverage between chipped and Input

bamComparing ChIp-Seq samples with strange coverage between chipped and Input 0 I’m having some troubles both estimating the quality and understanding the results of my ChIp-Seq samples as well as to decide how to continue. I hope I can find some help/advice here. I have three conditions, each with duplicates…

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Galapagos NV (GLPG) announces topline results from Phase 3 DIVERSITY trial of filgotinib in Crohn’s disease

News and research before you hear about it on CNBC and others. Claim your 1-week free trial to StreetInsider Premium here. The two induction cohorts missed the co-primary endpoints of clinical remission and endoscopic response at Week 10 In the maintenance phase, filgotinib 200mg once daily achieved the co-primary endpoints…

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Galapagos announces topline results from Phase 3 DIVERSITY

The two induction cohorts missed the co-primary endpoints of clinical remission and endoscopic response at Week 10 In the maintenance phase, filgotinib 200mg once daily achieved the co-primary endpoints of clinical remission and endoscopic response at Week 58 The safety findings were generally consistent with the known profile of filgotinib…

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phylogeny

phylogeny 2 Dear all, I am a student in the field of phylogeny.I calculated the phylogenetic diversity with R Language.I I encountered the above problem.Maybe there’s something wrong with my phylogenetic tree.I wish to ask teachers to help me solve this problem. Thanks a lot!!! Error in node.age(sub.tree) : function…

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Health Scientist Bioinformatics Job in WORLDWIDE

Summary As a global leader in public health & health promotion, CDC is the agency Americans trust with their lives. In addition to our everyday work, each CDC employee has a role in supporting public health emergency management, whether through temporary assignments to emergency responses or sustaining other CDC programs…

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Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations

Study population The study sample included 34,072 unrelated (3rd degree or less) TOPMed participants from eight U.S. based cohort studies: Jackson Heart Study (JHS; n = 2504), Framingham Heart Study (FHS; n = 3520), Hispanic Community Health Study/Study of Latinos (HCHS/SOL; n = 6,408), Atherosclerosis Risk in Communities study (ARIC; n = 6197), Cardiovascular Health Study (CHS; n = 2835),…

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The Identification of Prognostic and Metastatic Alternative Splicing in Skin Cutaneous Melanoma

Skin cutaneous melanoma (SKCM) is a type of highly invasive cancer originated from melanocytes. It is reported that aberrant alternative splicing (AS) plays an important role in the neoplasia and metastasis of many types of cancer. Therefore, we investigated whether ASEs of pre-RNA have such an influence on the prognosis…

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A resource for analysis of variants in human mitochondrial RNAs and DNA

%PDF-1.4 % 38 0 obj > endobj 37 0 obj >stream PScript5.dll Version 5.2.2 2021-12-07T17:12-08:00 2021-12-04T11:46:23-08:00 2021-12-07T17:12-08:00 application/pdf MitoVisualize: A resource for analysis of variants in human mitochondrial RNAs and DNA Administrator Acrobat Distiller 8.1.0 (Windows) uuid:4b3c96da-1dd2-11b2-0a00-a50927fd5800 uuid:4b3c96dd-1dd2-11b2-0a00-6a0000000000 endstream endobj 36 0 obj > endobj 2 0 obj > endobj 1…

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