Tag: XRCC1
Effect of XRCC1 Arg399Gln Gene Polymorphism on Survival in Lymphoblastic Leukemia
Introduction: The relevance of the research of the article is conditioned upon the problem of the development of molecular genetic diagnostics to determine the effectiveness of treatment for acute lymphoblastic leukemia in children. The purpose of the article is to identify the polymorphism parameters of the P53 Arg72Pro and XRCC1…
ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer
Author(s): Vaezi A | Feldman CH | Niedernhofer LJ Journal: Pharmacogenomics and Personalized Medicine ISSN 1178-7066 Volume: 2011; Issue: default; Start page: 47; Date: 2011; Original page ABSTRACT Alec Vaezi1,2, Chelsea H Feldman2, Laura J Niedernhofer2,31Department of Otolaryngology and Head and Neck Surgery, University of Pittsburgh School of Medicine, 2University…
Mapping Data Summary for Xrcc1
Experiment Type Details Chromosome Reference CROSS Cross Type: BackcrossMapping Panel: Seldin 7 J:1308 Rudert F, et al., Characterization of murine carcinoembryonic antigen gene family members. Mamm Genome. 1992;3(5):262-73 CROSS Cross Type: BackcrossMapping Panel: Seldin 7 J:10993 Saunders AM, et al., A molecular genetic linkage map of mouse chromosome 7. Genomics….
Recombinant Anti-XRCC1 antibody [EPR4389(2)] (ab134056)
Overview Product name Description Rabbit monoclonal [EPR4389(2)] to XRCC1 Host species Rabbit Tested applications Suitable for: WB, IHC-P, ICC/IFmore detailsUnsuitable for: Flow Cyt or IP Species reactivity Reacts with: …
Efficient prioritization of CRISPR screen hits by accounting for targeting efficiency of guide RNA | BMC Biology
Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science. 2014;343(6166):84–7. Article CAS PubMed Google Scholar Manguso RT, Pope HW, Zimmer MD, Brown FD, Yates KB, Miller BC, et al. In vivo CRISPR screening identifies Ptpn2 as a…
Xrcc1 Targeted Allele Detail MGI Mouse (MGI:3836442)
Xrcc1tm1PmcTargeted Allele Detail Symbol: Xrcc1tm1Pmc Name: X-ray repair complementing defective repair in Chinese hamster cells 1; targeted mutation 1, Peter J McKinnon MGI ID: MGI:3836442 Synonyms: Xrcc1c, Xrcc1Lox Gene: Xrcc1 Location: Chr7:24246124-24272863 bp, + strand Genetic Position: Chr7, 11.42 cM, cytoband A3-B2 Alliance: Xrcc1tm1Pmc page Allele Type: Targeted (Conditional ready, No…
Xrcc1 Gene trapped Allele Detail MGI Mouse (MGI:4257580)
Xrcc1Gt(OST267900)LexGene trapped Allele Detail Symbol: Xrcc1Gt(OST267900)Lex Name: X-ray repair complementing defective repair in Chinese hamster cells 1; gene trap OST267900, Lexicon Genetics MGI ID: MGI:4257580 Gene: Xrcc1 Location: Chr7:24246124-24272863 bp, + strand Genetic Position: Chr7, 11.42 cM, cytoband A3-B2 Mutant Cell Line: OST267900 Germline Transmission: Unknown Parent Cell Line: Lex-1 (ES Cell)…
Study Reveals High Turnover and Rescue Effect of Scaffold Protein in Response to Heavy-ion Radiation—-Chinese Academy of Sciences
Researchers from the Microbeam Technology and Applications Group at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS) have discovered the high turnover and rescue effect of an important scaffold protein in response to heavy charged particle radiation. The results were published in Biophysical Journal. DNA damage response and repair play a decisive role in cell…
Genetic variants of XRCC1 and risk of hepatocellular carcinoma in chronic hepatitis C patients: British Journal of Biomedical Science: Vol 76, No 2
ABSTRACT Background: Hepatitis C virus (HCV) related liver cirrhosis occurs in about 20% of chronically infected patients over a duration of 10–20 years, and within 5 years approximately 10–20% of these cirrhotic patients will develop hepatocellular carcinoma (HCC). Previous studies report that the X-ray repair cross-complementing group1 gene (XRCC1) is…
Expression of the DNA repair gene XRCC1 in baboon tissues
doi.org/10.1016/0165-7992(95)00053-4Get rights and content Abstract XRCC1 is a DNA repair gene involved in rejoining DNA strand-breaks. We used baboon as an animal model to determine the levels of XRCC1 gene expression in different tisues. Baboons were selected because they are evolutionarily closely related to humans. A single 2.2 kb transcript…
Browse our XRCC1 ELISA Kits
filter_list Active filters: Target “X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1)” close “Kit” close Application “ELISA” close Read more here: Source link
Role of XRCC1, XPC, NBN gene polymorphisms in spermatogenesis
doi.org/10.1016/j.genrep.2021.101238Get rights and content Highlights • Infertility affects up to 15% of couples globally, including up to 12% of all men. • Polymorphisms of the DNA repair system genes may potentially lead to inhibition of spermatogenesis. • XRCC1 Arg280His polymorphism may be associated with asthenozoospermia and oligozoospermia. • Our results…
A meta-analysis of XRCC1 single nucleotide polymorphism and susceptibility to gynecological malignancies
Background: Gynecological malignant tumor is a serious threat to women’s health, cervical cancer, endometrial cancer and ovarian cancer are the most common. The eponymous protein encoded by the XRCC1 (X-ray repair cross complementation 1) gene is an important functional protein in the process of single-stranded DNA damage. Non-synonymous mutations of…
