Tag: Waveform

Vaccines | Free Full-Text | Immunogenic Effects and Clinical Applications of Electroporation-Based Treatments

Immunotherapy can now be regarded as an attractive approach for cancer and infectious disease treatments. A variety of novel and varied therapeutic approaches are being discovered through immunology research. Among them, some treatment strategies are based on electrotransfer, also called electroporation (EP). EP is an efficient and safe method that…

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From PyTorch Conference 2023: From Dinosaurs to Seismic Imaging with Intel

by Ramya Ravi, Susan Kahler at Intel Lightning Talk 1: Seismic Data to Subsurface Models with OpenFWI Speaker: Benjamin Consolvo, AI Software Engineering Manager, Intel, LinkedIn Session Overview In this session, Ben begins with an overview of seismic imaging and full waveform inversion (FWI). Seismic imaging and FWI helps us…

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RF & EMS: Top 10 Best | Radio Electroporation Face Beauty Machine in 2021

2021 Top Rated and Reviewed RF&EMS Radio Mesotherapy Electroporation Beauty Machine. ——————————————————— References to the goods: ——————————————————— 1)► 7in1 RF & EMS Radio Mesotherapy Electroporation Beauty Machine ● Buy on AliExpress: s.click.aliexpress.com/e/_99uLid ——————————————————— 2)► 5in1 RF& EMS Mesotherapy Electroporation Face Beauty Machine ● Buy on AliExpress: s.click.aliexpress.com/e/_A1PDxX ——————————————————— 3)► iebilif…

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Harnessing the Electrochemical Effects of Electroporation-Based Therapies to Enhance Anti-tumor Immune Responses

Aycock, K. N., and R. V. Davalos. Irreversible electroporation: background, theory, and review of recent developments in clinical oncology. bioelectricity. 1:214–234, 2019. Article  PubMed  PubMed Central  Google Scholar  Balogh, J., D. Victor, E. H. Asham, S. G. Burroughs, M. Boktour, A. Saharia, Li, R. M. Ghobrial, and H. P. Monsour….

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Building a Neural Network with PyTorch

Building your first neural network could seem like a formidable undertaking, but deep learning frameworks like PyTorch have made the task more accessible than ever. In this article, I’ll explain how to build a neural network using PyTorch—even if you’re brand new to neural networks. We at Gcore recently developed…

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Google Announces New DeepMind Model, Lyria, to Generate High-Quality Music

Google has introduced Google DeepMind’s Lyria, an AI music generation model able to generate vocals, lyrics, and background tracks mimicking the style of popular artists. The model is experimentally available on YouTube through two distinct AI experiments. One of the experiments, Dream Track, aims to let creators generate short music…

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Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

This article aims to provide researchers with a detailed and accessible guide to set up an infant porcine model of hemorrhagic shock. Hemorrhagic shock is the main cause of death in children in the developed world. This study provides the opportunity to compare the response to different therapies for hemorrhagic…

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Long-read sequencing to reclassify variants of uncertain significance in IRDs

(Image Credit: AdobeStock/XaMaps) Reviewed by Debarshi Mustafi, MD, PhD Long-read sequencing technology may be emerging as an option to streamline haplotype analysis in cases in which genetic testing of family members is unfeasible to provide a complete genetic diagnosis,1 according to Debarshi Mustafi, MD, PhD, senior author, from the Department…

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Transepithelial Electrical Impedance Increase Following Porous Substrate Electroporation Enables Label-Free Delivery

Abstract Porous substrate electroporation (PSEP) is a promising new method for delivering molecules such as proteins and nucleic acids into cells for biomedical research. Although many applications have been demonstrated, fundamentals of the PSEP delivery process are not yet well understood, partly because most PSEP studies rely solely on fluorescent…

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Comparison Between Illumina and Nanopore Sequencing Technologies

What is Illumina Sequencing? Illumina sequencing is a second-generation sequencing technology that has become a powerful tool for genomics research. The method uses reversible dye terminator technology to detect the sequence of a DNA molecule. The process begins by fragmenting the DNA sample into short fragments, typically 100-150 base pairs…

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How To Optimize Your Electroporation

Electroporation has transformed the way in which scientists work, allowing the delivery of genetic material, proteins, drugs or other molecules into mammalian, insect, fungal, plant and bacterial cells. Nevertheless, as with all laboratory techniques, it is not without its fair share of pitfalls and disappointments.   Therefore, it is important…

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gladiaio-torchaudio 2.1.0a0 on PyPI – Libraries.io

The aim of torchaudio is to apply PyTorch to the audio domain. By supporting PyTorch, torchaudio follows the same philosophy of providing strong GPU acceleration, having a focus on trainable features through the autograd system, and having consistent style (tensor names and dimension names). Therefore, it is primarily a machine…

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An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants

Protein expression hACE2-hIgG1 was constructed by fusing the extracellular domain of human ACE2 (amino acid 19–615) (UniProt Q9BYF1) to the human IgG1 hinge and Fc (UniProt P01857). H374N and H378N mutations were introduced to inactivate the Zinc metallo-enzyme activity17. HH-120 was constructed by fusing hACE2-hIgG1 with an IgM tailpiece (PTLYNVSLVMSDTAGTCY)33….

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Landscape-scale benefits of protected areas for tropical biodiversity

UN. Kunming Declaration. Declaration from the High-Level Segment of the UN Biodiversity Conference 2020 (Part 1) Under the Theme: “Ecological Civilization: Building a Shared Future for All Life on Earth” (Final Draft) (United Nations Biodiversity Conference, 2021). Chen, C. et al. Global camera trap synthesis highlights the importance of protected…

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Zafar Shahid, PhD on LinkedIn: Google Vertex AI Hackathon

Hi LinkedIn family, Have you heard about #SoundStorm? Isn’t it cool? In case you do not know, let me tell you! Soundstorm is from Google AI Blog, and it’s about a new method for generating high-quality audio signals from text or musical scores using a neural network architecture called SoundStorm….

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Open Source Mathematical Software (Free app)

SageMath is a free open-source mathematics software system licensed under the GPL. It builds on top of many existing open-source packages: NumPy, SciPy, matplotlib, Sympy, Maxima, GAP, FLINT, R and many more. Access their combined power through a common, Python-based language or directly via interfaces or wrappers. Mission Creating a…

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Piezoelectric Transformer-Based High-Voltage Pulse Generator Using Wide-Bandgap Semiconductors for Medical Electroporation Therapy

To demonstrate the proposed proof-of-concept, simulation results of a PT-based HV pulse generator for electroporation are presented in two stages, i.e., the HV capacitor charging circuit shown in Fig. 5 and a pulse-generator full-bridge SiC inverter shown later in Fig. 10. Fig. 5 LTSpice schematic of the PT-based capacitor charger….

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Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

Molecular biology A two-color intramolecular human SERCA2a (2CS) biosensor, based on human cardiac SERCA2a fused to green fluorescent protein (eGFP) and red fluorescent protein (tagRFP) was developed to detect structural changes that are related to the functional changes of SERCA20,22,25. Briefly, tagRFP was genetically fused to the N-terminus of SERCA…

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tacotron – Korea

The Tacotron 2 and WaveGlow model form a text-to-speech system that enables user to synthesise a natural sounding speech from raw transcripts without any …Tacotron (/täkōˌträn/): An end-to-end speech synthesis system by Google. Publications. (March 2017) Tacotron: Towards End-to-End Speech Synthesis.Tacotron 2 (without wavenet). PyTorch implementation of Natural TTS Synthesis By…

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Development of Specialized Microelectrode Arrays with Local Electroporation Functionality

Fabrication and Encapsulation of MEAs Borosilicate glass wafers with 100 mm (4ʺ) diameter were used as substrates for the MEA structures. For a lift-off process (Fig. 2a-1 and a-2), AZ5215E photoresist (MicroChemicals GmbH, Ulm, Germany) was spin-coated and patterned by an image reversal UV photolithography step. Then, 10 nm titanium was deposited…

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Cancers | Free Full-Text | High-Frequency Electroporation and Chemotherapy for the Treatment of Cutaneous Malignancies: Evaluation of Early Clinical Response

Received: 26 April 2023 / Revised: 28 May 2023 / Accepted: 3 June 2023 / Published: 16 June 2023 Round 1 Reviewer 1 Report COMMENTS FOR THE AUTHORS I found the enclosed manuscript (ID: cancers-2267594) entitled “High Frequency Electroporation and Chemotherapy for the Treatment of Cutaneous Malignancies: Evaluation of Early…

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Treadmill for microswimmers allows closer look at behavior – The Source

A team from the McKelvey School of Engineering at Washington University in St. Louis and Massachusetts Institute of Technology has created an acoustic microfluidic method that offers new opportunities to conduct experiments with swimming cells and microorganisms. Meacham “The cells that our collaborators study are powerful swimmers for their size,…

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Engagement 4 OBN survey under way in GoM

Offshore staff OSLO, Norway — TGS and SLB have started acquisition of the Engagement 4 ocean-bottom node (OBN) multiclient survey in the US Gulf of Mexico (GoM). The 152 OCS Block, sparse OBN program is designed to extend contiguous data coverage from earlier phases into the western Green Canyon, an area…

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Maintenance of a Lateral Fluid Percussion Injury Device

Proper care and maintenance are essential for a lateral fluid percussion injury (LFPI) device to function reliably. Here, we demonstrate how to properly clean, fill, and assemble an LFPI device, and ensure that it is adequately maintained for optimal results. Our protocol demonstrates how to maintain the LFPI device properly….

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FastPitch 2 | PyTorch

Model Description This notebook demonstrates a PyTorch implementation of the FastPitch model described in the FastPitch paper. The FastPitch model generates mel-spectrograms and predicts a pitch contour from raw input text. In version 1.1, it does not need any pre-trained aligning model to bootstrap from. To get the audio waveform…

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What Is Google DeepMind?

Google DeepMind is an Alphabet subsidiary focusing on artificial intelligence, machine learning, and neuroscience research. Since its beginnings in 2010, the company has developed AI systems including identifying eye diseases faster and playing complex games like chess, Go, and Shogi.  The History of Google’s DeepMind  The origins of Google DeepMind…

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Scalable continuous-flow electroporation platform enabling T cell transfection for cellular therapy manufacturing

Delivery of mRNA to Jurkat and primary pan T cells To demonstrate the capability of our platform to deliver mRNA, we transfected Jurkat and primary T cells with mRNA encoding GFP. Primary T cells from healthy donors were transfected 4 days after activation with CD3/CD28 antibodies. Both cell types were resuspended…

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Audio Classification with Deep Learning in Python | by Leonie Monigatti | Apr, 2023

Fine-tuning image models to tackle domain shift and class imbalance with PyTorch and torchaudio in audio data Classifying bird calls in soundscapes with Machine Learning (Image drawn by the author) Welcome to another edition of “The Kaggle Blueprints”, where we will analyze Kaggle competitions’ winning solutions for lessons we can…

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NIH 1996 Low Voltage Electroporation Of Cells

The objective of the proposed research is to develop and test a new method, using low voltage (< 15V) waveforms, for electroporating cells, under physiologic conditions. The new method relies upon the unique structure and geometry that results, when living cells are embedded using low pressures, into the holes of…

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Deepgram and PyTorch: The Origins of Our Foundational AI Company

First things first: What’s a foundational AI company? Well, many businesses out there call themselves “AI companies” because they somehow folded AI into their products on the side. Maybe a publishing company has Grammarly somewhere in its editing pipeline. Maybe a marketing firm will play with a GPT model to…

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Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R

This article describes the semi-automated measurement of the amplitudes and latencies of the first five peaks and troughs in the auditory brainstem response waveform. An additional routine compiles and annotates the data into a spreadsheet for experimenter analysis. These free computer routines are executed using the open-source statistical package R….

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Electroporation Instruments and Consumables Market Demand Share Trends Overview Analysis 2022-2029

PRESS RELEASE Published February 28, 2023 Electroporation Instruments and Consumables Market size was valued at USD 221.2 million in 2021 and is estimated to reach at a compound annual growth rate (CAGR) of 6.80% over the forecast period 2022 to 2029. MARKET DYNAMICS: The global electroporation instruments and consumables market…

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