Tag: SPSS

King’s College London hiring Research Associate in Translational Bioinformatics in London, England, United Kingdom

Job DescriptionThis is a Pre-Fellowship for early career researchers wanting to establish a career in MND translational research and become MND research leaders of the future. The postholder will have a leading role in an exciting new project funded by Motor Neurone Disease Association and MND Scotland. The project is…

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csi-miR-96-5p delivered by Clonorchis sinensis extracellular vesicles promotes intrahepatic cholangiocarcinoma proliferation and migration via the ferroptosis-related PTEN/SLC7A11/GPX4 axis | Parasites & Vectors

Human tissue samples The preoperative diagnosis of CS mainly relies on stool microscopy, enzyme-linked immunosorbent assay, or endoscopy. Fresh liver and intrahepatic bile duct specimens were collected from ICC patients with (CS-ICC group) and without (NC-ICC group) CS infection during partial hepatectomy at the First Hospital of Jilin University. Tumor tissues…

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Analysis of sepsis combined with pulmonary infection by mNGS

Introduction Sepsis is one of the major diseases that poses a serious threat to human health, and its incidence and in-hospital mortality rates remain high despite the continuous updating of sepsis guidelines.1 Its main clinical manifestations are elevated body temperature, chills, and rapid heart rate, and it is most common…

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Diagnostic efficacy of mNGS in spinal infection patients

Introduction Spinal infection, an uncommon condition, was first recorded in 1779.1 When the intervertebral disk is infected, it is commonly referred to as spondylodiscitis,2 whereas infection of the vertebral body or endplates is more precisely termed vertebral osteomyelitis or spondylitis.3 The definitive diagnosis of spinal infection is often delayed by…

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Foods | Free Full-Text | Isothermal Amplification and CRISPR/Cas12a-System-Based Assay for Rapid, Sensitive and Visual Detection of Staphylococcus aureus

1. Introduction Staphylococcus aureus [1], one of the top five foodborne pathogens, has a common and strong aggressiveness in humans and can secrete multiple toxic proteins (Pathogenic enterotoxins, Hemolysin, PVL) [1,2] which can cause bacteraemia, endocarditis, meningitis, toxic shock syndrome, pneumonia and other dangerous infectious diseases [3]. Moreover, the worldwide…

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ST23 Klebsiella pneumoniae in China

Introduction Klebsiella pneumoniae (KP), a member of the Enterobacteriaceae family, inhabits aquatic environments and can colonise respiratory and gastrointestinal tracts in humans, making it a significant opportunistic pathogen. It may result in pneumonia, meningitis, urinary tract infections, and bloodstream infections. Hypervirulent Kp (HvKp) is believed to cause severe community-acquired invasive…

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Endometrial cancer PDX-derived organoids (PDXOs) and PDXs with FGFR2c isoform expression are sensitive to FGFR inhibition

Patients, tumour Implantation, PDX expansion and characterization The study was conducted according to the Declaration of Helsinki. Tumours were collected from EC patients following Human Research Ethics Committee (HREC) approval (HREC/15/MHS/127) and QUT HREC (#1500000169, 1500000323). All participants provided written informed consent that their excess tissue could be used for…

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Correlation Between the Levels of ANGPTL3, ANGPTL4, ANGPTL8 and Postpr

Introduction As the prevalence of hyperlipidemia has increased, the assessment of blood lipids is increasingly important.1 At present, fasting lipid indices, including total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C) levels are most commonly assessed in clinical practice.2 Among them, the TG level is one of the most…

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Key Genes for Pyroptosis-induced Salivary Gland Inflammation

Kaiyuan Zhang,1,* Ziyue Luo,1,* Xinchao Zhu,1 Xinyi Yao,1 Dingqi Lu,2 Liying Chen,1 Tao Hong,1 Yating Ren,1 Xinchang Wang3 1Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310053, People’s Republic of China; 2First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310053, People’s Republic of China;…

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NOTCH1 mutations predict superior outcomes, NSCLC

Introduction Lung cancer remains the leading cause of cancer-related mortality worldwide, and the majority are non-small-cell lung cancer (NSCLC).1,2 Genetic variation is a typical feature of NSCLC that drives cancer initiation and progression.3 Understanding the role of mutated genes in NSCLC is the basis of the development of novel treatment…

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Learn Rstudio Ide: Quick, Effective, and Productive Data Science (Paperback)

$37.99 Usually Ships in 1-5 Days Description Discover how to use the popular RStudio IDE as a professional tool that includes code refactoring support, debugging, and Git version control integration. This book gives you a tour of RStudio and shows you how it helps you do exploratory data analysis; build…

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RStudio For Quantitative Finance

Introduction to RStudio R is widely used in quantitative finance due to its extensive statistical capabilities, data manipulation tools, and its active community that develops and maintains specialized packages for finance. It offers a wide range of functionalities that enable professionals in the finance industry to analyze data, build models,…

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How To Read Data In R

Source: Ytimg.com Are you interested in analyzing and extracting insights from data using R? If so, learning how to read data in R is a fundamental skill that will empower you to explore and manipulate datasets effectively. R, a powerful programming language and software environment for statistical computing, provides various…

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High sensitivity and specificity in fetal gender identification in the first trimester, using ultrasound and Noninvasive Prenatal Screening (NIPS) in twin pregnancies, a prospective study | BMC Pregnancy and Childbirth

This was a prospective study; we included all pregnant women aged eighteen and over, carrying two live fetuses with CRL that was measured between 45 -84 mm. All women gave their written informed consent. Excluded were women with triplet pregnancies that were reduced to twins, and cases of vanished twin. Women…

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COL10A1 promotes tumorigenesis by modulating CD276 in pancreatic adenocarcinoma | BMC Gastroenterology

Bioinformatics analysis The GEO database (www.ncbi.nlm.nih.gov/geo/) provided detailed gene expression information for the GSE62165 microarray. Differentially expressed genes were identified using the online tool Morpheus (software.broadinstitute.org/morpheus/) (fold change = normal pancreatic tissue gene expression/PDAC tissue gene expression, P value < 0.05 and |log2(fold change)|>1). The downstream analysis was based on the genes with the…

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Detection of Clostridium perfringens Using Novel Methods Based on Recombinase-Aided Amplification Assay-Assisted CRISPR/Cas12a System

Clostridium perfringens is a highly versatile pathogen of humans and animals. Rapid and sensitive detection methods for C. perfringens are urgently needed for the timely implementation of control. In this study, to provide novel promising methods for the detection of C. perfringens, two rapid, sensitive, and instrument-free C. perfringens detection…

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Research Assistant (Renal Immunology & Genetics – Paediatrics) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The National University of Singapore invites applications for Research Assistant in the Renal Immunology & Genetics (IMM-RIG) division, Department of Paediatrics, Yong Loo Lin School of Medicine. Our research studies comprise both clinical and laboratory-based research with the aim to better understand the type of kidney diseases that affect…

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Fonsecaea monophora causing cerebral phaeohyphomycosis

Introduction Phaeohyphomycosis (PHM) is a group of superficial and deep mycoses, including central nervous system (CNS) infections, pulmonary infections, cutaneous and subcutaneous infections, associated with high mortality and caused by dematiaceous fungi that have brown-pigmented cell walls due to the formation of melanin.1,2 Previously, fungal brain infections generally occurred in…

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BDQ resistance and molecular characterization of RR-TB

Enyu Tong,1,&ast; Ying Zhou,1,&ast; Zhengwei Liu,2 Yelei Zhu,2 Mingwu Zhang,2 Kunyang Wu,2 Junhang Pan,2 Jianmin Jiang1– 3 1School of Public Health, Hangzhou Normal University, Hangzhou, 311100, People’s Republic of China; 2Tuberculosis Control Department, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, 310051, People’s Republic of China; 3Key Laboratory of…

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bioinformatics | Freelancer

I am looking for a freelancer who can assist me with a bioinformatics project. Specifically, I need help with the following tasks: – Data analysis: I require a comprehensive statistical, functional, and integrative analysis of microbiome data. – Sequence alignment: I need assistance with genome annotation and sequence alignment. –…

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Datenauswertung Statistik Beratung R Studio SPS…

Hey, Als Masterand der klinischen Psychologie und Psychotherapie mit durchweg sehr guten Leistungen, sowie herausragenden Leistungen in den empirischen Forschungsmethoden und Statistik, sowie langjähriger und diverser Berufserfahrung in der Forschung als auch Beratung in allen Angelegenheiten empirischer Forschungsarbeiten berate ich Dich gerne kostengünstig bei allen Themen rund um die empirische…

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PLA2G7 gene polymorphism in gestational diabetes mellitus

Introduction Gestational diabetes mellitus (GDM) is a general term for abnormal glucose tolerance, abnormal fasting blood glucose, and diabetes detected or developed during pregnancy, excluding diabetes that already existed before pregnancy. According to the International Diabetes Federation, the global prevalence of GDM in 2021 was approximately 16.7% and has become…

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Clinical characteristics of severe COVID-19 patients

Introduction Coronavirus disease 2019 (COVID-19) first broke out in Wuhan, China, in December 2019. Subsequently, COVID-19 spread rapidly and widely, causing a pandemic.1 It has emerged as a well-known human pandemic over the last three years due to its high pathogenicity and infectivity, which posed serious risks to public health.2…

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What is the difference between R and SPSS in estimating random effects? – rstudio

Hello,I need to estimate a generalized linear mixed model (GLMM).When using R, I need to choose a specific fixed effect (one of the independent variables in the model) to have a random slope according to a random variable such as subject ID.But when using SPSS, I can’t choose a specific…

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To genetically characterize Fasciola adult worms

Introduction Fascioliasis is a zoonotic disease of public health significance and a worldwide distribution.1 The causative agents of Fascioliasis are F. hepatica (F. hepatica; temperate liver fluke) and Fasciola gigantica (tropical liver fluke).2,3 Although it has been recognized for centuries, the disease is currently expanding and has a serious impact…

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A new method for the detection of Mycobacterium tuberculosis based on the CRISPR/Cas system | BMC Infectious Diseases

Expression and purification of Cas12a protein The pMBP-LbCas12a recombinant plasmid used in this study was purchased from Addgene Global Plasmid Information Sharing Platform (Plasmid#113,431) and was 9653 bp in size. The recombinant plasmid was transformed into DH5α competent state and cultured at 37℃ for 6 h. IPTG was added at a final…

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Exercise 2: Skin color by gender of various Star Wars

Exercise 2: Skin color by gender of various Star Wars character species The following graph comes from the starwars dataset. ggplot(starwars, aes(x=species, y=stat(count), fill=skin_color)) + geom_bar() + facet_wrap(~gender)+ coord_flip() + theme(legend.position=”bottom”) Below is a contingency table of species and gender (but not skin color). The percentages down the columns add…

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Bioinformatics/Biostatistics Specialist in Ithaca, NY for Cornell University

Details Posted: 11-Oct-23 Location: Ithaca, New York Type: Full-time Salary: Open Categories: Staff/Administrative Bioinformatics/Biostatistics Specialist Bioinformatics/Biostatistics Specialist: Statistician II The Division of Nutritional Sciences (the Division) plays a leading role in national and international nutrition research, teaching, and public engagement. Focal areas for faculty research include precision nutrition, metabolism, lifecycle…

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Comparative analysis using Rstudio of bluechip stocks

I am looking for a freelancer who can perform a comparative analysis of bluechip stocks using Rstudio. The purpose of the analysis is to analyze the performance of bluechip stocks over the past year. Skills and Experience: – Proficiency in Rstudio and data analysis – Experience in performing comparative analysis…

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Diabetic Foot Ulcer and the Bacterial Colony of the Skin

Introduction Diabetes is a growing public health problem with increasing prevalence and mortality that threatens the health of people globally.1 In 2021, the global prevalence of diabetes in adults aged 20 to 79 years was estimated at 537 million, mainly caused by type 2 diabetes, and the number is expected…

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The Clinical Impact of mNGS for the Diagnosis of PJI

Introduction The total number of periprosthetic joint infection cases is increasing with the surging numbers of joint arthroplasties, internal fixation implantation and the use of immunosuppressive agents.1,2 Unfortunately, the identification of corresponding pathogens remains time-consuming and challenging because of inert bacteria, biofilm formation and prior antibiotic administration.3–8 Metagenomic next-generation sequencing…

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Secondary infection surveillance | IDR

Introduction The coronavirus disease 2019 (COVID-19) caused by the emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continues to threaten human life worldwide. The disease severity of COVID-19 patients is very wide: from an asymptomatic carrier state to severe infection and critical illness with intensive care admission and/or mechanical…

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Establishment and Performance Evaluation of Multiplex PCR-Dipstick DNA Chromatography for Mycoplasma pneumoniae and Chlamydia pneumoniae Rapid Detection

Background and Objective. Mycoplasma pneumoniae (MP) and Chlamydia pneumoniae (CP) infections are becoming increasingly prominent in respiratory infections. This study established a rapid, simple, sensitive, accurate multiplex PCR-dipstick DNA chromatography assay for Mycoplasma pneumoniae and Chlamydia pneumoniae detection. Methods. Nasopharyngeal swab samples of 300 children with an acute respiratory tract…

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The 16 Best Enterprise Data Science Software & ML Tools for 2023

Solutions Review’s listing of the best enterprise data science software and machine learning tools is an annual sneak peek of the top tools included in our Buyer’s Guide for Data Science and Machine Learning Platforms. Information was gathered via online materials and reports, conversations with vendor representatives, and examinations of…

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Change size of printed R ggplot in SPSS output

Hi there!  I am trying to use ‘BEGIN PROGRAM R / END PROGRAM’ to run a ggplot within SPSS (specifically, a clustered bar plot).  The syntax seems to be working well overall – except that I want the legend to be to the right of the plot while still being…

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Research Assistant (Breast Cancer Screening and Prevention Programme) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The appointee will be part of the team conducting the ‘Breast Cancer Screening and Prevention Programme’ under Yong Loo Lin School of Medicine; assisting Principal Investigator, Co-investigator and Program Manager in the building and expanding of the current database for research on breast cancer and screening. Primary Responsibilities…

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Diagnostic value and clinical application of mNGS

Introduction Infection is one of the greatest challenges for critically ill patients and intensivists. Previous investigations reported that 30% to 60% of antimicrobials used in ICUs are unnecessary, inappropriate, or suboptimal,1,2 which might be partly attributed to the many defects of conventional microbiological tests (CMT). Culture is the most commonly…

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Research Associate (Breast Cancer Screening and Prevention Programme) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The appointee will be part of the team conducting the ‘Breast Cancer Screening and Prevention Programme’ under Yong Loo Lin School of Medicine; assisting Principal Investigator, Co-investigator and Program Manager in the building and expanding of the current database for research on breast cancer and screening. Primary Responsibilities…

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Rapid Detection of blaKPC in Carbapenem-Resistant Enterobacterales Based on CRISPR/Cas13a

Materials and Instruments Clinical Strains and Sputum Samples Collection A total of 117 bacterial strains were isolated and collected from sputum samples of individual patients with suspected intestinal infection treated at our hospital during the first half of 2021. Carbapenemase production was confirmed by the Modified Carbapenem Inactivation Method (mCIM)…

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Career Associated – Kenya Medical Research – KEMRI – Biostistician/Bioinformatics

All jobs > Research > Kenya Medical Research – KEMRI – Biostistician/Bioinformatics – DLSP Kenya Medical Research – KEMRI Get a free C.V. review by sending your C.V. to submitcv@careerassociated.com or click the following link. Submit C.V.! use the subject heading REVIEW. IMPORTANT: Read the application instructions keenly, Never pay for a…

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ncRNA | Free Full-Text | Long Non-Coding RNA TUG1 Gene Polymorphism and TUG1 Expression Level as Molecular Biomarkers of Systemic Lupus Erythematosus and Lupus Nephritis

1. Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide variety of manifestations ranging from mild cutaneous to organ failure as lupus nephritis (LN) and cardiopulmonary complications [1]. SLE is mainly present among young women, with a greater incidence in certain ethnic groups, such as Asian,…

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Metagenomic next-generation sequencing in CNS cryptococcosis

Introduction Central nervous system (CNS) cryptococcosis is an invasive fungal infection caused by Cryptococcus spp. Although the infection is preventable and treatable, its morbidity and mortality rates are still high.1 Global cryptococcal meningitis accounts for 15% of acquired immune deficiency syndrome-related deaths, with an estimated 181,100 deaths annually.2 In the…

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Research Assistant (Drug Discovery & Optimization Platform) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The National University of Singapore invites applications for a Research Assistant position in the Drug Discovery & Optimization Platform (DDOP), Yong Loo Lin School of Medicine. DDOP focuses on drug screening technology development, molecule chemical modification and optimization, and drug screening services. Appointments will be made on a ONE YEAR contract basis, with the possibility of…

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Analyze your research data with spss, rstudio, stata, or python by Hayden_border

Greetings, esteemed client; I express my sincerest gratitude to you for selecting my services and taking the time to peruse my gig. I am Hayden, a proficient researcher, and certified data analyst by IBM. I am proficient in manipulating data using various software like Python, Stata, R studio, and SPSS,…

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AQFI251- Introduction TO R Studio – Welcome to the first AQFI251 R session! Tutorial aims:

AQFI251 – INTRODUCTION TO R STUDIO Welcome to the first AQFI251 R session! Tutorial aims: 1. Understand what are R and RStudio 2. Develop the good habit of working with scripts Steps: 1. Download R and RStudio 2. Undertake simple commands 3. Glossary In our first session, we will start…

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Clinical efficiency of mNGS in sputum for pathogen detection

Introduction Lower respiratory infections (LRIs) are the world’s most deadly communicable disease and ranks fourth as the primary cause of death globally according to the World Health Organization (WHO) 2019 report.1,2 LRIs include hospital-acquired pneumonia (HAP), community-acquired pneumonia (CAP), bronchiolitis, bronchitis, and tracheitis.3,4 Immunocompromised patients have a higher risk of…

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Molecular detection and characterization of SARS-CoV-2 in cats and dogs of positive owners during the first COVID-19 wave in Brazil

Study design This was an observational study conducted between October 2020 and June 2021 in five large metropolitan areas in Brazil, belonging to four of the five different Brazilian geographical regions (Recife, Belo Horizonte, São Paulo, Campo Grande and Curitiba). Dogs and cats whose owners tested positive for SARS-CoV-2 by…

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KRTA6A and FA2H Are Hub Genes Associated With Cgas-STING-related Immunogenic Cell Death in Lung Adenocarcinoma

Abstract Background/Aim: The immunogenic cell death (ICD) pathway plays a crucial prognostic role in lung adenocarcinoma (LUAD) therapy. The cyclic GMP–AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is an upstream mechanism that drives ICD activation, but the interaction of hub genes remains unclear. The present study aimed to investigate…

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Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells

Directed differentiation of hiPSCs (SBAD2) towards cardiomyocytes after exposure to teratogens and non-teratogens To study the early events of the process of cardiomyogenesis, we used a cell monolayer-based directed hiPSC differentiation protocol, designated as the UKK2 cardiotoxicity test (UKK2-CTT), which is based on the sequential activation and inhibition of Wnt/β-catenin…

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A G1528C Hadha knock-in mouse model recapitulates aspects of human clinical phenotypes for long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency

All animal procedures were reviewed and approved by the OHSU IACUC (eIACUC #B11243). All experiments were performed in accordance with AAALAC and ARRIVE guidelines. Age, sex, and N of the mice for each experiment can be found in Supplementary Data 1. Mouse creation Mice were created through Cyagen Biosciences (Santa Clara,…

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Moderation Analysis, Manual Points for Visualization – RStudio IDE

Hi Everyone, I am more familiar with the Hayes Process app on SPSS and have been trying to make the switch to R, with SPSS Hayes it gives you data points to transfer into a program such as excel to create a graph. It is titled Data for visualizing conditional…

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Clinical Value of Sampling Time of mNGS

Introduction Severe pneumonia is associated with high morbidity and mortality, especially in the ICU, and is one of the global burdens of infectious diseases.1,2 For patients with severe pneumonia, rapid identification of pathogens and timely initiation of appropriate anti-infective therapy are the most critical determinants of prognosis. Furthermore, pathogen diagnosis…

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Use of bioinformatics in genome research in Saudi Arabia

Background Bioinformatics is a new discipline that merges biology, computer science, and information technology. It involves developing and integrating techniques, such as applied mathematics, statistics, computer science, chemistry, and biochemistry, to solve biological problems. Bioinformatics researchers develop and use computing tools to gain more about the life and survival of…

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Measure quantity of mitochondrial DNA in aged bones or calculate it from nuclear DNA quantitative PCR results?

Sample selection Samples from two mass gravesites located near one another and dating back to the Second World War were selected because of their challenging yet relevant characteristics in forensic genetic examinations (skeletonized human remains, long postmortem interval, and DNA degradation). The samples were the diaphyses of femurs, cut below…

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Clinical Evaluation of Metagenomic Next-Generation Sequencing and Iden

Introduction Infection is one of the major causes of death in patients with acute and critical illnesses. Especially, lower respiratory tract infections (LRTIs) are the most common infectious diseases worldwide, with a high mortality rate.1,2 As estimated, there are about 10 million new cases of LRTIs in China each year.3,4…

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ClearanceJobs hiring Bioinformatics Engineer with Security Clearance in Atlanta, Georgia, United States

In this age of disruption, organizations need to navigate the future with confidence by tapping into the power of data analytics, robotics, and cognitive technologies such as Artificial Intelligence (AI). Our Strategy & Analytics portfolio helps clients leverage rigorous analytical capabilities and a pragmatic mindset to solve the most complex…

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Hemoglobin O-Arab first-time molecular detection

Introduction Sickle Cell Disease (SCD) Sickle cell disease is an inherited chronic hemolytic anemia whose clinical manifestations arise from the tendency of the hemoglobin (HbS or sickle hemoglobin) to polymerize and deform red blood cells into the characteristic sickle shape.1 Hb S is insoluble and crystallizes in environments with minimal…

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Whole genomic analysis of Mycobacterium tuberculosis

Introduction Tuberculosis (TB), caused by etiological Mycobacterium tuberculosis (Mtb), remains a public health worldwide and the leading cause of death from a single infectious agent until the COVID-19 pandemic.1 Previous studies revealed that M. tuberculosis originated in Africa and spread with human migration worldwide, it developed to a contemporary phylogeny…

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Skills needed to pursue a career in Biotechnology

The study of the natural world in all its glory is inherently a gigantic, and sometimes overwhelming, field. Consider even a small slice of this large metaphorical cake – biotechnology as a field is large, varied, and ever-growing. In essence, biotechnology focuses on making use of research to develop new…

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Do biostatistics analysis with spss rstudio stata minitab by Betty_tutor

Hello, I specialize in various aspects of biostatistics, including but not limited to: Experimental Design Statistical Analysis of Clinical Trials Epidemiological Studies Data Cleaning and Preprocessing Regression Analysis Data Visualization Sample Size Determination Survival Analysis Meta-Analysis I offer a wide range of biostatistical services, such as: Designing robust study methodologies…

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integrated development environment (IDE) for R (Free software)

RStudio is the integrated development environment (IDE) for R programming language, It was built to ease and automate the workflow of R with a user-friendly interface. Many people are not comfortable working with terminals, RStudio was built to make R easier for them. It has a built-in package manager, session…

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Open Source Mathematical Software (Free app)

SageMath is a free open-source mathematics software system licensed under the GPL. It builds on top of many existing open-source packages: NumPy, SciPy, matplotlib, Sympy, Maxima, GAP, FLINT, R and many more. Access their combined power through a common, Python-based language or directly via interfaces or wrappers. Mission Creating a…

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Research Associate (Allergy & Immunology – Paediatrics) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The Division of Allergy & Immunology at the Department of Paediatrics, Yong Loo Lin School of Medicine, NUS is looking for highly motivated and enthusiastic candidates with a keen interest in clinical translational research in allergic disease epidemiology and pathophysiology to join our team as a Research Associate….

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Microorganisms | Free Full-Text | Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates from Diabetic and Non-Diabetic Patients with Pulmonary Tuberculosis

1. Introduction Globally, about 10 million people are estimated to have developed tuberculosis (TB) in 2020 with eight countries accounting for two-thirds of the global total, with India reporting the largest proportion at 26% [1]. Type 2 diabetes mellitus (DM) is becoming a major public health problem globally, especially in…

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Vascular level inflammatory response induced by COVID-19

Runlong Lin,1,2 Jing Yu,2 Aijuan Tian,2 Xiaomei Wang,2 Xin Yuan,2 Wengui Xu,1 Wenli Xie3 1Department of Molecular Imaging and Nuclear Medicine, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin, People’s…

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Proviral HIV-1 DNA Genotyping for People Living with HIV

Introduction Antiretroviral therapy (ART) can effectively suppress HIV-1 replication and maintain plasma viral load (VL) below the detection limit for most of the people living with HIV (PLWH) who adhere to the regimens prescribed,1 which helps reduce morbidity, mortality, and HIV-1 transmission, and consequently result in improving life expectancy of PLWH. However,…

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Squamata reptiles as a potential source of helminth infections when preyed on by companion animals | Parasites & Vectors

Bomford M, Kraus F, Barry SC, Lawrence E. Predicting establishment success for alien reptiles and amphibians: a role for climate matching. Biol Invasions. 2009;11:713–24. Article  Google Scholar  Shaw GH. End of Cretaceous extinction: the end of the dinosaurs. In: Shaw GH, editor. Great moments in the history of life. Cham:…

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Institutes offers Data Science Course with Placement Assistance

Top 5 Institutes that offers Data Science Course with Placement Assistance Data science is revolutionizing industries and transforming decision-making processes. With India’s rapid technological advancement and its thriving IT sector, the demand for skilled data scientists has skyrocketed. As a result, numerous data science courses have sprouted across the country….

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Neutrophil extracellular traps predict postoperative pulmonary complications in paediatric patients undergoing parental liver transplantation | BMC Gastroenterology

Study design and subjects This prospective study was conducted at Renji Hospital, School of Medicine, Shanghai Jiaotong University from July 1, 2019, to October 10, 2020. The study protocol was approved by the Renji Hospital Ethics Committee and adhered to the principles of the Declaration of Helsinki. Written informed consent…

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Circular RNA RSU1 promotes retinal vascular dysfunction by regulating miR-345-3p/TAZ

Patients and samples A total of 103 diabetes mellitus (type 2) patients were recruited according to the criteria from the American Diabetes Association30. Plasma samples were collected from blood of all the patients, and the patients were classified as diabetes mellitus patients without DR (n = 53) and diabetes mellitus patients with…

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DATA SCIENCE MACHINE LEARNING RSTUDIO R PROGRAMMING LINUX | Classes & Lessons | Edmonton

We are a team of IT Professionals having years of experience in developing Software Related Projects. Over these years, we have completed many individual and industrial level projects and can code any program of C, Cpp, Python, Java and C Sharp including GUI tasks. We will code C, C++, Java,…

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Novel and Validated Inflammation-Based Prognosis Score

Introduction Diffuse large B-cell lymphoma (DLBCL) is a group of B cell-derived malignant tumors with obvious heterogeneity.1 After obtaining standardized treatment, a sizeable portion of DLBCL patients can be cured and survive for a long time. However, roughly one-third of DLBCL patients experience drug resistance and disease recurrence.2,3 Therefore, it…

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mNGS to detect pathogens in children with pneumonia

Introduction Pulmonary infection is one of the most common diseases of the respiratory system, and severe infections in patients with underlying diseases are associated with a high mortality rate and substantial damage to human health. The rate of detecting bacteria and fungi by traditional culture is 21.7%.1 Identifying pathogenic bacteria…

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Mann Whitney U Test with Rstudio: A Comprehensive Guide

Introduction A statistical technique used to assess if there is a significant difference in the distributions of two independent groups is the Mann-Whitney U test, commonly referred to as the Mann-Whitney-Wilcoxon test. Unlike parametric tests, the Mann-Whitney U test is appropriate for non-normal data since it does not require that…

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CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process

General Lab Operation The assays were performed by experienced individuals throughout the course of the study. The study was performed using established laboratory protocols covering the processing, freezing, storage and thawing of cells as well as the staining procedure, data acquisition and gating strategy. Additional data beyond the data found…

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Agronomy | Free Full-Text | Construction and Functional Evaluation of CRISPR/Cas9 Multiple Knockout Vectors of the FAD2 Gene Family

1. Introduction Soybean (Glycine max (Linn.) Merr.) originated from China and is one of the most important legume and oil crops in the world [1]. The index evaluation of soybean oil is mainly related to the content and composition ratios of five fatty acids: oleic acid (C18:1), linoleic acid (C18:2),…

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Integrated bioinformatics and wet-lab analysis revealed cell adhesion prominent genes CDC42, TAGLN and GSN as prognostic biomarkers in colonic-polyp lesions

Clinicopathological characteristics of patients with pre-cancerous lesions Clinicopathological features of the 20 included patients with colon polyps were extracted from their files and presented at the beginning of the survey. All resected samples were categorized into high-risk and low-risk polyps based on reported pathological feature of the samples. The mean…

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Diagnostic performance of mNGS in identification of NTMPD

Introduction Non-tuberculous mycobacteria (NTM) is a collective name given to a group of more than 190 species of Mycobacterium other than Mycobacterium tuberculosis and Mycobacterium leprae.1 NTM are labeled as environmental mycobacteria as they are widely distributed in the environment, such as in soil, marshland, streams, rivers, estuaries, dust, domestic…

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Research Fellow, Bioinformatician job with UNIVERSITY OF WESTERN AUSTRALIA

Medical School Opportunity for an experienced Bioinformatician to join a collaborative team and work on developing “systems genetics” technology. Level B, full-time appointment on a fixed term basis for 12 months Base salary range: $105,043 – $124,301 p.a. plus 17% superannuation The University of Western Australia…

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Principal RWE Research Analyst (Bioinformatics) – Start Immediately at Conexts in Dublin

We are looking to hire a confident Principal RWE Research Analyst (Bioinformatics) to join our passionate team at CONEXTS in Dublin.Growing your career as a Full Time Principal RWE Research Analyst (Bioinformatics) is a great opportunity to develop competitive skills.If you are strong in leadership, creativity and have the right…

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Nitrate and a nitrate-reducing Rothia aeria strain as potential prebiotic or synbiotic treatments for periodontitis

Bacterial strains and growth conditions Rothia aeria CECT9999 (Ra9, isolate D1P7 described in24), was used as a nitrate-reducing probiotic candidate. Prior to the experiment, Brain Heart Infusion (BHI) (Biolife, Deerfield, Illinois, USA) agar plates were inoculated with the strain, incubated for 48 h at 37 °C, and stored at 4 °C for up…

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Combination of CEACAM5, EpCAM and CK19 gene expressions in mediastinal lymph node micrometastasis is a prognostic factor for non-small cell lung cancer | Journal of Cardiothoracic Surgery

Patients From July 2013 through July 2014, 32 consecutive patients with operable NSCLC, according to NCCN guidelines stage 2B and/or lower, and with no prior neoadjuvant treatment regimens were enrolled in the study. Before the operation, every patient underwent a positron emission tomography (PET) scan and brain magnetic resonance imaging…

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Comparison of pathogen detection consistency between metagenomic next-generation sequencing and blood culture in patients with suspected bloodstream infection

Study subjects We retrospectively studied patients with suspected bloodstream infection admitted to the emergency department of Ruijin Hospital from January 2020 to June 2022. The inclusion criteria were as follows: all patients were ≥ 16 years old and meanwhile, had a maximum body temperature higher than 38.5 °C, chills, and antibiotic use for more…

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Administration Guide – R Package Dependencies

The following is a list of all of the R packages RStudio depends on in some way. None of these packages are necessary for the basic operation of RStudio; they all enable additional IDE functionality as noted in in Features. This information is also available in the IDE itself using…

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Comparison and fusion prediction model for lung adenocarcinoma with micropapillary and solid pattern using clinicoradiographic, radiomics and deep learning features

Patients This respective multicohort study was approved by the Institutional Review Board of The First Affiliated Hospital of Nanjing Medical University (Permit Number: 2021-SRFA-238) and the Institutional Review Board of the Affiliated Huaian NO.1 People’s Hospital of Nanjing Medical University (Permit Number: 2022-0451-01), respectively. And the requirement of written informed consent…

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Association between ANGPTL3, 4, 8 and CVRF in HTN

Fangfang Xu,1,&ast; Lijun Shen,2,&ast; Yongguang Yang,2 Limin Kong,3 Wufan Zu,4 Dandan Tian,5 Xuanchao Cao,1 Gairong Huang1 1Key Laboratory of Geriatrics, Institute of Geriatrics, Department of Geriatric Medicine, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China; 2Department of Clinical Medical Research Center, Henan Provincial People’s…

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how to export data from rstudio to excel

You need to write the path of the file in the function drop_delete(), We can summarize all the functions in the table below, Copyright – Guru99 2023 Privacy Policy|Affiliate Disclaimer|ToS, How to Export a DataFrame to a CSV File in R, How to Export a Data from R to Excel…

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MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways

Cell lines Human melanoma cell lines (A375 and A875) were kindly donated by the Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology. Cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM) supplemented with 10% FBS, 100 μg/ml penicillin and 100 μg/ml streptomycin at 37 °C in a…

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Human bone marrow-derived mesenchymal stem overexpressing microRNA-124-3p inhibit DLBCL progression by downregulating the NFATc1/cMYC pathway | Stem Cell Research & Therapy

Microarray-based expression analysis and GEO database analysis The DLBCL-related miRNA expression profiles of GSE29493 and GSE40239 were retrieved from the Gene Expression Omnibus (GEO) database (www.ncbi.nlm.nih.gov/geo/). MiR-124’s pan cancer analysis is conducted through online websites (www.picb.ac.cn/dbDEMC/). Bioinformatics predicted NFATc1 as the target of miR-124-3p The miRbase (www.mirbase.org/), miRDB (mirdb.org), and…

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Value of mNGS for rapid diagnosis of spinal tuberculosis

Introduction Mycobacterium tuberculosis (MTB) infection in humans leading to tuberculosis (TB), which is an ancient infectious disease that threatens public health.1 TB can be categorized as extrapulmonary TB (EPTB) or pulmonary TB according to the status of MTB infection in the lungs.2 Notably, EPTB is the collective term for all…

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Alterations of mtDNA copy number and 4977 bp deletion induced by ionizing radiation in human peripheral blood

Alterations of mtDNA copy number and 4977 bp deletion induced by ionizing radiation in human peripheral blood 2 first-author 1 1 1 3 1 1 3 corresp Corresponding author. E-mail address: lym636160@sina.com Corresponding author. E-mail address: lym636160@sina.com lym636160@sina.com Henan Institute of Occupational Medicine, Zhengzhou 450052, China Henan Institute of Occupational…

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Intro to R and RStudio (beginner)

Is R the right tool for your data analysis needs? 1. A software for statistical computing and graphics R vs other statistical software such as SPSS, SAS, STATA, Mplus, HLM etc. : Pros Accessibility: R is free and open-source, while other statistical software like SPSS is proprietary software that requires…

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Scholarships and Career Opportunities: Postdoctoral in bioinformatics

Description of the workplaceThe Cardiovascular research – Translational studies is studying cardiovascular disease with a focus on biological differences that underlie acute complications such as heart attacks and strokes. The research is translational and includes studies of human tissue and several in-vitro models. The group has for many years been…

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Pathogen Diagnosis Value of Nanopore Sequencing

Introduction Severe hospital-acquired pneumonia (SHAP) is the most common acquired infection in the intensive care unit (ICU) and one of the main causes of increased mortality in ICU patients.1,2 Potential multidrug-resistant pathogens are very common in ICU-acquired pneumonia, including Pseudomonas aeruginosa, Acinetobacter spp., methicillin-resistant Staphylococcus aureus (MRSA), and ultrabroad spectrum…

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BRAFV600E, BRAFK601E, NRAS, HRAS, and KRAS mutational status

Agnes Stephanie Harahap,1– 3 Imam Subekti,4 Sonar Soni Panigoro,5 Asmarinah,6 Lisnawati,1 Retno Asti Werdhani,7 Hasrayati Agustina,8 Dina Khoirunnisa,1 Mutiah Mutmainnah,1 Salinah,1 Alvita Dewi Siswoyo,9 Maria Francisca Ham1,2 1Department of Anatomical Pathology, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; 2Human Cancer Research Center-Indonesian Medical Education and Research Institute,…

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Postdoctoral in bioinformatics – Academic Positions

Lund University, Faculty of Medicine, Department of Clinical Sciences, Malmö Description of the workplaceThe Cardiovascular research – Translational studies is studying cardiovascular disease with a focus on biological differences that underlie acute complications such as heart attacks and strokes. The research is translational and includes studies of human tissue and…

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Pinostrobin, a fingerroot compound, regulates miR-181b-5p and induces acute leukemic cell apoptosis

Leukemia cell culture The human acute promyelocytic leukemia cell line (NB4) and the human acute lymphocytic leukemia cell line (MOLT-4) were purchased from Cell Lines Service (Eppelheim, Germany). Leukemia cells were cultured in RPMI-1640 medium supplemented with 10% (v/v) FBS and 1% (v/v) penicillin–streptomycin (Gibco Life Technologies, Waltham, MA, USA)….

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Soniazid and ethionamide in Mycobacterium tuberculosis

Introduction Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the leading causes of death worldwide and caused 1.6 million deaths and 10.6 million new cases in 2021.1 Despite decades of efforts to adopt measures to control TB, achieving the goal of ending TB has been delayed due to a…

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Solved In RStudio:1. How can you tell if an object is a

In RStudio: 1. How can you tell if an object is a tibble? (Hint: try printing mtcars, which is a regular data frame). My verbal response to 1 is: 2. (1 point) What function would you use to read a file where fields were separated with “|”? My verbal response…

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Novartis Ireland hiring Principal RWE Research Analyst (Bioinformatics) in Dublin, County Dublin, Ireland

Job Description799 million. That’s how many lives our products touched in 2019. The Principal RWE Research Analyst, Bioinformatics is responsible for the scientific and methodological aspects of all Real World Evidence projects as well as providing guidance for other members of the team. In this role, we are looking for…

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