Tag: Waveform

Immunotherapy can now be regarded as an attractive approach for cancer and infectious disease treatments. A variety of novel and varied therapeutic approaches are being discovered through immunology research. Among them, some treatment strategies are based on electrotransfer, also called electroporation (EP). EP is an efficient and safe method that…

by Ramya Ravi, Susan Kahler at Intel Lightning Talk 1: Seismic Data to Subsurface Models with OpenFWI Speaker: Benjamin Consolvo, AI Software Engineering Manager, Intel, LinkedIn Session Overview In this session, Ben begins with an overview of seismic imaging and full waveform inversion (FWI). Seismic imaging and FWI helps us…

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Aycock, K. N., and R. V. Davalos. Irreversible electroporation: background, theory, and review of recent developments in clinical oncology. bioelectricity. 1:214–234, 2019. Article  PubMed  PubMed Central  Google Scholar  Balogh, J., D. Victor, E. H. Asham, S. G. Burroughs, M. Boktour, A. Saharia, Li, R. M. Ghobrial, and H. P. Monsour….

Building your first neural network could seem like a formidable undertaking, but deep learning frameworks like PyTorch have made the task more accessible than ever. In this article, I’ll explain how to build a neural network using PyTorch—even if you’re brand new to neural networks. We at Gcore recently developed…

Google has introduced Google DeepMind’s Lyria, an AI music generation model able to generate vocals, lyrics, and background tracks mimicking the style of popular artists. The model is experimentally available on YouTube through two distinct AI experiments. One of the experiments, Dream Track, aims to let creators generate short music…

This article aims to provide researchers with a detailed and accessible guide to set up an infant porcine model of hemorrhagic shock. Hemorrhagic shock is the main cause of death in children in the developed world. This study provides the opportunity to compare the response to different therapies for hemorrhagic…

(Image Credit: AdobeStock/XaMaps) Reviewed by Debarshi Mustafi, MD, PhD Long-read sequencing technology may be emerging as an option to streamline haplotype analysis in cases in which genetic testing of family members is unfeasible to provide a complete genetic diagnosis,1 according to Debarshi Mustafi, MD, PhD, senior author, from the Department…

Abstract Porous substrate electroporation (PSEP) is a promising new method for delivering molecules such as proteins and nucleic acids into cells for biomedical research. Although many applications have been demonstrated, fundamentals of the PSEP delivery process are not yet well understood, partly because most PSEP studies rely solely on fluorescent…

What is Illumina Sequencing? Illumina sequencing is a second-generation sequencing technology that has become a powerful tool for genomics research. The method uses reversible dye terminator technology to detect the sequence of a DNA molecule. The process begins by fragmenting the DNA sample into short fragments, typically 100-150 base pairs…

Electroporation has transformed the way in which scientists work, allowing the delivery of genetic material, proteins, drugs or other molecules into mammalian, insect, fungal, plant and bacterial cells. Nevertheless, as with all laboratory techniques, it is not without its fair share of pitfalls and disappointments.   Therefore, it is important…

The aim of torchaudio is to apply PyTorch to the audio domain. By supporting PyTorch, torchaudio follows the same philosophy of providing strong GPU acceleration, having a focus on trainable features through the autograd system, and having consistent style (tensor names and dimension names). Therefore, it is primarily a machine…

Protein expression hACE2-hIgG1 was constructed by fusing the extracellular domain of human ACE2 (amino acid 19–615) (UniProt Q9BYF1) to the human IgG1 hinge and Fc (UniProt P01857). H374N and H378N mutations were introduced to inactivate the Zinc metallo-enzyme activity17. HH-120 was constructed by fusing hACE2-hIgG1 with an IgM tailpiece (PTLYNVSLVMSDTAGTCY)33….

UN. Kunming Declaration. Declaration from the High-Level Segment of the UN Biodiversity Conference 2020 (Part 1) Under the Theme: “Ecological Civilization: Building a Shared Future for All Life on Earth” (Final Draft) (United Nations Biodiversity Conference, 2021). Chen, C. et al. Global camera trap synthesis highlights the importance of protected…

Hi LinkedIn family, Have you heard about #SoundStorm? Isn’t it cool? In case you do not know, let me tell you! Soundstorm is from Google AI Blog, and it’s about a new method for generating high-quality audio signals from text or musical scores using a neural network architecture called SoundStorm….

SageMath is a free open-source mathematics software system licensed under the GPL. It builds on top of many existing open-source packages: NumPy, SciPy, matplotlib, Sympy, Maxima, GAP, FLINT, R and many more. Access their combined power through a common, Python-based language or directly via interfaces or wrappers. Mission Creating a…

To demonstrate the proposed proof-of-concept, simulation results of a PT-based HV pulse generator for electroporation are presented in two stages, i.e., the HV capacitor charging circuit shown in Fig. 5 and a pulse-generator full-bridge SiC inverter shown later in Fig. 10. Fig. 5 LTSpice schematic of the PT-based capacitor charger….

Molecular biology A two-color intramolecular human SERCA2a (2CS) biosensor, based on human cardiac SERCA2a fused to green fluorescent protein (eGFP) and red fluorescent protein (tagRFP) was developed to detect structural changes that are related to the functional changes of SERCA20,22,25. Briefly, tagRFP was genetically fused to the N-terminus of SERCA…

The Tacotron 2 and WaveGlow model form a text-to-speech system that enables user to synthesise a natural sounding speech from raw transcripts without any …Tacotron (/täkōˌträn/): An end-to-end speech synthesis system by Google. Publications. (March 2017) Tacotron: Towards End-to-End Speech Synthesis.Tacotron 2 (without wavenet). PyTorch implementation of Natural TTS Synthesis By…

Fabrication and Encapsulation of MEAs Borosilicate glass wafers with 100 mm (4ʺ) diameter were used as substrates for the MEA structures. For a lift-off process (Fig. 2a-1 and a-2), AZ5215E photoresist (MicroChemicals GmbH, Ulm, Germany) was spin-coated and patterned by an image reversal UV photolithography step. Then, 10 nm titanium was deposited…

Received: 26 April 2023 / Revised: 28 May 2023 / Accepted: 3 June 2023 / Published: 16 June 2023 Round 1 Reviewer 1 Report COMMENTS FOR THE AUTHORS I found the enclosed manuscript (ID: cancers-2267594) entitled “High Frequency Electroporation and Chemotherapy for the Treatment of Cutaneous Malignancies: Evaluation of Early…

A team from the McKelvey School of Engineering at Washington University in St. Louis and Massachusetts Institute of Technology has created an acoustic microfluidic method that offers new opportunities to conduct experiments with swimming cells and microorganisms. Meacham “The cells that our collaborators study are powerful swimmers for their size,…

Offshore staff OSLO, Norway — TGS and SLB have started acquisition of the Engagement 4 ocean-bottom node (OBN) multiclient survey in the US Gulf of Mexico (GoM). The 152 OCS Block, sparse OBN program is designed to extend contiguous data coverage from earlier phases into the western Green Canyon, an area…

Proper care and maintenance are essential for a lateral fluid percussion injury (LFPI) device to function reliably. Here, we demonstrate how to properly clean, fill, and assemble an LFPI device, and ensure that it is adequately maintained for optimal results. Our protocol demonstrates how to maintain the LFPI device properly….

Model Description This notebook demonstrates a PyTorch implementation of the FastPitch model described in the FastPitch paper. The FastPitch model generates mel-spectrograms and predicts a pitch contour from raw input text. In version 1.1, it does not need any pre-trained aligning model to bootstrap from. To get the audio waveform…

Google DeepMind is an Alphabet subsidiary focusing on artificial intelligence, machine learning, and neuroscience research. Since its beginnings in 2010, the company has developed AI systems including identifying eye diseases faster and playing complex games like chess, Go, and Shogi.  The History of Google’s DeepMind  The origins of Google DeepMind…

Delivery of mRNA to Jurkat and primary pan T cells To demonstrate the capability of our platform to deliver mRNA, we transfected Jurkat and primary T cells with mRNA encoding GFP. Primary T cells from healthy donors were transfected 4 days after activation with CD3/CD28 antibodies. Both cell types were resuspended…

Fine-tuning image models to tackle domain shift and class imbalance with PyTorch and torchaudio in audio data Classifying bird calls in soundscapes with Machine Learning (Image drawn by the author) Welcome to another edition of “The Kaggle Blueprints”, where we will analyze Kaggle competitions’ winning solutions for lessons we can…

The objective of the proposed research is to develop and test a new method, using low voltage (< 15V) waveforms, for electroporating cells, under physiologic conditions. The new method relies upon the unique structure and geometry that results, when living cells are embedded using low pressures, into the holes of…

First things first: What’s a foundational AI company? Well, many businesses out there call themselves “AI companies” because they somehow folded AI into their products on the side. Maybe a publishing company has Grammarly somewhere in its editing pipeline. Maybe a marketing firm will play with a GPT model to…

This article describes the semi-automated measurement of the amplitudes and latencies of the first five peaks and troughs in the auditory brainstem response waveform. An additional routine compiles and annotates the data into a spreadsheet for experimenter analysis. These free computer routines are executed using the open-source statistical package R….

PRESS RELEASE Published February 28, 2023 Electroporation Instruments and Consumables Market size was valued at USD 221.2 million in 2021 and is estimated to reach at a compound annual growth rate (CAGR) of 6.80% over the forecast period 2022 to 2029. MARKET DYNAMICS: The global electroporation instruments and consumables market…