Tag: SPSS

Epidemiology, genetic diversity, and association of canine circovirus infection in dogs with respiratory disease

Animal and ethics A total of 190 dogs, comprising both healthy dogs (n = 76) and dogs with respiratory symptoms (n = 114), were included in this study. The research assessed nasal swab (NS) and oropharyngeal swab (OS) collected between January and November 2020. The samples from the healthy group were collected from clinically…

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How to Choose the Right Bioinformatics Position in 2022?

When you’re looking to land a good bioinformatics job, whether you’re a fresher, a career changer, or an experienced candidate, there’s usually a lot on your mind. And although the job search phase can look intimidating and exhausting, there has never been a better time to start a career in…

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Circular RNA circ-BNC2 (hsa_circ_0008732) inhibits the progression of ovarian cancer through microRNA-223-3p/ FBXW7 axis | Journal of Ovarian Research

Ethics statement and patient samples 40 pairs of OC tissues and adjacent tissue samples were collected from patients who were diagnosed with OC and received surgical resection in the Affiliated Hospital of Zunyi Medical University. None of the patients received any anti-cancer treatment before surgery, and all samples were immediately…

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Bronchoalveolar Lavage Fluid for Metagenomic Sequencing

Introduction Severe pneumonia is one of the most common causes of infectious diseases among patients in the intensive care unit (ICU), and this can lead to various complications and high mortality.1–3 Timely and accurate pathogen diagnoses are crucial for appropriate antimicrobial therapy and improved clinical outcomes. However, the low detection…

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Hydrogen Sulfide Ameliorated High Choline-Induced Cardiac Dysfunction by Inhibiting cGAS-STING-NLRP3 Inflammasome Pathway

Although it is an essential nutrient, high choline intake directly or indirectly via its metabolite is associated with increased risk of cardiovascular disease, the mechanism of which remains to be elucidated. The present study was performed to investigate whether hydrogen sulfide (H2S) was involved in high choline-induced cardiac dysfunction and…

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SMAD4 rs10502913 | COPD

1Department of Pulmonary and Critical Care Medicine, Sinopharm Tongmei General Hospital, Datong, People’s Republic of China; 2China-Japan Friendship Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 3Department of Emergency, Chinese PLA General Hospital -Fourth Medical Center, Beijing, People’s Republic of China; 4School…

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C698R mutation in Lrsam1 gene impairs nerve regeneration in a CMT2P mouse model

Animal generation The Lrsam1C698R knock-in mice were generated on a C57Bl/6J background using the CRISPR/Cas9 technique. Briefly, single-cell zygotes from C57BL/6J mice were microinjected with mRNA encoding Cas9 and a guide sequence (5′-ACAGCAGCAGACGTGGCCAC-3′ at 20 ng/µl) to target the exon 26 of Lrsam1. A single stranded DNA oligo carrying the C698R mutation…

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Frontiers | Serum and Serum Exosomal CircRNAs hsa_circ_0001492, hsa_circ_0001439, and hsa_circ_0000896 as Diagnostic Biomarkers for Lung Adenocarcinoma

Introduction Lung cancer is associated with high morbidity and mortality and continues to be a major public health problem worldwide (1). Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer. While the 5-year survival rates of patients with lung cancer are still <15%, rates are closer to…

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COVID-19 vaccines in liver transplant recipients

Introduction Three waves of world wild emerging severe infectious disease pandemics have been presented during this century because of the coronavirus. The severe acute respiratory syndrome (SARS) outbreak in southern China since 2002 has spread to 8096 cases from 29 countries, with a mortality of 9.6%.1 Middle East respiratory syndrome…

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boxplot – Ggplot geom_boxplot showing incorrect upper whisker and additional outlier

I am not sure why my boxplot created with ggplot geom_boxplot is showing an incorrect upper whisker and showing the data point (value = 7) as an outlier for “Male” grouping red boxplot. I have analyzed the same data sheet in SPSS and confirmed the Q1, Q3, and other values…

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1) use the data of

1) use the data of www.kaggle.com/code/ashydv/sales-prediction-simple-linear-regression/notebook (can use other data that contain 200 cases). 2) Using the random sample, build a regression model to predict sales (Y) and TV (X). 3) The analysis should include an assessment of the degree to which the key regression assumptions are satisfied. 4) If…

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Very important pharmacogene variants in the Blang population

Introduction The use of drugs should be different among diverse ethnic groups because of differences in ethnicity, age, sex, environmental factors and genetic factors. If these differences are ignored, then drug sensitivity, metabolic rate, and adverse reactions are affected, which influences the curative effect of drugs and aggravates the illness…

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Senior Data Analyst with RStudio / SAS / SPSS / Tableau – Long Term contract – Remote – A3279A – Technovision, Inc. –

WHAT ARE COOKIES? A cookie is a small file of letters and numbers that we store on your browser or the hard drive of your computer if you agree. Cookies contain information that is transferred to your computer’s hard drive. WHAT TYPES OF COOKIES DO WE USE? We use two…

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Problem-Solving Before Instruction (PS-I): A Protocol for Assessment and Intervention in Students with Different Abilities

This protocol guides researchers and educators through implementation of the Problem-Solving before Instruction approach (PS-I) in an undergraduate statistics class. It also describes an embedded experimental evaluation of this implementation, where the efficacy of PS-I is measured in terms of learning and motivation in students with different cognitive and affective…

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Therapeutic Potential of Exosomal circRNAin RA

Introduction Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial pannus formation resulting from angiogenesis accompanied by inflammation, which leads to cartilage and bone destruction.1 The inflammatory state in RA is maintained by the transport of inflammatory cells and oxygen to the synovium through enhanced angiogenesis. Therefore, angiogenesis…

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Correlation between MYO9B gene polymorphism and IBD

Introduction Inflammatory bowel disease (IBD) is chronic and recurrent intestinal inflammation of unknown etiology. Epidemiological data indicate that the incidence of IBD is high in Western regions, such as the Americas and Europe, and low in Asian regions. However, IBD has become increasingly common in Asia in recent years with…

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Pulmonary Infection Revealed by Metagenomic NGS

1Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology, Beijing, People’s Republic of China; 2Department of Clinical Laboratory, Beijing Capitalbio Medlab, Beijing, People’s Republic of China Background: Treatment of pulmonary infections in the intensive care unit (ICU) represents a great challenge, especially infections caused by…

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Chemotherapy only in older persons with PI-DLBCL

Introduction The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin’s lymphoma (NHL).1 Compared to the stomach, the intestine is the second most common site of primary GI lymphomas.2 Primary NHL of the GI tract accounts for 10–15% of all NHL cases and 1–4% of all GI tumours.3,4…

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Diagnostic markers of AIDS combined with TM infection

Introduction The prevalence of Human immunodeficiency virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) is still a public health problem that threatens the health of all human beings. According to the latest report of the World Health Organization, in the end of 2019, there were 38 million patients with human immunodeficiency virus/acquired immunodeficiency…

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Data Analytics Services Online | Fiverr

What is data analytics? Data analytics, put simply, is the process of collecting, cleaning, transforming, and organizing data to draw useful information from it. The information collected through data analytics is typically used to make well-informed and efficient business decisions. What are the benefits of data scraping? Data scraping is…

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Drug resistance mutations & genetic diversity of HIV1 in ART

Introduction At the end of 2018, 19.5 million people living with HIV were accessing ART globally.1 However, virological failure and development of drug resistance are becoming a bottleneck for the success of ART program. A global study involving 36 countries and 1926 patients with treatment failure from 1998–2015 reported that…

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Survival analysis of Hepatosplenic T cell lymphoma

Introduction Hepatosplenic T-cell lymphoma (HSTCL) is a rare and aggressive type of extranodal peripheral T-cell lymphoma. It was first described using the designation erythrophagocytic T γ lymphoma in 1981 by Kadin et al, and they reported two adults presenting with hepatosplenomegaly and minimal lymphadenopathy.1 Subsequently, the term hepatosplenic T-cell lymphoma…

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Transcriptome Sequencing Explores the Mechanism of Baicalin on Bone Ca

Introduction With the continuous improvement of cancer treatment technology, the 3-year and 5-year survival rates of cancer patients have been greatly improved. However, cancer still cause pain to the patients, which seriously affects their quality of life. This is because in many common cancers, tumors can easily metastase to the…

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Age- and gender-independent association of XRCC1 Arg399Gln

Introduction Chronic myeloid leukemia (CML) is a member of myeloproliferative neoplasms characterized by the acquired reciprocal chromosomal translocation, t(9;22) (q34; q11) which occurs as a result of translocation of ABL1 (Abelson murine leukemia) gene from chromosome 9 and its fusion with the BCR (breakpoint cluster region) gene on chromosome 22.1…

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R-Studio Assignment Help & Homework Help by R Studio Tutors

R Studio Assignment Help R Studio assignments can be intimidating at times. This is the reason why students avail R Studio assignment help free of bugs. If you find the task to be daunting, you too should consider availing R Studio assignments and solutions from Essayassignmenthelp.com.au. It is better to…

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Contingency table for “character” data – General

Hi, I would like to first, make a summary, contingency table for this data: mydata <- structure(list(Sex = c(“F”, “M”, “F”, “F”, “F”, “F”, “M”, “M”, “F”, “F”, “F”, “M”, “M”, “F”, “M”, “F”, “M”, “M”, “F”, “M”, “F”, “F”, “F”, “F”), Q1 = c(“A”, “A”, “A”, “A”, “A”, “A”,…

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Factors influencing multidrug-resistant tuberculosis | IDR

Introduction Pediatric tuberculosis (TB) is a significant global health threat and is one of the top ten causes of death in children.1 Globally, in 2019, an estimated 10.0 million people fell ill with TB, with children (aged under 15 years old) accounting for 12%, causing 1.4 million deaths.2 With the…

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PER1 as a Tumor Suppressor Attenuates Breast Cancer

Introduction Breast cancer is one of the most common malignancies in women, with a high mortality rate around the world.1,2 Although multidisciplinary therapeutic strategies, including surgical resection, chemoradiotherapy, endocrine and anti-HER2 therapy, have made substantial progress over the past decade, there are still a considerable proportion of breast cancer patients…

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Sequencing for pulmonary fungal infection diagnosis

Introduction In recent years, with the increase in high-risk groups requiring immunosuppressant use, the prevalence of pulmonary fungal disease has shown a significant upward trend. The main sources of fungal infections in human lungs are opportunistic fungi: Aspergillus, Cryptococcus, Pneumocystis jirovecii, and endemic fungi. Among them, Aspergillus and Cryptococcus are…

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Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the

Plain Language Summary Colorectal cancer progresses through a well‑defined series of transformations from normal colonic epithelial cells to precursor adenoma lesions that eventually evolve into increasingly more invasive and malignant stages. An improved understanding of the genetic and molecular drivers of colorectal cancer, especially the progression of adenoma to carcinoma,…

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Seroprevalence of Hepatitis B Virus and Associated Factors Among Femal

Introduction Hepatitis B virus (HBV) is a DNA virus belonging to the Hepadnaviridae family.1,2 Despite the availability of a safe and effective vaccine against hepatitis B infection for over two decades now, the overall burden of the disease remains enormous with over 2 billion people infected worldwide and approximately 1…

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H/ACA snoRNP gene family as diagnostic/prognostic biomarkers

Introduction Primary liver cancer, including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma, is the sixth most commonly diagnosed cancer and the fourth leading cause of cancer-related deaths worldwide.1 High metastasis and recurrence rates, as well as limited treatment options, lead to the poor prognosis of advanced HCC.2 Among patients diagnosed with…

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A TME-Related Signature as a Biomarker in Liver Cancer

Introduction As one of the most frequent causes of cancer deaths across the globe, liver cancer, characterized by high mortality, recurrence, metastasis and poor prognosis, is the only one of the top five deadliest cancers to have an annual percentage increase in occurrence.1 Surgery, local destructive therapies, and liver transplantation…

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ANGPTL8/betatrophin improves glucose tolerance | DMSO

Introduction Insulin resistance is a major risk factor for metabolic syndrome (MetS), including type 2 diabetes mellitus (T2DM).1 T2DM is characterized by insulin resistance in the liver.2 Insulin resistance is an abnormal physiological state that occurs when cells are unable to use insulin effectively, leading to T2DM, a major health…

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Bioinformatician | Chicago, IL | The University of Chicago

Bioinformatician | Chicago, IL | The University of Chicago Location: Start New Search: proteomicsremote work from homecomputational biologyvirologyresearch specialistresearch resultsresearch technicianpython rdieticiantitle researchgenomicspredictive analyticsreinsurancebiomedical researchbioinformaticshygienistcomputationalmolecular biologyimmunologydna The University of ChicagoChicago, IL Full-time Preferred Qualifications Education:Bioinformatics, Computational Biology, Computer Science, Mathematics, or a related fieldExperience: Experience in basic programming for bioinformatics…

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Quantitative PCR assay for detection of Helicobacter pylori

Introduction Helicobacter pylori is a common pathogen that infects nearly 50% of the global population.1 Infection with this pathogen causes chronic gastritis, which can cause chronic gastroduodenal diseases such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, and gastric mucosa-associated lymphoid tissue (MALT) B-cell lymphoma.2 Although H. pylori is the…

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Manager, Bioinformatics Group – Stanford University Careers

📁 📅    1 day ago Post Date 📅    91545 Requisition # Stanford University Department of Dermatology is seeking a Manager, Bioinformatics Group (Biostatistician 3) to conduct bioinformatic and statistical analysis and lead a team of bioinformaticians and lab members in order to facilitate biomedical…

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how to start a career in bioinformatics

After getting the required training needed in the field, there are several career opportunities that can be explored, considering that bioinformaticians have a special skill set, which makes them attractive for companies. As an interdisciplinary field of science, bioinformatics combines computer . They study biological and biochemical data at the…

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Multidrug-resistant Tuberculosis Strains in Southeast China

Introduction Multidrug-resistant TB (MDR-TB) infections, which result from transmission of Mycobacterium tuberculosis (MTB) strains with resistance to both rifampicin (RIF) and isoniazid (INH), continue to occur and are a major global public health issue. In 2019 an estimated 362,700 MDR-TB cases were detected worldwide, of which only 56.8% were properly…

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Genotype distribution and prevalence of human papillomavirus

Introduction Cervical cancer (CC) is the second most deadly disease among women in the world and is the leading cause of death from cancer.1 In 2018, there were 570,000 new diseases and 311,000 deaths worldwide.2 Viral infections contribute to 15–20% of all cancers, and several viruses play an important role…

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SNP of the SREK1 gene is associated with COPD in Kashi

Introduction Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disorder that progresses slowly and is characterized by an obstructive ventilatory pattern, which is rarely reversible. The main risk factors are active smoking, genetic factors, and air pollution. In particular, COPD has been a major public health problem and will…

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High tumor mutation burden and DNA repair gene mutations

Introduction Anaplastic lymphoma kinase (ALK)‑fusion genes represent a small but important part of oncogenic driver mutations in NSCLC, accounting for approximately 3%‑7% of all cases worldwide.1,2 Small molecule tyrosine kinase inhibitors (TKIs) are the standard therapy for ALK-rearranged NSCLC. Crizotinib, a first-generation TKI, is the most widely used targeted drug…

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P. aeruginosa isolated from patients with aural infections

Introduction Aural infections are one of the most common diseases of the head and neck and are predominantly caused by bacterial infections of the ear canal. Several studies from different countries have reported that Pseudomonas aeruginosa is the most common pathogen isolated from ear canal secretions, followed by Staphylococcus aureus.1…

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Modification of endoglin-targeting nanoliposomes | IJN

Introduction Today, malignant tumors (cancer) still severely imperil human health and cause millions of global mortality rates.1,2 Deep-seated solid tumors are challenging to cure by most therapeutic tools, mainly blamed on the complex tumor microenvironment (TME).3,4 Adoptive cell therapy (ACT), as one of the effective immunotherapeutic means for cancer treatment,…

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Prevalence and Molecular Characteristics Based on Whole Genome Sequenc

Introduction Tuberculosis, caused by Mycobacterium tuberculosis, remains one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent (ranking above HIV/AIDS).1 In 2020, World Health Organization (WHO) reported that 7.1 million people with tuberculosis were newly diagnosed and notified in 2019,…

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Survival Analysis Cut-off

Survival Analysis Cut-off 0 Hello guys, I am doing a survival analysis using TCGA-BRCA project data. I am trying different cut-offs to separate my samples into high and low risk groups, but since it is my first time I would like to ask a question just to be fully sure…

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