Tag: XDR
Top Artificial Intelligence Companies to look out for in 2023
The market research firm IDC projected that the global AI market will reach a size of over half a trillion U.S. dollars by 2024. Precedence research suggests that the AI market will grow to over 1.5 trillion U.S. dollars by 2030. Artificial Intelligence (AI) has gripped the world entirely –…
PAN-TB regimens to address growing TB drug resistance
By Dr. Charles Wells, head of therapeutics development at Gates Medical Research Institute As nearly one-quarter of the world’s population is presumed to be infected with Mycobacterium tuberculosis bacteria and are at risk for developing active tuberculosis (TB), the disease represents a major public health challenge globally. As reported by…
A 10-year microbiological study of Pseudomonas aeruginosa strains revealed the circulation of populations resistant to both carbapenems and quaternary ammonium compounds
P. aeruginosa bacterial strains Reference strains Four well-described and genome-available reference strains were used in the present study, ATCC27853 and ATCC15442, obtained from the American Type Culture Collection (ATCC), and PAO1 and PA14, from the collection of Institut Pasteur (Paris, France). Strain ATCC15442 is recommended for disinfectant susceptibility testing44, strain…
Whole-genome sequencing-based analyses of drug-resistant Mycobacterium tuberculosis from Taiwan
Characteristics of the study population Among the 200 DR-TB cases, 146 (73.0%) cases were male, the median age was 66 (interquartile range = 55–78) years, 165 (82.5%) were new cases and 182 (91.0%) cases showed pulmonary TB (Table 1). The majority of DR-TB cases came from northern (74, 37.0%) Taiwan. Among the…
P. aeruginosa retrieved from broiler chickens
Introduction Pseudomonas species are ubiquitous microorganisms that are retrieved from various origins, such as poultry, drinking water, domestic and wild animals, human cases, and different food products.1,2 Pseudomonas infections in poultry are of the highest significance as the infection might spread speedily among the poultry flocks resulting in elevated mortalities…
Molecular epidemiology of CRKP | IDR
Introduction Klebsiella pneumoniae (Kp; K. pneumoniae) is an important hospital and community-acquired pathogen that primarily causes pneumonia, urinary tract infections, bloodstream-associated infections, meningitis, and pyogenic liver abscess.1–3 Carbapenem antibiotics represent the most important treatment for Enterobacteriaceae; however, with the widespread use of such antibiotics, carbapenem-resistant K. pneumoniae (CRKP) is increasingly…
Rapid emergence of extensively drug-resistant Shigella sonnei in France
Antimicrobial susceptibility data of S. sonnei in France Our review of S. sonnei antimicrobial susceptibility data obtained between 2005 and 2021 (based on 7121 isolates received and confirmed at the French National Reference Center for E. coli, Shigella and Salmonella, FNRC-ESS, Institut Pasteur) revealed a sharp increase in the percentage…
Whole-genome sequencing to characterize the genetic structure and transmission risk of Mycobacterium tuberculosis in Yichang city of China
Objective: The burden of both general and drug-resistant tuberculosis in rural areas is higher than that in urban areas in China. To characterize the genetic structure and transmission risk of Mycobacterium tuberculosis in rural China, we used whole genome sequencing to analyze clinical strains collected from patients in two counties…