Hi , im trying to preorm SKAT test (rdrr.io/cran/SKAT/man/SKAT.html) for every gene in my data . in order to do that for every gene i created the genetype matrix which has 21 rows ( as number of patients) and columns as number of SNPs for every gene . this is…

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Full-Time Research Assistant Professor

Position Description The Cruchaga Lab, member of the Neurogenomics and Informatics Center (NGI) at Washington University School of Medicine, invites applications for a faculty position at the rank of Research Assistant Professor to develop a project to identify novel genes and pathways in Alzheimer’s Disease utilizing Whole Genome Sequencing. The…

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Rvtests SKAT-O output

Rvtests SKAT-O output 0 Hi there, After running SKAT-O, the output has some columns that I would like to understand better: NumVar: number of variants in the gene (or site) NumPolyVar: number of Polymorphic Genotypes What’s the difference? Thank you rvtests sequencing SNP • 9 views Login before adding your…

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Rare variant association analysis (SKAT-O)

Hello everyone, I was wondering if it is statistically acceptable to perform SKAT-O analysis one a single gene. To elaborate, I am looking in a miRNA gene (80nt length) and I have found a small number of rare variants present in my case group, but none in my control group….

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