Tag: XRCC1

901-MG5 | Anti-XRCC1 (CHICKEN) Antibody Biotrend

Product Details Description: Anti-XRCC1 (CHICKEN) Antibody – 200-901-MG5 Synonyms: Chicken Anti-X-Ray Repair Cross Complementing 1 Antibody, X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 1, X-Ray Repair Cross-Complementing Protein 1, DNA Repair Protein XRCC1, SCAR26, RCC Host Species: Chicken Clonality: Polyclonal Format: IgY Target Details Gene Name: XRCC1  – View…

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Overexpression of XRCC1 is Associated with Poor Survival in Patients with Head and Neck Squamous Carcinoma and Has Potential to Be Used as Targeted Therapy by Synthetic Lethality

Background: Head neck squamous cell carcinoma (HNSCC) is globally prevalent cancer attributed to tobacco habit. Despite the significant advances in early diagnosis and treatment of HNSCC chemo-radio resistance are routinely observed in patients. Aberrant DNA repair mechanisms mainly microhomology mediated DNA end joining (MMEJ) pathway causing deleterious mutations and is…

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(PDF) XRCC1 and XRCC3 DNA repair gene polymorphisms in breast cancer women from the Lodz region of Poland | Anna Sobczuk

(PDF) XRCC1 and XRCC3 DNA repair gene polymorphisms in breast cancer women from the Lodz region of Poland | Anna Sobczuk – Academia.edu Academia.edu uses cookies to personalize content, tailor ads and improve the user experience. By using our site, you agree to our collection of information through the use…

Continue Reading (PDF) XRCC1 and XRCC3 DNA repair gene polymorphisms in breast cancer women from the Lodz region of Poland | Anna Sobczuk

Anti-XRCC1 (phospho S518 + T519 + T523) antibody (AB84417)

Rabbit Polyclonal XRCC1 phospho T519 + T519 antibody. Validated in IHC-P and tested in Mouse, Human samples. Cited in 1 publication. Isotype IgG Host species Rabbit Conjugation Unconjugated Storage buffer pH: 6.8 – 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA Form Liquid Clonality Polyclonal Immunogen The…

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XRCC1 R194W and R399Q Polymorphisms and Colorectal Cancer Risk in a Northeastern Mexican Population

. 2023 Oct 4:2023:5565646. doi: 10.1155/2023/5565646. eCollection 2023. Affiliations Expand Affiliations 1 Facultad de Medicina e Ingeniería en Sistemas Computacionales de Matamoros, Universidad Autónoma de Tamaulipas, Sendero Nacional km 3, CP 87349, Col. San José, Matamoros, Tamaulipas, Mexico. 2 Centro Universitario del Sur, Universidad de Guadalajara, Av. Enrique Arreola Silva…

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Polymorphisms of DNA repair genes XRCC1 and XRCC3, interaction with environmental exposure and risk of chronic gastritis and gastric cancer

The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later. We apologize for any inconvenience caused Polymorphisms of DNA repair genes XRCC1 and XRCC3, interaction with environmental exposure and risk of chronic gastritis and gastric cancer Author(s): Márcia Cristina Duarte, Jucimara Colombo,…

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The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer

Background: Studies on single nucleotide polymorphisms (SNPs) in non-small cell lung cancer (NSCLC) suggest that DNA repair capacity may have prognostic implications for disease recurrence and survival. However, there is no study investigating the relationship between SNPs and the risk of metastasis at the time of initial diagnosis in patients…

Continue Reading The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer

Common variants of eNOS and XRCC1 genes may predict acute skin toxicity in breast cancer patients receiving radiotherapy after breast conserving surgery

Purpose: To evaluate the impact of functional polymorphisms in genes related to DNA repair mechanisms (XRCC1, TP53, MSH2, MSH3, XPD), oxidative stress response (GSTP1, GSTA1, eNOS, SOD2) and fibroblast proliferation (TGFb1) on the risk of acute skin toxicity in breast cancer patients receiving radiotherapy. Material and methods: Skin toxicity was…

Continue Reading Common variants of eNOS and XRCC1 genes may predict acute skin toxicity in breast cancer patients receiving radiotherapy after breast conserving surgery

Sci-Hub | Association Between XRCC1 ARG399GLN and P53 ARG72PRO Polymorphisms and the Risk of Gastric and Colorectal Cancer in Turkish Population. Archives of Industrial Hygiene and Toxicology, 62(3)

Sci-Hub | Association Between XRCC1 ARG399GLN and P53 ARG72PRO Polymorphisms and the Risk of Gastric and Colorectal Cancer in Turkish Population. Archives of Industrial Hygiene and Toxicology, 62(3) | 10.2478/10004-1254-62-2011-2098 ◂ ↓ save Engin, A., Karahalil, B., Karakaya, A., & Engin, A. (2011). Association Between XRCC1 ARG399GLN and P53 ARG72PRO…

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Additional Funding Awarded to Howard University Researcher to Enhance Effectiveness of Immunotherapy in Gastric Cancer

NEW YORK, Aug. 9, 2023 /PRNewswire/ — The DeGregorio Family Foundation with the support of the Price Family Foundation and the Esophageal Cancer Awareness Association has awarded $87,500 to Dawit Kidane-Mulat, PhD, Associate Professor at Howard University College of Medicine to complete his grant. Dr. Kidane-Mulat is working to enhance the effectiveness…

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Machine learning-based ensemble approach in prediction of lung cancer predisposition using XRCC1 gene polymorphism

The employment of machine learning approaches has shown promising results in predicting cancer. In the current study, polymorphisms data of five single nucleotide polymorphisms (SNPs) of DNA repair gene XRCC1 (XRCC1 399, XRCC1 194, XRCC1 206, XRCC1 632, XRCC1 280) of the north Indian population along with four smoking status…

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Association of RAD51, XRCC1, XRCC2, and XRCC3 Polymorphisms with Risk of Breast Cancer

Background: DNA repair genes are among the low-penetrance genes implicated in breast cancer. However variants of DNA repair genes may alter their protein function thus leading to carcinogenesis. Breast cancer is the most common cancer among women in India. The aim of the present study was to identify association, if…

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M938 | Aprataxin And PNKP Like Factor (APLF)

C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. APLF interacts with both XRCC1 and XRCC4, the same components of the single- and double-strand break repair machinery that are bound by PNK and APTX, but not with APTX or DNA ligase III (LIG3). The…

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(PDF) Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells | Larry Stanker

(PDF) Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells | Larry Stanker – Academia.edu Academia.edu uses cookies to personalize content, tailor ads and improve the user experience. By using our site, you agree to our collection of information through the use of…

Continue Reading (PDF) Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells | Larry Stanker

Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19 | Cytogenetic and Genome Research

© 1989 S. Karger AG, Basel Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and…

Continue Reading Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19 | Cytogenetic and Genome Research

Welcome to Pakistan Research Repository: Browsing DSpace

Browsing “PhD Thesis of All Public / Private Sector Universities / DAIs.” by Subject XPD, XRCC1, CYP1A2, Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z or enter first few…

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Effect of XRCC1 Arg399Gln Gene Polymorphism on Survival in Lymphoblastic Leukemia

Introduction: The relevance of the research of the article is conditioned upon the problem of the development of molecular genetic diagnostics to determine the effectiveness of treatment for acute lymphoblastic leukemia in children. The purpose of the article is to identify the polymorphism parameters of the P53 Arg72Pro and XRCC1…

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ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer

Author(s): Vaezi A | Feldman CH | Niedernhofer LJ Journal: Pharmacogenomics and Personalized Medicine ISSN 1178-7066 Volume: 2011; Issue: default; Start page: 47; Date: 2011; Original page ABSTRACT Alec Vaezi1,2, Chelsea H Feldman2, Laura J Niedernhofer2,31Department of Otolaryngology and Head and Neck Surgery, University of Pittsburgh School of Medicine, 2University…

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Mapping Data Summary for Xrcc1

Experiment Type Details Chromosome Reference CROSS Cross Type: BackcrossMapping Panel: Seldin 7 J:1308 Rudert F, et al., Characterization of murine carcinoembryonic antigen gene family members. Mamm Genome. 1992;3(5):262-73 CROSS Cross Type: BackcrossMapping Panel: Seldin 7 J:10993 Saunders AM, et al., A molecular genetic linkage map of mouse chromosome 7. Genomics….

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Recombinant Anti-XRCC1 antibody [EPR4389(2)] (ab134056)

Overview Product name Description Rabbit monoclonal [EPR4389(2)] to XRCC1 Host species Rabbit Tested applications Suitable for: WB, IHC-P, ICC/IFmore detailsUnsuitable for: Flow Cyt or IP Species reactivity Reacts with: …

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Efficient prioritization of CRISPR screen hits by accounting for targeting efficiency of guide RNA | BMC Biology

Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science. 2014;343(6166):84–7. Article  CAS  PubMed  Google Scholar  Manguso RT, Pope HW, Zimmer MD, Brown FD, Yates KB, Miller BC, et al. In vivo CRISPR screening identifies Ptpn2 as a…

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Xrcc1 Targeted Allele Detail MGI Mouse (MGI:3836442)

Xrcc1tm1PmcTargeted Allele Detail Symbol: Xrcc1tm1Pmc Name: X-ray repair complementing defective repair in Chinese hamster cells 1; targeted mutation 1, Peter J McKinnon MGI ID: MGI:3836442 Synonyms: Xrcc1c, Xrcc1Lox Gene: Xrcc1  Location: Chr7:24246124-24272863 bp, + strand  Genetic Position: Chr7, 11.42 cM, cytoband A3-B2 Alliance: Xrcc1tm1Pmc page Allele Type:    Targeted (Conditional ready, No…

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Xrcc1 Gene trapped Allele Detail MGI Mouse (MGI:4257580)

Xrcc1Gt(OST267900)LexGene trapped Allele Detail Symbol: Xrcc1Gt(OST267900)Lex Name: X-ray repair complementing defective repair in Chinese hamster cells 1; gene trap OST267900, Lexicon Genetics MGI ID: MGI:4257580 Gene: Xrcc1  Location: Chr7:24246124-24272863 bp, + strand  Genetic Position: Chr7, 11.42 cM, cytoband A3-B2 Mutant Cell Line:  OST267900 Germline Transmission:  Unknown Parent Cell Line:  Lex-1 (ES Cell)…

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Study Reveals High Turnover and Rescue Effect of Scaffold Protein in Response to Heavy-ion Radiation—-Chinese Academy of Sciences

Researchers from the Microbeam Technology and Applications Group at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS) have discovered the high turnover and rescue effect of an important scaffold protein in response to heavy charged particle radiation. The results were published in Biophysical Journal.   DNA damage response and repair play a decisive role in cell…

Continue Reading Study Reveals High Turnover and Rescue Effect of Scaffold Protein in Response to Heavy-ion Radiation—-Chinese Academy of Sciences

Genetic variants of XRCC1 and risk of hepatocellular carcinoma in chronic hepatitis C patients: British Journal of Biomedical Science: Vol 76, No 2

ABSTRACT Background: Hepatitis C virus (HCV) related liver cirrhosis occurs in about 20% of chronically infected patients over a duration of 10–20 years, and within 5 years approximately 10–20% of these cirrhotic patients will develop hepatocellular carcinoma (HCC). Previous studies report that the X-ray repair cross-complementing group1 gene (XRCC1) is…

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Expression of the DNA repair gene XRCC1 in baboon tissues

doi.org/10.1016/0165-7992(95)00053-4Get rights and content Abstract XRCC1 is a DNA repair gene involved in rejoining DNA strand-breaks. We used baboon as an animal model to determine the levels of XRCC1 gene expression in different tisues. Baboons were selected because they are evolutionarily closely related to humans. A single 2.2 kb transcript…

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Browse our XRCC1 ELISA Kits

filter_list Active filters: Target “X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1)” close “Kit” close Application “ELISA” close Read more here: Source link

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Role of XRCC1, XPC, NBN gene polymorphisms in spermatogenesis

doi.org/10.1016/j.genrep.2021.101238Get rights and content Highlights • Infertility affects up to 15% of couples globally, including up to 12% of all men. • Polymorphisms of the DNA repair system genes may potentially lead to inhibition of spermatogenesis. • XRCC1 Arg280His polymorphism may be associated with asthenozoospermia and oligozoospermia. • Our results…

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A meta-analysis of XRCC1 single nucleotide polymorphism and susceptibility to gynecological malignancies

Background: Gynecological malignant tumor is a serious threat to women’s health, cervical cancer, endometrial cancer and ovarian cancer are the most common. The eponymous protein encoded by the XRCC1 (X-ray repair cross complementation 1) gene is an important functional protein in the process of single-stranded DNA damage. Non-synonymous mutations of…

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