Tag: SPSS

Administration Guide – R Package Dependencies

The following is a list of all of the R packages RStudio depends on in some way. None of these packages are necessary for the basic operation of RStudio; they all enable additional IDE functionality as noted in in Features. This information is also available in the IDE itself using…

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Comparison and fusion prediction model for lung adenocarcinoma with micropapillary and solid pattern using clinicoradiographic, radiomics and deep learning features

Patients This respective multicohort study was approved by the Institutional Review Board of The First Affiliated Hospital of Nanjing Medical University (Permit Number: 2021-SRFA-238) and the Institutional Review Board of the Affiliated Huaian NO.1 People’s Hospital of Nanjing Medical University (Permit Number: 2022-0451-01), respectively. And the requirement of written informed consent…

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Association between ANGPTL3, 4, 8 and CVRF in HTN

Fangfang Xu,1,* Lijun Shen,2,* Yongguang Yang,2 Limin Kong,3 Wufan Zu,4 Dandan Tian,5 Xuanchao Cao,1 Gairong Huang1 1Key Laboratory of Geriatrics, Institute of Geriatrics, Department of Geriatric Medicine, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China; 2Department of Clinical Medical Research Center, Henan Provincial People’s…

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how to export data from rstudio to excel

You need to write the path of the file in the function drop_delete(), We can summarize all the functions in the table below, Copyright – Guru99 2023 Privacy Policy|Affiliate Disclaimer|ToS, How to Export a DataFrame to a CSV File in R, How to Export a Data from R to Excel…

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MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways

Cell lines Human melanoma cell lines (A375 and A875) were kindly donated by the Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology. Cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM) supplemented with 10% FBS, 100 μg/ml penicillin and 100 μg/ml streptomycin at 37 °C in a…

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Human bone marrow-derived mesenchymal stem overexpressing microRNA-124-3p inhibit DLBCL progression by downregulating the NFATc1/cMYC pathway | Stem Cell Research & Therapy

Microarray-based expression analysis and GEO database analysis The DLBCL-related miRNA expression profiles of GSE29493 and GSE40239 were retrieved from the Gene Expression Omnibus (GEO) database (www.ncbi.nlm.nih.gov/geo/). MiR-124’s pan cancer analysis is conducted through online websites (www.picb.ac.cn/dbDEMC/). Bioinformatics predicted NFATc1 as the target of miR-124-3p The miRbase (www.mirbase.org/), miRDB (mirdb.org), and…

Continue Reading Human bone marrow-derived mesenchymal stem overexpressing microRNA-124-3p inhibit DLBCL progression by downregulating the NFATc1/cMYC pathway | Stem Cell Research & Therapy

Value of mNGS for rapid diagnosis of spinal tuberculosis

Introduction Mycobacterium tuberculosis (MTB) infection in humans leading to tuberculosis (TB), which is an ancient infectious disease that threatens public health.1 TB can be categorized as extrapulmonary TB (EPTB) or pulmonary TB according to the status of MTB infection in the lungs.2 Notably, EPTB is the collective term for all…

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Alterations of mtDNA copy number and 4977 bp deletion induced by ionizing radiation in human peripheral blood

Alterations of mtDNA copy number and 4977 bp deletion induced by ionizing radiation in human peripheral blood 2 first-author 1 1 1 3 1 1 3 corresp Corresponding author. E-mail address: lym636160@sina.com Corresponding author. E-mail address: lym636160@sina.com lym636160@sina.com Henan Institute of Occupational Medicine, Zhengzhou 450052, China Henan Institute of Occupational…

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Intro to R and RStudio (beginner)

Is R the right tool for your data analysis needs? 1. A software for statistical computing and graphics R vs other statistical software such as SPSS, SAS, STATA, Mplus, HLM etc. : Pros Accessibility: R is free and open-source, while other statistical software like SPSS is proprietary software that requires…

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Scholarships and Career Opportunities: Postdoctoral in bioinformatics

Description of the workplaceThe Cardiovascular research – Translational studies is studying cardiovascular disease with a focus on biological differences that underlie acute complications such as heart attacks and strokes. The research is translational and includes studies of human tissue and several in-vitro models. The group has for many years been…

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Pathogen Diagnosis Value of Nanopore Sequencing

Introduction Severe hospital-acquired pneumonia (SHAP) is the most common acquired infection in the intensive care unit (ICU) and one of the main causes of increased mortality in ICU patients.1,2 Potential multidrug-resistant pathogens are very common in ICU-acquired pneumonia, including Pseudomonas aeruginosa, Acinetobacter spp., methicillin-resistant Staphylococcus aureus (MRSA), and ultrabroad spectrum…

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BRAFV600E, BRAFK601E, NRAS, HRAS, and KRAS mutational status

Agnes Stephanie Harahap,1– 3 Imam Subekti,4 Sonar Soni Panigoro,5 Asmarinah,6 Lisnawati,1 Retno Asti Werdhani,7 Hasrayati Agustina,8 Dina Khoirunnisa,1 Mutiah Mutmainnah,1 Salinah,1 Alvita Dewi Siswoyo,9 Maria Francisca Ham1,2 1Department of Anatomical Pathology, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; 2Human Cancer Research Center-Indonesian Medical Education and Research Institute,…

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Postdoctoral in bioinformatics – Academic Positions

Lund University, Faculty of Medicine, Department of Clinical Sciences, Malmö Description of the workplaceThe Cardiovascular research – Translational studies is studying cardiovascular disease with a focus on biological differences that underlie acute complications such as heart attacks and strokes. The research is translational and includes studies of human tissue and…

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Pinostrobin, a fingerroot compound, regulates miR-181b-5p and induces acute leukemic cell apoptosis

Leukemia cell culture The human acute promyelocytic leukemia cell line (NB4) and the human acute lymphocytic leukemia cell line (MOLT-4) were purchased from Cell Lines Service (Eppelheim, Germany). Leukemia cells were cultured in RPMI-1640 medium supplemented with 10% (v/v) FBS and 1% (v/v) penicillin–streptomycin (Gibco Life Technologies, Waltham, MA, USA)….

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Soniazid and ethionamide in Mycobacterium tuberculosis

Introduction Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the leading causes of death worldwide and caused 1.6 million deaths and 10.6 million new cases in 2021.1 Despite decades of efforts to adopt measures to control TB, achieving the goal of ending TB has been delayed due to a…

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Solved In RStudio:1. How can you tell if an object is a

In RStudio: 1. How can you tell if an object is a tibble? (Hint: try printing mtcars, which is a regular data frame). My verbal response to 1 is: 2. (1 point) What function would you use to read a file where fields were separated with “|”? My verbal response…

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Novartis Ireland hiring Principal RWE Research Analyst (Bioinformatics) in Dublin, County Dublin, Ireland

Job Description799 million. That’s how many lives our products touched in 2019. The Principal RWE Research Analyst, Bioinformatics is responsible for the scientific and methodological aspects of all Real World Evidence projects as well as providing guidance for other members of the team. In this role, we are looking for…

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The role of FMT in T2D and its underlying mechanisms.

Background The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide, with an estimated global prevalence of approximately 552 million by 2030.1 Long-term hyperglycemia in T2D patients can lead to vascular endothelial damage, which includes microvascular disease such as diabetic retinopathy and nephropathy, neuropathy, and macrovascular disease including peripheral…

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Mosquito densovirus significantly reduces the vector susceptibility to dengue virus serotype 2 in Aedes albopictus mosquitoes (Diptera: Culicidae) | Infectious Diseases of Poverty

Identification of MDV presence using open access sequencing data Metagenomic next-generation sequencing (NGS) data for field mosquitoes in China were searched from the NCBI SRA database (www.ncbi.nlm.nih.gov/sra) and CNGB Sequence Archive database (db.cngb.org/cnsa/) using the keywords “mosquito OR Anopheles OR Aedes OR Culex”. Followed by removing the datasets with less…

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Data Analyst at Phase3 Telecom Limited

Jobs Phase3 Telecom is a leading independent fibre optic infrastructure with Points-of-Presence (POPs), colocation, and NOCs in Nigeria. Issued a National Long Distance Operator (NLDO) licence in 2003 by the Nigerian Communications Commission (NCC), and with a vibrant as well as a dedicated team of experienced professionals, we are the…

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Research Assistant, Theranostics Centre for Excellence – Diagnostic Radiology job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The National University of Singapore invites applications for multiple Research Assistant positions for the Theranostics Centre for Excellence (TCE) in the Department of Diagnostic Radiology, Yong Loo Lin School of Medicine.  The TCE is committed to developing various forms of cancer theranostics (therapeutics and diagnostics) that are clinically translatable. The center…

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Mechanism of radix astragali therapy against hyperuricemia

Introduction Hyperuricemia is a disease caused by irregular purine metabolism, which is always accompanied by excessive production or abnormal excretion of uric acid (UA).1 Most notably, the overall incidence of hyperuricemia in China has been increasing over the past decade with the westernization of eating habits.2,3 However, there are blind…

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Illumina MiSeq sequencing investigation on the contrasting rhizosphere soil bacterial community structures in tea orchard soil under different content of aluminium

Introduction Tea trees (Camellia sinensis (L.) O. Kuntze) are among the most important economic trees in the world, as an important economic crop, which is widely planted in acidic soil in the tropical and sub-tropical zones of China (Liu et al. Citation2019). Meanwhile, tea is an aluminium (Al) accumulating plant that…

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MTX Therapy Outcomes in Early Rheumatoid Arthritis

Introduction Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, mainly characterised by symmetrical pain and swelling of small joints in the hands and the feet.1 When chronic inflammation is not properly controlled over a long period of time, it can eventually lead to irreversible damage to the joint structures….

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The cost-effectiveness of whole genome sequencing in neurodevelopmental disorders

Study design This study was designed as a retrospective observational study that compared historical data on healthcare costs, diagnostic yield and type of genetic tests between two cohorts of patients referred to the department of Clinical Genetics at the Karolinska University Hospital. One cohort (cohort CMA) represented standard care, with…

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Research Fellow (Paediatrics – Allergy & Immunology) job with NATIONAL UNIVERSITY OF SINGAPORE

Job Description The Division of Allergy & Immunology at the Department of Paediatrics, Yong Loo Lin School of Medicine, NUS is looking for highly motivated and enthusiastic candidates with a keen interest in clinical translational research in allergic disease epidemiology and pathophysiology to join our team as a Research Fellow….

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C R Package Dependencies | RStudio Server Professional Edition 1.3.937-3

base64enc 0.1-3 R Markdown crayon 1.3.4 Plumber R APIs, Shiny curl 4.2 Publishing DBI 0.8 Database Interface, RSQLite devtools 1.11.1 R Unit Testing digest 0.6 R Markdown, Shiny evaluate 0.13 R Markdown glue 1.3.0 R Markdown haven 0.2.0 SPSS/SAS/Stata Import highr 0.3 R Markdown htmltools 0.3.6 R2D3, R Markdown, Shiny,…

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r – Repel / shadow text on ggplot2 likert() bar plot

I’m experimenting with labels on likert() plot bars. Having fiddled with possible tools like ggrepel() and with_shadow() from ggfx(), I can’t seem to identify the specific name of the element that I want to act on. I’m aware that geom_text_repel() will require me to specify aes() elements, but as these…

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Diagnostic Significance of Targeted Next-Generation Sequencing in Cent

Introduction Neurosurgical infections affecting the central nervous system (CNS) encompass post-operative epidural abscesses, subdural pus, meningitis, brain abscesses, intracranial infections resulting from craniocerebral trauma, extraventricular and lumbar pool drainage, shunts, and meningitis associated with implants.1,2 In children, CNS infections can have a profound impact on neurological development. Acute symptoms may…

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Garden cress seeds ameliorated Aluminum-induced Alzheimers

Introduction Exposure of humans to aluminum has significantly increased worldwide. Potential sources of aluminum exposure include drinking water, food, medicines, vaccines, and aluminum cookware utensils. Aluminum bioaccumulation in the brain has been associated with neuroinflammatory and neurodegenerative changes that might predispose to Alzheimer’s disease (AD).1 Subchronic administration of Al3+ to rats…

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Statistics, Economics and statistical data analysis projects by using Rstudio, SPSS, Minitab, Python and Excel

About ADNAN Greetings! Are you struggling with statistics, Economics and probability assignments, projects and courses? I am a statistician with 5 years of experience have done my Ph.D. degree in Statistics and looking forward to helping you will types of Statistical Data Analysis in SPSS, Excel, STATA, Minitab, and R…

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Research Associate in Genomics job with KINGS COLLEGE LONDON

Job description The postholder will have a leading role in an exciting new Motor Neurone Disease Association funded project. The project is a collaboration between researchers working in motor neuron disease (MND), and computer scientists working with biological information.        You will develop, maintain and run bioinformatics pipelines…

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The apoptotic effects of soybean agglutinin were induced through three different signal pathways by down-regulating cytoskeleton proteins in IPEC-J2 cells

SBA-induced cell cycle arrest at G0/G1 phase and increased the apoptotic rates The Nuclear staining with PI/RNase compound is an indicator for the cell cycle phase. The abilities of SBA to interfere with cell cycle progression and to increase cell apoptosis rates were determined by FCM. After IPEC-J2, cells were…

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Foods | Free Full-Text | A Rapid RPA-CRISPR/Cas12a Detection Method for Adulteration of Goat Milk Powder

1. Introduction Since 1960s, goat milk has attracted people’s attention as high-value milk [1]. Its composition is similar to human milk, and it is rich in nutrients with low allergenicity [2]. In addition, goat milk contains active factors such as superoxide dismutase and DHA [3], which are beneficial to human…

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A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis

Introduction Osteoarthritis (OA) is a chronic musculoskeletal disease with a polygenic and heterogeneous nature that involves movable joints. The set of features that take place during the development of the disease lead to consider OA as a severe disease of the whole joint as an organ.1–3 The aetiology of knee…

Continue Reading A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis

Clinical Efficacy and Diagnostic Value of Metagenomic Next-Generation

Introduction Infections are the major cause of human deaths worldwide and present a rising threat to public security.1 Antimicrobial resistance is a major concern that is threatening our ability to treat bacterial infections.2 Delayed administration of antibiotics significantly increases the in-hospital mortality rate.3 The tragic outcome of infection highlights the…

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Research Assistant, Centre for Applied Research job with SINGAPORE UNIVERSITY OF SOCIAL SCIENCES

Short Description Research Assistant (1 year contract) The successful candidate will provide research and administrative support for an ongoing research project by a SUSS faculty member examines the use of assistive technology for the elderly in Singapore.  Job Description Provide research support Conduct literature review Recruit participants for interviews …

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magnusmanske / wikidata-game / issues / #343

LINK >>>>> fancli.com/2t4M2m You need Adobe® Acrobat® Reader to view Acrobat® Portable document files (.PDF). You can download it for free from Acrobat® Software®. You may require an Activation Code for Adobe® Acrobat® Reader to complete activation. Please contact the IT Service Desk to obtain this code. You can also…

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rpubs – Avnew

Easy web publishing from R. Write R Markdown documents in RStudio. Share them here on RPubs. (It’s free, and couldn’t be simpler!)RStudio lets you harness the power of R Markdown to create documents that weave together your writing and the output of your R code. And now, with RPubs, you …RPubs…

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Osteoporotic Fracture in Postmenopausal Chinese Females

Introduction Osteoporosis is a frequently diagnosed disease of the bone featured by reduced bone tissue quality as well as a reduced mass of bone tissues. It was determined that > 20 million people suffer from various degrees of osteoporosis at any moment.1,2 Although various therapeutic approaches and agents, such as…

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Photo-functionalized TiO2 film for facile immobilization of EpCAM antibodies and efficient enrichment of circulating tumor cells

1 Introduction Cancer is a significant public health threat, inducing more than 10 million deaths in 2020 worldwide (Sung et al., 2021). Circulating tumor cells (CTCs) are cancer cells that are shed from the primary lesion of a solid tumor, enter the circulation and/or lymphatic system, and translocate to distant…

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Posit’s Value: Customer Stories Behind The Most Loved Data Science Products

It’s challenging to think of a niche that became more saturated than data science in the last couple of years. Thousands of startups are coming up with hit-and-miss products and services daily, so staying relevant is easier said than done. Today we’ll see how one major player – Posit (formerly…

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Plastid DNA sequences and oospore characters of some European taxa of Tolypella section Tolypella (Characeae) identify five clusters, including one new cryptic Tolypella taxon from Sardinia, but they do not coincide with current morphological descriptions

1. Introduction Charophytes, extant and fossil members of the order Charales plus the members of the extinct orders Sycidiales and Moellerinales (Schneider et al., 2015) are algae with a complex morphology, which are closely related to modern land plants (Nishiyama et al., 2018). Taxa delineation of charophytes is commonly based on morphological…

Continue Reading Plastid DNA sequences and oospore characters of some European taxa of Tolypella section Tolypella (Characeae) identify five clusters, including one new cryptic Tolypella taxon from Sardinia, but they do not coincide with current morphological descriptions

Molecular Epidemiology of Klebsiella pneumoniae

Introduction Klebsiella pneumoniae (KPN) is a common gram-negative bacterium that causes clinical infection, and studies have shown that it has the second-highest detection rate among all bacterial infections.1,2 Compared with common KPN (ie classic KPN [cKP]), hypervirulent KPN (HvKP) has the following characteristics: (1) Usually, HvKP colonies display a high-mucus…

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CircFNDC3B regulates osteoarthritis and oxidative stress by targeting miR-525-5p/HO-1 axis

Human cartilage and chondrocytes Collections of human cartilage samples were according to protocols approved by the Ethics Committee of Sir Run Run Shaw Hospital (Hangzhou, China), and the methods were carried out in accordance with the approved guidelines. All subjects signed a written informed consent. Human cartilage samples were obtained…

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Metagenomic next-generation sequencing of plasma

Introduction Metagenomic next-generation sequencing (mNGS), a new pathogen detection technology, does not rely on sequence amplification of specific gene primers. It is increasingly used in clinical pathogen detection due to its short sequencing time1 and high sensitivity, and the approximate detection sensitivity range is 68%-88%.2,3 We found that the overall…

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TCF7L2 acts as a molecular switch in midbrain to control mammal vocalization through its DNA binding domain but not transcription activation domain

An ENU-induced mutagenesis screening for genes involved in mouse vocalization To identify novel genes involved in mouse vocalization, we set up an ENU-induced mutagenesis screening (Fig. 1a). To this end, we crossed ENU-treated G0 males with untreated C57BL/6 J females, and through the use of an USV detector, identified G1 pups with…

Continue Reading TCF7L2 acts as a molecular switch in midbrain to control mammal vocalization through its DNA binding domain but not transcription activation domain

ST7 becomes one of the most common S. aureus clones

Introduction Staphylococcus aureus (S. aureus), a major human opportunistic pathogen, can cause a variety of infectious diseases including skin and soft-tissue infections, bacteremia, ventilator-associated pneumonia and toxic shock syndrome.1,2 A rapid and proper administration of antibiotics is the most important means to inhibit S. aureus’ growth and prevent disease progression….

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Medial retropharyngeal nodal region sparing radiotherapy versus standard radiotherapy in patients with nasopharyngeal carcinoma: open label, non-inferiority, multicentre, randomised, phase 3 trial

Abstract Objectives To address whether sparing the medial retropharyngeal lymph node (MRLN) region from elective irradiation volume provides non-inferior local relapse-free survival versus standard radiotherapy in patients with nasopharyngeal carcinoma. Design Open-label, non-inferiority, multicentre, randomised, phase 3 trial. Setting Three Chinese hospitals between 20 November 2017 and 3 December 2018….

Continue Reading Medial retropharyngeal nodal region sparing radiotherapy versus standard radiotherapy in patients with nasopharyngeal carcinoma: open label, non-inferiority, multicentre, randomised, phase 3 trial

Molecular characterization and antimicrobial susceptibility profiles of Thai Mycoplasma synoviae isolates

Isolation of M. synoviae field isolates M. synoviae field isolates were obtained from approximately ninety flocks of registered commercial chicken farms, including breeder flocks, broiler flocks, and layer flocks in Thailand in 2020. Chickens were individually swabbed at the articular joint or the respiratory tract; choanal cleft, tra,chea and airsac;…

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Development and clinical evaluation of a CRISPR/Cas13a-based diagnostic test to detect Mycobacterium tuberculosis in clinical specimens

Introduction Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB) complex, remains one of the leading infectious causes of death worldwide, with an estimated 1.6 million TB deaths in 2021 (World Health Organization, 2022). Rapid and accurate TB diagnosis is critical to ensure timely initiation of anti-TB therapy (Walzl et al., 2018)….

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Plasmatic circRNA Predicting the Occurrence of Human Glioblastoma

Introduction Gliomas are defined as human malignant tumors derived from glial cells. Gliomas account for almost 80% of all malignant brain tumors.1 To date, gliomas have beendivided into four subgroups from I to IV according to the pathologic grading system.2 The prognosis was associated with the subgroup. For the gliomas, lower…

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Solved Link to download the data as an Excel file since I

Link to download the data as an Excel file since I cannot attach the Excel file myself – or please let me know if there is an easier way to provide this Excel file –www.kaggle.com/datasets/aungpyaeap/supermarket-sales?resource=download Use SPSS to conduct a descriptive analysis using the columns: Customer Type and Total. In…

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Molecular epidemiology of CRKP | IDR

Introduction Klebsiella pneumoniae (Kp; K. pneumoniae) is an important hospital and community-acquired pathogen that primarily causes pneumonia, urinary tract infections, bloodstream-associated infections, meningitis, and pyogenic liver abscess.1–3 Carbapenem antibiotics represent the most important treatment for Enterobacteriaceae; however, with the widespread use of such antibiotics, carbapenem-resistant K. pneumoniae (CRKP) is increasingly…

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Multi-pathogenic pneumonia in HIV-infected patients

Introduction Pulmonary infection is the most common cause of morbidity and mortality in immunocompromised patients.1 The pathogens spectrum of pneumonia that can affect patients with human immunodeficiency virus (HIV) is wide, such as bacterial, fungal, viral, parasitic organisms, and so on.2–4 Compared to patients with monomicrobial pulmonary infection, the clinical…

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Bioinformatician III – UF Health Cancer Center job with University of Florida

Bioinformatician III – UF Health Cancer Center Job No: 523970Work Type: Location: Main Campus (Gainesville, FL)Categories: RealCatDepartment: 29300700 – MD-SHARED RESOURCES Job Description Classification Title: Bioinformatics Analyst III Job Description: As part of our Division of Quantitative Sciences and the Biostatistics & Quantitative Sciences Shared Resource, you will be responsible…

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Journal Of Pakistan Medical Association

Manzar Abbas  ( 5th Year MBBS Student. )Hareem Rauf  ( 4th Year MBBS Student. )Javeria Bilal Qamar  ( 3rd Year MBBS Student. )Syeda Ramlah Tul Sania  ( 5th Year MBBS Student. )Russell Seth Martins  ( Department of Pediatrics and Child Health. )Zahra Hasan  ( Aga Khan University, Karachi, Pakistan, ) …

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Effects of different applied voltages of irreversible electroporation on prostate cancer in a mouse model

Cell culture The human prostate cancer cell line (DU145) was purchased from Korean Cell Line Bank (Pohang, Korea). The cells were cultured in Roswell Park Memorial Institute 1640 medium with L-glutamine (300 mg/L), 25 mM HEPES, and 25 mM NaHCO3 and supplemented with 10% fetal bovine serum (FBS; Sigma-Aldrich, St. Louis, MI, USA),…

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Epidemiology, genetic diversity, and association of canine circovirus infection in dogs with respiratory disease

Animal and ethics A total of 190 dogs, comprising both healthy dogs (n = 76) and dogs with respiratory symptoms (n = 114), were included in this study. The research assessed nasal swab (NS) and oropharyngeal swab (OS) collected between January and November 2020. The samples from the healthy group were collected from clinically…

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How to Choose the Right Bioinformatics Position in 2022?

When you’re looking to land a good bioinformatics job, whether you’re a fresher, a career changer, or an experienced candidate, there’s usually a lot on your mind. And although the job search phase can look intimidating and exhausting, there has never been a better time to start a career in…

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Circular RNA circ-BNC2 (hsa_circ_0008732) inhibits the progression of ovarian cancer through microRNA-223-3p/ FBXW7 axis | Journal of Ovarian Research

Ethics statement and patient samples 40 pairs of OC tissues and adjacent tissue samples were collected from patients who were diagnosed with OC and received surgical resection in the Affiliated Hospital of Zunyi Medical University. None of the patients received any anti-cancer treatment before surgery, and all samples were immediately…

Continue Reading Circular RNA circ-BNC2 (hsa_circ_0008732) inhibits the progression of ovarian cancer through microRNA-223-3p/ FBXW7 axis | Journal of Ovarian Research

Bronchoalveolar Lavage Fluid for Metagenomic Sequencing

Introduction Severe pneumonia is one of the most common causes of infectious diseases among patients in the intensive care unit (ICU), and this can lead to various complications and high mortality.1–3 Timely and accurate pathogen diagnoses are crucial for appropriate antimicrobial therapy and improved clinical outcomes. However, the low detection…

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Hydrogen Sulfide Ameliorated High Choline-Induced Cardiac Dysfunction by Inhibiting cGAS-STING-NLRP3 Inflammasome Pathway

Although it is an essential nutrient, high choline intake directly or indirectly via its metabolite is associated with increased risk of cardiovascular disease, the mechanism of which remains to be elucidated. The present study was performed to investigate whether hydrogen sulfide (H2S) was involved in high choline-induced cardiac dysfunction and…

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SMAD4 rs10502913 | COPD

1Department of Pulmonary and Critical Care Medicine, Sinopharm Tongmei General Hospital, Datong, People’s Republic of China; 2China-Japan Friendship Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 3Department of Emergency, Chinese PLA General Hospital -Fourth Medical Center, Beijing, People’s Republic of China; 4School…

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C698R mutation in Lrsam1 gene impairs nerve regeneration in a CMT2P mouse model

Animal generation The Lrsam1C698R knock-in mice were generated on a C57Bl/6J background using the CRISPR/Cas9 technique. Briefly, single-cell zygotes from C57BL/6J mice were microinjected with mRNA encoding Cas9 and a guide sequence (5′-ACAGCAGCAGACGTGGCCAC-3′ at 20 ng/µl) to target the exon 26 of Lrsam1. A single stranded DNA oligo carrying the C698R mutation…

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Frontiers | Serum and Serum Exosomal CircRNAs hsa_circ_0001492, hsa_circ_0001439, and hsa_circ_0000896 as Diagnostic Biomarkers for Lung Adenocarcinoma

Introduction Lung cancer is associated with high morbidity and mortality and continues to be a major public health problem worldwide (1). Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer. While the 5-year survival rates of patients with lung cancer are still <15%, rates are closer to…

Continue Reading Frontiers | Serum and Serum Exosomal CircRNAs hsa_circ_0001492, hsa_circ_0001439, and hsa_circ_0000896 as Diagnostic Biomarkers for Lung Adenocarcinoma

COVID-19 vaccines in liver transplant recipients

Introduction Three waves of world wild emerging severe infectious disease pandemics have been presented during this century because of the coronavirus. The severe acute respiratory syndrome (SARS) outbreak in southern China since 2002 has spread to 8096 cases from 29 countries, with a mortality of 9.6%.1 Middle East respiratory syndrome…

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boxplot – Ggplot geom_boxplot showing incorrect upper whisker and additional outlier

I am not sure why my boxplot created with ggplot geom_boxplot is showing an incorrect upper whisker and showing the data point (value = 7) as an outlier for “Male” grouping red boxplot. I have analyzed the same data sheet in SPSS and confirmed the Q1, Q3, and other values…

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1) use the data of

1) use the data of www.kaggle.com/code/ashydv/sales-prediction-simple-linear-regression/notebook (can use other data that contain 200 cases). 2) Using the random sample, build a regression model to predict sales (Y) and TV (X). 3) The analysis should include an assessment of the degree to which the key regression assumptions are satisfied. 4) If…

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Very important pharmacogene variants in the Blang population

Introduction The use of drugs should be different among diverse ethnic groups because of differences in ethnicity, age, sex, environmental factors and genetic factors. If these differences are ignored, then drug sensitivity, metabolic rate, and adverse reactions are affected, which influences the curative effect of drugs and aggravates the illness…

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Senior Data Analyst with RStudio / SAS / SPSS / Tableau – Long Term contract – Remote – A3279A – Technovision, Inc. –

WHAT ARE COOKIES? A cookie is a small file of letters and numbers that we store on your browser or the hard drive of your computer if you agree. Cookies contain information that is transferred to your computer’s hard drive. WHAT TYPES OF COOKIES DO WE USE? We use two…

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Problem-Solving Before Instruction (PS-I): A Protocol for Assessment and Intervention in Students with Different Abilities

This protocol guides researchers and educators through implementation of the Problem-Solving before Instruction approach (PS-I) in an undergraduate statistics class. It also describes an embedded experimental evaluation of this implementation, where the efficacy of PS-I is measured in terms of learning and motivation in students with different cognitive and affective…

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Therapeutic Potential of Exosomal circRNAin RA

Introduction Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial pannus formation resulting from angiogenesis accompanied by inflammation, which leads to cartilage and bone destruction.1 The inflammatory state in RA is maintained by the transport of inflammatory cells and oxygen to the synovium through enhanced angiogenesis. Therefore, angiogenesis…

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Correlation between MYO9B gene polymorphism and IBD

Introduction Inflammatory bowel disease (IBD) is chronic and recurrent intestinal inflammation of unknown etiology. Epidemiological data indicate that the incidence of IBD is high in Western regions, such as the Americas and Europe, and low in Asian regions. However, IBD has become increasingly common in Asia in recent years with…

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Pulmonary Infection Revealed by Metagenomic NGS

1Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology, Beijing, People’s Republic of China; 2Department of Clinical Laboratory, Beijing Capitalbio Medlab, Beijing, People’s Republic of China Background: Treatment of pulmonary infections in the intensive care unit (ICU) represents a great challenge, especially infections caused by…

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Chemotherapy only in older persons with PI-DLBCL

Introduction The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin’s lymphoma (NHL).1 Compared to the stomach, the intestine is the second most common site of primary GI lymphomas.2 Primary NHL of the GI tract accounts for 10–15% of all NHL cases and 1–4% of all GI tumours.3,4…

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Diagnostic markers of AIDS combined with TM infection

Introduction The prevalence of Human immunodeficiency virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) is still a public health problem that threatens the health of all human beings. According to the latest report of the World Health Organization, in the end of 2019, there were 38 million patients with human immunodeficiency virus/acquired immunodeficiency…

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Data Analytics Services Online | Fiverr

What is data analytics? Data analytics, put simply, is the process of collecting, cleaning, transforming, and organizing data to draw useful information from it. The information collected through data analytics is typically used to make well-informed and efficient business decisions. What are the benefits of data scraping? Data scraping is…

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Drug resistance mutations & genetic diversity of HIV1 in ART

Introduction At the end of 2018, 19.5 million people living with HIV were accessing ART globally.1 However, virological failure and development of drug resistance are becoming a bottleneck for the success of ART program. A global study involving 36 countries and 1926 patients with treatment failure from 1998–2015 reported that…

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Survival analysis of Hepatosplenic T cell lymphoma

Introduction Hepatosplenic T-cell lymphoma (HSTCL) is a rare and aggressive type of extranodal peripheral T-cell lymphoma. It was first described using the designation erythrophagocytic T γ lymphoma in 1981 by Kadin et al, and they reported two adults presenting with hepatosplenomegaly and minimal lymphadenopathy.1 Subsequently, the term hepatosplenic T-cell lymphoma…

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Transcriptome Sequencing Explores the Mechanism of Baicalin on Bone Ca

Introduction With the continuous improvement of cancer treatment technology, the 3-year and 5-year survival rates of cancer patients have been greatly improved. However, cancer still cause pain to the patients, which seriously affects their quality of life. This is because in many common cancers, tumors can easily metastase to the…

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Age- and gender-independent association of XRCC1 Arg399Gln

Introduction Chronic myeloid leukemia (CML) is a member of myeloproliferative neoplasms characterized by the acquired reciprocal chromosomal translocation, t(9;22) (q34; q11) which occurs as a result of translocation of ABL1 (Abelson murine leukemia) gene from chromosome 9 and its fusion with the BCR (breakpoint cluster region) gene on chromosome 22.1…

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R-Studio Assignment Help & Homework Help by R Studio Tutors

R Studio Assignment Help R Studio assignments can be intimidating at times. This is the reason why students avail R Studio assignment help free of bugs. If you find the task to be daunting, you too should consider availing R Studio assignments and solutions from Essayassignmenthelp.com.au. It is better to…

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Contingency table for “character” data – General

Hi, I would like to first, make a summary, contingency table for this data: mydata <- structure(list(Sex = c(“F”, “M”, “F”, “F”, “F”, “F”, “M”, “M”, “F”, “F”, “F”, “M”, “M”, “F”, “M”, “F”, “M”, “M”, “F”, “M”, “F”, “F”, “F”, “F”), Q1 = c(“A”, “A”, “A”, “A”, “A”, “A”,…

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Factors influencing multidrug-resistant tuberculosis | IDR

Introduction Pediatric tuberculosis (TB) is a significant global health threat and is one of the top ten causes of death in children.1 Globally, in 2019, an estimated 10.0 million people fell ill with TB, with children (aged under 15 years old) accounting for 12%, causing 1.4 million deaths.2 With the…

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PER1 as a Tumor Suppressor Attenuates Breast Cancer

Introduction Breast cancer is one of the most common malignancies in women, with a high mortality rate around the world.1,2 Although multidisciplinary therapeutic strategies, including surgical resection, chemoradiotherapy, endocrine and anti-HER2 therapy, have made substantial progress over the past decade, there are still a considerable proportion of breast cancer patients…

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Sequencing for pulmonary fungal infection diagnosis

Introduction In recent years, with the increase in high-risk groups requiring immunosuppressant use, the prevalence of pulmonary fungal disease has shown a significant upward trend. The main sources of fungal infections in human lungs are opportunistic fungi: Aspergillus, Cryptococcus, Pneumocystis jirovecii, and endemic fungi. Among them, Aspergillus and Cryptococcus are…

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Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the

Plain Language Summary Colorectal cancer progresses through a well‑defined series of transformations from normal colonic epithelial cells to precursor adenoma lesions that eventually evolve into increasingly more invasive and malignant stages. An improved understanding of the genetic and molecular drivers of colorectal cancer, especially the progression of adenoma to carcinoma,…

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Seroprevalence of Hepatitis B Virus and Associated Factors Among Femal

Introduction Hepatitis B virus (HBV) is a DNA virus belonging to the Hepadnaviridae family.1,2 Despite the availability of a safe and effective vaccine against hepatitis B infection for over two decades now, the overall burden of the disease remains enormous with over 2 billion people infected worldwide and approximately 1…

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H/ACA snoRNP gene family as diagnostic/prognostic biomarkers

Introduction Primary liver cancer, including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma, is the sixth most commonly diagnosed cancer and the fourth leading cause of cancer-related deaths worldwide.1 High metastasis and recurrence rates, as well as limited treatment options, lead to the poor prognosis of advanced HCC.2 Among patients diagnosed with…

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A TME-Related Signature as a Biomarker in Liver Cancer

Introduction As one of the most frequent causes of cancer deaths across the globe, liver cancer, characterized by high mortality, recurrence, metastasis and poor prognosis, is the only one of the top five deadliest cancers to have an annual percentage increase in occurrence.1 Surgery, local destructive therapies, and liver transplantation…

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ANGPTL8/betatrophin improves glucose tolerance | DMSO

Introduction Insulin resistance is a major risk factor for metabolic syndrome (MetS), including type 2 diabetes mellitus (T2DM).1 T2DM is characterized by insulin resistance in the liver.2 Insulin resistance is an abnormal physiological state that occurs when cells are unable to use insulin effectively, leading to T2DM, a major health…

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Bioinformatician | Chicago, IL | The University of Chicago

Bioinformatician | Chicago, IL | The University of Chicago Location: Start New Search: proteomicsremote work from homecomputational biologyvirologyresearch specialistresearch resultsresearch technicianpython rdieticiantitle researchgenomicspredictive analyticsreinsurancebiomedical researchbioinformaticshygienistcomputationalmolecular biologyimmunologydna The University of ChicagoChicago, IL Full-time Preferred Qualifications Education:Bioinformatics, Computational Biology, Computer Science, Mathematics, or a related fieldExperience: Experience in basic programming for bioinformatics…

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Quantitative PCR assay for detection of Helicobacter pylori

Introduction Helicobacter pylori is a common pathogen that infects nearly 50% of the global population.1 Infection with this pathogen causes chronic gastritis, which can cause chronic gastroduodenal diseases such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, and gastric mucosa-associated lymphoid tissue (MALT) B-cell lymphoma.2 Although H. pylori is the…

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Manager, Bioinformatics Group – Stanford University Careers

📁 📅    1 day ago Post Date 📅    91545 Requisition # Stanford University Department of Dermatology is seeking a Manager, Bioinformatics Group (Biostatistician 3) to conduct bioinformatic and statistical analysis and lead a team of bioinformaticians and lab members in order to facilitate biomedical…

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how to start a career in bioinformatics

After getting the required training needed in the field, there are several career opportunities that can be explored, considering that bioinformaticians have a special skill set, which makes them attractive for companies. As an interdisciplinary field of science, bioinformatics combines computer . They study biological and biochemical data at the…

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Multidrug-resistant Tuberculosis Strains in Southeast China

Introduction Multidrug-resistant TB (MDR-TB) infections, which result from transmission of Mycobacterium tuberculosis (MTB) strains with resistance to both rifampicin (RIF) and isoniazid (INH), continue to occur and are a major global public health issue. In 2019 an estimated 362,700 MDR-TB cases were detected worldwide, of which only 56.8% were properly…

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Genotype distribution and prevalence of human papillomavirus

Introduction Cervical cancer (CC) is the second most deadly disease among women in the world and is the leading cause of death from cancer.1 In 2018, there were 570,000 new diseases and 311,000 deaths worldwide.2 Viral infections contribute to 15–20% of all cancers, and several viruses play an important role…

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SNP of the SREK1 gene is associated with COPD in Kashi

Introduction Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disorder that progresses slowly and is characterized by an obstructive ventilatory pattern, which is rarely reversible. The main risk factors are active smoking, genetic factors, and air pollution. In particular, COPD has been a major public health problem and will…

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High tumor mutation burden and DNA repair gene mutations

Introduction Anaplastic lymphoma kinase (ALK)‑fusion genes represent a small but important part of oncogenic driver mutations in NSCLC, accounting for approximately 3%‑7% of all cases worldwide.1,2 Small molecule tyrosine kinase inhibitors (TKIs) are the standard therapy for ALK-rearranged NSCLC. Crizotinib, a first-generation TKI, is the most widely used targeted drug…

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