Tag: TFAM

Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis | Journal of Neuroinflammation

Langlois JA, Rutland-Brown W, Wald MM. The epidemiology and impact of traumatic brain injury: a brief overview. J Head Trauma Rehabil. 2006;21:375–8. doi.org/10.1097/00001199-200609000-00001. Article  PubMed  Google Scholar  Cao HQ, Dong ED. An update on spinal cord injury research. Neurosci Bull. 2013;29:94–102. doi.org/10.1007/s12264-012-1277-8. Article  PubMed  Google Scholar  O’Donnell MJ, Xavier D,…

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As of July 2015, the VCFtools project has been moved to github! Please visit the new website here: vcftools.github.io/man_0112a.html

NAME SYNOPSIS DESCRIPTION EXAMPLES BASIC OPTIONS SITE FILTERING OPTIONS INDIVIDUAL FILTERING OPTIONS GENOTYPE FILTERING OPTIONS OUTPUT OPTIONS COMPARISON OPTIONS AUTHOR NAME VCFtools v0.1.12a − Utilities for the variant call format (VCF) and binary variant call format (BCF) SYNOPSIS vcftools [ –vcf FILE | –gzvcf FILE | –bcf FILE]…

Continue Reading As of July 2015, the VCFtools project has been moved to github! Please visit the new website here: vcftools.github.io/man_0112a.html

Probing the Mammalian Mitochondrial Nucleoid

dc.contributor.author Rajala, Nina dc.date.accessioned 2015-04-29T04:47:49Z dc.date.available 2015-04-29T04:47:49Z dc.date.issued 2015 dc.identifier.isbn 978-951-44-9794-0 – dc.identifier.uri trepo.tuni.fi/handle/10024/96996 dc.description.abstract Mitokondrioiden tärkein tehtävä on energian tuottaminen. Mitokondriot ovat solujen hengityskeskuksia, joissa 90 % tarvitsemastamme energiasta tuotetaan oksidatiivisen fosforylaation kautta elektroninsiirtoketjua apuna käyttäen. Kun mitokondriot eivät toimi kunnolla, tuloksena voi olla energiakriisi, erityisesti lihaksissa, aivoissa ja…

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Dissertations.se: MITOCHONDRIAL DNA REPLICATION

Showing result 1 – 5 of 29 swedish dissertations containing the words Mitochondrial DNA replication. Author : Josefin M. E. Forslund; Sjoerd Wanrooij; Nasim Sabouri; Erik Johansson; Claes Gustafsson; Umeå universitet; []Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitochondria; mitochondrial DNA;…

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Dissertations.se: INITIATION OF DNA REPLICATION

Showing result 1 – 5 of 43 swedish dissertations containing the words initiation of DNA replication. Author : Elisabeth Jemt; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []Keywords : NATURVETENSKAP; NATURAL SCIENCES; mitochondria; mtDNA; DNA replication; Abstract : Mitochondria produce most of the adenosine triphosphate required in a eukaryotic cell and…

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The cGAS-STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy

Abstract The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and deranged signaling of the cGAS-STING axis is closely implicated in multiple sterile inflammatory diseases, including heart failure, myocardial infarction,…

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Dissertations.se: MITOCHONDRIAL CARDIOMYOPATHY

Showing result 1 – 5 of 9 swedish dissertations containing the words mitochondrial cardiomyopathy. Author : Gittan Kollberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Energy metabolism; Mitochondrial Disorders; mtDNA; multiple mtDNA deletions; Alpers-Huttenlocher syndrome; POLG1; GYS1; glycogen synthase; point mutation; Polymerase…

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Korean red ginseng reduces ageing-related issues in postmenopausal women

Although no exact mechanism has been identified for the ageing process in women after menopause, several epidemiological studies have shown that there are many diseases related to ageing in postmenopausal women, such as type 2 diabetes and cardiovascular disease​, both of which are closely linked to oxidative stress and chronic…

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mitochondrial dna damage triggers an ifn mediated immune response

2.6 Mitochondrial Damage-Induced Mitochondrial DNA Release is Central to Chronic Kidney Disease-Induced Type-I-Interferon Response in Vascular Smooth Muscle Cells DNA released from nuclear or mitochondria is the main source of endogenous DNA that activates cGAS-STING pathway. This is thought to be mediated by the presence 75 of leaked mitochondrial DNA…

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