Tag: XRCC1

Expression of the DNA repair gene XRCC1 in baboon tissues

doi.org/10.1016/0165-7992(95)00053-4Get rights and content Abstract XRCC1 is a DNA repair gene involved in rejoining DNA strand-breaks. We used baboon as an animal model to determine the levels of XRCC1 gene expression in different tisues. Baboons were selected because they are evolutionarily closely related to humans. A single 2.2 kb transcript…

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Browse our XRCC1 ELISA Kits

filter_list Active filters: Target “X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1)” close “Kit” close Application “ELISA” close Read more here: Source link

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Role of XRCC1, XPC, NBN gene polymorphisms in spermatogenesis

doi.org/10.1016/j.genrep.2021.101238Get rights and content Highlights • Infertility affects up to 15% of couples globally, including up to 12% of all men. • Polymorphisms of the DNA repair system genes may potentially lead to inhibition of spermatogenesis. • XRCC1 Arg280His polymorphism may be associated with asthenozoospermia and oligozoospermia. • Our results…

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A meta-analysis of XRCC1 single nucleotide polymorphism and susceptibility to gynecological malignancies

Background: Gynecological malignant tumor is a serious threat to women’s health, cervical cancer, endometrial cancer and ovarian cancer are the most common. The eponymous protein encoded by the XRCC1 (X-ray repair cross complementation 1) gene is an important functional protein in the process of single-stranded DNA damage. Non-synonymous mutations of…

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